GREMLIN Database
YPGQ - Uncharacterized protein YpgQ
UniProt: P54168 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 205 (189)
Sequences: 1524 (1149)
Seq/√Len: 83.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
141_A155_A4.0891.00
164_L190_V3.2331.00
44_E174_T2.7031.00
40_I174_T2.6411.00
121_Q171_N2.5931.00
41_G46_A2.5701.00
10_I53_T2.5351.00
11_R34_A2.3861.00
9_Q83_F2.3781.00
174_T177_E2.3131.00
34_A52_E2.2861.00
86_G89_N2.2731.00
47_D89_N2.2201.00
185_F192_Q2.1811.00
37_A51_V2.1631.00
135_A138_F2.1541.00
170_M179_A2.1401.00
147_G150_G2.1291.00
156_Y190_V2.0581.00
38_A52_E2.0171.00
170_M175_A1.9731.00
51_V120_V1.9711.00
167_K183_H1.9581.00
184_N188_Q1.9421.00
171_N175_A1.9361.00
53_T93_V1.9311.00
146_H155_A1.9161.00
13_W79_Q1.8641.00
17_I75_E1.8381.00
34_A38_A1.8071.00
41_G48_L1.8021.00
193_L197_I1.7951.00
163_L186_M1.7781.00
167_K180_E1.7761.00
121_Q125_R1.7601.00
181_E192_Q1.7211.00
115_I118_K1.7181.00
43_K177_E1.6961.00
183_H187_L1.6391.00
112_P117_G1.6361.00
99_R117_G1.6191.00
157_A161_H1.6001.00
68_T71_L1.5651.00
185_F188_Q1.5581.00
180_E184_N1.5561.00
46_A51_V1.5200.99
154_S157_A1.5040.99
34_A56_L1.4950.99
184_N187_L1.4860.99
166_L170_M1.4820.99
24_G65_L1.4790.99
100_M117_G1.4260.99
49_F89_N1.4210.99
46_A119_A1.4090.99
185_F189_F1.4090.99
178_L181_E1.3910.99
165_R169_M1.3520.99
77_Y94_I1.3230.99
188_Q192_Q1.3200.99
141_A146_H1.3100.98
10_I79_Q1.3100.98
138_F142_G1.3070.98
43_K174_T1.3050.98
95_H99_R1.2780.98
137_A155_A1.2750.98
156_Y193_L1.2620.98
61_I72_S1.2580.98
11_R15_Q1.2450.98
36_L178_L1.2300.98
81_V87_K1.2240.98
53_T85_V1.2160.98
187_L191_R1.1930.97
61_I76_V1.1880.97
181_E195_K1.1680.97
87_K91_D1.1680.97
186_M190_V1.1600.97
36_L39_Y1.1420.96
129_I183_H1.1210.96
158_H162_K1.1150.96
42_E48_L1.1120.96
173_D176_R1.1100.96
85_V89_N1.1090.96
41_G51_V1.1040.96
23_S139_M1.0910.95
46_A115_I1.0900.95
22_S65_L1.0880.95
172_T175_A1.0860.95
54_A96_I1.0830.95
77_Y81_V1.0590.94
39_Y43_K1.0550.94
190_V194_E1.0330.94
15_Q27_W1.0300.94
77_Y90_A1.0250.93
118_K171_N1.0220.93
99_R110_K1.0200.93
92_R116_E1.0120.93
78_D82_F1.0040.93
21_E24_G0.9880.92
164_L183_H0.9830.92
14_V18_L0.9790.92
79_Q83_F0.9670.91
139_M155_A0.9600.91
76_V80_L0.9530.91
73_V98_T0.9520.91
160_F190_V0.9410.90
30_V34_A0.9400.90
99_R113_L0.9350.90
135_A148_L0.9220.89
128_A158_H0.9170.89
49_F85_V0.9130.89
140_F144_K0.8990.88
77_Y91_D0.8850.87
76_V97_I0.8830.87
134_I189_F0.8760.87
40_I178_L0.8740.87
30_V127_D0.8730.86
28_H31_S0.8700.86
126_L175_A0.8650.86
31_S35_D0.8580.86
129_I137_A0.8570.85
164_L187_L0.8550.85
69_V72_S0.8510.85
160_F194_E0.8400.84
156_Y160_F0.8330.84
10_I57_V0.8290.84
131_A196_D0.8210.83
25_H136_R0.8210.83
75_E78_D0.8190.83
138_F178_L0.8180.83
39_Y174_T0.8100.82
49_F53_T0.8060.82
47_D92_R0.8010.81
54_A100_M0.7960.81
73_V76_V0.7960.81
113_L118_K0.7930.81
105_R109_A0.7930.81
14_V27_W0.7930.81
39_Y178_L0.7900.80
37_A120_V0.7880.80
150_G157_A0.7830.80
10_I13_W0.7810.80
175_A178_L0.7800.80
165_R168_D0.7780.79
128_A162_K0.7690.79
36_L40_I0.7630.78
187_L194_E0.7620.78
40_I175_A0.7560.77
103_R158_H0.7520.77
61_I73_V0.7520.77
95_H114_S0.7510.77
164_L186_M0.7470.77
151_D197_I0.7440.76
65_L101_S0.7400.76
153_Q157_A0.7370.76
101_S125_R0.7350.75
176_R180_E0.7310.75
158_H166_L0.7290.75
188_Q191_R0.7280.75
18_L100_M0.7270.75
182_R192_Q0.7240.74
45_K115_I0.7230.74
57_V76_V0.7230.74
94_I98_T0.7220.74
121_Q158_H0.7150.73
24_G171_N0.7130.73
50_I92_R0.7100.73
90_A94_I0.7090.73
96_I100_M0.7080.73
164_L179_A0.7070.73
103_R121_Q0.7070.73
62_D65_L0.7070.73
25_H162_K0.7060.73
89_N93_V0.7040.72
11_R31_S0.7020.72
61_I66_P0.6980.72
127_D133_G0.6970.72
41_G55_A0.6950.71
57_V60_L0.6940.71
133_G170_M0.6940.71
159_F164_L0.6920.71
41_G45_K0.6900.71
61_I75_E0.6840.70
102_F165_R0.6830.70
162_K166_L0.6820.70
131_A185_F0.6750.69
97_I100_M0.6750.69
18_L30_V0.6750.69
101_S158_H0.6740.69
21_E65_L0.6690.68
66_P72_S0.6690.68
36_L192_Q0.6600.67
66_P75_E0.6570.67
31_S34_A0.6540.67
195_K198_P0.6530.67
62_D161_H0.6470.66
77_Y88_E0.6460.66
102_F166_L0.6440.66
80_L90_A0.6410.65
74_S98_T0.6340.64
146_H154_S0.6310.64
60_L72_S0.6300.64
135_A178_L0.6270.63
74_S77_Y0.6260.63
127_D149_Y0.6240.63
23_S143_A0.6220.63
10_I83_F0.6200.63
137_A159_F0.6190.62
128_A166_L0.6190.62
158_H164_L0.6150.62
114_S117_G0.6150.62
32_R127_D0.6110.61
160_F164_L0.6070.61
71_L74_S0.6070.61
8_E31_S0.6060.61
158_H163_L0.6050.61
105_R169_M0.6030.60
18_L61_I0.6030.60
134_I164_L0.6020.60
41_G119_A0.5990.60
81_V90_A0.5990.60
80_L93_V0.5960.60
12_T177_E0.5950.59
167_K179_A0.5920.59
8_E12_T0.5910.59
46_A116_E0.5870.58
96_I99_R0.5840.58
28_H151_D0.5830.58
105_R112_P0.5820.58
138_F141_A0.5800.58
79_Q82_F0.5790.57
63_V105_R0.5790.57
14_V30_V0.5770.57
39_Y92_R0.5730.57
191_R195_K0.5720.56
34_A55_A0.5720.56
13_W82_F0.5710.56
115_I119_A0.5690.56
84_G173_D0.5680.56
22_S139_M0.5670.56
53_T89_N0.5670.56
14_V17_I0.5650.56
135_A142_G0.5640.55
25_H128_A0.5640.55
174_T178_L0.5630.55
125_R171_N0.5630.55
16_S19_T0.5610.55
104_D110_K0.5560.54
57_V193_L0.5550.54
98_T110_K0.5550.54
62_D125_R0.5530.54
54_A120_V0.5510.54
42_E74_S0.5490.53
7_A11_R0.5490.53
141_A157_A0.5480.53
137_A166_L0.5460.53
35_D198_P0.5440.53
62_D120_V0.5430.53
117_G139_M0.5380.52
103_R125_R0.5380.52
35_D38_A0.5370.52
151_D157_A0.5360.52
95_H98_T0.5340.51
40_I120_V0.5340.51
70_R74_S0.5340.51
70_R98_T0.5310.51
38_A48_L0.5310.51
17_I20_D0.5300.51
64_K161_H0.5260.50
158_H161_H0.5260.50
78_D81_V0.5250.50
8_E16_S0.5180.49
95_H117_G0.5180.49
117_G171_N0.5150.49
149_Y197_I0.5080.48
129_I179_A0.5060.48
16_S20_D0.5050.48
8_E88_E0.5040.47
138_F181_E0.5040.47
44_E119_A0.5030.47
141_A150_G0.5010.47
181_E184_N0.5010.47
62_D140_F0.5010.47
114_S118_K0.5000.47
14_V56_L0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2pjqA 2 0.9561 100 0.283 Contact Map
2qgsA 2 0.9415 100 0.287 Contact Map
3b57A 2 0.8683 100 0.291 Contact Map
3dtoA 2 0.8537 100 0.295 Contact Map
3djbA 2 0.8976 100 0.298 Contact Map
3gw7A 2 0.9073 100 0.299 Contact Map
2pq7A 2 0.7902 100 0.336 Contact Map
2hekA 4 0.8829 99.6 0.751 Contact Map
2q14A 4 0.9024 99.6 0.754 Contact Map
2cqzA 5 0.7854 99.5 0.76 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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