GREMLIN Database
YQFC - Uncharacterized protein YqfC
UniProt: P54468 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 93 (87)
Sequences: 345 (261)
Seq/√Len: 28.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_L62_C3.7621.00
27_P60_G3.3621.00
29_I37_I3.0011.00
21_D78_E2.3970.99
45_L53_V2.2340.98
8_M46_L1.8660.95
46_L56_M1.8430.94
31_M88_V1.8210.94
39_I55_L1.7140.92
13_T23_M1.6260.89
10_A14_R1.6090.89
67_K86_D1.5310.86
71_I90_Y1.4870.85
46_L86_D1.4570.83
10_A53_V1.4550.83
25_D58_K1.4510.83
47_L54_R1.4270.82
67_K87_V1.4120.81
39_I81_L1.4010.81
69_F81_L1.3620.79
72_K76_P1.3210.77
71_I74_I1.3170.76
31_M85_I1.3040.76
9_K89_R1.2890.75
25_D74_I1.2250.71
67_K84_T1.2210.71
45_L79_I1.2090.70
10_A34_R1.2050.70
69_F79_I1.2030.70
76_P81_L1.1990.69
75_L78_E1.1930.69
7_R89_R1.1790.68
24_M67_K1.1700.67
21_D73_A1.1510.66
24_M37_I1.1400.65
55_L59_Q1.1350.65
20_P73_A1.1290.65
53_V87_V1.1240.64
5_K9_K1.1080.63
17_E25_D1.0980.62
64_I87_V1.0950.62
56_M59_Q1.0920.62
81_L91_V1.0840.61
29_I88_V1.0620.60
65_S89_R1.0580.59
25_D42_H1.0290.57
18_I77_E1.0270.57
22_V36_H1.0220.57
56_M79_I1.0130.56
46_L84_T1.0110.56
13_T39_I1.0080.56
14_R20_P0.9830.54
45_L74_I0.9700.53
71_I75_L0.9580.52
23_M64_I0.9570.52
48_F77_E0.9330.50
72_K82_E0.9310.50
45_L50_E0.9250.49
37_I69_F0.9160.49
68_N84_T0.9080.48
26_L42_H0.9010.47
34_R50_E0.8970.47
56_M61_Q0.8820.46
65_S77_E0.8810.46
34_R84_T0.8780.46
39_I86_D0.8680.45
78_E85_I0.8660.45
11_W18_I0.8610.44
5_K17_E0.8560.44
46_L87_V0.8440.43
28_R79_I0.8390.43
17_E48_F0.8250.42
42_H75_L0.8250.42
8_M51_N0.8190.41
5_K10_A0.8140.41
54_R61_Q0.8010.40
63_I89_R0.7970.40
53_V81_L0.7920.39
32_V74_I0.7860.39
30_T38_Y0.7610.37
36_H45_L0.7470.36
6_N18_I0.7460.36
36_H82_E0.7430.36
32_V42_H0.7390.35
23_M51_N0.7310.35
9_K71_I0.7120.34
37_I84_T0.7070.33
43_R91_V0.7020.33
37_I64_I0.7010.33
16_L23_M0.7000.33
88_V91_V0.6950.32
5_K86_D0.6940.32
14_R32_V0.6790.31
32_V55_L0.6730.31
57_L60_G0.6720.31
29_I35_L0.6700.31
33_G69_F0.6700.31
36_H70_V0.6700.31
26_L44_G0.6650.30
72_K80_L0.6640.30
54_R89_R0.6570.30
49_S73_A0.6540.30
15_A36_H0.6420.29
26_L71_I0.6410.29
25_D37_I0.6360.29
12_L55_L0.6230.28
7_R48_F0.6120.27
31_M63_I0.5980.26
18_I33_G0.5950.26
31_M91_V0.5940.26
15_A69_F0.5850.26
36_H69_F0.5780.25
23_M88_V0.5770.25
61_Q74_I0.5700.25
65_S86_D0.5670.25
8_M11_W0.5600.24
23_M68_N0.5600.24
17_E54_R0.5540.24
37_I51_N0.5490.23
19_P44_G0.5490.23
48_F74_I0.5440.23
11_W28_R0.5410.23
14_R52_E0.5340.23
17_E27_P0.5340.23
8_M20_P0.5220.22
30_T35_L0.5180.22
50_E67_K0.5100.21
66_G83_G0.5080.21
48_F85_I0.5010.21
12_L16_L0.5000.21
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2ks0A 2 0.6237 99.5 0.518 Contact Map
3rceA 1 0.9785 12.8 0.916 Contact Map
3u1kA 3 0.7957 7.7 0.924 Contact Map
2pmpA 3 0.5269 6.9 0.926 Contact Map
4mnoA 1 0.7957 6.5 0.927 Contact Map
4c8eA 3 0.5484 6.3 0.927 Contact Map
2ekfA 1 0.5161 5.6 0.929 Contact Map
1k8fA 2 0.6022 4.7 0.931 Contact Map
3aagA 1 0.9032 4.7 0.931 Contact Map
3re3A 5 0.5161 4.6 0.932 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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