GREMLIN Database
XKDT - Phage-like element PBSX protein XkdT
UniProt: P54339 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 348 (323)
Sequences: 2524 (2183)
Seq/√Len: 121.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
69_A163_L4.5751.00
84_R151_L4.0151.00
222_P226_Q3.8621.00
257_K334_E3.7021.00
280_I307_V3.6831.00
158_E166_R3.6221.00
66_D76_R3.5771.00
62_G160_D3.2491.00
331_S334_E3.1911.00
159_G162_S3.0191.00
87_E148_K2.8591.00
86_G100_F2.8531.00
255_V334_E2.8531.00
69_A167_Y2.7791.00
110_T116_I2.7461.00
220_A253_S2.6811.00
233_D243_A2.5681.00
81_K116_I2.5441.00
184_K188_E2.4571.00
298_I336_P2.4531.00
99_R106_Y2.4281.00
6_T9_A2.4251.00
260_E339_G2.4181.00
184_K198_I2.3771.00
86_G115_L2.2661.00
277_K281_E2.2421.00
122_E156_E2.2171.00
330_L336_P2.2091.00
11_M34_L2.1791.00
265_V280_I2.1441.00
315_D327_N2.1371.00
76_R160_D2.1091.00
281_E285_L2.0711.00
132_N147_V1.9811.00
68_R71_E1.9471.00
79_A120_P1.9391.00
88_F100_F1.9261.00
66_D160_D1.9161.00
89_T144_T1.9091.00
263_A307_V1.8971.00
188_E196_A1.8461.00
204_G207_T1.8461.00
199_F211_V1.7971.00
100_F109_Y1.7471.00
108_Q116_I1.7301.00
187_A210_I1.7071.00
82_A124_G1.7051.00
274_D277_K1.6751.00
187_A228_V1.6691.00
304_N316_Y1.6691.00
76_R163_L1.6681.00
301_S304_N1.6671.00
65_L164_R1.6621.00
117_C123_A1.6441.00
82_A125_N1.6311.00
189_E231_Y1.6171.00
117_C124_G1.6151.00
107_F126_A1.6061.00
108_Q118_E1.5651.00
99_R137_D1.5601.00
86_G145_A1.5461.00
209_K252_E1.5461.00
302_Q306_I1.5131.00
186_W231_Y1.4981.00
65_L160_D1.4931.00
225_I253_S1.4891.00
127_N131_R1.4761.00
264_E317_S1.4741.00
283_G310_S1.4701.00
88_F109_Y1.4551.00
169_T188_E1.4501.00
183_Y208_V1.4411.00
14_M38_A1.4351.00
12_E16_N1.4251.00
210_I232_I1.4241.00
11_M35_A1.4201.00
275_E279_E1.4121.00
282_E286_N1.4071.00
13_R40_E1.4011.00
258_E337_K1.4001.00
99_R108_Q1.3991.00
226_Q230_D1.3981.00
105_L124_G1.3761.00
88_F94_I1.3701.00
15_L31_Y1.3561.00
74_I163_L1.3551.00
98_S109_Y1.3511.00
95_P98_S1.3491.00
212_V228_V1.3471.00
258_E339_G1.3271.00
130_G146_I1.3121.00
288_F338_L1.3101.00
133_L147_V1.3011.00
287_F306_I1.2981.00
62_G76_R1.2961.00
31_Y35_A1.2801.00
221_S224_L1.2741.00
79_A157_E1.2731.00
177_S182_H1.2631.00
161_D164_R1.2530.99
310_S313_V1.2410.99
211_V252_E1.2360.99
190_V228_V1.2290.99
115_L151_L1.2210.99
225_I229_K1.2200.99
102_V105_L1.2190.99
75_E163_L1.2150.99
187_A196_A1.2070.99
231_Y242_Q1.2000.99
220_A225_I1.1990.99
178_A244_P1.1970.99
88_F135_S1.1900.99
278_S281_E1.1870.99
180_K200_P1.1820.99
54_L60_A1.1820.99
214_N224_L1.1810.99
100_F135_S1.1780.99
272_S275_E1.1690.99
8_E12_E1.1680.99
229_K249_V1.1530.99
56_F59_T1.1450.99
267_P276_V1.1440.99
94_I139_I1.1440.99
88_F145_A1.1360.99
125_N154_G1.1340.99
78_A157_E1.1320.99
62_G66_D1.1250.99
187_A190_V1.1220.99
229_K233_D1.1170.99
102_V126_A1.1100.99
260_E340_Q1.0900.99
97_G108_Q1.0860.99
87_E112_D1.0850.99
278_S282_E1.0830.98
210_I251_V1.0820.98
54_L64_F1.0760.98
121_G125_N1.0750.98
184_K197_K1.0640.98
105_L117_C1.0550.98
106_Y118_E1.0500.98
313_V316_Y1.0440.98
330_L334_E1.0430.98
88_F98_S1.0420.98
84_R115_L1.0320.98
201_L207_T1.0290.98
50_T61_Q1.0290.98
176_V179_N1.0250.98
21_D24_T1.0240.98
291_M294_E1.0220.98
101_Y136_L1.0140.98
259_V298_I1.0120.98
23_D28_S1.0100.98
84_R132_N1.0090.98
81_K120_P1.0080.98
87_E146_I1.0070.98
83_V116_I1.0070.98
126_A147_V1.0010.97
14_M34_L0.9990.97
213_T335_I0.9980.97
297_V329_V0.9970.97
276_V312_S0.9970.97
183_Y186_W0.9890.97
224_L227_K0.9880.97
268_E314_S0.9760.97
202_W209_K0.9730.97
7_F11_M0.9700.97
234_P242_Q0.9670.97
50_T54_L0.9640.97
72_A167_Y0.9630.97
57_S68_R0.9620.97
160_D163_L0.9590.97
185_E189_E0.9580.97
176_V182_H0.9570.97
300_L321_I0.9550.97
48_L51_V0.9520.97
98_S142_L0.9470.96
300_L304_N0.9450.96
126_A151_L0.9360.96
146_I150_I0.9320.96
262_S322_N0.9210.96
135_S142_L0.9210.96
58_D67_R0.9200.96
41_L44_S0.9070.96
68_R72_A0.9060.95
100_F147_V0.9030.95
100_F133_L0.8980.95
10_I40_E0.8980.95
10_I13_R0.8910.95
214_N221_S0.8870.95
228_V251_V0.8870.95
85_A149_E0.8830.95
101_Y106_Y0.8830.95
212_V225_I0.8810.95
257_K330_L0.8800.95
42_A46_I0.8780.95
224_L228_V0.8760.95
261_I288_F0.8740.95
132_N145_A0.8680.94
182_H186_W0.8670.94
57_S164_R0.8600.94
187_A232_I0.8580.94
69_A74_I0.8500.94
163_L167_Y0.8500.94
59_T64_F0.8490.94
132_N151_L0.8490.94
54_L61_Q0.8480.94
284_V307_V0.8460.93
299_R315_D0.8450.93
183_Y187_A0.8420.93
19_S24_T0.8420.93
184_K195_K0.8410.93
212_V251_V0.8380.93
209_K333_V0.8370.93
13_R17_S0.8360.93
183_Y247_A0.8360.93
234_P243_A0.8330.93
29_V32_N0.8320.93
74_I167_Y0.8320.93
82_A151_L0.8310.93
57_S167_Y0.8300.93
297_V330_L0.8290.93
115_L298_I0.8270.93
72_A171_V0.8250.93
188_E195_K0.8250.93
111_A114_T0.8180.92
302_Q305_N0.8140.92
81_K119_T0.8130.92
183_Y244_P0.8120.92
186_W189_E0.8110.92
126_A132_N0.8100.92
65_L163_L0.8070.92
243_A249_V0.8070.92
84_R150_I0.8070.92
77_T155_R0.8040.92
135_S139_I0.8020.92
28_S31_Y0.7990.91
41_L45_Y0.7980.91
305_N308_Y0.7960.91
63_E67_R0.7960.91
77_T162_S0.7950.91
6_T45_Y0.7920.91
98_S135_S0.7880.91
45_Y48_L0.7870.91
82_A107_F0.7860.91
11_M15_L0.7840.91
14_M37_A0.7820.91
9_A13_R0.7810.90
207_T250_T0.7800.90
105_L119_T0.7800.90
281_E340_Q0.7780.90
18_I30_I0.7750.90
181_M184_K0.7750.90
285_L339_G0.7730.90
286_N290_K0.7720.90
72_A170_R0.7710.90
147_V150_I0.7700.90
260_E322_N0.7670.90
88_F142_L0.7670.90
301_S308_Y0.7650.90
193_V212_V0.7650.90
203_N209_K0.7640.89
83_V110_T0.7630.89
82_A153_P0.7630.89
99_R136_L0.7620.89
57_S71_E0.7600.89
225_I251_V0.7590.89
192_G215_A0.7570.89
276_V279_E0.7570.89
21_D30_I0.7550.89
300_L327_N0.7530.89
106_Y136_L0.7480.88
27_G31_Y0.7470.88
283_G306_I0.7450.88
220_A224_L0.7420.88
220_A251_V0.7400.88
179_N182_H0.7380.88
285_L289_K0.7350.88
80_T155_R0.7350.88
321_I330_L0.7320.87
93_T112_D0.7320.87
95_P109_Y0.7310.87
202_W207_T0.7260.87
287_F291_M0.7230.87
60_A164_R0.7230.87
11_M14_M0.7210.87
177_S186_W0.7200.87
37_A51_V0.7180.86
102_V132_N0.7170.86
211_V333_V0.7150.86
27_G32_N0.7150.86
263_A280_I0.7140.86
283_G309_N0.7140.86
296_N302_Q0.7100.86
99_R118_E0.7100.86
69_A171_V0.7090.86
252_E333_V0.7070.86
178_A186_W0.7070.86
243_A246_G0.7020.85
206_G225_I0.7020.85
123_A156_E0.7020.85
256_W337_K0.7010.85
209_K250_T0.7010.85
171_V174_E0.7000.85
66_D163_L0.6980.85
273_I277_K0.6960.85
13_R16_N0.6950.85
14_M41_L0.6940.84
221_S228_V0.6930.84
302_Q315_D0.6920.84
225_I254_A0.6910.84
279_E282_E0.6910.84
36_P39_A0.6900.84
10_I45_Y0.6900.84
92_V139_I0.6860.84
268_E271_H0.6850.84
58_D70_A0.6850.84
57_S65_L0.6820.83
190_V231_Y0.6820.83
298_I330_L0.6810.83
194_G213_T0.6790.83
39_A43_K0.6780.83
159_G164_R0.6780.83
52_L56_F0.6770.83
94_I157_E0.6720.83
115_L142_L0.6720.83
267_P277_K0.6720.83
17_S39_A0.6710.82
109_Y115_L0.6700.82
196_A210_I0.6700.82
173_R181_M0.6660.82
26_E35_A0.6660.82
94_I142_L0.6650.82
30_I33_A0.6640.82
109_Y113_G0.6630.82
231_Y234_P0.6540.81
182_H185_E0.6500.80
67_R70_A0.6500.80
167_Y171_V0.6490.80
190_V242_Q0.6440.80
96_V110_T0.6420.80
29_V33_A0.6410.79
77_T166_R0.6400.79
175_A182_H0.6350.79
15_L35_A0.6340.79
276_V310_S0.6310.78
18_I35_A0.6310.78
194_G215_A0.6300.78
287_F290_K0.6270.78
165_E169_T0.6230.78
115_L145_A0.6220.77
107_F151_L0.6210.77
305_N309_N0.6180.77
96_V112_D0.6140.77
226_Q229_K0.6140.77
195_K213_T0.6110.76
47_W51_V0.6100.76
285_L338_L0.6100.76
63_E66_D0.6070.76
49_D53_E0.6040.75
84_R153_P0.6030.75
33_A36_P0.6000.75
58_D168_F0.6000.75
222_P253_S0.6000.75
220_A254_A0.5990.75
204_G248_V0.5990.75
286_N289_K0.5960.74
159_G163_L0.5950.74
65_L167_Y0.5940.74
49_D52_L0.5930.74
323_G334_E0.5930.74
10_I41_L0.5910.74
15_L19_S0.5900.74
9_A46_I0.5900.74
214_N220_A0.5900.74
101_Y104_N0.5890.74
10_I14_M0.5890.74
84_R148_K0.5870.73
219_P256_W0.5850.73
20_A24_T0.5850.73
187_A212_V0.5850.73
135_S145_A0.5830.73
98_S139_I0.5830.73
81_K110_T0.5830.73
32_N35_A0.5820.73
202_W250_T0.5810.73
23_D29_V0.5800.72
17_S40_E0.5790.72
204_G209_K0.5790.72
56_F167_Y0.5780.72
76_R157_E0.5770.72
287_F303_I0.5740.72
190_V227_K0.5740.72
15_L24_T0.5710.71
212_V224_L0.5710.71
77_T158_E0.5710.71
51_V55_V0.5700.71
187_A198_I0.5700.71
203_N207_T0.5690.71
78_A301_S0.5690.71
125_N153_P0.5690.71
325_S329_V0.5690.71
195_K294_E0.5670.71
17_S20_A0.5670.71
301_S316_Y0.5660.71
283_G286_N0.5660.71
186_W232_I0.5660.71
259_V336_P0.5650.70
310_S316_Y0.5650.70
56_F60_A0.5650.70
298_I327_N0.5630.70
7_F39_A0.5620.70
119_T124_G0.5600.70
119_T123_A0.5590.70
6_T22_I0.5590.70
302_Q309_N0.5580.70
280_I283_G0.5570.69
181_M185_E0.5560.69
81_K118_E0.5560.69
299_R327_N0.5540.69
200_P206_G0.5540.69
86_G132_N0.5530.69
170_R175_A0.5520.69
337_K340_Q0.5510.69
52_L55_V0.5510.69
289_K293_F0.5500.68
265_V313_V0.5500.68
193_V196_A0.5480.68
213_T254_A0.5470.68
83_V152_I0.5450.68
102_V147_V0.5440.68
56_F67_R0.5430.67
229_K251_V0.5400.67
60_A65_L0.5390.67
331_S337_K0.5370.67
212_V220_A0.5360.66
82_A121_G0.5360.66
86_G147_V0.5360.66
60_A69_A0.5340.66
304_N308_Y0.5330.66
24_T31_Y0.5320.66
284_V308_Y0.5310.66
27_G35_A0.5300.66
89_T146_I0.5290.65
112_D144_T0.5290.65
40_E43_K0.5280.65
29_V56_F0.5250.65
232_I322_N0.5230.65
51_V140_P0.5190.64
23_D30_I0.5190.64
271_H276_V0.5170.64
70_A76_R0.5160.64
109_Y151_L0.5160.64
223_I227_K0.5160.64
84_R109_Y0.5150.63
203_N212_V0.5150.63
172_R181_M0.5150.63
225_I228_V0.5140.63
304_N307_V0.5140.63
162_S165_E0.5140.63
163_L166_R0.5130.63
33_A37_A0.5130.63
164_R168_F0.5110.63
44_S47_W0.5110.63
101_Y141_G0.5110.63
57_S177_S0.5090.63
12_E309_N0.5090.63
12_E15_L0.5090.63
175_A242_Q0.5080.62
107_F147_V0.5080.62
267_P270_N0.5080.62
50_T53_E0.5070.62
147_V151_L0.5060.62
85_A112_D0.5060.62
269_I329_V0.5050.62
255_V331_S0.5030.62
198_I232_I0.5030.62
308_Y316_Y0.5030.62
28_S59_T0.5030.62
76_R166_R0.5030.62
127_N150_I0.5020.61
23_D48_L0.5010.61
100_F151_L0.5000.61
42_A45_Y0.5000.61
78_A81_K0.5000.61
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3h2tA 2 0.4511 98.2 0.873 Contact Map
3laxA 1 0.2845 52.2 0.949 Contact Map
2y27A 2 0.7155 23.8 0.958 Contact Map
1mdbA 1 0.7184 12.1 0.963 Contact Map
2y4oA 2 0.7126 10.5 0.964 Contact Map
4rvnA 3 0.7098 8.1 0.966 Contact Map
3zieA 2 0.2126 8 0.966 Contact Map
3p04A 2 0.1868 7.2 0.966 Contact Map
2qz7A 1 0.2184 6.7 0.967 Contact Map
4q2lA 1 0.1839 6.6 0.967 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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