GREMLIN Database
YQGV - UPF0045 protein YqgV
UniProt: P54499 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 104 (96)
Sequences: 534 (355)
Seq/√Len: 36.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
89_T93_S3.6711.00
96_E100_K3.1621.00
43_T48_L2.9181.00
54_S61_Q2.8771.00
39_K92_E2.4311.00
60_I79_I2.1840.99
44_P91_L2.1460.99
76_A80_R2.0440.99
4_A60_I2.0090.98
90_T93_S1.8870.98
38_I49_I1.8730.98
45_M82_D1.8390.97
19_S101_H1.8350.97
68_F85_R1.7930.97
28_I66_A1.7900.97
64_H77_T1.7290.96
6_V60_I1.7100.96
97_S101_H1.6720.95
5_D80_R1.6510.95
9_I76_A1.6430.95
92_E96_E1.6340.95
6_V63_I1.4680.91
27_K102_L1.4680.91
6_V49_I1.4570.90
41_Q92_E1.4400.90
26_Q40_Y1.4360.90
13_T16_P1.4070.89
55_D58_A1.4030.89
57_F81_I1.3940.88
31_G62_A1.3690.87
4_A56_L1.3120.85
68_F83_D1.3110.85
25_V63_I1.2620.83
29_L59_V1.2580.82
3_I91_L1.2200.80
96_E99_N1.1130.74
77_T81_I1.1070.74
37_K55_D1.0960.73
53_L56_L1.0830.72
69_Q79_I1.0600.70
38_I56_L1.0580.70
24_D70_K1.0430.69
26_Q42_L1.0330.68
25_V67_P1.0320.68
52_E61_Q1.0310.68
8_I25_V1.0220.67
58_A62_A1.0170.67
44_P48_L0.9660.63
43_T82_D0.9650.63
67_P97_S0.9600.62
42_L98_V0.9590.62
19_S97_S0.9440.61
24_D27_K0.9390.61
9_I29_L0.9320.60
9_I77_T0.9160.59
36_G59_V0.9120.58
58_A61_Q0.9100.58
22_V87_K0.9080.58
30_E102_L0.8910.57
9_I78_N0.8760.55
28_I63_I0.8610.54
21_Y72_L0.8600.54
2_A51_G0.8510.53
68_F82_D0.8470.53
9_I22_V0.8390.52
5_D48_L0.8260.51
45_M48_L0.8210.51
54_S81_I0.8160.50
45_M94_K0.8140.50
64_H83_D0.8090.50
30_E99_N0.8080.49
31_G70_K0.7960.48
24_D54_S0.7960.48
57_F60_I0.7920.48
14_E51_G0.7830.47
3_I79_I0.7750.47
7_T94_K0.7670.46
88_K100_K0.7660.46
71_G86_D0.7630.46
12_G17_S0.7420.44
43_T46_N0.7180.42
4_A49_I0.7170.42
28_I88_K0.7160.41
52_E55_D0.7120.41
30_E40_Y0.7090.41
11_I76_A0.7080.41
68_F75_V0.7050.41
45_M85_R0.7030.40
28_I62_A0.7000.40
86_D90_T0.7000.40
14_E72_L0.6970.40
53_L57_F0.6950.40
6_V80_R0.6920.39
27_K31_G0.6910.39
40_Y59_V0.6860.39
16_P73_H0.6840.39
62_A66_A0.6770.38
20_A101_H0.6740.38
5_D26_Q0.6680.37
28_I51_G0.6630.37
9_I12_G0.6630.37
48_L82_D0.6610.37
23_A94_K0.6580.37
4_A44_P0.6570.37
46_N49_I0.6520.36
69_Q92_E0.6460.36
13_T49_I0.6460.36
18_V94_K0.6450.36
6_V79_I0.6350.35
39_K50_E0.6240.34
75_V85_R0.6180.34
13_T71_G0.6150.33
75_V83_D0.6080.33
43_T67_P0.6050.32
19_S91_L0.6050.32
69_Q95_I0.6000.32
3_I22_V0.5980.32
67_P72_L0.5910.31
5_D46_N0.5830.31
54_S58_A0.5810.31
23_A97_S0.5750.30
25_V77_T0.5740.30
22_V70_K0.5730.30
39_K86_D0.5630.29
36_G55_D0.5620.29
2_A54_S0.5600.29
7_T45_M0.5580.29
26_Q29_L0.5520.29
18_V82_D0.5520.29
11_I59_V0.5520.29
30_E88_K0.5510.29
80_R94_K0.5500.28
40_Y81_I0.5500.28
2_A56_L0.5450.28
12_G48_L0.5430.28
6_V29_L0.5420.28
13_T24_D0.5320.27
71_G83_D0.5210.26
56_L63_I0.5090.26
11_I19_S0.5060.25
59_V66_A0.5060.25
25_V66_A0.5050.25
18_V45_M0.5030.25
20_A70_K0.5000.25
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1lxjA 4 0.9615 100 0.221 Contact Map
1lxnA 4 0.9423 100 0.223 Contact Map
1yqhA 3 0.9423 100 0.261 Contact Map
2epiA 4 0.9135 100 0.274 Contact Map
1vk8A 4 0.8846 100 0.277 Contact Map
2iboA 4 0.8558 100 0.308 Contact Map
1s99A 2 0.8077 99.8 0.564 Contact Map
1knvA 4 0.9423 27.9 0.926 Contact Map
3tc3A 1 0.9423 24.4 0.929 Contact Map
3c1mA 3 0.6346 22.7 0.929 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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