SMC - BACSU - GREMLIN Contacts

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SMC - Chromosome partition protein Smc

UniProt:	P51834	Sequences: MFLKRLDVIGFKSFAERISVDFVKGVTAVVGPNGSGKSNITDAIRWVLGEQSARSLRGGKMEDIIFAGSDSRKRLNLAEVTLTLDNDDHFLPIDFHEVSVTRRVYRSGESEFLINNQPCRLKDIIDLFMDSGLGKEAFSIISQGKVEEILSSKAEDRRSIFEEAAGVLKYKTRKKKAENKLFETQDNLNRVEDILHELEGQVEPLKIQASIAKDYLEKKKELEHVEIALTAYDIEELHGKWSTLKEKVQMAKEEELAESSAISAKEAKIEDTRDKIQALDESVDELQQVLLVTSEELEKLEGRKEVLKERKKNAVQNQEQLEEAIVQFQQKETVLKEELSKQEAVFETLQAEVKQLRAQVKEKQQALSLHNENVEEKIEQLKSDYFELLNSQASIRNELQLLDDQMSQSAVTLQRLADNNEKHLQERHDISARKAACETEFARIEQEIHSQVGAYRDMQTKYEQKKRQYEKNESALYQAYQYVQQARSKKDMLETMQGDFSGFYQGVKEVLKAKERLGGIRGAVLELISTEQKYETAIEIALGASAQHVVTDDEQSARKAIQYLKQNSFGRATFLPLSVIRDRQLQSRDAETAARHSSFLGVASELVTFDPAYRSVIQNLLGTVLITEDLKGANELAKLLGHRYRIVTLEGDVVNPGGSMTGGAVKKKNNSLLGRSRELEDVTKRLAEMEEKTALLEQEVKTLKHSIQDMEKKLADLRETGEGLRLKQQDVKGQLYELQVAEKNINTHLELYDQEKSALSESDEERKVRKRKLEEELSAVSEKMKQLEEDIDRLTKQKQTQSSTKESLSNELTELKIAAAKKEQACKGEEDNLARLKKELTETELALKEAKEDLSFLTSEMSSSTSGEEKLEEAAKHKLNDKTKTIELIALRRDQRIKLQHGLDTYERELKEMKRLYKQKTTLLKDEEVKLGRMEVELDNLLQYLREEYSLSFEGAKEKYQLETDPEEARKRVKLIKLAIEELGTVNLGSIDEFERVNERYKFLSEQKEDLTEAKNTLFQVIEEMDEEMTKRFNDTFVQIRSHFDQVFRSLFGGGRAELRLTDPNDLLHSGVEIIAQPPGKKLQNLNLLSGGERALTAIALLFSILKVRPVPFCVLDEVEAALDEANVFRFAQYLKKYSSDTQFIVITHRKGTMEEADVLYGVTMQESGVSKVISVKLEETKEFVQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	1186 (1166)
Sequences:	2992 (2450)
Seq/√Len:	71.8

BACSU - SMC SBCC
HALSA - Q9HS95

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
629_D	632_G	5.296	1.00
1050_S	1137_K	4.403	1.00
81_T	99_S	4.227	1.00
222_L	973_V	4.042	1.00
527_L	550_V	3.492	1.00
998_N	1002_K	3.426	1.00
221_E	972_R	3.336	1.00
1034_N	1038_V	3.253	1.00
614_R	618_Q	3.199	1.00
4_K	97_E	3.168	1.00
341_K	345_V	3.138	1.00
553_D	556_S	3.102	1.00
81_T	101_T	3.075	1.00
760_S	764_E	3.075	1.00
848_K	851_K	3.055	1.00
627_T	646_I	2.971	1.00
628_E	632_G	2.892	1.00
874_A	877_H	2.885	1.00
891_L	895_Q	2.862	1.00
688_E	692_K	2.851	1.00
837_K	841_T	2.850	1.00
529_S	608_T	2.826	1.00
468_Q	471_K	2.816	1.00
715_A	718_R	2.793	1.00
552_D	556_S	2.785	1.00
867_G	870_K	2.735	1.00
1056_R	1077_Q	2.729	1.00
611_P	614_R	2.703	1.00
972_R	975_L	2.646	1.00
944_Y	948_E	2.592	1.00
965_D	968_E	2.576	1.00
770_K	774_E	2.555	1.00
812_L	816_K	2.550	1.00
806_E	809_S	2.528	1.00
242_S	246_E	2.505	1.00
832_N	835_R	2.469	1.00
44_I	1115_V	2.468	1.00
450_S	454_A	2.455	1.00
772_K	776_E	2.428	1.00
898_K	902_G	2.414	1.00
685_R	688_E	2.399	1.00
358_A	362_E	2.376	1.00
855_S	859_S	2.361	1.00
442_A	445_E	2.360	1.00
264_A	268_K	2.349	1.00
681_D	685_R	2.348	1.00
562_Q	566_Q	2.325	1.00
1009_E	1013_E	2.323	1.00
100_V	128_F	2.299	1.00
538_I	603_A	2.297	1.00
229_L	966_P	2.291	1.00
355_Q	359_Q	2.283	1.00
434_K	735_L	2.278	1.00
554_E	578_S	2.272	1.00
225_V	969_A	2.267	1.00
379_E	382_K	2.262	1.00
357_R	361_K	2.259	1.00
900_Q	904_D	2.255	1.00
302_G	306_V	2.249	1.00
775_E	779_A	2.249	1.00
335_L	339_L	2.242	1.00
835_R	839_E	2.232	1.00
741_A	744_N	2.224	1.00
476_L	479_A	2.224	1.00
490_K	679_L	2.214	1.00
849_E	853_D	2.208	1.00
771_R	775_E	2.207	1.00
807_S	811_E	2.200	1.00
577_L	616_V	2.188	1.00
453_G	457_D	2.184	1.00
742_E	746_N	2.176	1.00
344_A	348_T	2.175	1.00
503_F	507_V	2.155	1.00
1066_D	1069_H	2.155	1.00
457_D	461_K	2.134	1.00
805_K	812_L	2.133	1.00
994_F	998_N	2.116	1.00
79_E	103_R	2.100	1.00
722_E	725_R	2.094	1.00
758_A	762_S	2.087	1.00
887_E	891_L	2.083	1.00
727_K	730_D	2.080	1.00
446_Q	450_S	2.076	1.00
348_T	352_E	2.063	1.00
607_V	621_L	2.062	1.00
5_R	19_S	2.059	1.00
243_T	247_K	2.059	1.00
245_K	249_Q	2.042	1.00
333_T	336_K	2.041	1.00
844_E	848_K	2.040	1.00
783_K	786_Q	2.039	1.00
761_E	765_E	2.038	1.00
203_E	206_K	2.034	1.00
475_A	478_Q	2.019	1.00
813_T	816_K	2.015	1.00
723_G	726_L	2.007	1.00
805_K	809_S	2.006	1.00
779_A	783_K	1.998	1.00
697_E	704_K	1.995	1.00
602_V	605_E	1.993	1.00
708_Q	711_E	1.987	1.00
769_R	772_K	1.951	1.00
271_D	275_K	1.946	1.00
630_L	654_V	1.944	1.00
702_T	706_S	1.939	1.00
509_E	513_A	1.938	1.00
414_Q	417_A	1.932	1.00
720_T	723_G	1.929	1.00
428_H	431_S	1.928	1.00
730_D	734_Q	1.926	1.00
842_E	846_A	1.925	1.00
855_S	858_T	1.925	1.00
483_V	686_L	1.921	1.00
507_V	511_L	1.921	1.00
885_T	888_L	1.906	1.00
464_Q	468_Q	1.903	1.00
528_I	617_I	1.892	1.00
877_H	881_D	1.890	1.00
250_M	254_E	1.886	1.00
948_E	952_S	1.882	1.00
884_K	887_E	1.877	1.00
330_Q	334_V	1.876	1.00
800_T	804_T	1.874	1.00
4_K	85_D	1.871	1.00
340_S	343_E	1.855	1.00
880_N	884_K	1.854	1.00
723_G	727_K	1.854	1.00
841_T	844_E	1.843	1.00
470_E	473_E	1.834	1.00
945_L	948_E	1.832	1.00
475_A	479_A	1.827	1.00
507_V	510_V	1.827	1.00
748_H	755_E	1.826	1.00
347_E	350_Q	1.819	1.00
350_Q	354_K	1.812	1.00
765_E	769_R	1.804	1.00
848_K	852_E	1.794	1.00
881_D	884_K	1.788	1.00
552_D	612_A	1.787	1.00
827_K	831_D	1.784	1.00
778_S	782_E	1.784	1.00
820_A	824_Q	1.777	1.00
879_L	883_T	1.776	1.00
473_E	477_Y	1.774	1.00
810_N	814_E	1.772	1.00
225_V	972_R	1.767	1.00
257_A	261_A	1.758	1.00
514_K	517_L	1.756	1.00
838_K	841_T	1.753	1.00
945_L	952_S	1.746	1.00
361_K	364_Q	1.742	1.00
771_R	774_E	1.741	1.00
294_S	301_E	1.740	1.00
889_I	893_R	1.738	1.00
609_F	614_R	1.736	1.00
444_I	448_I	1.736	1.00
803_S	807_S	1.736	1.00
813_T	817_I	1.728	1.00
278_A	282_S	1.722	1.00
454_A	457_D	1.720	1.00
860_E	864_S	1.717	1.00
410_A	414_Q	1.712	1.00
493_L	497_Q	1.710	1.00
535_E	677_R	1.709	1.00
687_A	690_E	1.708	1.00
703_L	707_I	1.707	1.00
377_K	380_Q	1.706	1.00
465_K	703_L	1.706	1.00
764_E	768_V	1.704	1.00
726_L	730_D	1.700	1.00
489_K	678_E	1.693	1.00
292_V	296_E	1.687	1.00
692_K	695_L	1.685	1.00
438_E	442_A	1.680	1.00
377_K	381_L	1.679	1.00
1028_E	1032_R	1.675	1.00
443_R	447_E	1.675	1.00
716_D	720_T	1.673	1.00
412_T	419_N	1.671	1.00
320_Q	324_A	1.671	1.00
791_I	798_K	1.671	1.00
489_K	493_L	1.670	1.00
83_T	99_S	1.670	1.00
786_Q	790_D	1.666	1.00
147_E	150_L	1.663	1.00
682_V	686_L	1.661	1.00
949_Y	952_S	1.657	1.00
872_E	876_K	1.657	1.00
206_K	994_F	1.656	1.00
449_H	452_V	1.656	1.00
606_L	626_I	1.656	1.00
684_K	688_E	1.656	1.00
521_R	552_D	1.653	1.00
706_S	709_D	1.652	1.00
114_I	124_I	1.642	0.99
869_E	873_E	1.642	0.99
298_E	302_G	1.639	0.99
328_F	331_K	1.639	0.99
354_K	357_R	1.637	0.99
888_L	892_R	1.636	0.99
746_N	750_E	1.636	0.99
339_L	343_E	1.633	0.99
1041_R	1058_E	1.632	0.99
734_Q	737_E	1.632	0.99
907_E	910_L	1.631	0.99
22_F	1145_I	1.626	0.99
435_A	438_E	1.626	0.99
305_E	308_K	1.625	0.99
467_R	470_E	1.622	0.99
342_Q	345_V	1.621	0.99
893_R	896_R	1.617	0.99
356_L	359_Q	1.615	0.99
503_F	506_G	1.613	0.99
826_C	830_E	1.609	0.99
329_Q	333_T	1.604	0.99
601_G	605_E	1.593	0.99
893_R	897_I	1.590	0.99
671_S	675_R	1.586	0.99
343_E	347_E	1.584	0.99
776_E	779_A	1.579	0.99
256_L	260_S	1.572	0.99
924_L	928_E	1.571	0.99
789_E	793_R	1.568	0.99
332_E	336_K	1.567	0.99
1076_A	1097_T	1.566	0.99
817_I	821_K	1.564	0.99
349_L	352_E	1.555	0.99
455_Y	459_Q	1.555	0.99
533_K	649_L	1.553	0.99
360_V	364_Q	1.553	0.99
916_L	919_Q	1.546	0.99
774_E	781_S	1.546	0.99
1008_K	1012_T	1.544	0.99
713_K	716_D	1.537	0.99
828_G	832_N	1.537	0.99
447_E	450_S	1.536	0.99
1034_N	1067_L	1.536	0.99
878_K	881_D	1.534	0.99
309_E	312_K	1.531	0.99
987_N	990_S	1.529	0.99
275_K	278_A	1.525	0.99
337_E	341_K	1.525	0.99
875_A	879_L	1.522	0.99
853_D	856_F	1.520	0.99
495_T	499_D	1.519	0.99
774_E	778_S	1.519	0.99
254_E	257_A	1.518	0.99
490_K	494_E	1.514	0.99
192_E	1008_K	1.514	0.99
724_L	727_K	1.513	0.99
432_A	436_A	1.511	0.99
815_L	818_A	1.509	0.99
859_S	863_S	1.509	0.99
910_L	914_K	1.504	0.99
362_E	366_A	1.503	0.99
91_L	98_V	1.502	0.99
863_S	867_G	1.499	0.99
714_L	718_R	1.494	0.99
851_K	855_S	1.489	0.99
363_K	366_A	1.488	0.99
373_N	376_E	1.488	0.99
899_L	906_Y	1.487	0.99
886_I	890_A	1.479	0.99
753_D	757_S	1.477	0.99
522_G	527_L	1.475	0.99
931_L	935_E	1.475	0.99
386_F	389_L	1.474	0.99
247_K	250_M	1.474	0.99
827_K	830_E	1.473	0.99
909_E	912_E	1.472	0.99
743_K	746_N	1.471	0.99
743_K	747_T	1.471	0.99
836_L	840_L	1.468	0.99
762_S	765_E	1.467	0.99
696_L	699_E	1.465	0.99
777_L	784_M	1.461	0.99
864_S	871_L	1.460	0.99
325_I	329_Q	1.455	0.99
486_A	490_K	1.454	0.99
691_E	695_L	1.450	0.99
1001_Y	1005_S	1.449	0.99
819_A	822_K	1.447	0.99
833_L	840_L	1.447	0.99
645_R	653_V	1.445	0.99
1002_K	1006_E	1.445	0.99
428_H	432_A	1.443	0.99
506_G	510_V	1.443	0.99
324_A	328_F	1.441	0.99
745_I	752_Y	1.438	0.99
858_T	862_S	1.436	0.99
431_S	746_N	1.436	0.99
1036_T	1040_I	1.426	0.99
1047_V	1051_L	1.426	0.99
352_E	356_L	1.423	0.99
101_T	113_L	1.420	0.99
214_D	218_K	1.418	0.98
834_A	838_K	1.417	0.98
1067_L	1070_S	1.413	0.98
793_R	797_Q	1.413	0.98
482_Y	685_R	1.411	0.98
729_Q	732_K	1.410	0.98
225_V	973_V	1.407	0.98
767_K	771_R	1.400	0.98
218_K	979_A	1.395	0.98
253_E	256_L	1.394	0.98
829_E	832_N	1.393	0.98
435_A	439_T	1.391	0.98
298_E	301_E	1.390	0.98
899_L	902_G	1.390	0.98
217_E	221_E	1.389	0.98
28_A	1157_A	1.389	0.98
429_D	433_R	1.387	0.98
883_T	886_I	1.387	0.98
5_R	83_T	1.387	0.98
703_L	706_S	1.387	0.98
736_Y	740_V	1.387	0.98
434_K	438_E	1.384	0.98
439_T	443_R	1.383	0.98
870_K	874_A	1.378	0.98
206_K	210_S	1.378	0.98
695_L	699_E	1.377	0.98
678_E	682_V	1.376	0.98
892_R	895_Q	1.374	0.98
910_L	917_Y	1.374	0.98
893_R	903_L	1.371	0.98
1086_L	1094_R	1.370	0.98
492_M	496_M	1.370	0.98
1058_E	1075_I	1.369	0.98
459_Q	463_E	1.369	0.98
949_Y	953_F	1.368	0.98
884_K	888_L	1.367	0.98
382_K	386_F	1.362	0.98
541_A	624_V	1.360	0.98
373_N	377_K	1.360	0.98
431_S	435_A	1.359	0.98
147_E	1094_R	1.359	0.98
820_A	823_E	1.354	0.98
197_E	1000_R	1.354	0.98
718_R	722_E	1.352	0.98
239_G	242_S	1.351	0.98
742_E	749_L	1.351	0.98
865_T	869_E	1.349	0.98
7_D	17_R	1.346	0.98
494_E	498_G	1.344	0.98
603_A	626_I	1.343	0.98
625_L	644_Y	1.342	0.98
520_I	549_V	1.341	0.98
381_L	384_D	1.339	0.98
1016_N	1020_Q	1.336	0.98
830_E	834_A	1.336	0.98
1110_P	1114_C	1.334	0.98
785_K	788_E	1.328	0.98
787_L	791_I	1.328	0.98
436_A	440_E	1.327	0.98
337_E	340_S	1.326	0.98
864_S	867_G	1.325	0.98
675_R	679_L	1.324	0.98
747_T	750_E	1.323	0.98
100_V	124_I	1.321	0.98
302_G	309_E	1.321	0.98
882_K	886_I	1.320	0.98
975_L	979_A	1.320	0.98
476_L	693_T	1.317	0.98
802_S	805_K	1.315	0.98
318_Q	322_E	1.313	0.98
869_E	872_E	1.311	0.97
801_Q	805_K	1.310	0.97
502_G	507_V	1.310	0.97
437_C	441_F	1.309	0.97
503_F	511_L	1.309	0.97
902_G	905_T	1.308	0.97
835_R	838_K	1.307	0.97
317_N	320_Q	1.307	0.97
728_Q	732_K	1.307	0.97
326_V	329_Q	1.306	0.97
1081_K	1093_E	1.301	0.97
609_F	617_I	1.300	0.97
817_I	828_G	1.298	0.97
790_D	793_R	1.297	0.97
809_S	812_L	1.295	0.97
764_E	767_K	1.294	0.97
340_S	344_A	1.291	0.97
322_E	326_V	1.288	0.97
603_A	606_L	1.287	0.97
185_Q	1015_K	1.280	0.97
856_F	860_E	1.279	0.97
551_T	557_A	1.279	0.97
394_S	398_E	1.277	0.97
670_N	675_R	1.277	0.97
839_E	842_E	1.274	0.97
424_L	428_H	1.270	0.97
573_T	576_P	1.269	0.97
747_T	751_L	1.268	0.97
733_G	737_E	1.267	0.97
952_S	956_A	1.267	0.97
489_K	497_Q	1.267	0.97
506_G	511_L	1.266	0.97
310_R	313_N	1.266	0.97
553_D	578_S	1.266	0.97
521_R	612_A	1.265	0.97
458_M	710_M	1.264	0.97
915_R	922_T	1.264	0.97
455_Y	714_L	1.263	0.97
477_Y	480_Y	1.262	0.97
923_L	926_D	1.260	0.97
482_Y	485_Q	1.259	0.97
53_A	58_G	1.256	0.97
780_V	783_K	1.255	0.97
897_I	904_D	1.251	0.97
946_R	949_Y	1.247	0.97
319_E	323_E	1.245	0.97
287_Q	291_L	1.243	0.97
401_L	405_Q	1.242	0.96
319_E	322_E	1.240	0.96
873_E	877_H	1.240	0.96
819_A	823_E	1.238	0.96
818_A	822_K	1.237	0.96
506_G	509_E	1.235	0.96
931_L	934_M	1.235	0.96
268_K	271_D	1.234	0.96
750_E	753_D	1.230	0.96
1031_K	1035_D	1.228	0.96
739_Q	743_K	1.227	0.96
503_F	508_K	1.226	0.96
812_L	815_L	1.226	0.96
510_V	514_K	1.223	0.96
680_E	684_K	1.223	0.96
418_D	422_K	1.223	0.96
893_R	900_Q	1.221	0.96
290_L	294_S	1.221	0.96
407_S	410_A	1.221	0.96
968_E	972_R	1.221	0.96
85_D	88_D	1.219	0.96
788_E	791_I	1.218	0.96
808_L	812_L	1.217	0.96
336_K	340_S	1.216	0.96
339_L	346_F	1.216	0.96
816_K	823_E	1.216	0.96
469_Y	700_V	1.215	0.96
766_R	770_K	1.209	0.96
804_T	811_E	1.207	0.96
471_K	475_A	1.204	0.96
911_K	914_K	1.201	0.96
294_S	298_E	1.201	0.96
312_K	316_Q	1.200	0.96
10_G	16_E	1.200	0.96
270_E	274_D	1.197	0.96
829_E	833_L	1.195	0.96
326_V	330_Q	1.195	0.96
828_G	835_R	1.194	0.96
860_E	863_S	1.194	0.96
380_Q	384_D	1.194	0.96
734_Q	738_L	1.194	0.96
867_G	871_L	1.193	0.96
462_Y	707_I	1.192	0.96
790_D	794_L	1.190	0.96
825_A	829_E	1.190	0.96
103_R	113_L	1.189	0.96
261_A	264_A	1.187	0.95
496_M	500_F	1.186	0.95
821_K	828_G	1.183	0.95
672_L	679_L	1.183	0.95
334_V	338_E	1.182	0.95
561_I	574_F	1.181	0.95
451_Q	717_L	1.181	0.95
246_E	249_Q	1.181	0.95
846_A	849_E	1.180	0.95
933_R	937_E	1.179	0.95
841_T	845_L	1.179	0.95
345_V	349_L	1.179	0.95
908_R	911_K	1.179	0.95
471_K	474_S	1.175	0.95
805_K	816_K	1.175	0.95
285_E	289_V	1.175	0.95
333_T	337_E	1.174	0.95
945_L	953_F	1.174	0.95
386_F	390_N	1.173	0.95
489_K	496_M	1.173	0.95
198_L	202_V	1.172	0.95
944_Y	947_E	1.171	0.95
402_L	426_E	1.170	0.95
414_Q	418_D	1.169	0.95
138_F	142_S	1.166	0.95
940_N	943_Q	1.166	0.95
934_M	937_E	1.164	0.95
465_K	468_Q	1.162	0.95
444_I	447_E	1.162	0.95
1015_K	1019_F	1.161	0.95
557_A	662_G	1.161	0.95
904_D	907_E	1.161	0.95
676_S	680_E	1.160	0.95
886_I	893_R	1.160	0.95
896_R	900_Q	1.159	0.95
1098_A	1105_I	1.156	0.95
491_D	495_T	1.154	0.95
1051_L	1100_A	1.153	0.95
478_Q	482_Y	1.152	0.95
892_R	899_L	1.151	0.95
880_N	883_T	1.145	0.94
44_I	48_L	1.144	0.94
845_L	849_E	1.142	0.94
895_Q	898_K	1.142	0.94
926_D	930_K	1.140	0.94
79_E	101_T	1.137	0.94
335_L	342_Q	1.135	0.94
731_V	734_Q	1.135	0.94
306_V	309_E	1.133	0.94
686_L	690_E	1.133	0.94
1023_E	1027_E	1.132	0.94
509_E	514_K	1.129	0.94
226_E	977_K	1.129	0.94
846_A	850_A	1.129	0.94
691_E	694_A	1.126	0.94
715_A	719_E	1.126	0.94
89_H	96_H	1.125	0.94
142_S	145_K	1.124	0.94
421_E	424_L	1.123	0.94
944_Y	952_S	1.122	0.94
422_K	426_E	1.122	0.94
874_A	878_K	1.121	0.94
421_E	425_Q	1.118	0.94
919_Q	923_L	1.118	0.94
178_E	182_F	1.118	0.94
709_D	713_K	1.117	0.94
721_G	725_R	1.117	0.94
455_Y	721_G	1.117	0.94
903_L	910_L	1.116	0.94
381_L	385_Y	1.114	0.94
741_A	745_I	1.113	0.94
808_L	826_C	1.111	0.94
423_H	427_R	1.110	0.94
811_E	814_E	1.107	0.93
305_E	309_E	1.107	0.93
359_Q	362_E	1.106	0.93
833_L	837_K	1.106	0.93
678_E	681_D	1.104	0.93
791_I	795_T	1.104	0.93
846_A	853_D	1.102	0.93
360_V	812_L	1.101	0.93
209_A	213_K	1.098	0.93
862_S	865_T	1.098	0.93
781_S	788_E	1.097	0.93
239_G	243_T	1.096	0.93
246_E	250_M	1.093	0.93
154_A	1071_G	1.093	0.93
948_E	951_L	1.090	0.93
483_V	486_A	1.089	0.93
1043_H	1046_Q	1.088	0.93
210_S	214_D	1.088	0.93
461_K	706_S	1.088	0.93
628_E	649_L	1.087	0.93
762_S	769_R	1.080	0.93
627_T	633_A	1.079	0.93
778_S	781_S	1.079	0.93
383_S	387_E	1.078	0.92
410_A	417_A	1.077	0.92
461_K	464_Q	1.076	0.92
769_R	776_E	1.074	0.92
531_E	608_T	1.073	0.92
302_G	305_E	1.073	0.92
274_D	278_A	1.073	0.92
658_G	662_G	1.072	0.92
822_K	825_A	1.071	0.92
494_E	683_T	1.070	0.92
237_L	241_W	1.069	0.92
745_I	755_E	1.068	0.92
882_K	893_R	1.066	0.92
939_D	943_Q	1.066	0.92
469_Y	476_L	1.066	0.92
875_A	882_K	1.065	0.92
754_Q	758_A	1.065	0.92
755_E	759_L	1.062	0.92
328_F	332_E	1.060	0.92
508_K	511_L	1.059	0.92
474_S	478_Q	1.059	0.92
488_S	496_M	1.059	0.92
1064_P	1070_S	1.057	0.92
913_M	917_Y	1.057	0.92
729_Q	733_G	1.056	0.92
751_L	755_E	1.055	0.92
403_D	410_A	1.055	0.92
806_E	810_N	1.054	0.92
694_A	698_Q	1.054	0.92
717_L	724_L	1.051	0.92
327_Q	331_K	1.051	0.92
1095_A	1122_A	1.048	0.91
349_L	353_V	1.046	0.91
505_Q	509_E	1.043	0.91
212_A	988_L	1.041	0.91
857_L	868_E	1.040	0.91
904_D	910_L	1.040	0.91
284_D	288_Q	1.040	0.91
737_E	740_V	1.039	0.91
269_I	903_L	1.039	0.91
763_D	770_K	1.039	0.91
794_L	797_Q	1.038	0.91
700_V	704_K	1.038	0.91
533_K	628_E	1.036	0.91
1045_D	1058_E	1.035	0.91
400_Q	404_D	1.035	0.91
795_T	798_K	1.035	0.91
509_E	515_E	1.035	0.91
433_R	436_A	1.032	0.91
912_E	916_L	1.032	0.91
454_A	458_M	1.031	0.91
441_F	731_V	1.031	0.91
736_Y	739_Q	1.030	0.91
404_D	407_S	1.030	0.91
42_D	57_R	1.029	0.91
824_Q	827_K	1.029	0.91
316_Q	320_Q	1.028	0.91
259_S	266_E	1.027	0.91
575_L	580_I	1.026	0.91
185_Q	189_N	1.025	0.90
488_S	500_F	1.025	0.90
945_L	950_S	1.024	0.90
689_M	693_T	1.023	0.90
992_D	995_E	1.019	0.90
839_E	843_T	1.016	0.90
440_E	443_R	1.016	0.90
105_Y	108_G	1.016	0.90
711_E	718_R	1.015	0.90
802_S	806_E	1.014	0.90
31_G	36_G	1.013	0.90
120_R	123_D	1.013	0.90
560_A	574_F	1.012	0.90
497_Q	500_F	1.011	0.90
1114_C	1142_T	1.010	0.90
424_L	427_R	1.009	0.90
925_K	929_V	1.008	0.90
755_E	773_L	1.008	0.90
723_G	730_D	1.008	0.90
832_N	846_A	1.007	0.90
1111_V	1120_E	1.007	0.90
114_I	119_C	1.005	0.90
946_R	951_L	1.004	0.90
402_L	409_S	1.004	0.90
1035_D	1039_Q	1.001	0.89
697_E	700_V	1.000	0.89
291_L	294_S	1.000	0.89
482_Y	486_A	0.998	0.89
426_E	429_D	0.997	0.89
707_I	711_E	0.997	0.89
468_Q	699_E	0.996	0.89
297_L	304_K	0.996	0.89
488_S	492_M	0.996	0.89
862_S	866_S	0.996	0.89
888_L	891_L	0.995	0.89
787_L	805_K	0.995	0.89
476_L	480_Y	0.995	0.89
698_Q	702_T	0.992	0.89
413_L	417_A	0.989	0.89
1024_E	1028_E	0.988	0.89
630_L	648_T	0.986	0.89
46_W	64_I	0.986	0.89
490_K	686_L	0.985	0.89
288_Q	292_V	0.985	0.89
536_T	540_I	0.984	0.89
917_Y	924_L	0.983	0.89
1154_M	1160_L	0.982	0.88
945_L	949_Y	0.981	0.88
505_Q	508_K	0.981	0.88
802_S	809_S	0.980	0.88
238_H	242_S	0.980	0.88
31_G	37_K	0.980	0.88
852_E	856_F	0.980	0.88
134_G	139_S	0.980	0.88
804_T	807_S	0.978	0.88
541_A	647_V	0.978	0.88
308_K	312_K	0.977	0.88
706_S	710_M	0.975	0.88
441_F	445_E	0.971	0.88
361_K	365_Q	0.971	0.88
1043_H	1107_K	0.970	0.88
877_H	880_N	0.970	0.88
824_Q	828_G	0.969	0.88
842_E	845_L	0.968	0.88
6_L	22_F	0.968	0.88
907_E	911_K	0.968	0.88
609_F	615_S	0.967	0.88
479_A	482_Y	0.966	0.88
389_L	392_Q	0.965	0.88
563_Y	567_N	0.964	0.88
795_T	799_Q	0.963	0.87
932_G	935_E	0.963	0.87
763_D	767_K	0.963	0.87
766_R	769_R	0.963	0.87
301_E	305_E	0.962	0.87
460_T	463_E	0.961	0.87
489_K	492_M	0.961	0.87
850_A	854_L	0.960	0.87
914_K	924_L	0.957	0.87
440_E	727_K	0.957	0.87
405_Q	408_Q	0.956	0.87
883_T	887_E	0.956	0.87
456_R	460_T	0.955	0.87
825_A	828_G	0.955	0.87
486_A	689_M	0.955	0.87
694_A	697_E	0.955	0.87
296_E	299_K	0.954	0.87
480_Y	697_E	0.951	0.87
201_Q	996_R	0.950	0.87
58_G	63_D	0.949	0.87
448_I	721_G	0.949	0.87
808_L	811_E	0.949	0.87
797_Q	800_T	0.949	0.87
42_D	49_G	0.948	0.87
769_R	773_L	0.947	0.87
794_L	801_Q	0.946	0.87
791_I	805_K	0.944	0.86
655_N	659_S	0.944	0.86
834_A	837_K	0.943	0.86
482_Y	689_M	0.943	0.86
462_Y	466_K	0.940	0.86
927_E	931_L	0.940	0.86
925_K	928_E	0.939	0.86
470_E	474_S	0.939	0.86
901_H	905_T	0.937	0.86
61_M	64_I	0.937	0.86
31_G	34_G	0.935	0.86
83_T	97_E	0.934	0.86
1086_L	1102_L	0.934	0.86
33_N	36_G	0.933	0.86
34_G	37_K	0.933	0.86
823_E	826_C	0.932	0.86
273_R	277_Q	0.931	0.86
821_K	824_Q	0.928	0.85
503_F	509_E	0.927	0.85
395_I	398_E	0.924	0.85
402_L	405_Q	0.922	0.85
12_K	49_G	0.920	0.85
142_S	146_V	0.919	0.85
757_S	761_E	0.919	0.85
5_R	20_V	0.919	0.85
97_E	102_R	0.918	0.85
502_G	506_G	0.917	0.85
521_R	613_Y	0.915	0.85
919_Q	922_T	0.913	0.85
167_V	1029_M	0.912	0.84
952_S	959_K	0.912	0.84
387_E	391_S	0.912	0.84
864_S	875_A	0.911	0.84
252_K	256_L	0.911	0.84
812_L	822_K	0.910	0.84
513_A	516_R	0.910	0.84
504_Y	511_L	0.909	0.84
980_I	983_L	0.909	0.84
898_K	901_H	0.909	0.84
607_V	617_I	0.908	0.84
472_N	475_A	0.908	0.84
679_L	682_V	0.907	0.84
748_H	751_L	0.906	0.84
213_K	995_E	0.906	0.84
149_I	1094_R	0.906	0.84
282_S	286_L	0.905	0.84
735_L	829_E	0.902	0.84
503_F	510_V	0.902	0.84
295_E	298_E	0.900	0.84
33_N	37_K	0.899	0.84
321_L	328_F	0.898	0.84
714_L	721_G	0.898	0.84
929_V	936_V	0.896	0.83
323_E	327_Q	0.896	0.83
155_E	158_R	0.893	0.83
871_L	882_K	0.892	0.83
818_A	821_K	0.892	0.83
787_L	790_D	0.891	0.83
781_S	804_T	0.890	0.83
538_I	606_L	0.890	0.83
809_S	816_K	0.889	0.83
575_L	616_V	0.889	0.83
352_E	355_Q	0.889	0.83
1083_L	1086_L	0.888	0.83
507_V	513_A	0.888	0.83
364_Q	368_S	0.888	0.83
705_H	709_D	0.886	0.83
370_H	373_N	0.885	0.83
309_E	313_N	0.884	0.83
1094_R	1106_L	0.882	0.82
945_L	951_L	0.882	0.82
690_E	694_A	0.880	0.82
796_K	800_T	0.880	0.82
859_S	862_S	0.879	0.82
911_K	915_R	0.878	0.82
871_L	874_A	0.878	0.82
885_T	889_I	0.878	0.82
944_Y	951_L	0.878	0.82
388_L	392_Q	0.877	0.82
524_V	620_L	0.877	0.82
458_M	461_K	0.877	0.82
801_Q	809_S	0.876	0.82
764_E	772_K	0.875	0.82
789_E	792_D	0.875	0.82
921_T	925_K	0.875	0.82
1044_F	1074_I	0.874	0.82
952_S	955_G	0.872	0.82
414_Q	421_E	0.872	0.82
1148_T	1154_M	0.872	0.82
459_Q	718_R	0.871	0.82
710_M	713_K	0.870	0.82
930_K	933_R	0.870	0.82
944_Y	949_Y	0.870	0.82
336_K	343_E	0.870	0.82
835_R	842_E	0.869	0.82
502_G	508_K	0.869	0.82
335_L	353_V	0.868	0.81
882_K	889_I	0.867	0.81
913_M	916_L	0.866	0.81
399_L	403_D	0.866	0.81
598_S	603_A	0.866	0.81
843_T	846_A	0.865	0.81
699_E	703_L	0.864	0.81
190_R	193_D	0.863	0.81
532_Q	535_E	0.863	0.81
951_L	956_A	0.861	0.81
1029_M	1120_E	0.861	0.81
817_I	824_Q	0.860	0.81
46_W	66_F	0.860	0.81
417_A	421_E	0.859	0.81
902_G	906_Y	0.859	0.81
1131_F	1173_V	0.858	0.81
475_A	692_K	0.857	0.81
260_S	264_A	0.856	0.81
446_Q	449_H	0.856	0.81
676_S	682_V	0.856	0.81
788_E	792_D	0.855	0.80
701_K	704_K	0.855	0.80
16_E	72_R	0.855	0.80
720_T	724_L	0.855	0.80
879_L	886_I	0.851	0.80
915_R	918_K	0.851	0.80
420_N	424_L	0.850	0.80
548_H	571_R	0.850	0.80
876_K	879_L	0.849	0.80
329_Q	334_V	0.848	0.80
704_K	708_Q	0.848	0.80
379_E	393_A	0.847	0.80
1046_Q	1107_K	0.847	0.80
812_L	819_A	0.846	0.80
220_K	224_H	0.846	0.80
395_I	399_L	0.846	0.80
400_Q	403_D	0.845	0.80
702_T	705_H	0.844	0.80
570_G	662_G	0.844	0.80
866_S	883_T	0.844	0.80
673_L	676_S	0.844	0.80
674_G	678_E	0.844	0.80
813_T	820_A	0.843	0.80
441_F	444_I	0.842	0.79
872_E	875_A	0.842	0.79
382_K	390_N	0.842	0.79
289_V	292_V	0.841	0.79
219_K	1076_A	0.840	0.79
648_T	654_V	0.840	0.79
1007_Q	1010_D	0.840	0.79
799_Q	802_S	0.840	0.79
1005_S	1009_E	0.839	0.79
922_T	926_D	0.838	0.79
882_K	907_E	0.837	0.79
907_E	914_K	0.836	0.79
886_I	889_I	0.836	0.79
147_E	151_S	0.835	0.79
461_K	465_K	0.835	0.79
382_K	385_Y	0.835	0.79
408_Q	412_T	0.834	0.79
731_V	735_L	0.834	0.79
894_D	898_K	0.834	0.79
699_E	702_T	0.834	0.79
786_Q	789_E	0.834	0.79
953_F	956_A	0.833	0.79
820_A	827_K	0.833	0.79
914_K	921_T	0.832	0.79
768_V	771_R	0.831	0.79
335_L	343_E	0.831	0.79
347_E	351_A	0.830	0.78
233_D	970_R	0.828	0.78
882_K	897_I	0.828	0.78
909_E	913_M	0.828	0.78
128_F	146_V	0.827	0.78
744_N	748_H	0.827	0.78
995_E	999_E	0.825	0.78
841_T	852_E	0.824	0.78
707_I	714_L	0.824	0.78
322_E	858_T	0.824	0.78
762_S	766_R	0.823	0.78
882_K	896_R	0.822	0.78
735_L	739_Q	0.821	0.78
953_F	957_K	0.820	0.78
174_K	177_A	0.819	0.78
1088_L	1106_L	0.819	0.78
451_Q	454_A	0.818	0.77
3_L	82_L	0.817	0.77
137_A	1111_V	0.817	0.77
809_S	821_K	0.817	0.77
306_V	313_N	0.817	0.77
437_C	440_E	0.816	0.77
249_Q	252_K	0.816	0.77
210_S	213_K	0.816	0.77
907_E	922_T	0.815	0.77
153_K	156_D	0.815	0.77
385_Y	389_L	0.814	0.77
899_L	903_L	0.814	0.77
978_L	982_E	0.813	0.77
491_D	498_G	0.813	0.77
148_E	156_D	0.812	0.77
920_K	924_L	0.812	0.77
941_L	948_E	0.811	0.77
722_E	726_L	0.811	0.77
331_K	334_V	0.810	0.77
908_R	915_R	0.808	0.77
922_T	927_E	0.808	0.77
374_V	378_I	0.806	0.76
480_Y	484_Q	0.806	0.76
244_L	247_K	0.806	0.76
847_L	850_A	0.805	0.76
496_M	502_G	0.805	0.76
936_V	943_Q	0.805	0.76
510_V	513_A	0.804	0.76
95_F	117_Q	0.804	0.76
801_Q	812_L	0.803	0.76
894_D	897_I	0.803	0.76
782_E	786_Q	0.802	0.76
338_E	341_K	0.802	0.76
905_T	909_E	0.802	0.76
378_I	381_L	0.801	0.76
487_R	690_E	0.801	0.76
801_Q	808_L	0.799	0.76
393_A	401_L	0.798	0.76
1048_F	1051_L	0.798	0.76
1078_P	1081_K	0.797	0.76
375_E	379_E	0.796	0.75
730_D	733_G	0.796	0.75
1103_F	1162_G	0.796	0.75
677_R	680_E	0.795	0.75
816_K	820_A	0.795	0.75
1050_S	1133_Q	0.794	0.75
448_I	455_Y	0.793	0.75
725_R	729_Q	0.793	0.75
882_K	911_K	0.792	0.75
934_M	938_L	0.792	0.75
138_F	146_V	0.791	0.75
86_N	131_S	0.791	0.75
683_T	690_E	0.790	0.75
840_L	844_E	0.789	0.75
405_Q	412_T	0.789	0.75
427_R	430_I	0.788	0.75
712_K	716_D	0.788	0.75
367_L	371_N	0.788	0.75
1128_V	1152_G	0.788	0.75
1003_F	1007_Q	0.787	0.75
673_L	677_R	0.787	0.75
915_R	919_Q	0.787	0.75
41_T	142_S	0.785	0.74
708_Q	712_K	0.785	0.74
928_E	933_R	0.785	0.74
814_E	817_I	0.784	0.74
675_R	682_V	0.784	0.74
792_D	795_T	0.782	0.74
843_T	847_L	0.780	0.74
727_K	734_Q	0.779	0.74
564_L	574_F	0.778	0.74
1055_G	1078_P	0.778	0.74
392_Q	396_R	0.778	0.74
670_N	676_S	0.776	0.74
388_L	391_S	0.776	0.74
12_K	39_N	0.775	0.74
332_E	840_L	0.775	0.74
1166_Q	1172_K	0.774	0.73
732_K	736_Y	0.774	0.73
1055_G	1061_L	0.774	0.73
923_L	927_E	0.773	0.73
738_L	741_A	0.773	0.73
831_D	838_K	0.773	0.73
167_V	170_Y	0.773	0.73
908_R	912_E	0.772	0.73
253_E	257_A	0.771	0.73
938_L	948_E	0.771	0.73
266_E	273_R	0.770	0.73
331_K	338_E	0.770	0.73
522_G	662_G	0.770	0.73
248_V	924_L	0.770	0.73
749_L	769_R	0.769	0.73
784_M	791_I	0.769	0.73
371_N	375_E	0.768	0.73
376_E	380_Q	0.768	0.73
445_E	449_H	0.767	0.73
769_R	780_V	0.767	0.73
1102_L	1120_E	0.766	0.73
299_K	302_G	0.765	0.73
1052_F	1149_H	0.765	0.73
897_I	915_R	0.763	0.72
100_V	133_L	0.763	0.72
937_E	940_N	0.763	0.72
119_C	124_I	0.762	0.72
362_E	365_Q	0.761	0.72
1132_A	1152_G	0.761	0.72
647_V	653_V	0.760	0.72
139_S	1111_V	0.760	0.72
924_L	938_L	0.760	0.72
292_V	295_E	0.760	0.72
749_L	753_D	0.759	0.72
767_K	770_K	0.759	0.72
65_I	106_R	0.758	0.72
774_E	777_L	0.758	0.72
35_S	1150_R	0.756	0.72
61_M	65_I	0.755	0.72
601_G	606_L	0.755	0.72
105_Y	109_E	0.755	0.72
341_K	365_Q	0.755	0.72
543_G	663_G	0.754	0.71
345_V	348_T	0.753	0.71
208_Q	987_N	0.753	0.71
142_S	150_L	0.752	0.71
475_A	699_E	0.752	0.71
911_K	918_K	0.752	0.71
989_G	993_E	0.750	0.71
987_N	1098_A	0.750	0.71
906_Y	909_E	0.749	0.71
486_A	685_R	0.749	0.71
784_M	788_E	0.749	0.71
951_L	955_G	0.749	0.71
1114_C	1131_F	0.748	0.71
677_R	681_D	0.748	0.71
715_A	725_R	0.748	0.71
466_K	711_E	0.747	0.71
655_N	658_G	0.747	0.71
797_Q	801_Q	0.746	0.71
904_D	911_K	0.744	0.70
943_Q	948_E	0.743	0.70
50_E	58_G	0.743	0.70
904_D	915_R	0.743	0.70
356_L	360_V	0.742	0.70
1068_L	1149_H	0.741	0.70
1122_A	1134_Y	0.738	0.70
465_K	706_S	0.738	0.70
14_F	46_W	0.738	0.70
296_E	300_L	0.738	0.70
815_L	919_Q	0.734	0.69
403_D	412_T	0.733	0.69
820_A	831_D	0.732	0.69
1078_P	1128_V	0.732	0.69
468_Q	472_N	0.731	0.69
358_A	361_K	0.731	0.69
792_D	796_K	0.731	0.69
407_S	411_V	0.730	0.69
509_E	569_F	0.729	0.69
301_E	308_K	0.728	0.69
707_I	715_A	0.728	0.69
743_K	750_E	0.728	0.69
890_A	897_I	0.727	0.69
448_I	452_V	0.727	0.69
900_Q	907_E	0.727	0.69
1102_L	1119_V	0.727	0.69
695_L	698_Q	0.727	0.69
692_K	696_L	0.727	0.69
876_K	880_N	0.726	0.69
935_E	939_D	0.726	0.69
462_Y	469_Y	0.725	0.68
820_A	829_E	0.724	0.68
502_G	505_Q	0.724	0.68
46_W	50_E	0.723	0.68
420_N	427_R	0.723	0.68
718_R	721_G	0.723	0.68
962_L	965_D	0.722	0.68
336_K	339_L	0.722	0.68
353_V	360_V	0.722	0.68
1148_T	1161_Y	0.721	0.68
237_L	240_K	0.721	0.68
804_T	855_S	0.721	0.68
150_L	1094_R	0.721	0.68
943_Q	949_Y	0.720	0.68
753_D	756_K	0.720	0.68
497_Q	676_S	0.719	0.68
460_T	464_Q	0.719	0.68
683_T	686_L	0.719	0.68
351_A	354_K	0.718	0.68
104_V	107_S	0.717	0.68
50_E	56_L	0.715	0.67
238_H	241_W	0.715	0.67
61_M	66_F	0.714	0.67
396_R	403_D	0.714	0.67
743_K	758_A	0.713	0.67
386_F	393_A	0.712	0.67
916_L	920_K	0.711	0.67
131_S	138_F	0.711	0.67
936_V	945_L	0.710	0.67
295_E	306_V	0.709	0.67
910_L	913_M	0.709	0.67
384_D	391_S	0.708	0.67
930_K	937_E	0.708	0.67
123_D	1010_D	0.708	0.67
761_E	772_K	0.708	0.67
123_D	126_D	0.707	0.67
398_E	405_Q	0.707	0.67
776_E	780_V	0.707	0.67
391_S	395_I	0.707	0.67
133_L	137_A	0.707	0.67
767_K	774_E	0.706	0.66
704_K	711_E	0.706	0.66
824_Q	831_D	0.706	0.66
296_E	339_L	0.705	0.66
370_H	374_V	0.705	0.66
50_E	134_G	0.705	0.66
402_L	766_R	0.705	0.66
679_L	697_E	0.705	0.66
3_L	56_L	0.705	0.66
539_E	546_A	0.704	0.66
817_I	820_A	0.704	0.66
406_M	410_A	0.704	0.66
903_L	911_K	0.703	0.66
777_L	780_V	0.703	0.66
42_D	150_L	0.701	0.66
35_S	1122_A	0.701	0.66
1168_S	1176_V	0.701	0.66
1149_H	1154_M	0.700	0.66
728_Q	738_L	0.700	0.66
409_S	412_T	0.699	0.66
745_I	759_L	0.699	0.66
150_L	1029_M	0.698	0.66
1063_D	1066_D	0.697	0.65
174_K	1026_D	0.697	0.65
31_G	38_S	0.697	0.65
14_F	1018_L	0.696	0.65
853_D	857_L	0.695	0.65
463_E	466_K	0.693	0.65
854_L	858_T	0.693	0.65
847_L	851_K	0.692	0.65
671_S	674_G	0.691	0.65
1118_E	1124_D	0.691	0.65
192_E	196_H	0.690	0.65
860_E	867_G	0.689	0.65
727_K	731_V	0.689	0.65
385_Y	394_S	0.688	0.64
941_L	945_L	0.687	0.64
469_Y	707_I	0.686	0.64
918_K	921_T	0.686	0.64
1042_S	1046_Q	0.686	0.64
598_S	601_G	0.685	0.64
345_V	782_E	0.685	0.64
658_G	663_G	0.684	0.64
281_E	285_E	0.684	0.64
696_L	700_V	0.684	0.64
402_L	406_M	0.684	0.64
773_L	776_E	0.683	0.64
445_E	452_V	0.683	0.64
39_N	46_W	0.683	0.64
144_G	1071_G	0.683	0.64
7_D	81_T	0.682	0.64
342_Q	349_L	0.682	0.64
344_A	347_E	0.681	0.64
243_T	246_E	0.680	0.64
756_K	759_L	0.680	0.64
263_S	267_A	0.678	0.63
1029_M	1106_L	0.678	0.63
831_D	834_A	0.678	0.63
476_L	483_V	0.678	0.63
801_Q	831_D	0.677	0.63
1027_E	1031_K	0.677	0.63
770_K	780_V	0.677	0.63
289_V	336_K	0.677	0.63
445_E	732_K	0.676	0.63
741_A	748_H	0.675	0.63
793_R	796_K	0.673	0.63
783_K	815_L	0.673	0.63
913_M	929_V	0.673	0.63
718_R	726_L	0.673	0.63
254_E	916_L	0.673	0.63
496_M	499_D	0.673	0.63
602_V	625_L	0.672	0.63
162_E	1057_A	0.672	0.63
868_E	874_A	0.672	0.63
719_E	722_E	0.671	0.63
873_E	876_K	0.671	0.63
472_N	699_E	0.670	0.62
427_R	431_S	0.670	0.62
12_K	32_P	0.669	0.62
554_E	573_T	0.669	0.62
946_R	952_S	0.668	0.62
687_A	691_E	0.668	0.62
260_S	267_A	0.667	0.62
885_T	892_R	0.667	0.62
324_A	331_K	0.666	0.62
354_K	358_A	0.665	0.62
208_Q	1098_A	0.664	0.62
259_S	263_S	0.664	0.62
380_Q	383_S	0.664	0.62
329_Q	332_E	0.663	0.62
829_E	843_T	0.663	0.62
1089_L	1110_P	0.663	0.62
261_A	265_K	0.663	0.62
761_E	764_E	0.663	0.62
343_E	837_K	0.662	0.61
1122_A	1150_R	0.662	0.61
399_L	406_M	0.662	0.61
948_E	953_F	0.662	0.61
918_K	922_T	0.661	0.61
576_P	622_G	0.661	0.61
801_Q	804_T	0.661	0.61
798_K	805_K	0.660	0.61
805_K	808_L	0.660	0.61
632_G	635_E	0.660	0.61
599_F	627_T	0.659	0.61
812_L	820_A	0.659	0.61
935_E	938_L	0.659	0.61
868_E	872_E	0.659	0.61
622_G	663_G	0.658	0.61
46_W	49_G	0.658	0.61
693_T	697_E	0.658	0.61
53_A	61_M	0.658	0.61
212_A	991_I	0.657	0.61
904_D	918_K	0.657	0.61
489_K	685_R	0.657	0.61
928_E	931_L	0.655	0.61
1036_T	1108_V	0.654	0.61
561_I	662_G	0.653	0.60
810_N	817_I	0.653	0.60
809_S	820_A	0.653	0.60
199_E	1005_S	0.652	0.60
475_A	694_A	0.651	0.60
714_L	737_E	0.651	0.60
954_E	957_K	0.651	0.60
52_S	61_M	0.650	0.60
933_R	940_N	0.650	0.60
801_Q	835_R	0.649	0.60
40_I	1163_V	0.649	0.60
491_D	501_S	0.649	0.60
511_L	514_K	0.649	0.60
487_R	491_D	0.648	0.60
925_K	932_G	0.648	0.60
680_E	683_T	0.646	0.60
397_N	401_L	0.645	0.59
335_L	338_E	0.644	0.59
504_Y	509_E	0.644	0.59
637_A	646_I	0.643	0.59
424_L	753_D	0.643	0.59
21_D	1099_I	0.642	0.59
33_N	38_S	0.642	0.59
929_V	943_Q	0.642	0.59
755_E	762_S	0.641	0.59
816_K	831_D	0.641	0.59
351_A	355_Q	0.640	0.59
30_V	50_E	0.640	0.59
498_G	501_S	0.639	0.59
45_R	50_E	0.638	0.59
11_F	39_N	0.638	0.59
541_A	621_L	0.637	0.59
491_D	494_E	0.637	0.59
175_K	179_N	0.636	0.58
875_A	917_Y	0.635	0.58
689_M	692_K	0.634	0.58
386_F	397_N	0.634	0.58
882_K	885_T	0.634	0.58
216_L	988_L	0.634	0.58
523_A	526_E	0.634	0.58
857_L	864_S	0.633	0.58
426_E	748_H	0.632	0.58
410_A	413_L	0.632	0.58
903_L	922_T	0.632	0.58
1052_F	1165_M	0.632	0.58
415_R	422_K	0.632	0.58
537_A	647_V	0.632	0.58
26_V	46_W	0.632	0.58
359_Q	363_K	0.631	0.58
685_R	693_T	0.631	0.58
828_G	839_E	0.630	0.58
508_K	512_K	0.630	0.58
912_E	918_K	0.630	0.58
703_L	710_M	0.630	0.58
1103_F	1135_L	0.630	0.58
648_T	652_D	0.629	0.58
929_V	932_G	0.629	0.58
1125_E	1154_M	0.629	0.58
39_N	49_G	0.628	0.57
1029_M	1150_R	0.628	0.57
293_T	306_V	0.628	0.57
811_E	818_A	0.628	0.57
78_A	104_V	0.628	0.57
249_Q	757_S	0.628	0.57
947_E	952_S	0.627	0.57
228_A	969_A	0.627	0.57
1078_P	1093_E	0.627	0.57
341_K	347_E	0.626	0.57
1153_T	1156_E	0.626	0.57
1048_F	1052_F	0.625	0.57
216_L	220_K	0.625	0.57
941_L	944_Y	0.625	0.57
698_Q	747_T	0.625	0.57
922_T	929_V	0.625	0.57
671_S	677_R	0.625	0.57
441_F	728_Q	0.624	0.57
890_A	894_D	0.624	0.57
442_A	446_Q	0.623	0.57
1109_R	1115_V	0.623	0.57
28_A	1155_E	0.623	0.57
911_K	925_K	0.623	0.57
775_E	778_S	0.622	0.57
1132_A	1150_R	0.621	0.57
853_D	860_E	0.621	0.57
926_D	929_V	0.620	0.56
199_E	1001_Y	0.620	0.56
626_I	649_L	0.620	0.56
891_L	905_T	0.620	0.56
288_Q	291_L	0.619	0.56
342_Q	346_F	0.619	0.56
336_K	844_E	0.618	0.56
325_I	328_F	0.618	0.56
255_E	917_Y	0.618	0.56
906_Y	913_M	0.618	0.56
759_L	763_D	0.618	0.56
785_K	789_E	0.618	0.56
496_M	501_S	0.617	0.56
46_W	1029_M	0.617	0.56
534_Y	606_L	0.617	0.56
215_Y	757_S	0.617	0.56
1120_E	1134_Y	0.617	0.56
256_L	259_S	0.616	0.56
824_Q	835_R	0.616	0.56
922_T	925_K	0.616	0.56
381_L	388_L	0.616	0.56
105_Y	111_E	0.616	0.56
1029_M	1122_A	0.615	0.56
20_V	215_Y	0.614	0.56
743_K	870_K	0.613	0.56
1093_E	1127_N	0.613	0.56
519_G	552_D	0.613	0.56
681_D	684_K	0.612	0.56
1041_R	1138_Y	0.612	0.56
437_C	466_K	0.612	0.56
734_Q	741_A	0.611	0.55
705_H	708_Q	0.610	0.55
465_K	707_I	0.610	0.55
152_S	1082_K	0.610	0.55
505_Q	510_V	0.610	0.55
93_I	98_V	0.610	0.55
733_G	736_Y	0.609	0.55
774_E	780_V	0.609	0.55
504_Y	510_V	0.609	0.55
344_A	349_L	0.609	0.55
439_T	454_A	0.609	0.55
1021_V	1029_M	0.608	0.55
413_L	420_N	0.608	0.55
802_S	823_E	0.608	0.55
598_S	632_G	0.607	0.55
697_E	701_K	0.606	0.55
530_T	541_A	0.606	0.55
748_H	752_Y	0.605	0.55
86_N	1014_A	0.605	0.55
448_I	724_L	0.604	0.55
866_S	870_K	0.604	0.55
67_A	1085_N	0.604	0.55
1030_T	1066_D	0.604	0.55
234_I	238_H	0.603	0.54
46_W	61_M	0.603	0.54
128_F	139_S	0.603	0.54
686_L	689_M	0.602	0.54
1078_P	1103_F	0.602	0.54
725_R	728_Q	0.602	0.54
505_Q	513_A	0.601	0.54
271_D	347_E	0.601	0.54
711_E	714_L	0.601	0.54
813_T	828_G	0.601	0.54
454_A	720_T	0.600	0.54
456_R	459_Q	0.600	0.54
923_L	930_K	0.600	0.54
49_G	52_S	0.599	0.54
672_L	681_D	0.599	0.54
40_I	1147_I	0.599	0.54
141_I	153_K	0.598	0.54
143_Q	1071_G	0.598	0.54
1132_A	1156_E	0.598	0.54
1134_Y	1150_R	0.597	0.54
1033_F	1052_F	0.596	0.54
920_K	923_L	0.596	0.54
389_L	396_R	0.596	0.54
287_Q	290_L	0.596	0.54
406_M	409_S	0.596	0.54
721_G	726_L	0.595	0.53
419_N	422_K	0.595	0.53
910_L	922_T	0.595	0.53
12_K	57_R	0.595	0.53
550_V	662_G	0.594	0.53
911_K	922_T	0.594	0.53
921_T	933_R	0.594	0.53
827_K	832_N	0.594	0.53
504_Y	508_K	0.593	0.53
261_A	292_V	0.593	0.53
580_I	616_V	0.593	0.53
809_S	822_K	0.593	0.53
231_A	234_I	0.592	0.53
449_H	453_G	0.592	0.53
1055_G	1071_G	0.592	0.53
46_W	139_S	0.592	0.53
864_S	868_E	0.592	0.53
604_S	618_Q	0.592	0.53
187_N	1014_A	0.591	0.53
433_R	437_C	0.591	0.53
45_R	174_K	0.590	0.53
158_R	167_V	0.590	0.53
935_E	943_Q	0.589	0.53
261_A	268_K	0.589	0.53
165_A	1036_T	0.589	0.53
29_V	1115_V	0.588	0.53
674_G	680_E	0.588	0.53
570_G	663_G	0.588	0.53
360_V	367_L	0.588	0.53
1077_Q	1083_L	0.587	0.52
1159_V	1175_S	0.587	0.52
540_I	650_E	0.587	0.52
953_F	959_K	0.586	0.52
165_A	174_K	0.586	0.52
194_I	1107_K	0.586	0.52
938_L	942_L	0.586	0.52
422_K	425_Q	0.585	0.52
799_Q	803_S	0.585	0.52
522_G	658_G	0.584	0.52
925_K	937_E	0.584	0.52
489_K	500_F	0.584	0.52
922_T	934_M	0.583	0.52
25_G	157_R	0.583	0.52
756_K	760_S	0.583	0.52
840_L	847_L	0.583	0.52
473_E	476_L	0.582	0.52
734_Q	739_Q	0.582	0.52
713_K	738_L	0.582	0.52
674_G	749_L	0.582	0.52
378_I	382_K	0.582	0.52
363_K	811_E	0.582	0.52
740_V	744_N	0.582	0.52
461_K	837_K	0.582	0.52
429_D	432_A	0.581	0.52
909_E	918_K	0.581	0.52
253_E	852_E	0.581	0.52
249_Q	253_E	0.581	0.52
1080_G	1165_M	0.580	0.52
393_A	397_N	0.580	0.52
254_E	258_E	0.580	0.52
723_G	734_Q	0.580	0.52
813_T	819_A	0.580	0.52
433_R	440_E	0.579	0.51
549_V	572_A	0.579	0.51
875_A	909_E	0.579	0.51
49_G	57_R	0.578	0.51
252_K	928_E	0.577	0.51
1130_R	1164_T	0.577	0.51
177_A	1021_V	0.577	0.51
1110_P	1120_E	0.577	0.51
173_R	180_K	0.577	0.51
800_T	803_S	0.576	0.51
1085_N	1125_E	0.575	0.51
902_G	919_Q	0.575	0.51
32_P	42_D	0.575	0.51
312_K	315_V	0.574	0.51
600_L	635_E	0.574	0.51
34_G	38_S	0.574	0.51
138_F	1114_C	0.574	0.51
62_E	1051_L	0.574	0.51
674_G	697_E	0.574	0.51
624_V	645_R	0.572	0.51
816_K	826_C	0.571	0.50
14_F	50_E	0.571	0.50
187_N	190_R	0.571	0.50
1064_P	1067_L	0.570	0.50
915_R	920_K	0.570	0.50
91_L	94_D	0.570	0.50
924_L	927_E	0.570	0.50
802_S	813_T	0.570	0.50
411_V	414_Q	0.569	0.50
604_S	609_F	0.569	0.50
956_A	959_K	0.569	0.50
1078_P	1127_N	0.569	0.50
942_L	949_Y	0.568	0.50
508_K	513_A	0.568	0.50
9_I	17_R	0.568	0.50
804_T	849_E	0.567	0.50
818_A	892_R	0.567	0.50
788_E	795_T	0.567	0.50
936_V	940_N	0.567	0.50
903_L	907_E	0.567	0.50
1081_K	1127_N	0.567	0.50
46_W	51_Q	0.567	0.50
374_V	377_K	0.567	0.50
726_L	729_Q	0.567	0.50
11_F	14_F	0.566	0.50
338_E	342_Q	0.566	0.50
427_R	742_E	0.566	0.50
884_K	899_L	0.565	0.50
737_E	741_A	0.565	0.50
961_Q	964_T	0.565	0.50
685_R	689_M	0.564	0.50
411_V	430_I	0.564	0.50
126_D	129_M	0.564	0.50
955_G	959_K	0.564	0.50
176_K	180_K	0.563	0.50
351_A	446_Q	0.563	0.50
1125_E	1152_G	0.563	0.50
173_R	1022_I	0.563	0.50
318_Q	854_L	0.562	0.49
469_Y	473_E	0.562	0.49
390_N	400_Q	0.562	0.49
766_R	780_V	0.561	0.49
831_D	835_R	0.561	0.49
48_L	1148_T	0.561	0.49
752_Y	763_D	0.561	0.49
539_E	671_S	0.560	0.49
461_K	468_Q	0.560	0.49
1175_S	1178_L	0.559	0.49
487_R	494_E	0.558	0.49
393_A	403_D	0.558	0.49
362_E	851_K	0.558	0.49
1025_M	1029_M	0.558	0.49
1117_D	1124_D	0.558	0.49
814_E	818_A	0.558	0.49
623_T	643_R	0.558	0.49
479_A	689_M	0.557	0.49
744_N	747_T	0.557	0.49
946_R	950_S	0.557	0.49
718_R	744_N	0.557	0.49
858_T	861_M	0.557	0.49
794_L	798_K	0.556	0.49
1044_F	1048_F	0.555	0.49
401_L	404_D	0.555	0.49
309_E	353_V	0.555	0.49
242_S	340_S	0.555	0.49
539_E	675_R	0.555	0.49
486_A	489_K	0.555	0.49
914_K	917_Y	0.555	0.49
892_R	922_T	0.554	0.48
911_K	937_E	0.554	0.48
1133_Q	1136_K	0.554	0.48
771_R	782_E	0.554	0.48
910_L	932_G	0.554	0.48
201_Q	997_V	0.554	0.48
458_M	462_Y	0.553	0.48
912_E	915_R	0.553	0.48
619_N	659_S	0.553	0.48
1063_D	1067_L	0.553	0.48
910_L	921_T	0.553	0.48
301_E	309_E	0.553	0.48
144_G	1098_A	0.553	0.48
3_L	6_L	0.553	0.48
1149_H	1165_M	0.552	0.48
43_A	56_L	0.552	0.48
1128_V	1132_A	0.552	0.48
745_I	751_L	0.552	0.48
903_L	926_D	0.552	0.48
879_L	882_K	0.551	0.48
45_R	1114_C	0.551	0.48
829_E	840_L	0.551	0.48
763_D	773_L	0.550	0.48
897_I	901_H	0.550	0.48
129_M	141_I	0.550	0.48
805_K	813_T	0.550	0.48
90_F	93_I	0.550	0.48
976_I	980_I	0.550	0.48
980_I	986_V	0.549	0.48
72_R	1170_V	0.549	0.48
863_S	866_S	0.549	0.48
1075_I	1097_T	0.549	0.48
780_V	787_L	0.549	0.48
926_D	931_L	0.549	0.48
722_E	730_D	0.549	0.48
1006_E	1009_E	0.549	0.48
1094_R	1103_F	0.549	0.48
378_I	385_Y	0.549	0.48
780_V	784_M	0.549	0.48
11_F	38_S	0.548	0.48
1053_G	1114_C	0.548	0.48
1106_L	1152_G	0.548	0.48
6_L	488_S	0.548	0.48
46_W	1149_H	0.547	0.48
896_R	903_L	0.547	0.48
69_S	1168_S	0.547	0.48
1054_G	1079_P	0.547	0.48
254_E	923_L	0.546	0.47
842_E	849_E	0.546	0.47
114_I	292_V	0.546	0.47
808_L	816_K	0.545	0.47
229_L	973_V	0.545	0.47
41_T	44_I	0.545	0.47
752_Y	769_R	0.543	0.47
915_R	921_T	0.543	0.47
2_F	84_L	0.543	0.47
887_E	890_A	0.543	0.47
210_S	975_L	0.542	0.47
315_V	318_Q	0.542	0.47
58_G	1088_L	0.542	0.47
45_R	128_F	0.542	0.47
805_K	826_C	0.542	0.47
939_D	942_L	0.542	0.47
294_S	299_K	0.541	0.47
489_K	495_T	0.541	0.47
282_S	285_E	0.541	0.47
794_L	830_E	0.540	0.47
126_D	170_Y	0.540	0.47
506_G	513_A	0.540	0.47
1116_L	1135_L	0.540	0.47
522_G	550_V	0.540	0.47
759_L	762_S	0.539	0.47
248_V	252_K	0.539	0.47
14_F	139_S	0.538	0.46
66_F	1052_F	0.538	0.46
204_P	1120_E	0.538	0.46
467_R	471_K	0.538	0.46
910_L	915_R	0.537	0.46
1103_F	1127_N	0.536	0.46
905_T	908_R	0.535	0.46
316_Q	319_E	0.535	0.46
7_D	83_T	0.535	0.46
46_W	1052_F	0.535	0.46
299_K	306_V	0.535	0.46
403_D	774_E	0.535	0.46
1031_K	1034_N	0.534	0.46
105_Y	113_L	0.534	0.46
828_G	846_A	0.534	0.46
262_I	917_Y	0.534	0.46
596_H	599_F	0.533	0.46
765_E	778_S	0.533	0.46
582_D	615_S	0.532	0.46
843_T	854_L	0.532	0.46
129_M	138_F	0.531	0.46
168_L	171_K	0.531	0.46
486_A	686_L	0.531	0.46
802_S	827_K	0.530	0.45
33_N	39_N	0.530	0.45
942_L	945_L	0.530	0.45
906_Y	920_K	0.529	0.45
473_E	495_T	0.529	0.45
407_S	415_R	0.529	0.45
1009_E	1012_T	0.528	0.45
387_E	390_N	0.528	0.45
633_A	654_V	0.528	0.45
86_N	98_V	0.528	0.45
431_S	434_K	0.528	0.45
1106_L	1150_R	0.528	0.45
999_E	1003_F	0.528	0.45
86_N	1095_A	0.527	0.45
1128_V	1144_F	0.527	0.45
834_A	855_S	0.527	0.45
696_L	727_K	0.527	0.45
555_Q	559_K	0.527	0.45
570_G	574_F	0.527	0.45
815_L	826_C	0.526	0.45
50_E	620_L	0.526	0.45
740_V	743_K	0.526	0.45
6_L	1110_P	0.526	0.45
465_K	469_Y	0.526	0.45
134_G	1052_F	0.526	0.45
353_V	364_Q	0.525	0.45
56_L	108_G	0.525	0.45
221_E	976_I	0.525	0.45
59_G	84_L	0.525	0.45
106_R	109_E	0.525	0.45
35_S	1114_C	0.524	0.45
1125_E	1131_F	0.524	0.45
32_P	1162_G	0.524	0.45
865_T	872_E	0.523	0.45
921_T	924_L	0.523	0.45
100_V	127_L	0.523	0.45
504_Y	507_V	0.523	0.45
868_E	878_K	0.523	0.45
756_K	847_L	0.521	0.44
933_R	939_D	0.521	0.44
14_F	158_R	0.521	0.44
745_I	749_L	0.520	0.44
613_Y	617_I	0.519	0.44
749_L	756_K	0.519	0.44
29_V	277_Q	0.519	0.44
944_Y	953_F	0.519	0.44
76_N	106_R	0.519	0.44
396_R	399_L	0.518	0.44
1038_V	1042_S	0.518	0.44
81_T	116_N	0.518	0.44
394_S	445_E	0.518	0.44
41_T	48_L	0.518	0.44
29_V	198_L	0.517	0.44
559_K	566_Q	0.517	0.44
813_T	827_K	0.517	0.44
1048_F	1078_P	0.516	0.44
711_E	715_A	0.516	0.44
759_L	774_E	0.516	0.44
483_V	487_R	0.516	0.44
749_L	763_D	0.516	0.44
871_L	875_A	0.516	0.44
66_F	1169_G	0.515	0.44
328_F	335_L	0.515	0.44
393_A	422_K	0.515	0.44
28_A	42_D	0.515	0.44
799_Q	823_E	0.515	0.44
439_T	442_A	0.515	0.44
927_E	930_K	0.514	0.44
904_D	922_T	0.514	0.44
540_I	647_V	0.514	0.44
811_E	815_L	0.513	0.43
427_R	745_I	0.513	0.43
158_R	177_A	0.513	0.43
148_E	151_S	0.513	0.43
918_K	934_M	0.513	0.43
1125_E	1165_M	0.512	0.43
215_Y	219_K	0.512	0.43
658_G	661_T	0.512	0.43
61_M	1148_T	0.512	0.43
891_L	894_D	0.512	0.43
436_A	439_T	0.512	0.43
505_Q	514_K	0.512	0.43
169_K	180_K	0.512	0.43
558_R	631_K	0.511	0.43
1083_L	1130_R	0.510	0.43
396_R	400_Q	0.510	0.43
346_F	350_Q	0.510	0.43
769_R	778_S	0.510	0.43
1052_F	1161_Y	0.509	0.43
61_M	1078_P	0.509	0.43
672_L	675_R	0.509	0.43
1142_T	1154_M	0.509	0.43
13_S	1099_I	0.509	0.43
720_T	749_L	0.509	0.43
425_Q	429_D	0.509	0.43
1039_Q	1042_S	0.508	0.43
676_S	683_T	0.506	0.43
133_L	1036_T	0.506	0.43
488_S	491_D	0.505	0.42
27_T	1128_V	0.505	0.42
266_E	270_E	0.505	0.42
179_N	183_E	0.505	0.42
495_T	498_G	0.504	0.42
1033_F	1061_L	0.504	0.42
137_A	142_S	0.504	0.42
12_K	42_D	0.504	0.42
773_L	780_V	0.504	0.42
10_G	1148_T	0.504	0.42
330_Q	333_T	0.503	0.42
144_G	166_G	0.503	0.42
81_T	121_L	0.503	0.42
48_L	1043_H	0.503	0.42
814_E	834_A	0.503	0.42
683_T	687_A	0.503	0.42
834_A	856_F	0.503	0.42
721_G	724_L	0.503	0.42
1040_I	1119_V	0.502	0.42
902_G	915_R	0.502	0.42
141_I	1119_V	0.502	0.42
823_E	827_K	0.502	0.42
774_E	783_K	0.502	0.42
607_V	939_D	0.502	0.42
260_S	263_S	0.502	0.42
10_G	45_R	0.500	0.42
1107_K	1141_D	0.500	0.42
142_S	1029_M	0.500	0.42
804_T	808_L	0.500	0.42

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ux3A	1	0.3642	100	0.698	Contact Map
3zgxA	2	0.296	100	0.712	Contact Map
1w1wA	2	0.2723	100	0.748	Contact Map
4ad8A	1	0.3533	100	0.776	Contact Map
4i99A	2	0.274	100	0.794	Contact Map
4rsiB	1	0.3221	100	0.81	Contact Map
3auyA	2	0.3002	100	0.815	Contact Map
4rsiA	1	0.2352	100	0.82	Contact Map
3ktaB	1	0.1341	100	0.831	Contact Map
4abyA	1	0.2858	100	0.848	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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