GGT - BACSU - GREMLIN Contacts

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GGT - Gamma-glutamyltranspeptidase

UniProt:	P54422	Sequences: MKRTWNVCLTALLSVLLVAGSVPFHAEAKKPPKSYDEYKQVDVGKDGMVATAHPLASEIGADVLKKGGNAIDAAVAIQFALNVTEPMMSGIGGGGFMMVYDGKTKDTTIIDSRERAPAGATPDMFLDENGKAIPFSERVTKGTAVGVPGTLKGLEEALDKWGTRSMKQLITPSIKLAEKGFPIDSVLAEAISDYQEKLSRTAAKDVFLPNGEPLKEGDTLIQKDLAKTFKLIRSKGTDAFYKGKFAKTLSDTVQDFGGSMTEKDLENYDITIDEPIWGDYQGYQIATTPPPSSGGIFLLQMLKILDHFNLSQYDVRSWEKYQLLAETMHLSYADRASYAGDPEFVNVPLKGLLHPDYIKERQQLINLDQVNKKPKAGDPWKYQEGSANYKQVEQPKDKVEGQTTHFTVADRWGNVVSYTTTIEQLFGTGIMVPDYGVILNNELTDFDAIPGGANEVQPNKRPLSSMTPTILFKDDKPVLTVGSPGGATIISSVLQTILYHIEYGMELKAAVEEPRIYTNSMSSYRYEDGVPKDVLSKLNGMGHKFGTSPVDIGNVQSISIDHENGTFKGVADSSRNGAAIGINLKRK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	587 (522)
Sequences:	5235 (3609)
Seq/√Len:	158.0

ECOLI - GGT
BACSU - GGT YWRD
SULSO - Q97TX5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
178_E	230_K	7.030	1.00
238_D	242_K	4.373	1.00
307_H	362_Q	4.262	1.00
66_K	168_Q	3.799	1.00
247_K	262_E	3.705	1.00
175_K	179_K	3.640	1.00
303_K	358_I	3.522	1.00
48_M	569_G	3.510	1.00
51_T	57_S	3.156	1.00
51_T	77_I	3.005	1.00
112_S	153_G	2.995	1.00
250_S	262_E	2.859	1.00
325_A	524_Y	2.795	1.00
280_Y	502_E	2.751	1.00
188_A	216_E	2.580	1.00
561_D	564_N	2.568	1.00
303_K	355_P	2.465	1.00
506_E	509_A	2.446	1.00
102_G	414_N	2.427	1.00
80_A	176_L	2.390	1.00
306_D	355_P	2.348	1.00
281_Q	502_E	2.344	1.00
60_G	77_I	2.287	1.00
499_Y	505_M	2.283	1.00
507_L	557_S	2.280	1.00
307_H	359_K	2.253	1.00
537_K	541_M	2.203	1.00
286_A	472_F	2.203	1.00
110_I	272_I	2.196	1.00
318_W	537_K	2.192	1.00
319_E	541_M	2.189	1.00
155_E	159_D	2.185	1.00
79_F	170_I	2.180	1.00
174_I	233_R	2.179	1.00
97_M	157_A	2.166	1.00
171_T	175_K	2.162	1.00
49_V	60_G	2.149	1.00
239_A	245_F	2.146	1.00
536_S	539_N	2.134	1.00
155_E	237_T	2.124	1.00
279_D	284_Q	2.121	1.00
77_I	406_F	2.121	1.00
253_V	258_G	2.117	1.00
415_V	480_T	2.099	1.00
301_M	494_L	2.098	1.00
156_E	270_I	2.074	1.00
212_E	218_D	2.068	1.00
108_T	161_W	2.036	1.00
277_W	284_Q	2.035	1.00
322_Q	543_H	2.024	1.00
46_D	411_R	2.018	1.00
231_L	244_K	1.995	1.00
160_K	272_I	1.954	1.00
242_K	266_E	1.954	1.00
497_I	501_I	1.942	1.00
106_D	274_E	1.912	1.00
511_V	557_S	1.910	1.00
471_L	497_I	1.910	1.00
215_K	218_D	1.897	1.00
62_D	65_K	1.880	1.00
235_K	239_A	1.875	1.00
366_N	369_Q	1.867	1.00
304_I	327_T	1.859	1.00
231_L	235_K	1.844	1.00
224_D	434_D	1.842	1.00
109_I	288_T	1.833	1.00
409_A	567_F	1.827	1.00
296_I	339_A	1.826	1.00
271_T	343_E	1.824	1.00
230_K	234_S	1.821	1.00
57_S	580_I	1.795	1.00
278_G	299_L	1.786	1.00
231_L	239_A	1.780	1.00
247_K	251_D	1.778	1.00
263_K	267_N	1.766	1.00
71_I	157_A	1.766	1.00
152_K	270_I	1.761	1.00
178_E	227_K	1.752	1.00
167_K	234_S	1.749	1.00
195_Q	199_S	1.746	1.00
277_W	286_A	1.743	1.00
118_A	267_N	1.735	1.00
75_V	158_L	1.734	1.00
409_A	415_V	1.721	1.00
62_D	66_K	1.710	1.00
360_E	363_Q	1.668	1.00
151_L	232_I	1.668	1.00
156_E	159_D	1.657	1.00
58_E	62_D	1.653	1.00
508_K	512_E	1.653	1.00
479_L	559_S	1.646	1.00
512_E	573_S	1.630	1.00
84_T	181_F	1.624	1.00
479_L	500_H	1.615	1.00
163_T	412_W	1.615	1.00
407_T	480_T	1.611	1.00
250_S	254_Q	1.600	1.00
49_V	77_I	1.596	1.00
508_K	570_V	1.592	1.00
62_D	175_K	1.574	1.00
100_Y	107_T	1.566	1.00
323_L	367_L	1.558	1.00
158_L	169_L	1.542	1.00
77_I	408_V	1.506	1.00
158_L	166_M	1.505	1.00
115_R	268_Y	1.504	1.00
142_G	253_V	1.492	1.00
320_K	503_Y	1.484	1.00
298_L	467_T	1.482	1.00
231_L	245_F	1.472	1.00
313_Y	323_L	1.472	1.00
185_S	216_E	1.468	1.00
63_V	164_R	1.468	1.00
415_V	477_P	1.466	1.00
250_S	261_T	1.463	1.00
95_G	153_G	1.453	1.00
170_I	174_I	1.452	1.00
498_L	502_E	1.451	1.00
156_E	272_I	1.445	1.00
165_S	168_Q	1.444	1.00
119_G	261_T	1.439	1.00
535_L	539_N	1.431	1.00
278_G	303_K	1.430	1.00
116_A	459_N	1.430	1.00
496_T	555_V	1.427	1.00
100_Y	105_K	1.421	1.00
182_P	219_T	1.414	1.00
309_N	312_Q	1.406	1.00
421_T	442_E	1.401	1.00
554_N	575_R	1.397	1.00
202_A	205_D	1.395	1.00
71_I	99_V	1.393	1.00
96_F	291_P	1.391	1.00
174_I	230_K	1.390	1.00
155_E	166_M	1.384	1.00
251_D	255_D	1.370	1.00
537_K	540_G	1.362	1.00
326_E	329_H	1.361	1.00
61_A	65_K	1.360	1.00
119_G	259_S	1.357	1.00
559_S	568_K	1.353	1.00
152_K	237_T	1.349	1.00
322_Q	326_E	1.344	1.00
359_K	362_Q	1.337	1.00
308_F	362_Q	1.335	1.00
63_V	66_K	1.334	1.00
107_T	286_A	1.334	1.00
262_E	266_E	1.320	1.00
141_K	430_I	1.320	1.00
158_L	163_T	1.319	1.00
303_K	306_D	1.314	1.00
253_V	260_M	1.311	1.00
560_I	567_F	1.309	1.00
361_R	364_L	1.303	1.00
248_T	435_Y	1.300	1.00
109_I	289_P	1.299	1.00
63_V	169_L	1.294	1.00
279_D	282_G	1.291	1.00
244_K	247_K	1.291	1.00
526_Y	535_L	1.286	1.00
111_D	273_D	1.280	1.00
285_I	471_L	1.280	1.00
267_N	459_N	1.279	1.00
50_A	556_Q	1.278	1.00
145_V	439_L	1.273	1.00
532_K	536_S	1.270	1.00
499_Y	503_Y	1.268	1.00
563_E	566_T	1.259	1.00
500_H	559_S	1.259	1.00
536_S	540_G	1.254	1.00
152_K	238_D	1.251	1.00
330_L	364_L	1.248	1.00
118_A	459_N	1.241	1.00
95_G	112_S	1.238	1.00
71_I	416_V	1.230	1.00
366_N	370_V	1.217	1.00
495_Q	515_R	1.207	1.00
535_L	545_F	1.201	1.00
561_D	568_K	1.198	1.00
61_A	580_I	1.194	1.00
505_M	513_E	1.193	1.00
66_K	164_R	1.186	1.00
168_Q	171_T	1.185	1.00
108_T	160_K	1.181	1.00
283_Y	478_V	1.181	1.00
59_I	80_A	1.180	1.00
98_M	109_I	1.179	1.00
147_V	260_M	1.172	1.00
110_I	157_A	1.169	1.00
242_K	246_A	1.161	1.00
305_L	494_L	1.161	1.00
321_Y	325_A	1.160	1.00
499_Y	513_E	1.159	1.00
319_E	367_L	1.158	1.00
298_L	494_L	1.158	1.00
473_K	476_K	1.154	1.00
71_I	414_N	1.148	1.00
110_I	270_I	1.148	1.00
449_I	452_G	1.147	1.00
214_L	218_D	1.146	1.00
318_W	541_M	1.145	1.00
201_T	205_D	1.144	1.00
108_T	272_I	1.141	1.00
344_F	460_K	1.138	1.00
283_Y	501_I	1.136	1.00
301_M	327_T	1.134	1.00
99_V	157_A	1.134	1.00
301_M	328_M	1.131	1.00
500_H	507_L	1.127	1.00
308_F	323_L	1.125	1.00
318_W	534_V	1.124	1.00
204_K	208_L	1.123	1.00
69_N	163_T	1.123	1.00
115_R	459_N	1.122	1.00
51_T	60_G	1.118	1.00
156_E	269_D	1.117	1.00
100_Y	472_F	1.117	1.00
41_V	506_E	1.114	1.00
205_D	224_D	1.108	1.00
355_P	359_K	1.102	1.00
263_K	266_E	1.101	1.00
326_E	543_H	1.099	0.99
334_D	361_R	1.094	0.99
110_I	161_W	1.090	0.99
63_V	76_A	1.088	0.99
278_G	355_P	1.086	0.99
472_F	477_P	1.086	0.99
156_E	160_K	1.085	0.99
406_F	418_Y	1.085	0.99
317_S	320_K	1.085	0.99
321_Y	534_V	1.082	0.99
252_T	432_V	1.082	0.99
309_N	313_Y	1.081	0.99
166_M	169_L	1.074	0.99
74_A	416_V	1.074	0.99
478_V	559_S	1.069	0.99
432_V	439_L	1.069	0.99
178_E	223_K	1.069	0.99
56_A	81_L	1.064	0.99
75_V	169_L	1.061	0.99
151_L	237_T	1.060	0.99
62_D	172_P	1.059	0.99
171_T	174_I	1.059	0.99
334_D	357_Y	1.058	0.99
152_K	156_E	1.056	0.99
296_I	349_L	1.054	0.99
228_T	437_V	1.048	0.99
158_L	165_S	1.045	0.99
481_V	496_T	1.044	0.99
118_A	263_K	1.037	0.99
142_G	256_F	1.037	0.99
97_M	153_G	1.035	0.99
75_V	154_L	1.035	0.99
166_M	170_I	1.035	0.99
284_Q	472_F	1.030	0.99
535_L	547_T	1.028	0.99
248_T	251_D	1.026	0.99
314_D	317_S	1.024	0.99
377_G	380_W	1.021	0.99
227_K	230_K	1.021	0.99
43_V	568_K	1.018	0.99
188_A	215_K	1.013	0.99
507_L	570_V	1.013	0.99
457_Q	460_K	1.012	0.99
405_H	417_S	1.010	0.99
63_V	168_Q	1.009	0.99
111_D	291_P	1.006	0.99
299_L	353_L	1.001	0.99
480_T	558_I	1.001	0.99
120_A	124_M	0.997	0.99
149_G	268_Y	0.996	0.99
477_P	480_T	0.995	0.99
63_V	172_P	0.993	0.99
285_I	302_L	0.993	0.99
374_P	377_G	0.992	0.99
47_G	64_L	0.988	0.99
244_K	248_T	0.983	0.99
260_M	265_L	0.983	0.99
82_N	225_L	0.982	0.99
569_G	579_A	0.980	0.99
48_M	567_F	0.980	0.99
300_Q	334_D	0.980	0.99
122_P	457_Q	0.979	0.99
122_P	455_E	0.978	0.99
345_V	348_P	0.978	0.99
304_I	307_H	0.976	0.99
79_F	151_L	0.975	0.99
445_D	487_A	0.973	0.99
320_K	324_L	0.969	0.99
113_R	291_P	0.968	0.99
301_M	331_S	0.966	0.99
409_A	558_I	0.965	0.99
310_L	313_Y	0.965	0.99
50_A	571_A	0.963	0.99
248_T	434_D	0.962	0.99
422_I	438_I	0.962	0.99
78_Q	420_T	0.960	0.99
534_V	537_K	0.959	0.99
58_E	65_K	0.959	0.99
103_K	106_D	0.959	0.99
53_H	84_T	0.957	0.99
212_E	215_K	0.954	0.99
134_P	138_R	0.948	0.99
245_F	248_T	0.948	0.99
415_V	470_I	0.947	0.98
48_M	558_I	0.943	0.98
55_L	59_I	0.941	0.98
52_A	85_E	0.941	0.98
405_H	482_G	0.939	0.98
483_S	492_S	0.937	0.98
476_K	560_I	0.937	0.98
454_N	460_K	0.935	0.98
59_I	173_S	0.931	0.98
451_G	455_E	0.931	0.98
152_K	155_E	0.930	0.98
145_V	430_I	0.927	0.98
488_T	492_S	0.926	0.98
227_K	234_S	0.925	0.98
228_T	245_F	0.924	0.98
188_A	192_S	0.920	0.98
192_S	215_K	0.920	0.98
283_Y	473_K	0.919	0.98
330_L	361_R	0.917	0.98
281_Q	308_F	0.916	0.98
310_L	498_L	0.915	0.98
187_L	191_I	0.914	0.98
246_A	265_L	0.913	0.98
74_A	408_V	0.913	0.98
473_K	478_V	0.913	0.98
183_I	188_A	0.912	0.98
302_L	497_I	0.912	0.98
222_Q	437_V	0.910	0.98
59_I	76_A	0.907	0.98
178_E	226_A	0.906	0.98
432_V	435_Y	0.905	0.98
511_V	555_V	0.905	0.98
321_Y	530_V	0.903	0.98
158_L	164_R	0.902	0.98
126_L	450_P	0.898	0.98
304_I	362_Q	0.898	0.98
203_A	438_I	0.898	0.98
304_I	365_I	0.894	0.98
185_S	189_E	0.893	0.98
252_T	255_D	0.892	0.98
227_K	231_L	0.892	0.98
526_Y	530_V	0.892	0.98
447_D	450_P	0.892	0.98
112_S	418_Y	0.887	0.98
526_Y	545_F	0.884	0.98
80_A	84_T	0.881	0.98
249_L	439_L	0.881	0.98
531_P	535_L	0.876	0.98
320_K	498_L	0.875	0.97
317_S	503_Y	0.873	0.97
164_R	168_Q	0.873	0.97
44_G	48_M	0.871	0.97
165_S	169_L	0.869	0.97
41_V	568_K	0.862	0.97
404_T	420_T	0.860	0.97
206_V	222_Q	0.859	0.97
50_A	558_I	0.855	0.97
110_I	156_E	0.852	0.97
319_E	323_L	0.851	0.97
246_A	262_E	0.851	0.97
279_D	306_D	0.847	0.97
471_L	479_L	0.847	0.97
410_D	414_N	0.846	0.97
340_G	462_P	0.844	0.97
45_K	566_T	0.844	0.97
208_L	214_L	0.843	0.97
248_T	433_P	0.842	0.97
250_S	253_V	0.842	0.97
355_P	358_I	0.840	0.97
120_A	259_S	0.840	0.97
225_L	229_F	0.839	0.97
82_N	229_F	0.837	0.97
145_V	428_T	0.836	0.97
539_N	544_K	0.835	0.97
447_D	455_E	0.832	0.97
116_A	120_A	0.828	0.96
252_T	430_I	0.826	0.96
83_V	177_A	0.825	0.96
164_R	169_L	0.824	0.96
366_N	371_N	0.821	0.96
142_G	252_T	0.818	0.96
409_A	560_I	0.818	0.96
89_S	420_T	0.818	0.96
526_Y	547_T	0.817	0.96
281_Q	501_I	0.816	0.96
344_F	457_Q	0.816	0.96
481_V	557_S	0.815	0.96
469_T	481_V	0.815	0.96
278_G	358_I	0.814	0.96
525_R	546_G	0.813	0.96
354_H	358_I	0.812	0.96
209_P	212_E	0.808	0.96
222_Q	225_L	0.807	0.96
83_V	173_S	0.807	0.96
115_R	343_E	0.805	0.96
491_S	517_Y	0.803	0.96
252_T	256_F	0.803	0.96
101_D	108_T	0.801	0.96
143_T	259_S	0.799	0.96
124_M	128_E	0.797	0.96
531_P	534_V	0.797	0.96
275_P	286_A	0.795	0.96
183_I	220_L	0.795	0.96
505_M	509_A	0.793	0.96
245_F	437_V	0.791	0.95
351_G	379_P	0.790	0.95
253_V	439_L	0.789	0.95
120_A	125_F	0.789	0.95
95_G	418_Y	0.788	0.95
423_E	445_D	0.783	0.95
232_I	237_T	0.783	0.95
114_E	442_E	0.780	0.95
328_M	494_L	0.776	0.95
228_T	435_Y	0.772	0.95
279_D	355_P	0.768	0.95
124_M	259_S	0.765	0.95
201_T	204_K	0.764	0.95
183_I	214_L	0.762	0.94
115_R	271_T	0.760	0.94
276_I	287_T	0.758	0.94
123_D	126_L	0.755	0.94
59_I	176_L	0.755	0.94
315_V	505_M	0.754	0.94
110_I	160_K	0.752	0.94
245_F	249_L	0.752	0.94
357_Y	361_R	0.749	0.94
281_Q	306_D	0.749	0.94
298_L	493_V	0.747	0.94
203_A	431_M	0.747	0.94
183_I	187_L	0.746	0.94
76_A	169_L	0.746	0.94
127_D	130_G	0.745	0.94
287_T	493_V	0.742	0.94
324_L	516_I	0.742	0.94
49_V	64_L	0.740	0.94
304_I	358_I	0.740	0.94
305_L	310_L	0.739	0.94
122_P	126_L	0.738	0.93
92_G	437_V	0.738	0.93
174_I	178_E	0.737	0.93
256_F	430_I	0.737	0.93
539_N	547_T	0.735	0.93
126_L	130_G	0.734	0.93
321_Y	516_I	0.734	0.93
55_L	84_T	0.733	0.93
55_L	182_P	0.733	0.93
287_T	467_T	0.732	0.93
479_L	507_L	0.732	0.93
304_I	361_R	0.732	0.93
83_V	225_L	0.728	0.93
273_D	289_P	0.728	0.93
146_G	443_L	0.727	0.93
64_L	408_V	0.726	0.93
253_V	256_F	0.726	0.93
423_E	444_T	0.724	0.93
148_P	439_L	0.724	0.93
228_T	231_L	0.722	0.93
239_A	244_K	0.722	0.93
287_T	469_T	0.721	0.93
96_F	292_S	0.720	0.93
78_Q	406_F	0.720	0.93
478_V	500_H	0.720	0.93
199_S	204_K	0.718	0.93
77_I	80_A	0.715	0.92
359_K	363_Q	0.714	0.92
527_E	574_S	0.712	0.92
471_L	501_I	0.709	0.92
59_I	63_V	0.709	0.92
57_S	77_I	0.709	0.92
57_S	578_A	0.708	0.92
311_S	504_G	0.708	0.92
470_I	477_P	0.707	0.92
44_G	47_G	0.705	0.92
284_Q	475_D	0.705	0.92
184_D	576_N	0.704	0.92
60_G	408_V	0.704	0.92
100_Y	103_K	0.702	0.92
558_I	567_F	0.702	0.92
322_Q	365_I	0.701	0.92
55_L	176_L	0.698	0.91
223_K	227_K	0.698	0.91
98_M	470_I	0.698	0.91
424_Q	441_N	0.698	0.91
209_P	214_L	0.696	0.91
481_V	497_I	0.695	0.91
99_V	416_V	0.695	0.91
85_E	554_N	0.694	0.91
449_I	455_E	0.694	0.91
319_E	537_K	0.694	0.91
287_T	298_L	0.693	0.91
99_V	414_N	0.692	0.91
238_D	266_E	0.692	0.91
57_S	61_A	0.692	0.91
328_M	491_S	0.691	0.91
94_G	114_E	0.690	0.91
283_Y	471_L	0.689	0.91
91_I	151_L	0.689	0.91
432_V	437_V	0.688	0.91
91_I	232_I	0.688	0.91
125_F	141_K	0.688	0.91
96_F	464_S	0.686	0.91
132_A	135_F	0.686	0.91
326_E	365_I	0.685	0.91
248_T	432_V	0.684	0.91
138_R	448_A	0.680	0.90
55_L	58_E	0.680	0.90
53_H	184_D	0.679	0.90
58_E	61_A	0.676	0.90
191_I	208_L	0.676	0.90
322_Q	329_H	0.675	0.90
78_Q	418_Y	0.675	0.90
507_L	568_K	0.674	0.90
278_G	306_D	0.673	0.90
58_E	580_I	0.672	0.90
120_A	456_V	0.672	0.90
107_T	472_F	0.671	0.90
177_A	226_A	0.671	0.90
324_L	498_L	0.670	0.90
102_G	105_K	0.670	0.90
119_G	254_Q	0.669	0.90
288_T	292_S	0.668	0.90
366_N	541_M	0.667	0.89
254_Q	261_T	0.666	0.89
150_T	420_T	0.664	0.89
367_L	541_M	0.662	0.89
532_K	547_T	0.661	0.89
157_A	416_V	0.661	0.89
71_I	101_D	0.661	0.89
314_D	320_K	0.661	0.89
75_V	170_I	0.661	0.89
224_D	227_K	0.656	0.89
285_I	469_T	0.655	0.89
47_G	61_A	0.654	0.89
155_E	236_G	0.653	0.88
409_A	480_T	0.653	0.88
297_F	335_R	0.653	0.88
284_Q	473_K	0.652	0.88
57_S	579_A	0.651	0.88
351_G	354_H	0.649	0.88
311_S	314_D	0.648	0.88
249_L	265_L	0.648	0.88
206_V	431_M	0.647	0.88
116_A	446_F	0.647	0.88
191_I	214_L	0.646	0.88
276_I	339_A	0.646	0.88
308_F	365_I	0.644	0.88
498_L	503_Y	0.643	0.88
330_L	371_N	0.643	0.88
240_F	246_A	0.643	0.88
500_H	504_G	0.642	0.88
125_F	144_A	0.641	0.88
124_M	127_D	0.641	0.88
192_S	195_Q	0.641	0.88
114_E	146_G	0.639	0.87
362_Q	365_I	0.638	0.87
301_M	491_S	0.637	0.87
142_G	430_I	0.636	0.87
108_T	274_E	0.636	0.87
155_E	158_L	0.636	0.87
79_F	166_M	0.635	0.87
141_K	428_T	0.633	0.87
314_D	503_Y	0.631	0.87
152_K	268_Y	0.631	0.87
556_Q	571_A	0.630	0.87
171_T	233_R	0.629	0.87
340_G	345_V	0.629	0.87
340_G	453_A	0.628	0.86
140_T	143_T	0.626	0.86
102_G	412_W	0.625	0.86
123_D	127_D	0.625	0.86
371_N	376_A	0.625	0.86
407_T	558_I	0.625	0.86
100_Y	477_P	0.624	0.86
315_V	320_K	0.624	0.86
141_K	144_A	0.623	0.86
195_Q	208_L	0.623	0.86
118_A	261_T	0.622	0.86
195_Q	212_E	0.620	0.86
448_A	456_V	0.620	0.86
75_V	162_G	0.618	0.86
202_A	252_T	0.617	0.86
500_H	510_A	0.617	0.86
300_Q	357_Y	0.613	0.85
181_F	220_L	0.613	0.85
60_G	80_A	0.613	0.85
511_V	570_V	0.612	0.85
69_N	412_W	0.611	0.85
79_F	154_L	0.610	0.85
43_V	566_T	0.609	0.85
507_L	511_V	0.609	0.85
335_R	339_A	0.608	0.85
173_S	177_A	0.608	0.85
114_E	465_S	0.608	0.85
297_F	339_A	0.607	0.85
533_D	536_S	0.607	0.85
113_R	445_D	0.606	0.85
322_Q	541_M	0.606	0.85
59_I	62_D	0.605	0.84
322_Q	367_L	0.605	0.84
316_R	320_K	0.605	0.84
351_G	380_W	0.605	0.84
467_T	493_V	0.604	0.84
297_F	331_S	0.604	0.84
431_M	438_I	0.603	0.84
235_K	244_K	0.603	0.84
307_H	355_P	0.603	0.84
492_S	555_V	0.602	0.84
96_F	113_R	0.601	0.84
208_L	213_P	0.601	0.84
561_D	566_T	0.600	0.84
273_D	343_E	0.600	0.84
190_A	425_L	0.600	0.84
440_N	443_L	0.599	0.84
82_N	90_G	0.599	0.84
305_L	323_L	0.599	0.84
488_T	552_I	0.598	0.84
60_G	76_A	0.597	0.84
356_D	360_E	0.596	0.84
99_V	108_T	0.596	0.84
300_Q	304_I	0.596	0.84
360_E	364_L	0.595	0.83
254_Q	260_M	0.595	0.83
313_Y	320_K	0.594	0.83
442_E	465_S	0.594	0.83
80_A	173_S	0.593	0.83
117_P	120_A	0.592	0.83
495_Q	499_Y	0.592	0.83
170_I	233_R	0.592	0.83
134_P	137_E	0.591	0.83
196_E	199_S	0.591	0.83
47_G	411_R	0.591	0.83
97_M	112_S	0.590	0.83
115_R	118_A	0.589	0.83
150_T	421_T	0.589	0.83
481_V	493_V	0.587	0.83
405_H	419_T	0.586	0.83
163_T	169_L	0.585	0.82
78_Q	150_T	0.584	0.82
101_D	414_N	0.583	0.82
469_T	497_I	0.582	0.82
82_N	89_S	0.582	0.82
187_L	220_L	0.581	0.82
81_L	404_T	0.579	0.82
202_A	433_P	0.579	0.82
523_S	544_K	0.579	0.82
78_Q	154_L	0.579	0.82
85_E	88_M	0.578	0.82
111_D	271_T	0.577	0.82
276_I	299_L	0.575	0.81
219_T	566_T	0.575	0.81
76_A	173_S	0.574	0.81
353_L	358_I	0.573	0.81
52_A	404_T	0.573	0.81
81_L	406_F	0.572	0.81
113_R	464_S	0.571	0.81
530_V	535_L	0.571	0.81
571_A	575_R	0.571	0.81
419_T	489_I	0.570	0.81
415_V	560_I	0.569	0.81
70_A	416_V	0.569	0.81
305_L	324_L	0.568	0.81
250_S	260_M	0.567	0.80
239_A	242_K	0.566	0.80
144_A	428_T	0.566	0.80
492_S	553_G	0.565	0.80
332_Y	490_I	0.565	0.80
488_T	517_Y	0.564	0.80
301_M	490_I	0.563	0.80
71_I	97_M	0.563	0.80
115_R	461_R	0.562	0.80
327_T	331_S	0.561	0.80
324_L	327_T	0.560	0.80
251_D	434_D	0.558	0.79
253_V	265_L	0.557	0.79
488_T	491_S	0.556	0.79
477_P	560_I	0.555	0.79
140_T	197_K	0.554	0.79
95_G	150_T	0.554	0.79
528_D	547_T	0.554	0.79
94_G	113_R	0.553	0.79
88_M	422_I	0.551	0.79
98_M	275_P	0.550	0.78
69_N	164_R	0.550	0.78
280_Y	310_L	0.549	0.78
516_I	530_V	0.549	0.78
98_M	288_T	0.549	0.78
408_V	416_V	0.549	0.78
133_I	137_E	0.548	0.78
445_D	465_S	0.547	0.78
327_T	365_I	0.547	0.78
571_A	579_A	0.546	0.78
419_T	464_S	0.546	0.78
101_D	106_D	0.545	0.78
409_A	477_P	0.545	0.78
63_V	77_I	0.544	0.78
518_T	524_Y	0.543	0.78
41_V	570_V	0.543	0.78
500_H	557_S	0.543	0.78
224_D	431_M	0.542	0.77
207_F	222_Q	0.542	0.77
236_G	239_A	0.541	0.77
483_S	553_G	0.540	0.77
407_T	417_S	0.540	0.77
273_D	288_T	0.540	0.77
259_S	456_V	0.540	0.77
98_M	107_T	0.540	0.77
113_R	442_E	0.539	0.77
59_I	172_P	0.538	0.77
216_E	219_T	0.538	0.77
249_L	437_V	0.538	0.77
189_E	193_D	0.538	0.77
452_G	455_E	0.536	0.77
94_G	464_S	0.534	0.76
97_M	416_V	0.534	0.76
310_L	323_L	0.533	0.76
478_V	560_I	0.533	0.76
539_N	545_F	0.533	0.76
133_I	138_R	0.533	0.76
226_A	230_K	0.532	0.76
519_N	522_S	0.531	0.76
85_E	90_G	0.531	0.76
188_A	213_P	0.531	0.76
179_K	230_K	0.529	0.76
84_T	141_K	0.528	0.76
442_E	489_I	0.527	0.75
195_Q	213_P	0.527	0.75
46_D	65_K	0.525	0.75
152_K	242_K	0.525	0.75
145_V	253_V	0.523	0.75
445_D	464_S	0.522	0.75
310_L	503_Y	0.521	0.75
287_T	490_I	0.521	0.75
324_L	328_M	0.521	0.75
87_M	187_L	0.520	0.74
142_G	145_V	0.520	0.74
114_E	445_D	0.519	0.74
300_Q	358_I	0.518	0.74
196_E	200_R	0.518	0.74
221_I	224_D	0.518	0.74
91_I	437_V	0.518	0.74
109_I	273_D	0.517	0.74
94_G	489_I	0.517	0.74
292_S	466_M	0.516	0.74
298_L	469_T	0.516	0.74
228_T	433_P	0.515	0.74
492_S	552_I	0.515	0.74
443_L	446_F	0.514	0.74
374_P	524_Y	0.514	0.74
116_A	457_Q	0.513	0.73
94_G	466_M	0.513	0.73
315_V	503_Y	0.513	0.73
484_P	575_R	0.512	0.73
161_W	272_I	0.512	0.73
155_E	169_L	0.511	0.73
361_R	377_G	0.511	0.73
117_P	258_G	0.510	0.73
230_K	233_R	0.510	0.73
146_G	440_N	0.510	0.73
45_K	219_T	0.510	0.73
531_P	536_S	0.509	0.73
105_K	476_K	0.509	0.73
328_M	516_I	0.508	0.73
153_G	270_I	0.508	0.73
114_E	423_E	0.507	0.73
507_L	559_S	0.506	0.72
479_L	557_S	0.506	0.72
517_Y	520_S	0.505	0.72
184_D	569_G	0.505	0.72
121_T	124_M	0.504	0.72
75_V	82_N	0.503	0.72
364_L	377_G	0.503	0.72
103_K	107_T	0.502	0.72
87_M	190_A	0.501	0.72
285_I	497_I	0.501	0.72
454_N	463_L	0.500	0.72
93_G	440_N	0.500	0.72
252_T	435_Y	0.500	0.72
465_S	489_I	0.500	0.72
297_F	336_A	0.500	0.72

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2e0wA	1	0.8484	100	0.085	Contact Map
2nlzA	4	0.9012	100	0.098	Contact Map
2i3oA	2	0.862	100	0.119	Contact Map
3whrA	1	0.6116	100	0.361	Contact Map
2dg5A	1	0.5911	100	0.419	Contact Map
2qmcA	1	0.586	100	0.424	Contact Map
4gdxA	1	0.569	100	0.427	Contact Map
3g9kL	1	0.4821	100	0.466	Contact Map
3whrB	1	0.3118	100	0.66	Contact Map
4gdxB	1	0.3032	100	0.673	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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