YQER - BACSU - GREMLIN Contacts

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YQER - Oxygen-independent coproporphyrinogen-III oxidase-like protein YqeR

UniProt:	P54304	Sequences: MKSAYIHIPFCEHICHYCDFNKYFIQSQPVDEYLNALEQEMINTIAKTGQPDLKTIFIGGGTPTSLSEEQLKKLMDMINRVLKPSSDLSEFAVEANPDDLSAEKLKILKEAGVNRLSFGVQTFEDDLLEKIGRVHKQKDVFTSFERAREIGFENISLDLMFGLPGQTLKHLEHSINTALSLDAEHYSVYSLIVEPKTVFYNLMQKGRLHLPPQEQEAEMYEIVMSKMEAHGIHQYEISNFAKAGMESKHNLTYWSNEQYFGFGAGAHGYIGGTRTVNVGPVKHYIDLIAEKGFPYRDTHEVTTEEQIEEEMFLGLRKTAGVSKKRFAEKYGRSLDGLFPSVLKDLAEKGLIHNSESAVYLTHQGKLLGNEVFGAFLGEL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	379 (369)
Sequences:	6834 (4894)
Seq/√Len:	254.8

ECOLI - HEMN YGGW
BACSU - YQER HEMZ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
38_E	77_M	3.874	1.00
176_N	226_K	3.112	1.00
38_E	73_K	2.980	1.00
172_E	222_I	2.810	1.00
182_D	242_K	2.801	1.00
35_N	73_K	2.771	1.00
148_R	184_E	2.723	1.00
136_K	139_D	2.713	1.00
42_I	77_M	2.660	1.00
42_I	81_V	2.481	1.00
361_T	364_G	2.369	1.00
352_H	359_Y	2.367	1.00
36_A	285_I	2.367	1.00
31_D	70_Q	2.328	1.00
84_P	89_S	2.291	1.00
141_F	177_T	2.244	1.00
102_A	149_E	2.233	1.00
179_L	230_H	2.169	1.00
72_K	76_D	2.161	1.00
3_S	252_T	2.091	1.00
116_L	147_A	2.084	1.00
67_S	70_Q	2.073	1.00
302_T	305_E	2.064	1.00
14_I	22_K	2.042	1.00
125_D	137_Q	2.024	1.00
124_E	170_H	2.015	1.00
145_E	149_E	2.012	1.00
32_E	289_A	1.989	1.00
72_K	110_E	1.985	1.00
172_E	226_K	1.975	1.00
280_P	283_H	1.963	1.00
212_P	215_Q	1.948	1.00
120_V	140_V	1.935	1.00
323_K	353_N	1.918	1.00
177_T	180_S	1.909	1.00
171_L	223_V	1.904	1.00
33_Y	264_A	1.891	1.00
123_F	178_A	1.882	1.00
41_M	262_F	1.868	1.00
31_D	73_K	1.849	1.00
34_L	38_E	1.844	1.00
225_S	229_A	1.792	1.00
173_H	177_T	1.767	1.00
138_K	142_T	1.764	1.00
154_N	245_M	1.763	1.00
125_D	138_K	1.754	1.00
6_I	78_I	1.739	1.00
345_L	374_A	1.736	1.00
179_L	226_K	1.721	1.00
142_T	145_E	1.718	1.00
345_L	371_V	1.709	1.00
4_A	53_L	1.704	1.00
343_K	347_E	1.676	1.00
126_D	170_H	1.674	1.00
105_L	147_A	1.666	1.00
226_K	230_H	1.644	1.00
172_E	176_N	1.633	1.00
169_K	172_E	1.622	1.00
188_V	223_V	1.615	1.00
268_G	275_T	1.611	1.00
168_L	222_I	1.603	1.00
346_A	353_N	1.597	1.00
102_A	146_R	1.592	1.00
8_I	66_L	1.581	1.00
93_V	113_V	1.573	1.00
224_M	240_F	1.571	1.00
168_L	218_E	1.556	1.00
141_F	145_E	1.553	1.00
139_D	142_T	1.550	1.00
36_A	289_A	1.548	1.00
127_L	170_H	1.545	1.00
40_E	277_N	1.540	1.00
157_L	178_A	1.523	1.00
37_L	262_F	1.519	1.00
286_D	290_E	1.517	1.00
109_K	152_F	1.514	1.00
173_H	176_N	1.510	1.00
106_K	150_I	1.507	1.00
68_E	107_I	1.499	1.00
39_Q	42_I	1.498	1.00
222_I	225_S	1.497	1.00
175_I	226_K	1.494	1.00
327_A	333_S	1.494	1.00
137_Q	141_F	1.491	1.00
307_I	326_F	1.466	1.00
162_G	216_E	1.465	1.00
282_K	286_D	1.457	1.00
322_S	325_R	1.456	1.00
34_L	74_L	1.449	1.00
41_M	78_I	1.420	1.00
251_L	317_K	1.406	1.00
106_K	110_E	1.405	1.00
124_E	127_L	1.405	1.00
176_N	180_S	1.404	1.00
123_F	177_T	1.395	1.00
323_K	357_A	1.392	1.00
324_K	356_S	1.389	1.00
343_K	346_A	1.387	1.00
72_K	111_A	1.384	1.00
322_S	356_S	1.382	1.00
228_E	362_H	1.374	1.00
107_I	111_A	1.365	1.00
233_H	246_E	1.357	1.00
148_R	182_D	1.356	1.00
125_D	129_E	1.352	1.00
186_Y	227_M	1.346	1.00
199_F	203_M	1.345	1.00
267_H	276_V	1.335	1.00
318_T	365_K	1.332	1.00
167_T	170_H	1.332	1.00
30_V	67_S	1.329	1.00
344_D	374_A	1.329	1.00
184_E	245_M	1.323	1.00
168_L	215_Q	1.322	1.00
276_V	297_D	1.321	1.00
183_A	232_I	1.317	1.00
120_V	123_F	1.301	1.00
124_E	173_H	1.297	1.00
56_I	84_P	1.296	1.00
278_V	287_L	1.295	1.00
52_D	85_S	1.291	1.00
126_D	129_E	1.291	1.00
360_L	368_G	1.279	1.00
43_N	288_I	1.276	1.00
273_T	298_T	1.274	1.00
102_A	106_K	1.270	1.00
34_L	70_Q	1.270	1.00
255_S	319_A	1.267	1.00
127_L	174_S	1.260	1.00
41_M	81_V	1.258	1.00
39_Q	289_A	1.250	1.00
278_V	296_R	1.246	1.00
227_M	232_I	1.246	1.00
233_H	243_A	1.236	1.00
344_D	348_K	1.232	1.00
118_F	147_A	1.228	1.00
21_N	265_G	1.227	1.00
98_D	134_V	1.226	1.00
142_T	146_R	1.215	1.00
261_G	266_A	1.214	1.00
52_D	83_K	1.213	1.00
255_S	317_K	1.209	1.00
78_I	84_P	1.197	1.00
4_A	262_F	1.197	1.00
126_D	165_G	1.194	1.00
144_F	181_L	1.191	1.00
137_Q	177_T	1.189	1.00
30_V	70_Q	1.186	1.00
323_K	335_D	1.174	1.00
252_T	257_E	1.172	1.00
184_E	232_I	1.172	1.00
221_E	366_L	1.171	1.00
311_M	321_V	1.168	1.00
66_L	70_Q	1.167	1.00
310_E	330_Y	1.155	1.00
354_S	359_Y	1.153	1.00
77_M	80_R	1.150	1.00
348_K	363_Q	1.145	1.00
281_V	285_I	1.145	1.00
154_N	184_E	1.140	1.00
190_S	216_E	1.139	1.00
222_I	226_K	1.139	1.00
131_I	163_L	1.137	1.00
215_Q	218_E	1.137	1.00
202_L	207_R	1.136	1.00
153_E	245_M	1.136	1.00
58_I	71_L	1.133	1.00
155_I	184_E	1.133	1.00
146_R	149_E	1.132	1.00
226_K	229_A	1.130	1.00
34_L	66_L	1.127	1.00
38_E	42_I	1.120	1.00
44_T	262_F	1.119	1.00
64_T	108_L	1.115	1.00
225_S	362_H	1.110	1.00
102_A	150_I	1.108	1.00
104_K	108_L	1.096	1.00
310_E	329_K	1.090	1.00
43_N	293_F	1.088	1.00
95_A	100_L	1.088	1.00
93_V	108_L	1.087	1.00
116_L	152_F	1.078	1.00
58_I	74_L	1.078	1.00
148_R	155_I	1.074	1.00
8_I	264_A	1.070	1.00
333_S	336_G	1.068	1.00
105_L	150_I	1.068	1.00
272_G	306_Q	1.064	1.00
68_E	104_K	1.061	1.00
168_L	219_M	1.058	1.00
64_T	95_A	1.057	1.00
34_L	77_M	1.056	1.00
360_L	371_V	1.055	1.00
310_E	314_G	1.042	1.00
325_R	329_K	1.042	1.00
264_A	281_V	1.041	1.00
76_D	80_R	1.041	1.00
246_E	319_A	1.040	1.00
278_V	283_H	1.038	1.00
168_L	172_E	1.036	1.00
147_A	155_I	1.034	1.00
144_F	155_I	1.033	1.00
51_P	258_Q	1.032	1.00
130_K	165_G	1.022	1.00
322_S	357_A	1.019	1.00
122_T	127_L	1.019	1.00
288_I	294_P	1.016	1.00
42_I	80_R	1.015	1.00
198_V	202_L	1.014	1.00
283_H	286_D	1.007	1.00
64_T	93_V	1.006	1.00
31_D	35_N	1.006	1.00
75_M	91_F	0.999	1.00
339_P	343_K	0.995	1.00
4_A	78_I	0.991	1.00
273_T	300_E	0.991	1.00
103_E	107_I	0.990	1.00
314_G	318_T	0.988	1.00
320_G	359_Y	0.982	1.00
54_K	85_S	0.980	1.00
206_G	209_H	0.979	1.00
231_G	243_A	0.976	1.00
101_S	104_K	0.975	1.00
303_T	306_Q	0.975	1.00
35_N	38_E	0.974	1.00
68_E	103_E	0.965	1.00
178_A	186_Y	0.964	1.00
141_F	181_L	0.964	1.00
144_F	148_R	0.963	1.00
258_Q	269_Y	0.957	1.00
144_F	183_A	0.957	1.00
305_E	308_E	0.955	1.00
348_K	374_A	0.953	1.00
299_H	305_E	0.950	1.00
354_S	357_A	0.949	1.00
70_Q	73_K	0.949	1.00
368_G	372_F	0.944	1.00
314_G	321_V	0.944	1.00
40_E	284_Y	0.943	1.00
224_M	234_Q	0.942	1.00
224_M	228_E	0.941	1.00
107_I	110_E	0.934	1.00
71_L	75_M	0.930	1.00
287_L	292_G	0.929	1.00
324_K	328_E	0.909	1.00
23_Y	281_V	0.909	1.00
64_T	99_D	0.906	1.00
198_V	201_N	0.903	1.00
21_N	264_A	0.902	1.00
165_G	209_H	0.900	1.00
109_K	153_E	0.900	1.00
54_K	252_T	0.899	1.00
123_F	174_S	0.899	1.00
148_R	183_A	0.897	1.00
43_N	294_P	0.896	1.00
159_L	174_S	0.892	1.00
344_D	347_E	0.891	1.00
85_S	89_S	0.891	1.00
36_A	39_Q	0.887	1.00
29_P	32_E	0.886	1.00
352_H	361_T	0.882	1.00
71_L	111_A	0.882	1.00
256_N	269_Y	0.881	1.00
54_K	248_K	0.878	1.00
323_K	356_S	0.877	1.00
16_H	199_F	0.876	1.00
251_L	255_S	0.875	1.00
166_Q	219_M	0.872	1.00
312_F	372_F	0.871	1.00
72_K	107_I	0.871	1.00
58_I	93_V	0.869	1.00
103_E	106_K	0.869	1.00
137_Q	140_V	0.866	1.00
79_N	84_P	0.861	0.99
320_G	357_A	0.861	0.99
71_L	93_V	0.860	0.99
77_M	81_V	0.859	0.99
261_G	275_T	0.857	0.99
75_M	78_I	0.856	0.99
79_N	83_K	0.855	0.99
109_K	150_I	0.854	0.99
214_E	218_E	0.852	0.99
75_M	111_A	0.850	0.99
243_A	246_E	0.849	0.99
39_Q	43_N	0.846	0.99
31_D	69_E	0.844	0.99
41_M	77_M	0.840	0.99
92_A	247_S	0.840	0.99
342_L	358_V	0.837	0.99
193_V	203_M	0.834	0.99
114_N	154_N	0.832	0.99
118_F	143_S	0.822	0.99
224_M	362_H	0.822	0.99
179_L	227_M	0.819	0.99
41_M	82_L	0.818	0.99
218_E	221_E	0.818	0.99
182_D	232_I	0.818	0.99
57_F	247_S	0.817	0.99
12_E	99_D	0.812	0.99
283_H	287_L	0.809	0.99
157_L	183_A	0.809	0.99
86_S	89_S	0.806	0.99
353_N	358_V	0.801	0.99
16_H	132_G	0.799	0.99
25_I	30_V	0.797	0.99
67_S	104_K	0.792	0.99
341_V	374_A	0.792	0.99
249_H	253_Y	0.788	0.99
28_Q	32_E	0.787	0.99
159_L	178_A	0.785	0.99
256_N	310_E	0.780	0.99
143_S	146_R	0.779	0.99
3_S	55_T	0.778	0.99
200_Y	203_M	0.777	0.99
215_Q	219_M	0.777	0.99
128_L	135_H	0.776	0.99
303_T	307_I	0.772	0.99
6_I	37_L	0.771	0.99
370_E	373_G	0.770	0.99
161_F	188_V	0.770	0.99
123_F	137_Q	0.770	0.99
95_A	118_F	0.769	0.99
314_G	325_R	0.767	0.99
120_V	157_L	0.760	0.99
159_L	171_L	0.759	0.99
144_F	157_L	0.758	0.99
261_G	268_G	0.756	0.99
369_N	372_F	0.751	0.99
100_L	105_L	0.750	0.99
75_M	79_N	0.746	0.99
34_L	73_K	0.745	0.99
14_I	24_F	0.744	0.99
301_V	306_Q	0.744	0.99
37_L	74_L	0.741	0.98
218_E	222_I	0.739	0.98
36_A	288_I	0.737	0.98
117_S	156_S	0.737	0.98
193_V	199_F	0.732	0.98
53_L	89_S	0.729	0.98
323_K	358_V	0.726	0.98
32_E	36_A	0.725	0.98
69_E	72_K	0.724	0.98
291_K	294_P	0.721	0.98
156_S	247_S	0.720	0.98
363_Q	366_L	0.719	0.98
350_L	367_L	0.718	0.98
45_I	81_V	0.717	0.98
30_V	34_L	0.717	0.98
288_I	291_K	0.717	0.98
91_F	113_V	0.716	0.98
326_F	332_R	0.714	0.98
346_A	351_I	0.712	0.98
285_I	289_A	0.711	0.98
50_Q	83_K	0.709	0.98
32_E	285_I	0.709	0.98
138_K	141_F	0.703	0.98
172_E	225_S	0.702	0.98
325_R	328_E	0.702	0.98
98_D	139_D	0.701	0.98
326_F	334_L	0.700	0.98
350_L	364_G	0.699	0.98
342_L	351_I	0.698	0.98
106_K	149_E	0.697	0.98
217_A	366_L	0.695	0.98
310_E	326_F	0.695	0.98
367_L	370_E	0.694	0.98
56_I	89_S	0.694	0.98
16_H	131_I	0.691	0.98
147_A	152_F	0.691	0.98
161_F	171_L	0.689	0.98
38_E	81_V	0.688	0.98
323_K	334_L	0.688	0.98
338_F	341_V	0.686	0.98
345_L	351_I	0.685	0.97
126_D	130_K	0.683	0.97
195_P	200_Y	0.682	0.97
256_N	306_Q	0.681	0.97
33_Y	37_L	0.681	0.97
171_L	175_I	0.680	0.97
71_L	107_I	0.676	0.97
224_M	365_K	0.676	0.97
64_T	104_K	0.676	0.97
140_V	157_L	0.676	0.97
44_T	47_K	0.675	0.97
163_L	174_S	0.673	0.97
43_N	47_K	0.671	0.97
335_D	353_N	0.671	0.97
12_E	134_V	0.671	0.97
147_A	150_I	0.670	0.97
274_R	309_E	0.668	0.97
199_F	208_L	0.662	0.97
324_K	327_A	0.661	0.97
38_E	74_L	0.660	0.97
84_P	91_F	0.659	0.97
125_D	136_K	0.658	0.97
6_I	262_F	0.658	0.97
127_L	166_Q	0.654	0.97
338_F	375_F	0.654	0.97
44_T	260_F	0.653	0.97
58_I	75_M	0.653	0.97
194_E	197_T	0.652	0.97
58_I	113_V	0.652	0.97
214_E	217_A	0.648	0.97
32_E	35_N	0.648	0.97
54_K	89_S	0.647	0.96
249_H	254_W	0.646	0.96
307_I	330_Y	0.641	0.96
363_Q	367_L	0.641	0.96
308_E	312_F	0.640	0.96
311_M	375_F	0.639	0.96
201_N	205_K	0.638	0.96
76_D	79_N	0.635	0.96
341_V	345_L	0.634	0.96
34_L	67_S	0.633	0.96
304_E	308_E	0.633	0.96
258_Q	270_I	0.632	0.96
343_K	353_N	0.632	0.96
183_A	186_Y	0.631	0.96
71_L	108_L	0.630	0.96
100_L	146_R	0.630	0.96
175_I	222_I	0.629	0.96
169_K	173_H	0.629	0.96
41_M	74_L	0.627	0.96
52_D	86_S	0.626	0.96
327_A	331_G	0.626	0.96
163_L	166_Q	0.625	0.96
146_R	150_I	0.625	0.96
155_I	183_A	0.624	0.96
53_L	82_L	0.622	0.96
69_E	107_I	0.620	0.96
100_L	104_K	0.620	0.96
184_E	242_K	0.620	0.96
220_Y	234_Q	0.619	0.95
3_S	54_K	0.616	0.95
199_F	202_L	0.614	0.95
175_I	179_L	0.613	0.95
234_Q	365_K	0.612	0.95
309_E	313_L	0.612	0.95
73_K	77_M	0.606	0.95
127_L	163_L	0.606	0.95
241_A	246_E	0.606	0.95
342_L	346_A	0.605	0.95
36_A	284_Y	0.604	0.95
105_L	116_L	0.603	0.95
170_H	174_S	0.599	0.95
203_M	208_L	0.598	0.95
13_H	132_G	0.597	0.95
370_E	374_A	0.596	0.94
295_Y	298_T	0.595	0.94
100_L	118_F	0.594	0.94
314_G	317_K	0.593	0.94
108_L	113_V	0.591	0.94
311_M	326_F	0.590	0.94
248_K	251_L	0.590	0.94
68_E	111_A	0.588	0.94
13_H	24_F	0.585	0.94
334_L	338_F	0.581	0.94
265_G	279_G	0.580	0.94
21_N	281_V	0.579	0.94
46_A	81_V	0.579	0.94
156_S	187_S	0.577	0.93
335_D	339_P	0.576	0.93
176_N	230_H	0.574	0.93
76_D	111_A	0.573	0.93
145_E	148_R	0.573	0.93
217_A	221_E	0.572	0.93
223_V	227_M	0.572	0.93
78_I	81_V	0.569	0.93
360_L	364_G	0.569	0.93
4_A	260_F	0.568	0.93
247_S	251_L	0.567	0.93
55_T	248_K	0.566	0.93
310_E	325_R	0.566	0.93
55_T	89_S	0.563	0.93
351_I	358_V	0.562	0.93
105_L	152_F	0.562	0.93
123_F	140_V	0.561	0.92
316_R	372_F	0.560	0.92
264_A	284_Y	0.559	0.92
140_V	144_F	0.557	0.92
176_N	179_L	0.557	0.92
326_F	330_Y	0.557	0.92
118_F	140_V	0.557	0.92
58_I	91_F	0.553	0.92
345_L	348_K	0.551	0.92
221_E	225_S	0.550	0.92
78_I	262_F	0.549	0.92
179_L	182_D	0.549	0.92
315_L	358_V	0.548	0.92
161_F	223_V	0.547	0.92
15_C	18_C	0.547	0.92
303_T	332_R	0.546	0.91
237_I	249_H	0.545	0.91
233_H	318_T	0.543	0.91
250_N	254_W	0.543	0.91
100_L	143_S	0.542	0.91
6_I	41_M	0.540	0.91
42_I	46_A	0.540	0.91
234_Q	366_L	0.538	0.91
301_V	305_E	0.538	0.91
13_H	134_V	0.538	0.91
234_Q	318_T	0.538	0.91
185_H	235_Y	0.536	0.91
20_F	250_N	0.536	0.91
122_T	174_S	0.535	0.91
269_Y	272_G	0.535	0.91
29_P	281_V	0.535	0.91
236_E	249_H	0.533	0.90
53_L	84_P	0.533	0.90
153_E	184_E	0.532	0.90
236_E	250_N	0.532	0.90
276_V	279_G	0.532	0.90
147_A	151_G	0.531	0.90
286_D	289_A	0.531	0.90
254_W	259_Y	0.530	0.90
349_G	363_Q	0.528	0.90
30_V	65_S	0.527	0.90
323_K	327_A	0.525	0.90
239_N	250_N	0.525	0.90
57_F	92_A	0.523	0.90
223_V	226_K	0.522	0.90
179_L	232_I	0.522	0.90
38_E	80_R	0.521	0.89
345_L	350_L	0.521	0.89
135_H	140_V	0.520	0.89
124_E	174_S	0.520	0.89
196_K	200_Y	0.518	0.89
43_N	291_K	0.518	0.89
323_K	354_S	0.517	0.89
228_E	233_H	0.514	0.89
247_S	254_W	0.514	0.89
75_M	107_I	0.511	0.89
327_A	334_L	0.511	0.89
346_A	358_V	0.510	0.88
171_L	219_M	0.509	0.88
95_A	143_S	0.508	0.88
53_L	78_I	0.508	0.88
43_N	292_G	0.507	0.88
40_E	44_T	0.507	0.88
141_F	180_S	0.507	0.88
312_F	369_N	0.506	0.88
19_D	192_I	0.505	0.88
8_I	34_L	0.504	0.88
277_N	284_Y	0.504	0.88
166_Q	170_H	0.504	0.88
220_Y	224_M	0.504	0.88
287_L	290_E	0.504	0.88
56_I	91_F	0.503	0.88
109_K	114_N	0.503	0.88
45_I	82_L	0.502	0.88
235_Y	250_N	0.502	0.88
185_H	238_S	0.502	0.88
44_T	275_T	0.501	0.88
185_H	249_H	0.500	0.88

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1oltA	1	0.9947	100	0.3	Contact Map
1r30A	2	0.7018	100	0.749	Contact Map
4jc0A	1	0.7546	100	0.757	Contact Map
4u0oB	1	0.5884	100	0.757	Contact Map
4wcxA	1	0.8734	99.9	0.766	Contact Map
2qgqA	1	0.6834	99.9	0.767	Contact Map
4r33A	2	0.7678	99.9	0.769	Contact Map
4rtbA	2	0.8391	99.9	0.777	Contact Map
3t7vA	1	0.7388	99.9	0.787	Contact Map
2yx0A	1	0.5963	99.9	0.79	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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