GREMLIN Database
YQGT - Uncharacterized protein YqgT
UniProt: P54497 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 376 (329)
Sequences: 2093 (1328)
Seq/√Len: 73.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
135_A148_L5.7111.00
160_C171_I5.0981.00
203_R229_L4.1441.00
259_L268_Y3.6031.00
136_S145_T3.5011.00
117_I266_A3.4381.00
86_D90_E3.3341.00
112_V206_E3.1531.00
107_E116_P2.9191.00
234_P259_L2.8851.00
110_R116_P2.8681.00
115_R191_D2.8621.00
134_N281_A2.7921.00
94_K118_W2.6381.00
63_K67_Q2.6351.00
180_S270_L2.5351.00
236_L239_I2.4761.00
148_L282_L2.4141.00
224_I249_S2.2001.00
305_I318_G2.1871.00
94_K105_C2.1851.00
135_A144_T2.1541.00
61_D64_R2.1501.00
262_P266_A2.1441.00
122_A152_F2.1361.00
238_E254_P2.1101.00
303_A370_R2.0941.00
312_S362_N2.0931.00
283_H344_E2.0821.00
235_S334_H2.0521.00
80_Q149_L2.0491.00
117_I182_V2.0391.00
109_G266_A2.0361.00
85_D191_D2.0301.00
329_R342_T2.0201.00
137_F233_F1.9881.00
89_V184_L1.9811.00
107_E110_R1.9421.00
311_L366_G1.8841.00
227_V261_E1.8791.00
282_L368_L1.8541.00
159_L175_N1.8451.00
316_Y360_I1.8411.00
230_N344_E1.8291.00
301_S318_G1.8011.00
271_I336_Y1.7921.00
85_D194_L1.7841.00
124_G175_N1.7591.00
87_S191_D1.7331.00
119_E182_V1.7281.00
130_K180_S1.7061.00
234_P268_Y1.6651.00
111_S262_P1.6631.00
108_I266_A1.6521.00
106_R119_E1.6391.00
64_R68_P1.6371.00
152_F181_L1.6351.00
120_L152_F1.6331.00
279_L328_F1.6100.99
272_T336_Y1.6050.99
259_L264_S1.6050.99
253_F256_I1.5980.99
169_S373_F1.5850.99
301_S305_I1.5750.99
227_V260_T1.5730.99
200_M204_R1.5710.99
122_A174_F1.5670.99
290_Y321_D1.5570.99
96_I103_V1.5550.99
289_I343_V1.5380.99
93_I105_C1.5340.99
42_Y62_I1.5310.99
121_K178_S1.5200.99
171_I175_N1.5120.99
121_K180_S1.5110.99
159_L171_I1.5040.99
132_H182_V1.5030.99
322_I344_E1.4870.99
90_E118_W1.4860.99
123_G178_S1.4860.99
100_F157_M1.4730.99
191_D195_N1.4510.99
38_K43_C1.4330.99
103_V120_L1.4320.99
174_F179_L1.4220.99
122_A181_L1.4040.98
145_T190_V1.4010.98
244_K254_P1.3900.98
192_L204_R1.3730.98
316_Y319_V1.3680.98
97_I103_V1.3580.98
30_K59_I1.3390.98
40_Q43_C1.3330.98
343_V367_I1.3170.98
324_S327_G1.2970.97
42_Y45_G1.2960.97
143_I357_F1.2890.97
93_I120_L1.2890.97
48_I53_G1.2790.97
314_N364_T1.2670.97
59_I65_F1.2670.97
271_I332_F1.2630.97
91_K95_K1.2520.97
159_L174_F1.2450.97
293_Y334_H1.2430.97
272_T331_W1.2420.97
143_I284_T1.2390.97
108_I119_E1.2360.97
112_V203_R1.2350.97
190_V194_L1.2340.97
142_W193_V1.2330.97
230_N283_H1.2300.97
85_D88_A1.1880.96
38_K46_Y1.1790.96
205_D261_E1.1760.95
282_L364_T1.1760.95
125_E128_V1.1700.95
207_L222_A1.1670.95
269_R272_T1.1660.95
201_G283_H1.1560.95
332_F340_G1.1550.95
352_L360_I1.1540.95
138_H141_E1.1520.95
113_L204_R1.1510.95
366_G369_W1.1430.95
27_E41_L1.1400.95
105_C120_L1.1390.95
233_F264_S1.1380.95
155_Y179_L1.1250.94
135_A282_L1.1230.94
105_C118_W1.1180.94
271_I331_W1.1170.94
129_K277_D1.1170.94
232_Q260_T1.1140.94
201_G344_E1.1050.94
124_G128_V1.1030.94
286_G321_D1.1000.94
131_V372_L1.1000.94
144_T148_L1.0990.94
349_Q352_L1.0960.93
302_A306_K1.0950.93
155_Y170_P1.0910.93
92_E149_L1.0890.93
130_K178_S1.0780.93
43_C46_Y1.0780.93
308_F364_T1.0720.93
31_S40_Q1.0720.93
150_K361_Y1.0650.92
290_Y294_K1.0590.92
324_S329_R1.0450.92
136_S190_V1.0380.91
107_E118_W1.0330.91
111_S203_R1.0310.91
268_Y272_T1.0290.91
108_I182_V1.0270.91
38_K42_Y1.0250.91
144_T345_L1.0150.90
230_N322_I1.0140.90
79_E84_Y1.0060.90
139_A283_H0.9940.90
29_L32_A0.9930.90
133_M181_L0.9890.89
327_G331_W0.9890.89
192_L196_G0.9870.89
154_E158_S0.9820.89
103_V122_A0.9810.89
147_V361_Y0.9790.89
279_L332_F0.9790.89
291_W333_I0.9740.89
37_Q40_Q0.9700.88
278_R371_A0.9690.88
48_I55_E0.9670.88
28_L42_Y0.9660.88
110_R114_G0.9650.88
235_S293_Y0.9630.88
37_Q43_C0.9610.88
80_Q153_K0.9600.88
87_S90_E0.9560.88
62_I65_F0.9550.88
28_L31_S0.9540.88
305_I308_F0.9540.88
102_F174_F0.9520.87
81_E358_S0.9500.87
229_L264_S0.9460.87
268_Y331_W0.9440.87
239_I244_K0.9390.87
119_E180_S0.9360.87
44_P47_V0.9250.86
201_G228_D0.9230.86
111_S187_P0.9120.85
185_V267_M0.9110.85
265_I269_R0.9020.84
128_V178_S0.9010.84
161_C171_I0.9010.84
223_N247_A0.9000.84
132_H271_I0.8980.84
100_F156_C0.8930.84
66_L69_R0.8900.84
37_Q44_P0.8880.84
348_G353_P0.8870.83
346_G349_Q0.8870.83
32_A35_S0.8870.83
104_S121_K0.8840.83
334_H337_F0.8840.83
304_V371_A0.8810.83
141_E283_H0.8780.83
346_G352_L0.8760.83
308_F312_S0.8750.83
358_S362_N0.8720.82
93_I152_F0.8710.82
97_I105_C0.8690.82
314_N319_V0.8630.82
192_L200_M0.8620.82
352_L356_Q0.8620.82
207_L227_V0.8590.81
358_S361_Y0.8550.81
312_S366_G0.8550.81
309_E315_I0.8510.81
49_E55_E0.8460.80
308_F314_N0.8390.80
173_L179_L0.8370.80
256_I260_T0.8350.80
361_Y365_S0.8340.79
259_L265_I0.8270.79
83_I353_P0.8250.79
235_S327_G0.8230.79
345_L360_I0.8230.79
301_S313_G0.8230.79
111_S185_V0.8210.78
94_K97_I0.8210.78
182_V267_M0.8210.78
296_L299_E0.8170.78
231_K344_E0.8100.77
37_Q42_Y0.8100.77
353_P357_F0.8090.77
292_G333_I0.8090.77
191_D194_L0.8080.77
128_V173_L0.8070.77
304_V308_F0.8060.77
184_L190_V0.8060.77
244_K325_Y0.8020.77
133_M148_L0.8010.77
287_E352_L0.8000.77
30_K42_Y0.7960.76
106_R270_L0.7940.76
102_F159_L0.7910.76
307_E370_R0.7880.76
31_S38_K0.7870.75
86_D191_D0.7830.75
133_M282_L0.7830.75
39_H42_Y0.7810.75
308_F367_I0.7790.75
108_I116_P0.7780.75
37_Q41_L0.7780.75
96_I152_F0.7770.74
259_L272_T0.7760.74
83_I146_S0.7760.74
132_H267_M0.7730.74
170_P174_F0.7730.74
59_I62_I0.7700.74
49_E56_L0.7690.74
109_G117_I0.7680.74
98_D101_P0.7660.73
104_S123_G0.7660.73
37_Q45_G0.7660.73
231_K322_I0.7590.73
54_K60_Q0.7500.72
34_R37_Q0.7420.71
33_N36_A0.7420.71
294_K324_S0.7410.71
29_L35_S0.7370.71
89_V149_L0.7350.70
92_E153_K0.7330.70
247_A250_Y0.7330.70
36_A43_C0.7300.70
234_P335_H0.7290.70
32_A39_H0.7280.70
130_K270_L0.7250.69
293_Y343_V0.7220.69
300_E308_F0.7190.69
133_M151_W0.7190.69
244_K252_D0.7170.68
201_G322_I0.7130.68
160_C175_N0.7120.68
232_Q261_E0.7110.68
112_V205_D0.7100.68
95_K99_V0.7080.67
135_A183_P0.7080.67
153_K157_M0.7060.67
137_F185_V0.7060.67
300_E311_L0.7050.67
203_R262_P0.7030.67
41_L45_G0.7030.67
48_I51_H0.6980.66
40_Q46_Y0.6980.66
108_I117_I0.6970.66
63_K66_L0.6970.66
301_S308_F0.6960.66
139_A193_V0.6960.66
246_T254_P0.6920.66
106_R182_V0.6920.66
305_I309_E0.6920.66
100_F160_C0.6920.66
207_L221_K0.6920.66
269_R273_E0.6900.65
142_W198_E0.6880.65
38_K44_P0.6850.65
265_I268_Y0.6830.65
84_Y88_A0.6820.65
332_F336_Y0.6820.65
348_G351_P0.6780.64
148_L181_L0.6770.64
86_D184_L0.6730.64
345_L352_L0.6730.64
182_V332_F0.6700.63
28_L39_H0.6690.63
161_C167_G0.6650.63
301_S341_Y0.6640.62
178_S193_V0.6610.62
305_I312_S0.6610.62
172_K176_S0.6600.62
65_F69_R0.6600.62
97_I104_S0.6600.62
369_W373_F0.6590.62
364_T368_L0.6580.62
33_N39_H0.6570.62
29_L36_A0.6540.61
136_S144_T0.6520.61
308_F366_G0.6520.61
117_I187_P0.6510.61
197_S251_R0.6510.61
233_F267_M0.6480.61
114_G248_P0.6480.61
233_F266_A0.6470.60
26_E31_S0.6460.60
50_E54_K0.6440.60
102_F124_G0.6440.60
261_E297_E0.6430.60
134_N279_L0.6430.60
87_S91_K0.6420.60
138_H230_N0.6420.60
253_F266_A0.6420.60
285_Q350_N0.6410.60
288_E321_D0.6400.60
238_E245_P0.6390.60
304_V367_I0.6380.59
245_P254_P0.6360.59
35_S38_K0.6350.59
179_L372_L0.6320.59
151_W365_S0.6310.59
84_Y146_S0.6310.59
26_E34_R0.6230.58
138_H283_H0.6230.58
300_E371_A0.6200.57
48_I57_Q0.6180.57
141_E230_N0.6180.57
169_S369_W0.6180.57
284_T342_T0.6140.57
43_C48_I0.6130.56
360_I363_A0.6130.56
280_L286_G0.6110.56
308_F311_L0.6110.56
58_T62_I0.6080.56
193_V198_E0.6060.56
154_E365_S0.6060.56
142_W190_V0.6060.56
83_I352_L0.6060.56
341_Y370_R0.6040.55
29_L42_Y0.6030.55
198_E357_F0.6020.55
174_F180_S0.6010.55
252_D321_D0.6010.55
138_H344_E0.6000.55
31_S36_A0.5990.55
288_E317_K0.5990.55
290_Y342_T0.5980.55
42_Y65_F0.5970.54
252_D322_I0.5960.54
228_D283_H0.5960.54
69_R294_K0.5960.54
43_C47_V0.5960.54
141_E344_E0.5950.54
132_H270_L0.5950.54
186_N189_G0.5950.54
290_Y329_R0.5920.54
137_F281_A0.5880.53
302_A318_G0.5870.53
114_G118_W0.5870.53
37_Q46_Y0.5850.53
301_S314_N0.5840.53
80_Q84_Y0.5840.53
104_S126_H0.5830.53
130_K275_P0.5820.53
27_E33_N0.5820.53
26_E32_A0.5820.53
137_F229_L0.5800.52
301_S316_Y0.5800.52
138_H228_D0.5800.52
233_F268_Y0.5790.52
61_D69_R0.5780.52
206_E225_N0.5770.52
85_D195_N0.5760.52
61_D68_P0.5740.52
123_G128_V0.5730.51
319_V322_I0.5720.51
289_I304_V0.5710.51
322_I326_A0.5710.51
57_Q130_K0.5690.51
287_E349_Q0.5680.51
158_S167_G0.5670.51
29_L33_N0.5650.50
291_W318_G0.5640.50
102_F123_G0.5630.50
204_R225_N0.5630.50
132_H279_L0.5620.50
284_T289_I0.5610.50
271_I328_F0.5610.50
294_K322_I0.5590.50
190_V193_V0.5590.50
42_Y46_Y0.5590.50
228_D344_E0.5580.50
159_L167_G0.5530.49
198_E204_R0.5520.49
245_P325_Y0.5500.49
33_N56_L0.5500.49
261_E264_S0.5490.48
145_T194_L0.5470.48
282_L343_V0.5470.48
238_E325_Y0.5460.48
36_A40_Q0.5460.48
32_A37_Q0.5450.48
51_H60_Q0.5450.48
297_E303_A0.5440.48
151_W368_L0.5430.48
285_Q292_G0.5420.48
231_K294_K0.5410.48
205_D227_V0.5410.48
143_I345_L0.5410.48
83_I292_G0.5410.48
35_S45_G0.5410.48
35_S40_Q0.5390.47
35_S50_E0.5390.47
87_S115_R0.5370.47
140_N350_N0.5340.47
31_S39_H0.5330.47
359_H362_N0.5330.47
134_N146_S0.5320.46
32_A44_P0.5310.46
41_L44_P0.5310.46
190_V357_F0.5310.46
139_A145_T0.5310.46
33_N37_Q0.5310.46
62_I69_R0.5300.46
243_R254_P0.5300.46
200_M203_R0.5280.46
86_D89_V0.5270.46
287_E345_L0.5260.46
111_S115_R0.5250.46
352_L361_Y0.5250.46
300_E305_I0.5240.45
40_Q44_P0.5240.45
202_A228_D0.5240.45
69_R351_P0.5240.45
147_V345_L0.5220.45
226_G237_W0.5210.45
354_F357_F0.5210.45
237_W258_P0.5210.45
88_A321_D0.5210.45
349_Q357_F0.5210.45
131_V179_L0.5200.45
115_R204_R0.5190.45
93_I183_P0.5180.45
146_S357_F0.5180.45
93_I118_W0.5170.45
39_H72_K0.5170.45
38_K45_G0.5170.45
28_L41_L0.5160.44
140_N255_G0.5150.44
103_V152_F0.5140.44
254_P325_Y0.5130.44
90_E94_K0.5100.44
73_L77_W0.5100.44
32_A40_Q0.5100.44
128_V144_T0.5090.44
234_P300_E0.5070.43
169_S173_L0.5040.43
40_Q45_G0.5040.43
155_Y181_L0.5040.43
283_H290_Y0.5040.43
34_R54_K0.5030.43
307_E310_E0.5010.43
27_E42_Y0.5010.43
124_G174_F0.5000.42
316_Y364_T0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2boaA 1 0.9495 100 0.238 Contact Map
1ayeA 1 0.9495 100 0.239 Contact Map
4p10A 1 0.9495 100 0.241 Contact Map
1pcaA 1 0.9495 100 0.242 Contact Map
1kwmA 1 0.9495 100 0.247 Contact Map
1jqgA 1 0.9388 100 0.262 Contact Map
2bo9A 2 0.7553 100 0.363 Contact Map
1dtdA 1 0.7473 100 0.363 Contact Map
1z5rA 1 0.7473 100 0.367 Contact Map
1m4lA 1 0.7606 100 0.368 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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