GREMLIN Database
YQEG - Uncharacterized protein YqeG
UniProt: P54452 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 172 (159)
Sequences: 1287 (996)
Seq/√Len: 78.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
127_G134_T6.5981.00
99_F126_G3.9431.00
29_K112_D3.4321.00
9_D128_N3.4091.00
30_G108_L3.3241.00
77_K81_E3.0521.00
108_L113_C3.0191.00
30_G106_M2.5551.00
109_K112_D2.4491.00
28_V114_V2.3471.00
96_G129_R2.2661.00
103_V113_C2.2141.00
56_E60_E2.2041.00
55_F65_V2.0971.00
24_K29_K2.0911.00
35_L67_I1.9641.00
73_E77_K1.9511.00
20_P58_M1.8821.00
12_V18_I1.8801.00
114_V135_I1.8401.00
20_P63_I1.7661.00
6_F125_L1.6791.00
99_F115_V1.6211.00
150_F154_V1.6201.00
19_T22_K1.6011.00
56_E59_K1.6011.00
71_N76_V1.5941.00
13_K138_V1.5891.00
49_P53_E1.5851.00
31_I114_V1.5380.99
67_I80_S1.5370.99
10_E133_H1.5190.99
115_V132_Y1.5000.99
97_K101_R1.4620.99
41_E44_R1.4610.99
124_V134_T1.4610.99
101_R105_N1.4450.99
121_L154_V1.4340.99
31_I63_I1.4260.99
47_A79_F1.4050.99
40_V79_F1.3750.99
64_K106_M1.3720.99
33_T54_W1.3690.99
22_K26_R1.3500.98
9_D133_H1.3470.98
114_V133_H1.3310.98
33_T65_V1.3300.98
30_G113_C1.3020.98
65_V85_I1.2780.98
148_T151_N1.2720.98
102_A106_M1.2720.98
144_D148_T1.2640.98
148_T152_R1.2490.97
145_G148_T1.2190.97
20_P54_W1.2160.97
57_E60_E1.1620.96
21_E57_E1.1600.96
42_W148_T1.1410.96
110_K131_G1.1350.96
96_G130_N1.1320.96
32_I106_M1.1270.95
24_K61_H1.1250.95
15_I51_L1.1220.95
121_L151_N1.1140.95
102_A126_G1.0890.94
125_L129_R1.0860.94
15_I20_P1.0810.94
141_A144_D1.0570.94
32_I115_V1.0500.93
41_E141_A1.0370.93
119_Q148_T1.0300.93
103_V110_K1.0280.93
128_N134_T1.0120.92
23_L114_V1.0100.92
22_K25_E1.0070.92
14_N17_H0.9980.91
57_E61_H0.9920.91
80_S87_F0.9910.91
52_I56_E0.9840.91
66_T106_M0.9710.90
33_T116_I0.9710.90
52_I82_P0.9700.90
16_F51_L0.9640.90
37_N76_V0.9420.89
32_I68_V0.9330.88
12_V135_I0.9280.88
13_K17_H0.9220.88
21_E25_E0.9200.88
153_Q157_R0.9020.87
40_V47_A0.8980.86
71_N91_A0.8930.86
19_T63_I0.8700.85
53_E57_E0.8670.84
73_E89_Y0.8640.84
76_V80_S0.8640.84
88_I98_A0.8600.84
73_E90_K0.8490.83
86_P105_N0.8460.83
103_V112_D0.8450.83
20_P33_T0.8430.83
10_E135_I0.8430.83
127_G133_H0.8410.83
136_L140_V0.8370.82
7_L162_L0.8350.82
38_T55_F0.8330.82
49_P60_E0.8300.82
58_M61_H0.8270.82
49_P52_I0.8120.80
158_I162_L0.8080.80
92_R97_K0.8070.80
144_D147_I0.8050.80
144_D152_R0.8000.79
95_M129_R0.7990.79
119_Q152_R0.7930.79
10_E22_K0.7920.79
100_N130_N0.7910.79
43_D144_D0.7900.78
64_K86_P0.7900.78
18_I113_C0.7780.77
120_L136_L0.7740.77
144_D151_N0.7700.77
75_R79_F0.7650.76
16_F50_R0.7630.76
31_I58_M0.7610.76
29_K64_K0.7600.76
68_V99_F0.7510.75
115_V126_G0.7500.75
35_L99_F0.7490.75
103_V108_L0.7450.74
18_I135_I0.7430.74
160_S163_K0.7410.74
92_R95_M0.7410.74
37_N152_R0.7280.73
151_N155_E0.7200.72
90_K95_M0.7180.72
56_E61_H0.7170.71
68_V126_G0.7170.71
157_R161_A0.7160.71
98_A127_G0.7050.70
25_E163_K0.7050.70
96_G100_N0.7030.70
6_F158_I0.6960.69
10_E114_V0.6940.69
88_I102_A0.6910.69
152_R155_E0.6870.68
153_Q156_R0.6850.68
108_L112_D0.6820.68
121_L162_L0.6820.68
37_N119_Q0.6790.67
110_K132_Y0.6790.67
6_F121_L0.6770.67
151_N162_L0.6750.67
42_W71_N0.6670.66
28_V133_H0.6670.66
66_T88_I0.6650.66
53_E56_E0.6620.65
136_L139_P0.6620.65
109_K113_C0.6570.65
26_R101_R0.6530.64
18_I116_I0.6510.64
72_N90_K0.6460.63
26_R133_H0.6460.63
35_L75_R0.6450.63
68_V130_N0.6390.63
68_V102_A0.6330.62
68_V91_A0.6330.62
35_L80_S0.6320.62
71_N75_R0.6290.61
62_G119_Q0.6280.61
110_K130_N0.6210.60
115_V130_N0.6200.60
59_K85_I0.6150.60
59_K65_V0.6090.59
55_F59_K0.6080.59
42_W143_S0.6080.59
149_R158_I0.6010.58
75_R137_V0.5990.58
66_T105_N0.5970.57
47_A83_L0.5960.57
21_E59_K0.5910.57
24_K28_V0.5910.57
16_F55_F0.5910.57
37_N148_T0.5890.56
35_L151_N0.5890.56
5_F129_R0.5860.56
31_I135_I0.5860.56
44_R74_R0.5840.56
35_L79_F0.5840.56
25_E107_E0.5840.56
81_E100_N0.5810.55
146_F149_R0.5760.55
42_W145_G0.5740.54
72_N96_G0.5720.54
147_I162_L0.5720.54
147_I150_F0.5680.54
67_I150_F0.5660.53
76_V90_K0.5650.53
113_C161_A0.5640.53
11_F163_K0.5600.53
157_R160_S0.5570.52
18_I129_R0.5550.52
73_E87_F0.5550.52
55_F85_I0.5540.52
116_I135_I0.5540.52
144_D155_E0.5540.52
81_E84_G0.5520.52
107_E113_C0.5520.52
52_I104_R0.5500.51
26_R132_Y0.5500.51
41_E48_T0.5500.51
27_N112_D0.5490.51
37_N144_D0.5490.51
47_A158_I0.5470.51
88_I91_A0.5460.51
31_I61_H0.5460.51
98_A101_R0.5410.50
67_I149_R0.5360.50
27_N47_A0.5340.49
78_L81_E0.5260.48
77_K87_F0.5250.48
45_P78_L0.5230.48
62_G112_D0.5220.48
85_I163_K0.5220.48
11_F138_V0.5210.48
29_K56_E0.5160.47
128_N135_I0.5150.47
42_W149_R0.5130.47
28_V63_I0.5120.47
32_I132_Y0.5120.47
24_K116_I0.5060.46
20_P61_H0.5060.46
29_K74_R0.5050.46
5_F125_L0.5040.46
46_N153_Q0.5030.45
76_V87_F0.5030.45
23_L31_I0.5030.45
72_N92_R0.5020.45
43_D71_N0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3slrA 2 0.9302 99.9 0.564 Contact Map
2hhlA 1 0.907 99.9 0.625 Contact Map
3ib6A 4 0.8023 99.8 0.662 Contact Map
3l8hA 1 0.7965 99.8 0.662 Contact Map
2pr7A 1 0.7442 99.8 0.663 Contact Map
3n1uA 3 0.8953 99.8 0.667 Contact Map
3ij5A 4 0.9535 99.7 0.67 Contact Map
3n07A 3 0.9186 99.7 0.675 Contact Map
2p9jA 5 0.8314 99.7 0.677 Contact Map
2r8eA 5 0.9012 99.7 0.679 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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