GREMLIN Database
ASNB - Asparagine synthetase [glutamine-hydrolyzing] 1
UniProt: P54420 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 632 (605)
Sequences: 3328 (2771)
Seq/√Len: 112.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
37_S62_G4.2441.00
175_E198_A4.0691.00
109_T113_Y3.8441.00
244_A508_V3.7431.00
27_N49_G3.7201.00
284_K311_E3.5791.00
261_S273_V3.5761.00
271_F531_A3.3391.00
23_I47_G3.3061.00
302_K314_S3.2151.00
89_E120_K3.1901.00
139_G149_L3.1381.00
95_Y112_H3.1061.00
246_Y278_E3.0721.00
177_D194_S3.0411.00
66_S73_W3.0061.00
136_V212_R2.9691.00
116_E119_S2.9671.00
146_I498_V2.9671.00
74_I103_T2.9141.00
144_F506_F2.8751.00
93_K112_H2.7901.00
245_I275_V2.7311.00
136_V210_T2.7081.00
242_R533_G2.6841.00
128_L139_G2.6271.00
529_K532_E2.5891.00
165_K334_D2.5471.00
113_Y120_K2.5221.00
67_Y111_R2.4921.00
303_E538_H2.4811.00
234_E529_K2.4691.00
109_T117_A2.4581.00
159_Y170_A2.4011.00
285_T310_I2.3741.00
61_G101_S2.3601.00
38_D51_R2.3451.00
251_V504_V2.3351.00
365_A500_F2.2931.00
489_T496_L2.2911.00
204_E207_S2.2861.00
67_Y71_T2.2711.00
287_S301_A2.2651.00
143_P503_K2.2511.00
203_V209_F2.2511.00
204_E219_F2.2041.00
302_K306_A2.1881.00
158_V211_I2.1721.00
117_A121_L2.1671.00
260_G356_V2.1561.00
146_I252_H2.1471.00
139_G209_F2.1461.00
6_G160_F2.1341.00
84_I254_R2.1021.00
118_A208_Q2.0781.00
208_Q220_K2.0681.00
247_D504_V2.0451.00
351_E354_K2.0381.00
71_T133_N2.0341.00
95_Y108_A2.0041.00
232_T237_L2.0011.00
110_Y129_I1.9941.00
233_E236_K1.9841.00
504_V507_D1.9781.00
606_M610_S1.9721.00
234_E516_L1.9631.00
72_Y107_L1.9591.00
240_E244_A1.9571.00
122_R504_V1.9521.00
300_V542_R1.9511.00
202_K335_D1.9441.00
43_D132_K1.9351.00
125_F140_A1.9311.00
503_K507_D1.9281.00
32_H163_E1.9251.00
537_E541_N1.9211.00
118_A140_A1.9181.00
130_W137_L1.9121.00
369_F509_A1.9061.00
270_S304_T1.9041.00
177_D201_K1.9021.00
122_R503_K1.8941.00
519_K525_Y1.8881.00
242_R530_A1.8851.00
67_Y108_A1.8761.00
284_K313_I1.8751.00
331_W611_I1.8741.00
350_K354_K1.8351.00
587_D595_N1.8141.00
240_E243_D1.8071.00
242_R534_I1.7981.00
573_D606_M1.7811.00
241_V369_F1.7751.00
177_D198_A1.7691.00
463_S514_D1.7511.00
151_Y201_K1.7491.00
353_K357_T1.7461.00
115_E220_K1.7441.00
237_L512_I1.7421.00
525_Y529_K1.7371.00
253_M276_A1.7341.00
56_I83_Y1.7291.00
69_D111_R1.7241.00
375_Y472_D1.7191.00
234_E525_Y1.7181.00
248_S252_H1.7181.00
241_V508_V1.7161.00
83_Y105_V1.6981.00
363_E484_K1.6881.00
5_V26_M1.6871.00
73_W132_K1.6851.00
159_Y167_L1.6771.00
247_D251_V1.6731.00
207_S221_T1.6671.00
88_E91_E1.6491.00
118_A138_Y1.6481.00
109_T121_L1.6461.00
285_T312_N1.6461.00
388_P392_K1.6391.00
122_R247_D1.6301.00
328_K350_K1.6101.00
532_E541_N1.6081.00
106_L121_L1.5981.00
273_V310_I1.5911.00
76_F80_I1.5891.00
207_S219_F1.5871.00
240_E508_V1.5801.00
5_V27_N1.5701.00
108_A111_R1.5691.00
532_E537_E1.5631.00
301_A305_A1.5581.00
588_H594_D1.5421.00
223_F507_D1.5421.00
117_A138_Y1.5401.00
135_H213_P1.5361.00
271_F530_A1.5291.00
349_A489_T1.5281.00
83_Y254_R1.5241.00
533_G537_E1.5121.00
110_Y117_A1.5101.00
154_I157_Q1.5071.00
130_W135_H1.5011.00
5_V49_G1.4961.00
80_I106_L1.4931.00
209_F217_I1.4871.00
106_L117_A1.4761.00
115_E210_T1.4761.00
320_E324_N1.4731.00
89_E113_Y1.4721.00
37_S50_F1.4721.00
246_Y279_F1.4591.00
508_V512_I1.4441.00
122_R502_D1.4411.00
74_I107_L1.4371.00
127_F140_A1.4361.00
161_A166_S1.4361.00
27_N51_R1.4241.00
115_E138_Y1.4211.00
61_G99_T1.4201.00
68_E108_A1.4141.00
59_E99_T1.4131.00
252_H498_V1.4051.00
244_A505_V1.4041.00
55_I358_V1.4021.00
246_Y275_V1.3981.00
23_I49_G1.3921.00
245_I500_F1.3901.00
71_T134_D1.3881.00
239_K533_G1.3881.00
273_V285_T1.3851.00
24_K28_Q1.3841.00
83_Y100_D1.3831.00
234_E519_K1.3741.00
138_Y208_Q1.3731.00
261_S285_T1.3731.00
48_F160_F1.3681.00
76_F103_T1.3541.00
138_Y210_T1.3521.00
6_G128_L1.3501.00
122_R251_V1.3471.00
30_I166_S1.3401.00
348_V352_A1.3401.00
93_K113_Y1.3341.00
463_S466_N1.3331.00
251_V254_R1.3331.00
238_V530_A1.3321.00
65_L107_L1.3281.00
122_R252_H1.3251.00
332_H491_A1.3030.99
68_E111_R1.3030.99
74_I127_F1.3020.99
110_Y138_Y1.2970.99
206_G223_F1.2950.99
241_V505_V1.2870.99
28_Q51_R1.2860.99
192_E479_G1.2840.99
238_V529_K1.2820.99
106_L127_F1.2820.99
72_Y111_R1.2810.99
42_H47_G1.2660.99
232_T236_K1.2650.99
370_G518_T1.2610.99
352_A359_A1.2610.99
234_E238_V1.2600.99
22_L171_Q1.2570.99
237_L516_L1.2540.99
74_I129_I1.2500.99
39_G62_G1.2410.99
30_I51_R1.2410.99
27_N40_Y1.2360.99
18_D47_G1.2350.99
276_A283_L1.2340.99
71_T111_R1.2290.99
270_S300_V1.2280.99
140_A208_Q1.2260.99
31_V51_R1.2240.99
333_F488_M1.2200.99
24_K38_D1.2200.99
89_E93_K1.2130.99
240_E511_K1.2100.99
466_N517_K1.2100.99
171_Q174_I1.2080.99
128_L160_F1.2030.99
564_R586_E1.1950.99
530_A533_G1.1920.99
126_A149_L1.1860.99
127_F138_Y1.1850.99
272_I500_F1.1810.99
275_V534_I1.1770.99
363_E485_A1.1710.99
286_F355_H1.1590.99
185_M605_F1.1570.99
583_Q587_D1.1560.99
124_M252_H1.1560.99
291_E318_S1.1560.99
289_G316_V1.1540.99
273_V308_L1.1540.99
560_N564_R1.1500.99
56_I254_R1.1460.99
24_K40_Y1.1440.99
183_Q194_S1.1410.99
181_L605_F1.1390.99
224_K474_H1.1380.99
277_K308_L1.1380.99
83_Y87_R1.1350.99
110_Y131_N1.1350.99
168_M174_I1.1320.99
74_I106_L1.1300.99
8_F46_V1.1290.99
6_G139_G1.1270.99
244_A504_V1.1210.98
117_A127_F1.1190.98
72_Y110_Y1.1170.98
582_L586_E1.1140.98
153_T201_K1.1080.98
370_G469_Q1.1050.98
274_S308_L1.1020.98
500_F527_L1.0980.98
289_G298_V1.0960.98
68_E95_Y1.0890.98
71_T132_K1.0890.98
544_K547_F1.0880.98
29_M169_V1.0830.98
242_R246_Y1.0790.98
300_V304_T1.0790.98
20_E24_K1.0780.98
26_M170_A1.0780.98
505_V509_A1.0770.98
247_D250_N1.0760.98
175_E199_H1.0750.98
72_Y133_N1.0740.98
67_Y72_Y1.0710.98
241_V509_A1.0710.98
248_S502_D1.0710.98
560_N589_C1.0700.98
37_S54_S1.0690.98
550_P554_W1.0670.98
298_V314_S1.0650.98
150_Y487_K1.0610.98
339_D484_K1.0600.98
321_E324_N1.0560.98
577_H580_Y1.0550.98
124_M146_I1.0540.98
255_S259_V1.0490.98
272_I360_L1.0480.98
65_L103_T1.0460.98
485_A496_L1.0450.98
48_F75_I1.0430.98
27_N38_D1.0410.97
261_S276_A1.0330.97
513_P516_L1.0330.97
129_I138_Y1.0300.97
2_C77_N1.0300.97
87_R97_F1.0290.97
522_T528_R1.0280.97
4_F50_F1.0260.97
232_T240_E1.0230.97
85_E254_R1.0190.97
241_V245_I1.0160.97
244_A247_D1.0130.97
139_G160_F1.0120.97
224_K470_Y1.0100.97
341_A484_K1.0080.97
118_A127_F1.0070.97
259_V358_V1.0000.97
30_I161_A0.9990.97
575_Y609_H0.9980.97
3_G33_R0.9940.97
108_A112_H0.9940.97
97_F105_V0.9930.97
361_S496_L0.9910.97
153_T158_V0.9870.97
22_L170_A0.9840.96
8_F137_L0.9840.96
66_S70_E0.9810.96
110_Y115_E0.9800.96
177_D180_A0.9790.96
270_S535_V0.9780.96
574_A606_M0.9750.96
41_F73_W0.9740.96
437_Q440_K0.9700.96
94_G97_F0.9690.96
72_Y134_D0.9690.96
124_M147_K0.9660.96
325_E347_F0.9650.96
291_E316_V0.9560.96
144_F473_I0.9530.96
234_E237_L0.9500.96
167_L200_V0.9420.95
56_I255_S0.9410.95
576_I581_V0.9410.95
67_Y70_E0.9300.95
203_V219_F0.9290.95
303_E306_A0.9290.95
91_E94_G0.9290.95
250_N279_F0.9280.95
282_S311_E0.9270.95
298_V316_V0.9260.95
345_L485_A0.9230.95
183_Q191_P0.9230.95
260_G352_A0.9210.95
588_H595_N0.9170.95
221_T224_K0.9140.95
556_K588_H0.9100.95
564_R582_L0.9100.95
262_F352_A0.9080.94
81_Y124_M0.9080.94
84_I100_D0.9050.94
131_N134_D0.9040.94
72_Y108_A0.9020.94
31_V38_D0.9020.94
344_P484_K0.9020.94
552_R556_K0.9000.94
27_N30_I0.8980.94
164_R195_T0.8980.94
565_N568_Q0.8980.94
242_R275_V0.8980.94
28_Q38_D0.8970.94
245_I271_F0.8930.94
67_Y73_W0.8930.94
245_I531_A0.8930.94
257_V358_V0.8910.94
4_F75_I0.8910.94
333_F337_L0.8890.94
345_L488_M0.8890.94
334_D487_K0.8880.94
9_N18_D0.8880.94
67_Y95_Y0.8850.94
128_L209_F0.8840.94
238_V242_R0.8830.94
58_V256_D0.8830.94
106_L118_A0.8830.94
82_N85_E0.8770.93
90_L113_Y0.8760.93
7_V159_Y0.8750.93
276_A360_L0.8730.93
70_E98_N0.8730.93
368_L509_A0.8730.93
23_I27_N0.8730.93
206_G222_Y0.8710.93
522_T541_N0.8710.93
241_V527_L0.8690.93
151_Y158_V0.8670.93
238_V533_G0.8660.93
37_S60_N0.8660.93
259_V357_T0.8650.93
71_T108_A0.8650.93
127_F139_G0.8650.93
31_V493_S0.8550.93
115_E136_V0.8540.92
585_L589_C0.8520.92
239_K243_D0.8510.92
358_V497_R0.8500.92
341_A363_E0.8480.92
352_A356_V0.8470.92
363_E481_I0.8450.92
486_D490_M0.8450.92
483_L487_K0.8440.92
296_S299_D0.8440.92
26_M29_M0.8440.92
45_H135_H0.8430.92
164_R197_D0.8370.92
588_H599_I0.8360.92
304_T539_V0.8350.92
37_S61_G0.8350.92
439_L442_Y0.8320.91
246_Y534_I0.8310.91
337_L363_E0.8310.91
149_L203_V0.8280.91
587_D592_K0.8270.91
23_I40_Y0.8270.91
7_V18_D0.8260.91
165_K331_W0.8250.91
587_D593_A0.8250.91
278_E534_I0.8250.91
109_T120_K0.8240.91
578_K582_L0.8230.91
113_Y117_A0.8160.91
286_F313_I0.8080.90
158_V203_V0.8070.90
580_Y583_Q0.8060.90
5_V30_I0.8050.90
39_G51_R0.8030.90
115_E208_Q0.8010.90
164_R200_V0.8010.90
265_G287_S0.7990.90
565_N569_E0.7970.90
535_V540_L0.7960.90
333_F342_A0.7940.89
95_Y111_R0.7920.89
528_R541_N0.7920.89
346_Y491_A0.7900.89
345_L363_E0.7900.89
442_Y446_L0.7900.89
275_V505_V0.7900.89
56_I101_S0.7880.89
237_L508_V0.7870.89
27_N31_V0.7860.89
339_D345_L0.7850.89
134_D212_R0.7840.89
552_R596_S0.7820.89
139_G158_V0.7780.89
39_G61_G0.7780.89
211_I217_I0.7770.88
252_H502_D0.7770.88
564_R585_L0.7760.88
234_E526_L0.7750.88
338_A601_T0.7740.88
586_E590_A0.7730.88
337_L341_A0.7720.88
437_Q442_Y0.7710.88
508_V511_K0.7700.88
128_L137_L0.7700.88
212_R215_G0.7690.88
262_F349_A0.7670.88
179_E194_S0.7660.88
237_L513_P0.7660.88
571_Q610_S0.7640.88
321_E350_K0.7640.88
249_V276_A0.7620.87
257_V357_T0.7620.87
318_S321_E0.7620.87
367_E372_Y0.7600.87
476_W481_I0.7590.87
68_E71_T0.7540.87
88_E92_A0.7530.87
143_P223_F0.7530.87
109_T112_H0.7530.87
245_I527_L0.7520.87
84_I105_V0.7520.87
241_V530_A0.7520.87
313_I355_H0.7520.87
144_F500_F0.7510.87
5_V161_A0.7510.87
433_S436_K0.7490.87
545_L548_P0.7490.87
83_Y97_F0.7470.86
7_V19_Q0.7470.86
29_M166_S0.7460.86
606_M609_H0.7460.86
531_A534_I0.7450.86
286_F356_V0.7450.86
82_N86_L0.7420.86
7_V170_A0.7400.86
346_Y492_N0.7380.86
523_T528_R0.7380.86
152_T167_L0.7370.86
36_D357_T0.7370.86
359_A494_L0.7370.86
552_R594_D0.7360.86
9_N12_P0.7360.86
91_E100_D0.7340.85
442_Y445_N0.7310.85
287_S298_V0.7310.85
144_F223_F0.7300.85
157_Q170_A0.7290.85
60_N99_T0.7290.85
274_S534_I0.7290.85
81_Y147_K0.7270.85
85_E251_V0.7270.85
28_Q31_V0.7230.85
21_E24_K0.7210.84
77_N372_Y0.7210.84
275_V279_F0.7190.84
9_N157_Q0.7190.84
563_V585_L0.7180.84
466_N514_D0.7180.84
56_I84_I0.7150.84
289_G301_A0.7140.84
430_F434_V0.7140.84
374_I377_E0.7120.84
562_W565_N0.7120.84
566_I607_I0.7110.84
148_P162_S0.7090.83
232_T512_I0.7070.83
37_S75_I0.7070.83
595_N598_K0.7060.83
433_S437_Q0.7060.83
531_A535_V0.7060.83
364_G501_L0.7050.83
258_P357_T0.7050.83
233_E237_L0.7050.83
270_S542_R0.7040.83
22_L25_Q0.7040.83
480_D546_G0.7040.83
575_Y605_F0.7010.83
118_A222_Y0.6990.83
263_L285_T0.6990.83
379_L383_P0.6990.83
43_D46_V0.6990.83
359_A489_T0.6960.82
149_L158_V0.6960.82
265_G542_R0.6950.82
605_F609_H0.6940.82
466_N469_Q0.6910.82
522_T525_Y0.6910.82
87_R91_E0.6900.82
305_A312_N0.6900.82
469_Q517_K0.6890.82
25_Q169_V0.6880.82
213_P216_D0.6880.82
588_H591_D0.6880.82
152_T200_V0.6880.82
571_Q574_A0.6870.81
165_K332_H0.6870.81
83_Y101_S0.6860.81
74_I118_A0.6860.81
374_I472_D0.6850.81
237_L240_E0.6850.81
144_F504_V0.6850.81
185_M576_I0.6830.81
233_E516_L0.6830.81
8_F211_I0.6830.81
433_S438_L0.6830.81
106_L129_I0.6820.81
285_T314_S0.6810.81
537_E540_L0.6810.81
434_V437_Q0.6770.81
66_S132_K0.6760.80
472_D480_D0.6750.80
505_V508_V0.6730.80
241_V526_L0.6720.80
210_T220_K0.6720.80
260_G286_F0.6710.80
509_A526_L0.6710.80
158_V209_F0.6700.80
248_S505_V0.6700.80
530_A534_I0.6690.80
315_K351_E0.6690.80
87_R105_V0.6680.80
267_I528_R0.6680.80
193_P204_E0.6670.80
152_T156_D0.6640.79
524_K544_K0.6640.79
77_N495_E0.6630.79
67_Y107_L0.6630.79
71_T131_N0.6600.79
210_T218_T0.6590.79
41_F46_V0.6590.79
27_N47_G0.6580.79
69_D72_Y0.6580.79
115_E118_A0.6560.78
368_L506_F0.6550.78
176_I575_Y0.6550.78
584_L595_N0.6540.78
20_E42_H0.6540.78
325_E350_K0.6530.78
23_I26_M0.6530.78
303_E539_V0.6530.78
65_L99_T0.6520.78
486_D495_E0.6510.78
364_G367_E0.6510.78
4_F30_I0.6500.78
230_V237_L0.6490.78
470_Y474_H0.6490.78
328_K491_A0.6480.78
248_S251_V0.6480.78
2_C79_E0.6480.78
154_I159_Y0.6480.78
225_A473_I0.6470.77
262_F339_D0.6470.77
327_P607_I0.6460.77
423_Y426_N0.6460.77
308_L312_N0.6450.77
68_E112_H0.6450.77
300_V303_E0.6430.77
74_I110_Y0.6400.77
271_F533_G0.6390.77
469_Q473_I0.6390.77
65_L74_I0.6380.76
304_T542_R0.6380.76
190_V193_P0.6370.76
209_F219_F0.6360.76
244_A512_I0.6360.76
538_H541_N0.6340.76
345_L484_K0.6340.76
562_W603_L0.6340.76
245_I505_V0.6340.76
161_A170_A0.6340.76
174_I199_H0.6310.76
97_F104_E0.6310.76
262_F359_A0.6280.75
56_I99_T0.6280.75
559_M563_V0.6270.75
243_D246_Y0.6270.75
567_I581_V0.6260.75
181_L196_L0.6260.75
533_G540_L0.6250.75
117_A140_A0.6250.75
481_I484_K0.6240.75
37_S51_R0.6240.75
574_A578_K0.6240.75
50_F65_L0.6230.75
65_L68_E0.6230.75
410_S413_E0.6210.75
179_E198_A0.6210.75
190_V196_L0.6210.75
356_V494_L0.6210.75
382_K386_R0.6200.74
303_E307_A0.6200.74
568_Q582_L0.6190.74
363_E498_V0.6190.74
334_D338_A0.6170.74
342_A484_K0.6170.74
393_K397_H0.6160.74
328_K331_W0.6160.74
50_F76_F0.6150.74
188_Q601_T0.6150.74
407_R412_L0.6150.74
54_S58_V0.6140.74
546_G554_W0.6130.74
374_I548_P0.6130.74
292_Q295_F0.6110.73
65_L76_F0.6110.73
21_E25_Q0.6110.73
118_A129_I0.6110.73
125_F143_P0.6100.73
307_A538_H0.6100.73
313_I351_E0.6100.73
522_T529_K0.6090.73
161_A167_L0.6090.73
310_I314_S0.6080.73
409_K413_E0.6080.73
546_G550_P0.6080.73
292_Q553_H0.6080.73
304_T310_I0.6070.73
524_K527_L0.6070.73
447_S450_D0.6070.73
62_G65_L0.6060.73
148_P486_D0.6060.73
116_E120_K0.6060.73
580_Y584_L0.6050.73
241_V244_A0.6050.73
323_M559_M0.6040.73
147_K486_D0.6030.72
327_P611_I0.6030.72
439_L443_N0.6030.72
20_E40_Y0.6030.72
197_D200_V0.6020.72
93_K96_T0.6020.72
90_L97_F0.6010.72
229_P237_L0.6000.72
184_Y605_F0.5980.72
66_S71_T0.5970.72
367_E547_F0.5950.71
482_L501_L0.5950.71
238_V241_V0.5950.71
588_H593_A0.5950.71
242_R531_A0.5930.71
189_F480_D0.5920.71
366_D524_K0.5910.71
262_F361_S0.5910.71
52_R63_Q0.5900.71
124_M498_V0.5900.71
265_G300_V0.5890.71
366_D544_K0.5890.71
603_L607_I0.5890.71
476_W480_D0.5880.70
41_F130_W0.5880.70
273_V276_A0.5880.70
347_F350_K0.5880.70
252_H549_V0.5860.70
516_L525_Y0.5860.70
422_R426_N0.5860.70
192_E202_K0.5860.70
23_I42_H0.5850.70
339_D485_A0.5850.70
107_L111_R0.5850.70
57_D60_N0.5850.70
86_L121_L0.5850.70
99_T104_E0.5840.70
341_A344_P0.5830.70
151_Y209_F0.5830.70
77_N83_Y0.5830.70
143_P252_H0.5830.70
485_A498_V0.5830.70
43_D73_W0.5830.70
481_I485_A0.5820.70
374_I378_P0.5810.70
345_L361_S0.5810.70
482_L498_V0.5810.70
58_V257_V0.5800.69
212_R218_T0.5790.69
147_K490_M0.5790.69
428_K431_E0.5760.69
390_G394_M0.5760.69
201_K219_F0.5760.69
288_V345_L0.5760.69
188_Q484_K0.5750.69
52_R256_D0.5750.69
359_A496_L0.5750.69
377_E380_S0.5740.69
238_V526_L0.5740.69
290_F344_P0.5740.69
435_K439_L0.5730.69
490_M495_E0.5720.68
339_D363_E0.5710.68
512_I526_L0.5710.68
2_C55_I0.5700.68
296_S316_V0.5700.68
330_V604_I0.5690.68
2_C52_R0.5680.68
19_Q22_L0.5680.68
340_P480_D0.5670.68
571_Q606_M0.5670.68
350_K492_N0.5670.68
178_K198_A0.5650.67
361_S498_V0.5650.67
477_M482_L0.5650.67
304_T308_L0.5650.67
91_E96_T0.5650.67
581_V602_V0.5640.67
57_D100_D0.5640.67
233_E239_K0.5630.67
188_Q339_D0.5630.67
434_V438_L0.5630.67
572_T606_M0.5620.67
191_P202_K0.5610.67
408_G411_L0.5610.67
22_L169_V0.5610.67
173_D199_H0.5600.67
267_I531_A0.5600.67
346_Y350_K0.5600.67
29_M331_W0.5590.67
573_D578_K0.5580.67
293_Q296_S0.5570.66
221_T474_H0.5570.66
274_S304_T0.5560.66
229_P511_K0.5560.66
262_F484_K0.5560.66
328_K332_H0.5550.66
363_E476_W0.5550.66
254_R259_V0.5540.66
5_V29_M0.5540.66
229_P232_T0.5540.66
216_D219_F0.5540.66
227_F510_S0.5530.66
83_Y99_T0.5530.66
395_L399_A0.5520.66
438_L444_P0.5520.66
542_R545_L0.5510.66
75_I160_F0.5510.66
326_L607_I0.5500.65
56_I60_N0.5500.65
464_D467_K0.5500.65
272_I513_P0.5500.65
249_V272_I0.5490.65
247_D503_K0.5490.65
59_E62_G0.5480.65
87_R100_D0.5480.65
22_L26_M0.5470.65
2_C35_P0.5470.65
147_K495_E0.5460.65
168_M200_V0.5460.65
482_L486_D0.5460.65
305_A310_I0.5450.65
288_V315_K0.5450.65
141_R145_G0.5450.65
224_K227_F0.5440.65
339_D480_D0.5440.65
355_H494_L0.5440.65
230_V511_K0.5440.65
146_I364_G0.5430.64
151_Y219_F0.5420.64
77_N486_D0.5410.64
50_F62_G0.5410.64
143_P222_Y0.5400.64
257_V490_M0.5400.64
363_E488_M0.5400.64
1_M6_G0.5400.64
192_E204_E0.5400.64
62_G99_T0.5400.64
328_K346_Y0.5380.64
315_K354_K0.5370.64
301_A312_N0.5360.63
80_I105_V0.5360.63
244_A248_S0.5360.63
25_Q28_Q0.5360.63
562_W566_I0.5360.63
225_A510_S0.5350.63
435_K438_L0.5350.63
41_F66_S0.5340.63
326_L604_I0.5340.63
422_R425_G0.5340.63
7_V22_L0.5340.63
153_T159_Y0.5330.63
91_E97_F0.5330.63
394_M397_H0.5330.63
329_I488_M0.5330.63
8_F18_D0.5330.63
1_M4_F0.5310.63
55_I79_E0.5310.63
372_Y490_M0.5300.63
348_V351_E0.5300.63
552_R588_H0.5290.62
516_L526_L0.5290.62
535_V539_V0.5290.62
110_Y113_Y0.5280.62
238_V525_Y0.5280.62
573_D610_S0.5280.62
184_Y600_W0.5280.62
50_F103_T0.5270.62
262_F485_A0.5260.62
409_K414_R0.5260.62
2_C372_Y0.5260.62
235_D238_V0.5250.62
345_L489_T0.5250.62
176_I181_L0.5240.62
361_S476_W0.5240.62
529_K541_N0.5240.62
84_I88_E0.5240.62
265_G304_T0.5230.62
79_E372_Y0.5220.61
110_Y134_D0.5220.61
259_V352_A0.5220.61
387_I392_K0.5210.61
263_L304_T0.5210.61
526_L530_A0.5210.61
55_I257_V0.5210.61
203_V206_G0.5210.61
53_L495_E0.5210.61
340_P551_I0.5200.61
35_P53_L0.5200.61
26_M51_R0.5200.61
288_V317_I0.5200.61
348_V363_E0.5200.61
143_P206_G0.5190.61
50_F59_E0.5190.61
53_L77_N0.5190.61
191_P194_S0.5190.61
52_R77_N0.5180.61
153_T157_Q0.5170.61
53_L63_Q0.5170.61
268_D366_D0.5160.61
237_L511_K0.5160.61
70_E132_K0.5160.61
569_E582_L0.5150.60
333_F487_K0.5150.60
202_K479_G0.5150.60
418_P421_D0.5140.60
245_I369_F0.5130.60
290_F550_P0.5130.60
410_S414_R0.5130.60
237_L526_L0.5120.60
180_A185_M0.5120.60
439_L444_P0.5110.60
8_F45_H0.5100.60
508_V526_L0.5100.60
164_R168_M0.5090.60
441_H445_N0.5090.60
85_E88_E0.5090.60
305_A314_S0.5090.60
121_L127_F0.5070.59
246_Y250_N0.5060.59
297_E344_P0.5050.59
334_D339_D0.5050.59
11_H18_D0.5050.59
77_N147_K0.5040.59
85_E247_D0.5040.59
52_R78_G0.5040.59
315_K321_E0.5040.59
35_P52_R0.5030.59
407_R411_L0.5020.58
5_V23_I0.5020.58
225_A506_F0.5020.58
363_E547_F0.5020.58
159_Y172_N0.5010.58
58_V255_S0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ct9A 2 0.7611 100 0.341 Contact Map
1q15A 3 0.7563 100 0.345 Contact Map
1jgtA 2 0.7468 100 0.362 Contact Map
1ao0A 3 0.6218 100 0.703 Contact Map
1xffA 2 0.3133 100 0.728 Contact Map
1te5A 2 0.2927 100 0.734 Contact Map
4amvA 2 0.7579 100 0.74 Contact Map
1ecfA 4 0.6693 100 0.741 Contact Map
3mdnA 4 0.2627 100 0.768 Contact Map
4zflA 5 0.2911 100 0.791 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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