SYGB - BACSU - GREMLIN Contacts

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SYGB - Glycine--tRNA ligase beta subunit

UniProt:	P54381	Sequences: MSKQDLLLEIGLEEMPARFLNESMVQLGDKLTGWLKEKNITHGEVKLFNTPRRLAVFVKDVAEKQDDIKEEAKGPAKKIALDADGNWTKAAIGFSKGQGANVEDLYIKEVKGIEYVFVQKFQAGQETKSLLPELSGLITSLHFPKNMRWGNEDLRYIRPIKWIVALFGQDVIPFSITNVESGRTTQGHRFLGHEVSIESPSAYEEQLKGQHVIADPSVRKQMIQSQLETMAAENNWSIPVDEDLLDEVNHLVEYPTALYGSFESEFLSIPEEVLVTTMKEHQRYFPVKDKNGDLLPHFITVRNGNSHAIENVARGNEKVLRARLSDASFFYKEDQKLNIDANVKKLENIVFHEELGSLADKVRRVTSIAEKLAVRLQADEDTLKHVKRAAEISKFDLVTHMIYEFPELQGIMGEKYARMLGEDEAVAAAVNEHYMPRSAGGETPSTFTGAVVAMADKLDTIASFFSIGVIPTGSQDPYGLRRQASGIVAILLDRNWGISFEELLTFVQTDKENELLDFFTQRLKYVLNAEQIRHDVIDAVLESSELEPYSALHKAQVLEQKLGAPGFKETAEALGRVISISKKGVRGDIQPDLFENEYEAKLFDAYQTAKQNLQENFSKKDYEAALASLAALKEPIDAYFDHTMVIADNESLKANRLAQMVSLADEIKSFANMNALIVK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	679 (670)
Sequences:	2156 (1529)
Seq/√Len:	59.1

ECOLI - SYGB
BACSU - SYGB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
208_K	218_V	6.022	1.00
388_R	422_E	5.425	1.00
347_E	359_A	4.929	1.00
385_H	423_D	4.672	1.00
621_D	624_A	4.490	1.00
418_R	424_E	4.273	1.00
43_G	60_D	3.732	1.00
366_T	387_K	3.526	1.00
344_K	347_E	3.417	1.00
40_I	127_T	3.404	1.00
175_S	180_E	3.285	1.00
109_E	114_E	3.238	1.00
610_K	662_S	3.115	1.00
444_P	490_I	3.014	1.00
226_Q	257_A	2.911	1.00
183_R	196_S	2.894	1.00
597_E	600_A	2.894	1.00
598_Y	642_H	2.856	1.00
125_Q	129_S	2.824	1.00
389_A	429_A	2.804	1.00
241_D	279_K	2.762	1.00
370_E	387_K	2.736	1.00
328_S	332_K	2.717	1.00
186_Q	194_E	2.699	1.00
31_L	56_V	2.643	1.00
639_Y	659_Q	2.532	1.00
107_I	114_E	2.527	1.00
335_Q	419_M	2.526	1.00
338_N	341_A	2.523	1.00
359_A	363_R	2.511	1.00
6_L	165_A	2.500	1.00
499_S	546_L	2.461	1.00
414_E	418_R	2.399	1.00
8_L	27_L	2.385	1.00
89_K	92_I	2.376	1.00
289_D	293_D	2.354	1.00
224_Q	228_E	2.326	1.00
173_P	180_E	2.324	1.00
48_F	204_E	2.312	1.00
265_E	328_S	2.307	1.00
248_V	285_F	2.301	1.00
199_S	202_A	2.285	1.00
110_V	113_I	2.249	1.00
128_K	170_D	2.238	1.00
4_Q	168_G	2.226	1.00
71_E	108_K	2.225	1.00
166_L	183_R	2.220	1.00
227_L	299_I	2.212	1.00
271_E	288_K	2.197	1.00
126_E	129_S	2.165	1.00
433_H	452_V	2.160	1.00
332_K	335_Q	2.142	1.00
414_E	431_N	2.135	1.00
438_S	441_G	2.120	1.00
91_A	95_S	2.119	1.00
202_A	206_Q	2.116	1.00
67_D	123_A	2.106	1.00
132_P	135_S	2.094	1.00
204_E	218_V	2.073	1.00
92_I	96_K	2.050	1.00
638_A	642_H	2.014	1.00
431_N	435_M	2.007	1.00
220_K	246_D	2.004	1.00
87_W	91_A	2.000	1.00
418_R	427_A	1.995	1.00
95_S	100_A	1.993	1.00
385_H	425_A	1.983	1.00
430_V	433_H	1.981	1.00
633_K	637_D	1.978	1.00
40_I	61_V	1.974	1.00
450_A	494_R	1.974	1.00
46_K	59_K	1.969	1.00
93_G	96_K	1.966	1.00
29_D	33_G	1.964	1.00
497_G	547_E	1.964	1.00
386_V	452_V	1.953	1.00
393_S	433_H	1.936	1.00
505_T	512_E	1.935	1.00
277_T	281_H	1.929	1.00
594_F	600_A	1.926	1.00
342_N	399_T	1.916	1.00
198_E	202_A	1.915	1.00
595_E	647_A	1.885	1.00
204_E	214_A	1.877	1.00
205_E	209_G	1.875	1.00
347_E	363_R	1.873	1.00
453_A	457_K	1.867	1.00
69_K	121_F	1.867	1.00
46_K	215_D	1.866	1.00
76_A	97_G	1.865	1.00
92_I	101_N	1.865	1.00
366_T	391_E	1.862	1.00
64_K	67_D	1.857	1.00
221_Q	225_S	1.841	1.00
343_V	395_F	1.834	1.00
108_K	117_F	1.816	1.00
5_D	201_S	1.814	0.99
224_Q	242_E	1.804	0.99
261_S	297_H	1.792	0.99
100_A	118_V	1.791	0.99
437_R	441_G	1.783	0.99
125_Q	133_E	1.783	0.99
213_I	222_M	1.779	0.99
461_I	515_L	1.770	0.99
67_D	124_G	1.764	0.99
375_R	502_E	1.759	0.99
331_Y	335_Q	1.742	0.99
504_L	515_L	1.741	0.99
192_G	210_Q	1.738	0.99
28_G	32_T	1.737	0.99
71_E	119_Q	1.732	0.99
77_K	107_I	1.728	0.99
603_F	607_Q	1.719	0.99
19_F	144_P	1.717	0.99
550_S	622_Y	1.707	0.99
72_A	97_G	1.706	0.99
127_T	167_F	1.706	0.99
446_T	449_G	1.704	0.99
650_E	654_A	1.703	0.99
403_Y	406_P	1.681	0.99
36_K	42_H	1.669	0.99
263_E	321_R	1.658	0.99
591_P	594_F	1.656	0.99
258_L	300_T	1.653	0.99
236_W	287_V	1.648	0.99
527_L	552_L	1.647	0.99
69_K	119_Q	1.639	0.99
95_S	105_L	1.638	0.99
39_N	68_I	1.637	0.99
236_W	295_L	1.637	0.99
77_K	114_E	1.611	0.99
266_F	325_S	1.593	0.99
81_L	87_W	1.592	0.99
33_G	37_E	1.587	0.99
432_E	449_G	1.583	0.99
257_A	301_V	1.579	0.99
361_K	460_T	1.579	0.99
185_T	195_V	1.574	0.99
432_E	435_M	1.570	0.99
601_K	638_A	1.550	0.98
597_E	601_K	1.546	0.98
457_K	486_G	1.543	0.98
650_E	653_K	1.540	0.98
647_A	652_L	1.533	0.98
335_Q	420_L	1.532	0.98
504_L	512_E	1.528	0.98
64_K	126_E	1.527	0.98
106_Y	119_Q	1.526	0.98
227_L	238_I	1.526	0.98
262_F	267_L	1.518	0.98
11_G	162_W	1.517	0.98
216_P	250_H	1.508	0.98
221_Q	224_Q	1.500	0.98
91_A	116_V	1.499	0.98
234_N	297_H	1.496	0.98
174_F	181_S	1.493	0.98
593_L	655_N	1.492	0.98
101_N	104_D	1.491	0.98
72_A	98_Q	1.485	0.98
454_M	487_I	1.475	0.98
365_V	393_S	1.475	0.98
524_K	538_D	1.474	0.98
372_L	503_L	1.469	0.98
368_I	507_V	1.460	0.98
355_L	463_S	1.445	0.97
450_A	490_I	1.441	0.97
225_S	229_T	1.438	0.97
222_M	225_S	1.434	0.97
5_D	57_F	1.431	0.97
6_L	61_V	1.428	0.97
171_V	183_R	1.423	0.97
646_I	657_L	1.421	0.97
5_D	168_G	1.420	0.97
428_A	446_T	1.420	0.97
63_E	167_F	1.418	0.97
462_A	507_V	1.410	0.97
489_A	493_D	1.407	0.97
532_I	555_A	1.407	0.97
234_N	259_Y	1.406	0.97
550_S	554_K	1.405	0.97
211_H	305_N	1.403	0.97
595_E	652_L	1.402	0.97
223_I	245_L	1.395	0.97
272_E	415_K	1.393	0.97
632_L	635_P	1.390	0.97
369_A	386_V	1.388	0.97
197_I	206_Q	1.384	0.97
274_L	278_M	1.380	0.97
24_M	49_N	1.378	0.97
344_K	359_A	1.377	0.97
229_T	233_E	1.375	0.97
175_S	178_N	1.368	0.96
337_L	341_A	1.357	0.96
164_V	197_I	1.357	0.96
661_V	665_D	1.356	0.96
205_E	208_K	1.354	0.96
86_N	92_I	1.350	0.96
387_K	391_E	1.348	0.96
26_Q	142_H	1.346	0.96
350_V	357_S	1.345	0.96
388_R	426_V	1.325	0.96
534_H	677_I	1.323	0.96
596_N	643_T	1.317	0.96
364_R	459_D	1.316	0.96
422_E	426_V	1.316	0.96
287_V	299_I	1.314	0.96
73_K	115_Y	1.310	0.95
41_T	62_A	1.305	0.95
342_N	420_L	1.298	0.95
388_R	420_L	1.297	0.95
560_Q	623_E	1.296	0.95
10_I	160_I	1.295	0.95
83_A	86_N	1.293	0.95
273_V	401_M	1.288	0.95
271_E	293_D	1.287	0.95
183_R	197_I	1.281	0.95
110_V	117_F	1.280	0.95
488_V	548_P	1.275	0.95
239_P	288_K	1.275	0.95
453_A	486_G	1.274	0.95
360_D	363_R	1.271	0.95
470_I	514_E	1.271	0.95
5_D	59_K	1.269	0.95
133_E	136_G	1.268	0.95
343_V	391_E	1.266	0.94
77_K	85_G	1.264	0.94
340_D	391_E	1.262	0.94
261_S	264_S	1.246	0.94
401_M	412_M	1.238	0.94
15_M	157_I	1.234	0.94
598_Y	638_A	1.232	0.94
238_I	299_I	1.231	0.94
536_V	555_A	1.216	0.93
337_L	345_K	1.213	0.93
125_Q	130_L	1.213	0.93
217_S	220_K	1.211	0.93
386_V	451_V	1.210	0.93
8_L	174_F	1.202	0.93
501_E	513_N	1.197	0.93
372_L	451_V	1.196	0.93
6_L	131_L	1.196	0.93
28_G	47_L	1.195	0.93
195_V	210_Q	1.195	0.93
185_T	207_L	1.194	0.93
185_T	197_I	1.191	0.92
605_A	635_P	1.191	0.92
591_P	607_Q	1.188	0.92
5_D	200_P	1.183	0.92
345_K	398_V	1.183	0.92
220_K	249_N	1.182	0.92
428_A	432_E	1.180	0.92
595_E	649_N	1.175	0.92
91_A	102_V	1.170	0.92
70_E	122_Q	1.169	0.92
639_Y	645_V	1.168	0.92
193_H	210_Q	1.167	0.92
654_A	658_A	1.165	0.92
32_T	36_K	1.164	0.92
8_L	138_I	1.163	0.92
32_T	45_V	1.153	0.91
612_N	628_S	1.151	0.91
339_I	395_F	1.147	0.91
432_E	446_T	1.146	0.91
222_M	226_Q	1.143	0.91
12_L	156_Y	1.142	0.91
538_D	675_A	1.139	0.91
165_A	174_F	1.137	0.91
605_A	609_A	1.136	0.91
184_T	194_E	1.129	0.90
611_Q	615_E	1.129	0.90
184_T	196_S	1.125	0.90
230_M	259_Y	1.123	0.90
600_A	604_D	1.113	0.90
333_E	336_K	1.111	0.90
337_L	342_N	1.110	0.90
278_M	286_P	1.110	0.90
358_L	361_K	1.110	0.90
491_L	496_W	1.109	0.89
385_H	448_T	1.107	0.89
208_K	213_I	1.106	0.89
266_F	277_T	1.106	0.89
8_L	163_I	1.101	0.89
464_F	469_V	1.092	0.89
338_N	420_L	1.092	0.89
630_A	633_K	1.091	0.89
278_M	284_Y	1.087	0.89
230_M	257_A	1.087	0.89
362_V	366_T	1.086	0.88
278_M	320_L	1.084	0.88
98_Q	120_K	1.083	0.88
40_I	58_V	1.083	0.88
605_A	608_T	1.082	0.88
272_E	411_I	1.078	0.88
487_I	519_F	1.072	0.88
342_N	398_V	1.072	0.88
198_E	206_Q	1.068	0.88
261_S	317_E	1.066	0.88
606_Y	663_L	1.066	0.88
102_V	105_L	1.059	0.87
443_T	490_I	1.053	0.87
589_I	594_F	1.052	0.87
202_A	205_E	1.049	0.87
24_M	47_L	1.049	0.87
392_I	422_E	1.049	0.87
42_H	58_V	1.046	0.87
424_E	428_A	1.044	0.86
230_M	233_E	1.044	0.86
339_I	392_I	1.041	0.86
604_D	608_T	1.040	0.86
371_K	506_F	1.038	0.86
591_P	604_D	1.037	0.86
504_L	516_L	1.036	0.86
365_V	390_A	1.036	0.86
530_E	556_Q	1.029	0.86
458_L	504_L	1.026	0.85
228_E	232_A	1.024	0.85
21_N	250_H	1.020	0.85
284_Y	316_N	1.018	0.85
30_K	141_L	1.018	0.85
443_T	493_D	1.018	0.85
68_I	122_Q	1.016	0.85
55_A	203_Y	1.016	0.85
55_A	214_A	1.014	0.85
268_S	332_K	1.013	0.85
247_E	283_R	1.013	0.85
24_M	216_P	1.013	0.85
269_I	273_V	1.012	0.85
25_V	29_D	1.010	0.85
593_L	649_N	1.008	0.84
389_A	452_V	1.007	0.84
648_D	653_K	1.006	0.84
57_F	204_E	1.005	0.84
594_F	655_N	1.004	0.84
162_W	186_Q	1.003	0.84
197_I	202_A	1.000	0.84
366_T	390_A	0.991	0.83
258_L	313_A	0.991	0.83
610_K	614_Q	0.991	0.83
73_K	110_V	0.990	0.83
462_A	508_Q	0.989	0.83
65_Q	127_T	0.987	0.83
365_V	452_V	0.982	0.83
89_K	97_G	0.980	0.83
527_L	555_A	0.978	0.83
73_K	76_A	0.971	0.82
447_F	451_V	0.971	0.82
4_Q	170_D	0.969	0.82
413_G	430_V	0.968	0.82
462_A	515_L	0.967	0.82
74_G	94_F	0.966	0.82
265_E	325_S	0.966	0.82
135_S	174_F	0.966	0.82
417_A	427_A	0.964	0.82
39_N	122_Q	0.962	0.82
302_R	312_V	0.961	0.81
258_L	301_V	0.961	0.81
432_E	445_S	0.961	0.81
300_T	316_N	0.959	0.81
226_Q	229_T	0.958	0.81
501_E	546_L	0.957	0.81
217_S	221_Q	0.957	0.81
188_H	212_V	0.957	0.81
361_K	365_V	0.954	0.81
447_F	450_A	0.952	0.81
206_Q	210_Q	0.951	0.81
23_S	54_L	0.947	0.81
354_E	469_V	0.946	0.80
435_M	449_G	0.945	0.80
48_F	214_A	0.944	0.80
429_A	452_V	0.944	0.80
195_V	207_L	0.943	0.80
21_N	25_V	0.940	0.80
343_V	359_A	0.938	0.80
359_A	391_E	0.938	0.80
257_A	299_I	0.936	0.80
135_S	139_T	0.935	0.80
431_N	437_R	0.933	0.80
362_V	390_A	0.933	0.80
109_E	112_G	0.933	0.80
90_A	93_G	0.932	0.79
401_M	416_Y	0.931	0.79
608_T	612_N	0.927	0.79
409_Q	434_Y	0.925	0.79
536_V	676_L	0.925	0.79
578_I	664_A	0.924	0.79
590_Q	593_L	0.923	0.79
215_D	218_V	0.922	0.79
613_L	666_E	0.919	0.78
100_A	104_D	0.919	0.78
376_L	451_V	0.919	0.78
230_M	234_N	0.918	0.78
88_T	92_I	0.918	0.78
370_E	391_E	0.916	0.78
536_V	562_L	0.916	0.78
4_Q	63_E	0.915	0.78
75_P	94_F	0.915	0.78
216_P	249_N	0.914	0.78
589_I	603_F	0.912	0.78
139_T	154_L	0.911	0.78
533_R	559_E	0.907	0.78
261_S	313_A	0.905	0.77
428_A	445_S	0.904	0.77
535_D	562_L	0.898	0.77
616_N	624_A	0.898	0.77
589_I	658_A	0.897	0.77
206_Q	209_G	0.897	0.77
21_N	246_D	0.896	0.77
91_A	105_L	0.895	0.77
25_V	28_G	0.895	0.77
425_A	446_T	0.891	0.76
552_L	556_Q	0.888	0.76
388_R	392_I	0.887	0.76
27_L	31_L	0.886	0.76
458_L	507_V	0.886	0.76
628_S	631_A	0.886	0.76
89_K	96_K	0.884	0.76
72_A	76_A	0.883	0.76
418_R	428_A	0.882	0.76
339_I	420_L	0.880	0.75
22_E	26_Q	0.874	0.75
594_F	652_L	0.874	0.75
369_A	452_V	0.873	0.75
49_N	216_P	0.873	0.75
425_A	448_T	0.870	0.75
48_F	55_A	0.867	0.74
399_T	420_L	0.867	0.74
20_L	250_H	0.865	0.74
166_L	171_V	0.864	0.74
310_E	313_A	0.861	0.74
501_E	516_L	0.859	0.74
76_A	115_Y	0.858	0.74
526_V	530_E	0.858	0.74
213_I	254_Y	0.857	0.73
347_E	360_D	0.855	0.73
616_N	621_D	0.855	0.73
85_G	88_T	0.854	0.73
107_I	116_V	0.853	0.73
30_K	140_S	0.853	0.73
414_E	427_A	0.852	0.73
372_L	376_L	0.852	0.73
442_E	445_S	0.851	0.73
508_Q	511_K	0.850	0.73
342_N	345_K	0.850	0.73
46_K	57_F	0.846	0.73
65_Q	124_G	0.846	0.73
352_H	464_F	0.842	0.72
183_R	198_E	0.841	0.72
30_K	34_W	0.841	0.72
280_E	407_E	0.838	0.72
313_A	317_E	0.838	0.72
363_R	366_T	0.837	0.72
587_G	658_A	0.836	0.72
95_S	102_V	0.835	0.72
527_L	551_A	0.832	0.71
237_S	290_K	0.831	0.71
146_N	155_R	0.829	0.71
92_I	102_V	0.829	0.71
77_K	81_L	0.828	0.71
447_F	494_R	0.828	0.71
517_D	544_S	0.828	0.71
154_L	176_I	0.827	0.71
492_L	526_V	0.826	0.71
277_T	320_L	0.823	0.70
231_A	299_I	0.822	0.70
415_K	419_M	0.820	0.70
186_Q	195_V	0.816	0.70
549_Y	553_H	0.814	0.70
465_F	471_P	0.814	0.70
491_L	548_P	0.813	0.69
163_I	179_V	0.812	0.69
172_I	181_S	0.811	0.69
457_K	479_G	0.811	0.69
211_H	254_Y	0.810	0.69
95_S	101_N	0.809	0.69
163_I	181_S	0.807	0.69
240_V	279_K	0.807	0.69
49_N	250_H	0.806	0.69
497_G	620_K	0.804	0.69
64_K	123_A	0.802	0.68
73_K	117_F	0.802	0.68
229_T	604_D	0.799	0.68
169_Q	200_P	0.798	0.68
351_F	459_D	0.796	0.68
165_A	181_S	0.795	0.68
339_I	342_N	0.794	0.68
28_G	45_V	0.789	0.67
160_I	177_T	0.789	0.67
138_I	163_I	0.787	0.67
447_F	496_W	0.787	0.67
590_Q	651_S	0.786	0.67
76_A	93_G	0.785	0.67
26_Q	30_K	0.782	0.66
218_V	221_Q	0.782	0.66
342_N	400_H	0.782	0.66
331_Y	415_K	0.781	0.66
373_A	378_A	0.781	0.66
348_N	357_S	0.780	0.66
197_I	214_A	0.779	0.66
414_E	428_A	0.778	0.66
373_A	386_V	0.778	0.66
89_K	93_G	0.777	0.66
73_K	108_K	0.777	0.66
260_G	320_L	0.776	0.66
131_L	165_A	0.776	0.66
65_Q	130_L	0.775	0.66
368_I	372_L	0.775	0.66
436_P	457_K	0.773	0.66
561_K	670_F	0.772	0.65
365_V	460_T	0.769	0.65
74_G	93_G	0.767	0.65
458_L	503_L	0.767	0.65
533_R	562_L	0.766	0.65
25_V	47_L	0.765	0.65
105_L	118_V	0.765	0.65
560_Q	563_G	0.765	0.65
213_I	218_V	0.764	0.65
495_N	553_H	0.764	0.65
197_I	200_P	0.764	0.65
223_I	316_N	0.764	0.65
601_K	605_A	0.763	0.65
128_K	167_F	0.760	0.64
42_H	45_V	0.759	0.64
191_L	211_H	0.759	0.64
246_D	249_N	0.758	0.64
277_T	286_P	0.757	0.64
501_E	512_E	0.757	0.64
274_L	277_T	0.756	0.64
30_K	137_L	0.756	0.64
7_L	203_Y	0.755	0.64
488_V	526_V	0.754	0.64
492_L	530_E	0.754	0.64
561_K	626_L	0.753	0.64
151_N	181_S	0.751	0.63
440_G	489_A	0.750	0.63
262_F	296_P	0.750	0.63
168_G	201_S	0.749	0.63
164_V	182_G	0.748	0.63
435_M	442_E	0.746	0.63
569_E	633_K	0.746	0.63
609_A	628_S	0.744	0.63
428_A	431_N	0.744	0.63
277_T	280_E	0.743	0.62
274_L	324_L	0.742	0.62
81_L	107_I	0.741	0.62
57_F	199_S	0.739	0.62
87_W	102_V	0.739	0.62
284_Y	320_L	0.739	0.62
208_K	222_M	0.738	0.62
174_F	220_K	0.737	0.62
536_V	559_E	0.736	0.62
460_T	464_F	0.734	0.62
488_V	519_F	0.733	0.61
502_E	506_F	0.733	0.61
85_G	91_A	0.733	0.61
341_A	344_K	0.731	0.61
502_E	505_T	0.729	0.61
277_T	327_A	0.729	0.61
333_E	400_H	0.727	0.61
143_F	157_I	0.725	0.61
376_L	498_I	0.725	0.61
62_A	127_T	0.725	0.61
231_A	287_V	0.725	0.61
593_L	651_S	0.722	0.60
342_N	395_F	0.722	0.60
108_K	115_Y	0.721	0.60
162_W	185_T	0.721	0.60
212_V	254_Y	0.720	0.60
220_K	242_E	0.719	0.60
80_A	116_V	0.719	0.60
542_E	675_A	0.719	0.60
554_K	622_Y	0.718	0.60
361_K	459_D	0.717	0.60
81_L	91_A	0.717	0.60
164_V	185_T	0.716	0.60
75_P	93_G	0.715	0.60
138_I	176_I	0.714	0.59
368_I	506_F	0.711	0.59
239_P	286_P	0.710	0.59
256_T	302_R	0.710	0.59
171_V	182_G	0.707	0.59
411_I	431_N	0.706	0.59
614_Q	618_S	0.704	0.58
33_G	36_K	0.703	0.58
185_T	206_Q	0.703	0.58
440_G	443_T	0.702	0.58
135_S	175_S	0.701	0.58
264_S	296_P	0.701	0.58
562_L	567_F	0.700	0.58
77_K	116_V	0.699	0.58
370_E	374_V	0.698	0.58
31_L	134_L	0.695	0.57
31_L	137_L	0.695	0.57
265_E	268_S	0.694	0.57
220_K	224_Q	0.692	0.57
369_A	451_V	0.690	0.57
601_K	604_D	0.690	0.57
557_V	626_L	0.690	0.57
615_E	619_K	0.689	0.57
672_N	675_A	0.688	0.57
44_E	59_K	0.686	0.56
98_Q	118_V	0.685	0.56
574_L	667_I	0.685	0.56
559_E	563_G	0.683	0.56
354_E	467_I	0.682	0.56
72_A	120_K	0.682	0.56
42_H	60_D	0.681	0.56
365_V	456_D	0.681	0.56
268_S	328_S	0.677	0.55
236_W	296_P	0.677	0.55
169_Q	198_E	0.677	0.55
46_K	204_E	0.676	0.55
42_H	62_A	0.675	0.55
21_N	216_P	0.675	0.55
312_V	503_L	0.675	0.55
188_H	191_L	0.675	0.55
453_A	490_I	0.675	0.55
262_F	269_I	0.674	0.55
450_A	496_W	0.674	0.55
314_R	317_E	0.673	0.55
55_A	204_E	0.672	0.55
368_I	386_V	0.671	0.55
400_H	403_Y	0.671	0.55
34_W	136_G	0.671	0.55
10_I	163_I	0.670	0.55
7_L	164_V	0.670	0.55
271_E	275_V	0.670	0.55
169_Q	199_S	0.670	0.55
43_G	61_V	0.669	0.54
371_K	375_R	0.669	0.54
70_E	120_K	0.669	0.54
623_E	650_E	0.668	0.54
318_K	582_K	0.668	0.54
430_V	452_V	0.668	0.54
617_F	625_A	0.666	0.54
171_V	181_S	0.666	0.54
386_V	448_T	0.662	0.54
492_L	523_L	0.661	0.54
43_G	59_K	0.661	0.54
510_D	514_E	0.661	0.54
221_Q	228_E	0.660	0.54
370_E	381_D	0.659	0.53
577_V	664_A	0.659	0.53
62_A	66_D	0.659	0.53
204_E	208_K	0.659	0.53
598_Y	643_T	0.658	0.53
436_P	444_P	0.656	0.53
295_L	300_T	0.656	0.53
276_T	281_H	0.656	0.53
254_Y	305_N	0.655	0.53
94_F	105_L	0.654	0.53
542_E	672_N	0.654	0.53
231_A	236_W	0.653	0.53
88_T	91_A	0.652	0.53
300_T	313_A	0.652	0.53
229_T	232_A	0.652	0.53
81_L	102_V	0.650	0.52
355_L	360_D	0.649	0.52
390_A	455_A	0.649	0.52
534_H	538_D	0.648	0.52
260_G	281_H	0.648	0.52
164_V	171_V	0.647	0.52
224_Q	231_A	0.645	0.52
128_K	172_I	0.645	0.52
63_E	168_G	0.645	0.52
37_E	136_G	0.643	0.52
275_V	288_K	0.642	0.52
80_A	88_T	0.641	0.51
445_S	449_G	0.641	0.51
172_I	180_E	0.640	0.51
143_F	146_N	0.639	0.51
362_V	368_I	0.639	0.51
495_N	549_Y	0.637	0.51
361_K	667_I	0.637	0.51
283_R	400_H	0.637	0.51
76_A	96_K	0.637	0.51
317_E	321_R	0.636	0.51
256_T	304_G	0.636	0.51
491_L	494_R	0.636	0.51
386_V	390_A	0.635	0.51
191_L	304_G	0.635	0.51
491_L	498_I	0.634	0.51
365_V	369_A	0.634	0.51
57_F	197_I	0.634	0.51
281_H	320_L	0.633	0.50
539_A	671_A	0.632	0.50
200_P	214_A	0.632	0.50
302_R	316_N	0.631	0.50
8_L	165_A	0.631	0.50
248_V	252_V	0.630	0.50
259_Y	297_H	0.630	0.50
134_L	174_F	0.630	0.50
108_K	119_Q	0.628	0.50
218_V	222_M	0.627	0.50
357_S	363_R	0.626	0.50
647_A	650_E	0.625	0.50
392_I	430_V	0.625	0.50
106_Y	478_Y	0.625	0.50
80_A	91_A	0.625	0.50
7_L	207_L	0.625	0.50
591_P	597_E	0.624	0.49
609_A	632_L	0.623	0.49
76_A	85_G	0.623	0.49
308_A	311_N	0.623	0.49
132_P	174_F	0.623	0.49
464_F	478_Y	0.623	0.49
267_L	330_F	0.622	0.49
331_Y	639_Y	0.622	0.49
595_E	600_A	0.621	0.49
4_Q	199_S	0.620	0.49
457_K	490_I	0.620	0.49
338_N	342_N	0.620	0.49
172_I	312_V	0.620	0.49
594_F	603_F	0.620	0.49
284_Y	321_R	0.620	0.49
57_F	200_P	0.619	0.49
337_L	399_T	0.618	0.49
65_Q	125_Q	0.618	0.49
8_L	160_I	0.618	0.49
615_E	618_S	0.617	0.49
500_F	516_L	0.615	0.48
550_S	620_K	0.615	0.48
589_I	655_N	0.615	0.48
6_L	181_S	0.615	0.48
173_P	181_S	0.614	0.48
45_V	58_V	0.614	0.48
279_K	286_P	0.614	0.48
395_F	452_V	0.612	0.48
94_F	162_W	0.612	0.48
312_V	316_N	0.612	0.48
608_T	618_S	0.612	0.48
5_D	169_Q	0.611	0.48
98_Q	130_L	0.611	0.48
443_T	494_R	0.611	0.48
504_L	507_V	0.611	0.48
553_H	556_Q	0.610	0.48
187_G	212_V	0.610	0.48
36_K	41_T	0.609	0.48
74_G	149_W	0.609	0.48
639_Y	660_M	0.609	0.48
553_H	621_D	0.608	0.48
261_S	296_P	0.608	0.48
573_A	636_I	0.608	0.48
629_L	667_I	0.608	0.48
55_A	164_V	0.607	0.48
537_I	551_A	0.606	0.47
577_V	633_K	0.606	0.47
515_L	519_F	0.606	0.47
374_V	506_F	0.605	0.47
6_L	58_V	0.602	0.47
116_V	479_G	0.601	0.47
227_L	257_A	0.601	0.47
100_A	103_E	0.601	0.47
95_S	118_V	0.600	0.47
454_M	458_L	0.600	0.47
619_K	624_A	0.599	0.47
557_V	561_K	0.599	0.47
154_L	177_T	0.598	0.47
162_W	189_R	0.598	0.47
513_N	517_D	0.597	0.46
27_L	54_L	0.597	0.46
535_D	677_I	0.597	0.46
406_P	433_H	0.596	0.46
192_G	279_K	0.596	0.46
409_Q	479_G	0.595	0.46
331_Y	577_V	0.595	0.46
32_T	42_H	0.593	0.46
380_E	608_T	0.592	0.46
623_E	627_A	0.591	0.46
435_M	490_I	0.591	0.46
392_I	395_F	0.590	0.46
357_S	418_R	0.590	0.46
343_V	398_V	0.589	0.46
91_A	99_G	0.589	0.46
488_V	523_L	0.589	0.46
360_D	513_N	0.588	0.45
479_G	633_K	0.587	0.45
126_E	163_I	0.587	0.45
591_P	603_F	0.587	0.45
335_Q	399_T	0.586	0.45
245_L	248_V	0.586	0.45
444_P	456_D	0.586	0.45
388_R	423_D	0.586	0.45
636_I	663_L	0.585	0.45
341_A	420_L	0.585	0.45
417_A	430_V	0.584	0.45
116_V	465_F	0.583	0.45
429_A	448_T	0.583	0.45
485_S	515_L	0.583	0.45
501_E	505_T	0.582	0.45
105_L	116_V	0.580	0.45
573_A	630_A	0.580	0.45
341_A	454_M	0.580	0.45
316_N	474_S	0.580	0.45
240_V	245_L	0.579	0.45
161_K	317_E	0.579	0.45
258_L	316_N	0.578	0.44
240_V	287_V	0.578	0.44
338_N	395_F	0.578	0.44
281_H	408_L	0.578	0.44
335_Q	338_N	0.576	0.44
190_F	304_G	0.576	0.44
4_Q	167_F	0.576	0.44
238_I	348_N	0.576	0.44
260_G	300_T	0.575	0.44
94_F	149_W	0.575	0.44
591_P	600_A	0.574	0.44
164_V	179_V	0.574	0.44
18_R	144_P	0.573	0.44
452_V	487_I	0.573	0.44
44_E	170_D	0.573	0.44
415_K	431_N	0.573	0.44
187_G	190_F	0.572	0.44
596_N	647_A	0.572	0.44
444_P	457_K	0.571	0.44
437_R	489_A	0.571	0.44
433_H	539_A	0.571	0.44
39_N	357_S	0.570	0.44
131_L	134_L	0.570	0.44
227_L	240_V	0.570	0.44
438_S	461_I	0.569	0.43
318_K	342_N	0.568	0.43
19_F	157_I	0.568	0.43
281_H	300_T	0.568	0.43
556_Q	560_Q	0.567	0.43
339_I	344_K	0.567	0.43
548_P	551_A	0.567	0.43
57_F	201_S	0.566	0.43
614_Q	669_S	0.566	0.43
302_R	309_I	0.565	0.43
338_N	399_T	0.564	0.43
55_A	197_I	0.564	0.43
457_K	478_Y	0.564	0.43
289_D	292_G	0.564	0.43
572_E	637_D	0.563	0.43
592_D	618_S	0.561	0.43
528_N	537_I	0.561	0.43
594_F	598_Y	0.561	0.43
612_N	615_E	0.561	0.43
580_I	667_I	0.561	0.43
378_A	451_V	0.560	0.42
239_P	279_K	0.560	0.42
34_W	37_E	0.559	0.42
60_D	168_G	0.559	0.42
19_F	143_F	0.559	0.42
433_H	457_K	0.559	0.42
84_D	88_T	0.557	0.42
602_L	645_V	0.557	0.42
362_V	393_S	0.557	0.42
134_L	266_F	0.557	0.42
207_L	214_A	0.557	0.42
182_G	197_I	0.556	0.42
361_K	483_Q	0.554	0.42
607_Q	610_K	0.554	0.42
357_S	403_Y	0.552	0.42
100_A	181_S	0.552	0.42
130_L	134_L	0.552	0.42
237_S	288_K	0.552	0.42
209_G	291_N	0.551	0.41
21_N	220_K	0.551	0.41
231_A	234_N	0.550	0.41
11_G	95_S	0.549	0.41
450_A	577_V	0.549	0.41
269_I	281_H	0.549	0.41
196_S	612_N	0.549	0.41
349_I	479_G	0.549	0.41
20_L	23_S	0.548	0.41
372_L	458_L	0.548	0.41
287_V	297_H	0.548	0.41
511_K	514_E	0.548	0.41
398_V	449_G	0.547	0.41
185_T	210_Q	0.547	0.41
554_K	606_Y	0.547	0.41
34_W	140_S	0.546	0.41
370_E	386_V	0.546	0.41
283_R	286_P	0.545	0.41
55_A	207_L	0.544	0.41
616_N	628_S	0.544	0.41
195_V	206_Q	0.544	0.41
612_N	631_A	0.543	0.41
295_L	320_L	0.542	0.40
100_A	530_E	0.541	0.40
340_D	344_K	0.541	0.40
180_E	509_T	0.541	0.40
93_G	97_G	0.540	0.40
349_I	357_S	0.539	0.40
340_D	388_R	0.538	0.40
207_L	212_V	0.537	0.40
274_L	283_R	0.537	0.40
111_K	114_E	0.536	0.40
160_I	176_I	0.536	0.40
594_F	604_D	0.536	0.40
92_I	289_D	0.536	0.40
145_K	579_S	0.536	0.40
259_Y	299_I	0.536	0.40
463_S	507_V	0.535	0.40
358_L	452_V	0.534	0.40
368_I	478_Y	0.534	0.40
34_W	38_K	0.533	0.40
19_F	23_S	0.533	0.40
75_P	149_W	0.533	0.40
119_Q	490_I	0.532	0.39
386_V	389_A	0.532	0.39
227_L	287_V	0.532	0.39
251_L	441_G	0.531	0.39
31_L	34_W	0.531	0.39
371_K	458_L	0.530	0.39
224_Q	245_L	0.530	0.39
236_W	259_Y	0.530	0.39
610_K	666_E	0.529	0.39
613_L	625_A	0.529	0.39
113_I	117_F	0.529	0.39
436_P	486_G	0.529	0.39
458_L	652_L	0.528	0.39
4_Q	60_D	0.528	0.39
230_M	236_W	0.528	0.39
190_F	399_T	0.527	0.39
200_P	537_I	0.527	0.39
226_Q	256_T	0.526	0.39
649_N	665_D	0.526	0.39
639_Y	643_T	0.526	0.39
26_Q	29_D	0.526	0.39
94_F	408_L	0.525	0.39
8_L	135_S	0.525	0.39
73_K	113_I	0.524	0.39
102_V	107_I	0.524	0.39
359_A	362_V	0.524	0.39
373_A	377_Q	0.523	0.38
446_T	618_S	0.523	0.38
379_D	385_H	0.523	0.38
523_L	551_A	0.523	0.38
485_S	677_I	0.523	0.38
204_E	215_D	0.523	0.38
61_V	540_V	0.522	0.38
12_L	15_M	0.521	0.38
128_K	197_I	0.521	0.38
585_V	588_D	0.521	0.38
436_P	443_T	0.521	0.38
262_F	294_L	0.521	0.38
191_L	254_Y	0.520	0.38
138_I	517_D	0.520	0.38
279_K	403_Y	0.520	0.38
264_S	268_S	0.520	0.38
10_I	179_V	0.518	0.38
493_D	526_V	0.518	0.38
239_P	275_V	0.518	0.38
15_M	143_F	0.517	0.38
97_G	107_I	0.516	0.38
392_I	399_T	0.516	0.38
575_G	579_S	0.516	0.38
180_E	367_S	0.516	0.38
532_I	559_E	0.515	0.38
93_G	162_W	0.515	0.38
227_L	301_V	0.515	0.38
485_S	488_V	0.514	0.38
146_N	157_I	0.514	0.38
370_E	373_A	0.514	0.38
385_H	426_V	0.514	0.38
86_N	381_D	0.514	0.38
286_P	580_I	0.513	0.37
399_T	636_I	0.513	0.37
135_S	138_I	0.513	0.37
580_I	660_M	0.513	0.37
632_L	663_L	0.513	0.37
395_F	420_L	0.513	0.37
63_E	597_E	0.512	0.37
258_L	309_I	0.511	0.37
381_D	385_H	0.510	0.37
29_D	229_T	0.510	0.37
41_T	66_D	0.510	0.37
94_F	276_T	0.510	0.37
484_A	518_F	0.510	0.37
572_E	633_K	0.509	0.37
15_M	567_F	0.509	0.37
466_S	469_V	0.508	0.37
605_A	632_L	0.508	0.37
28_G	56_V	0.508	0.37
299_I	361_K	0.507	0.37
664_A	668_K	0.507	0.37
594_F	639_Y	0.507	0.37
646_I	666_E	0.506	0.37
491_L	549_Y	0.506	0.37
105_L	472_T	0.506	0.37
145_K	157_I	0.506	0.37
658_A	661_V	0.505	0.37
34_W	134_L	0.504	0.36
286_P	400_H	0.504	0.36
94_F	185_T	0.504	0.36
48_F	57_F	0.504	0.36
415_K	418_R	0.503	0.36
256_T	309_I	0.503	0.36
461_I	519_F	0.503	0.36
584_G	646_I	0.503	0.36
349_I	358_L	0.503	0.36
344_K	366_T	0.502	0.36
584_G	661_V	0.502	0.36
11_G	91_A	0.501	0.36
262_F	285_F	0.501	0.36
433_H	456_D	0.501	0.36
185_T	205_E	0.501	0.36
461_I	663_L	0.501	0.36
135_S	181_S	0.500	0.36
170_D	183_R	0.500	0.36
349_I	353_E	0.500	0.36
492_L	552_L	0.500	0.36
23_S	143_F	0.500	0.36

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ccgA	2	0.2489	96.9	0.971	Contact Map
2o08A	2	0.2474	96.6	0.972	Contact Map
2ogiA	2	0.2592	96.6	0.972	Contact Map
4r8zA	2	0.2622	96.4	0.972	Contact Map
4s1bA	2	0.2563	96.3	0.973	Contact Map
3dtoA	2	0.2504	96.2	0.973	Contact Map
2pjqA	2	0.2828	95	0.975	Contact Map
2pq7A	2	0.2342	95	0.975	Contact Map
2qgsA	2	0.2754	95	0.975	Contact Map
3b57A	2	0.2445	94.9	0.975	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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