GREMLIN Database
YQJL - Uncharacterized protein YqjL
UniProt: P54549 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 253 (213)
Sequences: 54979 (44111)
Seq/√Len: 3022.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
97_L121_G3.9171.00
62_A82_E3.1881.00
46_L231_H2.8671.00
226_E229_I2.6591.00
84_E111_W2.6471.00
213_I233_A2.5241.00
184_G216_K2.5221.00
179_L237_V2.4931.00
53_E235_Y2.4921.00
21_H55_G2.4331.00
126_D186_R2.3871.00
97_L120_I2.3701.00
215_A233_A2.2791.00
125_L230_V2.2381.00
16_A68_G2.1711.00
22_R55_G2.0671.00
94_P120_I2.0501.00
84_E118_D1.9931.00
11_T16_A1.9861.00
84_E115_N1.9591.00
84_E88_K1.9561.00
111_W115_N1.9301.00
184_G214_Q1.8991.00
49_D231_H1.8281.00
87_L96_Y1.8071.00
98_A108_T1.8031.00
97_L238_W1.7941.00
204_L210_S1.7811.00
18_H66_K1.7781.00
88_K118_D1.7641.00
105_A127_P1.7421.00
218_S226_E1.7141.00
28_V97_L1.6951.00
29_T55_G1.6881.00
197_Q214_Q1.6581.00
18_H40_S1.6441.00
29_T57_F1.6411.00
110_L114_K1.6361.00
112_A122_M1.6211.00
29_T92_V1.6161.00
19_T86_L1.6101.00
81_K114_K1.5821.00
28_V120_I1.5461.00
34_A64_I1.5121.00
34_A61_R1.5011.00
233_A236_D1.4921.00
178_L207_S1.4911.00
38_T42_T1.4741.00
13_D85_S1.4681.00
33_E61_R1.4641.00
179_L213_I1.4491.00
97_L123_V1.4461.00
202_S206_L1.4421.00
54_F97_L1.4341.00
33_E83_L1.4331.00
77_D114_K1.4241.00
61_R107_I1.4211.00
108_T122_M1.4141.00
80_V110_L1.4121.00
59_Y83_L1.3921.00
49_D235_Y1.3621.00
40_S60_D1.3431.00
111_W119_I1.3391.00
18_H60_D1.3361.00
232_L236_D1.3181.00
115_N118_D1.3181.00
83_L111_W1.2811.00
109_G124_L1.2691.00
110_L113_C1.2351.00
47_M58_T1.2341.00
33_E108_T1.2341.00
229_I233_A1.2251.00
170_Q173_L1.2231.00
40_S66_K1.2191.00
123_V234_I1.2171.00
99_V125_L1.2151.00
207_S210_S1.2131.00
101_H223_H1.2131.00
75_T78_Q1.2121.00
22_R58_T1.1771.00
15_C62_A1.1721.00
32_F99_V1.1681.00
53_E239_C1.1551.00
24_G27_G1.1511.00
111_W118_D1.1421.00
197_Q201_S1.1401.00
124_L127_P1.1351.00
88_K115_N1.1331.00
102_S220_H1.1311.00
23_K55_G1.1301.00
37_G64_I1.1291.00
17_F82_E1.1241.00
229_I232_L1.1221.00
49_D52_D1.1091.00
235_Y239_C1.1021.00
40_S58_T1.1021.00
30_I54_F1.1001.00
86_L90_A1.0981.00
182_S200_H1.0941.00
57_F86_L1.0911.00
42_T223_H1.0911.00
37_G102_S1.0841.00
142_M146_H1.0721.00
32_F56_I1.0691.00
201_S205_S1.0481.00
123_V179_L1.0481.00
182_S214_Q1.0411.00
215_A218_S1.0371.00
211_G233_A1.0201.00
35_G102_S1.0151.00
182_S212_W1.0131.00
181_L215_A1.0081.00
92_V96_Y0.9851.00
28_V54_F0.9791.00
230_V234_I0.9701.00
33_E98_A0.9681.00
19_T90_A0.9611.00
179_L211_G0.9591.00
219_S225_D0.9581.00
101_H221_N0.9491.00
99_V234_I0.9461.00
31_V87_L0.9451.00
22_R47_M0.9441.00
49_D228_H0.9441.00
54_F238_W0.9401.00
51_D56_I0.9391.00
121_G177_P0.9311.00
96_Y119_I0.9311.00
12_I85_S0.9301.00
172_H206_L0.9261.00
218_S225_D0.9211.00
215_A229_I0.9201.00
171_V174_G0.9161.00
204_L212_W0.9151.00
77_D110_L0.9111.00
59_Y86_L0.9091.00
182_S197_Q0.9051.00
213_I236_D0.9041.00
15_C68_G0.9031.00
80_V107_I0.9001.00
152_L156_H0.9001.00
54_F239_C0.8961.00
32_F43_W0.8951.00
125_L223_H0.8801.00
84_E114_K0.8801.00
60_D65_G0.8781.00
100_S108_T0.8761.00
228_H232_L0.8711.00
158_E162_S0.8641.00
201_S204_L0.8591.00
113_C170_Q0.8581.00
143_H146_H0.8521.00
152_L155_T0.8501.00
202_S205_S0.8491.00
155_T158_E0.8491.00
201_S214_Q0.8411.00
201_S212_W0.8361.00
87_L111_W0.8331.00
181_L233_A0.8281.00
31_V96_Y0.8261.00
28_V94_P0.8231.00
78_Q81_K0.8141.00
21_H57_F0.8131.00
44_K58_T0.8121.00
48_A51_D0.8041.00
96_Y118_D0.8031.00
57_F90_A0.8021.00
213_I229_I0.8021.00
91_D94_P0.7931.00
33_E59_Y0.7881.00
17_F67_S0.7861.00
45_P48_A0.7831.00
144_K147_T0.7801.00
162_S165_E0.7781.00
79_Q103_Y0.7661.00
47_M56_I0.7631.00
85_S88_K0.7621.00
85_S89_A0.7541.00
49_D53_E0.7541.00
175_N208_N0.7521.00
28_V121_G0.7521.00
184_G217_N0.7461.00
80_V114_K0.7451.00
112_A119_I0.7441.00
125_L222_I0.7411.00
157_A161_K0.7371.00
81_K85_S0.7371.00
218_S222_I0.7361.00
61_R103_Y0.7311.00
30_I56_I0.7281.00
163_L166_L0.7261.00
87_L92_V0.7261.00
159_F163_L0.7161.00
73_K78_Q0.7161.00
199_L202_S0.7111.00
29_T54_F0.7061.00
122_M178_L0.7061.00
143_H147_T0.7041.00
29_T96_Y0.7041.00
36_Y103_Y0.7031.00
27_G55_G0.7021.00
30_I99_V0.7011.00
81_K84_E0.7011.00
98_A119_I0.7001.00
31_V83_L0.6951.00
157_A160_S0.6921.00
121_G237_V0.6911.00
80_V111_W0.6911.00
54_F235_Y0.6901.00
185_E217_N0.6881.00
162_S166_L0.6881.00
84_E87_L0.6871.00
101_H126_D0.6851.00
101_H125_L0.6841.00
180_V210_S0.6801.00
41_E44_K0.6801.00
158_E161_K0.6791.00
40_S59_Y0.6781.00
200_H212_W0.6771.00
30_I238_W0.6741.00
61_R79_Q0.6721.00
100_S105_A0.6681.00
123_V237_V0.6651.00
149_K152_L0.6651.00
60_D66_K0.6631.00
231_H235_Y0.6581.00
52_D235_Y0.6541.00
232_L235_Y0.6521.00
126_D222_I0.6521.00
174_G178_L0.6501.00
121_G238_W0.6491.00
47_M51_D0.6491.00
162_S169_R0.6481.00
160_S164_Q0.6481.00
106_V128_A0.6471.00
12_I15_C0.6441.00
198_N201_S0.6441.00
159_F162_S0.6361.00
99_V123_V0.6341.00
227_P231_H0.6321.00
98_A111_W0.6321.00
57_F92_V0.6311.00
30_I97_L0.6311.00
109_G129_L0.6291.00
34_A59_Y0.6271.00
25_S55_G0.6251.00
183_S222_I0.6231.00
110_L170_Q0.6221.00
126_D183_S0.6221.00
215_A226_E0.6211.00
112_A176_M0.6191.00
153_E156_H0.6181.00
160_S163_L0.6171.00
55_G92_V0.6151.00
126_D182_S0.6111.00
161_K164_Q0.6091.00
96_Y120_I0.6091.00
217_N226_E0.6081.00
18_H67_S0.6081.00
48_A52_D0.6061.00
17_F62_A0.6051.00
100_S104_G0.6051.00
181_L230_V0.6011.00
154_G158_E0.5981.00
123_V238_W0.5971.00
164_Q167_K0.5951.00
11_T14_G0.5951.00
46_L230_V0.5911.00
148_R152_L0.5911.00
155_T162_S0.5891.00
44_K48_A0.5881.00
119_I176_M0.5851.00
13_D78_Q0.5841.00
62_A79_Q0.5831.00
186_R220_H0.5821.00
31_V98_A0.5821.00
148_R151_M0.5821.00
211_G236_D0.5771.00
43_W47_M0.5771.00
77_D81_K0.5771.00
151_M155_T0.5771.00
76_A110_L0.5741.00
151_M154_G0.5721.00
23_K26_S0.5711.00
165_E169_R0.5691.00
13_D81_K0.5641.00
37_G103_Y0.5601.00
24_G55_G0.5571.00
158_E163_L0.5561.00
61_R64_I0.5541.00
184_G197_Q0.5541.00
113_C173_L0.5451.00
154_G162_S0.5451.00
35_G101_H0.5431.00
38_T221_N0.5431.00
196_W199_L0.5411.00
93_K118_D0.5411.00
155_T159_F0.5401.00
149_K153_E0.5401.00
80_V84_E0.5391.00
11_T15_C0.5381.00
102_S221_N0.5361.00
154_G157_A0.5331.00
156_H160_S0.5321.00
36_Y64_I0.5281.00
174_G207_S0.5281.00
234_I238_W0.5251.00
30_I50_I0.5241.00
46_L49_D0.5241.00
50_I234_I0.5221.00
150_M153_E0.5211.00
42_T101_H0.5141.00
200_H204_L0.5141.00
79_Q107_I0.5131.00
105_A124_L0.5121.00
23_K51_D0.5091.00
43_W46_L0.5051.00
32_F50_I0.5041.00
155_T166_L0.5011.00
150_M154_G0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4inzA 1 0.8933 100 0.217 Contact Map
1ehyA 1 0.8933 100 0.24 Contact Map
4psuA 1 0.913 100 0.245 Contact Map
1iupA 2 0.9091 100 0.246 Contact Map
2pujA 4 0.917 100 0.253 Contact Map
3om8A 4 0.9091 100 0.256 Contact Map
3oosA 1 0.8972 100 0.257 Contact Map
4opmA 2 0.9447 100 0.26 Contact Map
4lxhA 2 0.917 100 0.262 Contact Map
1c4xA 3 0.917 100 0.263 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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