GREMLIN Database
YPJQ - Uncharacterized protein YpjQ
UniProt: P54173 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 177 (156)
Sequences: 452 (262)
Seq/√Len: 20.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
81_E85_H6.6911.00
69_A80_P4.6571.00
24_I48_M4.3071.00
77_K88_E3.7701.00
84_Q88_E3.6841.00
25_E48_M3.6021.00
19_K72_Q3.3341.00
10_V14_K2.8820.99
66_T94_Y2.6700.99
119_L146_A2.6450.98
27_I149_A2.2450.96
74_A79_L2.2410.96
130_L145_V2.0890.93
70_L79_L2.0500.93
11_D15_D2.0060.92
38_Y121_K1.9810.91
119_L127_I1.9640.91
87_V139_T1.9390.91
50_N155_R1.8980.90
14_K52_E1.8780.89
49_E53_K1.8210.87
30_I124_I1.7860.86
115_N147_A1.7750.86
99_I103_S1.6740.83
33_K122_E1.5610.78
9_M96_I1.5490.77
33_K127_I1.5320.76
26_D126_I1.5210.76
126_I129_E1.4810.74
10_V56_N1.4710.73
29_R44_L1.4690.73
138_H141_L1.4320.71
13_T144_I1.4260.71
22_V141_L1.4010.70
145_V149_A1.3630.67
116_F119_L1.3180.65
99_I106_N1.3130.64
33_K116_F1.3070.64
68_L141_L1.3060.64
131_D138_H1.2850.63
144_I154_S1.2810.62
7_N11_D1.2640.61
77_K84_Q1.2280.59
106_N112_G1.2210.59
144_I148_L1.2090.58
73_L79_L1.2000.57
127_I131_D1.1980.57
87_V137_I1.1940.57
16_M19_K1.1840.56
69_A146_A1.1830.56
84_Q138_H1.1720.55
29_R129_E1.1670.55
24_I52_E1.1420.53
103_S126_I1.1390.53
27_I145_V1.1350.53
30_I94_Y1.1320.53
32_Q36_E1.1140.52
9_M12_I1.1100.51
8_E156_I1.1060.51
51_V152_A1.0990.51
27_I51_V1.0830.50
133_S138_H1.0790.49
100_I161_Q1.0710.49
16_M65_L1.0520.48
128_K131_D1.0490.47
15_D19_K1.0480.47
31_V91_E1.0190.45
118_Y122_E1.0140.45
70_L83_L1.0120.45
85_H88_E1.0080.45
69_A72_Q0.9990.44
11_D52_E0.9980.44
25_E44_L0.9920.44
92_P139_T0.9880.43
28_A48_M0.9870.43
39_N50_N0.9680.42
79_L84_Q0.9670.42
67_G121_K0.9520.41
16_M69_A0.9410.40
89_T134_P0.9290.40
104_I107_V0.9290.40
96_I100_I0.9260.39
62_H115_N0.9170.39
33_K119_L0.9110.38
107_V112_G0.9070.38
10_V13_T0.9060.38
41_N72_Q0.8960.37
61_I101_P0.8910.37
80_P84_Q0.8830.37
124_I128_K0.8820.37
36_E40_P0.8810.37
12_I156_I0.8770.36
99_I113_L0.8550.35
137_I161_Q0.8490.35
132_E135_D0.8420.34
89_T161_Q0.8380.34
121_K158_H0.8380.34
64_V68_L0.8350.34
11_D81_E0.8340.34
50_N144_I0.8290.33
116_F146_A0.8210.33
10_V52_E0.8200.33
20_R75_E0.8110.32
85_H89_T0.8110.32
27_I77_K0.8040.32
18_N23_M0.8030.32
30_I119_L0.7860.31
144_I147_A0.7800.31
63_A110_S0.7620.30
64_V103_S0.7580.29
44_L52_E0.7570.29
80_P119_L0.7560.29
110_S115_N0.7490.29
30_I62_H0.7470.29
11_D129_E0.7460.29
28_A51_V0.7450.29
104_I112_G0.7400.28
92_P144_I0.7400.28
104_I115_N0.7290.28
81_E162_D0.7260.28
16_M131_D0.7230.27
66_T99_I0.7170.27
24_I51_V0.7150.27
92_P105_V0.7050.27
107_V116_F0.7040.26
27_I153_A0.7000.26
64_V153_A0.6950.26
60_I104_I0.6930.26
112_G151_A0.6920.26
69_A119_L0.6900.26
91_E130_L0.6890.26
103_S112_G0.6830.25
25_E29_R0.6830.25
63_A93_L0.6800.25
112_G115_N0.6800.25
10_V96_I0.6760.25
99_I115_N0.6760.25
29_R33_K0.6760.25
149_A153_A0.6760.25
106_N118_Y0.6750.25
61_I70_L0.6740.25
39_N115_N0.6730.25
17_L64_V0.6690.25
113_L116_F0.6690.25
133_S136_G0.6680.25
45_S48_M0.6670.25
24_I87_V0.6660.25
86_L92_P0.6640.24
83_L87_V0.6580.24
52_E148_L0.6570.24
124_I147_A0.6510.24
16_M86_L0.6500.24
104_I151_A0.6470.24
9_M155_R0.6440.23
66_T106_N0.6420.23
124_I137_I0.6400.23
69_A116_F0.6370.23
9_M56_N0.6350.23
51_V149_A0.6350.23
66_T131_D0.6340.23
66_T104_I0.6330.23
102_L116_F0.6300.23
60_I64_V0.6300.23
107_V115_N0.6280.23
72_Q76_Q0.6260.23
66_T107_V0.6240.23
92_P132_E0.6240.23
16_M72_Q0.6220.22
69_A73_L0.6200.22
39_N43_P0.6180.22
103_S106_N0.6170.22
10_V65_L0.6150.22
19_K41_N0.6140.22
102_L154_S0.6140.22
16_M122_E0.6090.22
9_M153_A0.6090.22
57_K158_H0.6070.22
35_Q109_G0.6060.22
23_M45_S0.6060.22
122_E146_A0.6040.22
29_R149_A0.6020.22
70_L101_P0.6020.22
9_M159_T0.5990.21
61_I131_D0.5960.21
130_L149_A0.5960.21
33_K124_I0.5940.21
94_Y99_I0.5930.21
125_G137_I0.5920.21
12_I65_L0.5910.21
60_I154_S0.5900.21
61_I75_E0.5890.21
26_D44_L0.5880.21
72_Q80_P0.5860.21
86_L128_K0.5840.21
47_C153_A0.5820.21
116_F127_I0.5790.21
8_E45_S0.5780.20
84_Q87_V0.5750.20
41_N44_L0.5720.20
122_E128_K0.5710.20
24_I40_P0.5660.20
147_A151_A0.5640.20
48_M122_E0.5600.20
68_L138_H0.5600.20
87_V131_D0.5600.20
19_K23_M0.5580.20
92_P156_I0.5530.19
65_L161_Q0.5490.19
63_A139_T0.5470.19
15_D46_V0.5420.19
88_E137_I0.5400.19
11_D32_Q0.5380.19
137_I144_I0.5380.19
70_L159_T0.5380.19
34_L94_Y0.5380.19
28_A44_L0.5380.19
132_E136_G0.5370.19
73_L76_Q0.5340.19
13_T148_L0.5320.19
20_R141_L0.5270.18
22_V136_G0.5240.18
65_L87_V0.5230.18
96_I104_I0.5210.18
62_H68_L0.5180.18
110_S139_T0.5170.18
11_D18_N0.5160.18
14_K96_I0.5160.18
30_I64_V0.5150.18
147_A154_S0.5120.18
18_N46_V0.5090.18
106_N115_N0.5070.18
80_P146_A0.5060.18
73_L153_A0.5040.17
127_I134_P0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1tlqA 4 0.9096 100 0.33 Contact Map
1rfzA 4 0.9096 100 0.379 Contact Map
1y9iA 4 0.8927 100 0.398 Contact Map
2vwaA 1 0.2599 37 0.957 Contact Map
1p3y1 6 0.2542 23.5 0.961 Contact Map
2rreA 1 0.3503 19.1 0.963 Contact Map
3hsqA 3 0.4407 14.5 0.965 Contact Map
4r4eB 2 0.2147 12.9 0.966 Contact Map
3oqpA 2 0.3277 12 0.966 Contact Map
3m6zA 1 0.4294 11 0.967 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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