PCKA - BACSU - GREMLIN Contacts

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PCKA - Phosphoenolpyruvate carboxykinase [ATP]

UniProt:	P54418	Sequences: MNSVDLTADLQALLTCPNVRHNLSAAQLTEKVLSRNEGILTSTGAVRATTGAYTGRSPKDKFIVEEESTKNKIDWGPVNQPISEEAFERLYTKVVSYLKERDELFVFEGFAGADEKYRLPITVVNEFAWHNLFARQLFIRPEGNDKKTVEQPFTILSAPHFKADPKTDGTHSETFIIVSFEKRTILIGGTEYAGEMKKSIFSIMNFLLPERDILSMHCSANVGEKGDVALFFGLSGTGKTTLSADADRKLIGDDEHGWSDTGVFNIEGGCYAKCIHLSEEKEPQIFNAIRFGSVLENVVVDEDTREANYDDSFYTENTRAAYPIHMINNIVTPSMAGHPSAIVFLTADAFGVLPPISKLTKEQAMYHFLSGYTSKLAGTERGVTSPETTFSTCFGSPFLPLPAHVYAEMLGKKIDEHGADVFLVNTGWTGGGYGTGERMKLSYTRAMVKAAIEGKLEDAEMITDDIFGLHIPAHVPGVPDHILQPENTWTNKEEYKEKAVYLANEFKENFKKFAHTDAIAQAGGPLV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	527 (510)
Sequences:	1605 (778)
Seq/√Len:	34.4

ECOLI - PCKA
BACSU - PCKA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
65_E	70_K	5.833	1.00
486_E	496_K	5.052	1.00
222_V	336_A	4.648	1.00
412_K	416_E	4.488	1.00
508_E	511_K	4.087	1.00
279_E	287_N	4.040	1.00
356_I	451_A	3.927	1.00
35_R	105_F	3.738	1.00
491_N	494_E	3.534	1.00
223_G	227_D	3.455	1.00
175_F	188_G	3.364	1.00
501_Y	505_E	3.286	1.00
108_E	122_T	3.189	1.00
49_T	314_Y	3.163	1.00
88_E	182_K	3.157	1.00
443_Y	479_P	3.066	1.00
276_H	310_D	3.066	1.00
358_K	420_D	3.059	1.00
120_P	152_P	3.015	1.00
462_I	484_Q	2.973	1.00
437_E	440_K	2.966	1.00
93_K	168_D	2.914	1.00
361_K	415_D	2.903	1.00
97_Y	160_H	2.870	1.00
498_K	501_Y	2.864	1.00
293_S	320_A	2.829	1.00
41_T	47_R	2.711	1.00
460_E	473_A	2.710	1.00
408_E	412_K	2.689	1.00
247_D	449_K	2.673	1.00
72_K	210_E	2.663	1.00
118_R	145_D	2.625	1.00
137_L	321_A	2.609	1.00
26_A	291_F	2.594	1.00
126_E	160_H	2.537	1.00
116_K	261_T	2.535	1.00
487_N	492_K	2.478	1.00
372_Y	388_T	2.474	1.00
42_S	306_E	2.467	1.00
463_T	470_H	2.460	1.00
462_I	473_A	2.450	1.00
125_N	131_N	2.409	1.00
511_K	514_A	2.401	1.00
66_E	181_E	2.394	1.00
338_H	417_H	2.393	1.00
20_R	103_E	2.377	0.99
66_E	73_I	2.343	0.99
341_A	422_F	2.299	0.99
420_D	457_E	2.280	0.99
356_I	447_M	2.257	0.99
179_S	182_K	2.225	0.99
98_L	158_A	2.189	0.99
432_G	435_T	2.181	0.99
84_E	181_E	2.171	0.99
35_R	103_E	2.147	0.99
29_T	40_L	2.145	0.99
32_V	46_V	2.064	0.98
91_Y	182_K	2.061	0.98
163_A	188_G	2.014	0.98
110_F	118_R	1.976	0.98
66_E	69_T	1.971	0.98
228_V	263_V	1.931	0.98
440_K	443_Y	1.914	0.98
53_Y	174_T	1.879	0.97
365_M	411_G	1.879	0.97
31_K	34_S	1.852	0.97
504_N	508_E	1.851	0.97
82_I	86_A	1.828	0.97
26_A	30_E	1.825	0.97
22_N	108_E	1.813	0.97
300_V	307_A	1.806	0.96
41_T	300_V	1.805	0.96
204_M	266_I	1.795	0.96
274_C	318_T	1.789	0.96
142_E	145_D	1.776	0.96
111_A	200_I	1.775	0.96
432_G	498_K	1.773	0.96
215_S	266_I	1.771	0.96
474_H	480_D	1.770	0.96
65_E	81_P	1.770	0.96
464_D	471_I	1.766	0.96
117_Y	211_R	1.763	0.96
122_T	151_Q	1.758	0.96
134_A	138_F	1.749	0.96
38_G	48_A	1.733	0.95
67_E	70_K	1.731	0.95
137_L	274_C	1.721	0.95
229_A	452_I	1.717	0.95
484_Q	487_N	1.716	0.95
146_K	149_V	1.709	0.95
347_A	376_L	1.702	0.95
48_A	130_H	1.695	0.95
91_Y	184_T	1.686	0.95
215_S	401_L	1.674	0.95
456_L	459_A	1.666	0.94
518_A	521_Q	1.657	0.94
281_K	441_L	1.641	0.94
30_E	291_F	1.632	0.94
123_V	134_A	1.624	0.94
447_M	451_A	1.619	0.93
275_I	312_S	1.618	0.93
68_S	181_E	1.613	0.93
344_F	421_V	1.601	0.93
210_E	401_L	1.581	0.93
83_S	86_A	1.579	0.93
347_A	428_W	1.578	0.93
301_D	306_E	1.574	0.92
429_T	488_T	1.567	0.92
93_K	167_T	1.557	0.92
94_V	158_A	1.550	0.92
140_R	325_H	1.540	0.92
66_E	72_K	1.537	0.92
289_I	309_Y	1.536	0.92
134_A	196_M	1.518	0.91
53_Y	381_R	1.518	0.91
69_T	181_E	1.516	0.91
59_K	77_P	1.512	0.91
82_I	177_I	1.510	0.91
300_V	304_T	1.508	0.91
165_P	170_T	1.504	0.91
117_Y	213_I	1.499	0.91
274_C	320_A	1.490	0.90
163_A	175_F	1.489	0.90
136_Q	321_A	1.488	0.90
429_T	439_M	1.456	0.89
295_L	320_A	1.456	0.89
47_R	300_V	1.451	0.89
106_V	124_V	1.451	0.89
251_I	336_A	1.448	0.89
262_G	338_H	1.442	0.89
32_V	128_A	1.431	0.88
30_E	34_S	1.425	0.88
121_I	149_V	1.424	0.88
31_K	105_F	1.423	0.88
30_E	304_T	1.422	0.88
324_I	334_S	1.414	0.88
518_A	522_A	1.404	0.87
370_S	509_N	1.404	0.87
130_H	193_A	1.404	0.87
494_E	498_K	1.403	0.87
464_D	469_L	1.400	0.87
439_M	482_I	1.378	0.86
97_Y	126_E	1.369	0.86
203_I	207_L	1.352	0.85
162_K	173_E	1.344	0.85
466_I	503_A	1.343	0.85
59_K	80_Q	1.336	0.85
463_T	468_G	1.333	0.84
138_F	200_I	1.330	0.84
249_K	331_V	1.329	0.84
107_F	131_N	1.328	0.84
33_L	40_L	1.317	0.84
24_S	27_Q	1.315	0.84
215_S	399_L	1.308	0.83
84_E	88_E	1.300	0.83
455_K	476_P	1.299	0.83
222_V	331_V	1.292	0.82
68_S	73_I	1.290	0.82
82_I	170_T	1.279	0.82
193_A	294_V	1.269	0.81
358_K	470_H	1.255	0.81
45_A	288_A	1.254	0.81
43_T	309_Y	1.244	0.80
284_Q	328_N	1.243	0.80
66_E	179_S	1.237	0.80
61_K	399_L	1.236	0.80
440_K	447_M	1.234	0.79
228_V	336_A	1.233	0.79
86_A	89_R	1.222	0.79
114_D	259_S	1.220	0.79
130_H	157_S	1.219	0.79
68_S	206_F	1.216	0.78
152_P	183_R	1.204	0.78
496_K	500_V	1.201	0.78
360_T	363_Q	1.199	0.77
21_H	108_E	1.198	0.77
108_E	151_Q	1.198	0.77
110_F	142_E	1.194	0.77
363_Q	468_G	1.190	0.77
492_K	496_K	1.182	0.76
96_S	99_K	1.180	0.76
37_E	128_A	1.175	0.76
18_N	103_E	1.175	0.76
13_L	16_C	1.174	0.76
362_E	519_I	1.172	0.76
67_E	181_E	1.172	0.76
464_D	468_G	1.169	0.76
23_L	27_Q	1.167	0.75
293_S	326_M	1.167	0.75
74_D	396_S	1.161	0.75
276_H	281_K	1.151	0.74
346_T	367_H	1.148	0.74
185_I	199_S	1.143	0.74
107_F	135_R	1.139	0.74
315_T	318_T	1.138	0.74
414_I	421_V	1.132	0.73
464_D	484_Q	1.130	0.73
25_A	135_R	1.128	0.73
115_E	335_M	1.124	0.73
349_A	386_P	1.119	0.72
228_V	337_G	1.114	0.72
140_R	324_I	1.111	0.72
20_R	23_L	1.105	0.71
299_V	314_Y	1.098	0.71
69_T	73_I	1.097	0.71
446_A	478_V	1.090	0.70
360_T	470_H	1.083	0.70
157_S	196_M	1.074	0.69
342_I	419_A	1.073	0.69
212_D	260_D	1.072	0.69
284_Q	287_N	1.072	0.69
125_N	196_M	1.071	0.69
176_I	190_T	1.071	0.69
227_D	340_S	1.068	0.69
460_E	474_H	1.064	0.68
414_I	419_A	1.061	0.68
455_K	459_A	1.057	0.68
87_F	182_K	1.056	0.68
347_A	350_F	1.048	0.67
94_V	161_F	1.043	0.67
27_Q	31_K	1.040	0.67
123_V	196_M	1.034	0.66
43_T	293_S	1.031	0.66
497_E	501_Y	1.030	0.66
88_E	91_Y	1.025	0.66
321_A	375_K	1.024	0.65
521_Q	524_G	1.023	0.65
350_F	505_E	1.023	0.65
20_R	31_K	1.016	0.65
69_T	72_K	1.014	0.65
470_H	473_A	1.012	0.64
137_L	294_V	1.012	0.64
206_F	210_E	1.012	0.64
408_E	517_D	1.011	0.64
39_I	300_V	1.010	0.64
141_P	145_D	1.003	0.64
101_R	126_E	1.000	0.64
225_K	228_V	0.997	0.63
65_E	69_T	0.994	0.63
231_F	242_L	0.993	0.63
462_I	487_N	0.988	0.63
33_L	38_G	0.986	0.62
136_Q	139_I	0.983	0.62
200_I	203_I	0.981	0.62
494_E	497_E	0.980	0.62
94_V	186_L	0.979	0.62
473_A	484_Q	0.976	0.62
278_S	281_K	0.973	0.61
178_V	202_S	0.967	0.61
493_E	497_E	0.966	0.61
343_V	448_V	0.965	0.61
484_Q	496_K	0.956	0.60
110_F	145_D	0.955	0.60
168_D	175_F	0.953	0.60
299_V	311_D	0.951	0.60
303_D	306_E	0.949	0.59
111_A	266_I	0.949	0.59
42_S	307_A	0.948	0.59
116_K	212_D	0.947	0.59
130_H	294_V	0.947	0.59
43_T	307_A	0.941	0.59
404_H	516_T	0.941	0.59
224_E	247_D	0.937	0.58
361_K	421_V	0.935	0.58
443_Y	447_M	0.932	0.58
65_E	71_N	0.929	0.58
149_V	152_P	0.917	0.57
222_V	228_V	0.916	0.57
446_A	450_A	0.916	0.57
401_L	405_V	0.912	0.56
155_I	200_I	0.910	0.56
65_E	83_S	0.910	0.56
63_I	202_S	0.907	0.56
119_L	207_L	0.905	0.56
507_K	524_G	0.904	0.56
138_F	175_F	0.903	0.56
52_A	173_E	0.902	0.56
94_V	188_G	0.902	0.56
74_D	403_A	0.901	0.55
424_V	451_A	0.899	0.55
163_A	168_D	0.899	0.55
366_Y	524_G	0.899	0.55
294_V	320_A	0.899	0.55
422_F	457_E	0.897	0.55
153_F	207_L	0.892	0.55
29_T	291_F	0.889	0.54
461_M	470_H	0.889	0.54
110_F	120_P	0.885	0.54
58_P	315_T	0.884	0.54
446_A	476_P	0.884	0.54
244_A	450_A	0.882	0.54
396_S	399_L	0.882	0.54
164_D	167_T	0.882	0.54
429_T	435_T	0.881	0.54
447_M	469_L	0.879	0.54
47_R	298_V	0.878	0.54
119_L	211_R	0.876	0.53
129_W	369_L	0.868	0.53
31_K	103_E	0.867	0.53
156_L	469_L	0.866	0.53
341_A	420_D	0.862	0.52
480_D	487_N	0.858	0.52
45_A	309_Y	0.858	0.52
224_E	249_K	0.852	0.51
163_A	170_T	0.849	0.51
38_G	46_V	0.849	0.51
201_F	205_N	0.848	0.51
142_E	146_K	0.848	0.51
294_V	321_A	0.847	0.51
342_I	413_K	0.846	0.51
119_L	153_F	0.846	0.51
98_L	104_L	0.845	0.51
274_C	307_A	0.843	0.51
508_E	522_A	0.842	0.50
295_L	307_A	0.841	0.50
289_I	320_A	0.840	0.50
135_R	140_R	0.837	0.50
466_I	500_V	0.837	0.50
288_A	293_S	0.837	0.50
59_K	164_D	0.834	0.50
153_F	183_R	0.833	0.50
202_S	400_P	0.832	0.50
29_T	33_L	0.830	0.49
288_A	309_Y	0.828	0.49
90_L	188_G	0.827	0.49
276_H	312_S	0.821	0.49
191_E	381_R	0.818	0.48
480_D	484_Q	0.815	0.48
247_D	284_Q	0.815	0.48
165_P	168_D	0.815	0.48
429_T	437_E	0.813	0.48
113_A	334_S	0.811	0.48
93_K	164_D	0.810	0.48
53_Y	62_F	0.809	0.48
226_G	372_Y	0.806	0.47
408_E	416_E	0.805	0.47
90_L	175_F	0.804	0.47
451_A	456_L	0.804	0.47
124_V	156_L	0.804	0.47
120_P	149_V	0.803	0.47
290_R	326_M	0.803	0.47
260_D	416_E	0.803	0.47
383_V	387_E	0.803	0.47
274_C	309_Y	0.800	0.47
72_K	206_F	0.799	0.47
214_L	409_M	0.798	0.47
72_K	401_L	0.796	0.47
263_V	336_A	0.794	0.46
291_F	304_T	0.794	0.46
370_S	392_T	0.792	0.46
491_N	497_E	0.790	0.46
129_W	193_A	0.789	0.46
84_E	179_S	0.786	0.46
213_I	257_G	0.786	0.46
134_A	155_I	0.786	0.46
278_S	396_S	0.779	0.45
68_S	210_E	0.778	0.45
46_V	330_I	0.776	0.45
424_V	448_V	0.773	0.45
22_N	122_T	0.773	0.45
21_H	122_T	0.770	0.44
152_P	211_R	0.770	0.44
93_K	161_F	0.763	0.44
168_D	188_G	0.760	0.44
90_L	163_A	0.758	0.43
88_E	179_S	0.755	0.43
412_K	487_N	0.754	0.43
286_F	306_E	0.753	0.43
284_Q	331_V	0.752	0.43
331_V	399_L	0.750	0.43
40_L	291_F	0.750	0.43
481_H	487_N	0.750	0.43
48_A	193_A	0.749	0.43
484_Q	490_T	0.742	0.42
32_V	330_I	0.740	0.42
94_V	175_F	0.740	0.42
63_I	180_F	0.739	0.42
278_S	441_L	0.738	0.42
278_S	310_D	0.736	0.42
490_T	494_E	0.736	0.42
23_L	131_N	0.735	0.41
52_A	263_V	0.734	0.41
462_I	471_I	0.731	0.41
392_T	516_T	0.731	0.41
34_S	493_E	0.727	0.41
63_I	73_I	0.727	0.41
214_L	412_K	0.726	0.41
520_A	523_G	0.726	0.41
330_I	365_M	0.725	0.41
459_A	473_A	0.722	0.40
459_A	476_P	0.722	0.40
73_I	181_E	0.722	0.40
91_Y	95_V	0.721	0.40
490_T	497_E	0.720	0.40
39_I	309_Y	0.719	0.40
74_D	402_P	0.716	0.40
302_E	490_T	0.716	0.40
68_S	72_K	0.715	0.40
369_L	392_T	0.714	0.40
67_E	493_E	0.714	0.40
24_S	95_V	0.713	0.40
20_R	35_R	0.712	0.40
61_K	202_S	0.711	0.39
308_N	311_D	0.710	0.39
163_A	190_T	0.710	0.39
145_D	152_P	0.709	0.39
129_W	170_T	0.708	0.39
375_K	387_E	0.708	0.39
162_K	165_P	0.707	0.39
145_D	149_V	0.704	0.39
183_R	207_L	0.704	0.39
349_A	378_G	0.703	0.39
178_V	185_I	0.702	0.39
132_L	321_A	0.702	0.39
295_L	298_V	0.701	0.39
129_W	208_L	0.701	0.39
207_L	396_S	0.699	0.39
117_Y	259_S	0.699	0.39
227_D	341_A	0.699	0.39
492_K	500_V	0.696	0.38
208_L	257_G	0.692	0.38
341_A	451_A	0.689	0.38
465_D	484_Q	0.688	0.38
466_I	496_K	0.688	0.38
220_A	263_V	0.687	0.38
94_V	204_M	0.685	0.37
388_T	505_E	0.685	0.37
123_V	155_I	0.681	0.37
413_K	417_H	0.681	0.37
503_A	525_P	0.678	0.37
84_E	182_K	0.678	0.37
246_A	449_K	0.678	0.37
23_L	107_F	0.678	0.37
381_R	397_P	0.675	0.37
357_S	367_H	0.675	0.37
287_N	290_R	0.674	0.37
324_I	342_I	0.674	0.37
249_K	330_I	0.673	0.36
58_P	381_R	0.673	0.36
185_I	210_E	0.672	0.36
144_N	286_F	0.670	0.36
74_D	448_V	0.670	0.36
246_A	284_Q	0.670	0.36
465_D	500_V	0.669	0.36
161_F	170_T	0.668	0.36
508_E	514_A	0.668	0.36
441_L	471_I	0.668	0.36
53_Y	91_Y	0.667	0.36
447_M	479_P	0.667	0.36
212_D	312_S	0.667	0.36
45_A	289_I	0.667	0.36
112_G	153_F	0.666	0.36
119_L	203_I	0.663	0.36
504_N	522_A	0.663	0.36
340_S	420_D	0.662	0.36
13_L	95_V	0.662	0.36
26_A	304_T	0.662	0.36
369_L	516_T	0.661	0.35
155_I	187_I	0.660	0.35
507_K	525_P	0.658	0.35
455_K	493_E	0.658	0.35
415_D	497_E	0.658	0.35
17_P	103_E	0.657	0.35
150_E	156_L	0.657	0.35
422_F	456_L	0.657	0.35
130_H	191_E	0.656	0.35
451_A	454_G	0.656	0.35
443_Y	481_H	0.656	0.35
76_G	274_C	0.654	0.35
205_N	216_M	0.652	0.35
47_R	387_E	0.652	0.35
173_E	381_R	0.650	0.35
106_V	514_A	0.650	0.35
392_T	401_L	0.647	0.34
362_E	389_T	0.645	0.34
115_E	212_D	0.645	0.34
43_T	288_A	0.644	0.34
61_K	176_I	0.642	0.34
421_V	441_L	0.641	0.34
457_E	480_D	0.640	0.34
70_K	81_P	0.637	0.34
17_P	20_R	0.637	0.34
274_C	399_L	0.636	0.34
96_S	166_K	0.636	0.34
50_T	62_F	0.634	0.33
66_E	70_K	0.633	0.33
493_E	496_K	0.632	0.33
70_K	476_P	0.631	0.33
433_Y	488_T	0.629	0.33
175_F	186_L	0.629	0.33
301_D	342_I	0.629	0.33
153_F	203_I	0.629	0.33
112_G	193_A	0.627	0.33
383_V	386_P	0.625	0.33
374_S	383_V	0.624	0.33
361_K	411_G	0.624	0.33
222_V	227_D	0.621	0.32
78_V	396_S	0.619	0.32
153_F	172_S	0.619	0.32
144_N	149_V	0.618	0.32
62_F	171_H	0.618	0.32
110_F	149_V	0.617	0.32
67_E	73_I	0.617	0.32
15_T	99_K	0.617	0.32
214_L	399_L	0.617	0.32
94_V	157_S	0.616	0.32
61_K	139_I	0.615	0.32
244_A	327_I	0.615	0.32
490_T	521_Q	0.614	0.32
329_N	341_A	0.614	0.32
32_V	292_G	0.613	0.32
298_V	301_D	0.610	0.32
358_K	416_E	0.609	0.32
290_R	442_S	0.609	0.32
302_E	474_H	0.609	0.32
226_G	454_G	0.608	0.31
162_K	168_D	0.608	0.31
187_I	190_T	0.608	0.31
109_G	374_S	0.607	0.31
474_H	487_N	0.607	0.31
95_V	99_K	0.605	0.31
215_S	331_V	0.604	0.31
476_P	490_T	0.603	0.31
498_K	505_E	0.603	0.31
424_V	447_M	0.603	0.31
437_E	458_D	0.602	0.31
41_T	45_A	0.601	0.31
279_E	286_F	0.600	0.31
38_G	212_D	0.600	0.31
420_D	500_V	0.598	0.31
16_C	21_H	0.598	0.31
370_S	393_C	0.597	0.31
50_T	257_G	0.596	0.31
178_V	203_I	0.596	0.31
59_K	384_T	0.596	0.31
487_N	490_T	0.595	0.31
89_R	168_D	0.595	0.31
320_A	388_T	0.595	0.31
157_S	199_S	0.594	0.30
313_F	360_T	0.593	0.30
137_L	326_M	0.592	0.30
121_I	134_A	0.592	0.30
153_F	204_M	0.592	0.30
257_G	264_F	0.590	0.30
153_F	206_F	0.589	0.30
347_A	513_F	0.589	0.30
430_G	439_M	0.589	0.30
446_A	475_V	0.588	0.30
111_A	138_F	0.588	0.30
482_I	487_N	0.588	0.30
109_G	357_S	0.587	0.30
144_N	148_T	0.586	0.30
263_V	524_G	0.586	0.30
435_T	508_E	0.585	0.30
94_V	184_T	0.585	0.30
366_Y	510_F	0.585	0.30
167_T	170_T	0.582	0.30
137_L	259_S	0.582	0.30
127_F	160_H	0.581	0.30
96_S	100_E	0.580	0.29
263_V	357_S	0.580	0.29
46_V	461_M	0.579	0.29
226_G	450_A	0.578	0.29
76_G	98_L	0.578	0.29
61_K	177_I	0.578	0.29
46_V	121_I	0.578	0.29
274_C	294_V	0.577	0.29
310_D	522_A	0.576	0.29
392_T	403_A	0.576	0.29
363_Q	467_F	0.575	0.29
286_F	515_H	0.575	0.29
428_W	436_G	0.573	0.29
84_E	353_L	0.573	0.29
97_Y	101_R	0.573	0.29
431_G	489_W	0.572	0.29
13_L	21_H	0.572	0.29
288_A	399_L	0.572	0.29
62_F	177_I	0.571	0.29
19_V	182_K	0.571	0.29
125_N	202_S	0.571	0.29
53_Y	199_S	0.570	0.29
324_I	332_T	0.569	0.29
466_I	486_E	0.569	0.29
457_E	461_M	0.569	0.29
106_V	122_T	0.567	0.29
77_P	80_Q	0.566	0.28
481_H	492_K	0.566	0.28
514_A	521_Q	0.566	0.28
376_L	381_R	0.565	0.28
69_T	215_S	0.565	0.28
61_K	174_T	0.565	0.28
401_L	404_H	0.565	0.28
136_Q	274_C	0.565	0.28
87_F	179_S	0.564	0.28
364_A	372_Y	0.564	0.28
106_V	131_N	0.564	0.28
101_R	522_A	0.564	0.28
62_F	174_T	0.563	0.28
385_S	501_Y	0.563	0.28
349_A	375_K	0.562	0.28
501_Y	508_E	0.562	0.28
341_A	461_M	0.562	0.28
73_I	152_P	0.562	0.28
374_S	448_V	0.561	0.28
82_I	88_E	0.561	0.28
104_L	524_G	0.561	0.28
204_M	208_L	0.560	0.28
32_V	193_A	0.559	0.28
127_F	131_N	0.559	0.28
281_K	440_K	0.557	0.28
32_V	212_D	0.557	0.28
321_A	399_L	0.557	0.28
431_G	434_G	0.557	0.28
23_L	31_K	0.556	0.28
67_E	72_K	0.556	0.28
199_S	448_V	0.555	0.28
212_D	484_Q	0.555	0.28
332_T	492_K	0.555	0.28
181_E	294_V	0.555	0.28
339_P	489_W	0.553	0.28
357_S	458_D	0.553	0.28
69_T	174_T	0.553	0.28
276_H	399_L	0.553	0.28
474_H	477_G	0.552	0.28
358_K	457_E	0.552	0.28
143_G	146_K	0.551	0.27
39_I	49_T	0.550	0.27
70_K	167_T	0.550	0.27
19_V	83_S	0.550	0.27
21_H	151_Q	0.550	0.27
172_S	176_I	0.549	0.27
295_L	388_T	0.548	0.27
435_T	498_K	0.548	0.27
350_F	498_K	0.548	0.27
22_N	286_F	0.548	0.27
389_T	397_P	0.547	0.27
284_Q	329_N	0.547	0.27
228_V	338_H	0.547	0.27
41_T	69_T	0.546	0.27
32_V	37_E	0.546	0.27
453_E	519_I	0.546	0.27
110_F	399_L	0.545	0.27
13_L	27_Q	0.544	0.27
38_G	135_R	0.544	0.27
63_I	396_S	0.544	0.27
88_E	147_K	0.542	0.27
125_N	134_A	0.542	0.27
462_I	480_D	0.541	0.27
111_A	204_M	0.541	0.27
132_L	292_G	0.541	0.27
295_L	513_F	0.540	0.27
500_V	521_Q	0.540	0.27
130_H	196_M	0.539	0.27
487_N	491_N	0.537	0.27
69_T	206_F	0.537	0.27
464_D	499_A	0.537	0.27
486_E	491_N	0.537	0.27
225_K	455_K	0.537	0.27
257_G	266_I	0.536	0.26
134_A	200_I	0.536	0.26
281_K	442_S	0.535	0.26
175_F	295_L	0.535	0.26
374_S	384_T	0.534	0.26
70_K	116_K	0.534	0.26
286_F	329_N	0.534	0.26
157_S	449_K	0.533	0.26
104_L	158_A	0.532	0.26
449_K	453_E	0.532	0.26
333_P	399_L	0.532	0.26
161_F	168_D	0.532	0.26
330_I	347_A	0.531	0.26
171_H	419_A	0.529	0.26
126_E	381_R	0.529	0.26
174_T	193_A	0.529	0.26
432_G	482_I	0.529	0.26
366_Y	370_S	0.529	0.26
280_E	442_S	0.529	0.26
36_N	522_A	0.528	0.26
72_K	405_V	0.527	0.26
216_M	232_F	0.527	0.26
327_I	330_I	0.527	0.26
153_F	365_M	0.526	0.26
90_L	168_D	0.526	0.26
92_T	260_D	0.525	0.26
57_S	381_R	0.525	0.26
274_C	321_A	0.525	0.26
440_K	479_P	0.525	0.26
205_N	215_S	0.524	0.26
361_K	396_S	0.524	0.26
432_G	440_K	0.524	0.26
411_G	520_A	0.524	0.26
353_L	469_L	0.524	0.26
182_K	306_E	0.523	0.26
53_Y	374_S	0.523	0.26
171_H	343_V	0.523	0.26
491_N	496_K	0.523	0.26
330_I	333_P	0.522	0.26
213_I	523_G	0.522	0.26
76_G	79_N	0.522	0.26
357_S	447_M	0.521	0.25
132_L	294_V	0.521	0.25
46_V	440_K	0.521	0.25
353_L	471_I	0.521	0.25
158_A	357_S	0.521	0.25
407_A	411_G	0.521	0.25
465_D	470_H	0.520	0.25
153_F	193_A	0.520	0.25
118_R	141_P	0.520	0.25
18_N	260_D	0.520	0.25
178_V	443_Y	0.519	0.25
437_E	490_T	0.519	0.25
22_N	525_P	0.518	0.25
225_K	514_A	0.518	0.25
276_H	306_E	0.517	0.25
414_I	498_K	0.517	0.25
113_A	139_I	0.516	0.25
415_D	519_I	0.516	0.25
292_G	325_H	0.515	0.25
24_S	63_I	0.515	0.25
508_E	519_I	0.514	0.25
203_I	442_S	0.514	0.25
61_K	369_L	0.513	0.25
196_M	399_L	0.513	0.25
87_F	431_G	0.512	0.25
61_K	82_I	0.512	0.25
193_A	343_V	0.512	0.25
259_S	523_G	0.512	0.25
71_N	247_D	0.512	0.25
362_E	523_G	0.512	0.25
62_F	170_T	0.511	0.25
341_A	448_V	0.510	0.25
57_S	60_D	0.509	0.25
106_V	290_R	0.509	0.25
418_G	490_T	0.509	0.25
289_I	293_S	0.509	0.25
61_K	157_S	0.509	0.25
24_S	432_G	0.508	0.25
76_G	80_Q	0.508	0.25
246_A	375_K	0.508	0.25
181_E	260_D	0.508	0.25
289_I	344_F	0.508	0.25
114_D	262_G	0.508	0.25
112_G	128_A	0.508	0.25
138_F	177_I	0.508	0.25
357_S	469_L	0.507	0.25
144_N	147_K	0.506	0.25
118_R	149_V	0.505	0.24
201_F	394_F	0.504	0.24
136_Q	422_F	0.504	0.24
300_V	313_F	0.504	0.24
22_N	523_G	0.504	0.24
210_E	215_S	0.503	0.24
260_D	413_K	0.503	0.24
80_Q	517_D	0.503	0.24
224_E	493_E	0.503	0.24
459_A	475_V	0.503	0.24
156_L	184_T	0.503	0.24
279_E	512_K	0.502	0.24
130_H	160_H	0.501	0.24
109_G	140_R	0.501	0.24
344_F	364_A	0.501	0.24
43_T	289_I	0.501	0.24
429_T	433_Y	0.501	0.24
510_F	516_T	0.500	0.24
204_M	207_L	0.500	0.24

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1j3bA	2	0.9715	100	0.218	Contact Map
1ytmA	1	0.9564	100	0.223	Contact Map
1ii2A	2	0.9715	100	0.225	Contact Map
2olrA	1	0.9867	100	0.236	Contact Map
2zciA	2	0.9165	100	0.474	Contact Map
4r43A	1	0.9184	100	0.477	Contact Map
2fafA	1	0.9317	100	0.501	Contact Map
4gmuA	1	0.9431	100	0.552	Contact Map
2p5tB	1	0.389	94.3	0.973	Contact Map
1xjcA	2	0.2448	94.1	0.973	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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