YPNP - BACSU - GREMLIN Contacts

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YPNP - Probable multidrug resistance protein YpnP

UniProt:	P54181	Sequences: MKAYDFTQGNVLKQLVLFSMPIMLGNALQVSFQFIDSLWIGNLLGAKALGAAAVSSTIVLTVLSFILGLNNATLTILSQQKGKDDIKGMASYINAFVVLLTGLSIGFGAAGFFLSELLLRLLKTPESMIPLAETYLQIQFIGILFLFGYNFISTVLRALGDSKTPLRFIAFAVVLNTVLAPLFISVFRMGIAGAAYSTILSQGIAFLYGLFYVIKHKLVPFSIPRMPKWEESALILKLGIPAGLQMMVITGGMMAIMSVVNSYGDHVVSGFGAVQRLDSIITLPAMAAGTAVNSMAGQNIGIGNEKRVGTIARLGVIAVISCMLVIAVMIWVFGKYLIRLFISEPDAVAFGEQYLKWIAFFYPFIGVNFVLNGIVRAAGAMLQVLVLNLISFWVLRYPFTALFSAWLGQKGIGLGIGMSFLFSSCAAFLYYRYGRWKAMKLFTEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	445 (422)
Sequences:	18173 (13632)
Seq/√Len:	663.6

ECOLI - YEEO DINF MDTK WZXE
BACSU - YPNP YISQ NORM YOEA
HALSA - Q9HRF7 Q9HMS7 Q9HN79 Q9HRF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
85_D	88_G	4.601	1.00
145_F	203_G	3.922	1.00
134_T	192_A	3.369	1.00
53_A	272_G	3.146	1.00
338_I	351_G	3.076	1.00
116_E	133_E	3.069	1.00
333_F	336_Y	3.038	1.00
78_S	297_G	2.968	1.00
233_A	237_K	2.857	1.00
116_E	120_R	2.800	1.00
161_D	164_T	2.782	1.00
114_L	117_L	2.780	1.00
304_N	307_R	2.717	1.00
182_L	187_F	2.576	1.00
73_T	96_F	2.544	1.00
138_I	192_A	2.533	1.00
175_L	204_I	2.529	1.00
133_E	137_Q	2.449	1.00
229_W	233_A	2.402	1.00
80_Q	88_G	2.388	1.00
39_W	184_I	2.346	1.00
51_A	131_L	2.276	1.00
39_W	181_P	2.260	1.00
47_K	127_S	2.224	1.00
380_A	430_Y	2.223	1.00
13_K	17_L	2.200	1.00
131_L	134_T	2.195	1.00
125_P	265_D	2.188	1.00
172_A	205_A	2.181	1.00
168_F	208_Y	2.105	1.00
148_G	206_F	2.097	1.00
292_V	315_G	2.089	1.00
313_R	317_I	2.085	1.00
353_Q	410_K	2.027	1.00
91_S	228_K	2.013	1.00
345_P	349_A	2.001	1.00
192_A	196_Y	1.980	1.00
130_P	134_T	1.966	1.00
334_G	356_K	1.917	1.00
270_G	350_F	1.911	1.00
138_I	195_A	1.910	1.00
346_D	349_A	1.897	1.00
182_L	186_V	1.884	1.00
45_G	48_A	1.879	1.00
36_D	198_T	1.878	1.00
335_K	352_E	1.875	1.00
189_M	196_Y	1.870	1.00
142_G	199_I	1.864	1.00
184_I	194_A	1.847	1.00
100_L	151_F	1.839	1.00
408_G	411_G	1.827	1.00
299_N	307_R	1.825	1.00
40_I	194_A	1.824	1.00
23_M	287_A	1.802	1.00
266_H	346_D	1.798	1.00
80_Q	85_D	1.790	1.00
120_R	129_I	1.788	1.00
39_W	180_A	1.771	1.00
46_A	344_E	1.743	1.00
163_K	167_R	1.738	1.00
80_Q	83_K	1.736	1.00
115_S	133_E	1.697	1.00
20_M	24_L	1.695	1.00
138_I	196_Y	1.693	1.00
141_I	144_L	1.672	1.00
207_L	211_F	1.667	1.00
334_G	352_E	1.663	1.00
295_M	311_I	1.662	1.00
117_L	120_R	1.659	1.00
228_K	231_E	1.659	1.00
300_I	378_A	1.648	1.00
331_W	356_K	1.630	1.00
19_S	291_A	1.621	1.00
310_T	314_L	1.620	1.00
310_T	313_R	1.617	1.00
364_F	421_L	1.611	1.00
168_F	209_G	1.601	1.00
312_A	371_L	1.597	1.00
127_S	265_D	1.579	1.00
76_I	92_Y	1.572	1.00
145_F	206_F	1.571	1.00
319_V	366_G	1.566	1.00
174_V	178_V	1.565	1.00
309_G	313_R	1.544	1.00
181_P	185_S	1.543	1.00
129_I	133_E	1.542	1.00
327_A	331_W	1.531	1.00
35_I	177_T	1.530	1.00
335_K	339_R	1.526	1.00
300_I	308_V	1.518	1.00
181_P	187_F	1.512	1.00
306_K	310_T	1.488	1.00
299_N	304_N	1.483	1.00
138_I	199_I	1.481	1.00
336_Y	339_R	1.475	1.00
180_A	194_A	1.471	1.00
179_L	197_S	1.470	1.00
115_S	137_Q	1.467	1.00
380_A	383_Q	1.452	1.00
407_L	411_G	1.451	1.00
55_S	136_L	1.446	1.00
116_E	130_P	1.444	1.00
12_L	314_L	1.434	1.00
152_I	209_G	1.433	1.00
108_G	144_L	1.433	1.00
80_Q	92_Y	1.426	1.00
339_R	348_V	1.424	1.00
178_V	181_P	1.422	1.00
429_L	432_R	1.420	1.00
183_F	187_F	1.415	1.00
175_L	179_L	1.413	1.00
178_V	182_L	1.411	1.00
425_C	429_L	1.405	1.00
86_I	90_A	1.404	1.00
40_I	52_A	1.402	1.00
211_F	215_K	1.401	1.00
428_F	432_R	1.397	1.00
312_A	374_I	1.395	1.00
11_V	295_M	1.383	1.00
126_E	130_P	1.379	1.00
120_R	126_E	1.378	1.00
127_S	130_P	1.374	1.00
119_L	129_I	1.373	1.00
117_L	121_L	1.349	1.00
167_R	171_F	1.345	1.00
87_K	91_S	1.344	1.00
317_I	321_S	1.338	1.00
352_E	356_K	1.338	1.00
88_G	91_S	1.328	1.00
336_Y	340_L	1.326	1.00
357_W	414_L	1.321	1.00
429_L	433_Y	1.313	1.00
192_A	195_A	1.311	1.00
50_G	269_S	1.303	1.00
48_A	131_L	1.302	1.00
81_K	298_Q	1.301	1.00
116_E	129_I	1.299	1.00
349_A	353_Q	1.297	1.00
183_F	189_M	1.297	1.00
28_L	170_A	1.296	1.00
24_L	166_L	1.292	1.00
331_W	359_A	1.292	1.00
79_Q	83_K	1.290	1.00
12_L	318_A	1.286	1.00
402_L	406_W	1.283	1.00
401_A	405_A	1.280	1.00
36_D	176_N	1.268	1.00
168_F	212_Y	1.267	1.00
305_E	309_G	1.259	1.00
81_K	89_M	1.253	1.00
79_Q	297_G	1.251	1.00
179_L	200_L	1.247	1.00
47_K	265_D	1.246	1.00
319_V	370_V	1.239	1.00
111_G	140_F	1.237	1.00
88_G	231_E	1.231	1.00
44_L	48_A	1.228	1.00
277_L	337_L	1.224	1.00
328_V	332_V	1.223	1.00
82_G	301_G	1.217	1.00
382_L	386_V	1.212	1.00
46_A	266_H	1.211	1.00
383_Q	430_Y	1.208	1.00
338_I	348_V	1.196	1.00
112_F	137_Q	1.188	1.00
230_E	233_A	1.183	1.00
395_L	422_F	1.168	1.00
42_N	343_S	1.164	1.00
37_S	276_R	1.162	1.00
176_N	198_T	1.158	1.00
390_I	394_V	1.153	1.00
411_G	415_G	1.151	1.00
47_K	131_L	1.146	1.00
180_A	197_S	1.145	1.00
183_F	200_L	1.141	1.00
108_G	112_F	1.137	1.00
79_Q	379_G	1.136	1.00
407_L	414_L	1.133	1.00
258_S	262_S	1.133	1.00
37_S	49_L	1.123	1.00
52_A	191_I	1.116	1.00
266_H	350_F	1.109	1.00
51_A	128_M	1.109	1.00
95_A	232_S	1.109	1.00
42_N	185_S	1.108	1.00
171_F	208_Y	1.108	1.00
398_P	402_L	1.099	1.00
350_F	353_Q	1.096	1.00
77_L	158_A	1.095	1.00
99_L	232_S	1.094	1.00
119_L	132_A	1.088	1.00
312_A	431_Y	1.086	1.00
93_I	155_V	1.085	1.00
296_A	308_V	1.083	1.00
181_P	186_V	1.083	1.00
90_A	225_R	1.081	1.00
430_Y	433_Y	1.081	1.00
181_P	184_I	1.080	1.00
289_G	373_G	1.075	1.00
222_S	225_R	1.068	1.00
348_V	351_G	1.067	1.00
240_I	244_L	1.066	1.00
387_L	427_A	1.064	1.00
100_L	147_F	1.054	1.00
113_F	117_L	1.054	1.00
183_F	186_V	1.052	1.00
386_V	390_I	1.047	1.00
186_V	189_M	1.046	1.00
394_V	398_P	1.045	1.00
175_L	201_S	1.036	1.00
15_L	315_G	1.036	1.00
274_V	354_Y	1.033	1.00
321_S	325_V	1.031	1.00
91_S	231_E	1.027	1.00
161_D	165_P	1.024	1.00
368_N	420_F	1.016	1.00
267_V	409_Q	1.016	1.00
137_Q	141_I	1.013	1.00
164_T	212_Y	1.012	1.00
94_N	226_M	1.011	1.00
234_L	237_K	1.010	1.00
371_L	431_Y	1.006	1.00
81_K	159_L	0.995	1.00
36_D	180_A	0.990	1.00
92_Y	231_E	0.986	1.00
96_F	235_I	0.986	1.00
16_V	20_M	0.984	1.00
108_G	141_I	0.982	1.00
196_Y	199_I	0.982	1.00
82_G	302_I	0.981	1.00
101_T	148_G	0.977	1.00
160_G	298_Q	0.976	1.00
314_L	318_A	0.975	1.00
170_A	174_V	0.966	1.00
223_I	226_M	0.961	1.00
299_N	311_I	0.960	1.00
270_G	347_A	0.957	1.00
33_Q	56_S	0.953	1.00
106_G	110_A	0.953	1.00
109_A	113_F	0.949	1.00
400_T	404_S	0.946	1.00
349_A	352_E	0.942	1.00
342_I	347_A	0.936	1.00
264_G	267_V	0.928	1.00
277_L	330_I	0.925	1.00
81_K	86_I	0.924	1.00
259_V	262_S	0.922	1.00
115_S	136_L	0.920	1.00
14_Q	17_L	0.919	1.00
375_V	430_Y	0.919	1.00
219_V	223_I	0.915	1.00
134_T	137_Q	0.914	1.00
325_V	329_M	0.913	1.00
79_Q	300_I	0.913	1.00
354_Y	409_Q	0.910	1.00
287_A	291_A	0.907	1.00
66_I	147_F	0.906	1.00
259_V	263_Y	0.905	1.00
357_W	410_K	0.904	1.00
152_I	206_F	0.904	1.00
22_I	290_T	0.902	1.00
54_V	124_T	0.901	1.00
335_K	349_A	0.896	1.00
131_L	191_I	0.892	1.00
308_V	312_A	0.892	1.00
331_W	335_K	0.890	1.00
346_D	350_F	0.888	1.00
324_L	328_V	0.886	1.00
180_A	198_T	0.886	1.00
273_A	341_F	0.878	1.00
179_L	183_F	0.877	1.00
325_V	328_V	0.874	1.00
38_L	41_G	0.869	1.00
79_Q	234_L	0.868	1.00
409_Q	413_G	0.868	1.00
208_Y	211_F	0.866	1.00
410_K	414_L	0.865	1.00
403_F	407_L	0.864	1.00
199_I	203_G	0.864	1.00
338_I	352_E	0.863	1.00
316_V	367_V	0.861	1.00
59_V	139_Q	0.860	1.00
399_F	418_M	0.857	1.00
113_F	137_Q	0.855	1.00
102_G	106_G	0.850	1.00
332_V	336_Y	0.848	1.00
419_S	423_S	0.846	1.00
203_G	207_L	0.845	1.00
156_L	213_V	0.844	1.00
308_V	378_A	0.842	1.00
149_Y	205_A	0.839	1.00
171_F	175_L	0.839	1.00
35_I	176_N	0.839	1.00
161_D	212_Y	0.838	1.00
271_F	413_G	0.835	1.00
364_F	424_S	0.831	1.00
307_R	310_T	0.831	1.00
18_F	162_S	0.829	1.00
285_A	323_M	0.829	1.00
152_I	213_V	0.828	1.00
39_W	185_S	0.828	1.00
47_K	128_M	0.827	1.00
348_V	352_E	0.826	1.00
244_L	385_L	0.823	1.00
395_L	398_P	0.822	1.00
267_V	350_F	0.821	1.00
391_S	423_S	0.821	1.00
112_F	116_E	0.819	1.00
35_I	173_V	0.819	1.00
141_I	199_I	0.818	1.00
176_N	180_A	0.817	1.00
130_P	133_E	0.815	1.00
299_N	302_I	0.815	1.00
296_A	377_A	0.815	1.00
73_T	77_L	0.813	1.00
167_R	170_A	0.813	1.00
50_G	128_M	0.812	1.00
270_G	351_G	0.812	1.00
296_A	374_I	0.811	1.00
288_A	315_G	0.810	1.00
257_M	261_N	0.809	1.00
248_V	389_L	0.809	1.00
126_E	129_I	0.809	1.00
314_L	317_I	0.805	1.00
196_Y	200_L	0.804	1.00
15_L	314_L	0.804	1.00
96_F	151_F	0.803	1.00
414_L	417_G	0.802	1.00
310_T	317_I	0.801	1.00
115_S	140_F	0.799	1.00
138_I	141_I	0.797	1.00
161_D	216_H	0.793	1.00
166_L	170_A	0.792	1.00
109_A	112_F	0.791	1.00
28_L	173_V	0.791	1.00
231_E	234_L	0.790	1.00
204_I	208_Y	0.788	1.00
40_I	184_I	0.782	1.00
399_F	403_F	0.778	1.00
87_K	225_R	0.778	1.00
110_A	114_L	0.776	1.00
276_R	341_F	0.773	1.00
90_A	222_S	0.773	1.00
98_V	102_G	0.771	1.00
321_S	324_L	0.769	1.00
211_F	214_I	0.769	1.00
237_K	382_L	0.769	1.00
156_L	209_G	0.766	1.00
46_A	347_A	0.765	1.00
32_F	198_T	0.764	1.00
14_Q	298_Q	0.762	1.00
221_F	224_P	0.762	1.00
14_Q	295_M	0.761	1.00
345_P	348_V	0.760	1.00
261_N	268_V	0.758	1.00
12_L	16_V	0.755	1.00
180_A	184_I	0.754	1.00
188_R	192_A	0.754	1.00
76_I	238_L	0.750	1.00
157_R	165_P	0.750	1.00
263_Y	404_S	0.749	1.00
306_K	313_R	0.748	1.00
75_T	79_Q	0.748	1.00
41_G	49_L	0.748	1.00
273_A	351_G	0.745	1.00
320_I	324_L	0.744	1.00
260_V	409_Q	0.743	1.00
128_M	268_V	0.743	1.00
12_L	317_I	0.743	1.00
134_T	191_I	0.743	1.00
415_G	419_S	0.739	1.00
176_N	201_S	0.737	1.00
78_S	158_A	0.736	1.00
65_F	243_G	0.733	1.00
324_L	363_P	0.731	1.00
234_L	379_G	0.731	1.00
51_A	191_I	0.730	1.00
76_I	80_Q	0.728	1.00
44_L	188_R	0.727	1.00
210_L	214_I	0.727	1.00
259_V	401_A	0.726	1.00
367_V	424_S	0.725	1.00
357_W	417_G	0.724	1.00
421_L	425_C	0.724	1.00
31_S	35_I	0.722	1.00
94_N	225_R	0.721	1.00
83_K	301_G	0.720	1.00
299_N	308_V	0.719	1.00
404_S	411_G	0.719	1.00
315_G	370_V	0.717	1.00
136_L	140_F	0.717	1.00
360_F	363_P	0.716	1.00
333_F	337_L	0.715	1.00
123_K	126_E	0.715	1.00
19_S	287_A	0.715	1.00
77_L	155_V	0.714	1.00
317_I	320_I	0.714	1.00
334_G	355_L	0.708	1.00
34_F	280_I	0.708	1.00
25_G	169_I	0.707	1.00
28_L	31_S	0.700	1.00
135_Y	180_A	0.699	1.00
236_L	240_I	0.699	1.00
98_V	226_M	0.698	1.00
356_K	360_F	0.698	1.00
262_S	405_A	0.696	1.00
306_K	309_G	0.696	1.00
104_S	144_L	0.696	1.00
260_V	412_I	0.694	1.00
288_A	319_V	0.691	1.00
38_L	340_L	0.689	1.00
247_M	251_G	0.689	1.00
288_A	322_C	0.688	1.00
119_L	136_L	0.687	1.00
260_V	271_F	0.687	1.00
189_M	192_A	0.686	1.00
140_F	143_I	0.685	1.00
156_L	164_T	0.685	1.00
141_I	145_F	0.685	1.00
224_P	227_P	0.684	1.00
296_A	312_A	0.681	1.00
320_I	366_G	0.680	1.00
15_L	291_A	0.678	1.00
383_Q	387_L	0.676	1.00
403_F	411_G	0.674	1.00
239_G	243_G	0.672	1.00
334_G	338_I	0.671	1.00
171_F	204_I	0.669	1.00
51_A	132_A	0.669	1.00
77_L	89_M	0.668	1.00
38_L	42_N	0.668	1.00
331_W	334_G	0.667	1.00
347_A	351_G	0.667	1.00
164_T	208_Y	0.667	1.00
114_L	118_L	0.665	1.00
88_G	92_Y	0.664	1.00
259_V	400_T	0.664	1.00
411_G	414_L	0.664	1.00
323_M	366_G	0.661	1.00
270_G	354_Y	0.660	1.00
40_I	44_L	0.656	1.00
142_G	145_F	0.653	1.00
27_A	31_S	0.650	1.00
329_M	333_F	0.650	1.00
373_G	377_A	0.649	1.00
195_A	199_I	0.648	1.00
137_Q	192_A	0.645	1.00
140_F	144_L	0.645	1.00
35_I	39_W	0.644	1.00
218_L	222_S	0.642	1.00
40_I	191_I	0.642	1.00
240_I	243_G	0.640	1.00
142_G	202_Q	0.640	1.00
238_L	381_M	0.639	1.00
305_E	308_V	0.639	1.00
91_S	94_N	0.639	1.00
193_G	197_S	0.639	1.00
292_V	296_A	0.637	1.00
335_K	348_V	0.636	1.00
128_M	131_L	0.635	1.00
127_S	131_L	0.633	1.00
263_Y	267_V	0.633	1.00
322_C	326_I	0.632	1.00
40_I	48_A	0.632	1.00
112_F	141_I	0.632	1.00
395_L	399_F	0.630	1.00
300_I	305_E	0.630	1.00
47_K	50_G	0.630	1.00
344_E	348_V	0.630	1.00
91_S	95_A	0.630	1.00
68_G	243_G	0.630	1.00
426_A	429_L	0.628	1.00
48_A	51_A	0.627	1.00
101_T	105_I	0.627	1.00
83_K	303_G	0.626	1.00
170_A	173_V	0.621	1.00
284_P	322_C	0.620	1.00
152_I	210_L	0.619	1.00
62_V	143_I	0.619	1.00
87_K	90_A	0.619	1.00
371_L	427_A	0.619	1.00
332_V	335_K	0.619	1.00
183_F	194_A	0.617	1.00
200_L	203_G	0.617	1.00
278_D	362_Y	0.613	1.00
396_R	419_S	0.613	1.00
201_S	204_I	0.613	1.00
75_T	238_L	0.610	1.00
255_A	397_Y	0.610	1.00
14_Q	307_R	0.609	1.00
298_Q	302_I	0.608	1.00
266_H	269_S	0.607	1.00
32_F	172_A	0.606	1.00
129_I	132_A	0.606	1.00
281_I	326_I	0.606	1.00
112_F	115_S	0.606	1.00
259_V	404_S	0.606	1.00
31_S	173_V	0.605	1.00
397_Y	401_A	0.602	1.00
293_N	376_R	0.601	1.00
175_L	200_L	0.600	1.00
403_F	406_W	0.599	1.00
45_G	131_L	0.598	1.00
77_L	92_Y	0.597	1.00
48_A	190_G	0.595	1.00
241_P	385_L	0.592	1.00
256_I	412_I	0.591	1.00
342_I	345_P	0.590	1.00
11_V	314_L	0.590	1.00
282_T	365_I	0.590	1.00
318_A	321_S	0.589	1.00
208_Y	212_Y	0.588	1.00
219_V	224_P	0.587	1.00
94_N	98_V	0.586	1.00
32_F	202_Q	0.586	1.00
230_E	234_L	0.585	1.00
116_E	137_Q	0.584	1.00
267_V	270_G	0.581	1.00
74_L	154_T	0.581	1.00
110_A	113_F	0.581	1.00
69_L	243_G	0.581	1.00
153_S	157_R	0.580	1.00
85_D	91_S	0.580	1.00
145_F	199_I	0.579	1.00
104_S	140_F	0.577	1.00
185_S	189_M	0.577	1.00
374_I	378_A	0.577	1.00
371_L	428_F	0.576	1.00
171_F	174_V	0.576	1.00
134_T	138_I	0.576	1.00
49_L	342_I	0.575	1.00
119_L	124_T	0.573	1.00
316_V	320_I	0.573	1.00
175_L	178_V	0.573	1.00
49_L	273_A	0.571	1.00
219_V	222_S	0.570	1.00
223_I	227_P	0.568	1.00
320_I	367_V	0.568	1.00
197_S	201_S	0.567	1.00
398_P	401_A	0.567	1.00
399_F	402_L	0.566	1.00
119_L	133_E	0.565	1.00
124_T	261_N	0.565	1.00
135_Y	194_A	0.565	1.00
176_N	197_S	0.563	1.00
387_L	426_A	0.562	1.00
220_P	223_I	0.558	1.00
270_G	413_G	0.557	1.00
84_D	302_I	0.556	1.00
232_S	236_L	0.556	1.00
183_F	196_Y	0.556	1.00
144_L	203_G	0.556	1.00
71_N	290_T	0.555	1.00
128_M	265_D	0.555	1.00
69_L	103_L	0.554	1.00
266_H	347_A	0.554	1.00
50_G	53_A	0.553	1.00
344_E	347_A	0.553	1.00
44_L	191_I	0.553	1.00
402_L	405_A	0.552	1.00
128_M	132_A	0.551	1.00
212_Y	216_H	0.551	1.00
375_V	380_A	0.551	1.00
401_A	404_S	0.551	1.00
266_H	344_E	0.550	1.00
388_N	391_S	0.548	1.00
259_V	405_A	0.547	1.00
214_I	217_K	0.547	1.00
285_A	366_G	0.547	1.00
381_M	385_L	0.545	1.00
177_T	181_P	0.544	1.00
221_F	226_M	0.544	1.00
75_T	297_G	0.544	1.00
367_V	428_F	0.544	1.00
371_L	424_S	0.543	1.00
279_S	282_T	0.541	1.00
33_Q	139_Q	0.541	1.00
22_I	287_A	0.539	1.00
101_T	104_S	0.539	1.00
157_R	162_S	0.539	1.00
353_Q	356_K	0.539	1.00
149_Y	153_S	0.539	1.00
86_I	218_L	0.538	1.00
54_V	132_A	0.538	1.00
359_A	363_P	0.537	1.00
189_M	193_G	0.537	1.00
44_L	184_I	0.536	1.00
400_T	412_I	0.536	1.00
424_S	428_F	0.535	1.00
149_Y	206_F	0.533	1.00
87_K	224_P	0.533	1.00
56_S	60_L	0.533	1.00
89_M	93_I	0.530	1.00
168_F	205_A	0.530	1.00
11_V	310_T	0.529	1.00
16_V	318_A	0.526	0.99
391_S	426_A	0.526	0.99
368_N	423_S	0.525	0.99
320_I	363_P	0.525	0.99
190_G	193_G	0.524	0.99
396_R	400_T	0.521	0.99
401_A	406_W	0.520	0.99
256_I	400_T	0.518	0.99
252_G	392_F	0.518	0.99
35_I	38_L	0.517	0.99
313_R	316_V	0.516	0.99
95_A	231_E	0.516	0.99
273_A	347_A	0.516	0.99
425_C	428_F	0.516	0.99
292_V	370_V	0.515	0.99
414_L	418_M	0.515	0.99
400_T	403_F	0.514	0.99
54_V	268_V	0.514	0.99
248_V	385_L	0.513	0.99
105_I	108_G	0.511	0.99
80_Q	231_E	0.511	0.99
312_A	316_V	0.510	0.99
15_L	318_A	0.510	0.99
274_V	355_L	0.508	0.99
339_R	343_S	0.507	0.99
293_N	373_G	0.507	0.99
316_V	371_L	0.507	0.99
112_F	140_F	0.507	0.99
124_T	129_I	0.506	0.99
19_S	23_M	0.506	0.99
422_F	426_A	0.505	0.99
342_I	348_V	0.503	0.99
390_I	426_A	0.502	0.99
154_T	157_R	0.502	0.99
313_R	431_Y	0.501	0.99
395_L	419_S	0.501	0.99
327_A	363_P	0.500	0.99
408_G	415_G	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3mktA	1	0.9933	100	0.285	Contact Map
4humA	1	0.9978	100	0.294	Contact Map
4lz6A	1	0.991	100	0.3	Contact Map
3w4tA	1	0.9798	100	0.365	Contact Map
4xnjA	1	0.8787	78.7	0.941	Contact Map
3wdoA	1	0.8674	76.1	0.942	Contact Map
2cfqA	1	0.8742	55.4	0.95	Contact Map
1pw4A	1	0.8809	54.1	0.95	Contact Map
3o7qA	1	0.8404	43.1	0.953	Contact Map
4tphA	2	0.8292	33.7	0.956	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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