YQGS - BACSU - GREMLIN Contacts

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YQGS - Lipoteichoic acid synthase-like YqgS

UniProt:	P54496	Sequences: MRKTFFSKISFMLIAILLMWLKTYAVYKTSFHIKIDNLTQEFILFINPLSFLLLIFGLSLFLKGKNRNRYIIAMSCLVTFVLLANMVFYRFYNDFLTIPVLFQTSNMGDLGSSIGTLLEPTDLLLAVDIAVLIWLHIRQKAFQSDIPSTKNERAAYFLFVASVYFFNLGLSEAERPQLLTRSFDREMLVKNISLFNFHIYDGVLQSKQSAQRALADSNSLTEIENYVTANAKDANKRLFGAAKGRNVILVSLESTQSFVINEKLNGEEITPFLNDFIKQSYNFNNVYHQTGQGKTSDSEFIVDNSLYPLGRGAVFFTNAGNQYMAAPEILKNSGYYSAVLHANNKSFWNRDLMYDSFGYDSFFDINSYDVTDENSVGWGLKDKEFFEQSSELMKNLPQPFYSRLITLTNHFPFDLDEEDQLIDEYDSNSQTLNKYFPTVRYQDEALKRFIEKLKEDGLYDNSVIVLYGDHYGISENHNEAMGQFLGKEITPFEEVQLQKVPLVIHIPGITDKKPQTIETVGGQIDIRPTLMNLLGIDTKDQIQFGNDLLSDEKLDFTVLRDGSFITDQVVYTDGACYDKETGKPLEETKQCEAFADKAKQELSLSDEIIYGDLLRFYDQKRLDNSSKRKEKQMLDQAS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	638 (535)
Sequences:	3946 (3276)
Seq/√Len:	141.6

ECOLI - YEJM EPTC EPTB YHBX EPTA OPGE YIDJ YDEN ASLA
BACSU - YQGS LTAS2 LTAS1 YVGJ
HALSA - Q9HSV3 Q9HQ44

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
284_N	518_E	6.573	1.00
272_F	447_K	6.272	1.00
331_K	360_D	5.694	1.00
532_N	547_D	4.638	1.00
394_K	456_D	4.421	1.00
272_F	275_D	4.071	1.00
250_V	466_L	4.020	1.00
521_G	548_L	3.921	1.00
248_I	464_I	3.632	1.00
506_I	509_I	3.529	1.00
489_I	492_F	3.315	1.00
245_R	461_N	3.265	1.00
286_V	521_G	3.233	1.00
247_V	534_L	3.204	1.00
252_L	255_T	3.201	1.00
20_W	23_T	3.167	1.00
390_S	452_K	3.138	1.00
279_Q	454_K	3.094	1.00
336_Y	398_Q	3.046	1.00
454_K	459_Y	3.036	1.00
261_N	270_T	2.913	1.00
451_E	455_E	2.839	1.00
247_V	330_L	2.739	1.00
22_K	25_A	2.697	1.00
330_L	534_L	2.627	1.00
447_K	451_E	2.575	1.00
248_I	462_S	2.539	1.00
451_E	454_K	2.520	1.00
507_P	510_T	2.485	1.00
246_N	400_F	2.411	1.00
448_R	451_E	2.381	1.00
506_I	510_T	2.358	1.00
246_N	462_S	2.343	1.00
489_I	493_E	2.324	1.00
268_E	274_N	2.287	1.00
459_Y	505_H	2.275	1.00
556_F	559_L	2.248	1.00
463_V	504_I	2.226	1.00
249_L	401_Y	2.129	1.00
23_T	27_Y	2.121	1.00
23_T	26_V	2.039	1.00
270_T	274_N	2.006	1.00
450_I	464_I	1.998	1.00
392_L	395_N	1.978	1.00
453_L	464_I	1.977	1.00
364_D	367_S	1.971	1.00
529_T	549_L	1.936	1.00
502_L	526_I	1.922	1.00
428_N	433_N	1.870	1.00
41_E	45_F	1.857	1.00
286_V	502_L	1.852	1.00
485_L	488_E	1.832	1.00
85_N	95_F	1.824	1.00
386_F	406_T	1.819	1.00
410_H	469_D	1.813	1.00
417_E	420_Q	1.812	1.00
409_N	439_V	1.811	1.00
390_S	456_D	1.805	1.00
312_G	315_F	1.797	1.00
22_K	27_Y	1.792	1.00
388_Q	391_E	1.792	1.00
263_K	282_N	1.790	1.00
465_V	504_I	1.782	1.00
452_K	455_E	1.770	1.00
37_N	41_E	1.769	1.00
251_S	299_E	1.768	1.00
216_D	219_S	1.762	1.00
400_F	458_L	1.736	1.00
459_Y	464_I	1.735	1.00
305_S	528_P	1.719	1.00
383_K	448_R	1.716	1.00
338_A	402_S	1.709	1.00
261_N	274_N	1.705	1.00
555_D	559_L	1.695	1.00
424_E	429_S	1.691	1.00
275_D	447_K	1.689	1.00
219_S	222_E	1.689	1.00
16_I	20_W	1.689	1.00
250_V	446_L	1.687	1.00
490_T	493_E	1.687	1.00
284_N	516_T	1.682	1.00
554_L	557_T	1.676	1.00
468_G	500_V	1.671	1.00
249_L	465_V	1.668	1.00
340_L	392_L	1.667	1.00
162_S	165_F	1.654	1.00
424_E	427_S	1.641	1.00
252_L	442_Q	1.618	1.00
416_D	419_D	1.611	1.00
199_I	202_G	1.610	1.00
224_E	228_T	1.607	1.00
215_A	219_S	1.601	1.00
272_F	450_I	1.594	1.00
281_Y	549_L	1.593	1.00
444_E	448_R	1.569	1.00
416_D	441_Y	1.564	1.00
383_K	441_Y	1.558	1.00
467_Y	523_Q	1.556	1.00
257_S	499_K	1.548	1.00
329_I	531_M	1.548	1.00
255_T	259_V	1.544	1.00
259_V	439_V	1.542	1.00
344_N	347_F	1.532	1.00
273_L	446_L	1.527	1.00
134_W	137_I	1.526	1.00
255_T	442_Q	1.523	1.00
22_K	26_V	1.519	1.00
134_W	138_R	1.517	1.00
449_F	464_I	1.515	1.00
304_N	325_A	1.510	1.00
212_R	215_A	1.508	1.00
247_V	465_V	1.507	1.00
126_A	129_I	1.507	1.00
19_M	22_K	1.505	1.00
313_A	316_F	1.505	1.00
389_S	404_L	1.500	1.00
460_D	508_G	1.499	1.00
452_K	456_D	1.498	1.00
312_G	316_F	1.496	1.00
389_S	393_M	1.460	1.00
45_F	48_P	1.446	1.00
252_L	446_L	1.444	1.00
20_W	27_Y	1.438	1.00
280_S	505_H	1.438	1.00
424_E	428_N	1.434	1.00
295_T	405_I	1.415	1.00
467_Y	526_I	1.414	1.00
276_F	446_L	1.411	1.00
243_K	461_N	1.401	1.00
14_I	22_K	1.398	1.00
386_F	390_S	1.390	1.00
270_T	273_L	1.386	1.00
302_V	467_Y	1.383	1.00
385_F	404_L	1.366	1.00
390_S	394_K	1.358	1.00
109_D	113_S	1.352	1.00
252_L	466_L	1.350	1.00
351_D	355_D	1.347	1.00
245_R	463_V	1.338	1.00
261_N	268_E	1.335	1.00
463_V	530_L	1.321	1.00
133_I	137_I	1.313	1.00
44_L	48_P	1.312	1.00
386_F	449_F	1.308	1.00
26_V	29_T	1.305	1.00
163_V	167_N	1.302	1.00
302_V	526_I	1.300	1.00
123_L	127_V	1.294	1.00
392_L	396_L	1.294	1.00
531_M	536_I	1.292	1.00
345_K	364_D	1.291	1.00
394_K	452_K	1.290	1.00
167_N	171_S	1.289	1.00
440_R	444_E	1.286	1.00
339_V	405_I	1.286	1.00
311_R	314_V	1.284	1.00
280_S	503_V	1.282	1.00
45_F	49_L	1.277	1.00
450_I	454_K	1.272	1.00
250_V	386_F	1.261	1.00
272_F	451_E	1.258	1.00
445_A	448_R	1.254	1.00
465_V	530_L	1.252	1.00
339_V	354_Y	1.249	1.00
251_S	302_V	1.249	1.00
246_N	460_D	1.248	1.00
181_R	184_D	1.248	1.00
289_Q	522_G	1.235	1.00
387_E	448_R	1.235	1.00
16_I	22_K	1.233	1.00
287_Y	499_K	1.232	1.00
253_E	469_D	1.228	1.00
391_E	395_N	1.225	1.00
450_I	466_L	1.225	1.00
336_Y	361_S	1.223	1.00
15_A	22_K	1.222	1.00
283_F	502_L	1.220	1.00
448_R	452_K	1.210	1.00
285_N	499_K	1.209	1.00
275_D	279_Q	1.207	1.00
197_F	201_D	1.206	1.00
335_Y	399_P	1.200	1.00
281_Y	515_Q	1.197	1.00
271_P	443_D	1.195	1.00
203_V	207_K	1.194	1.00
256_Q	471_Y	1.192	1.00
159_F	162_S	1.189	1.00
346_S	351_D	1.176	1.00
110_L	113_S	1.176	1.00
277_I	282_N	1.171	1.00
90_R	122_D	1.166	1.00
281_Y	517_I	1.163	1.00
238_L	549_L	1.159	0.99
267_E	436_F	1.159	0.99
17_L	22_K	1.158	0.99
132_L	135_L	1.158	0.99
159_F	163_V	1.157	0.99
528_P	545_G	1.151	0.99
53_L	57_G	1.147	0.99
224_E	227_V	1.146	0.99
276_F	450_I	1.143	0.99
18_L	22_K	1.134	0.99
17_L	20_W	1.132	0.99
248_I	400_F	1.127	0.99
220_L	223_I	1.126	0.99
333_S	536_I	1.125	0.99
182_S	185_R	1.124	0.99
57_G	60_L	1.123	0.99
255_T	439_V	1.122	0.99
547_D	550_S	1.120	0.99
338_A	400_F	1.119	0.99
76_C	80_F	1.117	0.99
191_N	194_L	1.114	0.99
310_G	314_V	1.109	0.99
22_K	31_F	1.105	0.99
425_Y	428_N	1.103	0.99
198_H	203_V	1.100	0.99
109_D	114_I	1.099	0.99
183_F	186_E	1.099	0.99
201_D	204_L	1.099	0.99
382_D	386_F	1.096	0.99
393_M	402_S	1.092	0.99
249_L	526_I	1.090	0.99
488_E	491_P	1.089	0.99
295_T	298_S	1.089	0.99
20_W	26_V	1.085	0.99
124_L	127_V	1.084	0.99
199_I	206_S	1.083	0.99
219_S	223_I	1.079	0.99
189_V	192_I	1.078	0.99
327_P	359_Y	1.076	0.99
345_K	351_D	1.073	0.99
147_P	150_K	1.072	0.99
326_A	530_L	1.070	0.99
130_A	134_W	1.066	0.99
409_N	438_T	1.066	0.99
193_S	196_N	1.066	0.99
255_T	270_T	1.065	0.99
247_V	401_Y	1.063	0.99
349_N	352_L	1.053	0.99
488_E	492_F	1.045	0.99
349_N	354_Y	1.044	0.99
285_N	520_V	1.042	0.99
422_I	440_R	1.037	0.99
22_K	29_T	1.035	0.99
248_I	393_M	1.032	0.99
310_G	313_A	1.029	0.99
177_Q	181_R	1.028	0.99
259_V	436_F	1.027	0.99
289_Q	301_I	1.026	0.99
444_E	447_K	1.025	0.99
190_K	195_F	1.023	0.99
251_S	467_Y	1.020	0.99
253_E	410_H	1.020	0.99
463_V	506_I	1.013	0.99
415_L	437_P	1.012	0.99
23_T	33_I	1.012	0.99
197_F	202_G	1.011	0.99
340_L	402_S	1.011	0.99
127_V	131_V	1.011	0.99
446_L	466_L	1.010	0.99
19_M	23_T	1.009	0.99
343_N	347_F	1.008	0.99
486_G	489_I	1.007	0.99
164_Y	168_L	1.006	0.99
10_S	15_A	1.003	0.99
251_S	403_R	1.001	0.98
222_E	225_N	1.000	0.98
415_L	420_Q	0.998	0.98
484_F	488_E	0.996	0.98
211_Q	216_D	0.996	0.98
215_A	220_L	0.994	0.98
272_F	444_E	0.991	0.98
247_V	463_V	0.983	0.98
223_I	227_V	0.981	0.98
293_G	297_D	0.978	0.98
334_G	399_P	0.978	0.98
27_Y	30_S	0.977	0.98
257_S	282_N	0.976	0.98
123_L	126_A	0.976	0.98
198_H	201_D	0.974	0.98
421_L	440_R	0.973	0.98
69_R	73_A	0.970	0.98
329_I	332_N	0.967	0.98
453_L	457_G	0.966	0.98
16_I	27_Y	0.951	0.98
131_V	135_L	0.948	0.98
199_I	203_V	0.945	0.98
138_R	141_A	0.943	0.98
336_Y	396_L	0.942	0.98
330_L	531_M	0.941	0.98
15_A	19_M	0.934	0.98
255_T	466_L	0.934	0.98
149_T	152_E	0.933	0.98
219_S	224_E	0.932	0.98
20_W	29_T	0.932	0.98
148_S	152_E	0.931	0.98
359_Y	403_R	0.930	0.98
419_D	422_I	0.928	0.98
383_K	444_E	0.928	0.98
13_L	16_I	0.928	0.98
70_Y	74_M	0.924	0.97
162_S	166_F	0.924	0.97
414_D	434_K	0.923	0.97
433_N	437_P	0.917	0.97
419_D	423_D	0.917	0.97
453_L	458_L	0.917	0.97
554_L	559_L	0.912	0.97
16_I	23_T	0.912	0.97
268_E	440_R	0.909	0.97
275_D	278_K	0.904	0.97
282_N	516_T	0.903	0.97
29_T	32_H	0.902	0.97
384_E	388_Q	0.902	0.97
277_I	503_V	0.901	0.97
149_T	153_R	0.899	0.97
409_N	442_Q	0.898	0.97
168_L	171_S	0.895	0.97
500_V	523_Q	0.894	0.97
255_T	273_L	0.894	0.97
273_L	282_N	0.894	0.97
192_I	195_F	0.893	0.97
135_L	138_R	0.892	0.97
28_K	34_K	0.891	0.97
554_L	558_V	0.886	0.97
23_T	29_T	0.886	0.97
326_A	531_M	0.884	0.97
276_F	503_V	0.884	0.97
350_R	354_Y	0.882	0.97
252_L	386_F	0.880	0.97
121_T	129_I	0.880	0.97
338_A	361_S	0.879	0.97
23_T	28_K	0.879	0.97
169_G	173_A	0.878	0.97
389_S	402_S	0.877	0.97
379_G	407_L	0.872	0.96
223_I	226_Y	0.871	0.96
295_T	410_H	0.869	0.96
466_L	503_V	0.869	0.96
415_L	422_I	0.869	0.96
191_N	196_N	0.868	0.96
30_S	33_I	0.867	0.96
14_I	18_L	0.865	0.96
131_V	137_I	0.860	0.96
214_L	219_S	0.859	0.96
502_L	548_L	0.857	0.96
388_Q	392_L	0.851	0.96
215_A	218_N	0.850	0.96
527_R	531_M	0.850	0.96
181_R	195_F	0.850	0.96
386_F	442_Q	0.849	0.96
384_E	387_E	0.847	0.96
273_L	503_V	0.846	0.96
153_R	156_Y	0.845	0.96
111_G	115_G	0.844	0.96
275_D	454_K	0.844	0.96
20_W	33_I	0.844	0.96
249_L	302_V	0.842	0.96
211_Q	215_A	0.841	0.96
200_Y	204_L	0.838	0.95
212_R	217_S	0.836	0.95
415_L	419_D	0.834	0.95
184_D	195_F	0.833	0.95
309_L	312_G	0.832	0.95
221_T	224_E	0.832	0.95
442_Q	445_A	0.832	0.95
311_R	315_F	0.832	0.95
294_K	297_D	0.830	0.95
198_H	202_G	0.829	0.95
255_T	260_I	0.827	0.95
85_N	96_L	0.826	0.95
166_F	172_E	0.826	0.95
276_F	466_L	0.825	0.95
44_L	47_N	0.824	0.95
396_L	400_F	0.824	0.95
195_F	201_D	0.823	0.95
391_E	452_K	0.823	0.95
17_L	23_T	0.821	0.95
410_H	470_H	0.820	0.95
161_A	165_F	0.820	0.95
545_G	548_L	0.819	0.95
341_H	350_R	0.818	0.95
408_T	438_T	0.818	0.95
84_A	96_L	0.816	0.95
11_F	15_A	0.816	0.95
168_L	172_E	0.816	0.95
487_K	492_F	0.815	0.95
28_K	32_H	0.814	0.95
308_P	311_R	0.813	0.95
246_N	399_P	0.812	0.95
129_I	136_H	0.811	0.95
324_M	332_N	0.810	0.95
177_Q	184_D	0.808	0.95
336_Y	360_D	0.807	0.94
484_F	487_K	0.806	0.94
22_K	30_S	0.806	0.94
398_Q	461_N	0.805	0.94
172_E	176_P	0.804	0.94
221_T	225_N	0.803	0.94
292_Q	298_S	0.801	0.94
127_V	130_A	0.800	0.94
20_W	24_Y	0.799	0.94
338_A	392_L	0.797	0.94
180_T	184_D	0.797	0.94
20_W	31_F	0.793	0.94
485_L	489_I	0.793	0.94
21_L	25_A	0.790	0.94
331_K	337_S	0.788	0.94
244_G	333_S	0.788	0.94
181_R	185_R	0.785	0.94
13_L	17_L	0.783	0.94
56_F	60_L	0.783	0.94
159_F	168_L	0.779	0.93
276_F	280_S	0.778	0.93
215_A	222_E	0.778	0.93
222_E	226_Y	0.776	0.93
211_Q	214_L	0.775	0.93
15_A	27_Y	0.775	0.93
157_F	161_A	0.774	0.93
126_A	130_A	0.774	0.93
108_G	112_S	0.772	0.93
337_S	401_Y	0.772	0.93
445_A	449_F	0.771	0.93
406_T	449_F	0.770	0.93
46_I	167_N	0.770	0.93
248_I	453_L	0.766	0.93
37_N	40_Q	0.763	0.93
338_A	396_L	0.761	0.93
532_N	550_S	0.760	0.93
460_D	507_P	0.760	0.93
359_Y	362_F	0.760	0.93
37_N	43_I	0.758	0.92
190_K	196_N	0.757	0.92
363_F	392_L	0.756	0.92
32_H	35_I	0.756	0.92
121_T	125_L	0.755	0.92
169_G	172_E	0.752	0.92
46_I	50_S	0.752	0.92
179_L	182_S	0.752	0.92
54_L	58_L	0.751	0.92
383_K	419_D	0.751	0.92
27_Y	31_F	0.750	0.92
387_E	390_S	0.748	0.92
24_Y	28_K	0.748	0.92
66_N	69_R	0.748	0.92
304_N	353_M	0.747	0.92
26_V	34_K	0.744	0.92
128_D	131_V	0.743	0.92
155_A	159_F	0.742	0.92
15_A	25_A	0.741	0.92
148_S	158_L	0.739	0.91
217_S	220_L	0.739	0.91
236_K	239_F	0.739	0.91
24_Y	29_T	0.738	0.91
25_A	33_I	0.737	0.91
487_K	493_E	0.736	0.91
210_A	214_L	0.734	0.91
160_V	164_Y	0.734	0.91
129_I	137_I	0.733	0.91
145_D	148_S	0.733	0.91
11_F	27_Y	0.731	0.91
226_Y	229_A	0.731	0.91
232_K	236_K	0.731	0.91
177_Q	185_R	0.731	0.91
555_D	558_V	0.731	0.91
256_Q	474_S	0.731	0.91
88_F	297_D	0.726	0.91
457_G	460_D	0.724	0.91
106_N	109_D	0.721	0.90
381_K	384_E	0.719	0.90
301_I	523_Q	0.717	0.90
525_D	545_G	0.717	0.90
135_L	158_L	0.714	0.90
233_D	236_K	0.714	0.90
15_A	23_T	0.713	0.90
293_G	298_S	0.712	0.90
45_F	50_S	0.712	0.90
135_L	139_Q	0.711	0.90
358_G	364_D	0.711	0.90
184_D	190_K	0.710	0.90
435_Y	439_V	0.710	0.90
131_V	136_H	0.709	0.90
15_A	18_L	0.706	0.90
14_I	24_Y	0.706	0.90
200_Y	203_V	0.705	0.89
476_N	487_K	0.705	0.89
249_L	326_A	0.704	0.89
146_I	149_T	0.704	0.89
177_Q	182_S	0.701	0.89
256_Q	435_Y	0.700	0.89
309_L	313_A	0.699	0.89
293_G	296_S	0.698	0.89
212_R	218_N	0.696	0.89
335_Y	534_L	0.694	0.89
326_A	527_R	0.694	0.89
180_T	183_F	0.693	0.89
11_F	17_L	0.692	0.89
26_V	31_F	0.692	0.89
220_L	224_E	0.691	0.88
425_Y	429_S	0.689	0.88
216_D	220_L	0.687	0.88
263_K	266_G	0.686	0.88
85_N	198_H	0.686	0.88
150_K	165_F	0.685	0.88
361_S	364_D	0.685	0.88
165_F	169_G	0.684	0.88
471_Y	474_S	0.684	0.88
28_K	31_F	0.683	0.88
24_Y	31_F	0.683	0.88
253_E	406_T	0.682	0.88
519_T	548_L	0.681	0.88
299_E	350_R	0.680	0.88
247_V	530_L	0.679	0.88
473_I	497_L	0.676	0.87
47_N	56_F	0.675	0.87
96_L	260_I	0.675	0.87
215_A	223_I	0.672	0.87
295_T	299_E	0.672	0.87
217_S	224_E	0.671	0.87
43_I	46_I	0.671	0.87
251_S	405_I	0.671	0.87
270_T	443_D	0.670	0.87
546_N	554_L	0.669	0.87
527_R	543_Q	0.668	0.87
25_A	28_K	0.668	0.87
415_L	423_D	0.667	0.87
209_S	214_L	0.667	0.87
422_I	437_P	0.666	0.87
316_F	320_G	0.666	0.87
235_N	238_L	0.665	0.87
349_N	353_M	0.664	0.86
419_D	444_E	0.662	0.86
268_E	271_P	0.660	0.86
308_P	312_G	0.659	0.86
177_Q	195_F	0.659	0.86
31_F	34_K	0.658	0.86
168_L	176_P	0.655	0.86
260_I	270_T	0.655	0.86
17_L	25_A	0.653	0.86
450_I	459_Y	0.652	0.85
292_Q	295_T	0.649	0.85
158_L	162_S	0.648	0.85
336_Y	530_L	0.646	0.85
29_T	34_K	0.645	0.85
257_S	263_K	0.645	0.85
74_M	148_S	0.644	0.85
383_K	387_E	0.644	0.85
442_Q	523_Q	0.643	0.85
292_Q	296_S	0.643	0.85
488_E	493_E	0.643	0.85
296_S	299_E	0.642	0.85
47_N	60_L	0.642	0.85
136_H	140_K	0.642	0.85
129_I	132_L	0.639	0.84
65_K	68_N	0.639	0.84
277_I	284_N	0.637	0.84
502_L	521_G	0.636	0.84
194_L	198_H	0.635	0.84
514_P	517_I	0.635	0.84
424_E	430_Q	0.635	0.84
14_I	19_M	0.635	0.84
196_N	199_I	0.634	0.84
376_V	407_L	0.633	0.84
282_N	503_V	0.633	0.84
100_V	103_Q	0.633	0.84
210_A	217_S	0.633	0.84
197_F	204_L	0.632	0.84
327_P	358_G	0.632	0.84
330_L	401_Y	0.630	0.83
173_A	176_P	0.629	0.83
551_D	555_D	0.629	0.83
217_S	225_N	0.629	0.83
10_S	14_I	0.627	0.83
309_L	314_V	0.627	0.83
27_Y	32_H	0.626	0.83
208_Q	211_Q	0.626	0.83
150_K	153_R	0.626	0.83
265_N	436_F	0.626	0.83
504_I	529_T	0.625	0.83
178_L	181_R	0.625	0.83
404_L	449_F	0.623	0.83
225_N	228_T	0.623	0.83
156_Y	160_V	0.623	0.83
420_Q	423_D	0.623	0.83
275_D	451_E	0.622	0.83
28_K	33_I	0.621	0.83
22_K	33_I	0.621	0.83
248_I	449_F	0.621	0.83
435_Y	472_G	0.619	0.82
382_D	385_F	0.619	0.82
22_K	28_K	0.619	0.82
245_R	335_Y	0.618	0.82
21_L	26_V	0.618	0.82
166_F	169_G	0.617	0.82
159_F	167_N	0.616	0.82
121_T	131_V	0.616	0.82
337_S	360_D	0.615	0.82
486_G	492_F	0.614	0.82
292_Q	297_D	0.614	0.82
196_N	203_V	0.614	0.82
92_Y	97_T	0.613	0.82
486_G	491_P	0.611	0.82
115_G	118_L	0.611	0.82
122_D	125_L	0.610	0.81
218_N	221_T	0.610	0.81
300_F	314_V	0.610	0.81
143_Q	148_S	0.609	0.81
274_N	277_I	0.609	0.81
247_V	326_A	0.605	0.81
373_E	376_V	0.605	0.81
295_T	469_D	0.605	0.81
41_E	44_L	0.602	0.81
109_D	112_S	0.601	0.81
269_I	436_F	0.600	0.80
242_A	463_V	0.598	0.80
171_S	174_E	0.597	0.80
350_R	353_M	0.597	0.80
288_H	292_Q	0.596	0.80
413_F	431_T	0.595	0.80
277_I	280_S	0.595	0.80
46_I	49_L	0.595	0.80
391_E	394_K	0.594	0.80
15_A	21_L	0.594	0.80
253_E	409_N	0.594	0.80
271_P	274_N	0.594	0.80
215_A	224_E	0.593	0.80
401_Y	530_L	0.593	0.80
44_L	54_L	0.593	0.80
157_F	170_L	0.592	0.80
244_G	399_P	0.592	0.80
187_M	190_K	0.590	0.79
49_L	57_G	0.589	0.79
26_V	30_S	0.587	0.79
246_N	463_V	0.586	0.79
46_I	52_L	0.584	0.79
255_T	409_N	0.584	0.79
286_V	526_I	0.584	0.79
217_S	226_Y	0.584	0.79
466_L	505_H	0.579	0.78
193_S	200_Y	0.578	0.78
352_L	356_S	0.578	0.78
12_M	18_L	0.577	0.78
121_T	130_A	0.576	0.78
264_L	436_F	0.575	0.78
354_Y	362_F	0.574	0.77
447_K	450_I	0.572	0.77
120_P	131_V	0.569	0.77
342_A	407_L	0.568	0.77
18_L	25_A	0.568	0.77
192_I	196_N	0.567	0.77
212_R	216_D	0.566	0.76
262_E	269_I	0.566	0.76
211_Q	217_S	0.566	0.76
412_P	523_Q	0.565	0.76
120_P	124_L	0.564	0.76
19_M	33_I	0.564	0.76
379_G	412_P	0.563	0.76
45_F	51_F	0.563	0.76
91_F	413_F	0.562	0.76
23_T	34_K	0.561	0.76
154_A	166_F	0.560	0.76
217_S	221_T	0.560	0.76
393_M	453_L	0.560	0.76
81_V	84_A	0.560	0.76
313_A	317_T	0.559	0.76
327_P	401_Y	0.559	0.76
18_L	29_T	0.557	0.75
419_D	441_Y	0.556	0.75
23_T	30_S	0.556	0.75
363_F	367_S	0.555	0.75
229_A	232_K	0.555	0.75
101_L	277_I	0.554	0.75
347_F	350_R	0.554	0.75
202_G	206_S	0.554	0.75
158_L	169_G	0.553	0.75
284_N	517_I	0.553	0.75
342_A	385_F	0.552	0.75
408_T	441_Y	0.552	0.75
145_D	149_T	0.551	0.75
88_F	97_T	0.551	0.75
162_S	170_L	0.551	0.75
204_L	207_K	0.551	0.75
62_L	66_N	0.550	0.74
85_N	409_N	0.550	0.74
393_M	449_F	0.550	0.74
115_G	465_V	0.550	0.74
240_G	243_K	0.550	0.74
531_M	543_Q	0.549	0.74
137_I	140_K	0.548	0.74
288_H	471_Y	0.548	0.74
296_S	308_P	0.547	0.74
133_I	136_H	0.547	0.74
38_L	43_I	0.545	0.74
451_E	518_E	0.545	0.74
14_I	21_L	0.545	0.74
387_E	452_K	0.545	0.74
259_V	432_L	0.544	0.74
436_F	440_R	0.544	0.74
485_L	491_P	0.544	0.74
286_V	289_Q	0.543	0.73
29_T	33_I	0.541	0.73
74_M	326_A	0.541	0.73
442_Q	446_L	0.541	0.73
347_F	354_Y	0.541	0.73
57_G	61_F	0.541	0.73
102_F	106_N	0.541	0.73
45_F	55_I	0.540	0.73
301_I	406_T	0.540	0.73
58_L	62_L	0.540	0.73
245_R	462_S	0.540	0.73
169_G	174_E	0.540	0.73
145_D	152_E	0.539	0.73
71_I	75_S	0.539	0.73
178_L	185_R	0.539	0.73
386_F	445_A	0.539	0.73
71_I	74_M	0.538	0.73
21_L	24_Y	0.538	0.73
239_F	532_N	0.537	0.73
280_S	462_S	0.537	0.73
413_F	472_G	0.534	0.72
127_V	137_I	0.534	0.72
97_T	100_V	0.533	0.72
182_S	196_N	0.533	0.72
301_I	304_N	0.533	0.72
485_L	493_E	0.533	0.72
103_Q	106_N	0.533	0.72
179_L	183_F	0.532	0.72
348_W	354_Y	0.532	0.72
58_L	64_G	0.532	0.72
164_Y	171_S	0.531	0.72
51_F	56_F	0.531	0.72
385_F	445_A	0.531	0.72
246_N	402_S	0.530	0.72
140_K	143_Q	0.530	0.72
426_D	429_S	0.530	0.72
416_D	422_I	0.529	0.72
141_A	145_D	0.529	0.72
10_S	23_T	0.528	0.71
213_A	220_L	0.528	0.71
40_Q	43_I	0.528	0.71
172_E	175_R	0.527	0.71
245_R	399_P	0.527	0.71
553_K	557_T	0.527	0.71
430_Q	434_K	0.526	0.71
155_A	166_F	0.525	0.71
152_E	156_Y	0.525	0.71
419_D	424_E	0.525	0.71
16_I	24_Y	0.524	0.71
253_E	382_D	0.524	0.71
325_A	328_E	0.522	0.71
485_L	492_F	0.522	0.71
177_Q	183_F	0.521	0.70
338_A	363_F	0.521	0.70
328_E	332_N	0.519	0.70
256_Q	472_G	0.518	0.70
164_Y	167_N	0.517	0.70
54_L	57_G	0.517	0.70
201_D	205_Q	0.516	0.70
149_T	160_V	0.515	0.70
254_S	468_G	0.514	0.69
212_R	220_L	0.514	0.69
186_E	190_K	0.514	0.69
380_L	384_E	0.513	0.69
253_E	470_H	0.513	0.69
343_N	407_L	0.513	0.69
129_I	134_W	0.512	0.69
72_I	75_S	0.512	0.69
296_S	348_W	0.511	0.69
191_N	195_F	0.511	0.69
435_Y	471_Y	0.511	0.69
163_V	170_L	0.510	0.69
352_L	355_D	0.510	0.69
189_V	195_F	0.509	0.69
128_D	132_L	0.509	0.69
39_T	77_L	0.508	0.69
13_L	21_L	0.508	0.69
44_L	50_S	0.507	0.68
111_G	114_I	0.507	0.68
446_L	450_I	0.507	0.68
11_F	16_I	0.507	0.68
16_I	21_L	0.507	0.68
164_Y	169_G	0.507	0.68
550_S	553_K	0.506	0.68
353_M	357_F	0.505	0.68
254_S	469_D	0.505	0.68
350_R	362_F	0.505	0.68
342_A	378_W	0.504	0.68
25_A	31_F	0.504	0.68
111_G	526_I	0.504	0.68
116_T	120_P	0.504	0.68
523_Q	526_I	0.503	0.68
411_F	497_L	0.503	0.68
309_L	315_F	0.503	0.68
525_D	528_P	0.503	0.68
341_H	348_W	0.503	0.68
327_P	357_F	0.502	0.68
524_I	528_P	0.502	0.68
188_L	192_I	0.501	0.67
435_Y	438_T	0.501	0.67
461_N	465_V	0.501	0.67
218_N	223_I	0.501	0.67
51_F	58_L	0.500	0.67

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2w8dA	1	0.6505	100	0.429	Contact Map
2w5qA	1	0.6536	100	0.437	Contact Map
4uorA	3	0.6411	100	0.448	Contact Map
4uopA	2	0.6129	100	0.458	Contact Map
3ed4A	3	0.6097	100	0.493	Contact Map
4upiA	2	0.5972	100	0.495	Contact Map
4uplA	2	0.6019	100	0.496	Contact Map
4uphA	2	0.5878	100	0.5	Contact Map
3b5qA	1	0.5925	100	0.503	Contact Map
2vqrA	3	0.5878	100	0.504	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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