GREMLIN Database
YQJE - Uncharacterized protein YqjE
UniProt: P54542 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 371 (340)
Sequences: 29682 (21140)
Seq/√Len: 1146.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
61_T132_E3.4351.00
184_A241_E3.1711.00
32_K36_S2.9791.00
205_I276_G2.7951.00
184_A243_H2.7931.00
13_E30_V2.7551.00
94_Y349_K2.6801.00
32_K44_E2.6741.00
190_A199_G2.5951.00
63_K130_T2.5761.00
70_T130_T2.5511.00
182_R243_H2.5501.00
185_I209_A2.4931.00
264_K268_E2.4801.00
186_F279_E2.4511.00
186_F277_R2.4101.00
184_A279_E2.3761.00
260_V264_K2.3761.00
307_K364_A2.3611.00
34_K37_D2.3401.00
186_F241_E2.3341.00
35_F60_C2.3311.00
120_V363_V2.2341.00
206_A242_V2.2311.00
182_R245_L2.2151.00
206_A244_I2.2131.00
182_R281_E2.1811.00
30_V34_K2.1171.00
206_A229_F2.1111.00
261_Q265_A2.1051.00
230_E243_H2.0901.00
61_T130_T2.0621.00
70_T132_E2.0591.00
120_V124_E2.0231.00
184_A281_E2.0111.00
207_S210_I1.8981.00
308_I364_A1.8881.00
302_K306_A1.8851.00
87_K347_N1.8761.00
86_V90_V1.8741.00
38_L119_K1.8561.00
147_K151_R1.8251.00
228_R245_L1.8191.00
301_A365_I1.8141.00
17_I30_V1.8071.00
208_K211_S1.7621.00
88_P91_E1.7591.00
29_K33_R1.7581.00
33_R37_D1.7471.00
209_A267_F1.7191.00
202_A242_V1.7051.00
40_V62_L1.6861.00
26_E29_K1.6801.00
268_E272_A1.6571.00
364_A367_E1.6531.00
188_K200_I1.6521.00
34_K38_L1.6391.00
306_A311_P1.6311.00
12_L16_Q1.6201.00
257_E261_Q1.6181.00
7_L359_A1.6071.00
93_G353_E1.6001.00
32_K58_L1.5941.00
10_E34_K1.5871.00
208_K274_M1.5871.00
13_E16_Q1.5801.00
262_K265_A1.5781.00
207_S211_S1.5691.00
119_K123_E1.5501.00
13_E26_E1.5481.00
28_C77_M1.5431.00
189_T240_D1.5401.00
200_I205_I1.5401.00
231_G242_V1.5401.00
30_V33_R1.5321.00
9_E13_E1.5291.00
31_L77_M1.5251.00
327_A333_T1.5211.00
148_A151_R1.5101.00
113_A358_T1.5091.00
72_Y134_I1.5071.00
204_T214_P1.5051.00
299_E302_K1.4901.00
41_D63_K1.4861.00
29_K44_E1.4831.00
212_K269_E1.4651.00
195_E198_K1.4621.00
33_R36_S1.4581.00
36_S44_E1.4501.00
255_K258_A1.4471.00
64_G130_T1.4401.00
181_V246_A1.4251.00
13_E17_I1.4161.00
179_A256_M1.3841.00
258_A262_K1.3801.00
62_L122_K1.3741.00
212_K266_A1.3741.00
182_R283_E1.3721.00
260_V282_I1.3681.00
185_I206_A1.3651.00
32_K42_V1.3521.00
208_K273_D1.3511.00
148_A152_S1.3481.00
36_S42_V1.3461.00
261_Q264_K1.3431.00
109_A355_L1.3421.00
109_A350_M1.3301.00
271_A278_A1.3231.00
183_A244_I1.3211.00
302_K314_L1.3061.00
305_A361_M1.3001.00
357_K360_E1.2971.00
267_F278_A1.2811.00
15_V97_T1.2801.00
19_S27_I1.2771.00
65_T128_H1.2741.00
161_A164_S1.2691.00
72_Y156_A1.2641.00
73_F114_M1.2601.00
304_A364_A1.2591.00
25_A29_K1.2561.00
34_K119_K1.2551.00
264_K280_V1.2481.00
9_E12_L1.2461.00
169_G174_A1.2281.00
157_S161_A1.2261.00
265_A269_E1.2221.00
25_A56_G1.2161.00
10_E30_V1.2151.00
200_I276_G1.2151.00
356_V360_E1.2121.00
10_E116_E1.2071.00
7_L116_E1.2061.00
122_K125_N1.2001.00
220_E252_V1.1921.00
29_K32_K1.1891.00
185_I205_I1.1791.00
265_A268_E1.1711.00
8_L12_L1.1691.00
68_T129_G1.1691.00
300_I304_A1.1631.00
308_I360_E1.1601.00
304_A308_I1.1571.00
14_L27_I1.1491.00
222_T259_Q1.1471.00
7_L112_A1.1431.00
43_K61_T1.1181.00
353_E357_K1.1151.00
258_A261_Q1.1091.00
73_F366_I1.1091.00
21_T141_S1.1051.00
203_I229_F1.1011.00
295_D299_E1.1001.00
203_I231_G1.0991.00
299_E303_K1.0941.00
15_V100_T1.0901.00
124_E363_V1.0891.00
31_L111_L1.0801.00
301_A334_V1.0791.00
124_E367_E1.0751.00
12_L352_I1.0711.00
41_D61_T1.0701.00
260_V284_V1.0651.00
157_S163_D1.0591.00
210_I244_I1.0541.00
57_N137_V1.0531.00
351_P354_E1.0461.00
252_V255_K1.0431.00
28_C58_L1.0301.00
167_K170_N1.0291.00
69_D129_G1.0291.00
85_G347_N1.0261.00
40_V60_C1.0261.00
94_Y351_P1.0221.00
26_E30_V1.0081.00
93_G351_P1.0061.00
303_K306_A1.0041.00
114_M133_F1.0031.00
167_K172_I0.9991.00
204_T210_I0.9981.00
215_L222_T0.9961.00
118_I133_F0.9921.00
13_E34_K0.9921.00
117_A363_V0.9891.00
350_M355_L0.9851.00
17_I26_E0.9831.00
116_E119_K0.9791.00
262_K266_A0.9761.00
77_M135_I0.9681.00
35_F115_F0.9671.00
10_E119_K0.9561.00
75_S111_L0.9551.00
266_A269_E0.9551.00
303_K307_K0.9501.00
266_A270_A0.9491.00
215_L262_K0.9451.00
226_I246_A0.9411.00
28_C32_K0.9391.00
360_E364_A0.9341.00
269_E273_D0.9341.00
91_E94_Y0.9301.00
7_L355_L0.9301.00
22_K138_G0.9271.00
14_L30_V0.9251.00
77_M111_L0.9251.00
164_S343_I0.9241.00
306_A310_R0.9191.00
298_V334_V0.9131.00
83_G92_N0.9111.00
42_V60_C0.9091.00
38_L122_K0.9091.00
206_A210_I0.9071.00
183_A267_F0.9031.00
120_V360_E0.9031.00
169_G173_V0.9001.00
181_V260_V0.8971.00
167_K174_A0.8951.00
65_T127_E0.8941.00
62_L118_I0.8931.00
203_I242_V0.8901.00
208_K212_K0.8881.00
363_V367_E0.8861.00
268_E271_A0.8851.00
230_E233_T0.8831.00
359_A363_V0.8811.00
183_A209_A0.8801.00
147_K325_V0.8751.00
300_I365_I0.8751.00
212_K270_A0.8741.00
253_P257_E0.8731.00
117_A362_V0.8701.00
118_I122_K0.8701.00
213_M263_M0.8681.00
69_D157_S0.8681.00
182_R235_T0.8621.00
217_R220_E0.8611.00
304_A307_K0.8581.00
204_T207_S0.8581.00
162_L362_V0.8561.00
234_Q237_I0.8541.00
40_V118_I0.8541.00
186_F240_D0.8531.00
159_G163_D0.8521.00
27_I77_M0.8491.00
177_T288_G0.8481.00
337_A340_Y0.8431.00
210_I226_I0.8421.00
354_E357_K0.8401.00
87_K90_V0.8381.00
174_A316_T0.8361.00
323_A333_T0.8351.00
180_K247_E0.8351.00
13_E33_R0.8301.00
34_K115_F0.8301.00
300_I303_K0.8241.00
296_Q300_I0.8221.00
296_Q299_E0.8221.00
79_T98_D0.8161.00
235_T245_L0.8141.00
121_L126_I0.8131.00
229_F242_V0.8091.00
59_I132_E0.8061.00
197_E217_R0.8061.00
159_G164_S0.8051.00
269_E272_A0.8031.00
175_A321_S0.8031.00
270_A273_D0.8011.00
73_F117_A0.7991.00
208_K214_P0.7871.00
156_A161_A0.7851.00
216_G222_T0.7851.00
177_T250_S0.7851.00
355_L359_A0.7781.00
257_E260_V0.7731.00
210_I229_F0.7711.00
167_K171_I0.7691.00
43_K153_M0.7651.00
28_C44_E0.7631.00
298_V302_K0.7611.00
213_M224_A0.7611.00
146_A150_D0.7611.00
294_G297_V0.7571.00
70_T157_S0.7561.00
22_K141_S0.7541.00
254_E258_A0.7531.00
159_G331_I0.7491.00
31_L115_F0.7481.00
321_S335_N0.7451.00
305_A308_I0.7441.00
11_F95_V0.7431.00
200_I275_G0.7431.00
265_A272_A0.7391.00
226_I244_I0.7391.00
190_A238_V0.7381.00
21_T24_E0.7331.00
68_T130_T0.7301.00
181_V282_I0.7291.00
120_V359_A0.7271.00
113_A362_V0.7261.00
353_E356_V0.7261.00
43_K59_I0.7241.00
183_A280_V0.7241.00
185_I244_I0.7241.00
20_E81_V0.7221.00
28_C56_G0.7211.00
325_V328_G0.7181.00
117_A359_A0.7161.00
71_I366_I0.7141.00
287_P328_G0.7131.00
62_L133_F0.7131.00
64_G67_Q0.7111.00
40_V122_K0.7101.00
124_E127_E0.7101.00
179_A260_V0.7071.00
248_A259_Q0.7061.00
63_K67_Q0.7051.00
111_L135_I0.7031.00
332_P335_N0.6991.00
201_S239_C0.6971.00
10_E13_E0.6971.00
156_A163_D0.6951.00
120_V123_E0.6951.00
185_I278_A0.6951.00
336_L340_Y0.6931.00
205_I274_M0.6911.00
301_A361_M0.6901.00
42_V58_L0.6901.00
91_E96_K0.6891.00
31_L135_I0.6891.00
257_E284_V0.6871.00
342_Q345_T0.6851.00
113_A117_A0.6841.00
113_A359_A0.6841.00
87_K91_E0.6821.00
211_S214_P0.6821.00
58_L135_I0.6821.00
74_T136_T0.6801.00
12_L15_V0.6781.00
188_K345_T0.6771.00
10_E14_L0.6761.00
250_S256_M0.6731.00
42_V45_D0.6721.00
20_E23_H0.6721.00
70_T129_G0.6701.00
339_G350_M0.6671.00
72_Y157_S0.6661.00
208_K270_A0.6641.00
158_Y297_V0.6621.00
38_L115_F0.6621.00
39_G42_V0.6601.00
360_E363_V0.6591.00
325_V329_H0.6571.00
264_K282_I0.6561.00
15_V19_S0.6531.00
31_L58_L0.6531.00
214_P274_M0.6521.00
270_A274_M0.6521.00
224_A248_A0.6511.00
119_K122_K0.6511.00
181_V263_M0.6501.00
361_M365_I0.6481.00
12_L95_V0.6471.00
169_G172_I0.6451.00
304_A361_M0.6431.00
116_E359_A0.6431.00
282_I285_M0.6421.00
144_I148_A0.6411.00
37_D119_K0.6411.00
134_I149_L0.6411.00
209_A244_I0.6351.00
10_E115_F0.6331.00
26_E33_R0.6311.00
24_E138_G0.6311.00
158_Y161_A0.6301.00
256_M287_P0.6291.00
202_A239_C0.6251.00
40_V133_F0.6251.00
10_E112_A0.6221.00
305_A312_S0.6221.00
64_G68_T0.6211.00
236_N249_R0.6211.00
8_L356_V0.6201.00
159_G162_L0.6201.00
8_L95_V0.6191.00
308_I361_M0.6171.00
140_E344_H0.6151.00
304_A365_I0.6131.00
204_T211_S0.6121.00
176_P223_T0.6121.00
46_D56_G0.6091.00
336_L361_M0.6091.00
96_K349_K0.6081.00
150_D329_H0.6071.00
35_F40_V0.6061.00
11_F352_I0.6011.00
267_F280_V0.6001.00
21_T142_G0.5961.00
85_G346_K0.5951.00
224_A227_G0.5941.00
342_Q347_N0.5931.00
75_S114_M0.5931.00
14_L111_L0.5911.00
230_E245_L0.5901.00
253_P328_G0.5891.00
294_G299_E0.5871.00
114_M162_L0.5861.00
180_K235_T0.5861.00
138_G141_S0.5851.00
297_V334_V0.5841.00
223_T227_G0.5831.00
352_I356_V0.5831.00
185_I276_G0.5831.00
167_K173_V0.5821.00
14_L112_A0.5801.00
271_A276_G0.5801.00
228_R243_H0.5801.00
95_V352_I0.5791.00
8_L352_I0.5791.00
253_P287_P0.5791.00
297_V300_I0.5771.00
86_V89_V0.5751.00
261_Q268_E0.5751.00
209_A270_A0.5751.00
160_Y362_V0.5731.00
22_K25_A0.5731.00
57_N149_L0.5711.00
256_M260_V0.5691.00
179_A282_I0.5681.00
209_A266_A0.5681.00
250_S259_Q0.5671.00
143_L286_Y0.5611.00
204_T208_K0.5601.00
74_T134_I0.5601.00
11_F112_A0.5591.00
55_A148_A0.5591.00
122_K126_I0.5581.00
155_T161_A0.5581.00
185_I202_A0.5561.00
59_I134_I0.5561.00
44_E56_G0.5561.00
36_S41_D0.5551.00
309_G312_S0.5541.00
65_T130_T0.5531.00
157_S331_I0.5521.00
192_A227_G0.5511.00
173_V314_L0.5501.00
246_A263_M0.5501.00
86_V349_K0.5501.00
271_A277_R0.5491.00
338_V358_T0.5491.00
295_D332_P0.5471.00
302_K313_E0.5471.00
156_A164_S0.5461.00
136_T322_D0.5441.00
146_A326_I0.5431.00
10_E38_L0.5421.00
225_N247_E0.5421.00
181_V280_V0.5421.00
172_I315_Q0.5401.00
64_G125_N0.5391.00
209_A213_M0.5391.00
43_K46_D0.5351.00
126_I367_E0.5331.00
323_A335_N0.5321.00
65_T68_T0.5311.00
157_S164_S0.5311.00
200_I277_R0.5301.00
45_D152_S0.5291.00
17_I27_I0.5291.00
20_E94_Y0.5281.00
337_A341_E0.5271.00
210_I246_A0.5261.00
95_V100_T0.5251.00
254_E257_E0.5241.00
175_A337_A0.5241.00
163_D175_A0.5241.00
212_K273_D0.5231.00
230_E241_E0.5231.00
7_L11_F0.5231.00
161_A323_A0.5221.00
205_I270_A0.5211.00
192_A225_N0.5211.00
158_Y332_P0.5211.00
138_G144_I0.5191.00
286_Y325_V0.5181.00
302_K311_P0.5171.00
342_Q349_K0.5171.00
75_S110_G0.5161.00
248_A254_E0.5151.00
97_T100_T0.5141.00
263_M280_V0.5141.00
189_T202_A0.5131.00
336_L339_G0.5131.00
71_I158_Y0.5121.00
257_E285_M0.5121.00
160_Y164_S0.5121.00
176_P318_G0.5111.00
272_A277_R0.5101.00
190_A195_E0.5101.00
207_S214_P0.5101.00
77_M137_V0.5091.00
69_D128_H0.5091.00
141_S144_I0.5091.00
160_Y163_D0.5071.00
340_Y343_I0.5061.00
81_V234_Q0.5031.00
217_R221_E0.5031.00
331_I334_V0.5021.00
202_A238_V0.5011.00
340_Y354_E0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3gb0A 2 1 100 0.196 Contact Map
3rzaA 2 0.9919 100 0.21 Contact Map
3pfoA 2 0.9811 100 0.246 Contact Map
3ifeA 2 0.9704 100 0.265 Contact Map
1cg2A 4 0.973 100 0.278 Contact Map
4pqaA 2 0.9461 100 0.283 Contact Map
3iszA 2 0.9353 100 0.284 Contact Map
1fnoA 2 0.9488 100 0.286 Contact Map
2qyvA 2 0.9353 100 0.29 Contact Map
4mmoA 2 0.9515 100 0.292 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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