GREMLIN Database
YQGF - Uncharacterized protein YqgF
UniProt: P54488 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 716 (598)
Sequences: 8183 (6158)
Seq/√Len: 251.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
199_Y209_E4.7061.00
190_D200_I4.1021.00
251_E255_S4.0851.00
244_G254_P3.8001.00
250_N253_L3.7011.00
558_D567_A3.5741.00
535_A656_S3.4951.00
643_V656_S3.3671.00
98_T102_R3.2871.00
356_M655_I3.2731.00
442_V452_S3.1891.00
356_M680_V3.1281.00
244_G251_E2.9971.00
125_K128_Y2.9741.00
546_Y579_K2.9611.00
233_Y237_N2.7541.00
333_I352_A2.7071.00
126_K130_I2.7001.00
591_Q645_Y2.6781.00
127_D130_I2.5971.00
410_T483_T2.5321.00
75_R322_D2.4351.00
102_R248_S2.4281.00
73_Y316_D2.4201.00
100_E189_M2.4021.00
363_E551_Q2.3971.00
354_V680_V2.3861.00
425_Y430_K2.3841.00
168_T171_Q2.3721.00
318_V555_E2.3511.00
445_Q592_A2.3321.00
359_P654_A2.3121.00
254_P258_L2.3021.00
113_I170_K2.2681.00
98_T101_Q2.2441.00
358_D361_N2.2421.00
190_D201_K2.2331.00
92_T95_K2.2181.00
93_R101_Q2.2061.00
363_E554_K2.1881.00
446_T450_K2.1791.00
208_K260_H2.1701.00
74_D78_N2.1611.00
71_K79_A2.1561.00
364_V552_L2.1471.00
536_Q550_P2.1311.00
107_K238_L2.1301.00
207_A249_S2.1091.00
335_K679_E2.1041.00
536_Q547_R2.0521.00
445_Q596_R2.0501.00
241_S258_L2.0331.00
418_V441_P2.0171.00
111_D119_K1.9981.00
329_V354_V1.9951.00
93_R174_E1.9821.00
99_Q102_R1.9461.00
365_L653_I1.9361.00
93_R170_K1.9311.00
616_A642_L1.9261.00
99_Q210_M1.9111.00
284_L287_G1.9091.00
327_K331_K1.9051.00
358_D365_L1.9041.00
97_T201_K1.8791.00
110_S242_V1.8751.00
592_A595_R1.8611.00
101_Q170_K1.8391.00
544_G588_E1.8381.00
399_V488_F1.8311.00
409_Q490_Q1.8201.00
387_G662_T1.7981.00
242_V245_S1.7961.00
186_K195_L1.7951.00
406_T487_Y1.7851.00
486_N490_Q1.7821.00
541_I590_V1.7771.00
283_S286_Q1.7771.00
125_K130_I1.7741.00
402_A537_Y1.7651.00
316_D557_R1.7611.00
439_L452_S1.7601.00
212_V232_E1.7581.00
685_F688_K1.7521.00
328_S683_K1.7491.00
678_R682_D1.7451.00
395_M529_Y1.7441.00
446_T449_E1.7361.00
615_A645_Y1.7201.00
460_A484_F1.7191.00
531_P656_S1.7161.00
95_K203_E1.7111.00
534_L643_V1.7091.00
73_Y318_V1.7071.00
434_K668_Q1.6981.00
355_V531_P1.6971.00
107_K242_V1.6971.00
110_S246_V1.6971.00
100_E210_M1.6891.00
325_L684_Y1.6821.00
357_M535_A1.6801.00
115_V164_L1.6761.00
415_L589_E1.6731.00
106_A248_S1.6671.00
464_G481_F1.6671.00
240_R254_P1.6631.00
219_E222_G1.6561.00
449_E596_R1.6551.00
358_D363_E1.6541.00
207_A257_L1.6521.00
281_Y285_L1.6371.00
71_K316_D1.6361.00
241_S254_P1.6341.00
419_F462_A1.6191.00
401_G541_I1.6111.00
75_R365_L1.6031.00
420_K441_P1.6001.00
242_V246_V1.5851.00
355_V532_L1.5821.00
104_K214_S1.5811.00
483_T486_N1.5531.00
415_L593_G1.5501.00
677_G681_M1.5451.00
106_A246_V1.5441.00
104_K182_I1.5331.00
683_K686_E1.5211.00
408_L593_G1.5171.00
613_K690_K1.5141.00
325_L365_L1.5101.00
331_K335_K1.5061.00
354_V655_I1.5031.00
447_A455_F1.4991.00
200_I204_D1.4841.00
228_D231_R1.4811.00
103_L243_L1.4761.00
330_E368_A1.4721.00
105_I113_I1.4671.00
568_V571_S1.4541.00
328_S332_I1.4501.00
596_R600_K1.4501.00
78_N323_I1.4441.00
598_A614_P1.4421.00
244_G249_S1.4341.00
405_L586_Y1.4331.00
194_A198_Q1.4291.00
409_Q586_Y1.4271.00
104_K217_L1.4181.00
141_I163_Q1.4181.00
200_I203_E1.4171.00
100_E104_K1.4141.00
555_E571_S1.4021.00
659_V676_I1.4011.00
181_Q185_I1.3991.00
539_S654_A1.3891.00
422_E458_K1.3811.00
614_P646_A1.3771.00
487_Y491_F1.3671.00
557_R568_V1.3651.00
357_M654_A1.3621.00
205_V210_M1.3561.00
460_A481_F1.3551.00
280_Q285_L1.3491.00
652_E691_Q1.3481.00
180_M217_L1.3391.00
101_Q113_I1.3371.00
230_E234_P1.3351.00
93_R113_I1.3351.00
79_A82_T1.3251.00
354_V657_V1.3221.00
403_T522_A1.3191.00
91_Y96_S1.3151.00
398_A534_L1.3111.00
454_V458_K1.3061.00
251_E254_P1.3051.00
432_G436_W1.3051.00
281_Y320_T1.3021.00
385_A391_S1.2981.00
171_Q174_E1.2951.00
544_G584_S1.2951.00
405_L582_M1.2921.00
331_K683_K1.2891.00
167_I175_L1.2851.00
182_I189_M1.2831.00
549_K575_E1.2821.00
318_V557_R1.2821.00
449_E600_K1.2811.00
409_Q487_Y1.2791.00
284_L288_Q1.2791.00
579_K584_S1.2721.00
255_S259_D1.2711.00
282_E285_L1.2661.00
111_D114_K1.2631.00
241_S245_S1.2631.00
93_R96_S1.2621.00
655_I680_V1.2621.00
206_S260_H1.2601.00
332_I679_E1.2561.00
409_Q583_K1.2551.00
583_K586_Y1.2471.00
252_G256_N1.2401.00
444_I459_T1.2381.00
405_L541_I1.2371.00
96_S100_E1.2311.00
531_P535_A1.2311.00
582_M587_I1.2231.00
229_W233_Y1.2221.00
442_V455_F1.2201.00
408_L589_E1.2181.00
452_S455_F1.2061.00
244_G258_L1.2051.00
150_E154_I1.2041.00
249_S254_P1.2031.00
231_R234_P1.2011.00
280_Q283_S1.2001.00
402_A488_F1.1971.00
184_A224_D1.1951.00
336_K679_E1.1901.00
386_L389_M1.1841.00
329_V680_V1.1831.00
330_E334_E1.1801.00
461_I519_L1.1771.00
405_L487_Y1.1731.00
543_N548_M1.1711.00
443_G446_T1.1681.00
493_L529_Y1.1631.00
419_F455_F1.1621.00
315_K569_V1.1621.00
41_G45_I1.1611.00
126_K129_W1.1611.00
495_V533_E1.1601.00
491_F540_T1.1591.00
560_N567_A1.1521.00
591_Q594_F1.1481.00
595_R599_T1.1461.00
222_G231_R1.1431.00
124_D127_D1.1411.00
540_T547_R1.1411.00
199_Y204_D1.1371.00
414_N417_T1.1351.00
644_A677_G1.1341.00
325_L366_T1.1341.00
598_A616_A1.1331.00
287_G290_A1.1221.00
124_D128_Y1.1221.00
255_S258_L1.1201.00
360_R652_E1.1191.00
237_N258_L1.1181.00
435_S439_L1.1181.00
598_A642_L1.1151.00
125_K129_W1.1141.00
367_M386_L1.1141.00
541_I645_Y1.1121.00
92_T174_E1.1111.00
253_L256_N1.1091.00
639_N658_V1.1081.00
99_Q253_L1.1051.00
177_D189_M1.1041.00
355_V367_M1.0981.00
356_M653_I1.0971.00
133_R142_S1.0951.00
208_K257_L1.0941.00
591_Q615_A1.0941.00
241_S244_G1.0921.00
306_K309_S1.0921.00
333_I368_A1.0831.00
359_P653_I1.0821.00
444_I593_G1.0711.00
595_R613_K1.0711.00
398_A643_V1.0691.00
74_D323_I1.0681.00
91_Y201_K1.0671.00
278_E281_Y1.0671.00
491_F582_M1.0611.00
40_L43_K1.0601.00
162_L166_R1.0581.00
256_N260_H1.0541.00
99_Q207_A1.0491.00
233_Y236_K1.0481.00
429_D457_F1.0481.00
456_M459_T1.0471.00
542_A645_Y1.0431.00
162_L165_K1.0411.00
482_D517_F1.0401.00
282_E286_Q1.0381.00
283_S288_Q1.0351.00
588_E696_T1.0351.00
207_A240_R1.0291.00
614_P677_G1.0281.00
653_I684_Y1.0261.00
329_V368_A1.0241.00
413_I462_A1.0211.00
75_R363_E1.0181.00
597_V603_A1.0161.00
118_K157_D1.0161.00
393_Y639_N1.0151.00
279_Y285_L1.0121.00
460_A522_A1.0121.00
151_D155_S1.0111.00
408_L590_V1.0081.00
487_Y490_Q1.0081.00
487_Y582_M1.0061.00
325_L680_V1.0041.00
482_D486_N1.0041.00
547_R578_N1.0031.00
119_K122_E0.9991.00
402_A491_F0.9971.00
448_L456_M0.9941.00
283_S287_G0.9911.00
285_L289_K0.9871.00
96_S101_Q0.9871.00
281_Y284_L0.9831.00
647_P652_E0.9831.00
181_Q187_R0.9821.00
111_D115_V0.9811.00
442_V447_A0.9801.00
655_I681_M0.9791.00
644_A681_M0.9781.00
558_D566_G0.9781.00
367_M552_L0.9761.00
111_D121_T0.9751.00
329_V366_T0.9731.00
208_K236_K0.9711.00
280_Q286_Q0.9701.00
541_I591_Q0.9691.00
485_R489_S0.9671.00
323_I327_K0.9671.00
394_A621_A0.9651.00
542_A615_A0.9641.00
142_S146_R0.9631.00
70_G317_L0.9631.00
100_E177_D0.9621.00
318_V554_K0.9621.00
72_I80_I0.9601.00
357_M550_P0.9601.00
460_A521_F0.9581.00
419_F444_I0.9571.00
413_I417_T0.9551.00
77_F554_K0.9501.00
309_S313_A0.9501.00
333_I354_V0.9501.00
109_L115_V0.9491.00
282_E287_G0.9491.00
105_I248_S0.9481.00
587_I591_Q0.9471.00
73_Y79_A0.9461.00
424_L458_K0.9451.00
553_V556_V0.9451.00
520_D525_Q0.9431.00
140_L175_L0.9411.00
435_S452_S0.9411.00
457_F523_I0.9361.00
359_P542_A0.9361.00
90_T174_E0.9351.00
640_T673_T0.9341.00
144_K147_Q0.9341.00
659_V673_T0.9331.00
252_G255_S0.9321.00
439_L442_V0.9321.00
670_Y674_N0.9321.00
555_E568_V0.9281.00
279_Y282_E0.9281.00
120_V123_R0.9281.00
408_L586_Y0.9271.00
194_A200_I0.9271.00
320_T363_E0.9271.00
129_W148_Q0.9261.00
395_M399_V0.9261.00
352_A676_I0.9261.00
30_F34_T0.9231.00
124_D130_I0.9211.00
413_I459_T0.9211.00
403_T484_F0.9191.00
463_V483_T0.9171.00
405_L491_F0.9171.00
420_K458_K0.9171.00
39_E45_I0.9161.00
413_I444_I0.9151.00
385_A390_T0.9111.00
657_V676_I0.9101.00
596_R599_T0.9101.00
609_S678_R0.9101.00
41_G44_Q0.9101.00
42_I46_V0.9081.00
551_Q572_V0.9081.00
280_Q284_L0.9071.00
123_R138_K0.9071.00
584_S588_E0.9051.00
406_T410_T0.9031.00
44_Q47_Q0.8991.00
419_F459_T0.8991.00
407_G459_T0.8981.00
320_T551_Q0.8971.00
612_Y652_E0.8951.00
548_M576_V0.8941.00
355_V535_A0.8911.00
322_D325_L0.8911.00
351_R387_G0.8901.00
101_Q173_N0.8901.00
463_V484_F0.8871.00
454_V457_F0.8871.00
215_E232_E0.8831.00
612_Y689_S0.8831.00
26_F30_F0.8801.00
189_M213_V0.8791.00
230_E233_Y0.8771.00
652_E688_K0.8771.00
640_T667_N0.8741.00
530_T533_E0.8681.00
289_K293_E0.8650.99
421_D439_L0.8630.99
486_N489_S0.8610.99
405_L590_V0.8560.99
104_K177_D0.8560.99
324_D687_L0.8560.99
244_G255_S0.8560.99
102_R113_I0.8560.99
39_E42_I0.8540.99
78_N324_D0.8540.99
357_M539_S0.8530.99
39_E43_K0.8530.99
282_E288_Q0.8520.99
288_Q291_K0.8510.99
97_T100_E0.8500.99
34_T41_G0.8480.99
531_P641_T0.8460.99
285_L288_Q0.8420.99
386_L390_T0.8420.99
438_N454_V0.8410.99
442_V446_T0.8410.99
190_D194_A0.8400.99
43_K47_Q0.8390.99
302_V305_T0.8370.99
23_N27_L0.8360.99
485_R517_F0.8350.99
610_A613_K0.8350.99
613_K692_D0.8350.99
34_T38_V0.8350.99
320_T554_K0.8330.99
280_Q287_G0.8320.99
693_K696_T0.8310.99
24_I28_A0.8310.99
325_L356_M0.8280.99
328_S331_K0.8280.99
600_K604_A0.8240.99
30_F39_E0.8230.99
448_L593_G0.8220.99
657_V677_G0.8190.99
372_I375_E0.8180.99
212_V215_E0.8160.99
184_A195_L0.8150.99
29_A36_I0.8150.99
281_Y287_G0.8140.99
679_E683_K0.8120.99
55_A58_Q0.8110.99
534_L641_T0.8110.99
289_K292_V0.8100.99
93_R173_N0.8100.99
529_Y534_L0.8090.99
103_L214_S0.8070.99
154_I158_D0.8060.99
647_P693_K0.8060.99
395_M526_Y0.8030.99
625_Y664_I0.8020.99
218_D223_V0.8020.99
535_A643_V0.8010.99
124_D129_W0.7980.99
201_K205_V0.7950.99
405_L587_I0.7940.99
284_L290_A0.7940.99
76_N323_I0.7940.99
116_D120_V0.7920.99
107_K235_Y0.7920.99
460_A519_L0.7870.99
277_L280_Q0.7860.99
437_Q440_G0.7850.99
216_H219_E0.7830.99
458_K462_A0.7830.99
587_I590_V0.7820.99
37_I44_Q0.7820.99
278_E282_E0.7810.99
45_I48_G0.7810.99
401_G594_F0.7780.99
640_T669_R0.7760.99
107_K218_D0.7760.99
485_R521_F0.7740.99
595_R692_D0.7730.99
40_L44_Q0.7720.99
71_K82_T0.7720.99
421_D440_G0.7720.99
336_K676_I0.7710.99
364_V532_L0.7700.99
395_M525_Q0.7660.99
588_E695_G0.7640.99
359_P539_S0.7610.99
483_T487_Y0.7610.99
353_F531_P0.7590.99
89_I190_D0.7580.99
332_I676_I0.7560.99
536_Q549_K0.7550.99
439_L450_K0.7510.99
329_V356_M0.7490.99
646_A652_E0.7470.99
598_A603_A0.7470.99
48_G52_K0.7460.98
582_M586_Y0.7450.98
206_S210_M0.7420.98
249_S253_L0.7410.98
24_I27_L0.7410.98
439_L446_T0.7390.98
538_V643_V0.7370.98
37_I45_I0.7360.98
361_N551_Q0.7340.98
37_I41_G0.7320.98
640_T672_I0.7320.98
145_E149_V0.7310.98
56_N59_E0.7310.98
612_Y685_F0.7290.98
335_K339_A0.7290.98
219_E223_V0.7290.98
579_K582_M0.7280.98
594_F645_Y0.7280.98
286_Q289_K0.7280.98
278_E283_S0.7270.98
43_K46_V0.7270.98
136_E180_M0.7270.98
464_G483_T0.7270.98
680_V684_Y0.7270.98
481_F517_F0.7260.98
28_A35_W0.7250.98
218_D222_G0.7240.98
207_A210_M0.7230.98
105_I173_N0.7230.98
417_T462_A0.7230.98
423_P438_N0.7220.98
399_V403_T0.7210.98
491_F537_Y0.7190.98
277_L281_Y0.7190.98
253_L257_L0.7190.98
89_I194_A0.7180.98
91_Y190_D0.7180.98
494_G533_E0.7170.98
607_L610_A0.7160.98
421_D438_N0.7140.98
23_N26_F0.7130.98
325_L328_S0.7120.98
284_L552_L0.7120.98
31_V38_V0.7100.98
120_V161_Q0.7100.98
355_V388_A0.7090.98
402_A534_L0.7090.98
138_K156_D0.7080.98
137_A164_L0.7080.98
97_T210_M0.7040.98
332_I683_K0.7030.98
273_G276_Y0.7020.98
392_S528_T0.7010.98
36_I39_E0.7010.98
104_K189_M0.6990.98
490_Q578_N0.6990.98
32_I36_I0.6990.98
419_F458_K0.6950.98
605_G675_E0.6950.98
397_S400_K0.6940.98
305_T308_V0.6940.98
586_Y590_V0.6930.98
286_Q290_A0.6910.98
38_V42_I0.6910.98
26_F44_Q0.6900.98
144_K148_Q0.6900.98
541_I582_M0.6890.97
23_N30_F0.6860.97
597_V616_A0.6860.97
639_N660_P0.6820.97
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300_G304_G0.5540.92
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588_E591_Q0.5530.92
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608_A611_S0.5410.91
669_R673_T0.5410.91
603_A607_L0.5400.91
359_P647_P0.5400.91
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215_E238_L0.5380.91
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393_Y660_P0.5340.90
281_Y288_Q0.5340.90
418_V443_G0.5330.90
100_E214_S0.5320.90
152_K156_D0.5320.90
198_Q265_G0.5310.90
92_T96_S0.5310.90
76_N324_D0.5310.90
189_M201_K0.5290.90
181_Q184_A0.5290.90
27_L38_V0.5290.90
129_W150_E0.5290.90
547_R550_P0.5290.90
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33_F36_I0.5270.90
88_A314_G0.5270.90
410_T413_I0.5260.90
74_D80_I0.5250.90
190_D203_E0.5250.90
161_Q165_K0.5250.90
351_R662_T0.5250.90
147_Q152_K0.5240.89
147_Q151_D0.5240.89
54_Q57_K0.5240.89
30_F37_I0.5240.89
105_I119_K0.5220.89
155_S158_D0.5220.89
590_V594_F0.5220.89
50_D53_N0.5200.89
30_F48_G0.5200.89
583_K587_I0.5200.89
609_S612_Y0.5190.89
554_K557_R0.5180.89
373_K384_Y0.5170.89
399_V402_A0.5170.89
640_T659_V0.5160.89
326_Q367_M0.5160.89
34_T37_I0.5150.89
38_V41_G0.5130.88
212_V216_H0.5130.88
538_V654_A0.5130.88
311_G315_K0.5130.88
349_L665_D0.5120.88
426_I519_L0.5120.88
277_L282_E0.5110.88
29_A39_E0.5110.88
87_N191_S0.5100.88
233_Y262_L0.5100.88
416_N445_Q0.5100.88
288_Q292_V0.5090.88
218_D238_L0.5080.88
276_Y280_Q0.5080.88
280_Q288_Q0.5080.88
132_T137_A0.5080.88
429_D519_L0.5050.88
532_L535_A0.5040.88
183_L196_T0.5030.88
497_T533_E0.5030.88
272_V276_Y0.5010.87
577_L580_V0.5010.87
39_E44_Q0.5010.87
361_N548_M0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4oonA 1 0.5237 100 0.215 Contact Map
3udfA 2 0.6858 100 0.237 Contact Map
2jchA 1 0.5321 100 0.244 Contact Map
3vmaA 1 0.8478 100 0.26 Contact Map
2olvA 1 0.8142 100 0.265 Contact Map
3zg9B 1 0.6243 100 0.406 Contact Map
2wadA 1 0.8226 100 0.423 Contact Map
3vskA 2 0.8561 100 0.454 Contact Map
4ye5A 1 0.7528 100 0.464 Contact Map
3equA 1 0.5936 100 0.481 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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