GREMLIN Database
YQJF - Uncharacterized protein YqjF
UniProt: P54543 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 242 (222)
Sequences: 586 (458)
Seq/√Len: 30.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
39_R42_V5.2061.00
32_P54_Q4.4691.00
29_A225_L3.9851.00
64_L67_L3.8731.00
60_L98_I3.7831.00
38_L48_L3.3431.00
199_Q229_K3.0261.00
55_A88_T2.9261.00
177_R188_Y2.9171.00
86_L211_T2.8811.00
49_D175_R2.7401.00
135_A153_A2.5761.00
27_L154_Y2.5120.99
32_P56_W2.4710.99
84_L127_M2.3640.99
155_R202_E2.3090.99
194_H232_D2.3010.99
127_M140_S2.2100.99
105_A111_V2.1490.98
30_H226_H2.0680.98
82_P106_D1.9790.97
69_A110_A1.9770.97
166_D169_D1.9630.97
33_V180_T1.9520.97
45_V92_Y1.9480.97
25_D229_K1.9240.97
41_L101_F1.8570.96
47_E91_T1.8440.96
114_A122_Y1.8200.95
120_L178_L1.7960.95
39_R48_L1.7860.95
23_W62_F1.7430.94
34_D54_Q1.6890.93
62_F83_E1.6780.93
22_T228_A1.6680.92
50_T55_A1.6660.92
119_H182_Y1.6590.92
23_W85_N1.6540.92
167_S170_Y1.6280.91
23_W83_E1.5500.89
21_Q178_L1.5480.89
85_N100_F1.5460.89
130_E137_D1.5440.89
25_D46_L1.5420.89
26_V60_L1.5260.89
24_N65_T1.5060.88
25_D131_K1.4950.88
203_A225_L1.4940.87
104_D125_A1.4910.87
219_P223_P1.4890.87
82_P129_S1.4810.87
61_P152_A1.4680.87
25_D227_Y1.4390.85
151_H209_T1.4380.85
112_L116_T1.4340.85
42_V48_L1.4030.84
97_G188_Y1.4030.84
68_R72_L1.3960.84
68_R73_P1.3760.83
17_W236_W1.3670.82
42_V99_Y1.3590.82
38_L42_V1.3560.82
21_Q235_F1.3530.82
220_E223_P1.3440.81
30_H58_S1.3340.81
56_W169_D1.3310.81
139_V151_H1.3070.79
18_I61_P1.2920.79
62_F81_F1.2900.78
168_L172_L1.2790.78
78_A110_A1.2760.78
40_A48_L1.2730.77
33_V38_L1.2590.77
123_F142_R1.2480.76
131_K134_D1.2380.75
64_L233_V1.2340.75
46_L88_T1.2310.75
192_H236_W1.2290.75
118_F189_E1.1830.72
37_I128_K1.1700.71
192_H234_L1.1430.69
91_T96_P1.1100.67
64_L81_F1.1010.66
111_V124_Y1.0990.66
84_L152_A1.0990.66
98_I185_K1.0850.65
61_P65_T1.0760.65
46_L99_Y1.0700.64
32_P223_P1.0620.64
187_Y238_L1.0560.63
58_S169_D1.0530.63
67_L110_A1.0520.63
25_D149_A1.0520.63
99_Y171_W1.0470.62
85_N122_Y1.0440.62
162_T166_D1.0420.62
91_T196_W1.0370.62
60_L64_L1.0350.62
84_L144_N1.0310.61
26_V127_M1.0270.61
85_N193_H1.0250.61
166_D170_Y1.0190.60
110_A120_L1.0120.60
61_P84_L1.0100.60
75_I156_P0.9970.59
76_P211_T0.9950.58
119_H238_L0.9910.58
157_I183_R0.9860.58
50_T123_F0.9850.58
62_F127_M0.9830.57
116_T184_N0.9720.57
136_I156_P0.9660.56
27_L84_L0.9540.55
39_R45_V0.9510.55
27_L174_E0.9430.54
46_L186_L0.9400.54
115_R123_F0.9340.54
39_R184_N0.9330.54
38_L95_K0.9330.54
109_L233_V0.9260.53
155_R200_N0.9250.53
154_Y157_I0.9230.53
104_D123_F0.9200.52
34_D66_N0.9170.52
182_Y187_Y0.9160.52
19_M235_F0.9130.52
100_F176_Y0.9120.52
96_P99_Y0.9120.52
29_A152_A0.9050.51
35_V50_T0.9040.51
88_T101_F0.9000.51
30_H64_L0.8990.51
31_W55_A0.8950.50
88_T99_Y0.8930.50
77_G82_P0.8900.50
52_N56_W0.8870.50
184_N213_A0.8860.50
28_F173_T0.8860.50
17_W234_L0.8810.49
79_R179_Y0.8770.49
173_T198_L0.8660.48
172_L175_R0.8570.47
113_G116_T0.8550.47
59_M76_P0.8530.47
96_P179_Y0.8510.47
164_E225_L0.8450.46
178_L235_F0.8280.45
38_L216_I0.8270.45
58_S225_L0.8200.44
64_L231_Q0.8190.44
108_R124_Y0.8160.44
42_V59_M0.8140.44
52_N147_E0.8140.44
108_R112_L0.8130.44
22_T25_D0.8050.43
30_H79_R0.8010.43
78_A109_L0.8000.43
58_S185_K0.7950.43
21_Q175_R0.7880.42
60_L115_R0.7840.42
173_T196_W0.7820.41
51_Y74_V0.7800.41
74_V80_A0.7800.41
57_I214_H0.7790.41
148_A213_A0.7790.41
156_P227_Y0.7760.41
179_Y213_A0.7750.41
19_M67_L0.7650.40
44_S129_S0.7650.40
27_L176_Y0.7630.40
172_L195_P0.7620.40
28_F121_P0.7590.40
148_A209_T0.7580.40
169_D226_H0.7580.40
50_T170_Y0.7550.39
155_R159_A0.7380.38
98_I226_H0.7330.38
176_Y180_T0.7310.38
64_L118_F0.7310.38
128_K159_A0.7270.37
87_R196_W0.7250.37
21_Q30_H0.7240.37
94_G184_N0.7200.37
110_A178_L0.7180.37
63_M80_A0.7180.37
129_S136_I0.7180.37
102_S214_H0.7160.36
26_V61_P0.7150.36
150_F208_N0.7130.36
21_Q120_L0.7110.36
19_M178_L0.7080.36
48_L88_T0.7080.36
185_K198_L0.7070.36
137_D151_H0.7050.36
85_N176_Y0.7040.36
178_L237_P0.7030.35
48_L191_I0.7010.35
83_E122_Y0.6940.35
64_L113_G0.6940.35
33_V219_P0.6880.34
136_I142_R0.6830.34
41_L57_I0.6820.34
162_T199_Q0.6810.34
34_D37_I0.6810.34
22_T134_D0.6780.34
26_V231_Q0.6760.34
73_P205_I0.6760.34
29_A222_D0.6750.33
166_D209_T0.6740.33
122_Y176_Y0.6730.33
67_L191_I0.6710.33
66_N72_L0.6690.33
41_L216_I0.6640.33
20_R66_N0.6620.33
67_L109_L0.6560.32
75_I97_G0.6510.32
85_N196_W0.6490.32
45_V184_N0.6470.31
33_V99_Y0.6460.31
52_N57_I0.6460.31
23_W28_F0.6450.31
81_F95_K0.6450.31
132_N202_E0.6440.31
17_W70_R0.6440.31
190_D236_W0.6430.31
45_V185_K0.6410.31
63_M126_D0.6400.31
38_L92_Y0.6400.31
53_G94_G0.6380.31
93_K179_Y0.6380.31
59_M152_A0.6360.31
22_T65_T0.6340.31
137_D200_N0.6340.31
65_T182_Y0.6290.30
55_A219_P0.6260.30
153_A156_P0.6200.30
19_M189_E0.6170.29
135_A155_R0.6120.29
151_H155_R0.6110.29
197_L201_A0.6090.29
104_D142_R0.6080.29
52_N164_E0.6070.29
106_D151_H0.6070.29
147_E156_P0.6040.29
138_Y200_N0.6030.29
213_A219_P0.6030.29
109_L165_K0.6020.28
106_D127_M0.5990.28
109_L116_T0.5970.28
99_Y186_L0.5960.28
58_S227_Y0.5950.28
150_F189_E0.5950.28
107_H238_L0.5910.28
26_V46_L0.5910.28
41_L115_R0.5900.28
58_S226_H0.5900.28
191_I235_F0.5890.28
102_S168_L0.5890.28
17_W56_W0.5870.27
105_A233_V0.5860.27
42_V53_G0.5860.27
107_H112_L0.5860.27
63_M82_P0.5840.27
58_S88_T0.5830.27
103_L235_F0.5830.27
78_A126_D0.5820.27
61_P83_E0.5820.27
98_I122_Y0.5820.27
98_I173_T0.5800.27
81_F169_D0.5780.27
69_A186_L0.5780.27
40_A80_A0.5770.27
27_L227_Y0.5760.27
51_Y167_S0.5750.27
131_K141_K0.5740.27
187_Y237_P0.5710.26
67_L233_V0.5700.26
31_W103_L0.5680.26
77_G166_D0.5680.26
163_A167_S0.5680.26
180_T190_D0.5670.26
25_D237_P0.5620.26
57_I222_D0.5610.26
69_A118_F0.5600.26
95_K190_D0.5580.26
54_Q134_D0.5580.26
234_L237_P0.5560.26
81_F113_G0.5560.26
67_L231_Q0.5500.25
19_M76_P0.5470.25
118_F180_T0.5450.25
82_P127_M0.5450.25
228_A231_Q0.5440.25
110_A189_E0.5430.25
126_D141_K0.5430.25
102_S123_F0.5420.25
123_F144_N0.5420.25
203_A230_K0.5410.25
88_T172_L0.5400.25
74_V203_A0.5390.25
65_T80_A0.5380.24
33_V36_S0.5370.24
156_P199_Q0.5370.24
34_D158_S0.5320.24
35_V54_Q0.5300.24
103_L118_F0.5290.24
26_V98_I0.5290.24
124_Y143_K0.5260.24
20_R71_Y0.5250.24
180_T228_A0.5240.24
146_K159_A0.5180.23
59_M208_N0.5180.23
110_A233_V0.5170.23
157_I202_E0.5160.23
72_L97_G0.5150.23
92_Y179_Y0.5150.23
113_G185_K0.5150.23
109_L220_E0.5120.23
156_P201_A0.5120.23
141_K185_K0.5110.23
147_E165_K0.5100.23
34_D72_L0.5100.23
23_W193_H0.5090.23
25_D190_D0.5080.23
98_I178_L0.5070.23
95_K164_E0.5070.23
37_I205_I0.5060.23
197_L202_E0.5050.23
193_H196_W0.5010.22
55_A168_L0.5010.22
21_Q86_L0.5010.22
35_V194_H0.5010.22
152_A205_I0.5000.22
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4jmdA 4 0.9339 99.9 0.734 Contact Map
3c8wA 6 0.9132 99.9 0.752 Contact Map
3bgtA 6 0.9091 99.8 0.761 Contact Map
4zboA 4 0.9504 99.6 0.815 Contact Map
3bh2A 6 0.9215 99.4 0.835 Contact Map
3cmbA 4 0.9421 97.5 0.908 Contact Map
1k3sA 2 0.157 7.3 0.972 Contact Map
3q6kA 1 0.7975 4.2 0.975 Contact Map
4zcnA 3 0.314 2.2 0.978 Contact Map
3m7kA 2 0.2066 2 0.979 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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