GREMLIN Database
UGTP - Processive diacylglycerol beta-glucosyltransferase
UniProt: P54166 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 382 (338)
Sequences: 20267 (16137)
Seq/√Len: 877.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
313_F319_A3.1431.00
28_Q31_R2.9891.00
344_R347_K2.9251.00
281_P298_L2.8471.00
32_L363_E2.5701.00
342_L346_K2.5181.00
97_G125_G2.4561.00
298_L310_A2.3941.00
297_I335_L2.3671.00
329_L333_T2.3601.00
311_N315_D2.3321.00
320_I334_S2.3201.00
314_E321_V2.3141.00
334_S341_T2.3101.00
50_V54_T2.3021.00
28_Q32_L2.2841.00
101_D126_R2.2751.00
334_S338_D2.2511.00
7_V35_Q2.2051.00
28_Q359_E2.1911.00
202_K232_Q2.1821.00
98_E102_E2.1491.00
344_R348_N2.1441.00
277_M289_A2.1341.00
356_N360_V2.1111.00
10_L26_Y2.0981.00
349_I353_H2.0771.00
333_T337_A2.0761.00
343_H347_K2.0671.00
327_E331_S2.0551.00
215_L219_K2.0531.00
40_S103_H2.0511.00
244_K248_S2.0401.00
320_I331_S1.9641.00
348_N351_D1.9511.00
339_E343_H1.9271.00
97_G126_R1.9221.00
228_D329_L1.9201.00
356_N359_E1.9111.00
289_A296_V1.9081.00
173_K364_D1.8341.00
140_H144_V1.8321.00
110_N130_T1.8161.00
341_T344_R1.7881.00
150_K154_A1.7541.00
266_R269_E1.7541.00
7_V40_S1.7461.00
216_K220_E1.7461.00
277_M285_T1.7401.00
40_S61_S1.7281.00
331_S334_S1.7201.00
51_S55_Q1.7111.00
279_T296_V1.6951.00
345_M348_N1.6731.00
244_K247_L1.6671.00
204_V232_Q1.6661.00
286_L313_F1.6601.00
232_Q259_K1.6381.00
276_C335_L1.6341.00
199_S232_Q1.6111.00
304_G307_K1.6041.00
359_E363_E1.5691.00
139_L142_I1.5371.00
347_K351_D1.5371.00
320_I341_T1.5261.00
346_K349_I1.5151.00
88_Y92_G1.5131.00
255_G258_L1.5051.00
261_L264_V1.5031.00
205_L278_I1.4981.00
151_Y154_A1.4961.00
338_D341_T1.4861.00
311_N314_E1.4851.00
206_L274_T1.4811.00
360_V363_E1.4791.00
190_G194_K1.4591.00
276_C332_V1.4541.00
277_M294_V1.4541.00
95_R98_E1.4511.00
153_V156_D1.4421.00
297_I331_S1.4411.00
139_L143_W1.4381.00
219_K223_E1.4381.00
247_L250_L1.4191.00
32_L362_L1.4091.00
158_V161_K1.4051.00
340_D343_H1.3901.00
9_I42_L1.3851.00
138_C141_K1.3791.00
8_L107_I1.3771.00
341_T345_M1.3491.00
139_L144_V1.3441.00
8_L29_C1.3441.00
203_K275_D1.3401.00
28_Q358_S1.3351.00
217_N221_L1.3351.00
97_G101_D1.3251.00
340_D344_R1.3221.00
220_E223_E1.3211.00
348_N352_L1.3141.00
108_I123_R1.2901.00
150_K155_T1.2881.00
269_E272_R1.2801.00
150_K173_K1.2781.00
109_I131_F1.2741.00
205_L276_C1.2731.00
141_K144_V1.2651.00
8_L34_F1.2621.00
327_E330_E1.2611.00
217_N225_L1.2581.00
312_F315_D1.2481.00
150_K153_V1.2471.00
222_C225_L1.2451.00
150_K156_D1.2421.00
200_P232_Q1.2331.00
313_F318_A1.2261.00
28_Q362_L1.2221.00
330_E334_S1.2191.00
27_E30_V1.2161.00
358_S362_L1.2151.00
229_D333_T1.2051.00
159_K162_L1.2021.00
220_E224_N1.1961.00
131_F152_Y1.1961.00
29_C362_L1.1921.00
193_Y197_N1.1911.00
120_Y130_T1.1861.00
360_V364_D1.1821.00
245_E248_S1.1721.00
74_Y77_D1.1551.00
314_E320_I1.1541.00
147_N151_Y1.1521.00
271_F292_I1.1501.00
218_V222_C1.1501.00
17_G21_V1.1491.00
131_F365_I1.1411.00
347_K350_K1.1401.00
318_A348_N1.1381.00
246_S250_L1.1351.00
50_V60_K1.1341.00
140_H143_W1.1301.00
326_E330_E1.1221.00
341_T348_N1.1211.00
57_L60_K1.1111.00
98_E101_D1.1101.00
202_K230_Q1.1071.00
215_L218_V1.1031.00
239_K262_G1.1011.00
122_R126_R1.0991.00
59_L62_F1.0951.00
339_E342_L1.0931.00
231_V333_T1.0921.00
192_I195_K1.0891.00
320_I335_L1.0861.00
57_L61_S1.0791.00
148_V152_Y1.0761.00
107_I131_F1.0711.00
74_Y78_K1.0691.00
350_K354_L1.0691.00
138_C142_I1.0691.00
307_K311_N1.0681.00
86_N90_K1.0681.00
322_V331_S1.0661.00
51_S54_T1.0611.00
30_V39_V1.0581.00
9_I105_P1.0581.00
94_K98_E1.0571.00
206_L236_V1.0561.00
10_L22_A1.0551.00
32_L359_E1.0541.00
25_L361_I1.0461.00
152_Y361_I1.0361.00
205_L233_V1.0361.00
10_L109_I1.0361.00
20_Q263_Y1.0331.00
236_V264_V1.0291.00
245_E249_A1.0261.00
354_L360_V1.0221.00
204_V274_T1.0211.00
207_I233_V1.0211.00
290_T318_A1.0151.00
73_Y76_V1.0141.00
149_D153_V1.0091.00
342_L348_N1.0061.00
83_R86_N1.0011.00
293_G350_K1.0001.00
228_D333_T0.9991.00
246_S249_A0.9991.00
16_N20_Q0.9991.00
297_I320_I0.9971.00
152_Y364_D0.9961.00
217_N220_E0.9951.00
138_C144_V0.9941.00
234_V270_L0.9901.00
350_K353_H0.9891.00
149_D155_T0.9851.00
191_P194_K0.9851.00
222_C226_V0.9841.00
138_C143_W0.9771.00
52_E55_Q0.9721.00
343_H346_K0.9691.00
218_V225_L0.9651.00
278_I299_Y0.9611.00
217_N223_E0.9591.00
346_K350_K0.9571.00
223_E226_V0.9561.00
147_N150_K0.9561.00
175_T178_P0.9531.00
82_K86_N0.9491.00
123_R130_T0.9471.00
152_Y155_T0.9421.00
70_R74_Y0.9401.00
190_G193_Y0.9341.00
312_F316_R0.9251.00
57_L62_F0.9221.00
35_Q59_L0.9211.00
61_S102_E0.9181.00
45_E62_F0.9161.00
115_I118_P0.9141.00
193_Y273_I0.9121.00
298_L313_F0.9111.00
124_T147_N0.9081.00
307_K323_N0.9081.00
148_V155_T0.9071.00
27_E31_R0.9051.00
151_Y156_D0.9041.00
180_R183_F0.9031.00
335_L341_T0.9001.00
158_V162_L0.9001.00
53_V58_Y0.9001.00
80_Y83_R0.8961.00
150_K364_D0.8961.00
317_G344_R0.8911.00
204_V234_V0.8911.00
217_N224_N0.8901.00
9_I100_V0.8831.00
15_G212_H0.8811.00
151_Y155_T0.8801.00
173_K176_G0.8801.00
96_L100_V0.8781.00
84_K88_Y0.8781.00
56_Y61_S0.8771.00
44_Q47_N0.8671.00
76_V79_I0.8671.00
320_I323_N0.8671.00
27_E58_Y0.8651.00
156_D159_K0.8621.00
58_Y61_S0.8601.00
84_K87_I0.8521.00
311_N321_V0.8511.00
159_K169_P0.8471.00
85_F89_F0.8441.00
206_L266_R0.8401.00
191_P195_K0.8391.00
152_Y175_T0.8371.00
218_V221_L0.8361.00
278_I328_I0.8321.00
286_L309_N0.8321.00
22_A41_N0.8291.00
342_L349_I0.8291.00
296_V319_A0.8291.00
27_E56_Y0.8261.00
298_L319_A0.8261.00
263_Y266_R0.8251.00
203_K336_L0.8251.00
341_T349_I0.8221.00
110_N119_E0.8201.00
108_I128_I0.8141.00
94_K97_G0.8121.00
342_L345_M0.8111.00
149_D154_A0.8091.00
254_N258_L0.8071.00
145_H151_Y0.8061.00
148_V154_A0.8051.00
69_Y73_Y0.8041.00
235_V238_G0.8031.00
72_F76_V0.8021.00
71_L76_V0.8011.00
152_Y156_D0.7981.00
72_F75_G0.7971.00
217_N222_C0.7911.00
213_G302_V0.7901.00
293_G349_I0.7891.00
296_V313_F0.7881.00
208_M267_I0.7881.00
310_A321_V0.7871.00
198_L232_Q0.7861.00
217_N226_V0.7841.00
88_Y91_M0.7821.00
216_K219_K0.7801.00
244_K262_G0.7781.00
244_K250_L0.7771.00
293_G345_M0.7761.00
219_K225_L0.7761.00
228_D337_A0.7751.00
25_L358_S0.7721.00
26_Y58_Y0.7721.00
80_Y84_K0.7721.00
171_N175_T0.7661.00
221_L225_L0.7641.00
281_P310_A0.7581.00
87_I91_M0.7581.00
18_H111_T0.7581.00
75_G78_K0.7571.00
267_I271_F0.7571.00
268_D271_F0.7531.00
148_V151_Y0.7521.00
286_L296_V0.7521.00
99_L102_E0.7521.00
345_M349_I0.7511.00
218_V223_E0.7471.00
234_V259_K0.7461.00
349_I352_L0.7461.00
174_I177_I0.7461.00
205_L231_V0.7441.00
7_V103_H0.7441.00
75_G79_I0.7431.00
73_Y77_D0.7431.00
30_V58_Y0.7431.00
24_T27_E0.7391.00
54_T59_L0.7371.00
147_N154_A0.7371.00
71_L74_Y0.7371.00
147_N155_T0.7361.00
21_V284_I0.7331.00
274_T294_V0.7301.00
206_L270_L0.7301.00
250_L255_G0.7301.00
254_N257_K0.7281.00
279_T285_T0.7261.00
317_G348_N0.7251.00
69_Y76_V0.7221.00
308_E311_N0.7211.00
355_A360_V0.7211.00
80_Y88_Y0.7171.00
23_K27_E0.7161.00
222_C235_V0.7101.00
362_L365_I0.7101.00
95_R100_V0.7071.00
29_C34_F0.7021.00
27_E182_Q0.7021.00
206_L271_F0.6991.00
10_L29_C0.6961.00
149_D152_Y0.6961.00
146_E149_D0.6961.00
168_H171_N0.6951.00
70_R73_Y0.6951.00
54_T60_K0.6931.00
58_Y63_S0.6891.00
221_L226_V0.6891.00
129_P149_D0.6871.00
294_V342_L0.6861.00
223_E250_L0.6851.00
58_Y62_F0.6851.00
50_V53_V0.6831.00
82_K85_F0.6821.00
109_I365_I0.6811.00
12_A22_A0.6801.00
85_F88_Y0.6801.00
226_V233_V0.6781.00
86_N89_F0.6761.00
145_H149_D0.6751.00
269_E273_I0.6721.00
69_Y72_F0.6711.00
241_T244_K0.6701.00
204_V273_I0.6701.00
289_A298_L0.6691.00
306_E309_N0.6671.00
54_T57_L0.6651.00
219_K224_N0.6641.00
203_K339_E0.6641.00
47_N50_V0.6631.00
89_F92_G0.6581.00
131_F150_K0.6581.00
194_K198_L0.6571.00
53_V57_L0.6501.00
71_L78_K0.6501.00
7_V106_D0.6491.00
194_K197_N0.6481.00
203_K230_Q0.6481.00
181_P185_E0.6431.00
195_K232_Q0.6421.00
71_L77_D0.6421.00
192_I196_Y0.6411.00
53_V56_Y0.6381.00
70_R75_G0.6361.00
53_V60_K0.6341.00
231_V336_L0.6311.00
40_S59_L0.6301.00
217_N324_R0.6261.00
180_R184_E0.6231.00
146_E150_K0.6231.00
107_I365_I0.6221.00
166_G169_P0.6221.00
173_K177_I0.6201.00
35_Q40_S0.6191.00
195_K259_K0.6161.00
147_N153_V0.6161.00
264_V270_L0.6151.00
99_L103_H0.6141.00
221_L224_N0.6111.00
330_E333_T0.6091.00
199_S202_K0.6081.00
276_C342_L0.6081.00
272_R292_I0.6081.00
148_V156_D0.6071.00
215_L222_C0.6061.00
231_V337_A0.6061.00
208_M285_T0.6051.00
219_K222_C0.6041.00
301_P306_E0.6031.00
45_E50_V0.6031.00
145_H150_K0.6031.00
34_F106_D0.6021.00
24_T180_R0.6021.00
230_Q333_T0.6011.00
173_K360_V0.6011.00
153_V159_K0.6001.00
179_I182_Q0.6001.00
81_N84_K0.5971.00
154_A158_V0.5961.00
22_A111_T0.5961.00
55_Q58_Y0.5911.00
147_N152_Y0.5911.00
122_R125_G0.5901.00
50_V55_Q0.5831.00
100_V126_R0.5821.00
145_H148_V0.5811.00
124_T127_V0.5791.00
203_K231_V0.5791.00
69_Y75_G0.5791.00
280_K306_E0.5791.00
42_L96_L0.5781.00
11_T119_E0.5771.00
120_Y124_T0.5771.00
70_R76_V0.5761.00
148_V153_V0.5731.00
203_K232_Q0.5721.00
26_Y41_N0.5721.00
43_Y47_N0.5711.00
82_K88_Y0.5711.00
89_F95_R0.5701.00
179_I291_A0.5701.00
156_D160_E0.5681.00
87_I92_G0.5681.00
291_A353_H0.5681.00
55_Q265_E0.5641.00
235_V258_L0.5631.00
358_S361_I0.5621.00
265_E268_D0.5621.00
290_T345_M0.5621.00
31_R181_P0.5611.00
271_F277_M0.5601.00
219_K246_S0.5591.00
208_M277_M0.5581.00
149_D156_D0.5581.00
225_L233_V0.5561.00
197_N273_I0.5531.00
224_N328_I0.5531.00
73_Y78_K0.5501.00
71_L75_G0.5481.00
150_K157_Y0.5461.00
56_Y59_L0.5461.00
153_V158_V0.5451.00
290_T313_F0.5441.00
218_V226_V0.5431.00
201_N204_V0.5401.00
91_M95_R0.5381.00
56_Y62_F0.5351.00
26_Y39_V0.5341.00
51_S56_Y0.5331.00
229_D233_V0.5321.00
278_I332_V0.5321.00
204_V275_D0.5321.00
70_R77_D0.5311.00
175_T361_I0.5311.00
310_A314_E0.5301.00
94_K100_V0.5291.00
69_Y77_D0.5291.00
56_Y60_K0.5271.00
244_K249_A0.5251.00
61_S103_H0.5241.00
25_L111_T0.5241.00
121_R125_G0.5241.00
104_Q128_I0.5231.00
159_K174_I0.5201.00
72_F78_K0.5151.00
293_G346_K0.5141.00
101_D125_G0.5121.00
31_R359_E0.5091.00
266_R288_E0.5081.00
218_V237_C0.5081.00
226_V257_K0.5081.00
132_N148_V0.5071.00
34_F39_V0.5071.00
153_V174_I0.5061.00
230_Q257_K0.5061.00
43_Y46_S0.5051.00
25_L178_P0.5041.00
84_K92_G0.5031.00
82_K90_K0.5021.00
29_C39_V0.5011.00
206_L264_V0.5011.00
206_L277_M0.5011.00
193_Y199_S0.5001.00
53_V62_F0.5001.00
225_L329_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2iyaA 1 0.8953 100 0.376 Contact Map
2pq6A 1 0.8717 100 0.381 Contact Map
2c1xA 1 0.9162 100 0.382 Contact Map
2vchA 1 0.9293 100 0.385 Contact Map
3hbfA 1 0.9346 100 0.39 Contact Map
3rscA 1 0.8979 100 0.391 Contact Map
2iyfA 1 0.8953 100 0.395 Contact Map
3ia7A 2 0.9005 100 0.402 Contact Map
2p6pA 2 0.8901 100 0.403 Contact Map
2acvA 1 0.9319 100 0.404 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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