GREMLIN Database
GGT - Gamma-glutamyltranspeptidase
UniProt: P54422 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 587 (522)
Sequences: 5235 (3609)
Seq/√Len: 158.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
178_E230_K7.0301.00
238_D242_K4.3731.00
307_H362_Q4.2621.00
66_K168_Q3.7991.00
247_K262_E3.7051.00
175_K179_K3.6401.00
303_K358_I3.5221.00
48_M569_G3.5101.00
51_T57_S3.1561.00
51_T77_I3.0051.00
112_S153_G2.9951.00
250_S262_E2.8591.00
325_A524_Y2.7951.00
280_Y502_E2.7511.00
188_A216_E2.5801.00
561_D564_N2.5681.00
303_K355_P2.4651.00
506_E509_A2.4461.00
102_G414_N2.4271.00
80_A176_L2.3901.00
306_D355_P2.3481.00
281_Q502_E2.3441.00
60_G77_I2.2871.00
499_Y505_M2.2831.00
507_L557_S2.2801.00
307_H359_K2.2531.00
537_K541_M2.2031.00
286_A472_F2.2031.00
110_I272_I2.1961.00
318_W537_K2.1921.00
319_E541_M2.1891.00
155_E159_D2.1851.00
79_F170_I2.1801.00
174_I233_R2.1791.00
97_M157_A2.1661.00
171_T175_K2.1621.00
49_V60_G2.1491.00
239_A245_F2.1461.00
536_S539_N2.1341.00
155_E237_T2.1241.00
279_D284_Q2.1211.00
77_I406_F2.1211.00
253_V258_G2.1171.00
415_V480_T2.0991.00
301_M494_L2.0981.00
156_E270_I2.0741.00
212_E218_D2.0681.00
108_T161_W2.0361.00
277_W284_Q2.0351.00
322_Q543_H2.0241.00
46_D411_R2.0181.00
231_L244_K1.9951.00
160_K272_I1.9541.00
242_K266_E1.9541.00
497_I501_I1.9421.00
106_D274_E1.9121.00
511_V557_S1.9101.00
471_L497_I1.9101.00
215_K218_D1.8971.00
62_D65_K1.8801.00
235_K239_A1.8751.00
366_N369_Q1.8671.00
304_I327_T1.8591.00
231_L235_K1.8441.00
224_D434_D1.8421.00
109_I288_T1.8331.00
409_A567_F1.8271.00
296_I339_A1.8261.00
271_T343_E1.8241.00
230_K234_S1.8211.00
57_S580_I1.7951.00
278_G299_L1.7861.00
231_L239_A1.7801.00
247_K251_D1.7781.00
263_K267_N1.7661.00
71_I157_A1.7661.00
152_K270_I1.7611.00
178_E227_K1.7521.00
167_K234_S1.7491.00
195_Q199_S1.7461.00
277_W286_A1.7431.00
118_A267_N1.7351.00
75_V158_L1.7341.00
409_A415_V1.7211.00
62_D66_K1.7101.00
360_E363_Q1.6681.00
151_L232_I1.6681.00
156_E159_D1.6571.00
58_E62_D1.6531.00
508_K512_E1.6531.00
479_L559_S1.6461.00
512_E573_S1.6301.00
84_T181_F1.6241.00
479_L500_H1.6151.00
163_T412_W1.6151.00
407_T480_T1.6111.00
250_S254_Q1.6001.00
49_V77_I1.5961.00
508_K570_V1.5921.00
62_D175_K1.5741.00
100_Y107_T1.5661.00
323_L367_L1.5581.00
158_L169_L1.5421.00
77_I408_V1.5061.00
158_L166_M1.5051.00
115_R268_Y1.5041.00
142_G253_V1.4921.00
320_K503_Y1.4841.00
298_L467_T1.4821.00
231_L245_F1.4721.00
313_Y323_L1.4721.00
185_S216_E1.4681.00
63_V164_R1.4681.00
415_V477_P1.4661.00
250_S261_T1.4631.00
95_G153_G1.4531.00
170_I174_I1.4521.00
498_L502_E1.4511.00
156_E272_I1.4451.00
165_S168_Q1.4441.00
119_G261_T1.4391.00
535_L539_N1.4311.00
278_G303_K1.4301.00
116_A459_N1.4301.00
496_T555_V1.4271.00
100_Y105_K1.4211.00
182_P219_T1.4141.00
309_N312_Q1.4061.00
421_T442_E1.4011.00
554_N575_R1.3971.00
202_A205_D1.3951.00
71_I99_V1.3931.00
96_F291_P1.3911.00
174_I230_K1.3901.00
155_E166_M1.3841.00
251_D255_D1.3701.00
537_K540_G1.3621.00
326_E329_H1.3611.00
61_A65_K1.3601.00
119_G259_S1.3571.00
559_S568_K1.3531.00
152_K237_T1.3491.00
322_Q326_E1.3441.00
359_K362_Q1.3371.00
308_F362_Q1.3351.00
63_V66_K1.3341.00
107_T286_A1.3341.00
262_E266_E1.3201.00
141_K430_I1.3201.00
158_L163_T1.3191.00
303_K306_D1.3141.00
253_V260_M1.3111.00
560_I567_F1.3091.00
361_R364_L1.3031.00
248_T435_Y1.3001.00
109_I289_P1.2991.00
63_V169_L1.2941.00
279_D282_G1.2911.00
244_K247_K1.2911.00
526_Y535_L1.2861.00
111_D273_D1.2801.00
285_I471_L1.2801.00
267_N459_N1.2791.00
50_A556_Q1.2781.00
145_V439_L1.2731.00
532_K536_S1.2701.00
499_Y503_Y1.2681.00
563_E566_T1.2591.00
500_H559_S1.2591.00
536_S540_G1.2541.00
152_K238_D1.2511.00
330_L364_L1.2481.00
118_A459_N1.2411.00
95_G112_S1.2381.00
71_I416_V1.2301.00
366_N370_V1.2171.00
495_Q515_R1.2071.00
535_L545_F1.2011.00
561_D568_K1.1981.00
61_A580_I1.1941.00
505_M513_E1.1931.00
66_K164_R1.1861.00
168_Q171_T1.1851.00
108_T160_K1.1811.00
283_Y478_V1.1811.00
59_I80_A1.1801.00
98_M109_I1.1791.00
147_V260_M1.1721.00
110_I157_A1.1691.00
242_K246_A1.1611.00
305_L494_L1.1611.00
321_Y325_A1.1601.00
499_Y513_E1.1591.00
319_E367_L1.1581.00
298_L494_L1.1581.00
473_K476_K1.1541.00
71_I414_N1.1481.00
110_I270_I1.1481.00
449_I452_G1.1471.00
214_L218_D1.1461.00
318_W541_M1.1451.00
201_T205_D1.1441.00
108_T272_I1.1411.00
344_F460_K1.1381.00
283_Y501_I1.1361.00
301_M327_T1.1341.00
99_V157_A1.1341.00
301_M328_M1.1311.00
500_H507_L1.1271.00
308_F323_L1.1251.00
318_W534_V1.1241.00
204_K208_L1.1231.00
69_N163_T1.1231.00
115_R459_N1.1221.00
51_T60_G1.1181.00
156_E269_D1.1171.00
100_Y472_F1.1171.00
41_V506_E1.1141.00
205_D224_D1.1081.00
355_P359_K1.1021.00
263_K266_E1.1011.00
326_E543_H1.0990.99
334_D361_R1.0940.99
110_I161_W1.0900.99
63_V76_A1.0880.99
278_G355_P1.0860.99
472_F477_P1.0860.99
156_E160_K1.0850.99
406_F418_Y1.0850.99
317_S320_K1.0850.99
321_Y534_V1.0820.99
252_T432_V1.0820.99
309_N313_Y1.0810.99
166_M169_L1.0740.99
74_A416_V1.0740.99
478_V559_S1.0690.99
432_V439_L1.0690.99
178_E223_K1.0690.99
56_A81_L1.0640.99
75_V169_L1.0610.99
151_L237_T1.0600.99
62_D172_P1.0590.99
171_T174_I1.0590.99
334_D357_Y1.0580.99
152_K156_E1.0560.99
296_I349_L1.0540.99
228_T437_V1.0480.99
158_L165_S1.0450.99
481_V496_T1.0440.99
118_A263_K1.0370.99
142_G256_F1.0370.99
97_M153_G1.0350.99
75_V154_L1.0350.99
166_M170_I1.0350.99
284_Q472_F1.0300.99
535_L547_T1.0280.99
248_T251_D1.0260.99
314_D317_S1.0240.99
377_G380_W1.0210.99
227_K230_K1.0210.99
43_V568_K1.0180.99
188_A215_K1.0130.99
507_L570_V1.0130.99
457_Q460_K1.0120.99
405_H417_S1.0100.99
63_V168_Q1.0090.99
111_D291_P1.0060.99
299_L353_L1.0010.99
480_T558_I1.0010.99
120_A124_M0.9970.99
149_G268_Y0.9960.99
477_P480_T0.9950.99
63_V172_P0.9930.99
285_I302_L0.9930.99
374_P377_G0.9920.99
47_G64_L0.9880.99
244_K248_T0.9830.99
260_M265_L0.9830.99
82_N225_L0.9820.99
569_G579_A0.9800.99
48_M567_F0.9800.99
300_Q334_D0.9800.99
122_P457_Q0.9790.99
122_P455_E0.9780.99
345_V348_P0.9780.99
304_I307_H0.9760.99
79_F151_L0.9750.99
445_D487_A0.9730.99
320_K324_L0.9690.99
113_R291_P0.9680.99
301_M331_S0.9660.99
409_A558_I0.9650.99
310_L313_Y0.9650.99
50_A571_A0.9630.99
248_T434_D0.9620.99
422_I438_I0.9620.99
78_Q420_T0.9600.99
534_V537_K0.9590.99
58_E65_K0.9590.99
103_K106_D0.9590.99
53_H84_T0.9570.99
212_E215_K0.9540.99
134_P138_R0.9480.99
245_F248_T0.9480.99
415_V470_I0.9470.98
48_M558_I0.9430.98
55_L59_I0.9410.98
52_A85_E0.9410.98
405_H482_G0.9390.98
483_S492_S0.9370.98
476_K560_I0.9370.98
454_N460_K0.9350.98
59_I173_S0.9310.98
451_G455_E0.9310.98
152_K155_E0.9300.98
145_V430_I0.9270.98
488_T492_S0.9260.98
227_K234_S0.9250.98
228_T245_F0.9240.98
188_A192_S0.9200.98
192_S215_K0.9200.98
283_Y473_K0.9190.98
330_L361_R0.9170.98
281_Q308_F0.9160.98
310_L498_L0.9150.98
187_L191_I0.9140.98
246_A265_L0.9130.98
74_A408_V0.9130.98
473_K478_V0.9130.98
183_I188_A0.9120.98
302_L497_I0.9120.98
222_Q437_V0.9100.98
59_I76_A0.9070.98
178_E226_A0.9060.98
432_V435_Y0.9050.98
511_V555_V0.9050.98
321_Y530_V0.9030.98
158_L164_R0.9020.98
126_L450_P0.8980.98
304_I362_Q0.8980.98
203_A438_I0.8980.98
304_I365_I0.8940.98
185_S189_E0.8930.98
252_T255_D0.8920.98
227_K231_L0.8920.98
526_Y530_V0.8920.98
447_D450_P0.8920.98
112_S418_Y0.8870.98
526_Y545_F0.8840.98
80_A84_T0.8810.98
249_L439_L0.8810.98
531_P535_L0.8760.98
320_K498_L0.8750.97
317_S503_Y0.8730.97
164_R168_Q0.8730.97
44_G48_M0.8710.97
165_S169_L0.8690.97
41_V568_K0.8620.97
404_T420_T0.8600.97
206_V222_Q0.8590.97
50_A558_I0.8550.97
110_I156_E0.8520.97
319_E323_L0.8510.97
246_A262_E0.8510.97
279_D306_D0.8470.97
471_L479_L0.8470.97
410_D414_N0.8460.97
340_G462_P0.8440.97
45_K566_T0.8440.97
208_L214_L0.8430.97
248_T433_P0.8420.97
250_S253_V0.8420.97
355_P358_I0.8400.97
120_A259_S0.8400.97
225_L229_F0.8390.97
82_N229_F0.8370.97
145_V428_T0.8360.97
539_N544_K0.8350.97
447_D455_E0.8320.97
116_A120_A0.8280.96
252_T430_I0.8260.96
83_V177_A0.8250.96
164_R169_L0.8240.96
366_N371_N0.8210.96
142_G252_T0.8180.96
409_A560_I0.8180.96
89_S420_T0.8180.96
526_Y547_T0.8170.96
281_Q501_I0.8160.96
344_F457_Q0.8160.96
481_V557_S0.8150.96
469_T481_V0.8150.96
278_G358_I0.8140.96
525_R546_G0.8130.96
354_H358_I0.8120.96
209_P212_E0.8080.96
222_Q225_L0.8070.96
83_V173_S0.8070.96
115_R343_E0.8050.96
491_S517_Y0.8030.96
252_T256_F0.8030.96
101_D108_T0.8010.96
143_T259_S0.7990.96
124_M128_E0.7970.96
531_P534_V0.7970.96
275_P286_A0.7950.96
183_I220_L0.7950.96
505_M509_A0.7930.96
245_F437_V0.7910.95
351_G379_P0.7900.95
253_V439_L0.7890.95
120_A125_F0.7890.95
95_G418_Y0.7880.95
423_E445_D0.7830.95
232_I237_T0.7830.95
114_E442_E0.7800.95
328_M494_L0.7760.95
228_T435_Y0.7720.95
279_D355_P0.7680.95
124_M259_S0.7650.95
201_T204_K0.7640.95
183_I214_L0.7620.94
115_R271_T0.7600.94
276_I287_T0.7580.94
123_D126_L0.7550.94
59_I176_L0.7550.94
315_V505_M0.7540.94
110_I160_K0.7520.94
245_F249_L0.7520.94
357_Y361_R0.7490.94
281_Q306_D0.7490.94
298_L493_V0.7470.94
203_A431_M0.7470.94
183_I187_L0.7460.94
76_A169_L0.7460.94
127_D130_G0.7450.94
287_T493_V0.7420.94
324_L516_I0.7420.94
49_V64_L0.7400.94
304_I358_I0.7400.94
305_L310_L0.7390.94
122_P126_L0.7380.93
92_G437_V0.7380.93
174_I178_E0.7370.93
256_F430_I0.7370.93
539_N547_T0.7350.93
126_L130_G0.7340.93
321_Y516_I0.7340.93
55_L84_T0.7330.93
55_L182_P0.7330.93
287_T467_T0.7320.93
479_L507_L0.7320.93
304_I361_R0.7320.93
83_V225_L0.7280.93
273_D289_P0.7280.93
146_G443_L0.7270.93
64_L408_V0.7260.93
253_V256_F0.7260.93
423_E444_T0.7240.93
148_P439_L0.7240.93
228_T231_L0.7220.93
239_A244_K0.7220.93
287_T469_T0.7210.93
96_F292_S0.7200.93
78_Q406_F0.7200.93
478_V500_H0.7200.93
199_S204_K0.7180.93
77_I80_A0.7150.92
359_K363_Q0.7140.92
527_E574_S0.7120.92
471_L501_I0.7090.92
59_I63_V0.7090.92
57_S77_I0.7090.92
57_S578_A0.7080.92
311_S504_G0.7080.92
470_I477_P0.7070.92
44_G47_G0.7050.92
284_Q475_D0.7050.92
184_D576_N0.7040.92
60_G408_V0.7040.92
100_Y103_K0.7020.92
558_I567_F0.7020.92
322_Q365_I0.7010.92
55_L176_L0.6980.91
223_K227_K0.6980.91
98_M470_I0.6980.91
424_Q441_N0.6980.91
209_P214_L0.6960.91
481_V497_I0.6950.91
99_V416_V0.6950.91
85_E554_N0.6940.91
449_I455_E0.6940.91
319_E537_K0.6940.91
287_T298_L0.6930.91
99_V414_N0.6920.91
238_D266_E0.6920.91
57_S61_A0.6920.91
328_M491_S0.6910.91
94_G114_E0.6900.91
283_Y471_L0.6890.91
91_I151_L0.6890.91
432_V437_V0.6880.91
91_I232_I0.6880.91
125_F141_K0.6880.91
96_F464_S0.6860.91
132_A135_F0.6860.91
326_E365_I0.6850.91
248_T432_V0.6840.91
138_R448_A0.6800.90
55_L58_E0.6800.90
53_H184_D0.6790.90
58_E61_A0.6760.90
191_I208_L0.6760.90
322_Q329_H0.6750.90
78_Q418_Y0.6750.90
507_L568_K0.6740.90
278_G306_D0.6730.90
58_E580_I0.6720.90
120_A456_V0.6720.90
107_T472_F0.6710.90
177_A226_A0.6710.90
324_L498_L0.6700.90
102_G105_K0.6700.90
119_G254_Q0.6690.90
288_T292_S0.6680.90
366_N541_M0.6670.89
254_Q261_T0.6660.89
150_T420_T0.6640.89
367_L541_M0.6620.89
532_K547_T0.6610.89
157_A416_V0.6610.89
71_I101_D0.6610.89
314_D320_K0.6610.89
75_V170_I0.6610.89
224_D227_K0.6560.89
285_I469_T0.6550.89
47_G61_A0.6540.89
155_E236_G0.6530.88
409_A480_T0.6530.88
297_F335_R0.6530.88
284_Q473_K0.6520.88
57_S579_A0.6510.88
351_G354_H0.6490.88
311_S314_D0.6480.88
249_L265_L0.6480.88
206_V431_M0.6470.88
116_A446_F0.6470.88
191_I214_L0.6460.88
276_I339_A0.6460.88
308_F365_I0.6440.88
498_L503_Y0.6430.88
330_L371_N0.6430.88
240_F246_A0.6430.88
500_H504_G0.6420.88
125_F144_A0.6410.88
124_M127_D0.6410.88
192_S195_Q0.6410.88
114_E146_G0.6390.87
362_Q365_I0.6380.87
301_M491_S0.6370.87
142_G430_I0.6360.87
108_T274_E0.6360.87
155_E158_L0.6360.87
79_F166_M0.6350.87
141_K428_T0.6330.87
314_D503_Y0.6310.87
152_K268_Y0.6310.87
556_Q571_A0.6300.87
171_T233_R0.6290.87
340_G345_V0.6290.87
340_G453_A0.6280.86
140_T143_T0.6260.86
102_G412_W0.6250.86
123_D127_D0.6250.86
371_N376_A0.6250.86
407_T558_I0.6250.86
100_Y477_P0.6240.86
315_V320_K0.6240.86
141_K144_A0.6230.86
195_Q208_L0.6230.86
118_A261_T0.6220.86
195_Q212_E0.6200.86
448_A456_V0.6200.86
75_V162_G0.6180.86
202_A252_T0.6170.86
500_H510_A0.6170.86
300_Q357_Y0.6130.85
181_F220_L0.6130.85
60_G80_A0.6130.85
511_V570_V0.6120.85
69_N412_W0.6110.85
79_F154_L0.6100.85
43_V566_T0.6090.85
507_L511_V0.6090.85
335_R339_A0.6080.85
173_S177_A0.6080.85
114_E465_S0.6080.85
297_F339_A0.6070.85
533_D536_S0.6070.85
113_R445_D0.6060.85
322_Q541_M0.6060.85
59_I62_D0.6050.84
322_Q367_L0.6050.84
316_R320_K0.6050.84
351_G380_W0.6050.84
467_T493_V0.6040.84
297_F331_S0.6040.84
431_M438_I0.6030.84
235_K244_K0.6030.84
307_H355_P0.6030.84
492_S555_V0.6020.84
96_F113_R0.6010.84
208_L213_P0.6010.84
561_D566_T0.6000.84
273_D343_E0.6000.84
190_A425_L0.6000.84
440_N443_L0.5990.84
82_N90_G0.5990.84
305_L323_L0.5990.84
488_T552_I0.5980.84
60_G76_A0.5970.84
356_D360_E0.5960.84
99_V108_T0.5960.84
300_Q304_I0.5960.84
360_E364_L0.5950.83
254_Q260_M0.5950.83
313_Y320_K0.5940.83
442_E465_S0.5940.83
80_A173_S0.5930.83
117_P120_A0.5920.83
495_Q499_Y0.5920.83
170_I233_R0.5920.83
134_P137_E0.5910.83
196_E199_S0.5910.83
47_G411_R0.5910.83
97_M112_S0.5900.83
115_R118_A0.5890.83
150_T421_T0.5890.83
481_V493_V0.5870.83
405_H419_T0.5860.83
163_T169_L0.5850.82
78_Q150_T0.5840.82
101_D414_N0.5830.82
469_T497_I0.5820.82
82_N89_S0.5820.82
187_L220_L0.5810.82
81_L404_T0.5790.82
202_A433_P0.5790.82
523_S544_K0.5790.82
78_Q154_L0.5790.82
85_E88_M0.5780.82
111_D271_T0.5770.82
276_I299_L0.5750.81
219_T566_T0.5750.81
76_A173_S0.5740.81
353_L358_I0.5730.81
52_A404_T0.5730.81
81_L406_F0.5720.81
113_R464_S0.5710.81
530_V535_L0.5710.81
571_A575_R0.5710.81
419_T489_I0.5700.81
415_V560_I0.5690.81
70_A416_V0.5690.81
305_L324_L0.5680.81
250_S260_M0.5670.80
239_A242_K0.5660.80
144_A428_T0.5660.80
492_S553_G0.5650.80
332_Y490_I0.5650.80
488_T517_Y0.5640.80
301_M490_I0.5630.80
71_I97_M0.5630.80
115_R461_R0.5620.80
327_T331_S0.5610.80
324_L327_T0.5600.80
251_D434_D0.5580.79
253_V265_L0.5570.79
488_T491_S0.5560.79
477_P560_I0.5550.79
140_T197_K0.5540.79
95_G150_T0.5540.79
528_D547_T0.5540.79
94_G113_R0.5530.79
88_M422_I0.5510.79
98_M275_P0.5500.78
69_N164_R0.5500.78
280_Y310_L0.5490.78
516_I530_V0.5490.78
98_M288_T0.5490.78
408_V416_V0.5490.78
133_I137_E0.5480.78
445_D465_S0.5470.78
327_T365_I0.5470.78
571_A579_A0.5460.78
419_T464_S0.5460.78
101_D106_D0.5450.78
409_A477_P0.5450.78
63_V77_I0.5440.78
518_T524_Y0.5430.78
41_V570_V0.5430.78
500_H557_S0.5430.78
224_D431_M0.5420.77
207_F222_Q0.5420.77
236_G239_A0.5410.77
483_S553_G0.5400.77
407_T417_S0.5400.77
273_D288_T0.5400.77
259_S456_V0.5400.77
98_M107_T0.5400.77
113_R442_E0.5390.77
59_I172_P0.5380.77
216_E219_T0.5380.77
249_L437_V0.5380.77
189_E193_D0.5380.77
452_G455_E0.5360.77
94_G464_S0.5340.76
97_M416_V0.5340.76
310_L323_L0.5330.76
478_V560_I0.5330.76
539_N545_F0.5330.76
133_I138_R0.5330.76
226_A230_K0.5320.76
519_N522_S0.5310.76
85_E90_G0.5310.76
188_A213_P0.5310.76
179_K230_K0.5290.76
84_T141_K0.5280.76
442_E489_I0.5270.75
195_Q213_P0.5270.75
46_D65_K0.5250.75
152_K242_K0.5250.75
145_V253_V0.5230.75
445_D464_S0.5220.75
310_L503_Y0.5210.75
287_T490_I0.5210.75
324_L328_M0.5210.75
87_M187_L0.5200.74
142_G145_V0.5200.74
114_E445_D0.5190.74
300_Q358_I0.5180.74
196_E200_R0.5180.74
221_I224_D0.5180.74
91_I437_V0.5180.74
109_I273_D0.5170.74
94_G489_I0.5170.74
292_S466_M0.5160.74
298_L469_T0.5160.74
228_T433_P0.5150.74
492_S552_I0.5150.74
443_L446_F0.5140.74
374_P524_Y0.5140.74
116_A457_Q0.5130.73
94_G466_M0.5130.73
315_V503_Y0.5130.73
484_P575_R0.5120.73
161_W272_I0.5120.73
155_E169_L0.5110.73
361_R377_G0.5110.73
117_P258_G0.5100.73
230_K233_R0.5100.73
146_G440_N0.5100.73
45_K219_T0.5100.73
531_P536_S0.5090.73
105_K476_K0.5090.73
328_M516_I0.5080.73
153_G270_I0.5080.73
114_E423_E0.5070.73
507_L559_S0.5060.72
479_L557_S0.5060.72
517_Y520_S0.5050.72
184_D569_G0.5050.72
121_T124_M0.5040.72
75_V82_N0.5030.72
364_L377_G0.5030.72
103_K107_T0.5020.72
87_M190_A0.5010.72
285_I497_I0.5010.72
454_N463_L0.5000.72
93_G440_N0.5000.72
252_T435_Y0.5000.72
465_S489_I0.5000.72
297_F336_A0.5000.72
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2e0wA 1 0.8484 100 0.085 Contact Map
2nlzA 4 0.9012 100 0.098 Contact Map
2i3oA 2 0.862 100 0.119 Contact Map
3whrA 1 0.6116 100 0.361 Contact Map
2dg5A 1 0.5911 100 0.419 Contact Map
2qmcA 1 0.586 100 0.424 Contact Map
4gdxA 1 0.569 100 0.427 Contact Map
3g9kL 1 0.4821 100 0.466 Contact Map
3whrB 1 0.3118 100 0.66 Contact Map
4gdxB 1 0.3032 100 0.673 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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