GREMLIN Database
YPJP - Uncharacterized protein YpjP
UniProt: P54172 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 203 (200)
Sequences: 124 (104)
Seq/√Len: 7.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
140_K155_R3.8660.96
106_K109_N3.7670.95
94_V107_I3.4910.92
24_P27_L3.4860.92
97_D102_E3.2600.89
136_G160_R2.6620.77
99_Y190_I2.4810.71
152_D155_R2.4740.71
163_P189_S2.4080.69
108_E142_F2.3710.68
75_L201_M2.2330.63
137_K199_N2.1720.61
106_K150_G2.1610.60
87_F187_L2.1450.60
83_S99_Y2.1450.60
126_D147_R2.1160.58
39_L185_H2.0790.57
146_N149_T2.0020.54
16_V194_R1.9200.51
136_G170_F1.8370.48
130_S143_N1.8090.46
17_T23_P1.7600.45
14_T27_L1.7590.45
18_F83_S1.6950.42
71_Y75_L1.6320.40
95_I140_K1.6260.39
95_I154_L1.6190.39
19_G200_W1.6130.39
22_S187_L1.5790.38
6_R169_W1.5760.38
156_F188_G1.5660.37
130_S140_K1.5490.37
134_S138_T1.5440.36
135_A201_M1.5340.36
49_D149_T1.5290.36
80_E163_P1.5260.36
29_A110_V1.5170.35
87_F99_Y1.5120.35
8_T154_L1.5120.35
7_K10_V1.5020.35
143_N163_P1.4970.35
24_P110_V1.4840.34
60_D180_G1.4810.34
4_W7_K1.4590.33
21_V187_L1.4410.33
13_F76_L1.4410.33
94_V182_Q1.4390.33
68_F153_L1.4320.32
80_E100_R1.4320.32
83_S87_F1.4290.32
161_D171_N1.4280.32
89_S169_W1.4200.32
6_R193_D1.4190.32
22_S138_T1.3980.31
7_K110_V1.3950.31
13_F24_P1.3950.31
14_T69_Q1.3920.31
143_N152_D1.3890.31
21_V87_F1.3880.31
12_L15_I1.3620.30
36_P67_L1.3370.29
32_P135_A1.3360.29
21_V163_P1.3170.29
160_R170_F1.2870.28
193_D196_T1.2850.28
140_K171_N1.2730.27
93_P138_T1.2640.27
91_I170_F1.2570.27
89_S130_S1.2460.26
6_R160_R1.2410.26
143_N155_R1.2310.26
42_N101_K1.2110.25
76_L114_Y1.2100.25
22_S87_F1.2070.25
32_P169_W1.1890.25
18_F68_F1.1790.24
121_D153_L1.1730.24
7_K190_I1.1730.24
74_Q162_H1.1670.24
11_V180_G1.1620.24
155_R188_G1.1540.24
78_S110_V1.1510.24
87_F143_N1.1340.23
137_K163_P1.1230.23
107_I142_F1.1190.23
90_R108_E1.1110.22
13_F25_A1.1050.22
110_V190_I1.0950.22
161_D170_F1.0780.22
178_E182_Q1.0620.21
100_R182_Q1.0590.21
108_E196_T1.0560.21
50_E144_V1.0530.21
83_S142_F1.0440.21
166_D169_W1.0410.21
15_I189_S1.0370.21
83_S161_D1.0280.20
130_S155_R1.0260.20
19_G23_P1.0140.20
5_M34_G1.0130.20
20_L113_D1.0120.20
79_A105_P1.0020.20
9_L125_Q1.0020.20
96_E187_L0.9890.19
81_D101_K0.9850.19
98_D102_E0.9710.19
130_S190_I0.9700.19
6_R107_I0.9580.19
30_D112_S0.9570.19
3_L155_R0.9490.18
104_L163_P0.9440.18
91_I165_H0.9390.18
64_P69_Q0.9320.18
23_P200_W0.9240.18
62_R65_E0.9190.18
101_K147_R0.9120.18
87_F154_L0.9090.17
94_V181_F0.9080.17
115_L119_Q0.9050.17
136_G169_W0.9030.17
98_D142_F0.9030.17
146_N189_S0.9020.17
131_S142_F0.8980.17
13_F27_L0.8870.17
65_E82_Q0.8840.17
188_G195_N0.8840.17
3_L165_H0.8830.17
14_T92_A0.8820.17
121_D177_A0.8760.17
7_K12_L0.8760.17
130_S150_G0.8730.17
99_Y142_F0.8720.17
96_E154_L0.8690.17
6_R136_G0.8640.16
8_T95_I0.8600.16
57_E90_R0.8560.16
171_N189_S0.8530.16
15_I128_V0.8530.16
8_T16_V0.8510.16
113_D153_L0.8510.16
7_K13_F0.8500.16
2_K13_F0.8480.16
10_V23_P0.8470.16
2_K28_M0.8460.16
87_F127_V0.8440.16
8_T138_T0.8400.16
89_S143_N0.8370.16
111_I125_Q0.8300.16
107_I133_P0.8300.16
135_A165_H0.8280.16
13_F28_M0.8270.16
87_F95_I0.8210.16
100_R130_S0.8170.15
66_L153_L0.8110.15
24_P111_I0.8090.15
130_S134_S0.8040.15
114_Y140_K0.7980.15
114_Y176_T0.7950.15
124_Y155_R0.7950.15
10_V80_E0.7900.15
93_P190_I0.7880.15
144_V195_N0.7870.15
143_N162_H0.7860.15
14_T103_I0.7820.15
96_E134_S0.7820.15
142_F156_F0.7800.15
52_D116_A0.7770.15
1_M201_M0.7750.15
131_S144_V0.7740.15
166_D187_L0.7710.15
43_D106_K0.7690.14
103_I188_G0.7680.14
80_E84_F0.7670.14
154_L187_L0.7670.14
152_D188_G0.7640.14
137_K151_E0.7630.14
126_D148_T0.7630.14
46_A85_L0.7590.14
163_P170_F0.7570.14
22_S183_S0.7560.14
170_F201_M0.7550.14
1_M18_F0.7530.14
89_S199_N0.7500.14
20_L155_R0.7460.14
138_T193_D0.7420.14
7_K23_P0.7380.14
25_A28_M0.7310.14
2_K162_H0.7280.14
110_V116_A0.7180.14
134_S161_D0.7150.13
193_D202_S0.7150.13
38_S97_D0.7140.13
22_S93_P0.7140.13
54_Y72_K0.7130.13
91_I117_T0.7110.13
24_P29_A0.7100.13
7_K166_D0.7100.13
30_D40_E0.7100.13
37_S73_E0.7100.13
138_T202_S0.7090.13
80_E182_Q0.7080.13
13_F77_D0.7070.13
160_R169_W0.7040.13
104_L170_F0.7030.13
9_L92_A0.6980.13
26_A38_S0.6960.13
160_R201_M0.6920.13
127_V157_H0.6910.13
15_I161_D0.6880.13
18_F87_F0.6850.13
2_K21_V0.6810.13
20_L191_Y0.6800.13
114_Y149_T0.6760.13
67_L186_E0.6740.13
4_W19_G0.6740.13
30_D94_V0.6730.13
27_L78_S0.6680.13
180_G185_H0.6670.13
28_M161_D0.6640.13
87_F163_P0.6640.13
93_P135_A0.6610.13
150_G163_P0.6570.12
13_F110_V0.6550.12
110_V176_T0.6530.12
138_T160_R0.6520.12
11_V124_Y0.6500.12
107_I156_F0.6500.12
146_N151_E0.6420.12
109_N134_S0.6400.12
21_V80_E0.6390.12
104_L160_R0.6380.12
111_I154_L0.6340.12
110_V138_T0.6330.12
62_R149_T0.6290.12
54_Y62_R0.6260.12
96_E104_L0.6250.12
101_K120_D0.6200.12
143_N154_L0.6190.12
103_I117_T0.6180.12
71_Y119_Q0.6180.12
84_F114_Y0.6060.12
160_R193_D0.6010.12
65_E69_Q0.6000.12
130_S146_N0.5960.11
21_V95_I0.5950.11
83_S108_E0.5950.11
110_V124_Y0.5910.11
129_I140_K0.5910.11
9_L34_G0.5890.11
87_F190_I0.5880.11
74_Q84_F0.5850.11
142_F171_N0.5830.11
27_L31_K0.5810.11
95_I157_H0.5780.11
89_S126_D0.5780.11
87_F130_S0.5770.11
144_V194_R0.5720.11
103_I131_S0.5660.11
112_S148_T0.5660.11
2_K163_P0.5650.11
115_L124_Y0.5640.11
130_S189_S0.5630.11
98_D108_E0.5620.11
46_A92_A0.5610.11
57_E67_L0.5590.11
68_F151_E0.5580.11
93_P154_L0.5560.11
113_D163_P0.5550.11
39_L146_N0.5540.11
98_D131_S0.5540.11
33_S177_A0.5500.11
21_V154_L0.5470.11
71_Y124_Y0.5450.11
111_I143_N0.5420.11
153_L183_S0.5400.11
83_S98_D0.5360.11
31_K160_R0.5330.10
100_R160_R0.5310.10
19_G160_R0.5290.10
105_P191_Y0.5280.10
161_D193_D0.5270.10
89_S202_S0.5240.10
43_D63_D0.5200.10
7_K19_G0.5200.10
113_D146_N0.5190.10
1_M58_S0.5190.10
12_L40_E0.5190.10
102_E117_T0.5150.10
111_I152_D0.5140.10
106_K186_E0.5080.10
66_L118_L0.5060.10
87_F150_G0.5040.10
96_E193_D0.5040.10
17_T200_W0.5030.10
82_Q141_I0.5020.10
169_W199_N0.5020.10
2_K166_D0.5020.10
4_W200_W0.5010.10
95_I163_P0.5000.10
95_I114_Y0.5000.10
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2wgoA 1 0.3744 9.3 0.972 Contact Map
1jqkA 3 0.3498 6.8 0.974 Contact Map
4pj0U 1 0.4138 6.5 0.974 Contact Map
1gnlA 1 0.3005 5.7 0.975 Contact Map
1m55A 1 0.532 5.1 0.975 Contact Map
1gntA 1 0.2956 4.4 0.976 Contact Map
3rvyA 3 0.1576 4.3 0.976 Contact Map
3layA 5 0.335 3.8 0.977 Contact Map
4udxX 2 0.3695 3.5 0.977 Contact Map
2lk9A 1 0.1182 3 0.978 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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