LIPM - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

LIPM - Octanoyltransferase LipM

UniProt:	P54511	Sequences: MQKETWRFIDSGNASPAFNMALDEALLYWHSEKKIPPVIRFYGWNPATLSVGYFQNIKKEINFEAVHKYNLGFVRRPTGGRGVLHDQELTYSVIVSEEHPEMPATVTEAYRVISEGILQGFRNLGLDAYFAIPRTEKEKESLKNPRSSVCFDAPSWYELVVEGRKVAGSAQTRQKGVILQHGSILLDLDEDKLFDLFLYPSERVRERMQRNFKNKAVAINELIEKRVTMDEARKAFKEGFETGLNIHLEPYELSQEELDFVHHLAETKYASDEWNYKR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	278 (236)
Sequences:	2516 (1731)
Seq/√Len:	112.7

ECOLI - LPLA
BACSU - LIPM LPLJ LIPL
HALSA - Q9HSK8 Q9HMH8 Q9HHS2
SULSO - Q97U65 Q97U62 Q97Z28 Q97Z70

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
263_H	267_T	4.065	1.00
187_D	220_N	3.877	1.00
217_V	222_L	3.388	1.00
24_E	28_Y	2.898	1.00
66_V	73_F	2.836	1.00
115_E	119_Q	2.731	1.00
65_A	69_Y	2.658	1.00
122_R	127_D	2.594	1.00
69_Y	196_L	2.552	1.00
228_T	231_E	2.409	1.00
123_N	242_T	2.340	1.00
64_E	68_K	2.299	1.00
254_S	257_E	2.217	1.00
123_N	239_G	2.135	1.00
24_E	268_K	2.128	1.00
42_Y	92_S	2.119	1.00
260_F	263_H	2.106	1.00
265_A	270_A	2.022	1.00
119_Q	242_T	2.008	1.00
91_Y	182_G	1.996	1.00
264_L	269_Y	1.986	1.00
159_L	166_V	1.890	1.00
189_D	192_K	1.859	1.00
85_H	90_T	1.844	1.00
262_H	266_E	1.833	1.00
127_D	162_E	1.801	1.00
74_V	275_N	1.766	1.00
217_V	221_E	1.749	1.00
78_T	172_T	1.731	1.00
65_A	68_K	1.721	1.00
119_Q	122_R	1.709	1.00
69_Y	195_D	1.699	1.00
89_L	229_M	1.688	1.00
28_Y	260_F	1.679	1.00
264_L	268_K	1.667	1.00
15_S	18_F	1.657	1.00
204_V	208_M	1.654	1.00
124_L	235_A	1.639	1.00
49_L	66_V	1.624	1.00
119_Q	239_G	1.624	1.00
28_Y	174_Q	1.623	1.00
51_V	57_I	1.597	1.00
24_E	269_Y	1.595	1.00
46_P	72_G	1.585	1.00
18_F	258_L	1.584	1.00
10_D	233_R	1.568	1.00
85_H	88_E	1.566	1.00
29_W	260_F	1.550	1.00
257_E	260_F	1.521	1.00
65_A	196_L	1.518	1.00
97_E	176_G	1.504	1.00
23_D	181_H	1.497	1.00
63_F	67_H	1.493	1.00
63_F	73_F	1.486	1.00
225_K	231_E	1.484	1.00
167_A	183_S	1.479	1.00
201_S	205_R	1.465	1.00
157_Y	203_R	1.460	1.00
120_G	239_G	1.454	1.00
208_M	211_N	1.435	1.00
256_E	259_D	1.434	1.00
50_S	85_H	1.431	1.00
234_K	238_E	1.429	1.00
164_R	217_V	1.419	1.00
161_V	166_V	1.415	1.00
39_I	240_F	1.403	1.00
266_E	270_A	1.390	1.00
166_V	219_I	1.389	1.00
25_A	29_W	1.387	1.00
89_L	232_A	1.372	1.00
170_A	181_H	1.347	1.00
26_L	38_V	1.344	1.00
204_V	209_Q	1.337	1.00
69_Y	192_K	1.335	1.00
19_N	45_N	1.330	1.00
37_P	96_S	1.329	1.00
20_M	23_D	1.300	0.99
45_N	85_H	1.299	0.99
186_L	232_A	1.289	0.99
251_Y	257_E	1.287	0.99
164_R	221_E	1.277	0.99
111_R	115_E	1.271	0.99
82_G	197_F	1.238	0.99
18_F	22_L	1.222	0.99
157_Y	215_K	1.210	0.99
253_L	261_V	1.208	0.99
88_E	183_S	1.196	0.99
161_V	222_L	1.194	0.99
20_M	50_S	1.190	0.99
123_N	235_A	1.185	0.99
62_N	198_L	1.184	0.99
195_D	198_L	1.183	0.99
19_N	85_H	1.171	0.99
230_D	234_K	1.168	0.99
128_A	161_V	1.167	0.99
16_P	74_V	1.131	0.99
42_Y	180_Q	1.117	0.98
118_L	128_A	1.114	0.98
167_A	182_G	1.109	0.98
203_R	215_K	1.099	0.98
55_Q	60_E	1.099	0.98
272_D	275_N	1.097	0.98
237_K	241_E	1.096	0.98
89_L	233_R	1.096	0.98
50_S	83_V	1.095	0.98
65_A	71_L	1.082	0.98
123_N	238_E	1.074	0.98
193_L	216_A	1.067	0.98
263_H	266_E	1.065	0.98
57_I	276_Y	1.059	0.98
8_F	237_K	1.052	0.98
192_K	195_D	1.048	0.98
160_V	163_G	1.046	0.98
42_Y	50_S	1.044	0.98
169_S	180_Q	1.040	0.97
169_S	182_G	1.038	0.97
77_P	268_K	1.038	0.97
71_L	196_L	1.033	0.97
120_G	236_F	1.032	0.97
131_A	160_V	1.029	0.97
258_L	262_H	1.024	0.97
121_F	232_A	1.021	0.97
20_M	85_H	1.020	0.97
45_N	88_E	1.017	0.97
85_H	181_H	1.016	0.97
43_G	229_M	1.014	0.97
128_A	131_A	1.012	0.97
61_I	66_V	1.012	0.97
155_S	158_E	1.008	0.97
64_E	67_H	1.006	0.97
22_L	261_V	1.003	0.97
220_N	226_R	1.002	0.97
30_H	96_S	0.997	0.97
204_V	207_R	0.995	0.97
206_E	210_R	0.993	0.97
51_V	82_G	0.984	0.96
81_R	167_A	0.979	0.96
256_E	260_F	0.978	0.96
209_Q	212_F	0.977	0.96
199_Y	203_R	0.975	0.96
50_S	88_E	0.965	0.96
78_T	181_H	0.963	0.96
66_V	71_L	0.963	0.96
23_D	40_R	0.958	0.96
26_L	30_H	0.948	0.96
20_M	88_E	0.946	0.96
171_Q	180_Q	0.944	0.96
86_D	192_K	0.936	0.95
25_A	261_V	0.929	0.95
191_D	213_K	0.918	0.95
111_R	130_F	0.904	0.94
77_P	269_Y	0.904	0.94
203_R	207_R	0.902	0.94
208_M	212_F	0.900	0.94
77_P	172_T	0.899	0.94
65_A	195_D	0.898	0.94
239_G	242_T	0.887	0.94
190_E	218_A	0.885	0.94
120_G	235_A	0.884	0.94
62_N	65_A	0.872	0.93
259_D	263_H	0.867	0.93
113_I	116_G	0.865	0.93
43_G	233_R	0.860	0.93
118_L	159_L	0.855	0.93
83_V	90_T	0.854	0.92
114_S	169_S	0.852	0.92
84_L	196_L	0.851	0.92
15_S	72_G	0.848	0.92
50_S	180_Q	0.844	0.92
262_H	265_A	0.840	0.92
97_E	173_R	0.836	0.92
50_S	90_T	0.835	0.92
20_M	90_T	0.832	0.91
41_F	233_R	0.832	0.91
57_I	63_F	0.830	0.91
259_D	262_H	0.829	0.91
239_G	243_G	0.827	0.91
265_A	271_S	0.826	0.91
92_S	180_Q	0.825	0.91
97_E	178_I	0.824	0.91
273_E	276_Y	0.822	0.91
128_A	159_L	0.821	0.91
10_D	237_K	0.820	0.91
190_E	194_F	0.820	0.91
59_K	206_E	0.820	0.91
189_D	218_A	0.818	0.91
185_L	188_L	0.814	0.91
35_I	38_V	0.811	0.90
251_Y	254_S	0.809	0.90
121_F	166_V	0.798	0.90
186_L	229_M	0.782	0.89
190_E	193_L	0.780	0.89
131_A	155_S	0.780	0.89
241_E	248_L	0.779	0.89
49_L	197_F	0.776	0.88
48_T	72_G	0.775	0.88
92_S	181_H	0.775	0.88
227_V	235_A	0.774	0.88
47_A	192_K	0.769	0.88
61_I	73_F	0.768	0.88
30_H	36_P	0.765	0.88
95_V	178_I	0.761	0.87
50_S	183_S	0.761	0.87
26_L	37_P	0.750	0.87
235_A	238_E	0.748	0.86
83_V	183_S	0.744	0.86
166_V	217_V	0.744	0.86
15_S	270_A	0.742	0.86
119_Q	243_G	0.740	0.86
110_Y	171_Q	0.737	0.86
60_E	211_N	0.734	0.85
255_Q	259_D	0.733	0.85
191_D	194_F	0.732	0.85
92_S	170_A	0.731	0.85
87_Q	187_D	0.731	0.85
232_A	236_F	0.730	0.85
206_E	211_N	0.724	0.85
155_S	215_K	0.723	0.85
83_V	88_E	0.722	0.85
87_Q	218_A	0.719	0.84
157_Y	207_R	0.719	0.84
204_V	211_N	0.712	0.84
162_E	222_L	0.707	0.83
186_L	227_V	0.705	0.83
79_G	168_G	0.704	0.83
92_S	179_L	0.701	0.83
110_Y	113_I	0.700	0.83
81_R	158_E	0.694	0.82
60_E	185_L	0.693	0.82
22_L	253_L	0.691	0.82
65_A	192_K	0.687	0.81
59_K	210_R	0.687	0.81
192_K	196_L	0.686	0.81
261_V	264_L	0.685	0.81
253_L	258_L	0.681	0.81
114_S	159_L	0.681	0.81
155_S	203_R	0.675	0.80
18_F	265_A	0.671	0.80
37_P	95_V	0.670	0.80
211_N	214_N	0.669	0.80
185_L	218_A	0.664	0.79
27_L	174_Q	0.662	0.79
19_N	182_G	0.657	0.79
117_I	236_F	0.655	0.78
38_V	257_E	0.651	0.78
8_F	248_L	0.644	0.77
81_R	183_S	0.643	0.77
229_M	233_R	0.641	0.77
45_N	90_T	0.640	0.77
68_K	259_D	0.640	0.77
92_S	171_Q	0.640	0.77
209_Q	215_K	0.639	0.77
59_K	204_V	0.639	0.77
169_S	172_T	0.636	0.76
26_L	94_I	0.636	0.76
16_P	275_N	0.634	0.76
259_D	266_E	0.631	0.76
157_Y	199_Y	0.631	0.76
234_K	249_E	0.630	0.76
169_S	181_H	0.629	0.75
167_A	185_L	0.628	0.75
81_R	216_A	0.627	0.75
109_A	173_R	0.626	0.75
57_I	275_N	0.624	0.75
58_K	272_D	0.624	0.75
20_M	269_Y	0.621	0.75
48_T	85_H	0.621	0.75
158_E	216_A	0.617	0.74
241_E	247_H	0.616	0.74
207_R	210_R	0.609	0.73
159_L	167_A	0.609	0.73
110_Y	156_W	0.608	0.73
218_A	222_L	0.604	0.73
173_R	178_I	0.603	0.72
94_I	179_L	0.602	0.72
36_P	96_S	0.601	0.72
186_L	220_N	0.598	0.72
208_M	215_K	0.597	0.72
67_H	272_D	0.594	0.71
261_V	265_A	0.593	0.71
85_H	188_L	0.591	0.71
91_Y	155_S	0.590	0.71
156_W	197_F	0.589	0.71
255_Q	260_F	0.589	0.71
91_Y	180_Q	0.586	0.70
11_S	253_L	0.585	0.70
171_Q	178_I	0.585	0.70
42_Y	88_E	0.584	0.70
159_L	178_I	0.584	0.70
251_Y	261_V	0.582	0.70
30_H	35_I	0.580	0.69
128_A	166_V	0.580	0.69
260_F	266_E	0.580	0.69
85_H	182_G	0.578	0.69
98_E	259_D	0.578	0.69
28_Y	32_E	0.576	0.69
158_E	203_R	0.576	0.69
42_Y	186_L	0.575	0.69
81_R	157_Y	0.574	0.69
63_F	276_Y	0.572	0.68
158_E	167_A	0.569	0.68
49_L	244_L	0.568	0.68
52_G	158_E	0.565	0.67
123_N	231_E	0.564	0.67
122_R	128_A	0.563	0.67
93_V	113_I	0.559	0.67
11_S	22_L	0.556	0.66
90_T	169_S	0.554	0.66
204_V	210_R	0.552	0.66
62_N	68_K	0.551	0.66
231_E	234_K	0.549	0.65
77_P	82_G	0.549	0.65
84_L	192_K	0.547	0.65
60_E	197_F	0.546	0.65
42_Y	90_T	0.545	0.65
16_P	20_M	0.545	0.65
96_S	177_V	0.544	0.65
219_I	232_A	0.543	0.64
190_E	221_E	0.543	0.64
272_D	276_Y	0.542	0.64
42_Y	169_S	0.541	0.64
253_L	257_E	0.540	0.64
87_Q	188_L	0.538	0.64
129_Y	163_G	0.537	0.64
269_Y	275_N	0.536	0.63
77_P	179_L	0.533	0.63
67_H	250_P	0.529	0.62
27_L	172_T	0.528	0.62
217_V	220_N	0.528	0.62
183_S	216_A	0.528	0.62
50_S	78_T	0.528	0.62
40_R	113_I	0.528	0.62
93_V	160_V	0.524	0.62
75_R	81_R	0.522	0.61
11_S	40_R	0.520	0.61
82_G	121_F	0.518	0.61
24_E	172_T	0.518	0.61
41_F	92_S	0.518	0.61
18_F	262_H	0.518	0.61
255_Q	258_L	0.518	0.61
27_L	179_L	0.518	0.61
10_D	43_G	0.515	0.60
27_L	31_S	0.514	0.60
256_E	267_T	0.513	0.60
260_F	264_L	0.512	0.60
127_D	222_L	0.512	0.60
57_I	90_T	0.512	0.60
81_R	84_L	0.511	0.60
41_F	120_G	0.510	0.60
63_F	66_V	0.508	0.59
51_V	73_F	0.507	0.59
22_L	40_R	0.502	0.58
98_E	176_G	0.501	0.58
17_A	275_N	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3a7rA	1	0.8633	100	0.252	Contact Map
2c8mA	1	0.8705	100	0.273	Contact Map
2e5aA	1	0.8561	100	0.283	Contact Map
1vqzA	1	0.8705	100	0.314	Contact Map
2p0lA	1	0.8921	100	0.37	Contact Map
2p5iA	1	0.8885	100	0.385	Contact Map
2qhsA	1	0.7446	100	0.466	Contact Map
1w66A	1	0.7374	100	0.498	Contact Map
2dxuA	2	0.6619	97.9	0.885	Contact Map
2eayA	2	0.6259	97.6	0.893	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0088 seconds.