GREMLIN Database
YQII - Uncharacterized protein YqiI
UniProt: P54525 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 206 (179)
Sequences: 6510 (4799)
Seq/√Len: 358.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
64_T68_K2.9341.00
62_H190_Q2.9281.00
64_T76_A2.6581.00
34_I60_S2.5801.00
139_Q202_S2.5511.00
66_K194_D2.5241.00
31_T73_N2.5231.00
107_N117_E2.4891.00
59_V171_L2.4551.00
36_A60_S2.4161.00
136_I167_V2.3991.00
58_A189_Q2.2841.00
75_V96_N2.1491.00
51_F54_D2.1231.00
33_Y98_A2.0191.00
33_Y77_S1.9371.00
70_E201_D1.8131.00
56_N106_V1.7921.00
157_Y161_Y1.7421.00
50_L184_G1.7261.00
48_N180_A1.7251.00
118_T137_Q1.7221.00
88_E91_A1.7151.00
60_S104_I1.7131.00
85_T88_E1.6851.00
139_Q198_N1.6571.00
101_F158_V1.6231.00
58_A62_H1.6141.00
169_A196_I1.6011.00
137_Q148_D1.6001.00
94_S163_Q1.5821.00
53_K81_D1.5751.00
182_K188_Y1.5481.00
70_E197_V1.5371.00
33_Y92_K1.5341.00
109_G113_A1.5331.00
47_G180_A1.5301.00
66_K197_V1.5201.00
66_K190_Q1.5181.00
108_S175_T1.4991.00
55_I106_V1.4911.00
32_V72_A1.4781.00
60_S76_A1.4651.00
62_H186_E1.4291.00
90_V157_Y1.4181.00
50_L180_A1.4121.00
91_A95_A1.4091.00
93_A164_M1.3991.00
100_L132_L1.3831.00
75_V92_K1.3821.00
72_A201_D1.3431.00
130_R134_S1.3421.00
62_H189_Q1.3261.00
87_E157_Y1.3151.00
102_V200_I1.3141.00
62_H66_K1.3141.00
31_T75_V1.3141.00
63_V196_I1.3061.00
59_V106_V1.3031.00
45_A174_I1.2831.00
66_K70_E1.2781.00
135_D202_S1.2461.00
117_E152_K1.2451.00
29_G72_A1.2311.00
100_L200_I1.2241.00
117_E149_R1.2171.00
27_I72_A1.2171.00
139_Q142_S1.2161.00
185_S188_Y1.2141.00
120_F130_R1.1961.00
63_V197_V1.1871.00
135_D199_G1.1791.00
114_S178_S1.1731.00
30_K99_D1.1681.00
63_V193_A1.1641.00
30_K204_Y1.1591.00
106_V183_L1.1451.00
41_E83_F1.1431.00
68_K74_P1.1431.00
43_S51_F1.1311.00
92_K96_N1.1291.00
43_S46_V1.1261.00
104_I171_L1.1241.00
143_S195_A1.1181.00
57_L61_E1.1061.00
29_G73_N1.1031.00
87_E91_A1.0951.00
119_Y154_S1.0881.00
67_L197_V1.0821.00
98_A164_M1.0781.00
66_K69_E1.0611.00
64_T74_P1.0571.00
188_Y192_A1.0551.00
64_T79_S1.0431.00
34_I63_V1.0381.00
36_A77_S1.0351.00
35_D89_R1.0311.00
67_L72_A1.0291.00
114_S147_R1.0201.00
194_D198_N1.0181.00
137_Q141_V1.0101.00
93_A101_F1.0031.00
38_H105_H0.9981.00
180_A184_G0.9901.00
171_L196_I0.9821.00
190_Q194_D0.9811.00
46_V51_F0.9801.00
63_V104_I0.9791.00
171_L192_A0.9711.00
114_S182_K0.9701.00
62_H65_D0.9651.00
33_Y75_V0.9501.00
106_V174_I0.9441.00
50_L55_I0.9421.00
57_L78_R0.9371.00
131_R135_D0.9331.00
119_Y156_F0.9221.00
65_D68_K0.9181.00
172_G179_D0.9171.00
67_L200_I0.9131.00
134_S138_S0.9111.00
94_S164_M0.9071.00
62_H193_A0.9061.00
132_L167_V0.8961.00
155_D160_T0.8931.00
138_S202_S0.8871.00
29_G71_G0.8821.00
94_S162_S0.8801.00
65_D69_E0.8761.00
197_V201_D0.8731.00
128_N131_R0.8621.00
110_V175_T0.8561.00
139_Q195_A0.8511.00
61_E64_T0.8451.00
90_V161_Y0.8421.00
143_S198_N0.8411.00
90_V94_S0.8391.00
156_F168_L0.8361.00
177_S181_D0.8281.00
187_E191_K0.8241.00
38_H170_E0.8231.00
132_L203_Y0.8211.00
33_Y96_N0.8141.00
90_V162_S0.8091.00
116_T144_L0.8061.00
120_F133_A0.8041.00
178_S182_K0.8011.00
149_R173_F0.7871.00
86_L157_Y0.7811.00
111_A175_T0.7761.00
66_K193_A0.7721.00
93_A98_A0.7541.00
156_F159_I0.7481.00
116_T172_G0.7441.00
101_F166_S0.7391.00
39_G53_K0.7381.00
39_G42_D0.7371.00
174_I180_A0.7311.00
34_I64_T0.7301.00
133_A151_V0.7230.99
105_H170_E0.7180.99
27_I30_K0.7140.99
116_T140_L0.7120.99
59_V104_I0.7110.99
182_K191_K0.7090.99
149_R152_K0.7060.99
113_A175_T0.7050.99
118_T169_A0.7030.99
157_Y160_T0.7030.99
140_L195_A0.6970.99
144_L195_A0.6930.99
106_V171_L0.6920.99
31_T99_D0.6920.99
120_F153_E0.6910.99
119_Y152_K0.6890.99
32_V67_L0.6880.99
134_S151_V0.6860.99
42_D83_F0.6860.99
195_A199_G0.6860.99
141_V148_D0.6760.99
32_V100_L0.6760.99
102_V167_V0.6690.99
31_T96_N0.6670.99
116_T146_T0.6650.99
119_Y168_L0.6600.99
109_G175_T0.6550.99
198_N202_S0.6520.99
121_Q159_I0.6510.99
37_G170_E0.6490.99
100_L204_Y0.6480.99
35_D103_S0.6440.99
100_L203_Y0.6420.99
135_D139_Q0.6420.99
144_L172_G0.6420.99
178_S181_D0.6380.99
133_A167_V0.6360.99
40_G53_K0.6300.99
36_A76_A0.6300.99
70_E198_N0.6300.99
59_V193_A0.6290.99
88_E92_K0.6280.99
107_N173_F0.6280.99
67_L74_P0.6270.99
76_A79_S0.6250.99
140_L192_A0.6230.99
40_G78_R0.6160.98
172_G183_L0.6120.98
159_I166_S0.6100.98
139_Q143_S0.6080.98
140_L169_A0.6060.98
176_N179_D0.5990.98
118_T133_A0.5980.98
132_L136_I0.5960.98
84_L88_E0.5950.98
121_Q160_T0.5930.98
37_G105_H0.5930.98
59_V189_Q0.5920.98
61_E79_S0.5880.98
116_T137_Q0.5870.98
114_S179_D0.5870.98
135_D138_S0.5850.98
60_S63_V0.5850.98
50_L174_I0.5790.98
77_S92_K0.5700.97
53_K78_R0.5680.97
123_D126_G0.5670.97
88_E95_A0.5660.97
143_S191_K0.5650.97
120_F129_S0.5640.97
58_A186_E0.5630.97
115_G179_D0.5630.97
130_R153_E0.5610.97
116_T141_V0.5600.97
139_Q199_G0.5600.97
93_A162_S0.5600.97
45_A108_S0.5570.97
135_D203_Y0.5560.97
58_A61_E0.5550.97
146_T179_D0.5530.97
127_E130_R0.5520.97
118_T167_V0.5520.97
78_R81_D0.5510.97
117_E173_F0.5510.97
186_E189_Q0.5480.97
158_V168_L0.5470.97
34_I74_P0.5470.97
35_D77_S0.5470.97
119_Y173_F0.5450.97
198_N201_D0.5440.97
114_S176_N0.5430.96
54_D58_A0.5420.96
40_G81_D0.5420.96
57_L79_S0.5390.96
131_R134_S0.5370.96
68_K73_N0.5330.96
42_D53_K0.5300.96
111_A177_S0.5290.96
136_I196_I0.5280.96
120_F151_V0.5270.96
172_G188_Y0.5250.96
72_A204_Y0.5230.96
47_G55_I0.5190.95
154_S159_I0.5180.95
63_V200_I0.5110.95
118_T136_I0.5100.95
146_T172_G0.5070.95
158_V166_S0.5010.95
113_A173_F0.5000.94
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ne8A 2 0.8689 100 0.114 Contact Map
4rn7A 1 0.8641 100 0.115 Contact Map
1jwqA 1 0.8447 100 0.127 Contact Map
4binA 1 0.9612 100 0.131 Contact Map
4lq6A 1 0.8592 100 0.141 Contact Map
1xovA 1 0.8447 100 0.149 Contact Map
3czxA 2 0.8301 100 0.164 Contact Map
3qayA 1 0.8301 100 0.189 Contact Map
3nh4A 2 0.801 88.5 0.907 Contact Map
4axvA 2 0.8592 85.7 0.911 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0074 seconds.