GREMLIN Database
YBXG - Uncharacterized transporter YbxG
UniProt: P54425 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 462 (420)
Sequences: 24594 (15946)
Seq/√Len: 778.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
134_G338_L4.3651.00
320_F332_Y4.2591.00
380_G384_A3.3371.00
51_G243_L3.2921.00
372_F407_I3.2331.00
323_K332_Y3.1251.00
229_N233_N3.0741.00
11_G225_K2.8331.00
224_A230_T2.7921.00
75_A314_N2.7841.00
166_G252_V2.6711.00
91_A311_L2.6691.00
226_D229_N2.6521.00
312_G322_K2.6321.00
16_Q237_S2.5531.00
127_I342_A2.5321.00
325_S331_L2.5041.00
222_G313_V2.4711.00
320_F323_K2.4621.00
63_E382_R2.3701.00
12_A237_S2.3571.00
164_I168_G2.3561.00
223_E306_R2.2991.00
375_L406_T2.2951.00
280_A284_I2.2881.00
79_H87_G2.2431.00
309_Y313_V2.2271.00
335_I339_I2.2081.00
12_A230_T2.1881.00
135_A139_I2.1721.00
134_G334_T2.1301.00
131_V342_A2.1251.00
142_K146_E2.1011.00
15_I224_A2.0741.00
12_A16_Q2.0651.00
404_Y408_A2.0291.00
138_L331_L2.0271.00
439_I443_V2.0261.00
271_S274_S1.9981.00
233_N237_S1.9971.00
16_Q241_R1.9771.00
82_I380_G1.9691.00
126_G345_V1.9661.00
60_A375_L1.9551.00
153_M157_V1.9511.00
95_W337_V1.9341.00
52_I56_F1.9251.00
79_H84_P1.9211.00
315_G319_K1.9161.00
127_I345_V1.8961.00
11_G14_H1.8941.00
258_P261_E1.8701.00
321_F336_A1.8691.00
35_T43_V1.8571.00
325_S329_V1.8311.00
433_F437_V1.8301.00
261_E275_K1.8241.00
137_N298_N1.7881.00
431_V435_A1.7871.00
408_A412_M1.7841.00
82_I376_I1.7801.00
226_D230_T1.7551.00
401_F405_L1.7501.00
271_S275_K1.7491.00
376_I407_I1.7491.00
236_Q240_W1.7431.00
106_I297_C1.7201.00
102_G341_L1.7191.00
14_H149_F1.7121.00
78_G90_T1.7081.00
46_A203_A1.6921.00
90_T373_I1.6881.00
131_V338_L1.6871.00
130_M341_L1.6791.00
42_S200_F1.6621.00
19_A238_I1.6531.00
432_I436_L1.6501.00
157_V161_L1.6131.00
327_N331_L1.6121.00
83_H86_A1.6021.00
10_L14_H1.5961.00
138_L335_I1.5941.00
121_P124_I1.5901.00
53_F409_F1.5641.00
92_W437_V1.5561.00
113_T125_P1.5531.00
56_F405_L1.5261.00
240_W244_I1.5241.00
309_Y324_I1.5211.00
220_T302_F1.5171.00
226_D233_N1.5111.00
380_G383_K1.5101.00
167_I252_V1.5091.00
308_L333_G1.4981.00
50_C207_V1.4951.00
7_K328_G1.4851.00
332_Y336_A1.4691.00
58_M239_I1.4631.00
274_S282_A1.4621.00
139_I327_N1.4491.00
265_L271_S1.4311.00
120_L124_I1.4311.00
158_T288_V1.4271.00
106_I130_M1.4261.00
265_L268_P1.4211.00
78_G373_I1.4201.00
52_I405_L1.4171.00
319_K323_K1.4171.00
304_A337_V1.4161.00
130_M338_L1.4101.00
71_T222_G1.4101.00
156_I160_I1.3981.00
109_V290_I1.3901.00
127_I131_V1.3891.00
376_I380_G1.3881.00
134_G335_I1.3801.00
319_K322_K1.3721.00
227_P232_R1.3661.00
305_G334_T1.3571.00
274_S279_T1.3511.00
244_I248_G1.3461.00
10_L15_I1.3401.00
60_A403_N1.3371.00
30_M108_A1.3351.00
436_L439_I1.3321.00
82_I86_A1.3311.00
443_V446_I1.3291.00
283_G287_F1.3271.00
42_S193_F1.3201.00
14_H145_G1.3201.00
67_V392_H1.3161.00
58_M235_I1.3131.00
323_K331_L1.3111.00
109_V129_A1.3101.00
230_T233_N1.3071.00
68_E80_Q1.3051.00
13_R17_M1.2921.00
163_I248_G1.2901.00
81_Y377_S1.2831.00
12_A233_N1.2661.00
44_L251_F1.2631.00
435_A439_I1.2581.00
398_F402_T1.2461.00
57_I375_L1.2381.00
59_R236_Q1.2371.00
10_L145_G1.2361.00
308_L317_A1.2351.00
105_E296_G1.2351.00
76_T80_Q1.2311.00
23_T242_I1.2311.00
372_F411_L1.2281.00
430_G434_L1.2261.00
379_I404_Y1.2211.00
133_L297_C1.2171.00
95_W308_L1.2151.00
85_M444_F1.2101.00
179_D184_S1.2071.00
166_G256_V1.1981.00
162_M166_G1.1981.00
259_W262_L1.1951.00
136_A147_F1.1911.00
387_A391_K1.1841.00
437_V440_S1.1761.00
428_I432_I1.1701.00
123_W127_I1.1681.00
36_I43_V1.1681.00
442_Y446_I1.1651.00
15_I234_A1.1621.00
401_F404_Y1.1571.00
412_M416_G1.1561.00
267_S271_S1.1511.00
225_K230_T1.1471.00
61_M74_F1.1471.00
148_E298_N1.1441.00
9_G225_K1.1431.00
88_Y92_W1.1381.00
19_A217_I1.1331.00
78_G86_A1.1291.00
124_I128_V1.1281.00
147_F151_F1.1261.00
18_I220_T1.1221.00
138_L329_V1.1181.00
70_S76_T1.1181.00
75_A310_T1.1161.00
429_V432_I1.1141.00
313_V322_K1.1051.00
161_L165_A1.1041.00
398_F401_F1.1001.00
339_I343_V1.1001.00
20_L241_R1.0971.00
411_L415_V1.0971.00
386_G392_H1.0921.00
146_E150_W1.0871.00
181_I184_S1.0841.00
324_I328_G1.0821.00
432_I439_I1.0751.00
65_L77_F1.0711.00
196_G199_G1.0691.00
63_E66_Y1.0631.00
332_Y335_I1.0591.00
390_D393_P1.0571.00
128_V132_I1.0541.00
407_I411_L1.0511.00
440_S443_V1.0491.00
399_A403_N1.0441.00
400_P404_Y1.0431.00
427_L430_G1.0421.00
378_H403_N1.0371.00
48_A247_I1.0331.00
201_F412_M1.0221.00
131_V135_A1.0131.00
20_L242_I1.0121.00
383_K400_P1.0071.00
113_T117_F1.0071.00
110_G125_P1.0031.00
134_G138_L1.0021.00
168_G172_F1.0001.00
66_Y393_P0.9991.00
440_S444_F0.9921.00
437_V441_Y0.9921.00
110_G126_G0.9881.00
141_V302_F0.9881.00
70_S80_Q0.9841.00
163_I167_I0.9831.00
160_I164_I0.9771.00
221_A231_L0.9761.00
113_T290_I0.9741.00
156_I245_F0.9731.00
67_V390_D0.9721.00
24_I27_G0.9701.00
183_L186_L0.9691.00
215_E219_I0.9671.00
182_G186_L0.9661.00
151_F295_S0.9631.00
375_L407_I0.9591.00
438_V442_Y0.9571.00
163_I252_V0.9541.00
138_L325_S0.9541.00
415_V419_F0.9541.00
301_I338_L0.9531.00
212_Q367_G0.9521.00
372_F376_I0.9501.00
56_F402_T0.9471.00
190_G194_A0.9441.00
17_M149_F0.9431.00
133_L298_N0.9421.00
325_S328_G0.9341.00
132_I294_M0.9221.00
237_S241_R0.9111.00
44_L254_V0.9061.00
104_S360_Y0.9051.00
277_G281_A0.9041.00
258_P275_K0.9001.00
155_K292_A0.9001.00
331_L335_I0.9001.00
72_G75_A0.8991.00
79_H314_N0.8981.00
243_L247_I0.8931.00
104_S209_A0.8901.00
372_F410_L0.8901.00
278_I281_A0.8851.00
72_G76_T0.8831.00
436_L440_S0.8821.00
179_D182_G0.8801.00
85_M89_I0.8791.00
9_G142_K0.8781.00
80_Q385_K0.8771.00
45_L200_F0.8751.00
51_G211_Y0.8741.00
256_V272_T0.8701.00
146_E149_F0.8701.00
414_L417_M0.8661.00
12_A234_A0.8661.00
197_F200_F0.8571.00
48_A52_I0.8561.00
109_V293_A0.8561.00
123_W345_V0.8561.00
267_S270_V0.8521.00
125_P128_V0.8511.00
13_R149_F0.8501.00
67_V393_P0.8481.00
167_I248_G0.8431.00
114_K122_A0.8421.00
14_H146_E0.8421.00
186_L189_H0.8351.00
109_V294_M0.8351.00
162_M273_F0.8351.00
130_M345_V0.8341.00
251_F255_T0.8341.00
379_I403_N0.8341.00
193_F196_G0.8331.00
212_Q371_W0.8331.00
107_I359_V0.8321.00
317_A321_F0.8281.00
170_I255_T0.8271.00
279_T283_G0.8261.00
180_A183_L0.8261.00
78_G377_S0.8231.00
338_L342_A0.8221.00
385_K390_D0.8221.00
92_W317_A0.8211.00
263_N268_P0.8191.00
216_L303_S0.8181.00
186_L190_G0.8171.00
55_F59_R0.8151.00
56_F60_A0.8141.00
387_A392_H0.8121.00
321_F332_Y0.8111.00
193_F200_F0.8101.00
110_G122_A0.8021.00
339_I342_A0.7981.00
306_R309_Y0.7951.00
170_I173_G0.7931.00
135_A138_L0.7911.00
133_L301_I0.7911.00
57_I410_L0.7891.00
86_A373_I0.7871.00
101_V363_S0.7861.00
432_I435_A0.7851.00
432_I437_V0.7851.00
412_M415_V0.7841.00
55_F236_Q0.7821.00
378_H382_R0.7801.00
232_R235_I0.7801.00
183_L255_T0.7781.00
168_G174_F0.7781.00
362_A366_P0.7771.00
429_V439_I0.7761.00
397_P401_F0.7731.00
137_N334_T0.7731.00
273_F276_I0.7711.00
391_K395_K0.7711.00
24_I155_K0.7701.00
379_I383_K0.7691.00
94_N98_W0.7681.00
430_G439_I0.7651.00
64_M378_H0.7631.00
59_R402_T0.7611.00
24_I29_F0.7611.00
379_I400_P0.7611.00
138_L327_N0.7601.00
23_T238_I0.7591.00
28_L249_A0.7571.00
163_I249_A0.7561.00
377_S381_F0.7561.00
99_I340_G0.7551.00
427_L431_V0.7541.00
172_F180_A0.7531.00
441_Y445_G0.7511.00
399_A402_T0.7501.00
431_V434_L0.7481.00
71_T309_Y0.7451.00
226_D232_R0.7431.00
64_M77_F0.7421.00
365_L430_G0.7401.00
202_F206_L0.7381.00
330_P333_G0.7371.00
75_A79_H0.7361.00
67_V386_G0.7351.00
82_I377_S0.7321.00
16_Q234_A0.7301.00
428_I431_V0.7281.00
139_I143_S0.7271.00
110_G113_T0.7231.00
35_T39_T0.7221.00
366_P370_P0.7211.00
83_H445_G0.7191.00
190_G193_F0.7191.00
301_I305_G0.7171.00
392_H395_K0.7171.00
180_A184_S0.7161.00
427_L432_I0.7161.00
45_L48_A0.7131.00
56_F406_T0.7131.00
222_G309_Y0.7121.00
326_R331_L0.7111.00
13_R146_E0.7101.00
438_V441_Y0.7081.00
119_D122_A0.7081.00
305_G333_G0.7061.00
413_V417_M0.7061.00
25_G29_F0.7051.00
45_L49_I0.7041.00
406_T410_L0.7031.00
133_L294_M0.7011.00
54_I214_V0.6991.00
81_Y380_G0.6981.00
61_M374_I0.6941.00
85_M438_V0.6941.00
31_G360_Y0.6921.00
137_N302_F0.6921.00
439_I442_Y0.6911.00
127_I346_V0.6911.00
141_V220_T0.6901.00
9_G141_V0.6901.00
145_G298_N0.6891.00
143_S146_E0.6881.00
123_W126_G0.6881.00
273_F278_I0.6871.00
100_I362_A0.6871.00
41_P254_V0.6871.00
248_G252_V0.6861.00
437_V444_F0.6821.00
21_G152_A0.6791.00
60_A406_T0.6791.00
430_G435_A0.6791.00
241_R245_F0.6791.00
432_I443_V0.6771.00
308_L336_A0.6771.00
414_L427_L0.6771.00
47_Y210_A0.6761.00
396_M402_T0.6761.00
44_L48_A0.6751.00
433_F440_S0.6741.00
396_M399_A0.6731.00
179_D183_L0.6721.00
32_S250_I0.6721.00
321_F333_G0.6711.00
268_P273_F0.6691.00
145_G149_F0.6691.00
43_V250_I0.6631.00
129_A297_C0.6631.00
58_M214_V0.6621.00
105_E297_C0.6611.00
199_G202_F0.6601.00
237_S240_W0.6601.00
103_M359_V0.6601.00
320_F336_A0.6601.00
249_A253_I0.6591.00
435_A438_V0.6581.00
101_V104_S0.6541.00
186_L191_G0.6531.00
112_Y289_V0.6521.00
312_G321_F0.6521.00
228_Q393_P0.6511.00
97_Q367_G0.6501.00
49_I204_L0.6491.00
9_G13_R0.6481.00
60_A396_M0.6471.00
131_V134_G0.6471.00
81_Y381_F0.6471.00
324_I327_N0.6471.00
382_R386_G0.6451.00
386_G390_D0.6451.00
212_Q215_E0.6451.00
441_Y444_F0.6451.00
430_G436_L0.6431.00
75_A91_A0.6421.00
201_F416_G0.6411.00
75_A87_G0.6411.00
59_R397_P0.6401.00
115_Y286_N0.6401.00
74_F215_E0.6401.00
403_N407_I0.6391.00
13_R16_Q0.6381.00
65_L231_L0.6381.00
390_D395_K0.6381.00
223_E324_I0.6381.00
429_V433_F0.6361.00
116_W286_N0.6361.00
188_S191_G0.6351.00
93_S370_P0.6341.00
106_I110_G0.6341.00
101_V105_E0.6341.00
22_G299_S0.6321.00
434_L437_V0.6311.00
383_K386_G0.6301.00
116_W287_F0.6291.00
154_I158_T0.6291.00
189_H192_F0.6281.00
252_V255_T0.6261.00
440_S445_G0.6261.00
113_T129_A0.6241.00
186_L192_F0.6231.00
191_G194_A0.6201.00
218_G235_I0.6201.00
98_W300_G0.6201.00
231_L235_I0.6191.00
223_E330_P0.6171.00
306_R324_I0.6171.00
25_G246_Y0.6161.00
280_A283_G0.6161.00
140_S143_S0.6151.00
439_I444_F0.6151.00
64_M81_Y0.6151.00
130_M342_A0.6151.00
65_L218_G0.6141.00
103_M344_G0.6121.00
62_G66_Y0.6121.00
74_F219_I0.6111.00
263_N267_S0.6111.00
346_V349_Y0.6101.00
157_V160_I0.6101.00
34_S357_V0.6101.00
44_L247_I0.6091.00
400_P403_N0.6081.00
382_R399_A0.6051.00
292_A295_S0.6051.00
219_I303_S0.6051.00
439_I445_G0.6051.00
154_I288_V0.6031.00
108_A112_Y0.6031.00
24_I245_F0.6021.00
16_Q19_A0.6011.00
22_G300_G0.5991.00
406_T409_F0.5981.00
132_I136_A0.5981.00
304_A308_L0.5981.00
224_A231_L0.5971.00
336_A340_G0.5961.00
17_M152_A0.5951.00
138_L334_T0.5941.00
241_R244_I0.5931.00
381_F392_H0.5911.00
26_V209_A0.5911.00
227_P230_T0.5901.00
433_F436_L0.5901.00
38_W202_F0.5891.00
433_F439_I0.5871.00
272_T276_I0.5851.00
93_S369_I0.5841.00
134_G301_I0.5841.00
387_A390_D0.5841.00
210_A246_Y0.5841.00
404_Y407_I0.5801.00
158_T284_I0.5801.00
99_I337_V0.5801.00
105_E293_A0.5791.00
24_I31_G0.5791.00
287_F291_T0.5791.00
20_L152_A0.5781.00
50_C208_I0.5771.00
435_A442_Y0.5771.00
58_M62_G0.5761.00
410_L413_V0.5751.00
144_F302_F0.5741.00
149_F153_M0.5741.00
83_H87_G0.5711.00
152_A155_K0.5701.00
184_S188_S0.5701.00
29_F159_I0.5641.00
19_A23_T0.5641.00
57_I215_E0.5641.00
50_C211_Y0.5631.00
170_I252_V0.5631.00
212_Q363_S0.5631.00
357_V360_Y0.5631.00
241_R248_G0.5631.00
114_K118_P0.5621.00
379_I407_I0.5621.00
415_V418_W0.5621.00
78_G87_G0.5601.00
90_T370_P0.5601.00
30_M33_A0.5591.00
143_S147_F0.5591.00
368_M410_L0.5591.00
8_R225_K0.5571.00
41_P44_L0.5541.00
35_T207_V0.5541.00
105_E108_A0.5511.00
365_L414_L0.5501.00
73_S218_G0.5501.00
268_P276_I0.5471.00
228_Q391_K0.5471.00
398_F403_N0.5461.00
372_F414_L0.5461.00
148_E295_S0.5461.00
308_L312_G0.5461.00
194_A259_W0.5451.00
131_V335_I0.5431.00
193_F197_F0.5401.00
150_W153_M0.5401.00
128_V131_V0.5381.00
394_F397_P0.5371.00
129_A133_L0.5371.00
120_L125_P0.5351.00
44_L47_Y0.5351.00
301_I334_T0.5341.00
103_M341_L0.5341.00
93_S97_Q0.5321.00
42_S192_F0.5321.00
165_A278_I0.5321.00
99_I344_G0.5311.00
38_W203_A0.5301.00
320_F324_I0.5281.00
284_I288_V0.5281.00
141_V145_G0.5281.00
306_R330_P0.5281.00
97_Q366_P0.5281.00
67_V381_F0.5271.00
228_Q233_N0.5251.00
408_A411_L0.5241.00
47_Y250_I0.5241.00
18_I21_G0.5231.00
215_E371_W0.5221.00
35_T203_A0.5211.00
297_C300_G0.5201.00
223_E309_Y0.5191.00
70_S222_G0.5191.00
428_I433_F0.5181.00
224_A234_A0.5181.00
122_A126_G0.5181.00
431_V436_L0.5171.00
47_Y246_Y0.5161.00
367_G370_P0.5161.00
105_E110_G0.5151.00
55_F239_I0.5141.00
427_L439_I0.5141.00
29_F155_K0.5141.00
386_G393_P0.5131.00
396_M403_N0.5121.00
273_F281_A0.5121.00
229_N232_R0.5121.00
11_G142_K0.5111.00
111_S122_A0.5101.00
63_E67_V0.5101.00
15_I220_T0.5101.00
227_P231_L0.5071.00
39_T46_A0.5061.00
109_V113_T0.5061.00
343_V346_V0.5051.00
429_V436_L0.5051.00
257_Y261_E0.5041.00
34_S37_S0.5031.00
129_A294_M0.5031.00
19_A22_G0.5021.00
13_R153_M0.5011.00
116_W290_I0.5001.00
154_I291_T0.5001.00
62_G235_I0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3l1lA 2 0.9026 100 0.253 Contact Map
4djkA 2 0.8874 100 0.332 Contact Map
3giaA 1 0.9177 100 0.334 Contact Map
3dh4A 3 0.9242 99 0.85 Contact Map
2xq2A 2 0.9264 99 0.852 Contact Map
2jlnA 1 0.9026 98.8 0.863 Contact Map
4wgvA 2 0.7771 97.8 0.895 Contact Map
4us3A 1 0.8333 97.8 0.895 Contact Map
2a65A 2 0.9264 97.7 0.897 Contact Map
4xp4A 1 0.9286 97.3 0.905 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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