DLDH2 - BACSU - GREMLIN Contacts

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DLDH2 - Dihydrolipoyl dehydrogenase

UniProt:	P54533	Sequences: MATEYDVVILGGGTGGYVAAIRAAQLGLKTAVVEKEKLGGTCLHKGCIPSKALLRSAEVYRTAREADQFGVETAGVSLNFEKVQQRKQAVVDKLAAGVNHLMKKGKIDVYTGYGRILGPSIFSPLPGTISVERGNGEENDMLIPKQVIIATGSRPRMLPGLEVDGKSVLTSDEALQMEELPQSIIIVGGGVIGIEWASMLHDFGVKVTVIEYADRILPTEDLEISKEMESLLKKKGIQFITGAKVLPDTMTKTSDDISIQAEKDGETVTYSAEKMLVSIGRQANIEGIGLENTDIVTENGMISVNESCQTKESHIYAIGDVIGGLQLAHVASHEGIIAVEHFAGLNPHPLDPTLVPKCIYSSPEAASVGLTEDEAKANGHNVKIGKFPFMAIGKALVYGESDGFVKIVADRDTDDILGVHMIGPHVTDMISEAGLAKVLDATPWEVGQTIHPHPTLSEAIGEAALAADGKAIHF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	474 (444)
Sequences:	13767 (9130)
Seq/√Len:	433.3

ECOLI - STHA DLDH GSHR RCLA HCAD NORW
BACSU - DLDH2 DLDH1 DLDH3
HALSA - DLDH Q9HSN0 Q9HP48 Q9HR27
SULSO - Q97VD9 Q97Z19 Q97XZ3 Q97WE3 Q97VQ4 Q97Y24 Q97YT2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
185_I	272_A	4.350	1.00
35_K	113_Y	4.069	1.00
305_N	309_Q	4.000	1.00
183_S	206_K	3.054	1.00
419_V	433_A	3.043	1.00
381_N	412_D	2.809	1.00
206_K	238_Q	2.809	1.00
208_T	240_I	2.808	1.00
5_Y	108_D	2.766	1.00
154_R	286_E	2.744	1.00
118_G	128_T	2.719	1.00
4_E	145_K	2.671	1.00
5_Y	31_A	2.653	1.00
229_E	233_K	2.635	1.00
289_G	292_N	2.634	1.00
4_E	143_I	2.605	1.00
381_N	411_R	2.579	1.00
19_A	148_I	2.558	1.00
128_T	141_M	2.515	1.00
432_E	451_H	2.489	1.00
180_L	205_V	2.480	1.00
222_L	373_D	2.472	1.00
144_P	147_V	2.444	1.00
410_D	413_T	2.423	1.00
156_R	282_Q	2.420	1.00
117_L	130_S	2.410	1.00
31_A	110_Y	2.406	1.00
183_S	273_E	2.394	1.00
154_R	284_N	2.373	1.00
370_L	378_N	2.263	1.00
414_D	444_W	2.262	1.00
370_L	375_A	2.246	1.00
383_K	411_R	2.240	1.00
185_I	210_I	2.233	1.00
8_V	142_L	2.228	1.00
130_S	141_M	2.225	1.00
115_R	130_S	2.199	1.00
7_V	23_A	2.181	1.00
415_D	440_D	2.165	1.00
297_T	301_M	2.158	1.00
338_A	342_F	2.118	1.00
421_M	426_V	2.075	1.00
117_L	141_M	2.038	1.00
161_L	247_P	2.014	1.00
15_G	318_I	2.012	1.00
214_D	242_G	2.004	1.00
128_T	143_I	2.000	1.00
382_V	408_V	1.998	1.00
170_T	173_E	1.980	1.00
194_I	209_V	1.973	1.00
8_V	33_V	1.924	1.00
72_E	79_N	1.923	1.00
154_R	282_Q	1.919	1.00
436_A	441_A	1.900	1.00
8_V	129_I	1.861	1.00
146_Q	314_H	1.860	1.00
372_E	376_K	1.823	1.00
72_E	77_S	1.800	1.00
8_V	144_P	1.780	1.00
201_H	206_K	1.766	1.00
373_D	377_A	1.755	1.00
6_D	145_K	1.749	1.00
116_I	147_V	1.745	1.00
79_N	82_K	1.742	1.00
149_I	321_V	1.712	1.00
407_I	419_V	1.697	1.00
184_I	205_V	1.692	1.00
306_E	349_P	1.675	1.00
148_I	342_F	1.668	1.00
8_V	31_A	1.667	1.00
309_Q	313_S	1.666	1.00
215_R	225_S	1.655	1.00
258_S	271_S	1.640	1.00
194_I	361_S	1.635	1.00
10_L	114_G	1.625	1.00
169_L	274_K	1.623	1.00
364_E	427_T	1.623	1.00
246_L	260_Q	1.619	1.00
372_E	406_K	1.618	1.00
33_V	142_L	1.607	1.00
375_A	382_V	1.605	1.00
184_I	200_L	1.603	1.00
110_Y	142_L	1.592	1.00
223_E	386_K	1.580	1.00
182_Q	273_E	1.545	1.00
6_D	29_K	1.540	1.00
380_H	417_L	1.538	1.00
212_Y	244_K	1.525	1.00
182_Q	206_K	1.519	1.00
169_L	177_M	1.516	1.00
99_N	111_T	1.503	1.00
240_I	243_A	1.501	1.00
7_V	28_L	1.500	1.00
247_P	260_Q	1.497	1.00
442_T	445_E	1.496	1.00
256_D	271_S	1.494	1.00
316_Y	341_H	1.493	1.00
227_E	422_I	1.470	1.00
38_L	109_V	1.454	1.00
82_K	85_Q	1.446	1.00
307_S	341_H	1.444	1.00
374_E	377_A	1.443	1.00
308_C	322_I	1.443	1.00
59_V	62_T	1.434	1.00
146_Q	342_F	1.428	1.00
65_E	68_Q	1.421	1.00
7_V	148_I	1.412	1.00
22_R	340_E	1.411	1.00
151_T	321_V	1.411	1.00
407_I	464_A	1.411	1.00
202_D	235_K	1.409	1.00
201_H	237_I	1.403	1.00
208_T	238_Q	1.381	1.00
5_Y	110_Y	1.374	1.00
120_S	314_H	1.373	1.00
31_A	142_L	1.357	1.00
381_N	410_D	1.343	1.00
253_T	256_D	1.342	1.00
375_A	408_V	1.335	1.00
174_A	200_L	1.324	1.00
185_I	259_I	1.323	1.00
384_I	408_V	1.321	1.00
72_E	82_K	1.311	1.00
88_Q	92_D	1.302	1.00
29_K	108_D	1.292	1.00
253_T	258_S	1.290	1.00
309_Q	314_H	1.278	1.00
260_Q	267_T	1.278	1.00
224_I	422_I	1.277	1.00
230_S	233_K	1.275	1.00
112_G	131_V	1.269	1.00
148_I	318_I	1.255	1.00
293_T	312_E	1.247	1.00
228_M	422_I	1.245	1.00
223_E	406_K	1.244	1.00
115_R	289_G	1.240	1.00
189_G	216_I	1.236	1.00
45_K	172_D	1.235	1.00
410_D	415_D	1.234	1.00
221_D	406_K	1.233	1.00
215_R	222_L	1.228	1.00
84_Q	88_Q	1.214	1.00
372_E	384_I	1.203	1.00
312_E	315_I	1.198	1.00
243_A	264_D	1.196	1.00
222_L	226_K	1.195	1.00
32_V	102_M	1.193	1.00
405_V	459_A	1.186	1.00
439_L	445_E	1.185	1.00
433_A	460_I	1.181	1.00
335_G	339_V	1.180	1.00
224_I	404_F	1.179	1.00
220_E	367_S	1.172	1.00
157_M	170_T	1.161	1.00
210_I	270_Y	1.160	1.00
116_I	149_I	1.153	1.00
220_E	357_K	1.144	1.00
211_E	241_T	1.135	1.00
407_I	433_A	1.133	1.00
290_L	295_I	1.133	1.00
374_E	378_N	1.132	1.00
389_F	423_G	1.129	1.00
231_L	234_K	1.128	1.00
10_L	149_I	1.110	1.00
365_A	422_I	1.110	1.00
187_V	275_M	1.108	1.00
209_V	239_F	1.107	1.00
113_Y	287_G	1.104	1.00
215_R	229_E	1.104	1.00
15_G	331_A	1.101	1.00
169_L	173_E	1.096	1.00
120_S	312_E	1.096	1.00
296_V	303_S	1.095	1.00
431_S	452_P	1.094	1.00
380_H	410_D	1.093	1.00
36_E	45_K	1.092	1.00
229_E	241_T	1.091	1.00
358_C	452_P	1.088	1.00
63_A	66_A	1.086	1.00
167_S	274_K	1.086	1.00
302_I	321_V	1.086	1.00
229_E	239_F	1.085	1.00
304_V	317_A	1.083	1.00
230_S	234_K	1.078	1.00
26_L	343_A	1.077	1.00
303_S	311_K	1.076	1.00
295_I	302_I	1.075	1.00
357_K	367_S	1.074	1.00
21_I	105_G	1.073	1.00
159_P	163_V	1.072	1.00
116_I	129_I	1.071	1.00
386_K	404_F	1.070	1.00
117_L	128_T	1.069	1.00
115_R	132_E	1.065	1.00
108_D	140_D	1.064	1.00
232_L	237_I	1.059	1.00
55_R	59_V	1.059	1.00
102_M	107_I	1.058	1.00
425_H	428_D	1.057	1.00
252_K	255_D	1.056	1.00
233_K	238_Q	1.050	1.00
234_K	402_D	1.047	1.00
228_M	365_A	1.047	1.00
318_I	338_A	1.046	1.00
371_T	374_E	1.044	1.00
261_A	270_Y	1.042	1.00
366_A	430_I	1.042	1.00
308_C	338_A	1.040	1.00
99_N	103_K	1.037	1.00
376_K	382_V	1.036	1.00
184_I	274_K	1.035	1.00
115_R	292_N	1.034	1.00
383_K	414_D	1.034	1.00
304_V	322_I	1.033	1.00
354_L	437_K	1.032	1.00
33_V	114_G	1.032	1.00
431_S	457_S	1.029	1.00
80_F	84_Q	1.028	1.00
110_Y	140_D	1.020	1.00
81_E	178_E	1.020	1.00
441_A	445_E	1.019	1.00
185_I	270_Y	1.016	1.00
297_T	323_G	1.013	1.00
85_Q	89_A	1.011	1.00
131_V	142_L	1.008	1.00
370_L	374_E	1.001	1.00
92_D	96_A	0.997	1.00
194_I	232_L	0.997	1.00
375_A	380_H	0.995	1.00
244_K	263_K	0.995	1.00
414_D	443_P	0.993	1.00
89_A	93_K	0.991	1.00
297_T	303_S	0.986	1.00
368_V	437_K	0.985	1.00
240_I	270_Y	0.984	1.00
372_E	382_V	0.983	1.00
243_A	263_K	0.983	1.00
22_R	26_L	0.979	1.00
183_S	271_S	0.975	1.00
169_L	174_A	0.973	1.00
28_L	343_A	0.972	1.00
405_V	421_M	0.971	1.00
358_C	427_T	0.971	1.00
183_S	205_V	0.967	1.00
337_I	350_L	0.967	1.00
116_I	144_P	0.967	1.00
26_L	340_E	0.962	1.00
179_E	274_K	0.961	1.00
28_L	146_Q	0.960	1.00
12_G	38_L	0.957	1.00
183_S	208_T	0.954	1.00
119_P	314_H	0.951	1.00
74_A	77_S	0.951	1.00
285_I	296_V	0.950	1.00
386_K	406_K	0.950	1.00
224_I	420_H	0.947	1.00
60_Y	64_R	0.947	1.00
147_V	315_I	0.945	1.00
61_R	235_K	0.943	1.00
63_A	73_T	0.942	1.00
295_I	312_E	0.939	1.00
6_D	28_L	0.938	1.00
187_V	279_I	0.935	1.00
227_E	230_S	0.934	1.00
165_G	173_E	0.933	1.00
366_A	426_V	0.932	1.00
210_I	261_A	0.928	1.00
100_H	104_K	0.925	1.00
115_R	287_G	0.921	1.00
261_A	264_D	0.921	1.00
380_H	408_V	0.920	1.00
216_I	241_T	0.920	1.00
28_L	145_K	0.916	1.00
252_K	256_D	0.915	1.00
5_Y	29_K	0.915	1.00
216_I	229_E	0.915	1.00
309_Q	341_H	0.915	1.00
216_I	239_F	0.914	1.00
162_E	165_G	0.913	1.00
258_S	267_T	0.912	1.00
189_G	211_E	0.912	1.00
12_G	32_V	0.911	1.00
57_A	202_D	0.907	1.00
231_L	422_I	0.906	1.00
184_I	276_L	0.902	1.00
28_L	342_F	0.898	1.00
146_Q	316_Y	0.896	1.00
226_K	230_S	0.886	1.00
293_T	315_I	0.884	1.00
215_R	373_D	0.882	1.00
338_A	341_H	0.881	1.00
231_L	235_K	0.880	1.00
416_I	433_A	0.877	1.00
227_E	231_L	0.877	1.00
18_V	332_S	0.876	1.00
33_V	131_V	0.874	1.00
116_I	293_T	0.870	1.00
436_A	446_V	0.865	1.00
156_R	279_I	0.864	1.00
226_K	229_E	0.862	1.00
33_V	112_G	0.858	1.00
56_S	83_V	0.858	1.00
325_L	355_V	0.857	1.00
295_I	311_K	0.856	1.00
287_G	290_L	0.856	1.00
91_V	94_L	0.856	1.00
10_L	129_I	0.855	1.00
10_L	288_I	0.854	1.00
160_G	163_V	0.854	1.00
23_A	339_V	0.853	1.00
44_H	95_A	0.851	1.00
102_M	109_V	0.851	1.00
339_V	343_A	0.849	1.00
166_K	252_K	0.848	1.00
187_V	277_V	0.848	1.00
112_G	135_N	0.846	1.00
98_V	102_M	0.846	1.00
87_K	91_V	0.846	1.00
410_D	417_L	0.845	1.00
120_S	128_T	0.843	1.00
84_Q	87_K	0.843	1.00
117_L	292_N	0.839	1.00
317_A	321_V	0.839	1.00
73_T	76_V	0.837	1.00
186_I	276_L	0.836	1.00
210_I	240_I	0.836	1.00
337_I	341_H	0.834	1.00
283_A	301_M	0.834	1.00
368_V	434_G	0.834	1.00
22_R	25_Q	0.833	1.00
116_I	289_G	0.833	1.00
177_M	181_P	0.829	1.00
193_G	211_E	0.827	1.00
157_M	163_V	0.827	1.00
253_T	271_S	0.825	1.00
67_D	82_K	0.825	1.00
116_I	292_N	0.825	1.00
168_V	277_V	0.824	1.00
351_D	438_V	0.822	1.00
289_G	293_T	0.821	1.00
441_A	446_V	0.821	1.00
7_V	339_V	0.820	1.00
58_E	62_T	0.819	1.00
231_L	402_D	0.819	1.00
432_E	435_L	0.818	1.00
438_V	448_Q	0.817	1.00
187_V	245_V	0.816	1.00
372_E	408_V	0.816	1.00
294_D	312_E	0.815	1.00
61_R	64_R	0.815	1.00
285_I	297_T	0.814	1.00
309_Q	316_Y	0.813	1.00
19_A	335_G	0.810	1.00
56_S	86_R	0.805	1.00
23_A	28_L	0.805	1.00
54_L	199_M	0.804	1.00
8_V	147_V	0.803	1.00
191_V	359_I	0.802	1.00
224_I	365_A	0.802	1.00
132_E	136_G	0.798	1.00
22_R	339_V	0.797	1.00
215_R	226_K	0.795	1.00
243_A	261_A	0.794	1.00
213_A	218_P	0.792	1.00
210_I	243_A	0.792	1.00
93_K	396_L	0.792	1.00
246_L	263_K	0.791	1.00
147_V	314_H	0.791	1.00
183_S	272_A	0.789	1.00
376_K	379_G	0.789	1.00
42_C	47_C	0.788	1.00
201_H	235_K	0.788	1.00
53_L	84_Q	0.783	1.00
307_S	349_P	0.783	1.00
114_G	118_G	0.783	1.00
173_E	176_Q	0.781	1.00
388_P	391_A	0.780	1.00
61_R	202_D	0.779	1.00
85_Q	178_E	0.778	1.00
81_E	85_Q	0.776	1.00
330_V	355_V	0.776	1.00
364_E	425_H	0.775	1.00
19_A	339_V	0.774	1.00
96_A	99_N	0.772	1.00
167_S	250_M	0.768	1.00
100_H	103_K	0.766	1.00
167_S	252_K	0.765	1.00
293_T	311_K	0.763	1.00
67_D	72_E	0.763	1.00
202_D	362_S	0.758	1.00
340_E	345_L	0.758	1.00
340_E	348_H	0.758	1.00
114_G	117_L	0.758	1.00
228_M	361_S	0.757	1.00
232_L	239_F	0.757	1.00
308_C	341_H	0.755	1.00
301_M	326_Q	0.754	1.00
375_A	417_L	0.744	1.00
383_K	409_A	0.744	1.00
371_T	420_H	0.743	1.00
250_M	254_S	0.742	1.00
9_I	16_G	0.739	1.00
119_P	294_D	0.739	1.00
5_Y	8_V	0.738	1.00
217_L	228_M	0.736	1.00
307_S	346_N	0.735	1.00
19_A	338_A	0.733	1.00
61_R	65_E	0.732	1.00
385_G	463_A	0.731	1.00
183_S	256_D	0.731	1.00
64_R	75_G	0.728	1.00
177_M	274_K	0.727	1.00
148_I	338_A	0.723	1.00
208_T	272_A	0.723	1.00
407_I	463_A	0.722	1.00
47_C	51_K	0.718	1.00
302_I	317_A	0.714	1.00
65_E	399_G	0.713	1.00
120_S	143_I	0.711	1.00
167_S	257_I	0.710	1.00
186_I	193_G	0.710	1.00
286_E	291_E	0.709	1.00
137_E	140_D	0.708	1.00
310_T	317_A	0.707	1.00
156_R	159_P	0.707	1.00
435_L	441_A	0.705	1.00
419_V	437_K	0.705	1.00
72_E	75_G	0.704	1.00
246_L	267_T	0.704	1.00
298_E	303_S	0.700	1.00
151_T	288_I	0.696	1.00
55_R	58_E	0.696	1.00
220_E	359_I	0.694	1.00
211_E	218_P	0.693	1.00
290_L	293_T	0.693	1.00
435_L	449_T	0.693	1.00
308_C	337_I	0.693	1.00
263_K	266_E	0.693	1.00
415_D	442_T	0.692	1.00
56_S	69_F	0.692	1.00
163_V	168_V	0.690	1.00
66_A	69_F	0.690	1.00
353_T	378_N	0.688	1.00
168_V	250_M	0.684	1.00
199_M	203_F	0.683	1.00
89_A	92_D	0.682	1.00
37_K	45_K	0.682	1.00
295_I	315_I	0.681	1.00
409_A	443_P	0.680	1.00
97_G	101_L	0.680	1.00
34_E	37_K	0.678	1.00
77_S	80_F	0.676	1.00
385_G	409_A	0.676	1.00
334_E	352_P	0.675	1.00
433_A	437_K	0.673	1.00
392_I	395_A	0.673	1.00
160_G	245_V	0.672	1.00
197_A	209_V	0.671	1.00
301_M	323_G	0.671	1.00
119_P	293_T	0.671	1.00
24_A	107_I	0.671	1.00
285_I	321_V	0.670	1.00
250_M	255_D	0.670	1.00
443_P	447_G	0.670	1.00
98_V	101_L	0.669	1.00
85_Q	88_Q	0.668	1.00
50_S	196_W	0.666	1.00
158_L	162_E	0.664	1.00
88_Q	176_Q	0.663	1.00
193_G	212_Y	0.663	1.00
445_E	448_Q	0.663	1.00
428_D	457_S	0.661	1.00
257_I	275_M	0.659	1.00
304_V	308_C	0.659	1.00
423_G	426_V	0.658	1.00
435_L	446_V	0.657	0.99
194_I	216_I	0.656	0.99
389_F	459_A	0.656	0.99
333_H	336_I	0.656	0.99
63_A	71_V	0.655	0.99
240_I	261_A	0.653	0.99
214_D	222_L	0.653	0.99
243_A	266_E	0.653	0.99
197_A	237_I	0.652	0.99
435_L	439_L	0.652	0.99
153_S	281_R	0.652	0.99
416_I	437_K	0.651	0.99
84_Q	178_E	0.651	0.99
163_V	170_T	0.647	0.99
23_A	30_T	0.646	0.99
421_M	429_M	0.646	0.99
446_V	464_A	0.646	0.99
221_D	420_H	0.645	0.99
409_A	414_D	0.643	0.99
309_Q	312_E	0.641	0.99
413_T	440_D	0.638	0.99
212_Y	218_P	0.637	0.99
9_I	20_A	0.636	0.99
50_S	54_L	0.636	0.99
6_D	31_A	0.635	0.99
35_K	114_G	0.634	0.99
81_E	84_Q	0.633	0.99
24_A	30_T	0.632	0.99
87_K	176_Q	0.632	0.99
55_R	62_T	0.630	0.99
183_S	201_H	0.628	0.99
96_A	100_H	0.627	0.99
158_L	161_L	0.626	0.99
157_M	277_V	0.626	0.99
62_T	65_E	0.624	0.99
132_E	137_E	0.622	0.99
158_L	163_V	0.619	0.99
158_L	277_V	0.618	0.99
72_E	76_V	0.617	0.99
26_L	345_L	0.616	0.99
157_M	162_E	0.616	0.99
220_E	365_A	0.615	0.99
227_E	404_F	0.614	0.99
71_V	78_L	0.614	0.99
250_M	253_T	0.613	0.99
205_V	273_E	0.612	0.99
119_P	312_E	0.611	0.99
200_L	205_V	0.610	0.99
354_L	438_V	0.610	0.99
23_A	342_F	0.609	0.99
66_A	73_T	0.608	0.99
86_R	90_V	0.607	0.99
191_V	357_K	0.607	0.99
408_V	411_R	0.606	0.99
240_I	266_E	0.606	0.99
293_T	296_V	0.605	0.99
419_V	460_I	0.603	0.99
38_L	102_M	0.600	0.99
132_E	140_D	0.598	0.99
48_I	51_K	0.597	0.99
198_S	235_K	0.595	0.99
78_L	83_V	0.595	0.99
364_E	456_L	0.594	0.99
264_D	267_T	0.593	0.99
235_K	362_S	0.592	0.99
35_K	284_N	0.592	0.99
99_N	109_V	0.591	0.99
210_I	272_A	0.591	0.99
21_I	25_Q	0.589	0.99
58_E	362_S	0.587	0.99
370_L	380_H	0.586	0.99
86_R	89_A	0.585	0.99
198_S	232_L	0.585	0.99
453_H	458_E	0.585	0.99
161_L	164_D	0.584	0.99
194_I	239_F	0.584	0.99
382_V	417_L	0.583	0.99
344_G	347_P	0.582	0.99
37_K	95_A	0.582	0.99
36_E	172_D	0.582	0.99
90_V	94_L	0.581	0.99
25_Q	105_G	0.581	0.99
370_L	418_G	0.581	0.99
400_E	424_P	0.580	0.99
198_S	202_D	0.579	0.99
92_D	95_A	0.579	0.99
82_K	86_R	0.579	0.99
224_I	227_E	0.577	0.99
163_V	277_V	0.577	0.99
393_G	396_L	0.577	0.99
302_I	310_T	0.576	0.99
34_E	109_V	0.576	0.99
114_G	119_P	0.575	0.99
177_M	200_L	0.573	0.99
88_Q	91_V	0.573	0.99
57_A	60_Y	0.573	0.99
113_Y	118_G	0.572	0.99
296_V	300_G	0.571	0.99
323_G	326_Q	0.569	0.99
438_V	449_T	0.569	0.99
59_V	66_A	0.568	0.99
172_D	281_R	0.568	0.99
91_V	95_A	0.566	0.99
55_R	398_Y	0.563	0.98
330_V	334_E	0.563	0.98
159_P	164_D	0.563	0.98
296_V	302_I	0.561	0.98
193_G	278_S	0.560	0.98
87_K	90_V	0.559	0.98
148_I	339_V	0.559	0.98
318_I	335_G	0.558	0.98
434_G	438_V	0.558	0.98
113_Y	132_E	0.558	0.98
90_V	93_K	0.558	0.98
367_S	420_H	0.556	0.98
351_D	354_L	0.555	0.98
83_V	203_F	0.554	0.98
118_G	292_N	0.554	0.98
373_D	376_K	0.553	0.98
171_S	281_R	0.552	0.98
429_M	456_L	0.552	0.98
340_E	344_G	0.551	0.98
80_F	180_L	0.548	0.98
316_Y	342_F	0.548	0.98
155_P	171_S	0.547	0.98
63_A	76_V	0.547	0.98
59_V	63_A	0.546	0.98
444_W	448_Q	0.546	0.98
26_L	339_V	0.545	0.98
39_G	43_L	0.545	0.98
250_M	257_I	0.545	0.98
32_V	38_L	0.543	0.98
333_H	337_I	0.543	0.98
396_L	401_S	0.543	0.98
434_G	449_T	0.542	0.98
68_Q	399_G	0.542	0.98
15_G	150_A	0.540	0.98
382_V	411_R	0.539	0.98
208_T	270_Y	0.538	0.98
120_S	147_V	0.538	0.98
405_V	463_A	0.537	0.98
185_I	275_M	0.537	0.98
222_L	225_S	0.536	0.98
38_L	99_N	0.536	0.98
81_E	179_E	0.535	0.98
80_F	178_E	0.534	0.98
94_L	98_V	0.534	0.98
94_L	396_L	0.532	0.98
297_T	300_G	0.531	0.98
395_A	456_L	0.531	0.98
381_N	384_I	0.531	0.98
354_L	434_G	0.531	0.98
9_I	30_T	0.528	0.98
211_E	245_V	0.528	0.98
333_H	461_G	0.528	0.98
336_I	340_E	0.527	0.98
48_I	393_G	0.526	0.98
330_V	352_P	0.526	0.98
115_R	118_G	0.524	0.98
32_V	107_I	0.523	0.98
161_L	165_G	0.523	0.98
76_V	79_N	0.522	0.97
416_I	419_V	0.521	0.97
435_L	451_H	0.521	0.97
432_E	457_S	0.518	0.97
7_V	19_A	0.518	0.97
150_A	318_I	0.516	0.97
287_G	291_E	0.514	0.97
420_H	433_A	0.514	0.97
12_G	34_E	0.513	0.97
212_Y	279_I	0.513	0.97
184_I	207_V	0.513	0.97
193_G	218_P	0.513	0.97
165_G	250_M	0.512	0.97
362_S	400_E	0.511	0.97
33_V	110_Y	0.511	0.97
354_L	368_V	0.511	0.97
86_R	399_G	0.510	0.97
172_D	175_L	0.510	0.97
333_H	350_L	0.510	0.97
196_W	199_M	0.509	0.97
9_I	19_A	0.509	0.97
385_G	407_I	0.508	0.97
332_S	461_G	0.507	0.97
271_S	274_K	0.506	0.97
168_V	275_M	0.504	0.97
398_Y	456_L	0.504	0.97
389_F	405_V	0.502	0.97
185_I	257_I	0.502	0.97
196_W	276_L	0.501	0.97
110_Y	131_V	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ojtA	2	0.9747	100	0.202	Contact Map
3ladA	2	0.9726	100	0.209	Contact Map
1zmdA	4	0.9768	100	0.214	Contact Map
1lvlA	2	0.9578	100	0.22	Contact Map
1xdiA	3	0.9515	100	0.22	Contact Map
2a8xA	2	0.9705	100	0.221	Contact Map
3urhA	2	0.962	100	0.222	Contact Map
3ic9A	2	0.9662	100	0.223	Contact Map
2qaeA	2	0.9662	100	0.229	Contact Map
2eq6A	2	0.9557	100	0.231	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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