GREMLIN Database
YQJN - Uncharacterized protein YqjN
UniProt: P54551 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 547 (465)
Sequences: 563 (502)
Seq/√Len: 23.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
472_T475_M4.7821.00
472_T476_P4.6391.00
473_S476_P4.5381.00
92_G98_A4.4591.00
17_V21_S4.0981.00
127_D516_P3.9851.00
98_A101_P3.7031.00
42_K145_L3.6191.00
78_L193_L3.3291.00
94_F97_M3.2021.00
254_L319_Q3.1771.00
39_L52_V3.1391.00
244_A293_A3.0541.00
127_D514_Y2.9190.99
75_K194_T2.8810.99
36_Y40_K2.8760.99
94_F98_A2.8750.99
393_V396_L2.7870.99
123_A132_R2.7330.99
250_E253_R2.7220.99
360_A364_A2.6150.99
56_P179_V2.6110.99
392_I395_E2.4620.98
78_L494_V2.4490.98
320_A323_E2.4000.98
304_R312_M2.3880.98
179_V189_H2.3620.98
35_L83_F2.3500.98
24_G167_D2.2460.97
36_Y54_L2.2270.97
150_R154_G2.2250.97
16_L31_L2.1770.96
37_F41_D2.1740.96
390_T393_V2.1710.96
171_N218_S2.1670.96
254_L323_E2.1590.96
393_V397_A2.1490.96
390_T395_E2.1470.96
139_A513_L2.1210.95
32_A54_L2.1050.95
95_K98_A2.0890.95
94_F99_C2.0830.95
195_A460_Y2.0660.95
320_A324_I2.0650.95
396_L400_C2.0650.95
430_T434_I2.0010.94
144_Q162_L1.9840.94
395_E398_S1.9810.93
360_A365_G1.9710.93
393_V398_S1.9560.93
155_H527_S1.9510.93
69_K189_H1.9450.93
432_D436_H1.9010.92
217_G479_N1.8770.91
195_A533_L1.8730.91
217_G512_R1.8630.91
35_L145_L1.8610.91
469_D475_M1.8470.91
443_G446_L1.8350.90
196_C496_V1.8320.90
528_F531_S1.8220.90
10_L515_M1.8100.90
42_K149_E1.8080.90
163_I178_A1.8030.90
460_Y482_Y1.7670.89
121_R520_E1.7480.88
36_Y52_V1.7410.88
81_S144_Q1.7380.88
75_K192_T1.7260.88
248_V295_T1.6950.87
505_D510_T1.6920.86
250_E323_E1.6840.86
198_N236_G1.6740.86
391_K395_E1.6730.86
93_E96_H1.6720.86
143_I522_L1.6720.86
513_L519_F1.6650.86
149_E217_G1.6580.85
63_F200_E1.6520.85
414_P417_P1.6510.85
413_P417_P1.5960.83
156_F531_S1.5850.83
517_Y521_V1.5640.82
251_I407_I1.5620.82
15_S18_Q1.5620.82
467_E528_F1.5590.81
128_W512_R1.5580.81
232_E288_Q1.5550.81
63_F198_N1.5480.81
388_F393_V1.5390.81
97_M100_K1.5350.80
67_L161_L1.5340.80
223_L226_F1.5270.80
42_K52_V1.5250.80
147_M530_I1.5230.80
391_K394_S1.5200.80
92_G99_C1.5180.80
441_R444_I1.5110.79
390_T397_A1.5090.79
92_G101_P1.5070.79
503_G506_P1.5020.79
393_V400_C1.4950.79
142_C146_S1.4880.78
320_A326_S1.4830.78
144_Q199_A1.4810.78
22_I25_S1.4600.77
139_A145_L1.4550.77
80_L165_V1.4490.76
392_I397_A1.4400.76
366_I370_E1.4270.75
90_D292_T1.4240.75
197_L497_L1.4150.75
160_L327_N1.4120.74
120_R124_E1.4000.74
99_C118_R1.3970.74
53_T65_T1.3890.73
142_C240_S1.3850.73
402_E405_P1.3830.73
21_S28_E1.3830.73
136_D507_H1.3820.73
467_E471_Y1.3770.73
70_K73_V1.3610.72
392_I396_L1.3540.71
9_L78_L1.3490.71
397_A406_L1.3390.70
63_F165_V1.3320.70
20_E99_C1.3270.70
243_N290_P1.3250.70
394_S398_S1.3240.69
167_D173_R1.3240.69
40_K54_L1.3210.69
396_L408_V1.3150.69
360_A367_S1.3150.69
8_E149_E1.3150.69
83_F164_T1.3140.69
32_A83_F1.3130.69
11_A15_S1.3090.69
406_L413_P1.3060.68
88_I99_C1.3040.68
436_H440_E1.3030.68
38_I145_L1.2960.68
70_K158_G1.2810.67
218_S456_S1.2800.67
248_V293_A1.2770.67
128_W505_D1.2740.66
357_V361_K1.2640.66
389_S415_L1.2580.65
395_E413_P1.2540.65
321_A407_I1.2450.65
353_F360_A1.2430.64
442_Y446_L1.2290.64
201_P204_E1.2260.63
309_L320_A1.2170.63
81_S140_G1.2110.62
395_E399_L1.2100.62
180_P488_K1.2090.62
141_L162_L1.2000.62
308_E322_E1.2000.62
397_A400_C1.1990.62
362_K365_G1.1990.62
32_A81_S1.1920.61
12_L149_E1.1890.61
314_L318_E1.1760.60
356_L365_G1.1750.60
119_V122_D1.1680.60
77_V309_L1.1510.58
313_L317_A1.1510.58
358_S366_I1.1470.58
136_D169_E1.1450.58
97_M101_P1.1450.58
85_V99_C1.1420.58
57_M177_E1.1410.58
359_R363_R1.1330.57
317_A320_A1.1290.57
373_L377_F1.1280.57
33_E54_L1.1280.57
77_V530_I1.1260.57
40_K52_V1.1250.57
30_A33_E1.1200.56
389_S393_V1.1200.56
392_I398_S1.1190.56
169_E507_H1.1150.56
217_G454_G1.1130.56
278_Q293_A1.1090.56
143_I526_L1.0990.55
256_E290_P1.0970.55
368_E372_A1.0950.55
92_G97_M1.0930.54
36_Y64_L1.0930.54
393_V413_P1.0900.54
24_G173_R1.0840.54
418_A451_Y1.0840.54
121_R124_E1.0840.54
175_M200_E1.0820.54
439_A443_G1.0820.54
217_G461_L1.0800.53
358_S367_S1.0750.53
308_E311_Q1.0740.53
359_R362_K1.0740.53
131_G172_S1.0740.53
55_H63_F1.0670.53
405_P414_P1.0650.52
393_V399_L1.0630.52
388_F392_I1.0620.52
361_K365_G1.0610.52
359_R366_I1.0600.52
133_G241_G1.0580.52
385_D396_L1.0580.52
31_L83_F1.0550.52
483_S486_S1.0530.52
140_G461_L1.0520.52
326_S334_D1.0450.51
156_F160_L1.0440.51
459_S512_R1.0430.51
505_D512_R1.0420.51
363_R366_I1.0400.51
132_R512_R1.0340.50
326_S330_K1.0330.50
94_F101_P1.0320.50
291_H509_W1.0300.50
321_A324_I1.0280.50
427_I446_L1.0250.50
15_S34_Y1.0180.49
122_D504_K1.0160.49
489_N492_L1.0130.49
8_E11_A1.0120.49
252_N278_Q1.0110.49
443_G457_D1.0070.48
228_C247_M1.0030.48
90_D133_G1.0030.48
147_M160_L1.0020.48
29_V33_E1.0020.48
82_H168_E0.9960.48
124_E515_M0.9950.48
283_E293_A0.9900.47
96_H100_K0.9890.47
385_D389_S0.9890.47
137_M506_P0.9880.47
307_S355_E0.9870.47
21_S31_L0.9800.47
352_T356_L0.9800.47
360_A363_R0.9770.46
362_K366_I0.9760.46
387_D391_K0.9710.46
63_F481_G0.9700.46
456_S459_S0.9660.46
214_F520_E0.9650.45
10_L489_N0.9650.45
17_V506_P0.9640.45
358_S372_A0.9590.45
201_P506_P0.9560.45
315_K318_E0.9530.45
389_S392_I0.9480.44
320_A325_M0.9440.44
228_C248_V0.9440.44
368_E371_R0.9430.44
128_W504_K0.9380.44
20_E483_S0.9380.44
311_Q342_Q0.9350.43
15_S38_I0.9330.43
314_L355_E0.9320.43
131_G286_S0.9300.43
334_D469_D0.9280.43
137_M513_L0.9280.43
247_M432_D0.9270.43
408_V526_L0.9260.43
197_L499_V0.9220.43
150_R523_P0.9210.42
142_C214_F0.9210.42
434_I438_A0.9180.42
19_Y205_K0.9150.42
81_S128_W0.9120.42
439_A445_A0.9110.42
194_T493_Y0.9080.42
392_I399_L0.9070.41
358_S364_A0.9030.41
358_S362_K0.9010.41
427_I442_Y0.9000.41
168_E507_H0.9000.41
82_H507_H0.9000.41
71_K157_E0.8990.41
44_Y66_A0.8980.41
504_K508_K0.8980.41
245_N278_Q0.8980.41
82_H136_D0.8980.41
136_D168_E0.8980.41
140_G287_V0.8970.41
306_A320_A0.8940.41
356_L360_A0.8940.41
86_V234_H0.8940.41
372_A375_Y0.8930.41
150_R527_S0.8930.41
202_M288_Q0.8900.40
214_F499_V0.8870.40
134_T513_L0.8830.40
318_E322_E0.8720.39
165_V200_E0.8720.39
233_T238_P0.8710.39
96_H315_K0.8700.39
431_A436_H0.8660.39
405_P411_Y0.8660.39
223_L287_V0.8650.39
428_R435_K0.8630.39
158_G517_Y0.8620.38
330_K336_Q0.8620.38
292_T394_S0.8610.38
383_L391_K0.8600.38
154_G523_P0.8580.38
228_C295_T0.8570.38
455_L461_L0.8560.38
139_A289_T0.8520.38
397_A413_P0.8520.38
70_K250_E0.8520.38
96_H469_D0.8500.38
286_S508_K0.8480.38
12_L42_K0.8470.37
237_E506_P0.8470.37
150_R155_H0.8450.37
22_I28_E0.8430.37
146_S149_E0.8430.37
439_A446_L0.8410.37
13_L200_E0.8400.37
439_A442_Y0.8400.37
389_S397_A0.8390.37
454_G461_L0.8390.37
521_V525_L0.8380.37
514_Y519_F0.8380.37
386_R391_K0.8370.37
29_V58_D0.8360.37
249_S286_S0.8350.37
79_L526_L0.8340.37
197_L506_P0.8320.36
57_M167_D0.8320.36
204_E521_V0.8310.36
329_R344_I0.8280.36
218_S488_K0.8260.36
316_T320_A0.8210.36
245_N275_N0.8200.36
205_K449_V0.8190.36
64_L260_D0.8190.36
392_I413_P0.8170.36
13_L134_T0.8160.35
241_G457_D0.8160.35
169_E511_E0.8120.35
147_M456_S0.8110.35
135_M200_E0.8050.35
68_V148_L0.8000.34
245_N248_V0.7970.34
440_E443_G0.7960.34
88_I291_H0.7960.34
246_L430_T0.7950.34
368_E373_L0.7940.34
76_T133_G0.7940.34
405_P413_P0.7910.34
51_D67_L0.7900.34
351_L360_A0.7890.34
323_E330_K0.7860.34
82_H234_H0.7840.33
168_E234_H0.7840.33
160_L293_A0.7840.33
329_R332_T0.7830.33
140_G215_Y0.7830.33
516_P533_L0.7830.33
285_Y503_G0.7810.33
200_E454_G0.7790.33
488_K491_A0.7790.33
64_L506_P0.7780.33
22_I287_V0.7770.33
347_D360_A0.7760.33
390_T394_S0.7760.33
155_H523_P0.7750.33
64_L177_E0.7730.33
80_L458_L0.7730.33
361_K367_S0.7710.33
455_L494_V0.7690.33
171_N286_S0.7690.33
416_Y458_L0.7680.32
35_L148_L0.7650.32
165_V172_S0.7610.32
170_V173_R0.7570.32
400_C405_P0.7570.32
176_I455_L0.7550.32
83_F141_L0.7540.32
161_L191_I0.7530.32
72_N283_E0.7510.31
386_R389_S0.7500.31
302_M309_L0.7500.31
85_V200_E0.7500.31
135_M506_P0.7470.31
41_D408_V0.7460.31
400_C404_A0.7460.31
372_A378_A0.7450.31
401_K405_P0.7450.31
359_R364_A0.7430.31
80_L172_S0.7410.31
217_G513_L0.7410.31
244_A346_R0.7370.31
118_R121_R0.7370.31
132_R280_D0.7340.30
13_L85_V0.7330.30
232_E235_V0.7310.30
409_L436_H0.7300.30
165_V458_L0.7280.30
359_R365_G0.7270.30
125_S130_F0.7270.30
146_S151_A0.7250.30
330_K334_D0.7240.30
358_S361_K0.7240.30
77_V342_Q0.7220.30
390_T399_L0.7210.30
19_Y34_Y0.7170.29
32_A52_V0.7160.29
218_S496_V0.7150.29
10_L519_F0.7140.29
308_E334_D0.7140.29
141_L164_T0.7140.29
223_L298_N0.7120.29
148_L162_L0.7110.29
11_A14_T0.7090.29
358_S365_G0.7070.29
396_L417_P0.7070.29
437_Y528_F0.7050.29
168_E511_E0.7040.29
82_H511_E0.7040.29
9_L143_I0.7020.29
350_V357_V0.7000.28
133_G276_L0.6940.28
254_L316_T0.6940.28
391_K397_A0.6920.28
147_M156_F0.6900.28
259_A331_K0.6880.28
470_A532_A0.6870.28
397_A401_K0.6850.28
34_Y42_K0.6850.28
136_D234_H0.6820.27
23_T517_Y0.6820.27
233_T289_T0.6820.27
234_H507_H0.6810.27
23_T85_V0.6810.27
497_L514_Y0.6800.27
374_N378_A0.6800.27
222_V306_A0.6790.27
67_L191_I0.6750.27
57_M163_I0.6740.27
514_Y517_Y0.6740.27
140_G286_S0.6740.27
440_E469_D0.6730.27
82_H169_E0.6720.27
433_Q532_A0.6720.27
312_M316_T0.6710.27
63_F80_L0.6700.27
121_R307_S0.6690.27
118_R148_L0.6670.27
251_I317_A0.6660.27
467_E532_A0.6650.26
378_A381_G0.6640.26
315_K319_Q0.6640.26
288_Q502_A0.6610.26
424_D431_A0.6580.26
337_Q340_P0.6570.26
163_I189_H0.6560.26
85_V289_T0.6560.26
321_A325_M0.6560.26
77_V191_I0.6530.26
133_G495_P0.6530.26
121_R318_E0.6530.26
520_E524_D0.6530.26
203_F237_E0.6520.26
65_T161_L0.6510.26
427_I430_T0.6510.26
333_Q337_Q0.6490.26
17_V140_G0.6480.26
138_K482_Y0.6470.26
405_P459_S0.6460.25
507_H511_E0.6460.25
155_H531_S0.6450.25
31_L141_L0.6440.25
39_L148_L0.6440.25
82_H86_V0.6440.25
86_V168_E0.6440.25
100_K118_R0.6430.25
91_Y285_Y0.6430.25
51_D192_T0.6430.25
311_Q315_K0.6420.25
97_M118_R0.6400.25
137_M451_Y0.6390.25
315_K426_L0.6390.25
394_S397_A0.6380.25
366_I371_R0.6370.25
9_L146_S0.6360.25
87_D287_V0.6350.25
70_K499_V0.6350.25
63_F171_N0.6340.25
455_L462_Q0.6340.25
136_D511_E0.6340.25
150_R477_L0.6330.25
167_D501_P0.6320.25
140_G158_G0.6300.25
322_E325_M0.6270.24
215_Y525_L0.6250.24
430_T436_H0.6240.24
315_K357_V0.6240.24
197_L467_E0.6240.24
306_A310_H0.6240.24
84_D220_G0.6220.24
132_R457_D0.6210.24
471_Y510_T0.6210.24
360_A366_I0.6200.24
9_L519_F0.6190.24
171_N513_L0.6170.24
34_Y469_D0.6170.24
357_V364_A0.6170.24
82_H500_G0.6150.24
168_E500_G0.6150.24
95_K248_V0.6140.24
345_E355_E0.6140.24
361_K364_A0.6130.24
396_L413_P0.6130.24
221_K451_Y0.6120.24
73_V515_M0.6100.24
386_R400_C0.6090.24
39_L145_L0.6090.24
130_F510_T0.6080.23
282_K459_S0.6070.23
56_P425_Q0.6060.23
225_G390_T0.6060.23
281_L445_A0.6060.23
43_P125_S0.6050.23
433_Q437_Y0.6030.23
436_H439_A0.6030.23
23_T55_H0.6020.23
12_L513_L0.6020.23
167_D512_R0.6010.23
329_R333_Q0.6010.23
81_S164_T0.5970.23
308_E333_Q0.5970.23
345_E524_D0.5970.23
77_V533_L0.5960.23
165_V416_Y0.5960.23
134_T163_I0.5950.23
226_F313_L0.5950.23
91_Y242_L0.5950.23
35_L235_V0.5940.23
76_T405_P0.5940.23
71_K74_K0.5920.23
433_Q491_A0.5920.23
437_Y441_R0.5920.23
226_F512_R0.5910.23
383_L394_S0.5880.23
319_Q322_E0.5880.23
299_V302_M0.5870.22
354_D358_S0.5840.22
395_E401_K0.5830.22
215_Y478_F0.5830.22
330_K338_F0.5820.22
358_S363_R0.5810.22
43_P345_E0.5810.22
137_M503_G0.5790.22
31_L166_P0.5770.22
315_K436_H0.5770.22
202_M218_S0.5770.22
217_G285_Y0.5770.22
247_M457_D0.5770.22
376_A392_I0.5750.22
214_F525_L0.5750.22
28_E496_V0.5740.22
172_S503_G0.5740.22
35_L81_S0.5730.22
84_D511_E0.5730.22
380_R383_L0.5730.22
69_K159_N0.5720.22
12_L396_L0.5710.22
350_V355_E0.5710.22
140_G143_I0.5700.22
196_C494_V0.5690.22
13_L142_C0.5690.22
390_T396_L0.5690.22
237_E489_N0.5680.22
197_L453_P0.5670.21
446_L512_R0.5670.21
500_G507_H0.5660.21
34_Y145_L0.5650.21
224_A459_S0.5650.21
302_M318_E0.5630.21
393_V401_K0.5630.21
517_Y522_L0.5630.21
99_C509_W0.5620.21
311_Q347_D0.5620.21
148_L318_E0.5610.21
123_A126_G0.5610.21
311_Q370_E0.5610.21
251_I469_D0.5590.21
435_K505_D0.5590.21
99_C120_R0.5580.21
88_I94_F0.5550.21
221_K503_G0.5550.21
284_A508_K0.5540.21
388_F391_K0.5540.21
317_A409_L0.5530.21
305_S320_A0.5520.21
15_S431_A0.5520.21
85_V288_Q0.5510.21
455_L495_P0.5510.21
217_G490_Q0.5510.21
28_E285_Y0.5500.21
132_R226_F0.5490.21
305_S351_L0.5480.21
126_G230_G0.5480.21
136_D217_G0.5480.21
71_K488_K0.5480.21
138_K172_S0.5470.21
441_R446_L0.5470.21
371_R374_N0.5470.21
366_I369_T0.5470.21
80_L202_M0.5450.20
400_C413_P0.5440.20
101_P241_G0.5420.20
393_V406_L0.5420.20
142_C145_L0.5400.20
80_L481_G0.5390.20
200_E203_F0.5390.20
482_Y486_S0.5390.20
39_L66_A0.5390.20
400_C403_D0.5380.20
11_A121_R0.5370.20
86_V136_D0.5370.20
238_P289_T0.5370.20
349_T365_G0.5370.20
86_V507_H0.5350.20
51_D69_K0.5350.20
20_E120_R0.5340.20
365_G368_E0.5330.20
197_L489_N0.5330.20
132_R459_S0.5310.20
345_E354_D0.5310.20
217_G507_H0.5310.20
382_E387_D0.5300.20
401_K406_L0.5300.20
361_K369_T0.5290.20
418_A421_S0.5280.20
72_N148_L0.5280.20
257_L293_A0.5280.20
135_M140_G0.5270.20
282_K285_Y0.5260.20
9_L494_V0.5260.20
405_P457_D0.5260.20
306_A314_L0.5250.20
157_E242_L0.5240.20
160_L484_L0.5240.20
338_F438_A0.5240.20
217_G234_H0.5230.19
295_T449_V0.5230.19
41_D164_T0.5230.19
309_L312_M0.5220.19
165_V238_P0.5220.19
244_A438_A0.5210.19
319_Q445_A0.5200.19
167_D504_K0.5190.19
30_A429_N0.5180.19
20_E88_I0.5180.19
140_G500_G0.5180.19
162_L172_S0.5170.19
327_N330_K0.5170.19
234_H500_G0.5170.19
175_M508_K0.5170.19
374_N466_Q0.5160.19
63_F219_I0.5160.19
323_E363_R0.5150.19
243_N283_E0.5150.19
100_K132_R0.5150.19
335_F338_F0.5150.19
431_A443_G0.5130.19
199_A497_L0.5130.19
93_E97_M0.5120.19
232_E485_P0.5120.19
99_C293_A0.5120.19
131_G202_M0.5110.19
354_D367_S0.5100.19
16_L142_C0.5100.19
19_Y139_A0.5080.19
92_G96_H0.5070.19
136_D500_G0.5070.19
20_E447_R0.5070.19
388_F395_E0.5060.19
307_S318_E0.5060.19
75_K381_G0.5060.19
84_D168_E0.5060.19
215_Y285_Y0.5060.19
354_D364_A0.5040.19
390_T398_S0.5040.19
143_I149_E0.5030.19
19_Y31_L0.5030.19
457_D476_P0.5030.19
354_D429_N0.5020.19
174_G234_H0.5020.19
332_T336_Q0.5020.19
307_S469_D0.5000.19
52_V64_L0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2qyvA 2 0.7916 100 0.653 Contact Map
3mruA 1 0.8135 100 0.669 Contact Map
3pfoA 2 0.7038 100 0.702 Contact Map
3rzaA 2 0.6563 100 0.709 Contact Map
3iszA 2 0.6636 100 0.713 Contact Map
4pqaA 2 0.6709 100 0.715 Contact Map
3gb0A 2 0.6563 100 0.715 Contact Map
3ifeA 2 0.702 100 0.722 Contact Map
2f7vA 2 0.6399 100 0.722 Contact Map
2rb7A 2 0.6344 100 0.726 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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