YRKQ - BACSU - GREMLIN Contacts

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YRKQ - Sensor histidine kinase YrkQ

UniProt:	P54444	Sequences: MAHLKFTLTKKLALLIMVAAIVSGVIFLTLQKITDDLIEGYLSSEEYYHEESARYIQKFSKYVSENELSTSDRKAFGEWVKKENYINLTIFKDQELQYDSIYSESDYGKEKLTQYAQNHSHPVKFSDGEGRVIIDGFYSSRYYDLAFALDLLGATLIFLIIVLFGIRQSLRYLKTIHQEIHILEGGELDYEMTIKGHDELAMIAKSIEDLRKAFLDKLKAIEELQAESRSLVTEMSHDMRTPLTSLIMNLEFAKKEGGEAGASKDRYVANAYGKALQLKSLSDNLFAYFLLNKEYEADLETVAVKEVIYDLISDQIAILHQEHFRVHISGELPETYINVNLEELGRVFDNVMSNLLKYADPEEKISITFVSDQEIFEIHVSNTIKLADITPESNGLGERSIARMMSRMQGQFHSIQKNSKYYIVLRFWNTKM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	432 (396)
Sequences:	46202 (39926)
Seq/√Len:	2006.4

ECOLI - BARA BAES GLRK YEDV TORS CPXA CUSS PHOQ QSEC CREC ENVZ RSTB NARX ATOS NARQ ZRAS RCSC RCSD ARCB DCUS EVGS BASS DPIB KDPD PHOR UHPB YPDA
BACSU - YRKQ YCLK YYCG CSSS YKOH YVRG RESE PHOR KINB YVCQ YCBM DCTS KIND LIAS YESM YBDK MALK CITS YXDK KINE BCES GLNK KINA COMP KINC LYTS
HALSA - Q9HQ15 Q9HQE9 Q9HQG5 Q9HQ16 Q9HRG1 O51970 Q9HRE4 Q9HR10

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
381_S	420_K	4.161	1.00
375_I	424_V	3.816	1.00
302_V	339_V	3.632	1.00
402_A	406_S	3.574	1.00
413_H	422_Y	3.478	1.00
379_H	420_K	3.302	1.00
250_L	271_A	3.254	1.00
327_H	366_S	2.954	1.00
379_H	422_Y	2.917	1.00
368_T	379_H	2.901	1.00
377_E	424_V	2.864	1.00
339_V	408_M	2.777	1.00
327_H	364_K	2.770	1.00
377_E	422_Y	2.763	1.00
301_T	338_N	2.755	1.00
254_K	272_Y	2.754	1.00
359_A	383_T	2.687	1.00
247_I	276_L	2.654	1.00
370_V	377_E	2.632	1.00
364_K	383_T	2.624	1.00
384_I	387_A	2.618	1.00
415_I	422_Y	2.614	1.00
254_K	269_A	2.604	1.00
415_I	420_K	2.577	1.00
366_S	381_S	2.567	1.00
414_S	421_Y	2.546	1.00
329_S	368_T	2.531	1.00
347_V	405_M	2.525	1.00
301_T	336_Y	2.502	1.00
416_Q	419_S	2.417	1.00
370_V	379_H	2.410	1.00
401_I	412_F	2.353	1.00
368_T	381_S	2.334	1.00
411_Q	424_V	2.310	1.00
325_R	364_K	2.258	1.00
405_M	410_G	2.227	1.00
310_D	345_G	2.222	1.00
247_I	275_A	2.218	1.00
303_A	306_E	2.169	1.00
300_E	341_L	2.155	1.00
329_S	366_S	2.148	1.00
247_I	279_K	2.065	1.00
315_Q	349_D	2.055	1.00
299_L	338_N	2.034	1.00
279_K	283_D	1.999	1.00
339_V	344_L	1.963	1.00
413_H	424_V	1.951	1.00
347_V	404_M	1.932	1.00
198_D	201_A	1.927	1.00
405_M	423_I	1.915	1.00
372_D	377_E	1.817	1.00
353_S	357_K	1.815	1.00
319_L	356_L	1.802	1.00
347_V	401_I	1.780	1.00
359_A	363_E	1.780	1.00
230_S	234_E	1.771	1.00
228_S	232_V	1.755	1.00
384_I	388_D	1.753	1.00
404_M	408_M	1.733	1.00
251_E	272_Y	1.711	1.00
406_S	411_Q	1.699	1.00
254_K	265_D	1.665	1.00
348_F	378_I	1.629	1.00
196_G	201_A	1.612	1.00
182_I	187_E	1.610	1.00
250_L	272_Y	1.609	1.00
253_A	268_V	1.601	1.00
305_K	309_Y	1.600	1.00
382_N	419_S	1.596	1.00
350_N	401_I	1.594	1.00
363_E	383_T	1.586	1.00
366_S	383_T	1.570	1.00
177_H	181_H	1.564	1.00
249_N	267_Y	1.563	1.00
340_N	343_E	1.561	1.00
222_E	226_A	1.555	1.00
272_Y	276_L	1.530	1.00
197_H	201_A	1.519	1.00
246_L	275_A	1.505	1.00
386_L	389_I	1.491	1.00
52_S	55_Y	1.488	1.00
310_D	341_L	1.477	1.00
226_A	230_S	1.452	1.00
314_D	345_G	1.452	1.00
382_N	418_N	1.448	1.00
343_E	346_R	1.437	1.00
359_A	365_I	1.436	1.00
177_H	202_M	1.431	1.00
246_L	271_A	1.430	1.00
91_F	95_E	1.430	1.00
305_K	369_F	1.428	1.00
247_I	272_Y	1.413	1.00
204_A	208_E	1.412	1.00
238_D	346_R	1.400	1.00
341_L	345_G	1.396	1.00
384_I	389_I	1.394	1.00
180_I	183_L	1.367	1.00
162_V	166_I	1.364	1.00
378_I	423_I	1.364	1.00
48_Y	52_S	1.364	1.00
375_I	411_Q	1.353	1.00
347_V	423_I	1.344	1.00
303_A	336_Y	1.341	1.00
297_A	340_N	1.339	1.00
405_M	412_F	1.339	1.00
309_Y	328_I	1.329	1.00
183_L	211_R	1.326	1.00
312_I	328_I	1.323	1.00
343_E	407_R	1.319	1.00
130_G	134_I	1.316	1.00
56_I	59_F	1.314	1.00
225_Q	228_S	1.313	1.00
256_E	264_K	1.312	1.00
343_E	404_M	1.310	1.00
245_S	274_K	1.304	1.00
303_A	334_E	1.300	1.00
280_S	342_E	1.296	1.00
34_T	37_L	1.296	1.00
385_K	388_D	1.285	1.00
316_I	320_H	1.280	1.00
403_R	406_S	1.279	1.00
253_A	264_K	1.275	1.00
223_E	227_E	1.272	1.00
414_S	419_S	1.270	1.00
203_I	207_I	1.269	1.00
182_I	190_Y	1.267	1.00
180_I	184_E	1.265	1.00
166_I	170_L	1.242	1.00
245_S	249_N	1.237	1.00
249_N	270_N	1.234	1.00
187_E	190_Y	1.233	1.00
250_L	275_A	1.216	1.00
350_N	353_S	1.214	1.00
174_K	177_H	1.209	1.00
410_G	425_L	1.208	1.00
305_K	334_E	1.200	1.00
204_A	207_I	1.187	1.00
131_R	135_D	1.184	1.00
269_A	273_G	1.179	1.00
299_L	408_M	1.174	1.00
191_E	212_K	1.172	1.00
318_I	321_Q	1.172	1.00
307_V	311_L	1.171	1.00
28_L	31_Q	1.166	1.00
250_L	254_K	1.164	1.00
311_L	349_D	1.161	1.00
344_L	408_M	1.152	1.00
240_R	283_D	1.147	1.00
355_L	365_I	1.145	1.00
231_L	235_M	1.142	1.00
308_I	369_F	1.134	1.00
330_G	369_F	1.128	1.00
49_H	53_A	1.127	1.00
110_E	119_H	1.127	1.00
265_D	269_A	1.122	1.00
210_L	214_F	1.122	1.00
208_E	211_R	1.107	1.00
145_L	149_L	1.103	1.00
38_I	41_Y	1.100	1.00
207_I	210_L	1.098	1.00
311_L	345_G	1.095	1.00
335_T	376_F	1.083	1.00
179_E	192_M	1.080	1.00
283_D	287_A	1.078	1.00
311_L	315_Q	1.074	1.00
245_S	248_M	1.067	1.00
38_I	42_L	1.060	1.00
176_I	180_I	1.057	1.00
180_I	207_I	1.049	1.00
177_H	206_S	1.040	1.00
55_Y	58_K	1.040	1.00
351_V	421_Y	1.038	1.00
304_V	378_I	1.034	1.00
250_L	268_V	1.029	1.00
258_G	264_K	1.028	1.00
302_V	307_V	1.027	1.00
60_S	64_S	1.022	1.00
266_R	270_N	1.016	1.00
248_M	252_F	1.015	1.00
181_H	202_M	1.011	1.00
372_D	375_I	1.011	1.00
257_G	264_K	1.011	1.00
305_K	330_G	1.010	1.00
349_D	353_S	1.008	1.00
193_T	208_E	1.004	1.00
194_I	205_K	1.003	1.00
191_E	208_E	1.001	1.00
167_R	171_R	1.000	1.00
181_H	185_G	0.999	1.00
29_T	32_K	0.997	1.00
274_K	277_Q	0.995	1.00
222_E	225_Q	0.992	1.00
177_H	180_I	0.990	1.00
180_I	206_S	0.990	1.00
318_I	353_S	0.984	1.00
345_G	349_D	0.983	1.00
312_I	316_I	0.980	1.00
125_F	128_G	0.978	1.00
141_R	145_L	0.978	1.00
324_F	359_A	0.973	1.00
247_I	251_E	0.971	1.00
306_E	310_D	0.966	1.00
389_I	392_E	0.966	1.00
90_I	96_L	0.964	1.00
284_N	343_E	0.963	1.00
307_V	339_V	0.957	1.00
315_Q	352_M	0.957	1.00
131_R	137_F	0.955	1.00
207_I	211_R	0.954	1.00
172_Y	176_I	0.952	1.00
36_D	40_G	0.948	1.00
51_E	54_R	0.947	1.00
11_K	198_D	0.945	1.00
169_S	172_Y	0.942	1.00
297_A	343_E	0.941	1.00
270_N	274_K	0.940	1.00
314_D	349_D	0.940	1.00
36_D	39_E	0.936	1.00
48_Y	51_E	0.934	1.00
130_G	133_I	0.932	1.00
348_F	352_M	0.932	1.00
51_E	55_Y	0.926	1.00
39_E	43_S	0.925	1.00
37_L	41_Y	0.920	1.00
37_L	40_G	0.917	1.00
241_T	245_S	0.915	1.00
126_S	129_E	0.914	1.00
412_F	421_Y	0.912	1.00
342_E	345_G	0.911	1.00
303_A	335_T	0.910	1.00
351_V	401_I	0.908	1.00
179_E	190_Y	0.908	1.00
166_I	169_S	0.905	1.00
348_F	380_V	0.904	1.00
239_M	278_L	0.899	1.00
33_I	38_I	0.898	1.00
191_E	211_R	0.898	1.00
59_F	63_V	0.895	1.00
273_G	310_D	0.890	1.00
299_L	409_Q	0.890	1.00
49_H	52_S	0.889	1.00
238_D	350_N	0.888	1.00
402_A	411_Q	0.884	1.00
53_A	57_Q	0.883	1.00
200_L	203_I	0.883	1.00
298_D	340_N	0.882	1.00
403_R	407_R	0.882	1.00
28_L	32_K	0.880	1.00
201_A	205_K	0.880	1.00
262_A	265_D	0.878	1.00
130_G	136_G	0.875	1.00
144_D	148_A	0.874	1.00
201_A	204_A	0.867	1.00
184_E	209_D	0.866	1.00
62_Y	66_N	0.866	1.00
181_H	206_S	0.864	1.00
266_R	269_A	0.864	1.00
352_M	367_I	0.862	1.00
375_I	426_R	0.861	1.00
259_E	264_K	0.860	1.00
145_L	148_A	0.860	1.00
159_L	163_L	0.860	1.00
405_M	425_L	0.855	1.00
269_A	272_Y	0.854	1.00
308_I	348_F	0.852	1.00
229_R	292_N	0.852	1.00
96_L	99_D	0.852	1.00
41_Y	44_S	0.852	1.00
351_V	412_F	0.852	1.00
206_S	209_D	0.846	1.00
196_G	204_A	0.845	1.00
227_E	230_S	0.843	1.00
202_M	205_K	0.842	1.00
276_L	279_K	0.841	1.00
388_D	391_P	0.841	1.00
277_Q	345_G	0.839	1.00
280_S	284_N	0.838	1.00
360_D	363_E	0.837	1.00
35_D	39_E	0.836	1.00
164_F	168_Q	0.836	1.00
168_Q	171_R	0.833	1.00
240_R	279_K	0.833	1.00
237_H	350_N	0.833	1.00
287_A	346_R	0.833	1.00
347_V	408_M	0.833	1.00
351_V	423_I	0.832	1.00
299_L	339_V	0.828	1.00
271_A	275_A	0.828	1.00
286_F	289_F	0.824	1.00
85_Y	88_L	0.823	1.00
410_G	423_I	0.821	1.00
130_G	135_D	0.817	1.00
275_A	279_K	0.816	1.00
86_I	99_D	0.815	1.00
178_Q	182_I	0.814	1.00
192_M	208_E	0.813	1.00
203_I	206_S	0.810	1.00
372_D	424_V	0.810	1.00
308_I	367_I	0.809	1.00
180_I	203_I	0.808	1.00
264_K	267_Y	0.805	1.00
401_I	405_M	0.805	1.00
9_T	167_R	0.804	1.00
311_L	352_M	0.800	1.00
396_L	400_S	0.799	1.00
325_R	328_I	0.796	1.00
288_Y	399_R	0.792	1.00
315_Q	353_S	0.790	1.00
73_R	77_G	0.788	1.00
223_E	226_A	0.785	1.00
122_P	131_R	0.783	1.00
317_A	320_H	0.783	1.00
160_I	164_F	0.781	1.00
37_L	42_L	0.780	1.00
224_L	228_S	0.780	1.00
235_M	285_L	0.780	1.00
40_G	43_S	0.779	1.00
379_H	415_I	0.779	1.00
284_N	346_R	0.779	1.00
346_R	404_M	0.778	1.00
19_A	23_S	0.777	1.00
351_V	405_M	0.777	1.00
47_Y	51_E	0.776	1.00
309_Y	313_S	0.774	1.00
287_A	343_E	0.772	1.00
190_Y	193_T	0.770	1.00
387_A	391_P	0.769	1.00
302_V	341_L	0.766	1.00
179_E	182_I	0.765	1.00
304_V	337_I	0.764	1.00
385_K	389_I	0.763	1.00
367_I	380_V	0.760	1.00
382_N	417_K	0.760	1.00
295_Y	343_E	0.756	1.00
50_E	53_A	0.755	1.00
256_E	259_E	0.755	1.00
312_I	326_V	0.748	1.00
252_F	256_E	0.743	1.00
54_R	58_K	0.743	1.00
55_Y	62_Y	0.743	1.00
52_S	56_I	0.741	1.00
224_L	227_E	0.740	1.00
40_G	44_S	0.740	1.00
57_Q	60_S	0.738	1.00
324_F	356_L	0.736	1.00
61_K	65_E	0.735	1.00
163_L	167_R	0.734	1.00
243_L	282_S	0.731	1.00
237_H	241_T	0.730	1.00
238_D	242_P	0.729	1.00
297_A	407_R	0.729	1.00
124_K	127_D	0.729	1.00
313_S	316_I	0.727	1.00
50_E	54_R	0.727	1.00
171_R	175_T	0.722	1.00
88_L	96_L	0.722	1.00
232_V	235_M	0.721	1.00
174_K	178_Q	0.721	1.00
122_P	126_S	0.716	1.00
400_S	404_M	0.715	1.00
270_N	273_G	0.714	1.00
181_H	184_E	0.713	1.00
39_E	42_L	0.713	1.00
91_F	97_Q	0.713	1.00
69_S	72_D	0.713	1.00
55_Y	60_S	0.712	1.00
249_N	274_K	0.708	1.00
254_K	268_V	0.707	1.00
200_L	204_A	0.703	1.00
62_Y	65_E	0.703	1.00
142_Y	145_L	0.701	1.00
249_N	271_A	0.700	1.00
323_H	361_P	0.697	1.00
357_K	391_P	0.697	1.00
311_L	314_D	0.694	1.00
324_F	328_I	0.693	1.00
304_V	376_F	0.693	1.00
357_K	393_S	0.689	1.00
131_R	134_I	0.689	1.00
47_Y	50_E	0.687	1.00
238_D	400_S	0.686	1.00
183_L	210_L	0.686	1.00
365_I	380_V	0.686	1.00
211_R	214_F	0.683	1.00
319_L	365_I	0.680	1.00
130_G	138_Y	0.679	1.00
238_D	281_L	0.677	1.00
35_D	38_I	0.675	1.00
317_A	321_Q	0.674	1.00
190_Y	194_I	0.674	1.00
173_L	176_I	0.672	1.00
142_Y	146_A	0.671	1.00
192_M	204_A	0.667	1.00
267_Y	271_A	0.666	1.00
306_E	341_L	0.665	1.00
401_I	404_M	0.663	1.00
86_I	89_T	0.663	1.00
310_D	314_D	0.662	1.00
184_E	213_A	0.660	1.00
377_E	413_H	0.658	1.00
176_I	204_A	0.658	1.00
203_I	208_E	0.656	1.00
125_F	129_E	0.656	1.00
226_A	229_R	0.653	1.00
61_K	64_S	0.652	1.00
245_S	270_N	0.651	1.00
319_L	323_H	0.651	1.00
268_V	272_Y	0.649	1.00
346_R	349_D	0.648	1.00
302_V	338_N	0.648	1.00
91_F	94_Q	0.647	1.00
225_Q	229_R	0.646	1.00
99_D	102_Y	0.645	1.00
335_T	371_S	0.644	1.00
122_P	129_E	0.643	1.00
320_H	323_H	0.643	1.00
369_F	376_F	0.643	1.00
329_S	370_V	0.642	1.00
355_L	380_V	0.641	1.00
176_I	179_E	0.640	1.00
182_I	185_G	0.640	1.00
203_I	210_L	0.638	1.00
74_K	77_G	0.637	1.00
344_L	425_L	0.636	1.00
307_V	344_L	0.636	1.00
272_Y	275_A	0.633	1.00
56_I	63_V	0.632	1.00
179_E	208_E	0.632	1.00
182_I	186_G	0.632	1.00
274_K	314_D	0.632	1.00
384_I	391_P	0.631	1.00
34_T	39_E	0.629	1.00
244_T	248_M	0.628	1.00
416_Q	420_K	0.628	1.00
352_M	365_I	0.627	1.00
315_Q	356_L	0.627	1.00
77_G	81_K	0.627	1.00
168_Q	172_Y	0.626	1.00
249_N	253_A	0.626	1.00
234_E	238_D	0.626	1.00
175_T	179_E	0.624	1.00
413_H	423_I	0.623	1.00
319_L	326_V	0.623	1.00
58_K	61_K	0.622	1.00
319_L	324_F	0.622	1.00
387_A	390_T	0.620	1.00
10_K	14_L	0.619	1.00
209_D	213_A	0.619	1.00
267_Y	270_N	0.619	1.00
124_K	129_E	0.618	1.00
309_Y	330_G	0.617	1.00
75_A	78_E	0.615	1.00
34_T	38_I	0.615	1.00
276_L	280_S	0.614	1.00
381_S	417_K	0.613	1.00
141_R	144_D	0.612	1.00
360_D	383_T	0.611	1.00
146_A	149_L	0.610	1.00
102_Y	105_S	0.606	1.00
249_N	275_A	0.605	1.00
253_A	267_Y	0.603	1.00
231_L	238_D	0.601	1.00
48_Y	56_I	0.599	1.00
309_Y	312_I	0.599	1.00
25_V	29_T	0.598	1.00
173_L	177_H	0.595	1.00
135_D	138_Y	0.595	1.00
210_L	213_A	0.595	1.00
204_A	211_R	0.594	1.00
312_I	367_I	0.594	1.00
279_K	282_S	0.593	1.00
405_M	411_Q	0.592	1.00
100_S	103_S	0.592	1.00
27_F	31_Q	0.591	1.00
251_E	254_K	0.591	1.00
57_Q	61_K	0.591	1.00
137_F	140_S	0.590	1.00
17_M	20_A	0.589	1.00
256_E	267_Y	0.589	1.00
59_F	62_Y	0.588	1.00
313_S	317_A	0.585	1.00
399_R	403_R	0.583	1.00
58_K	62_Y	0.580	1.00
197_H	204_A	0.579	1.00
343_E	408_M	0.579	1.00
233_T	236_S	0.577	1.00
60_S	63_V	0.575	1.00
134_I	137_F	0.575	1.00
148_A	152_L	0.575	1.00
52_S	59_F	0.570	1.00
152_L	156_L	0.570	1.00
158_F	162_V	0.569	1.00
252_F	267_Y	0.569	1.00
296_E	299_L	0.567	1.00
76_F	79_W	0.567	1.00
15_L	19_A	0.567	1.00
305_K	332_L	0.566	1.00
263_S	267_Y	0.564	1.00
284_N	342_E	0.564	1.00
288_Y	403_R	0.563	1.00
16_I	19_A	0.562	1.00
18_V	21_I	0.562	1.00
67_E	70_T	0.562	1.00
335_T	369_F	0.561	1.00
230_S	403_R	0.560	1.00
175_T	178_Q	0.560	1.00
278_L	282_S	0.559	1.00
381_S	416_Q	0.559	1.00
307_V	345_G	0.559	1.00
89_T	93_D	0.559	1.00
14_L	17_M	0.559	1.00
172_Y	175_T	0.557	1.00
172_Y	177_H	0.556	1.00
410_G	426_R	0.556	1.00
236_S	242_P	0.555	1.00
244_T	247_I	0.555	1.00
337_I	376_F	0.553	1.00
229_R	234_E	0.553	1.00
188_L	211_R	0.552	1.00
187_E	191_E	0.551	1.00
173_L	203_I	0.550	1.00
246_L	274_K	0.550	1.00
239_M	242_P	0.548	1.00
198_D	202_M	0.548	1.00
305_K	335_T	0.547	1.00
248_M	275_A	0.547	1.00
54_R	57_Q	0.547	1.00
199_E	203_I	0.542	1.00
189_D	211_R	0.542	1.00
136_G	139_S	0.541	1.00
120_S	123_V	0.541	1.00
149_L	153_G	0.540	1.00
322_E	356_L	0.540	1.00
32_K	144_D	0.540	1.00
70_T	73_R	0.539	1.00
343_E	347_V	0.537	1.00
286_F	290_L	0.537	1.00
318_I	322_E	0.537	1.00
200_L	207_I	0.537	1.00
186_G	190_Y	0.536	1.00
236_S	286_F	0.536	1.00
55_Y	63_V	0.536	1.00
366_S	369_F	0.536	1.00
386_L	390_T	0.535	1.00
184_E	188_L	0.534	1.00
170_L	174_K	0.533	1.00
246_L	250_L	0.532	1.00
171_R	174_K	0.532	1.00
9_T	13_A	0.532	1.00
322_E	359_A	0.530	1.00
146_A	150_D	0.529	1.00
232_V	236_S	0.529	1.00
319_L	322_E	0.528	1.00
21_I	25_V	0.528	1.00
229_R	233_T	0.528	1.00
55_Y	59_F	0.526	1.00
194_I	197_H	0.525	1.00
147_F	150_D	0.524	1.00
369_F	378_I	0.523	1.00
175_T	193_T	0.521	1.00
56_I	60_S	0.521	1.00
178_Q	181_H	0.521	1.00
18_V	25_V	0.520	1.00
63_V	66_N	0.520	1.00
252_F	257_G	0.520	1.00
202_M	206_S	0.519	1.00
99_D	103_S	0.519	1.00
256_E	263_S	0.518	1.00
72_D	75_A	0.517	1.00
264_K	268_V	0.517	1.00
243_L	278_L	0.516	1.00
322_E	361_P	0.516	1.00
238_D	274_K	0.516	1.00
337_I	425_L	0.515	1.00
398_E	421_Y	0.512	1.00
101_I	104_E	0.511	1.00
305_K	333_P	0.511	1.00
235_M	239_M	0.510	1.00
194_I	204_A	0.509	1.00
180_I	210_L	0.508	1.00
122_P	125_F	0.507	1.00
352_M	356_L	0.506	1.00
308_I	311_L	0.505	1.00
195_K	201_A	0.504	1.00
242_P	278_L	0.503	1.00
236_S	241_T	0.503	1.00
198_D	204_A	0.502	1.00
257_G	265_D	0.502	1.00
130_G	137_F	0.502	1.00
133_I	137_F	0.501	1.00
310_D	313_S	0.501	1.00
9_T	174_K	0.500	1.00
371_S	376_F	0.500	1.00
67_E	71_S	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4i5sA	2	0.6019	100	0.408	Contact Map
4bixA	2	0.4931	100	0.445	Contact Map
4ctiA	2	0.5255	100	0.491	Contact Map
3a0rA	2	0.7292	100	0.525	Contact Map
4q20A	2	0.4954	100	0.528	Contact Map
2q8gA	2	0.6644	100	0.536	Contact Map
4mpcA	2	0.6736	100	0.54	Contact Map
4gczA	2	0.7894	100	0.542	Contact Map
3jz3A	2	0.3657	100	0.548	Contact Map
4r39A	1	0.4653	100	0.549	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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