GREMLIN Database
YQGM - Uncharacterized glycosyltransferase YqgM
UniProt: P54490 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 359 (331)
Sequences: 58098 (49279)
Seq/√Len: 2708.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
179_F252_C4.6051.00
208_Y235_M3.6541.00
218_L222_E3.3011.00
133_A154_T3.2081.00
255_A271_S3.0521.00
177_F210_V2.8991.00
76_H349_Y2.8591.00
199_I308_A2.7001.00
210_V237_L2.6961.00
195_K224_L2.6851.00
331_Q335_L2.6821.00
175_R208_Y2.6281.00
180_S190_L2.4691.00
201_K233_R2.3811.00
142_K146_D2.2661.00
36_T72_F2.1781.00
195_K304_V2.1521.00
189_G192_Q2.1291.00
176_R315_L2.1251.00
217_S220_C2.1001.00
177_F208_Y2.0391.00
329_R333_F2.0171.00
282_Q287_C2.0171.00
224_L228_Y2.0061.00
212_A248_L2.0061.00
199_I305_Q2.0001.00
317_D320_K1.9691.00
310_L313_S1.9571.00
197_F209_L1.9551.00
177_F251_H1.9431.00
36_T70_K1.9361.00
210_V235_M1.9331.00
33_I346_L1.9001.00
176_R253_E1.8881.00
290_A296_A1.8841.00
295_T331_Q1.8701.00
178_L254_M1.8641.00
313_S320_K1.8461.00
291_V294_K1.8341.00
321_A325_K1.7991.00
275_G329_R1.7781.00
340_L344_S1.7571.00
226_A231_K1.7401.00
76_H100_T1.7341.00
282_Q300_D1.7331.00
139_T142_K1.7321.00
189_G260_S1.7231.00
300_D306_E1.7191.00
154_T351_R1.7191.00
297_I310_L1.7141.00
159_P338_P1.6821.00
133_A348_L1.6721.00
313_S317_D1.6631.00
193_L209_L1.6601.00
142_K155_V1.6541.00
255_A276_V1.6491.00
139_T288_D1.6481.00
99_A131_A1.6151.00
136_V153_I1.6101.00
198_A228_Y1.6031.00
312_D316_K1.5711.00
294_K327_A1.5681.00
181_Y245_I1.5621.00
197_F207_L1.5621.00
320_K323_R1.5421.00
193_L256_V1.5331.00
31_P343_S1.5281.00
291_V331_Q1.5281.00
346_L350_E1.5121.00
303_L306_E1.5041.00
214_E218_L1.5011.00
200_L312_D1.4891.00
241_N244_D1.4781.00
291_V295_T1.4691.00
306_E310_L1.4671.00
297_I313_S1.4621.00
142_K153_I1.4611.00
323_R327_A1.4611.00
139_T155_V1.4411.00
192_Q260_S1.4261.00
28_Y339_R1.4151.00
28_Y342_M1.4151.00
23_N27_S1.4131.00
177_F253_E1.4031.00
212_A237_L1.4001.00
187_E261_Y1.3811.00
240_L244_D1.3801.00
192_Q304_V1.3671.00
210_V248_L1.3611.00
280_V286_F1.3601.00
252_C276_V1.3551.00
244_D247_T1.3411.00
146_D150_H1.3381.00
191_S224_L1.3241.00
135_I345_Y1.2981.00
149_A152_K1.2961.00
135_I348_L1.2951.00
304_V308_A1.2891.00
190_L211_L1.2831.00
196_V307_A1.2821.00
210_V252_C1.2821.00
178_L256_V1.2811.00
299_A310_L1.2781.00
180_S193_L1.2731.00
246_R274_Q1.2661.00
172_S175_R1.2651.00
184_F211_L1.2631.00
199_I304_V1.2521.00
178_L311_L1.2491.00
139_T143_R1.2471.00
31_P346_L1.2441.00
344_S347_Q1.2421.00
327_A330_Q1.2281.00
340_L343_S1.2211.00
77_A97_L1.2171.00
223_K227_A1.2111.00
136_V142_K1.2041.00
179_F212_A1.2021.00
165_E274_Q1.1981.00
5_M29_L1.1961.00
5_M78_H1.1901.00
306_E309_D1.1901.00
176_R254_M1.1591.00
133_A351_R1.1571.00
143_R146_D1.1531.00
224_L227_A1.1461.00
260_S302_T1.1321.00
245_I249_L1.1271.00
264_F269_Q1.1261.00
250_S274_Q1.1251.00
242_R245_I1.1241.00
322_R326_E1.1221.00
219_S222_E1.1151.00
325_K328_G1.1031.00
259_S262_E1.0981.00
308_A312_D1.0921.00
198_A202_Q1.0921.00
28_Y31_P1.0921.00
318_R321_A1.0861.00
136_V145_L1.0841.00
219_S223_K1.0831.00
191_S195_K1.0761.00
268_A286_F1.0751.00
164_E246_R1.0751.00
222_E226_A1.0741.00
280_V298_I1.0711.00
176_R207_L1.0701.00
292_H310_L1.0681.00
299_A307_A1.0641.00
337_H340_L1.0611.00
281_S299_A1.0611.00
257_F268_A1.0541.00
212_A240_L1.0531.00
284_G287_C1.0481.00
177_F252_C1.0401.00
330_Q333_F1.0381.00
276_V325_K1.0371.00
21_H266_L1.0321.00
192_Q281_S1.0291.00
102_H266_L1.0261.00
341_I344_S1.0261.00
249_L274_Q1.0251.00
192_Q195_K1.0231.00
275_G326_E1.0221.00
338_P341_I1.0191.00
192_Q302_T1.0181.00
257_F267_A1.0121.00
272_M278_T1.0111.00
137_L158_S1.0101.00
210_V251_H1.0091.00
320_K324_I1.0091.00
176_R206_D1.0051.00
255_A267_A1.0021.00
258_P307_A1.0021.00
137_L141_M0.9991.00
183_R187_E0.9911.00
225_A236_F0.9901.00
191_S260_S0.9891.00
175_R206_D0.9861.00
265_G286_F0.9861.00
343_S347_Q0.9851.00
199_I202_Q0.9831.00
326_E330_Q0.9821.00
237_L248_L0.9781.00
143_R147_K0.9751.00
200_L207_L0.9741.00
181_Y212_A0.9741.00
297_I324_I0.9731.00
309_D313_S0.9721.00
285_G288_D0.9661.00
5_M26_I0.9651.00
179_F248_L0.9651.00
191_S220_C0.9651.00
246_R250_S0.9641.00
89_L93_L0.9631.00
181_Y249_L0.9631.00
262_E265_G0.9551.00
178_L197_F0.9541.00
24_R27_S0.9511.00
341_I345_Y0.9491.00
136_V141_M0.9441.00
65_V69_N0.9411.00
67_S72_F0.9361.00
314_F324_I0.9331.00
66_L70_K0.9311.00
297_I314_F0.9311.00
16_S19_G0.9291.00
78_H102_H0.9261.00
240_L248_L0.9241.00
237_L240_L0.9241.00
165_E246_R0.9231.00
194_L225_A0.9201.00
195_K228_Y0.9191.00
97_L131_A0.9161.00
200_L311_L0.9151.00
158_S266_L0.9131.00
318_R322_R0.9091.00
144_S147_K0.9081.00
272_M328_G0.9061.00
26_I37_V0.9061.00
131_A134_L0.9041.00
77_A99_A0.9031.00
193_L258_P0.9021.00
154_T348_L0.9011.00
162_M337_H0.9001.00
279_V299_A0.8931.00
188_K262_E0.8911.00
325_K329_R0.8891.00
137_L263_P0.8861.00
180_S211_L0.8841.00
295_T328_G0.8821.00
197_F233_R0.8811.00
200_L315_L0.8811.00
268_A280_V0.8801.00
271_S276_V0.8781.00
225_A230_L0.8771.00
159_P341_I0.8741.00
207_L315_L0.8731.00
192_Q307_A0.8731.00
322_R325_K0.8671.00
24_R338_P0.8631.00
280_V290_A0.8631.00
277_L325_K0.8611.00
324_I327_A0.8601.00
300_D303_L0.8581.00
208_Y233_R0.8581.00
154_T344_S0.8531.00
272_M331_Q0.8501.00
297_I320_K0.8471.00
98_A135_I0.8461.00
21_H102_H0.8461.00
198_A201_K0.8411.00
290_A298_I0.8381.00
242_R246_R0.8351.00
268_A278_T0.8341.00
196_V308_A0.8301.00
185_V216_P0.8281.00
161_S164_E0.8271.00
200_L308_A0.8271.00
179_F249_L0.8231.00
191_S217_S0.8191.00
292_H295_T0.8131.00
180_S258_P0.8121.00
254_M314_F0.8121.00
337_H341_I0.8091.00
135_I156_I0.8081.00
272_M295_T0.8071.00
305_Q309_D0.8071.00
249_L276_V0.8051.00
279_V310_L0.8031.00
220_C223_K0.8001.00
156_I348_L0.7991.00
223_K226_A0.7951.00
90_K97_L0.7941.00
247_T251_H0.7931.00
149_A153_I0.7931.00
146_D153_I0.7921.00
173_M176_R0.7911.00
200_L205_P0.7911.00
283_S286_F0.7891.00
248_L251_H0.7831.00
188_K267_A0.7781.00
195_K198_A0.7751.00
268_A289_Y0.7751.00
256_V311_L0.7741.00
257_F286_F0.7731.00
196_V304_V0.7721.00
20_V24_R0.7711.00
343_S346_L0.7711.00
140_F143_R0.7691.00
220_C224_L0.7691.00
148_A152_K0.7671.00
331_Q336_H0.7651.00
254_M311_L0.7621.00
195_K199_I0.7621.00
161_S165_E0.7611.00
172_S208_Y0.7581.00
122_M125_R0.7581.00
22_L78_H0.7561.00
201_K205_P0.7551.00
188_K259_S0.7531.00
277_L314_F0.7531.00
347_Q351_R0.7511.00
122_M126_L0.7471.00
24_R28_Y0.7451.00
157_P344_S0.7441.00
180_S255_A0.7361.00
186_P191_S0.7351.00
88_Y92_R0.7321.00
157_P288_D0.7311.00
24_R161_S0.7311.00
96_P132_D0.7251.00
198_A230_L0.7231.00
31_P339_R0.7221.00
184_F218_L0.7211.00
126_L130_S0.7201.00
282_Q298_I0.7191.00
225_A234_V0.7161.00
98_A133_A0.7151.00
36_T40_P0.7141.00
347_Q350_E0.7111.00
279_V314_F0.7111.00
338_P342_M0.7081.00
247_T250_S0.7081.00
339_R343_S0.7061.00
102_H137_L0.7051.00
253_E321_A0.7011.00
140_F144_S0.7001.00
309_D312_D0.6991.00
76_H345_Y0.6961.00
21_H100_T0.6921.00
281_S301_F0.6871.00
156_I345_Y0.6851.00
345_Y349_Y0.6831.00
16_S183_R0.6831.00
74_L349_Y0.6811.00
287_C298_I0.6811.00
323_R326_E0.6791.00
180_S209_L0.6781.00
186_P217_S0.6781.00
7_S18_L0.6771.00
181_Y255_A0.6721.00
148_A151_K0.6711.00
157_P336_H0.6691.00
20_V23_N0.6681.00
281_S307_A0.6681.00
21_H158_S0.6681.00
186_P260_S0.6641.00
225_A228_Y0.6631.00
264_F336_H0.6631.00
305_Q308_A0.6611.00
324_I328_G0.6601.00
137_L266_L0.6601.00
182_G190_L0.6601.00
77_A83_A0.6591.00
178_L207_L0.6591.00
265_G268_A0.6571.00
213_G238_P0.6571.00
293_D313_S0.6541.00
90_K93_L0.6511.00
168_K250_S0.6471.00
269_Q336_H0.6471.00
91_Q130_S0.6471.00
292_H297_I0.6461.00
313_S316_K0.6461.00
295_T327_A0.6451.00
31_P342_M0.6451.00
74_L98_A0.6441.00
162_M333_F0.6441.00
272_M325_K0.6441.00
103_G187_E0.6421.00
78_H100_T0.6401.00
182_G188_K0.6391.00
206_D233_R0.6381.00
201_K207_L0.6361.00
118_P121_L0.6351.00
154_T157_P0.6321.00
32_H346_L0.6311.00
319_E322_R0.6291.00
197_F200_L0.6261.00
329_R332_V0.6251.00
222_E236_F0.6231.00
319_E323_R0.6211.00
176_R318_R0.6161.00
178_L315_L0.6151.00
25_L345_Y0.6151.00
21_H345_Y0.6141.00
98_A349_Y0.6121.00
314_F321_A0.6121.00
156_I344_S0.6121.00
66_L69_N0.6121.00
162_M273_E0.6111.00
196_V311_L0.6111.00
7_S22_L0.6081.00
290_A295_T0.6081.00
256_V307_A0.6041.00
125_R129_E0.6041.00
190_L217_S0.6031.00
90_K132_D0.6021.00
257_F265_G0.6021.00
65_V68_H0.6001.00
59_F63_R0.5971.00
328_G331_Q0.5961.00
299_A306_E0.5951.00
140_F287_C0.5941.00
75_I90_K0.5921.00
248_L252_C0.5921.00
342_M346_L0.5901.00
348_L351_R0.5891.00
79_D82_T0.5851.00
193_L197_F0.5851.00
176_R179_F0.5841.00
26_I35_I0.5821.00
205_P316_K0.5811.00
5_M35_I0.5811.00
77_A86_A0.5811.00
179_F255_A0.5811.00
194_L234_V0.5761.00
67_S70_K0.5761.00
72_F95_L0.5761.00
326_E329_R0.5741.00
255_A278_T0.5741.00
9_E19_G0.5731.00
177_F248_L0.5731.00
166_K250_S0.5711.00
317_D321_A0.5701.00
27_S30_N0.5681.00
217_S221_Y0.5671.00
254_M279_V0.5651.00
136_V155_V0.5651.00
189_G258_P0.5631.00
54_I57_A0.5611.00
100_T345_Y0.5601.00
33_I350_E0.5601.00
225_A231_K0.5591.00
212_A245_I0.5581.00
150_H153_I0.5571.00
97_L132_D0.5531.00
100_T135_I0.5531.00
192_Q196_V0.5531.00
191_S221_Y0.5521.00
179_F276_V0.5501.00
32_H35_I0.5481.00
327_A331_Q0.5471.00
196_V200_L0.5461.00
141_M144_S0.5461.00
189_G302_T0.5431.00
30_N339_R0.5431.00
215_G218_L0.5431.00
176_R321_A0.5421.00
69_N72_F0.5421.00
240_L245_I0.5381.00
138_S141_M0.5371.00
179_F210_V0.5361.00
194_L221_Y0.5361.00
5_M76_H0.5361.00
253_E318_R0.5361.00
184_F190_L0.5361.00
271_S278_T0.5351.00
20_V242_R0.5351.00
189_G281_S0.5341.00
174_N206_D0.5341.00
209_L234_V0.5341.00
214_E239_F0.5321.00
283_S287_C0.5301.00
283_S301_F0.5291.00
146_D149_A0.5291.00
10_H23_N0.5281.00
142_K150_H0.5281.00
186_P220_C0.5251.00
249_L267_A0.5251.00
157_P341_I0.5251.00
75_I95_L0.5251.00
139_T157_P0.5251.00
321_A324_I0.5221.00
265_G269_Q0.5201.00
18_L79_D0.5201.00
221_Y236_F0.5201.00
24_R266_L0.5201.00
258_P281_S0.5171.00
141_M263_P0.5171.00
196_V256_V0.5151.00
277_L321_A0.5131.00
157_P264_F0.5121.00
267_A271_S0.5111.00
166_K169_I0.5101.00
102_H158_S0.5091.00
105_E108_R0.5091.00
335_L340_L0.5081.00
272_M332_V0.5081.00
38_F66_L0.5061.00
269_Q332_V0.5051.00
60_T63_R0.5041.00
21_H78_H0.5031.00
101_I141_M0.5031.00
282_Q301_F0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2r60A 1 0.9833 100 0.151 Contact Map
4n9wA 1 0.9276 100 0.154 Contact Map
3c48A 2 0.9638 100 0.166 Contact Map
3froA 3 0.9833 100 0.182 Contact Map
1rzuA 1 0.9694 100 0.186 Contact Map
2x6qA 1 0.9276 100 0.193 Contact Map
3okpA 1 0.9526 100 0.195 Contact Map
2qzsA 1 0.961 100 0.201 Contact Map
3oy2A 2 0.9415 100 0.204 Contact Map
2jjmA 4 0.9164 100 0.208 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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