ASNB - BACSU - GREMLIN Contacts

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ASNB - Asparagine synthetase [glutamine-hydrolyzing] 1

UniProt:	P54420	Sequences: MCGFVGVFNKHPLAQTADQEELIKQMNQMIVHRGPDSDGYFHDEHVGFGFRRLSIIDVENGGQPLSYEDETYWIIFNGEIYNYIELREELEAKGYTFNTDSDTEVLLATYRHYKEEAASKLRGMFAFLIWNKNDHVLYGARDPFGIKPLYYTTINDQVYFASERKSLMVAQNDIEIDKEALQQYMSFQFVPEPSTLDAHVKKVEPGSQFTIRPDGDITFKTYFKANFKPVQTEEDKLVKEVRDAIYDSVNVHMRSDVPVGSFLSGGIDSSFIVSVAKEFHPSLKTFSVGFEQQGFSEVDVAKETAAALGIENISKVISPEEYMNELPKIVWHFDDPLADPAAIPLYFVAKEAKKHVTVALSGEGADELFGGYNIYREPLSLKPFERIPSGLKKMLLHVAAVMPEGMRGKSLLERGCTPLQDRYIGNAKIFEESVKKQLLKHYNPNLSYRDVTKTYFTESSSYSDINKMQYVDIHTWMRGDILLKADKMTMANSLELRVPFLDKVVFDVASKIPDELKTKNGTTKYLLRKAAEGIVPEHVLNRKKLGFPVPIRHWLKNEMNEWVRNIIQESQTDAYIHKDYVLQLLEDHCADKADNSRKIWTVLIFMIWHSINIEKRYMPEELSHQPKEVIFV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	632 (605)
Sequences:	3328 (2771)
Seq/√Len:	112.6

ECOLI - ASNB
BACSU - ASNB ASNH ASNO

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
37_S	62_G	4.244	1.00
175_E	198_A	4.069	1.00
109_T	113_Y	3.844	1.00
244_A	508_V	3.743	1.00
27_N	49_G	3.720	1.00
284_K	311_E	3.579	1.00
261_S	273_V	3.576	1.00
271_F	531_A	3.339	1.00
23_I	47_G	3.306	1.00
302_K	314_S	3.215	1.00
89_E	120_K	3.190	1.00
139_G	149_L	3.138	1.00
95_Y	112_H	3.106	1.00
246_Y	278_E	3.072	1.00
177_D	194_S	3.041	1.00
66_S	73_W	3.006	1.00
136_V	212_R	2.969	1.00
116_E	119_S	2.967	1.00
146_I	498_V	2.967	1.00
74_I	103_T	2.914	1.00
144_F	506_F	2.875	1.00
93_K	112_H	2.790	1.00
245_I	275_V	2.731	1.00
136_V	210_T	2.708	1.00
242_R	533_G	2.684	1.00
128_L	139_G	2.627	1.00
529_K	532_E	2.589	1.00
165_K	334_D	2.547	1.00
113_Y	120_K	2.522	1.00
67_Y	111_R	2.492	1.00
303_E	538_H	2.481	1.00
234_E	529_K	2.469	1.00
109_T	117_A	2.458	1.00
159_Y	170_A	2.401	1.00
285_T	310_I	2.374	1.00
61_G	101_S	2.360	1.00
38_D	51_R	2.345	1.00
251_V	504_V	2.335	1.00
365_A	500_F	2.293	1.00
489_T	496_L	2.291	1.00
204_E	207_S	2.286	1.00
67_Y	71_T	2.271	1.00
287_S	301_A	2.265	1.00
143_P	503_K	2.251	1.00
203_V	209_F	2.251	1.00
204_E	219_F	2.204	1.00
302_K	306_A	2.188	1.00
158_V	211_I	2.172	1.00
117_A	121_L	2.167	1.00
260_G	356_V	2.156	1.00
146_I	252_H	2.147	1.00
139_G	209_F	2.146	1.00
6_G	160_F	2.134	1.00
84_I	254_R	2.102	1.00
118_A	208_Q	2.078	1.00
208_Q	220_K	2.068	1.00
247_D	504_V	2.045	1.00
351_E	354_K	2.038	1.00
71_T	133_N	2.034	1.00
95_Y	108_A	2.004	1.00
232_T	237_L	2.001	1.00
110_Y	129_I	1.994	1.00
233_E	236_K	1.984	1.00
504_V	507_D	1.978	1.00
606_M	610_S	1.972	1.00
234_E	516_L	1.963	1.00
72_Y	107_L	1.959	1.00
240_E	244_A	1.957	1.00
122_R	504_V	1.952	1.00
300_V	542_R	1.951	1.00
202_K	335_D	1.944	1.00
43_D	132_K	1.935	1.00
125_F	140_A	1.931	1.00
503_K	507_D	1.928	1.00
32_H	163_E	1.925	1.00
537_E	541_N	1.921	1.00
118_A	140_A	1.918	1.00
130_W	137_L	1.912	1.00
369_F	509_A	1.906	1.00
270_S	304_T	1.904	1.00
177_D	201_K	1.902	1.00
122_R	503_K	1.894	1.00
519_K	525_Y	1.888	1.00
242_R	530_A	1.885	1.00
67_Y	108_A	1.876	1.00
284_K	313_I	1.875	1.00
331_W	611_I	1.874	1.00
350_K	354_K	1.835	1.00
587_D	595_N	1.814	1.00
240_E	243_D	1.807	1.00
242_R	534_I	1.798	1.00
573_D	606_M	1.781	1.00
241_V	369_F	1.775	1.00
177_D	198_A	1.769	1.00
463_S	514_D	1.751	1.00
151_Y	201_K	1.749	1.00
353_K	357_T	1.746	1.00
115_E	220_K	1.744	1.00
237_L	512_I	1.742	1.00
525_Y	529_K	1.737	1.00
253_M	276_A	1.734	1.00
56_I	83_Y	1.729	1.00
69_D	111_R	1.724	1.00
375_Y	472_D	1.719	1.00
234_E	525_Y	1.718	1.00
248_S	252_H	1.718	1.00
241_V	508_V	1.716	1.00
83_Y	105_V	1.698	1.00
363_E	484_K	1.688	1.00
5_V	26_M	1.687	1.00
73_W	132_K	1.685	1.00
159_Y	167_L	1.677	1.00
247_D	251_V	1.673	1.00
207_S	221_T	1.667	1.00
88_E	91_E	1.649	1.00
118_A	138_Y	1.648	1.00
109_T	121_L	1.646	1.00
285_T	312_N	1.646	1.00
388_P	392_K	1.639	1.00
122_R	247_D	1.630	1.00
328_K	350_K	1.610	1.00
532_E	541_N	1.608	1.00
106_L	121_L	1.598	1.00
273_V	310_I	1.591	1.00
76_F	80_I	1.589	1.00
207_S	219_F	1.587	1.00
240_E	508_V	1.580	1.00
5_V	27_N	1.570	1.00
108_A	111_R	1.569	1.00
532_E	537_E	1.563	1.00
301_A	305_A	1.558	1.00
588_H	594_D	1.542	1.00
223_F	507_D	1.542	1.00
117_A	138_Y	1.540	1.00
135_H	213_P	1.536	1.00
271_F	530_A	1.529	1.00
349_A	489_T	1.528	1.00
83_Y	254_R	1.524	1.00
533_G	537_E	1.512	1.00
110_Y	117_A	1.510	1.00
154_I	157_Q	1.507	1.00
130_W	135_H	1.501	1.00
5_V	49_G	1.496	1.00
80_I	106_L	1.493	1.00
209_F	217_I	1.487	1.00
106_L	117_A	1.476	1.00
115_E	210_T	1.476	1.00
320_E	324_N	1.473	1.00
89_E	113_Y	1.472	1.00
37_S	50_F	1.472	1.00
246_Y	279_F	1.459	1.00
508_V	512_I	1.444	1.00
122_R	502_D	1.441	1.00
74_I	107_L	1.437	1.00
127_F	140_A	1.436	1.00
161_A	166_S	1.436	1.00
27_N	51_R	1.424	1.00
115_E	138_Y	1.421	1.00
61_G	99_T	1.420	1.00
68_E	108_A	1.414	1.00
59_E	99_T	1.413	1.00
252_H	498_V	1.405	1.00
244_A	505_V	1.404	1.00
55_I	358_V	1.402	1.00
246_Y	275_V	1.398	1.00
23_I	49_G	1.392	1.00
245_I	500_F	1.390	1.00
71_T	134_D	1.388	1.00
239_K	533_G	1.388	1.00
273_V	285_T	1.385	1.00
24_K	28_Q	1.384	1.00
83_Y	100_D	1.383	1.00
234_E	519_K	1.374	1.00
138_Y	208_Q	1.373	1.00
261_S	285_T	1.373	1.00
48_F	160_F	1.368	1.00
76_F	103_T	1.354	1.00
138_Y	210_T	1.352	1.00
6_G	128_L	1.350	1.00
122_R	251_V	1.347	1.00
30_I	166_S	1.340	1.00
348_V	352_A	1.340	1.00
93_K	113_Y	1.334	1.00
463_S	466_N	1.333	1.00
251_V	254_R	1.333	1.00
238_V	530_A	1.332	1.00
65_L	107_L	1.328	1.00
122_R	252_H	1.325	1.00
332_H	491_A	1.303	0.99
68_E	111_R	1.303	0.99
74_I	127_F	1.302	0.99
110_Y	138_Y	1.297	0.99
206_G	223_F	1.295	0.99
241_V	505_V	1.287	0.99
28_Q	51_R	1.286	0.99
192_E	479_G	1.284	0.99
238_V	529_K	1.282	0.99
106_L	127_F	1.282	0.99
72_Y	111_R	1.281	0.99
42_H	47_G	1.266	0.99
232_T	236_K	1.265	0.99
370_G	518_T	1.261	0.99
352_A	359_A	1.261	0.99
234_E	238_V	1.260	0.99
22_L	171_Q	1.257	0.99
237_L	516_L	1.254	0.99
74_I	129_I	1.250	0.99
39_G	62_G	1.241	0.99
30_I	51_R	1.241	0.99
27_N	40_Y	1.236	0.99
18_D	47_G	1.235	0.99
276_A	283_L	1.234	0.99
71_T	111_R	1.229	0.99
270_S	300_V	1.228	0.99
140_A	208_Q	1.226	0.99
31_V	51_R	1.224	0.99
333_F	488_M	1.220	0.99
24_K	38_D	1.220	0.99
89_E	93_K	1.213	0.99
240_E	511_K	1.210	0.99
466_N	517_K	1.210	0.99
171_Q	174_I	1.208	0.99
128_L	160_F	1.203	0.99
564_R	586_E	1.195	0.99
530_A	533_G	1.192	0.99
126_A	149_L	1.186	0.99
127_F	138_Y	1.185	0.99
272_I	500_F	1.181	0.99
275_V	534_I	1.177	0.99
363_E	485_A	1.171	0.99
286_F	355_H	1.159	0.99
185_M	605_F	1.157	0.99
583_Q	587_D	1.156	0.99
124_M	252_H	1.156	0.99
291_E	318_S	1.156	0.99
289_G	316_V	1.154	0.99
273_V	308_L	1.154	0.99
560_N	564_R	1.150	0.99
56_I	254_R	1.146	0.99
24_K	40_Y	1.144	0.99
183_Q	194_S	1.141	0.99
181_L	605_F	1.139	0.99
224_K	474_H	1.138	0.99
277_K	308_L	1.138	0.99
83_Y	87_R	1.135	0.99
110_Y	131_N	1.135	0.99
168_M	174_I	1.132	0.99
74_I	106_L	1.130	0.99
8_F	46_V	1.129	0.99
6_G	139_G	1.127	0.99
244_A	504_V	1.121	0.98
117_A	127_F	1.119	0.98
72_Y	110_Y	1.117	0.98
582_L	586_E	1.114	0.98
153_T	201_K	1.108	0.98
370_G	469_Q	1.105	0.98
274_S	308_L	1.102	0.98
500_F	527_L	1.098	0.98
289_G	298_V	1.096	0.98
68_E	95_Y	1.089	0.98
71_T	132_K	1.089	0.98
544_K	547_F	1.088	0.98
29_M	169_V	1.083	0.98
242_R	246_Y	1.079	0.98
300_V	304_T	1.079	0.98
20_E	24_K	1.078	0.98
26_M	170_A	1.078	0.98
505_V	509_A	1.077	0.98
247_D	250_N	1.076	0.98
175_E	199_H	1.075	0.98
72_Y	133_N	1.074	0.98
67_Y	72_Y	1.071	0.98
241_V	509_A	1.071	0.98
248_S	502_D	1.071	0.98
560_N	589_C	1.070	0.98
37_S	54_S	1.069	0.98
550_P	554_W	1.067	0.98
298_V	314_S	1.065	0.98
150_Y	487_K	1.061	0.98
339_D	484_K	1.060	0.98
321_E	324_N	1.056	0.98
577_H	580_Y	1.055	0.98
124_M	146_I	1.054	0.98
255_S	259_V	1.049	0.98
272_I	360_L	1.048	0.98
65_L	103_T	1.046	0.98
485_A	496_L	1.045	0.98
48_F	75_I	1.043	0.98
27_N	38_D	1.041	0.97
261_S	276_A	1.033	0.97
513_P	516_L	1.033	0.97
129_I	138_Y	1.030	0.97
2_C	77_N	1.030	0.97
87_R	97_F	1.029	0.97
522_T	528_R	1.028	0.97
4_F	50_F	1.026	0.97
232_T	240_E	1.023	0.97
85_E	254_R	1.019	0.97
241_V	245_I	1.016	0.97
244_A	247_D	1.013	0.97
139_G	160_F	1.012	0.97
224_K	470_Y	1.010	0.97
341_A	484_K	1.008	0.97
118_A	127_F	1.007	0.97
259_V	358_V	1.000	0.97
30_I	161_A	0.999	0.97
575_Y	609_H	0.998	0.97
3_G	33_R	0.994	0.97
108_A	112_H	0.994	0.97
97_F	105_V	0.993	0.97
361_S	496_L	0.991	0.97
153_T	158_V	0.987	0.97
22_L	170_A	0.984	0.96
8_F	137_L	0.984	0.96
66_S	70_E	0.981	0.96
110_Y	115_E	0.980	0.96
177_D	180_A	0.979	0.96
270_S	535_V	0.978	0.96
574_A	606_M	0.975	0.96
41_F	73_W	0.974	0.96
437_Q	440_K	0.970	0.96
94_G	97_F	0.969	0.96
72_Y	134_D	0.969	0.96
124_M	147_K	0.966	0.96
325_E	347_F	0.965	0.96
291_E	316_V	0.956	0.96
144_F	473_I	0.953	0.96
234_E	237_L	0.950	0.96
167_L	200_V	0.942	0.95
56_I	255_S	0.941	0.95
576_I	581_V	0.941	0.95
67_Y	70_E	0.930	0.95
203_V	219_F	0.929	0.95
303_E	306_A	0.929	0.95
91_E	94_G	0.929	0.95
250_N	279_F	0.928	0.95
282_S	311_E	0.927	0.95
298_V	316_V	0.926	0.95
345_L	485_A	0.923	0.95
183_Q	191_P	0.923	0.95
260_G	352_A	0.921	0.95
588_H	595_N	0.917	0.95
221_T	224_K	0.914	0.95
556_K	588_H	0.910	0.95
564_R	582_L	0.910	0.95
262_F	352_A	0.908	0.94
81_Y	124_M	0.908	0.94
84_I	100_D	0.905	0.94
131_N	134_D	0.904	0.94
72_Y	108_A	0.902	0.94
31_V	38_D	0.902	0.94
344_P	484_K	0.902	0.94
552_R	556_K	0.900	0.94
27_N	30_I	0.898	0.94
164_R	195_T	0.898	0.94
565_N	568_Q	0.898	0.94
242_R	275_V	0.898	0.94
28_Q	38_D	0.897	0.94
245_I	271_F	0.893	0.94
67_Y	73_W	0.893	0.94
245_I	531_A	0.893	0.94
257_V	358_V	0.891	0.94
4_F	75_I	0.891	0.94
333_F	337_L	0.889	0.94
345_L	488_M	0.889	0.94
334_D	487_K	0.888	0.94
9_N	18_D	0.888	0.94
67_Y	95_Y	0.885	0.94
128_L	209_F	0.884	0.94
238_V	242_R	0.883	0.94
58_V	256_D	0.883	0.94
106_L	118_A	0.883	0.94
82_N	85_E	0.877	0.93
90_L	113_Y	0.876	0.93
7_V	159_Y	0.875	0.93
276_A	360_L	0.873	0.93
70_E	98_N	0.873	0.93
368_L	509_A	0.873	0.93
23_I	27_N	0.873	0.93
206_G	222_Y	0.871	0.93
522_T	541_N	0.871	0.93
241_V	527_L	0.869	0.93
151_Y	158_V	0.867	0.93
238_V	533_G	0.866	0.93
37_S	60_N	0.866	0.93
259_V	357_T	0.865	0.93
71_T	108_A	0.865	0.93
127_F	139_G	0.865	0.93
31_V	493_S	0.855	0.93
115_E	136_V	0.854	0.92
585_L	589_C	0.852	0.92
239_K	243_D	0.851	0.92
358_V	497_R	0.850	0.92
341_A	363_E	0.848	0.92
352_A	356_V	0.847	0.92
363_E	481_I	0.845	0.92
486_D	490_M	0.845	0.92
483_L	487_K	0.844	0.92
296_S	299_D	0.844	0.92
26_M	29_M	0.844	0.92
45_H	135_H	0.843	0.92
164_R	197_D	0.837	0.92
588_H	599_I	0.836	0.92
304_T	539_V	0.835	0.92
37_S	61_G	0.835	0.92
439_L	442_Y	0.832	0.91
246_Y	534_I	0.831	0.91
337_L	363_E	0.831	0.91
149_L	203_V	0.828	0.91
587_D	592_K	0.827	0.91
23_I	40_Y	0.827	0.91
7_V	18_D	0.826	0.91
165_K	331_W	0.825	0.91
587_D	593_A	0.825	0.91
278_E	534_I	0.825	0.91
109_T	120_K	0.824	0.91
578_K	582_L	0.823	0.91
113_Y	117_A	0.816	0.91
286_F	313_I	0.808	0.90
158_V	203_V	0.807	0.90
580_Y	583_Q	0.806	0.90
5_V	30_I	0.805	0.90
39_G	51_R	0.803	0.90
115_E	208_Q	0.801	0.90
164_R	200_V	0.801	0.90
265_G	287_S	0.799	0.90
565_N	569_E	0.797	0.90
535_V	540_L	0.796	0.90
333_F	342_A	0.794	0.89
95_Y	111_R	0.792	0.89
528_R	541_N	0.792	0.89
346_Y	491_A	0.790	0.89
345_L	363_E	0.790	0.89
442_Y	446_L	0.790	0.89
275_V	505_V	0.790	0.89
56_I	101_S	0.788	0.89
237_L	508_V	0.787	0.89
27_N	31_V	0.786	0.89
339_D	345_L	0.785	0.89
134_D	212_R	0.784	0.89
552_R	596_S	0.782	0.89
139_G	158_V	0.778	0.89
39_G	61_G	0.778	0.89
211_I	217_I	0.777	0.88
252_H	502_D	0.777	0.88
564_R	585_L	0.776	0.88
234_E	526_L	0.775	0.88
338_A	601_T	0.774	0.88
586_E	590_A	0.773	0.88
337_L	341_A	0.772	0.88
437_Q	442_Y	0.771	0.88
508_V	511_K	0.770	0.88
128_L	137_L	0.770	0.88
212_R	215_G	0.769	0.88
262_F	349_A	0.767	0.88
179_E	194_S	0.766	0.88
237_L	513_P	0.766	0.88
571_Q	610_S	0.764	0.88
321_E	350_K	0.764	0.88
249_V	276_A	0.762	0.87
257_V	357_T	0.762	0.87
318_S	321_E	0.762	0.87
367_E	372_Y	0.760	0.87
476_W	481_I	0.759	0.87
68_E	71_T	0.754	0.87
88_E	92_A	0.753	0.87
143_P	223_F	0.753	0.87
109_T	112_H	0.753	0.87
245_I	527_L	0.752	0.87
84_I	105_V	0.752	0.87
241_V	530_A	0.752	0.87
313_I	355_H	0.752	0.87
144_F	500_F	0.751	0.87
5_V	161_A	0.751	0.87
433_S	436_K	0.749	0.87
545_L	548_P	0.749	0.87
83_Y	97_F	0.747	0.86
7_V	19_Q	0.747	0.86
29_M	166_S	0.746	0.86
606_M	609_H	0.746	0.86
531_A	534_I	0.745	0.86
286_F	356_V	0.745	0.86
82_N	86_L	0.742	0.86
7_V	170_A	0.740	0.86
346_Y	492_N	0.738	0.86
523_T	528_R	0.738	0.86
152_T	167_L	0.737	0.86
36_D	357_T	0.737	0.86
359_A	494_L	0.737	0.86
552_R	594_D	0.736	0.86
9_N	12_P	0.736	0.86
91_E	100_D	0.734	0.85
442_Y	445_N	0.731	0.85
287_S	298_V	0.731	0.85
144_F	223_F	0.730	0.85
157_Q	170_A	0.729	0.85
60_N	99_T	0.729	0.85
274_S	534_I	0.729	0.85
81_Y	147_K	0.727	0.85
85_E	251_V	0.727	0.85
28_Q	31_V	0.723	0.85
21_E	24_K	0.721	0.84
77_N	372_Y	0.721	0.84
275_V	279_F	0.719	0.84
9_N	157_Q	0.719	0.84
563_V	585_L	0.718	0.84
466_N	514_D	0.718	0.84
56_I	84_I	0.715	0.84
289_G	301_A	0.714	0.84
430_F	434_V	0.714	0.84
374_I	377_E	0.712	0.84
562_W	565_N	0.712	0.84
566_I	607_I	0.711	0.84
148_P	162_S	0.709	0.83
232_T	512_I	0.707	0.83
37_S	75_I	0.707	0.83
595_N	598_K	0.706	0.83
433_S	437_Q	0.706	0.83
531_A	535_V	0.706	0.83
364_G	501_L	0.705	0.83
258_P	357_T	0.705	0.83
233_E	237_L	0.705	0.83
270_S	542_R	0.704	0.83
22_L	25_Q	0.704	0.83
480_D	546_G	0.704	0.83
575_Y	605_F	0.701	0.83
118_A	222_Y	0.699	0.83
263_L	285_T	0.699	0.83
379_L	383_P	0.699	0.83
43_D	46_V	0.699	0.83
359_A	489_T	0.696	0.82
149_L	158_V	0.696	0.82
265_G	542_R	0.695	0.82
605_F	609_H	0.694	0.82
466_N	469_Q	0.691	0.82
522_T	525_Y	0.691	0.82
87_R	91_E	0.690	0.82
305_A	312_N	0.690	0.82
469_Q	517_K	0.689	0.82
25_Q	169_V	0.688	0.82
213_P	216_D	0.688	0.82
588_H	591_D	0.688	0.82
152_T	200_V	0.688	0.82
571_Q	574_A	0.687	0.81
165_K	332_H	0.687	0.81
83_Y	101_S	0.686	0.81
74_I	118_A	0.686	0.81
374_I	472_D	0.685	0.81
237_L	240_E	0.685	0.81
144_F	504_V	0.685	0.81
185_M	576_I	0.683	0.81
233_E	516_L	0.683	0.81
8_F	211_I	0.683	0.81
433_S	438_L	0.683	0.81
106_L	129_I	0.682	0.81
285_T	314_S	0.681	0.81
537_E	540_L	0.681	0.81
434_V	437_Q	0.677	0.81
66_S	132_K	0.676	0.80
472_D	480_D	0.675	0.80
505_V	508_V	0.673	0.80
241_V	526_L	0.672	0.80
210_T	220_K	0.672	0.80
260_G	286_F	0.671	0.80
509_A	526_L	0.671	0.80
158_V	209_F	0.670	0.80
248_S	505_V	0.670	0.80
530_A	534_I	0.669	0.80
315_K	351_E	0.669	0.80
87_R	105_V	0.668	0.80
267_I	528_R	0.668	0.80
193_P	204_E	0.667	0.80
152_T	156_D	0.664	0.79
524_K	544_K	0.664	0.79
77_N	495_E	0.663	0.79
67_Y	107_L	0.663	0.79
71_T	131_N	0.660	0.79
210_T	218_T	0.659	0.79
41_F	46_V	0.659	0.79
27_N	47_G	0.658	0.79
69_D	72_Y	0.658	0.79
115_E	118_A	0.656	0.78
368_L	506_F	0.655	0.78
176_I	575_Y	0.655	0.78
584_L	595_N	0.654	0.78
20_E	42_H	0.654	0.78
325_E	350_K	0.653	0.78
23_I	26_M	0.653	0.78
303_E	539_V	0.653	0.78
65_L	99_T	0.652	0.78
486_D	495_E	0.651	0.78
364_G	367_E	0.651	0.78
4_F	30_I	0.650	0.78
230_V	237_L	0.649	0.78
470_Y	474_H	0.649	0.78
328_K	491_A	0.648	0.78
248_S	251_V	0.648	0.78
2_C	79_E	0.648	0.78
154_I	159_Y	0.648	0.78
225_A	473_I	0.647	0.77
262_F	339_D	0.647	0.77
327_P	607_I	0.646	0.77
423_Y	426_N	0.646	0.77
308_L	312_N	0.645	0.77
68_E	112_H	0.645	0.77
300_V	303_E	0.643	0.77
74_I	110_Y	0.640	0.77
271_F	533_G	0.639	0.77
469_Q	473_I	0.639	0.77
65_L	74_I	0.638	0.76
304_T	542_R	0.638	0.76
190_V	193_P	0.637	0.76
209_F	219_F	0.636	0.76
244_A	512_I	0.636	0.76
538_H	541_N	0.634	0.76
345_L	484_K	0.634	0.76
562_W	603_L	0.634	0.76
245_I	505_V	0.634	0.76
161_A	170_A	0.634	0.76
174_I	199_H	0.631	0.76
97_F	104_E	0.631	0.76
262_F	359_A	0.628	0.75
56_I	99_T	0.628	0.75
559_M	563_V	0.627	0.75
243_D	246_Y	0.627	0.75
567_I	581_V	0.626	0.75
181_L	196_L	0.626	0.75
533_G	540_L	0.625	0.75
117_A	140_A	0.625	0.75
481_I	484_K	0.624	0.75
37_S	51_R	0.624	0.75
574_A	578_K	0.624	0.75
50_F	65_L	0.623	0.75
65_L	68_E	0.623	0.75
410_S	413_E	0.621	0.75
179_E	198_A	0.621	0.75
190_V	196_L	0.621	0.75
356_V	494_L	0.621	0.75
382_K	386_R	0.620	0.74
303_E	307_A	0.620	0.74
568_Q	582_L	0.619	0.74
363_E	498_V	0.619	0.74
334_D	338_A	0.617	0.74
342_A	484_K	0.617	0.74
393_K	397_H	0.616	0.74
328_K	331_W	0.616	0.74
50_F	76_F	0.615	0.74
188_Q	601_T	0.615	0.74
407_R	412_L	0.615	0.74
54_S	58_V	0.614	0.74
546_G	554_W	0.613	0.74
374_I	548_P	0.613	0.74
292_Q	295_F	0.611	0.73
65_L	76_F	0.611	0.73
21_E	25_Q	0.611	0.73
118_A	129_I	0.611	0.73
125_F	143_P	0.610	0.73
307_A	538_H	0.610	0.73
313_I	351_E	0.610	0.73
522_T	529_K	0.609	0.73
161_A	167_L	0.609	0.73
310_I	314_S	0.608	0.73
409_K	413_E	0.608	0.73
546_G	550_P	0.608	0.73
292_Q	553_H	0.608	0.73
304_T	310_I	0.607	0.73
524_K	527_L	0.607	0.73
447_S	450_D	0.607	0.73
62_G	65_L	0.606	0.73
148_P	486_D	0.606	0.73
116_E	120_K	0.606	0.73
580_Y	584_L	0.605	0.73
241_V	244_A	0.605	0.73
323_M	559_M	0.604	0.73
147_K	486_D	0.603	0.72
327_P	611_I	0.603	0.72
439_L	443_N	0.603	0.72
20_E	40_Y	0.603	0.72
197_D	200_V	0.602	0.72
93_K	96_T	0.602	0.72
90_L	97_F	0.601	0.72
229_P	237_L	0.600	0.72
184_Y	605_F	0.598	0.72
66_S	71_T	0.597	0.72
367_E	547_F	0.595	0.71
482_L	501_L	0.595	0.71
238_V	241_V	0.595	0.71
588_H	593_A	0.595	0.71
242_R	531_A	0.593	0.71
189_F	480_D	0.592	0.71
366_D	524_K	0.591	0.71
262_F	361_S	0.591	0.71
52_R	63_Q	0.590	0.71
124_M	498_V	0.590	0.71
265_G	300_V	0.589	0.71
366_D	544_K	0.589	0.71
603_L	607_I	0.589	0.71
476_W	480_D	0.588	0.70
41_F	130_W	0.588	0.70
273_V	276_A	0.588	0.70
347_F	350_K	0.588	0.70
252_H	549_V	0.586	0.70
516_L	525_Y	0.586	0.70
422_R	426_N	0.586	0.70
192_E	202_K	0.586	0.70
23_I	42_H	0.585	0.70
339_D	485_A	0.585	0.70
107_L	111_R	0.585	0.70
57_D	60_N	0.585	0.70
86_L	121_L	0.585	0.70
99_T	104_E	0.584	0.70
341_A	344_P	0.583	0.70
151_Y	209_F	0.583	0.70
77_N	83_Y	0.583	0.70
143_P	252_H	0.583	0.70
485_A	498_V	0.583	0.70
43_D	73_W	0.583	0.70
481_I	485_A	0.582	0.70
374_I	378_P	0.581	0.70
345_L	361_S	0.581	0.70
482_L	498_V	0.581	0.70
58_V	257_V	0.580	0.69
212_R	218_T	0.579	0.69
147_K	490_M	0.579	0.69
428_K	431_E	0.576	0.69
390_G	394_M	0.576	0.69
201_K	219_F	0.576	0.69
288_V	345_L	0.576	0.69
188_Q	484_K	0.575	0.69
52_R	256_D	0.575	0.69
359_A	496_L	0.575	0.69
377_E	380_S	0.574	0.69
238_V	526_L	0.574	0.69
290_F	344_P	0.574	0.69
435_K	439_L	0.573	0.69
490_M	495_E	0.572	0.68
339_D	363_E	0.571	0.68
512_I	526_L	0.571	0.68
2_C	55_I	0.570	0.68
296_S	316_V	0.570	0.68
330_V	604_I	0.569	0.68
2_C	52_R	0.568	0.68
19_Q	22_L	0.568	0.68
340_P	480_D	0.567	0.68
571_Q	606_M	0.567	0.68
350_K	492_N	0.567	0.68
178_K	198_A	0.565	0.67
361_S	498_V	0.565	0.67
477_M	482_L	0.565	0.67
304_T	308_L	0.565	0.67
91_E	96_T	0.565	0.67
581_V	602_V	0.564	0.67
57_D	100_D	0.564	0.67
233_E	239_K	0.563	0.67
188_Q	339_D	0.563	0.67
434_V	438_L	0.563	0.67
572_T	606_M	0.562	0.67
191_P	202_K	0.561	0.67
408_G	411_L	0.561	0.67
22_L	169_V	0.561	0.67
173_D	199_H	0.560	0.67
267_I	531_A	0.560	0.67
346_Y	350_K	0.560	0.67
29_M	331_W	0.559	0.67
573_D	578_K	0.558	0.67
293_Q	296_S	0.557	0.66
221_T	474_H	0.557	0.66
274_S	304_T	0.556	0.66
229_P	511_K	0.556	0.66
262_F	484_K	0.556	0.66
328_K	332_H	0.555	0.66
363_E	476_W	0.555	0.66
254_R	259_V	0.554	0.66
5_V	29_M	0.554	0.66
229_P	232_T	0.554	0.66
216_D	219_F	0.554	0.66
227_F	510_S	0.553	0.66
83_Y	99_T	0.553	0.66
395_L	399_A	0.552	0.66
438_L	444_P	0.552	0.66
542_R	545_L	0.551	0.66
75_I	160_F	0.551	0.66
326_L	607_I	0.550	0.65
56_I	60_N	0.550	0.65
464_D	467_K	0.550	0.65
272_I	513_P	0.550	0.65
249_V	272_I	0.549	0.65
247_D	503_K	0.549	0.65
59_E	62_G	0.548	0.65
87_R	100_D	0.548	0.65
22_L	26_M	0.547	0.65
2_C	35_P	0.547	0.65
147_K	495_E	0.546	0.65
168_M	200_V	0.546	0.65
482_L	486_D	0.546	0.65
305_A	310_I	0.545	0.65
288_V	315_K	0.545	0.65
141_R	145_G	0.545	0.65
224_K	227_F	0.544	0.65
339_D	480_D	0.544	0.65
355_H	494_L	0.544	0.65
230_V	511_K	0.544	0.65
146_I	364_G	0.543	0.64
151_Y	219_F	0.542	0.64
77_N	486_D	0.541	0.64
50_F	62_G	0.541	0.64
143_P	222_Y	0.540	0.64
257_V	490_M	0.540	0.64
363_E	488_M	0.540	0.64
1_M	6_G	0.540	0.64
192_E	204_E	0.540	0.64
62_G	99_T	0.540	0.64
328_K	346_Y	0.538	0.64
315_K	354_K	0.537	0.64
301_A	312_N	0.536	0.63
80_I	105_V	0.536	0.63
244_A	248_S	0.536	0.63
25_Q	28_Q	0.536	0.63
562_W	566_I	0.536	0.63
225_A	510_S	0.535	0.63
435_K	438_L	0.535	0.63
41_F	66_S	0.534	0.63
326_L	604_I	0.534	0.63
422_R	425_G	0.534	0.63
7_V	22_L	0.534	0.63
153_T	159_Y	0.533	0.63
91_E	97_F	0.533	0.63
394_M	397_H	0.533	0.63
329_I	488_M	0.533	0.63
8_F	18_D	0.533	0.63
1_M	4_F	0.531	0.63
55_I	79_E	0.531	0.63
372_Y	490_M	0.530	0.63
348_V	351_E	0.530	0.63
552_R	588_H	0.529	0.62
516_L	526_L	0.529	0.62
535_V	539_V	0.529	0.62
110_Y	113_Y	0.528	0.62
238_V	525_Y	0.528	0.62
573_D	610_S	0.528	0.62
184_Y	600_W	0.528	0.62
50_F	103_T	0.527	0.62
262_F	485_A	0.526	0.62
409_K	414_R	0.526	0.62
2_C	372_Y	0.526	0.62
235_D	238_V	0.525	0.62
345_L	489_T	0.525	0.62
176_I	181_L	0.524	0.62
361_S	476_W	0.524	0.62
529_K	541_N	0.524	0.62
84_I	88_E	0.524	0.62
265_G	304_T	0.523	0.62
79_E	372_Y	0.522	0.61
110_Y	134_D	0.522	0.61
259_V	352_A	0.522	0.61
387_I	392_K	0.521	0.61
263_L	304_T	0.521	0.61
526_L	530_A	0.521	0.61
55_I	257_V	0.521	0.61
203_V	206_G	0.521	0.61
53_L	495_E	0.521	0.61
340_P	551_I	0.520	0.61
35_P	53_L	0.520	0.61
26_M	51_R	0.520	0.61
288_V	317_I	0.520	0.61
348_V	363_E	0.520	0.61
143_P	206_G	0.519	0.61
50_F	59_E	0.519	0.61
53_L	77_N	0.519	0.61
191_P	194_S	0.519	0.61
52_R	77_N	0.518	0.61
153_T	157_Q	0.517	0.61
53_L	63_Q	0.517	0.61
268_D	366_D	0.516	0.61
237_L	511_K	0.516	0.61
70_E	132_K	0.516	0.61
569_E	582_L	0.515	0.60
333_F	487_K	0.515	0.60
202_K	479_G	0.515	0.60
418_P	421_D	0.514	0.60
245_I	369_F	0.513	0.60
290_F	550_P	0.513	0.60
410_S	414_R	0.513	0.60
237_L	526_L	0.512	0.60
180_A	185_M	0.512	0.60
439_L	444_P	0.511	0.60
8_F	45_H	0.510	0.60
508_V	526_L	0.510	0.60
164_R	168_M	0.509	0.60
441_H	445_N	0.509	0.60
85_E	88_E	0.509	0.60
305_A	314_S	0.509	0.60
121_L	127_F	0.507	0.59
246_Y	250_N	0.506	0.59
297_E	344_P	0.505	0.59
334_D	339_D	0.505	0.59
11_H	18_D	0.505	0.59
77_N	147_K	0.504	0.59
85_E	247_D	0.504	0.59
52_R	78_G	0.504	0.59
315_K	321_E	0.504	0.59
35_P	52_R	0.503	0.59
407_R	411_L	0.502	0.58
5_V	23_I	0.502	0.58
225_A	506_F	0.502	0.58
363_E	547_F	0.502	0.58
159_Y	172_N	0.501	0.58
58_V	255_S	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
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HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1ct9A	2	0.7611	100	0.341	Contact Map
1q15A	3	0.7563	100	0.345	Contact Map
1jgtA	2	0.7468	100	0.362	Contact Map
1ao0A	3	0.6218	100	0.703	Contact Map
1xffA	2	0.3133	100	0.728	Contact Map
1te5A	2	0.2927	100	0.734	Contact Map
4amvA	2	0.7579	100	0.74	Contact Map
1ecfA	4	0.6693	100	0.741	Contact Map
3mdnA	4	0.2627	100	0.768	Contact Map
4zflA	5	0.2911	100	0.791	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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