YRKA - BACSU - GREMLIN Contacts

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YRKA - UPF0053 protein YrkA

UniProt:	P54428	Sequences: MTTINLIIFTLLIVLTAFFVATEFAIVKIRSSKIDQLILEGKKGAISAKKVITHLDEYLSACQLGITVTALGIGWVGESTFEVILHPLFAHFHVSETVSHVLILVIAFVMATFLHVVVGELAPKTLAIQKAETITLLTAKPIIWFYRILFPFIWFLNGSARFIVGLFGLKPASEHELAHSEEELRILLSESYKSGEINQNELKYVNNIFEFDERIAKEIMIPRREIVAISSEDSYETIVKIIKTESYTRYPVLNGDKDSIIGFINAKEFLSAYIDTDQKIKEDFKLENHINPVIHVIESVPIHDVLVKMQKERTHIAILVDEYGGTSGLVTAEDILEEIVGEIRDEFDKDEVPNIRKVNDNHYILDSKVLIEDVNDLLGTTLASDEVDTIGGWFMTQQIDAAVGSVIEADGYIFKVHETVGRHINYLEIVRKKE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	434 (409)
Sequences:	8280 (5390)
Seq/√Len:	266.5

ECOLI - YTFL YFJD YEGH YOAE CORC
BACSU - YRKA YUGS YHDP YHDT YQHB
HALSA - Q9HHN9 Q9HN02 Q9HRX1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
226_I	329_L	4.378	1.00
400_D	405_S	3.912	1.00
365_L	429_I	3.546	1.00
408_E	413_I	3.509	1.00
406_V	413_I	3.444	1.00
406_V	415_K	3.326	1.00
254_N	259_S	3.202	1.00
296_V	305_V	3.144	1.00
234_S	237_T	3.136	1.00
394_F	427_L	3.086	1.00
233_D	237_T	2.983	1.00
268_E	291_N	2.920	1.00
285_K	288_N	2.909	1.00
364_I	417_H	2.893	1.00
228_A	253_L	2.886	1.00
359_N	362_H	2.860	1.00
254_N	287_E	2.786	1.00
130_K	133_T	2.674	1.00
143_I	147_R	2.667	1.00
252_V	290_I	2.648	1.00
231_S	254_N	2.617	1.00
154_W	158_G	2.587	1.00
364_I	426_Y	2.513	1.00
216_A	305_V	2.475	1.00
318_I	329_L	2.455	1.00
34_I	48_A	2.370	1.00
113_F	159_S	2.359	1.00
226_I	326_T	2.341	1.00
300_V	308_K	2.289	1.00
374_V	378_L	2.253	1.00
162_F	166_L	2.224	1.00
228_A	257_K	2.216	1.00
231_S	287_E	2.163	1.00
47_S	143_I	2.153	1.00
393_W	409_A	2.134	1.00
358_V	362_H	2.104	1.00
231_S	261_I	2.089	1.00
305_V	330_V	2.075	1.00
229_I	238_I	2.072	1.00
417_H	428_E	2.067	1.00
263_F	293_V	2.057	1.00
18_F	141_P	2.056	1.00
390_I	427_L	2.053	1.00
57_E	150_F	2.050	1.00
47_S	140_K	2.037	1.00
318_I	326_T	2.028	1.00
362_H	428_E	2.015	1.00
418_E	426_Y	1.983	1.00
219_I	330_V	1.970	1.00
374_V	429_I	1.920	1.00
37_L	136_L	1.904	1.00
229_I	252_V	1.899	1.00
33_K	132_E	1.880	1.00
219_I	302_I	1.859	1.00
240_K	244_T	1.855	1.00
38_I	49_K	1.854	1.00
137_L	141_P	1.805	1.00
369_V	374_V	1.801	1.00
333_E	337_E	1.786	1.00
42_K	136_L	1.776	1.00
355_I	369_V	1.773	1.00
420_V	425_N	1.769	1.00
16_T	70_A	1.767	1.00
253_L	260_I	1.753	1.00
188_L	205_V	1.745	1.00
233_D	238_I	1.730	1.00
418_E	425_N	1.694	1.00
248_T	265_N	1.690	1.00
357_K	363_Y	1.689	1.00
214_R	218_E	1.685	1.00
50_K	143_I	1.681	1.00
158_G	162_F	1.676	1.00
369_V	390_I	1.664	1.00
316_I	329_L	1.639	1.00
208_I	339_I	1.603	1.00
22_T	138_T	1.600	1.00
415_K	428_E	1.582	1.00
374_V	390_I	1.579	1.00
204_Y	208_I	1.565	1.00
230_S	233_D	1.556	1.00
227_V	241_I	1.546	1.00
298_E	327_S	1.540	1.00
254_N	261_I	1.537	1.00
133_T	137_L	1.535	1.00
232_E	254_N	1.527	1.00
394_F	414_F	1.523	1.00
375_N	380_T	1.518	1.00
365_L	390_I	1.513	1.00
47_S	139_A	1.480	1.00
302_I	335_I	1.479	1.00
364_I	428_E	1.478	1.00
256_D	259_S	1.473	1.00
395_M	424_I	1.465	1.00
284_F	288_N	1.448	1.00
357_K	360_D	1.446	1.00
300_V	305_V	1.439	1.00
358_V	364_I	1.438	1.00
48_A	139_A	1.438	1.00
394_F	416_V	1.436	1.00
16_T	66_I	1.432	1.00
307_V	310_Q	1.429	1.00
150_F	154_W	1.425	1.00
365_L	374_V	1.424	1.00
35_D	39_L	1.424	1.00
147_R	150_F	1.414	1.00
71_L	74_G	1.401	1.00
263_F	316_I	1.389	1.00
227_V	247_Y	1.387	1.00
224_R	325_G	1.386	1.00
82_E	86_H	1.382	1.00
394_F	407_I	1.371	1.00
7_I	11_L	1.365	1.00
49_K	53_T	1.361	1.00
345_D	348_D	1.357	1.00
245_E	250_Y	1.357	1.00
358_V	428_E	1.355	1.00
6_L	10_T	1.352	1.00
414_F	427_L	1.352	1.00
37_L	42_K	1.351	1.00
204_Y	339_I	1.350	1.00
227_V	250_Y	1.349	1.00
249_R	315_H	1.347	1.00
409_A	414_F	1.345	1.00
358_V	361_N	1.333	1.00
21_A	134_I	1.330	1.00
105_V	109_V	1.327	1.00
101_V	105_V	1.316	1.00
308_K	312_E	1.312	1.00
38_I	46_I	1.309	1.00
387_V	396_T	1.305	1.00
61_A	145_F	1.303	1.00
237_T	240_K	1.299	1.00
35_D	49_K	1.294	1.00
41_G	45_A	1.289	1.00
227_V	245_E	1.284	1.00
48_A	135_T	1.283	1.00
138_T	141_P	1.274	1.00
397_Q	409_A	1.273	1.00
223_R	258_D	1.267	1.00
158_G	161_R	1.264	1.00
316_I	331_T	1.259	1.00
394_F	398_Q	1.257	1.00
141_P	144_W	1.253	1.00
417_H	426_Y	1.253	1.00
46_I	50_K	1.252	1.00
258_D	325_G	1.247	1.00
140_K	144_W	1.232	1.00
258_D	326_T	1.219	1.00
336_L	340_V	1.218	1.00
63_Q	66_I	1.208	1.00
44_G	136_L	1.207	1.00
293_V	318_I	1.199	1.00
412_Y	429_I	1.194	1.00
233_D	241_I	1.187	1.00
42_K	45_A	1.184	1.00
355_I	377_L	1.181	1.00
375_N	382_L	1.180	1.00
86_H	90_A	1.172	1.00
15_L	69_T	1.172	1.00
223_R	325_G	1.170	1.00
11_L	15_L	1.168	1.00
371_I	375_N	1.164	1.00
61_A	153_I	1.162	1.00
19_F	145_F	1.144	1.00
43_K	46_I	1.141	1.00
216_A	319_L	1.137	1.00
24_F	27_V	1.126	1.00
260_I	318_I	1.122	1.00
297_I	300_V	1.121	1.00
122_A	163_I	1.119	1.00
398_Q	401_A	1.116	1.00
216_A	296_V	1.115	1.00
126_L	169_L	1.108	1.00
261_I	290_I	1.104	1.00
236_E	240_K	1.102	1.00
217_K	298_E	1.100	1.00
407_I	414_F	1.099	1.00
44_G	140_K	1.098	1.00
19_F	65_G	1.069	1.00
77_G	111_A	1.068	1.00
333_E	343_I	1.066	1.00
343_I	348_D	1.061	1.00
391_G	395_M	1.060	1.00
228_A	326_T	1.054	1.00
162_F	165_G	1.050	1.00
354_N	366_D	1.047	1.00
356_R	364_I	1.046	1.00
264_I	289_H	1.044	1.00
378_L	412_Y	1.043	1.00
408_E	411_G	1.034	1.00
8_I	76_V	1.033	1.00
144_W	147_R	1.032	1.00
398_Q	407_I	1.028	1.00
249_R	333_E	1.027	1.00
230_S	255_G	1.022	1.00
296_V	319_L	1.011	1.00
18_F	138_T	1.010	1.00
9_F	111_A	1.009	1.00
70_A	115_H	1.007	1.00
296_V	317_A	1.003	1.00
192_Y	202_L	1.002	1.00
16_T	20_V	0.998	1.00
66_I	70_A	0.996	1.00
294_I	308_K	0.994	1.00
225_E	423_H	0.994	1.00
13_I	114_L	0.993	1.00
219_I	335_I	0.992	1.00
255_G	259_S	0.990	1.00
179_H	187_L	0.989	1.00
61_A	146_Y	0.979	1.00
34_I	49_K	0.979	1.00
23_E	124_K	0.976	1.00
81_F	84_I	0.970	1.00
21_A	127_A	0.967	1.00
309_M	317_A	0.966	1.00
119_G	124_K	0.958	1.00
393_W	414_F	0.956	1.00
355_I	363_Y	0.951	1.00
184_L	191_S	0.950	1.00
403_V	418_E	0.948	1.00
355_I	365_L	0.944	1.00
191_S	195_G	0.943	1.00
29_I	131_A	0.933	1.00
272_A	289_H	0.932	1.00
165_G	170_K	0.929	1.00
370_L	373_D	0.926	1.00
137_L	140_K	0.925	1.00
51_V	58_Y	0.923	1.00
50_K	54_H	0.920	1.00
36_Q	40_E	0.919	1.00
231_S	290_I	0.918	1.00
54_H	57_E	0.914	1.00
229_I	286_L	0.912	1.00
45_A	136_L	0.911	1.00
300_V	304_D	0.909	1.00
243_K	275_D	0.908	1.00
232_E	287_E	0.908	1.00
366_D	426_Y	0.908	1.00
284_F	289_H	0.905	1.00
397_Q	407_I	0.903	1.00
240_K	243_K	0.903	1.00
230_S	253_L	0.902	1.00
63_Q	67_T	0.902	1.00
20_V	24_F	0.902	1.00
375_N	381_T	0.900	1.00
242_I	250_Y	0.893	1.00
85_L	88_L	0.892	1.00
71_L	75_W	0.890	1.00
344_R	351_E	0.886	1.00
367_S	390_I	0.885	1.00
47_S	50_K	0.883	1.00
151_P	155_F	0.882	1.00
239_V	243_K	0.882	1.00
51_V	139_A	0.881	1.00
297_I	322_E	0.880	1.00
44_G	48_A	0.879	1.00
120_E	124_K	0.879	1.00
74_G	77_G	0.878	1.00
294_I	317_A	0.870	1.00
9_F	73_I	0.869	1.00
146_Y	150_F	0.867	1.00
414_F	429_I	0.866	1.00
226_I	257_K	0.863	1.00
109_V	113_F	0.861	1.00
88_L	91_H	0.861	1.00
29_I	34_I	0.856	1.00
251_P	260_I	0.853	1.00
393_W	397_Q	0.850	1.00
333_E	346_E	0.849	1.00
38_I	42_K	0.847	1.00
22_T	142_I	0.846	1.00
211_F	335_I	0.846	1.00
164_V	169_L	0.844	1.00
391_G	423_H	0.844	1.00
17_A	21_A	0.843	1.00
155_F	158_G	0.838	0.99
337_E	342_E	0.837	0.99
71_L	78_E	0.833	0.99
268_E	347_F	0.832	0.99
34_I	52_I	0.830	0.99
211_F	306_L	0.829	0.99
235_Y	284_F	0.826	0.99
161_R	165_G	0.824	0.99
33_K	37_L	0.820	0.99
315_H	336_L	0.820	0.99
211_F	303_H	0.819	0.99
321_D	324_G	0.819	0.99
337_E	345_D	0.817	0.99
333_E	338_E	0.816	0.99
248_T	267_K	0.815	0.99
305_V	335_I	0.813	0.99
24_F	127_A	0.813	0.99
333_E	348_D	0.812	0.99
8_I	11_L	0.812	0.99
333_E	345_D	0.811	0.99
71_L	112_T	0.810	0.99
75_W	108_F	0.809	0.99
235_Y	238_I	0.804	0.99
272_A	277_D	0.803	0.99
382_L	393_W	0.800	0.99
367_S	391_G	0.797	0.99
12_L	72_G	0.796	0.99
321_D	327_S	0.796	0.99
70_A	74_G	0.794	0.99
84_I	87_P	0.794	0.99
253_L	256_D	0.794	0.99
424_I	427_L	0.790	0.99
223_R	321_D	0.789	0.99
321_D	325_G	0.786	0.99
170_K	174_E	0.785	0.99
16_T	115_H	0.780	0.99
56_D	161_R	0.778	0.99
294_I	312_E	0.778	0.99
103_I	107_A	0.777	0.99
251_P	318_I	0.777	0.99
241_I	244_T	0.776	0.99
229_I	250_Y	0.772	0.99
295_H	320_V	0.765	0.99
333_E	342_E	0.763	0.99
216_A	330_V	0.763	0.99
229_I	241_I	0.760	0.99
55_L	58_Y	0.756	0.99
274_I	277_D	0.753	0.99
64_L	152_F	0.751	0.99
73_I	111_A	0.751	0.99
44_G	139_A	0.751	0.99
14_V	17_A	0.749	0.99
287_E	290_I	0.743	0.99
225_E	368_K	0.743	0.99
371_I	387_V	0.740	0.99
260_I	326_T	0.739	0.99
320_V	326_T	0.738	0.99
140_K	143_I	0.737	0.99
383_A	387_V	0.737	0.99
185_R	210_E	0.734	0.99
231_S	238_I	0.732	0.99
202_L	206_N	0.730	0.99
243_K	271_S	0.729	0.99
265_N	268_E	0.728	0.99
18_F	65_G	0.726	0.99
242_I	266_A	0.725	0.99
66_I	115_H	0.725	0.99
366_D	369_V	0.723	0.98
67_T	112_T	0.722	0.98
293_V	316_I	0.722	0.98
31_S	53_T	0.721	0.98
85_L	89_F	0.720	0.98
181_E	213_E	0.720	0.98
425_N	428_E	0.718	0.98
387_V	393_W	0.717	0.98
249_R	265_N	0.717	0.98
242_I	269_F	0.716	0.98
403_V	419_T	0.710	0.98
215_I	218_E	0.709	0.98
214_R	338_E	0.708	0.98
51_V	55_L	0.708	0.98
72_G	76_V	0.708	0.98
102_L	106_I	0.705	0.98
398_Q	405_S	0.703	0.98
356_R	426_Y	0.702	0.98
207_N	339_I	0.702	0.98
21_A	25_A	0.701	0.98
82_E	100_H	0.699	0.98
338_E	342_E	0.699	0.98
358_V	418_E	0.698	0.98
380_T	412_Y	0.698	0.98
308_K	311_K	0.697	0.98
397_Q	410_D	0.696	0.98
135_T	139_A	0.695	0.98
37_L	45_A	0.694	0.98
69_T	73_I	0.694	0.98
367_S	424_I	0.693	0.98
181_E	185_R	0.692	0.98
374_V	377_L	0.692	0.98
322_E	392_G	0.690	0.98
332_A	343_I	0.685	0.98
75_W	116_V	0.683	0.98
391_G	424_I	0.682	0.98
251_P	263_F	0.677	0.98
381_T	410_D	0.674	0.98
217_K	327_S	0.674	0.98
66_I	120_E	0.673	0.98
62_C	66_I	0.672	0.98
33_K	36_Q	0.670	0.98
261_I	287_E	0.669	0.97
216_A	300_V	0.667	0.97
148_I	151_P	0.666	0.97
184_L	197_I	0.666	0.97
357_K	361_N	0.665	0.97
386_E	396_T	0.664	0.97
37_L	40_E	0.662	0.97
315_H	333_E	0.662	0.97
189_S	206_N	0.661	0.97
221_I	344_R	0.661	0.97
167_F	170_K	0.660	0.97
29_I	132_E	0.660	0.97
20_V	120_E	0.659	0.97
134_I	138_T	0.656	0.97
223_R	323_Y	0.656	0.97
73_I	115_H	0.654	0.97
238_I	286_L	0.654	0.97
8_I	12_L	0.654	0.97
352_V	356_R	0.654	0.97
229_I	233_D	0.653	0.97
15_L	19_F	0.652	0.97
227_V	244_T	0.652	0.97
181_E	212_D	0.652	0.97
265_N	291_N	0.651	0.97
337_E	348_D	0.650	0.97
272_A	275_D	0.650	0.97
272_A	276_T	0.649	0.97
204_Y	211_F	0.646	0.97
229_I	242_I	0.646	0.97
121_L	156_L	0.645	0.97
66_I	69_T	0.644	0.97
20_V	115_H	0.640	0.97
10_T	14_V	0.639	0.97
371_I	382_L	0.639	0.97
23_E	120_E	0.638	0.97
86_H	103_I	0.638	0.97
355_I	374_V	0.638	0.97
249_R	346_E	0.638	0.97
181_E	209_F	0.637	0.97
402_A	405_S	0.637	0.97
354_N	369_V	0.636	0.97
66_I	121_L	0.636	0.97
236_E	283_D	0.635	0.97
236_E	282_E	0.634	0.97
71_L	108_F	0.634	0.97
70_A	76_V	0.629	0.96
249_R	316_I	0.627	0.96
282_E	285_K	0.626	0.96
306_L	335_I	0.624	0.96
13_I	119_G	0.624	0.96
185_R	206_N	0.624	0.96
377_L	380_T	0.623	0.96
337_E	341_G	0.623	0.96
13_I	16_T	0.623	0.96
237_T	241_I	0.622	0.96
375_N	385_D	0.621	0.96
62_C	142_I	0.621	0.96
59_L	63_Q	0.621	0.96
82_E	103_I	0.620	0.96
223_R	324_G	0.620	0.96
157_N	161_R	0.619	0.96
25_A	135_T	0.615	0.96
64_L	71_L	0.615	0.96
306_L	340_V	0.613	0.96
28_K	128_I	0.613	0.96
16_T	63_Q	0.612	0.96
56_D	125_T	0.611	0.96
152_F	156_L	0.610	0.96
44_G	137_L	0.609	0.96
85_L	103_I	0.609	0.96
118_V	163_I	0.608	0.96
238_I	242_I	0.607	0.96
86_H	100_H	0.607	0.96
145_F	149_L	0.607	0.96
16_T	67_T	0.606	0.96
357_K	362_H	0.606	0.96
212_D	303_H	0.606	0.96
51_V	146_Y	0.605	0.95
78_E	83_V	0.601	0.95
164_V	168_G	0.597	0.95
131_A	134_I	0.597	0.95
294_I	314_T	0.596	0.95
126_L	134_I	0.595	0.95
419_T	422_R	0.595	0.95
35_D	38_I	0.594	0.95
54_H	146_Y	0.593	0.95
180_S	184_L	0.591	0.95
76_V	80_T	0.591	0.95
76_V	79_S	0.590	0.95
33_K	45_A	0.590	0.95
5_N	9_F	0.589	0.95
305_V	309_M	0.589	0.95
62_C	108_F	0.589	0.95
16_T	69_T	0.588	0.95
82_E	85_L	0.588	0.95
307_V	311_K	0.587	0.95
61_A	64_L	0.587	0.95
74_G	79_S	0.584	0.95
59_L	119_G	0.583	0.94
63_Q	70_A	0.582	0.94
295_H	318_I	0.582	0.94
210_E	213_E	0.582	0.94
211_F	301_P	0.580	0.94
29_I	48_A	0.579	0.94
355_I	359_N	0.577	0.94
365_L	378_L	0.577	0.94
133_T	136_L	0.576	0.94
413_I	417_H	0.574	0.94
13_I	73_I	0.574	0.94
27_V	128_I	0.574	0.94
394_F	401_A	0.572	0.94
205_V	209_F	0.572	0.94
34_I	45_A	0.571	0.94
67_T	115_H	0.570	0.94
260_I	295_H	0.569	0.94
69_T	112_T	0.569	0.94
29_I	136_L	0.568	0.94
64_L	67_T	0.567	0.94
240_K	275_D	0.567	0.94
48_A	52_I	0.566	0.94
230_S	259_S	0.565	0.94
20_V	66_I	0.565	0.94
211_F	339_I	0.565	0.94
58_Y	64_L	0.564	0.93
50_K	147_R	0.564	0.93
401_A	405_S	0.564	0.93
306_L	309_M	0.563	0.93
288_N	292_P	0.563	0.93
263_F	290_I	0.562	0.93
79_S	83_V	0.562	0.93
253_L	257_K	0.562	0.93
337_E	343_I	0.561	0.93
20_V	70_A	0.561	0.93
67_T	108_F	0.560	0.93
203_K	207_N	0.558	0.93
185_R	205_V	0.558	0.93
65_G	77_G	0.558	0.93
42_K	46_I	0.558	0.93
25_A	134_I	0.557	0.93
20_V	63_Q	0.557	0.93
375_N	384_S	0.556	0.93
89_F	103_I	0.555	0.93
276_T	282_E	0.554	0.93
257_K	326_T	0.553	0.93
194_S	197_I	0.553	0.93
50_K	53_T	0.552	0.93
223_R	322_E	0.552	0.93
70_A	73_I	0.552	0.93
315_H	332_A	0.551	0.93
398_Q	406_V	0.550	0.93
383_A	397_Q	0.549	0.93
253_L	259_S	0.548	0.92
371_I	374_V	0.548	0.92
46_I	49_K	0.546	0.92
79_S	82_E	0.544	0.92
265_N	315_H	0.543	0.92
37_L	41_G	0.541	0.92
44_G	47_S	0.540	0.92
343_I	346_E	0.539	0.92
217_K	388_D	0.539	0.92
78_E	82_E	0.538	0.92
12_L	17_A	0.535	0.92
163_I	167_F	0.535	0.92
393_W	407_I	0.534	0.92
216_A	301_P	0.532	0.91
104_L	108_F	0.532	0.91
395_M	405_S	0.532	0.91
180_S	183_E	0.531	0.91
70_A	75_W	0.531	0.91
89_F	102_L	0.530	0.91
80_T	107_A	0.530	0.91
70_A	121_L	0.530	0.91
333_E	340_V	0.529	0.91
419_T	424_I	0.528	0.91
59_L	62_C	0.528	0.91
60_S	69_T	0.528	0.91
304_D	307_V	0.527	0.91
63_Q	115_H	0.527	0.91
363_Y	378_L	0.527	0.91
30_R	183_E	0.527	0.91
306_L	332_A	0.527	0.91
371_I	390_I	0.526	0.91
191_S	196_E	0.525	0.91
60_S	67_T	0.525	0.91
344_R	350_D	0.525	0.91
315_H	343_I	0.525	0.91
393_W	410_D	0.525	0.91
125_T	128_I	0.523	0.91
363_Y	377_L	0.523	0.91
129_Q	169_L	0.522	0.91
248_T	345_D	0.522	0.91
365_L	377_L	0.522	0.91
332_A	340_V	0.521	0.91
262_G	290_I	0.521	0.91
238_I	285_K	0.520	0.90
21_A	138_T	0.519	0.90
116_V	120_E	0.519	0.90
378_L	429_I	0.519	0.90
78_E	100_H	0.518	0.90
322_E	325_G	0.517	0.90
66_I	119_G	0.517	0.90
298_E	324_G	0.517	0.90
67_T	120_E	0.515	0.90
32_S	186_I	0.514	0.90
372_E	376_D	0.514	0.90
57_E	146_Y	0.513	0.90
218_E	395_M	0.513	0.90
249_R	263_F	0.512	0.90
83_V	87_P	0.512	0.90
87_P	103_I	0.511	0.90
241_I	245_E	0.511	0.90
65_G	74_G	0.511	0.90
75_W	104_L	0.509	0.89
297_I	320_V	0.509	0.89
301_P	304_D	0.509	0.89
17_A	119_G	0.508	0.89
26_I	135_T	0.505	0.89
373_D	377_L	0.505	0.89
144_W	148_I	0.504	0.89
219_I	338_E	0.504	0.89
252_V	262_G	0.504	0.89
223_R	327_S	0.504	0.89
218_E	388_D	0.503	0.89
220_M	328_G	0.503	0.89
272_A	284_F	0.503	0.89
48_A	51_V	0.502	0.89
290_I	293_V	0.502	0.89
242_I	270_L	0.501	0.89
223_R	226_I	0.500	0.89
71_L	107_A	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4hg0A	2	0.5323	100	0.5	Contact Map
3lhhA	1	0.288	100	0.762	Contact Map
3ocoA	2	0.3111	99.9	0.778	Contact Map
3oi8A	2	0.3594	99.9	0.779	Contact Map
3ocmA	5	0.3433	99.9	0.786	Contact Map
2v8qE	1	0.5138	99.9	0.788	Contact Map
3kxrA	3	0.371	99.9	0.788	Contact Map
3lv9A	2	0.2995	99.9	0.794	Contact Map
4iysA	2	0.3272	99.9	0.801	Contact Map
3t4nC	1	0.5276	99.9	0.807	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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