GREMLIN Database
SYGB - Glycine--tRNA ligase beta subunit
UniProt: P54381 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 679 (670)
Sequences: 2156 (1529)
Seq/√Len: 59.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
208_K218_V6.0221.00
388_R422_E5.4251.00
347_E359_A4.9291.00
385_H423_D4.6721.00
621_D624_A4.4901.00
418_R424_E4.2731.00
43_G60_D3.7321.00
366_T387_K3.5261.00
344_K347_E3.4171.00
40_I127_T3.4041.00
175_S180_E3.2851.00
109_E114_E3.2381.00
610_K662_S3.1151.00
444_P490_I3.0141.00
226_Q257_A2.9111.00
183_R196_S2.8941.00
597_E600_A2.8941.00
598_Y642_H2.8561.00
125_Q129_S2.8241.00
389_A429_A2.8041.00
241_D279_K2.7621.00
370_E387_K2.7361.00
328_S332_K2.7171.00
186_Q194_E2.6991.00
31_L56_V2.6431.00
639_Y659_Q2.5321.00
107_I114_E2.5271.00
335_Q419_M2.5261.00
338_N341_A2.5231.00
359_A363_R2.5111.00
6_L165_A2.5001.00
499_S546_L2.4611.00
414_E418_R2.3991.00
8_L27_L2.3851.00
89_K92_I2.3761.00
289_D293_D2.3541.00
224_Q228_E2.3261.00
173_P180_E2.3241.00
48_F204_E2.3121.00
265_E328_S2.3071.00
248_V285_F2.3011.00
199_S202_A2.2851.00
110_V113_I2.2491.00
128_K170_D2.2381.00
4_Q168_G2.2261.00
71_E108_K2.2251.00
166_L183_R2.2201.00
227_L299_I2.2121.00
271_E288_K2.1971.00
126_E129_S2.1651.00
433_H452_V2.1601.00
332_K335_Q2.1421.00
414_E431_N2.1351.00
438_S441_G2.1201.00
91_A95_S2.1191.00
202_A206_Q2.1161.00
67_D123_A2.1061.00
132_P135_S2.0941.00
204_E218_V2.0731.00
92_I96_K2.0501.00
638_A642_H2.0141.00
431_N435_M2.0071.00
220_K246_D2.0041.00
87_W91_A2.0001.00
418_R427_A1.9951.00
95_S100_A1.9931.00
385_H425_A1.9831.00
430_V433_H1.9811.00
633_K637_D1.9781.00
40_I61_V1.9741.00
450_A494_R1.9741.00
46_K59_K1.9691.00
93_G96_K1.9661.00
29_D33_G1.9641.00
497_G547_E1.9641.00
386_V452_V1.9531.00
393_S433_H1.9361.00
505_T512_E1.9351.00
277_T281_H1.9291.00
594_F600_A1.9261.00
342_N399_T1.9161.00
198_E202_A1.9151.00
595_E647_A1.8851.00
204_E214_A1.8771.00
205_E209_G1.8751.00
347_E363_R1.8731.00
453_A457_K1.8671.00
69_K121_F1.8671.00
46_K215_D1.8661.00
76_A97_G1.8651.00
92_I101_N1.8651.00
366_T391_E1.8621.00
64_K67_D1.8571.00
221_Q225_S1.8411.00
343_V395_F1.8341.00
108_K117_F1.8161.00
5_D201_S1.8140.99
224_Q242_E1.8040.99
261_S297_H1.7920.99
100_A118_V1.7910.99
437_R441_G1.7830.99
125_Q133_E1.7830.99
213_I222_M1.7790.99
461_I515_L1.7700.99
67_D124_G1.7640.99
375_R502_E1.7590.99
331_Y335_Q1.7420.99
504_L515_L1.7410.99
192_G210_Q1.7380.99
28_G32_T1.7370.99
71_E119_Q1.7320.99
77_K107_I1.7280.99
603_F607_Q1.7190.99
19_F144_P1.7170.99
550_S622_Y1.7070.99
72_A97_G1.7060.99
127_T167_F1.7060.99
446_T449_G1.7040.99
650_E654_A1.7030.99
403_Y406_P1.6810.99
36_K42_H1.6690.99
263_E321_R1.6580.99
591_P594_F1.6560.99
258_L300_T1.6530.99
236_W287_V1.6480.99
527_L552_L1.6470.99
69_K119_Q1.6390.99
95_S105_L1.6380.99
39_N68_I1.6370.99
236_W295_L1.6370.99
77_K114_E1.6110.99
266_F325_S1.5930.99
81_L87_W1.5920.99
33_G37_E1.5870.99
432_E449_G1.5830.99
257_A301_V1.5790.99
361_K460_T1.5790.99
185_T195_V1.5740.99
432_E435_M1.5700.99
601_K638_A1.5500.98
597_E601_K1.5460.98
457_K486_G1.5430.98
650_E653_K1.5400.98
647_A652_L1.5330.98
335_Q420_L1.5320.98
504_L512_E1.5280.98
64_K126_E1.5270.98
106_Y119_Q1.5260.98
227_L238_I1.5260.98
262_F267_L1.5180.98
11_G162_W1.5170.98
216_P250_H1.5080.98
221_Q224_Q1.5000.98
91_A116_V1.4990.98
234_N297_H1.4960.98
174_F181_S1.4930.98
593_L655_N1.4920.98
101_N104_D1.4910.98
72_A98_Q1.4850.98
454_M487_I1.4750.98
365_V393_S1.4750.98
524_K538_D1.4740.98
372_L503_L1.4690.98
368_I507_V1.4600.98
355_L463_S1.4450.97
450_A490_I1.4410.97
225_S229_T1.4380.97
222_M225_S1.4340.97
5_D57_F1.4310.97
6_L61_V1.4280.97
171_V183_R1.4230.97
646_I657_L1.4210.97
5_D168_G1.4200.97
428_A446_T1.4200.97
63_E167_F1.4180.97
462_A507_V1.4100.97
489_A493_D1.4070.97
532_I555_A1.4070.97
234_N259_Y1.4060.97
550_S554_K1.4050.97
211_H305_N1.4030.97
595_E652_L1.4020.97
223_I245_L1.3950.97
272_E415_K1.3930.97
632_L635_P1.3900.97
369_A386_V1.3880.97
197_I206_Q1.3840.97
274_L278_M1.3800.97
24_M49_N1.3780.97
344_K359_A1.3770.97
229_T233_E1.3750.97
175_S178_N1.3680.96
337_L341_A1.3570.96
164_V197_I1.3570.96
661_V665_D1.3560.96
205_E208_K1.3540.96
86_N92_I1.3500.96
387_K391_E1.3480.96
26_Q142_H1.3460.96
350_V357_S1.3450.96
388_R426_V1.3250.96
534_H677_I1.3230.96
596_N643_T1.3170.96
364_R459_D1.3160.96
422_E426_V1.3160.96
287_V299_I1.3140.96
73_K115_Y1.3100.95
41_T62_A1.3050.95
342_N420_L1.2980.95
388_R420_L1.2970.95
560_Q623_E1.2960.95
10_I160_I1.2950.95
83_A86_N1.2930.95
273_V401_M1.2880.95
271_E293_D1.2870.95
183_R197_I1.2810.95
110_V117_F1.2800.95
488_V548_P1.2750.95
239_P288_K1.2750.95
453_A486_G1.2740.95
360_D363_R1.2710.95
470_I514_E1.2710.95
5_D59_K1.2690.95
133_E136_G1.2680.95
343_V391_E1.2660.94
77_K85_G1.2640.94
340_D391_E1.2620.94
261_S264_S1.2460.94
401_M412_M1.2380.94
15_M157_I1.2340.94
598_Y638_A1.2320.94
238_I299_I1.2310.94
536_V555_A1.2160.93
337_L345_K1.2130.93
125_Q130_L1.2130.93
217_S220_K1.2110.93
386_V451_V1.2100.93
8_L174_F1.2020.93
501_E513_N1.1970.93
372_L451_V1.1960.93
6_L131_L1.1960.93
28_G47_L1.1950.93
195_V210_Q1.1950.93
185_T207_L1.1940.93
185_T197_I1.1910.92
605_A635_P1.1910.92
591_P607_Q1.1880.92
5_D200_P1.1830.92
345_K398_V1.1830.92
220_K249_N1.1820.92
428_A432_E1.1800.92
595_E649_N1.1750.92
91_A102_V1.1700.92
70_E122_Q1.1690.92
639_Y645_V1.1680.92
193_H210_Q1.1670.92
654_A658_A1.1650.92
32_T36_K1.1640.92
8_L138_I1.1630.92
32_T45_V1.1530.91
612_N628_S1.1510.91
339_I395_F1.1470.91
432_E446_T1.1460.91
222_M226_Q1.1430.91
12_L156_Y1.1420.91
538_D675_A1.1390.91
165_A174_F1.1370.91
605_A609_A1.1360.91
184_T194_E1.1290.90
611_Q615_E1.1290.90
184_T196_S1.1250.90
230_M259_Y1.1230.90
600_A604_D1.1130.90
333_E336_K1.1110.90
337_L342_N1.1100.90
278_M286_P1.1100.90
358_L361_K1.1100.90
491_L496_W1.1090.89
385_H448_T1.1070.89
208_K213_I1.1060.89
266_F277_T1.1060.89
8_L163_I1.1010.89
464_F469_V1.0920.89
338_N420_L1.0920.89
630_A633_K1.0910.89
278_M284_Y1.0870.89
230_M257_A1.0870.89
362_V366_T1.0860.88
278_M320_L1.0840.88
98_Q120_K1.0830.88
40_I58_V1.0830.88
605_A608_T1.0820.88
272_E411_I1.0780.88
487_I519_F1.0720.88
342_N398_V1.0720.88
198_E206_Q1.0680.88
261_S317_E1.0660.88
606_Y663_L1.0660.88
102_V105_L1.0590.87
443_T490_I1.0530.87
589_I594_F1.0520.87
202_A205_E1.0490.87
24_M47_L1.0490.87
392_I422_E1.0490.87
42_H58_V1.0460.87
424_E428_A1.0440.86
230_M233_E1.0440.86
339_I392_I1.0410.86
604_D608_T1.0400.86
371_K506_F1.0380.86
591_P604_D1.0370.86
504_L516_L1.0360.86
365_V390_A1.0360.86
530_E556_Q1.0290.86
458_L504_L1.0260.85
228_E232_A1.0240.85
21_N250_H1.0200.85
284_Y316_N1.0180.85
30_K141_L1.0180.85
443_T493_D1.0180.85
68_I122_Q1.0160.85
55_A203_Y1.0160.85
55_A214_A1.0140.85
268_S332_K1.0130.85
247_E283_R1.0130.85
24_M216_P1.0130.85
269_I273_V1.0120.85
25_V29_D1.0100.85
593_L649_N1.0080.84
389_A452_V1.0070.84
648_D653_K1.0060.84
57_F204_E1.0050.84
594_F655_N1.0040.84
162_W186_Q1.0030.84
197_I202_A1.0000.84
366_T390_A0.9910.83
258_L313_A0.9910.83
610_K614_Q0.9910.83
73_K110_V0.9900.83
462_A508_Q0.9890.83
65_Q127_T0.9870.83
365_V452_V0.9820.83
89_K97_G0.9800.83
527_L555_A0.9780.83
73_K76_A0.9710.82
447_F451_V0.9710.82
4_Q170_D0.9690.82
413_G430_V0.9680.82
462_A515_L0.9670.82
74_G94_F0.9660.82
265_E325_S0.9660.82
135_S174_F0.9660.82
417_A427_A0.9640.82
39_N122_Q0.9620.82
302_R312_V0.9610.81
258_L301_V0.9610.81
432_E445_S0.9610.81
300_T316_N0.9590.81
226_Q229_T0.9580.81
501_E546_L0.9570.81
217_S221_Q0.9570.81
188_H212_V0.9570.81
361_K365_V0.9540.81
447_F450_A0.9520.81
206_Q210_Q0.9510.81
23_S54_L0.9470.81
354_E469_V0.9460.80
435_M449_G0.9450.80
48_F214_A0.9440.80
429_A452_V0.9440.80
195_V207_L0.9430.80
21_N25_V0.9400.80
343_V359_A0.9380.80
359_A391_E0.9380.80
257_A299_I0.9360.80
135_S139_T0.9350.80
431_N437_R0.9330.80
362_V390_A0.9330.80
109_E112_G0.9330.80
90_A93_G0.9320.79
401_M416_Y0.9310.79
608_T612_N0.9270.79
409_Q434_Y0.9250.79
536_V676_L0.9250.79
578_I664_A0.9240.79
590_Q593_L0.9230.79
215_D218_V0.9220.79
613_L666_E0.9190.78
100_A104_D0.9190.78
376_L451_V0.9190.78
230_M234_N0.9180.78
88_T92_I0.9180.78
370_E391_E0.9160.78
536_V562_L0.9160.78
4_Q63_E0.9150.78
75_P94_F0.9150.78
216_P249_N0.9140.78
589_I603_F0.9120.78
139_T154_L0.9110.78
533_R559_E0.9070.78
261_S313_A0.9050.77
428_A445_S0.9040.77
535_D562_L0.8980.77
616_N624_A0.8980.77
589_I658_A0.8970.77
206_Q209_G0.8970.77
21_N246_D0.8960.77
91_A105_L0.8950.77
25_V28_G0.8950.77
425_A446_T0.8910.76
552_L556_Q0.8880.76
388_R392_I0.8870.76
27_L31_L0.8860.76
458_L507_V0.8860.76
628_S631_A0.8860.76
89_K96_K0.8840.76
72_A76_A0.8830.76
418_R428_A0.8820.76
339_I420_L0.8800.75
22_E26_Q0.8740.75
594_F652_L0.8740.75
369_A452_V0.8730.75
49_N216_P0.8730.75
425_A448_T0.8700.75
48_F55_A0.8670.74
399_T420_L0.8670.74
20_L250_H0.8650.74
166_L171_V0.8640.74
310_E313_A0.8610.74
501_E516_L0.8590.74
76_A115_Y0.8580.74
526_V530_E0.8580.74
213_I254_Y0.8570.73
347_E360_D0.8550.73
616_N621_D0.8550.73
85_G88_T0.8540.73
107_I116_V0.8530.73
30_K140_S0.8530.73
414_E427_A0.8520.73
372_L376_L0.8520.73
442_E445_S0.8510.73
508_Q511_K0.8500.73
342_N345_K0.8500.73
46_K57_F0.8460.73
65_Q124_G0.8460.73
352_H464_F0.8420.72
183_R198_E0.8410.72
30_K34_W0.8410.72
280_E407_E0.8380.72
313_A317_E0.8380.72
363_R366_T0.8370.72
587_G658_A0.8360.72
95_S102_V0.8350.72
527_L551_A0.8320.71
237_S290_K0.8310.71
146_N155_R0.8290.71
92_I102_V0.8290.71
77_K81_L0.8280.71
447_F494_R0.8280.71
517_D544_S0.8280.71
154_L176_I0.8270.71
492_L526_V0.8260.71
277_T320_L0.8230.70
231_A299_I0.8220.70
415_K419_M0.8200.70
186_Q195_V0.8160.70
549_Y553_H0.8140.70
465_F471_P0.8140.70
491_L548_P0.8130.69
163_I179_V0.8120.69
172_I181_S0.8110.69
457_K479_G0.8110.69
211_H254_Y0.8100.69
95_S101_N0.8090.69
163_I181_S0.8070.69
240_V279_K0.8070.69
49_N250_H0.8060.69
497_G620_K0.8040.69
64_K123_A0.8020.68
73_K117_F0.8020.68
229_T604_D0.7990.68
169_Q200_P0.7980.68
351_F459_D0.7960.68
165_A181_S0.7950.68
339_I342_N0.7940.68
28_G45_V0.7890.67
160_I177_T0.7890.67
138_I163_I0.7870.67
447_F496_W0.7870.67
590_Q651_S0.7860.67
76_A93_G0.7850.67
26_Q30_K0.7820.66
218_V221_Q0.7820.66
342_N400_H0.7820.66
331_Y415_K0.7810.66
373_A378_A0.7810.66
348_N357_S0.7800.66
197_I214_A0.7790.66
414_E428_A0.7780.66
373_A386_V0.7780.66
89_K93_G0.7770.66
73_K108_K0.7770.66
260_G320_L0.7760.66
131_L165_A0.7760.66
65_Q130_L0.7750.66
368_I372_L0.7750.66
436_P457_K0.7730.66
561_K670_F0.7720.65
365_V460_T0.7690.65
74_G93_G0.7670.65
458_L503_L0.7670.65
533_R562_L0.7660.65
25_V47_L0.7650.65
105_L118_V0.7650.65
560_Q563_G0.7650.65
213_I218_V0.7640.65
495_N553_H0.7640.65
197_I200_P0.7640.65
223_I316_N0.7640.65
601_K605_A0.7630.65
128_K167_F0.7600.64
42_H45_V0.7590.64
191_L211_H0.7590.64
246_D249_N0.7580.64
277_T286_P0.7570.64
501_E512_E0.7570.64
274_L277_T0.7560.64
30_K137_L0.7560.64
7_L203_Y0.7550.64
488_V526_V0.7540.64
492_L530_E0.7540.64
561_K626_L0.7530.64
151_N181_S0.7510.63
440_G489_A0.7500.63
262_F296_P0.7500.63
168_G201_S0.7490.63
164_V182_G0.7480.63
435_M442_E0.7460.63
569_E633_K0.7460.63
609_A628_S0.7440.63
428_A431_N0.7440.63
277_T280_E0.7430.62
274_L324_L0.7420.62
81_L107_I0.7410.62
57_F199_S0.7390.62
87_W102_V0.7390.62
284_Y320_L0.7390.62
208_K222_M0.7380.62
174_F220_K0.7370.62
536_V559_E0.7360.62
460_T464_F0.7340.62
488_V519_F0.7330.61
502_E506_F0.7330.61
85_G91_A0.7330.61
341_A344_K0.7310.61
502_E505_T0.7290.61
277_T327_A0.7290.61
333_E400_H0.7270.61
143_F157_I0.7250.61
376_L498_I0.7250.61
62_A127_T0.7250.61
231_A287_V0.7250.61
593_L651_S0.7220.60
342_N395_F0.7220.60
108_K115_Y0.7210.60
162_W185_T0.7210.60
212_V254_Y0.7200.60
220_K242_E0.7190.60
80_A116_V0.7190.60
542_E675_A0.7190.60
554_K622_Y0.7180.60
361_K459_D0.7170.60
81_L91_A0.7170.60
164_V185_T0.7160.60
75_P93_G0.7150.60
138_I176_I0.7140.59
368_I506_F0.7110.59
239_P286_P0.7100.59
256_T302_R0.7100.59
171_V182_G0.7070.59
411_I431_N0.7060.59
614_Q618_S0.7040.58
33_G36_K0.7030.58
185_T206_Q0.7030.58
440_G443_T0.7020.58
135_S175_S0.7010.58
264_S296_P0.7010.58
562_L567_F0.7000.58
77_K116_V0.6990.58
370_E374_V0.6980.58
31_L134_L0.6950.57
31_L137_L0.6950.57
265_E268_S0.6940.57
220_K224_Q0.6920.57
369_A451_V0.6900.57
601_K604_D0.6900.57
557_V626_L0.6900.57
615_E619_K0.6890.57
672_N675_A0.6880.57
44_E59_K0.6860.56
98_Q118_V0.6850.56
574_L667_I0.6850.56
559_E563_G0.6830.56
354_E467_I0.6820.56
72_A120_K0.6820.56
42_H60_D0.6810.56
365_V456_D0.6810.56
268_S328_S0.6770.55
236_W296_P0.6770.55
169_Q198_E0.6770.55
46_K204_E0.6760.55
42_H62_A0.6750.55
21_N216_P0.6750.55
312_V503_L0.6750.55
188_H191_L0.6750.55
453_A490_I0.6750.55
262_F269_I0.6740.55
450_A496_W0.6740.55
314_R317_E0.6730.55
55_A204_E0.6720.55
368_I386_V0.6710.55
400_H403_Y0.6710.55
34_W136_G0.6710.55
10_I163_I0.6700.55
7_L164_V0.6700.55
271_E275_V0.6700.55
169_Q199_S0.6700.55
43_G61_V0.6690.54
371_K375_R0.6690.54
70_E120_K0.6690.54
623_E650_E0.6680.54
318_K582_K0.6680.54
430_V452_V0.6680.54
617_F625_A0.6660.54
171_V181_S0.6660.54
386_V448_T0.6620.54
492_L523_L0.6610.54
43_G59_K0.6610.54
510_D514_E0.6610.54
221_Q228_E0.6600.54
370_E381_D0.6590.53
577_V664_A0.6590.53
62_A66_D0.6590.53
204_E208_K0.6590.53
598_Y643_T0.6580.53
436_P444_P0.6560.53
295_L300_T0.6560.53
276_T281_H0.6560.53
254_Y305_N0.6550.53
94_F105_L0.6540.53
542_E672_N0.6540.53
231_A236_W0.6530.53
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300_T313_A0.6520.53
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534_H538_D0.6480.52
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63_E168_G0.6450.52
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275_V288_K0.6420.52
80_A88_T0.6410.51
445_S449_G0.6410.51
172_I180_E0.6400.51
143_F146_N0.6390.51
362_V368_I0.6390.51
495_N549_Y0.6370.51
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283_R400_H0.6370.51
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317_E321_R0.6360.51
256_T304_G0.6360.51
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386_V390_A0.6350.51
191_L304_G0.6350.51
491_L498_I0.6340.51
365_V369_A0.6340.51
57_F197_I0.6340.51
281_H320_L0.6330.50
539_A671_A0.6320.50
200_P214_A0.6320.50
302_R316_N0.6310.50
8_L165_A0.6310.50
248_V252_V0.6300.50
259_Y297_H0.6300.50
134_L174_F0.6300.50
108_K119_Q0.6280.50
218_V222_M0.6270.50
357_S363_R0.6260.50
647_A650_E0.6250.50
392_I430_V0.6250.50
106_Y478_Y0.6250.50
80_A91_A0.6250.50
7_L207_L0.6250.50
591_P597_E0.6240.49
609_A632_L0.6230.49
76_A85_G0.6230.49
308_A311_N0.6230.49
132_P174_F0.6230.49
464_F478_Y0.6230.49
267_L330_F0.6220.49
331_Y639_Y0.6220.49
595_E600_A0.6210.49
4_Q199_S0.6200.49
457_K490_I0.6200.49
338_N342_N0.6200.49
172_I312_V0.6200.49
594_F603_F0.6200.49
284_Y321_R0.6200.49
57_F200_P0.6190.49
337_L399_T0.6180.49
65_Q125_Q0.6180.49
8_L160_I0.6180.49
615_E618_S0.6170.49
500_F516_L0.6150.48
550_S620_K0.6150.48
589_I655_N0.6150.48
6_L181_S0.6150.48
173_P181_S0.6140.48
45_V58_V0.6140.48
279_K286_P0.6140.48
395_F452_V0.6120.48
94_F162_W0.6120.48
312_V316_N0.6120.48
608_T618_S0.6120.48
5_D169_Q0.6110.48
98_Q130_L0.6110.48
443_T494_R0.6110.48
504_L507_V0.6110.48
553_H556_Q0.6100.48
187_G212_V0.6100.48
36_K41_T0.6090.48
74_G149_W0.6090.48
639_Y660_M0.6090.48
553_H621_D0.6080.48
261_S296_P0.6080.48
573_A636_I0.6080.48
629_L667_I0.6080.48
55_A164_V0.6070.48
537_I551_A0.6060.47
577_V633_K0.6060.47
515_L519_F0.6060.47
374_V506_F0.6050.47
6_L58_V0.6020.47
116_V479_G0.6010.47
227_L257_A0.6010.47
100_A103_E0.6010.47
95_S118_V0.6000.47
454_M458_L0.6000.47
619_K624_A0.5990.47
557_V561_K0.5990.47
154_L177_T0.5980.47
162_W189_R0.5980.47
513_N517_D0.5970.46
27_L54_L0.5970.46
535_D677_I0.5970.46
406_P433_H0.5960.46
192_G279_K0.5960.46
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331_Y577_V0.5950.46
32_T42_H0.5930.46
380_E608_T0.5920.46
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357_S418_R0.5900.46
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488_V523_L0.5890.46
360_D513_N0.5880.45
479_G633_K0.5870.45
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335_Q399_T0.5860.45
245_L248_V0.5860.45
444_P456_D0.5860.45
388_R423_D0.5860.45
636_I663_L0.5850.45
341_A420_L0.5850.45
417_A430_V0.5840.45
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429_A448_T0.5830.45
485_S515_L0.5830.45
501_E505_T0.5820.45
105_L116_V0.5800.45
573_A630_A0.5800.45
341_A454_M0.5800.45
316_N474_S0.5800.45
240_V245_L0.5790.45
161_K317_E0.5790.45
258_L316_N0.5780.44
240_V287_V0.5780.44
338_N395_F0.5780.44
281_H408_L0.5780.44
335_Q338_N0.5760.44
190_F304_G0.5760.44
4_Q167_F0.5760.44
238_I348_N0.5760.44
260_G300_T0.5750.44
94_F149_W0.5750.44
591_P600_A0.5740.44
164_V179_V0.5740.44
18_R144_P0.5730.44
452_V487_I0.5730.44
44_E170_D0.5730.44
415_K431_N0.5730.44
187_G190_F0.5720.44
596_N647_A0.5720.44
444_P457_K0.5710.44
437_R489_A0.5710.44
433_H539_A0.5710.44
39_N357_S0.5700.44
131_L134_L0.5700.44
227_L240_V0.5700.44
438_S461_I0.5690.43
318_K342_N0.5680.43
19_F157_I0.5680.43
281_H300_T0.5680.43
556_Q560_Q0.5670.43
339_I344_K0.5670.43
548_P551_A0.5670.43
57_F201_S0.5660.43
614_Q669_S0.5660.43
302_R309_I0.5650.43
338_N399_T0.5640.43
55_A197_I0.5640.43
457_K478_Y0.5640.43
289_D292_G0.5640.43
572_E637_D0.5630.43
592_D618_S0.5610.43
528_N537_I0.5610.43
594_F598_Y0.5610.43
612_N615_E0.5610.43
580_I667_I0.5610.43
378_A451_V0.5600.42
239_P279_K0.5600.42
34_W37_E0.5590.42
60_D168_G0.5590.42
19_F143_F0.5590.42
433_H457_K0.5590.42
84_D88_T0.5570.42
602_L645_V0.5570.42
362_V393_S0.5570.42
134_L266_F0.5570.42
207_L214_A0.5570.42
182_G197_I0.5560.42
361_K483_Q0.5540.42
607_Q610_K0.5540.42
357_S403_Y0.5520.42
100_A181_S0.5520.42
130_L134_L0.5520.42
237_S288_K0.5520.42
209_G291_N0.5510.41
21_N220_K0.5510.41
231_A234_N0.5500.41
11_G95_S0.5490.41
450_A577_V0.5490.41
269_I281_H0.5490.41
196_S612_N0.5490.41
349_I479_G0.5490.41
20_L23_S0.5480.41
372_L458_L0.5480.41
287_V297_H0.5480.41
511_K514_E0.5480.41
398_V449_G0.5470.41
185_T210_Q0.5470.41
554_K606_Y0.5470.41
34_W140_S0.5460.41
370_E386_V0.5460.41
283_R286_P0.5450.41
55_A207_L0.5440.41
616_N628_S0.5440.41
195_V206_Q0.5440.41
612_N631_A0.5430.41
295_L320_L0.5420.40
100_A530_E0.5410.40
340_D344_K0.5410.40
180_E509_T0.5410.40
93_G97_G0.5400.40
349_I357_S0.5390.40
340_D388_R0.5380.40
207_L212_V0.5370.40
274_L283_R0.5370.40
111_K114_E0.5360.40
160_I176_I0.5360.40
594_F604_D0.5360.40
92_I289_D0.5360.40
145_K579_S0.5360.40
259_Y299_I0.5360.40
463_S507_V0.5350.40
358_L452_V0.5340.40
368_I478_Y0.5340.40
34_W38_K0.5330.40
19_F23_S0.5330.40
75_P149_W0.5330.40
119_Q490_I0.5320.39
386_V389_A0.5320.39
227_L287_V0.5320.39
251_L441_G0.5310.39
31_L34_W0.5310.39
371_K458_L0.5300.39
224_Q245_L0.5300.39
236_W259_Y0.5300.39
610_K666_E0.5290.39
613_L625_A0.5290.39
113_I117_F0.5290.39
436_P486_G0.5290.39
458_L652_L0.5280.39
4_Q60_D0.5280.39
230_M236_W0.5280.39
190_F399_T0.5270.39
200_P537_I0.5270.39
226_Q256_T0.5260.39
649_N665_D0.5260.39
639_Y643_T0.5260.39
26_Q29_D0.5260.39
94_F408_L0.5250.39
8_L135_S0.5250.39
73_K113_I0.5240.39
102_V107_I0.5240.39
359_A362_V0.5240.39
373_A377_Q0.5230.38
446_T618_S0.5230.38
379_D385_H0.5230.38
523_L551_A0.5230.38
485_S677_I0.5230.38
204_E215_D0.5230.38
61_V540_V0.5220.38
12_L15_M0.5210.38
128_K197_I0.5210.38
585_V588_D0.5210.38
436_P443_T0.5210.38
262_F294_L0.5210.38
191_L254_Y0.5200.38
138_I517_D0.5200.38
279_K403_Y0.5200.38
264_S268_S0.5200.38
10_I179_V0.5180.38
493_D526_V0.5180.38
239_P275_V0.5180.38
15_M143_F0.5170.38
97_G107_I0.5160.38
392_I399_T0.5160.38
575_G579_S0.5160.38
180_E367_S0.5160.38
532_I559_E0.5150.38
93_G162_W0.5150.38
227_L301_V0.5150.38
485_S488_V0.5140.38
146_N157_I0.5140.38
370_E373_A0.5140.38
385_H426_V0.5140.38
86_N381_D0.5140.38
286_P580_I0.5130.37
399_T636_I0.5130.37
135_S138_I0.5130.37
580_I660_M0.5130.37
632_L663_L0.5130.37
395_F420_L0.5130.37
63_E597_E0.5120.37
258_L309_I0.5110.37
381_D385_H0.5100.37
29_D229_T0.5100.37
41_T66_D0.5100.37
94_F276_T0.5100.37
484_A518_F0.5100.37
572_E633_K0.5090.37
15_M567_F0.5090.37
466_S469_V0.5080.37
605_A632_L0.5080.37
28_G56_V0.5080.37
299_I361_K0.5070.37
664_A668_K0.5070.37
594_F639_Y0.5070.37
646_I666_E0.5060.37
491_L549_Y0.5060.37
105_L472_T0.5060.37
145_K157_I0.5060.37
658_A661_V0.5050.37
34_W134_L0.5040.36
286_P400_H0.5040.36
94_F185_T0.5040.36
48_F57_F0.5040.36
415_K418_R0.5030.36
256_T309_I0.5030.36
461_I519_F0.5030.36
584_G646_I0.5030.36
349_I358_L0.5030.36
344_K366_T0.5020.36
584_G661_V0.5020.36
11_G91_A0.5010.36
262_F285_F0.5010.36
433_H456_D0.5010.36
185_T205_E0.5010.36
461_I663_L0.5010.36
135_S181_S0.5000.36
170_D183_R0.5000.36
349_I353_E0.5000.36
492_L552_L0.5000.36
23_S143_F0.5000.36
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ccgA 2 0.2489 96.9 0.971 Contact Map
2o08A 2 0.2474 96.6 0.972 Contact Map
2ogiA 2 0.2592 96.6 0.972 Contact Map
4r8zA 2 0.2622 96.4 0.972 Contact Map
4s1bA 2 0.2563 96.3 0.973 Contact Map
3dtoA 2 0.2504 96.2 0.973 Contact Map
2pjqA 2 0.2828 95 0.975 Contact Map
2pq7A 2 0.2342 95 0.975 Contact Map
2qgsA 2 0.2754 95 0.975 Contact Map
3b57A 2 0.2445 94.9 0.975 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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