GREMLIN Database
XKDQ - Phage-like element PBSX protein XkdQ
UniProt: P54336 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 325 (297)
Sequences: 368 (320)
Seq/√Len: 18.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
97_Y114_D5.9491.00
275_V296_V5.2321.00
203_R220_K4.6991.00
63_E66_R3.8611.00
104_A148_L3.7221.00
157_R172_A3.7201.00
94_Q233_Y3.2050.99
247_Q251_D3.0870.99
271_G308_H3.0760.99
105_D122_I2.9480.99
71_A194_S2.9210.99
33_I57_F2.8270.98
115_F140_L2.8070.98
95_D205_V2.7720.98
99_F107_I2.7670.98
70_F88_Q2.5400.97
118_P167_K2.5180.97
95_D143_I2.4850.96
24_G299_D2.4620.96
224_G258_K2.4300.96
123_A175_D2.3930.96
107_I147_A2.3610.95
24_G31_R2.3360.95
220_K225_L2.3140.95
36_T80_A2.2140.93
94_Q139_T2.1090.91
112_A168_L2.0780.91
125_T151_T2.0650.91
162_Y279_L1.9600.88
205_V232_Q1.9510.88
93_N235_E1.9320.87
20_V57_F1.9070.87
104_A129_I1.8650.85
285_I288_A1.8620.85
99_F110_R1.8560.85
106_Q128_T1.8430.85
51_E195_T1.8390.84
203_R225_L1.8120.84
209_Q213_K1.8030.83
34_E290_I1.7660.82
75_D190_G1.7420.81
151_T170_L1.7330.81
49_V69_V1.7230.80
207_R236_T1.7230.80
35_A55_V1.7010.79
115_F230_V1.6970.79
182_L188_I1.6710.78
105_D124_N1.6670.78
203_R230_V1.6640.78
199_D261_K1.6640.78
69_V81_F1.6460.77
117_I168_L1.6330.76
14_E69_V1.6200.76
269_A310_M1.6000.75
191_Y285_I1.5970.75
102_Q110_R1.5830.74
21_S302_E1.5720.74
103_R124_N1.5600.73
268_Q311_T1.5490.72
88_Q198_N1.5470.72
183_E186_V1.5420.72
264_L285_I1.5400.72
70_F89_Y1.5310.72
297_D315_V1.5180.71
101_N196_S1.5120.71
105_D125_T1.4820.69
22_L299_D1.4230.66
200_T228_Y1.4210.66
73_T194_S1.4060.65
250_A254_L1.4050.65
124_N151_T1.4010.65
241_I246_L1.3880.64
65_F83_A1.3870.64
111_I140_L1.3770.63
298_T313_D1.3760.63
89_Y278_G1.3740.63
279_L296_V1.3670.63
296_V310_M1.3670.63
105_D126_G1.3560.62
110_R114_D1.3540.62
283_I311_T1.3450.61
97_Y143_I1.3390.61
105_D151_T1.3150.59
103_R216_K1.3140.59
89_Y231_L1.3110.59
183_E187_N1.3100.59
35_A81_F1.3090.59
163_S228_Y1.2880.58
157_R174_P1.2840.58
129_I147_A1.2830.58
194_S263_E1.2670.57
31_R299_D1.2470.55
94_Q137_D1.2370.55
283_I287_E1.2370.55
206_L246_L1.2310.54
102_Q107_I1.2300.54
206_L237_V1.2270.54
140_L143_I1.2270.54
108_I148_L1.2250.54
97_Y140_L1.2200.54
51_E260_V1.2070.53
123_A137_D1.2050.53
84_Y87_L1.2050.53
17_A69_V1.2030.53
23_E300_R1.1960.52
201_A257_K1.1850.51
84_Y310_M1.1810.51
108_I122_I1.1690.50
58_K63_E1.1670.50
23_E32_S1.1640.50
93_N141_Y1.1550.50
72_R250_A1.1550.50
8_K28_Q1.1450.49
255_A305_G1.1440.49
284_S291_K1.1420.49
120_T167_K1.1320.48
70_F197_I1.1260.48
127_H130_K1.1210.47
36_T269_A1.1190.47
170_L205_V1.1160.47
176_P202_T1.1090.47
119_T290_I1.0970.46
177_S293_T1.0970.46
74_P195_T1.0920.46
223_S226_N1.0870.45
141_Y259_G1.0740.45
133_V146_K1.0720.44
89_Y229_G1.0700.44
225_L230_V1.0680.44
191_Y264_L1.0650.44
202_T224_G1.0650.44
16_V35_A1.0630.44
86_M163_S1.0540.43
152_K256_E1.0370.42
144_I148_L1.0250.42
241_I249_R1.0170.41
74_P79_L1.0090.41
37_I51_E1.0090.41
73_T192_Q0.9940.40
63_E165_K0.9860.39
25_H138_T0.9780.39
9_D17_A0.9770.39
35_A88_Q0.9720.38
74_P287_E0.9680.38
206_L233_Y0.9670.38
215_Y218_S0.9630.38
136_N236_T0.9580.38
129_I132_L0.9530.37
166_G197_I0.9510.37
70_F84_Y0.9510.37
138_T175_D0.9500.37
131_S305_G0.9490.37
276_Q299_D0.9470.37
210_K213_K0.9450.37
178_E274_E0.9440.37
139_T142_D0.9420.37
114_D119_T0.9420.37
141_Y145_L0.9400.37
203_R227_K0.9380.36
169_G283_I0.9360.36
59_W303_F0.9310.36
96_M205_V0.9220.35
109_R119_T0.9180.35
84_Y166_G0.9160.35
20_V33_I0.9160.35
150_Q199_D0.9160.35
26_R151_T0.9160.35
99_F132_L0.9120.35
27_Y250_A0.9010.34
127_H154_Q0.9010.34
92_K141_Y0.9000.34
32_S289_G0.8980.34
151_T205_V0.8890.34
277_S299_D0.8850.33
100_S211_D0.8840.33
69_V83_A0.8830.33
221_D224_G0.8770.33
210_K238_T0.8710.33
97_Y111_I0.8680.32
57_F102_Q0.8670.32
250_A312_I0.8670.32
160_Q171_R0.8650.32
31_R141_Y0.8640.32
9_D13_L0.8570.32
104_A262_K0.8460.31
35_A261_K0.8460.31
76_E190_G0.8450.31
93_N140_L0.8380.31
89_Y277_S0.8370.31
269_A309_T0.8370.31
296_V299_D0.8340.31
23_E34_E0.8340.31
107_I143_I0.8320.31
92_K139_T0.8300.30
103_R122_I0.8270.30
155_T303_F0.8270.30
77_H281_V0.8260.30
99_F114_D0.8200.30
70_F87_L0.8180.30
229_G250_A0.8180.30
225_L268_Q0.8150.30
68_I228_Y0.8150.30
211_D298_T0.8150.30
181_V281_V0.8130.30
19_S36_T0.8130.30
93_N115_F0.8080.29
68_I86_M0.8080.29
199_D266_N0.8080.29
200_T206_L0.8070.29
262_K286_P0.8050.29
119_T122_I0.8040.29
189_T267_I0.8040.29
206_L234_T0.7990.29
301_H308_H0.7990.29
93_N246_L0.7980.29
29_A141_Y0.7970.29
229_G278_G0.7970.29
229_G254_L0.7950.29
200_T224_G0.7870.28
80_A101_N0.7850.28
152_K158_H0.7850.28
47_Y55_V0.7840.28
188_I260_V0.7760.28
275_V310_M0.7750.28
159_Y206_L0.7750.28
68_I83_A0.7740.28
34_E82_S0.7710.27
202_T258_K0.7670.27
302_E306_T0.7660.27
106_Q170_L0.7610.27
33_I207_R0.7530.27
68_I186_V0.7510.26
120_T169_G0.7500.26
97_Y281_V0.7480.26
206_L235_E0.7460.26
291_K296_V0.7450.26
149_K209_Q0.7440.26
109_R113_S0.7430.26
236_T283_I0.7420.26
217_A239_D0.7390.26
75_D238_T0.7330.26
17_A114_D0.7330.26
123_A234_T0.7320.25
38_V263_E0.7310.25
271_G299_D0.7310.25
26_R297_D0.7290.25
272_I314_V0.7260.25
189_T311_T0.7200.25
13_L34_E0.7200.25
25_H298_T0.7200.25
217_A228_Y0.7170.25
20_V48_S0.7160.25
105_D148_L0.7130.25
110_R309_T0.7130.25
15_L313_D0.7130.25
203_R218_S0.7130.25
37_I262_K0.7110.25
39_T49_V0.7050.24
204_V207_R0.7040.24
275_V281_V0.7040.24
113_S192_Q0.7010.24
95_D151_T0.6980.24
210_K215_Y0.6960.24
36_T78_T0.6940.24
113_S129_I0.6930.24
22_L283_I0.6910.24
97_Y110_R0.6890.24
201_A233_Y0.6860.23
281_V314_V0.6840.23
171_R176_P0.6840.23
102_Q106_Q0.6830.23
77_H107_I0.6830.23
14_E17_A0.6830.23
49_V72_R0.6810.23
24_G224_G0.6780.23
32_S299_D0.6780.23
17_A238_T0.6760.23
111_I168_L0.6750.23
31_R224_G0.6740.23
25_H106_Q0.6730.23
209_Q214_T0.6710.23
115_F174_P0.6690.23
127_H151_T0.6690.23
129_I154_Q0.6660.22
114_D140_L0.6660.22
303_F308_H0.6640.22
19_S189_T0.6630.22
95_D140_L0.6630.22
13_L182_L0.6580.22
25_H145_L0.6560.22
295_W299_D0.6560.22
198_N272_I0.6540.22
80_A161_L0.6540.22
96_M290_I0.6530.22
84_Y155_T0.6530.22
162_Y170_L0.6490.22
193_Y262_K0.6490.22
189_T309_T0.6480.22
210_K214_T0.6480.22
20_V37_I0.6440.22
30_P162_Y0.6410.21
87_L231_L0.6410.21
297_D313_D0.6400.21
254_L263_E0.6390.21
219_A250_A0.6370.21
50_S53_D0.6370.21
55_V254_L0.6360.21
80_A192_Q0.6360.21
222_S226_N0.6350.21
18_E78_T0.6340.21
275_V279_L0.6310.21
237_V240_D0.6310.21
78_T159_Y0.6300.21
96_M129_I0.6290.21
199_D304_K0.6290.21
21_S34_E0.6270.21
159_Y216_K0.6250.21
149_K226_N0.6230.21
151_T200_T0.6230.21
211_D255_A0.6220.21
98_V131_S0.6210.21
210_K217_A0.6190.21
149_K153_S0.6180.20
38_V62_K0.6140.20
92_K235_E0.6130.20
142_D197_I0.6130.20
24_G228_Y0.6130.20
24_G276_Q0.6130.20
283_I315_V0.6110.20
299_D303_F0.6100.20
25_H33_I0.6090.20
103_R106_Q0.6080.20
195_T260_V0.6080.20
138_T146_K0.6070.20
19_S108_I0.6070.20
266_N269_A0.6050.20
208_R279_L0.6030.20
83_A142_D0.6030.20
10_T75_D0.5990.20
22_L150_Q0.5960.20
187_N313_D0.5960.20
142_D191_Y0.5940.20
192_Q313_D0.5940.20
71_A204_V0.5930.19
142_D162_Y0.5920.19
131_S148_L0.5900.19
10_T179_V0.5900.19
129_I269_A0.5840.19
59_W62_K0.5840.19
98_V190_G0.5830.19
71_A198_N0.5830.19
33_I55_V0.5830.19
188_I191_Y0.5820.19
70_F166_G0.5820.19
106_Q109_R0.5810.19
277_S310_M0.5810.19
83_A144_I0.5810.19
16_V212_N0.5790.19
99_F267_I0.5780.19
126_G151_T0.5780.19
52_G190_G0.5730.19
90_L269_A0.5710.19
203_R226_N0.5690.19
73_T188_I0.5690.19
84_Y130_K0.5680.19
80_A311_T0.5680.19
176_P281_V0.5650.18
37_I49_V0.5650.18
211_D215_Y0.5640.18
102_Q108_I0.5610.18
32_S84_Y0.5610.18
211_D259_G0.5610.18
25_H299_D0.5610.18
263_E304_K0.5580.18
51_E57_F0.5570.18
14_E19_S0.5570.18
268_Q291_K0.5560.18
24_G277_S0.5560.18
109_R122_I0.5500.18
273_P303_F0.5490.18
22_L281_V0.5480.18
53_D227_K0.5480.18
196_S199_D0.5450.18
22_L294_Y0.5450.18
162_Y171_R0.5450.18
176_P308_H0.5430.18
20_V108_I0.5430.18
71_A126_G0.5430.18
22_L35_A0.5430.18
97_Y297_D0.5420.18
117_I123_A0.5420.18
182_L291_K0.5390.17
164_E276_Q0.5360.17
182_L303_F0.5350.17
87_L141_Y0.5340.17
138_T193_Y0.5320.17
36_T212_N0.5320.17
75_D139_T0.5310.17
137_D294_Y0.5310.17
93_N145_L0.5290.17
68_I250_A0.5270.17
37_I260_V0.5270.17
103_R128_T0.5270.17
21_S267_I0.5270.17
13_L77_H0.5260.17
192_Q200_T0.5260.17
16_V29_A0.5250.17
81_F119_T0.5240.17
22_L31_R0.5240.17
72_R287_E0.5220.17
17_A296_V0.5220.17
23_E48_S0.5210.17
163_S201_A0.5200.17
57_F130_K0.5200.17
99_F248_Q0.5190.17
105_D170_L0.5190.17
10_T182_L0.5180.17
188_I204_V0.5160.17
19_S57_F0.5160.17
24_G295_W0.5160.17
233_Y253_R0.5160.17
104_A251_D0.5160.17
143_I207_R0.5150.17
68_I119_T0.5130.17
207_R215_Y0.5130.17
175_D197_I0.5120.16
180_W272_I0.5100.16
202_T272_I0.5090.16
128_T247_Q0.5090.16
109_R116_Q0.5070.16
162_Y169_G0.5070.16
69_V73_T0.5060.16
164_E169_G0.5060.16
278_G301_H0.5060.16
212_N242_N0.5060.16
87_L163_S0.5060.16
55_V144_I0.5050.16
277_S303_F0.5040.16
170_L200_T0.5040.16
240_D296_V0.5040.16
45_T262_K0.5040.16
35_A133_V0.5030.16
99_F260_V0.5030.16
73_T255_A0.5010.16
90_L129_I0.5000.16
96_M139_T0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3d37A 5 0.9262 100 0.663 Contact Map
3cddA 3 0.9477 100 0.665 Contact Map
1wruA 3 0.9354 100 0.673 Contact Map
3gs9A 3 0.8523 99.8 0.774 Contact Map
2p5zX 3 0.7969 99.3 0.851 Contact Map
4mtkA 4 0.9569 99.2 0.854 Contact Map
2e5pA 1 0.2092 35.4 0.963 Contact Map
2m0oA 1 0.2431 35.3 0.963 Contact Map
2eqjA 1 0.2031 31.4 0.964 Contact Map
2e5qA 1 0.1938 24.3 0.966 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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