GREMLIN Database
YQHY - Uncharacterized protein YqhY
UniProt: P54519 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 135 (113)
Sequences: 2065 (1181)
Seq/√Len: 111.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
76_D114_N5.1571.00
72_G109_S3.3771.00
79_C94_V2.6611.00
29_I105_M2.5141.00
75_I102_L2.4421.00
81_V87_I2.3871.00
72_G111_N2.2761.00
78_Y116_H2.1551.00
36_E97_N2.1521.00
110_I113_I2.1091.00
78_Y118_V2.0871.00
31_G60_H2.0681.00
74_T112_E2.0151.00
40_V94_V1.9841.00
69_A72_G1.9381.00
34_A43_M1.8581.00
30_A75_I1.8031.00
87_I117_I1.8021.00
99_R103_L1.7131.00
69_A74_T1.6501.00
41_A121_Q1.6481.00
77_V98_I1.6401.00
86_S89_K1.5471.00
71_D111_N1.5431.00
69_A111_N1.5341.00
27_E66_V1.5141.00
38_D85_V1.4911.00
64_V77_V1.4441.00
89_K93_S1.4261.00
81_V90_V1.4201.00
41_A122_F1.4141.00
43_M63_G1.4101.00
74_T111_N1.3431.00
93_S96_E1.3381.00
12_E15_H1.3291.00
38_D82_T1.3291.00
33_A101_T1.3281.00
85_V90_V1.3221.00
82_T123_D1.2910.99
44_R80_V1.2830.99
42_E80_V1.2830.99
80_V119_G1.2750.99
89_K92_A1.2650.99
67_D74_T1.2330.99
40_V79_C1.2300.99
17_G120_I1.1930.99
37_V95_Q1.1860.99
79_C117_I1.1810.99
103_L109_S1.1430.99
30_A102_L1.1380.99
30_A66_V1.1160.98
53_E62_K1.1090.98
34_A94_V1.1040.98
66_V75_I1.0830.98
94_V115_I1.0600.98
101_T105_M1.0440.97
103_L110_I1.0210.97
81_V85_V1.0200.97
14_T93_S1.0160.97
27_E61_G0.9970.97
95_Q99_R0.9830.96
42_E54_R0.9770.96
40_V65_K0.9680.96
26_I69_A0.9570.96
14_T124_T0.9550.96
38_D93_S0.9450.95
91_A117_I0.9440.95
26_I108_L0.9360.95
25_V29_I0.9170.95
22_A65_K0.9030.94
30_A110_I0.8940.94
17_G115_I0.8930.94
76_D116_H0.8910.94
36_E101_T0.8710.93
55_F96_E0.8680.93
21_I90_V0.8610.93
19_V103_L0.8590.92
23_P27_E0.8430.92
35_S40_V0.8090.90
35_S120_I0.7860.89
74_T114_N0.7710.88
23_P68_L0.7690.88
84_G87_I0.7670.87
34_A77_V0.7650.87
13_D18_K0.7520.86
25_V104_N0.7390.85
82_T85_V0.7390.85
26_I66_V0.7360.85
25_V105_M0.7360.85
69_A112_E0.7350.85
86_S91_A0.7320.85
98_I102_L0.6990.82
26_I73_I0.6990.82
29_I106_T0.6980.82
30_A34_A0.6870.81
14_T103_L0.6850.81
91_A116_H0.6800.80
97_N101_T0.6790.80
22_A25_V0.6730.80
39_G85_V0.6700.79
80_V121_Q0.6640.79
37_V97_N0.6570.78
24_E65_K0.6530.78
52_V107_S0.6520.77
21_I87_I0.6520.77
42_E98_I0.6480.77
79_C115_I0.6450.77
102_L110_I0.6440.77
100_Q104_N0.6430.77
53_E94_V0.6300.75
53_E120_I0.6260.75
52_V62_K0.6250.74
69_A117_I0.6240.74
92_A96_E0.6240.74
41_A54_R0.6240.74
43_M64_V0.6230.74
40_V77_V0.6190.74
40_V91_A0.6190.74
47_F56_G0.6180.74
31_G45_G0.6140.73
52_V102_L0.6130.73
102_L106_T0.6100.73
45_G53_E0.6090.73
73_I97_N0.6090.73
24_E120_I0.6080.72
107_S120_I0.6040.72
35_S42_E0.6010.72
16_L19_V0.5930.71
24_E59_N0.5910.70
88_P92_A0.5910.70
21_I30_A0.5900.70
20_E23_P0.5840.69
44_R50_G0.5830.69
68_L108_L0.5770.69
36_E104_N0.5750.68
77_V115_I0.5750.68
31_G59_N0.5720.68
51_V60_H0.5680.67
50_G55_F0.5570.66
31_G35_S0.5510.65
44_R119_G0.5490.65
61_G123_D0.5470.64
25_V94_V0.5460.64
71_D74_T0.5440.64
111_N124_T0.5430.64
31_G43_M0.5430.64
29_I38_D0.5410.64
31_G102_L0.5390.63
59_N87_I0.5340.63
51_V84_G0.5250.61
60_H102_L0.5230.61
92_A95_Q0.5220.61
29_I108_L0.5210.61
40_V64_V0.5200.61
86_S90_V0.5180.60
94_V113_I0.5170.60
32_I60_H0.5160.60
38_D100_Q0.5130.60
38_D88_P0.5120.59
21_I107_S0.5100.59
37_V121_Q0.5100.59
67_D73_I0.5080.59
79_C110_I0.5060.59
43_M118_V0.5060.59
68_L73_I0.5050.58
70_D111_N0.5030.58
91_A115_I0.5020.58
66_V73_I0.5020.58
89_K100_Q0.5020.58
17_G87_I0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4d2uA 3 0.5778 18.4 0.924 Contact Map
1wh9A 1 0.6593 12.8 0.929 Contact Map
4alzA 1 0.8 11.7 0.93 Contact Map
1qvrA 3 0.5852 5.9 0.939 Contact Map
4hvzA 5 0.5926 5.8 0.94 Contact Map
4hw9A 3 0.763 5.4 0.94 Contact Map
3zeyX 1 0.7407 4.2 0.943 Contact Map
3w61A 2 0.5704 4.1 0.944 Contact Map
4w23D 1 0.763 4 0.944 Contact Map
2f2hA 4 0.5111 3.8 0.945 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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