YQHT - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

YQHT - Uncharacterized peptidase YqhT

UniProt:	P54518	Sequences: MKLEKLRNLFGQLGIDGMLITSNTNVRYMTGFTGSAGLAVISGDKAAFITDFRYTEQAKVQVKGFEIIEHGGSLIQTTADTVESFGIKRLGFEQNSMTYGTYASYSAVISDAELVPVAESVEKLRLIKSSEEIKILEEAAKIADDAFRHILTFMKPGISEIAVANELEFYMRSQGADSSSFDMIVASGLRSSLPHGVASDKLIESGDLVTLDFGAYYKGYCSDITRTVAVGQPSDQLKEIYQVVFDAQALGVAHIKPGMTGKEADALTRDHIAAKGYGDYFGHSTGHGLGMEVHESPGLSVRSSAILEPGMVVTVEPGIYIPETGGVRIEDDIVITENGNRTITHSPKELIIL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	353 (335)
Sequences:	11018 (8025)
Seq/√Len:	438.5

ECOLI - YPDF AMPP PEPQ MAP1
BACSU - YQHT YKVY MAP11 MAP12
HALSA - Q9HRF6 Q9HQC0 Q9HMB3 Q9HP03
SULSO - Q981D7 Q980E9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
137_E	341_R	5.365	1.00
309_P	337_E	4.421	1.00
255_I	335_I	3.339	1.00
133_I	334_V	2.981	1.00
236_Q	324_T	2.704	1.00
242_Q	246_D	2.583	1.00
138_E	141_K	2.543	1.00
265_D	269_R	2.428	1.00
24_T	292_E	2.415	1.00
234_S	237_L	2.396	1.00
250_L	271_H	2.332	1.00
236_Q	239_E	2.328	1.00
145_D	174_Q	2.328	1.00
15_I	91_G	2.324	1.00
149_H	170_Y	2.323	1.00
189_L	201_K	2.314	1.00
262_K	304_S	2.304	1.00
260_T	263_E	2.261	1.00
166_E	169_F	2.257	1.00
169_F	173_S	2.255	1.00
235_D	239_E	2.197	1.00
136_L	312_V	2.189	1.00
289_L	332_D	2.171	1.00
127_I	308_E	2.159	1.00
249_A	253_A	2.149	1.00
270_D	274_A	2.144	1.00
103_A	106_S	2.135	1.00
159_S	202_L	2.121	1.00
30_T	39_A	2.081	1.00
89_R	113_E	2.078	1.00
254_H	267_L	2.052	1.00
137_E	141_K	2.021	1.00
243_V	275_K	2.007	1.00
135_I	218_K	1.914	1.00
203_I	230_V	1.897	1.00
251_G	268_T	1.884	1.00
250_L	253_A	1.865	1.00
49_I	81_T	1.826	1.00
240_I	325_G	1.814	1.00
204_E	207_D	1.812	1.00
153_F	166_E	1.800	1.00
240_I	327_V	1.774	1.00
201_K	207_D	1.756	1.00
161_I	200_D	1.745	1.00
168_E	172_R	1.743	1.00
244_V	327_V	1.728	1.00
212_D	223_D	1.721	1.00
266_A	270_D	1.692	1.00
223_D	330_E	1.687	1.00
336_T	341_R	1.684	1.00
77_T	80_D	1.677	1.00
208_L	237_L	1.667	1.00
238_K	242_Q	1.666	1.00
151_L	228_V	1.640	1.00
229_A	233_P	1.637	1.00
260_T	306_I	1.635	1.00
315_V	333_I	1.635	1.00
170_Y	173_S	1.624	1.00
185_V	209_V	1.620	1.00
170_Y	174_Q	1.595	1.00
271_H	275_K	1.581	1.00
212_D	330_E	1.565	1.00
308_E	311_M	1.550	1.00
314_T	332_D	1.544	1.00
144_D	346_S	1.540	1.00
65_F	68_I	1.539	1.00
246_D	250_L	1.533	1.00
159_S	162_A	1.529	1.00
246_D	275_K	1.521	1.00
165_N	169_F	1.514	1.00
156_P	205_S	1.507	1.00
180_S	221_C	1.498	1.00
89_R	115_V	1.488	1.00
252_V	333_I	1.476	1.00
334_V	343_I	1.472	1.00
272_I	319_I	1.467	1.00
256_K	259_M	1.457	1.00
148_R	152_T	1.454	1.00
38_L	41_I	1.443	1.00
126_L	311_M	1.436	1.00
187_S	201_K	1.426	1.00
149_H	174_Q	1.412	1.00
208_L	229_A	1.388	1.00
163_V	203_I	1.378	1.00
246_D	274_A	1.356	1.00
187_S	203_I	1.354	1.00
41_I	44_D	1.348	1.00
247_A	271_H	1.344	1.00
130_S	134_K	1.334	1.00
240_I	321_I	1.332	1.00
257_P	308_E	1.331	1.00
216_Y	221_C	1.326	1.00
245_F	249_A	1.325	1.00
322_P	325_G	1.318	1.00
16_D	88_K	1.314	1.00
27_R	219_G	1.312	1.00
149_H	152_T	1.310	1.00
134_K	138_E	1.309	1.00
259_M	263_E	1.301	1.00
166_E	170_Y	1.288	1.00
257_P	309_P	1.280	1.00
268_T	285_T	1.266	1.00
235_D	238_K	1.256	1.00
162_A	173_S	1.251	1.00
147_F	224_I	1.248	1.00
307_L	313_V	1.248	1.00
248_Q	331_D	1.245	1.00
29_M	124_L	1.243	1.00
11_G	43_G	1.232	1.00
51_D	54_Y	1.228	1.00
57_Q	61_Q	1.221	1.00
255_I	264_A	1.218	1.00
142_I	219_G	1.218	1.00
143_A	224_I	1.203	1.00
239_E	275_K	1.201	1.00
241_Y	329_I	1.199	1.00
123_K	308_E	1.198	1.00
15_I	115_V	1.195	1.00
127_I	311_M	1.184	1.00
263_E	266_A	1.177	1.00
136_L	140_A	1.167	1.00
252_V	342_T	1.167	1.00
250_L	267_L	1.164	1.00
190_R	196_G	1.164	1.00
102_Y	106_S	1.162	1.00
163_V	209_V	1.158	1.00
10_F	15_I	1.150	1.00
94_Q	103_A	1.150	1.00
164_A	168_E	1.142	1.00
55_T	59_K	1.141	1.00
307_L	335_I	1.141	1.00
149_H	173_S	1.140	1.00
255_I	315_V	1.134	1.00
246_D	271_H	1.131	1.00
239_E	243_V	1.131	1.00
142_I	176_A	1.123	1.00
138_E	217_Y	1.115	1.00
166_E	173_S	1.114	1.00
251_G	264_A	1.114	1.00
259_M	267_L	1.113	1.00
73_S	76_Q	1.113	1.00
141_K	145_D	1.109	1.00
149_H	166_E	1.105	1.00
208_L	227_T	1.101	1.00
25_N	93_E	1.100	1.00
134_K	137_E	1.096	1.00
255_I	333_I	1.089	1.00
186_A	196_G	1.087	1.00
262_K	266_A	1.085	1.00
239_E	242_Q	1.085	1.00
64_G	68_I	1.081	1.00
336_T	339_G	1.076	1.00
264_A	267_L	1.074	1.00
20_I	29_M	1.072	1.00
58_A	62_V	1.071	1.00
201_K	204_E	1.069	1.00
251_G	267_L	1.058	1.00
131_E	135_I	1.057	1.00
188_G	207_D	1.057	1.00
250_L	254_H	1.055	1.00
265_D	285_T	1.052	1.00
236_Q	321_I	1.049	1.00
333_I	342_T	1.046	1.00
64_G	67_I	1.045	1.00
312_V	334_V	1.045	1.00
140_A	144_D	1.036	1.00
10_F	17_G	1.035	1.00
168_E	183_M	1.035	1.00
137_E	334_V	1.032	1.00
16_D	89_R	1.028	1.00
25_N	122_E	1.023	1.00
99_Y	102_Y	1.021	1.00
270_D	273_A	1.020	1.00
254_H	259_M	1.018	1.00
257_P	336_T	1.017	1.00
262_K	302_R	1.015	1.00
310_G	334_V	1.014	1.00
79_A	83_E	1.011	1.00
247_A	272_I	1.010	1.00
313_V	335_I	0.999	1.00
243_V	272_I	0.999	1.00
99_Y	103_A	0.998	1.00
191_S	210_T	0.997	1.00
147_F	228_V	0.995	1.00
158_I	166_E	0.992	1.00
117_V	120_S	0.991	1.00
321_I	324_T	0.990	1.00
187_S	207_D	0.987	1.00
289_L	312_V	0.986	1.00
80_D	84_S	0.986	1.00
161_I	165_N	0.982	1.00
71_G	74_L	0.974	1.00
255_I	340_N	0.974	1.00
131_E	134_K	0.974	1.00
91_G	117_V	0.974	1.00
243_V	246_D	0.974	1.00
154_M	228_V	0.970	1.00
211_L	228_V	0.967	1.00
29_M	121_V	0.964	1.00
264_A	307_L	0.964	1.00
140_A	332_D	0.963	1.00
209_V	230_V	0.963	1.00
288_G	295_E	0.960	1.00
273_A	278_G	0.958	1.00
168_E	179_S	0.951	1.00
243_V	271_H	0.949	1.00
144_D	345_H	0.947	1.00
94_Q	116_P	0.944	1.00
190_R	201_K	0.927	1.00
123_K	305_A	0.924	1.00
179_S	183_M	0.919	1.00
81_T	84_S	0.917	1.00
267_L	270_D	0.917	1.00
20_I	121_V	0.915	1.00
190_R	193_L	0.914	1.00
176_A	215_A	0.913	1.00
155_K	158_I	0.908	1.00
146_A	170_Y	0.907	1.00
73_S	77_T	0.906	1.00
138_E	142_I	0.905	1.00
167_L	171_M	0.901	1.00
261_G	307_L	0.893	1.00
138_E	218_K	0.891	1.00
316_E	330_E	0.890	1.00
267_L	271_H	0.887	1.00
288_G	297_P	0.886	1.00
130_S	336_T	0.884	1.00
186_A	191_S	0.883	1.00
163_V	185_V	0.881	1.00
287_H	330_E	0.881	1.00
212_D	316_E	0.878	1.00
248_Q	251_G	0.877	1.00
223_D	287_H	0.876	1.00
154_M	163_V	0.870	1.00
242_Q	245_F	0.869	1.00
259_M	264_A	0.867	1.00
247_A	251_G	0.867	1.00
171_M	215_A	0.865	1.00
271_H	274_A	0.864	1.00
182_D	197_V	0.863	1.00
241_Y	245_F	0.861	1.00
252_V	340_N	0.861	1.00
145_D	148_R	0.861	1.00
305_A	308_E	0.856	1.00
229_A	237_L	0.856	1.00
18_M	117_V	0.856	1.00
272_I	277_Y	0.853	1.00
148_R	346_S	0.851	1.00
318_G	328_R	0.842	1.00
333_I	340_N	0.840	1.00
245_F	329_I	0.839	1.00
181_F	214_G	0.836	1.00
226_R	331_D	0.835	1.00
149_H	153_F	0.831	1.00
143_A	222_S	0.829	1.00
257_P	337_E	0.828	1.00
58_A	61_Q	0.824	1.00
335_I	340_N	0.822	1.00
248_Q	252_V	0.822	1.00
28_Y	124_L	0.821	1.00
334_V	341_R	0.821	1.00
320_Y	328_R	0.820	1.00
135_I	138_E	0.819	1.00
100_G	104_S	0.815	1.00
103_A	107_A	0.813	1.00
236_Q	240_I	0.812	1.00
81_T	85_F	0.812	1.00
41_I	46_A	0.810	1.00
80_D	83_E	0.807	1.00
140_A	344_T	0.807	1.00
156_P	230_V	0.805	1.00
158_I	162_A	0.805	1.00
268_T	281_F	0.800	1.00
132_E	220_Y	0.800	1.00
10_F	18_M	0.797	1.00
30_T	46_A	0.794	1.00
233_P	238_K	0.794	1.00
299_L	313_V	0.793	1.00
142_I	217_Y	0.790	1.00
47_A	66_E	0.790	1.00
92_F	99_Y	0.789	1.00
146_A	171_M	0.788	1.00
251_G	254_H	0.786	1.00
251_G	315_V	0.777	1.00
212_D	287_H	0.775	1.00
144_D	148_R	0.774	1.00
165_N	172_R	0.772	1.00
120_S	123_K	0.771	1.00
187_S	230_V	0.770	1.00
194_P	283_H	0.768	1.00
70_H	74_L	0.767	1.00
11_G	42_S	0.764	1.00
223_D	316_E	0.764	1.00
240_I	243_V	0.763	1.00
193_L	196_G	0.762	1.00
160_E	190_R	0.759	1.00
206_G	230_V	0.758	1.00
17_G	90_L	0.758	1.00
336_T	340_N	0.756	1.00
249_A	252_V	0.754	1.00
167_L	211_L	0.753	1.00
153_F	170_Y	0.751	1.00
98_T	101_T	0.751	1.00
48_F	58_A	0.747	1.00
221_C	293_V	0.747	1.00
252_V	315_V	0.746	1.00
247_A	267_L	0.745	1.00
195_H	294_H	0.744	1.00
60_V	63_K	0.744	1.00
191_S	208_L	0.743	1.00
27_R	291_M	0.738	1.00
257_P	335_I	0.736	1.00
140_A	222_S	0.731	1.00
225_T	330_E	0.728	1.00
269_R	281_F	0.727	1.00
289_L	314_T	0.726	1.00
167_L	213_F	0.725	1.00
260_T	304_S	0.724	1.00
150_I	211_L	0.722	1.00
303_S	306_I	0.721	1.00
126_L	308_E	0.719	1.00
256_K	340_N	0.717	1.00
162_A	165_N	0.713	1.00
263_E	267_L	0.702	1.00
42_S	46_A	0.702	1.00
215_A	222_S	0.701	1.00
135_I	217_Y	0.700	1.00
14_G	89_R	0.700	1.00
189_L	323_E	0.699	1.00
133_I	137_E	0.698	1.00
142_I	174_Q	0.693	1.00
74_L	82_V	0.692	1.00
179_S	182_D	0.689	1.00
283_H	294_H	0.686	1.00
240_I	277_Y	0.685	1.00
305_A	311_M	0.683	1.00
208_L	233_P	0.681	1.00
87_I	90_L	0.681	1.00
287_H	316_E	0.680	1.00
140_A	343_I	0.678	1.00
306_I	309_P	0.678	1.00
169_F	172_R	0.677	1.00
104_S	107_A	0.677	1.00
74_L	77_T	0.676	1.00
206_G	232_Q	0.674	1.00
147_F	213_F	0.672	1.00
47_A	81_T	0.671	1.00
191_S	326_G	0.668	1.00
88_K	113_E	0.666	1.00
141_K	144_D	0.665	1.00
150_I	163_V	0.665	1.00
233_P	237_L	0.662	1.00
23_N	26_V	0.661	1.00
254_H	257_P	0.660	1.00
128_K	132_E	0.660	1.00
126_L	305_A	0.660	1.00
45_K	71_G	0.658	1.00
45_K	66_E	0.656	1.00
257_P	340_N	0.655	1.00
248_Q	315_V	0.655	1.00
147_F	150_I	0.647	0.99
298_G	302_R	0.646	0.99
251_G	285_T	0.646	0.99
142_I	215_A	0.646	0.99
253_A	264_A	0.645	0.99
243_V	319_I	0.645	0.99
143_A	146_A	0.644	0.99
312_V	332_D	0.644	0.99
246_D	249_A	0.643	0.99
255_I	307_L	0.641	0.99
59_K	62_V	0.641	0.99
152_T	156_P	0.640	0.99
130_S	310_G	0.638	0.99
205_S	232_Q	0.638	0.99
207_D	237_L	0.634	0.99
164_A	198_A	0.634	0.99
134_K	141_K	0.633	0.99
32_F	57_Q	0.633	0.99
320_Y	326_G	0.632	0.99
25_N	121_V	0.632	0.99
159_S	200_D	0.632	0.99
24_T	291_M	0.632	0.99
318_G	326_G	0.631	0.99
154_M	230_V	0.630	0.99
71_G	75_I	0.628	0.99
154_M	209_V	0.624	0.99
229_A	234_S	0.623	0.99
185_V	211_L	0.623	0.99
212_D	225_T	0.620	0.99
237_L	324_T	0.620	0.99
191_S	229_A	0.619	0.99
21_T	24_T	0.616	0.99
133_I	312_V	0.614	0.99
257_P	339_G	0.614	0.99
309_P	336_T	0.614	0.99
92_F	114_L	0.612	0.99
73_S	81_T	0.609	0.99
58_A	63_K	0.609	0.99
140_A	224_I	0.609	0.99
26_V	37_G	0.603	0.99
77_T	81_T	0.602	0.99
280_Y	322_P	0.601	0.99
264_A	285_T	0.601	0.99
261_G	299_L	0.601	0.99
110_S	114_L	0.601	0.99
45_K	64_G	0.600	0.99
150_I	166_E	0.599	0.99
97_M	102_Y	0.597	0.99
147_F	151_L	0.596	0.99
143_A	213_F	0.596	0.99
256_K	338_N	0.596	0.99
19_L	90_L	0.596	0.99
232_Q	238_K	0.594	0.99
146_A	167_L	0.594	0.99
16_D	42_S	0.593	0.99
13_L	16_D	0.593	0.99
321_I	325_G	0.592	0.99
247_A	268_T	0.590	0.99
224_I	332_D	0.589	0.99
139_A	143_A	0.584	0.99
158_I	163_V	0.579	0.99
243_V	247_A	0.579	0.99
191_S	194_P	0.577	0.99
266_A	301_V	0.575	0.99
253_A	267_L	0.575	0.99
237_L	325_G	0.572	0.99
150_I	153_F	0.570	0.99
342_T	345_H	0.570	0.99
250_L	268_T	0.566	0.99
130_S	309_P	0.565	0.99
26_V	30_T	0.564	0.99
281_F	285_T	0.564	0.99
10_F	13_L	0.563	0.99
284_S	287_H	0.562	0.99
163_V	211_L	0.561	0.98
189_L	192_S	0.559	0.98
128_K	220_Y	0.559	0.98
19_L	40_V	0.559	0.98
122_E	296_S	0.555	0.98
71_G	82_V	0.555	0.98
25_N	28_Y	0.554	0.98
52_F	282_G	0.554	0.98
262_K	303_S	0.552	0.98
258_G	306_I	0.552	0.98
17_G	42_S	0.552	0.98
183_M	213_F	0.552	0.98
247_A	250_L	0.552	0.98
332_D	344_T	0.551	0.98
146_A	215_A	0.549	0.98
259_M	335_I	0.548	0.98
162_A	202_L	0.545	0.98
151_L	346_S	0.542	0.98
143_A	214_G	0.542	0.98
90_L	112_A	0.542	0.98
316_E	328_R	0.540	0.98
144_D	344_T	0.539	0.98
205_S	231_G	0.539	0.98
59_K	63_K	0.536	0.98
123_K	126_L	0.535	0.98
236_Q	325_G	0.534	0.98
127_I	309_P	0.534	0.98
261_G	303_S	0.533	0.98
254_H	264_A	0.533	0.98
50_T	55_T	0.532	0.98
98_T	102_Y	0.532	0.98
76_Q	79_A	0.531	0.98
265_D	281_F	0.530	0.98
258_G	308_E	0.529	0.98
54_Y	57_Q	0.528	0.98
24_T	125_R	0.527	0.98
243_V	277_Y	0.526	0.98
140_A	143_A	0.525	0.98
234_S	324_T	0.525	0.98
186_A	209_V	0.525	0.98
27_R	33_T	0.524	0.98
248_Q	329_I	0.523	0.98
272_I	278_G	0.523	0.98
47_A	73_S	0.522	0.98
20_I	26_V	0.522	0.98
294_H	328_R	0.522	0.98
221_C	291_M	0.519	0.98
294_H	318_G	0.514	0.97
26_V	39_A	0.514	0.97
265_D	284_S	0.514	0.97
47_A	85_F	0.513	0.97
266_A	273_A	0.511	0.97
283_H	320_Y	0.511	0.97
161_I	177_D	0.509	0.97
171_M	176_A	0.507	0.97
240_I	319_I	0.506	0.97
264_A	299_L	0.506	0.97
284_S	298_G	0.506	0.97
341_R	345_H	0.506	0.97
190_R	200_D	0.505	0.97
92_F	102_Y	0.505	0.97
39_A	46_A	0.504	0.97
195_H	283_H	0.502	0.97
283_H	328_R	0.502	0.97
268_T	271_H	0.502	0.97
138_E	219_G	0.501	0.97
17_G	40_V	0.500	0.97
223_D	294_H	0.500	0.97

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3q6dA	1	0.9972	100	0.124	Contact Map
2zsgA	2	0.9972	100	0.125	Contact Map
4fkcA	2	0.9972	100	0.126	Contact Map
1wn1A	2	0.9858	100	0.144	Contact Map
4r60A	2	0.9943	100	0.149	Contact Map
1wy2A	2	0.9717	100	0.159	Contact Map
4egeA	2	0.9887	100	0.163	Contact Map
1kp0A	2	0.8895	100	0.186	Contact Map
3ig4A	4	0.9915	100	0.186	Contact Map
1chmA	2	0.9915	100	0.19	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0106 seconds.