GREMLIN Database
ILVD - Dihydroxy-acid dehydratase
UniProt: P51785 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 558 (545)
Sequences: 4718 (1888)
Seq/√Len: 80.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
405_E504_I4.4871.00
496_F525_K4.3911.00
253_V258_I3.9161.00
256_K339_H3.7441.00
387_P493_P3.6261.00
405_E515_Q3.5761.00
496_F521_W3.4651.00
504_I515_Q3.4611.00
259_D339_H3.3271.00
405_E502_H3.2661.00
428_E463_K3.2551.00
506_D509_K3.1711.00
498_E527_N3.1451.00
248_K251_D3.1361.00
115_G243_I3.0551.00
497_V514_V2.8931.00
332_S340_L2.8241.00
340_L351_G2.7921.00
177_N180_E2.7901.00
388_D551_N2.7551.00
502_H515_Q2.7501.00
137_N250_R2.7411.00
137_N251_D2.6811.00
366_H370_Q2.6651.00
409_V430_D2.6441.00
37_I115_G2.6291.00
170_A175_K2.5821.00
504_I513_D2.5511.00
253_V257_A2.5151.00
134_M253_V2.4681.00
407_P502_H2.4161.00
346_T353_T2.4051.00
409_V499_N2.4001.00
292_E382_F2.3921.00
440_K490_E2.3811.00
143_V235_S2.3641.00
238_Q241_E2.3291.00
498_E520_E2.3191.00
213_L253_V2.3181.00
130_L213_L2.3181.00
517_P520_E2.2951.00
520_E523_K2.2821.00
384_N513_D2.2801.00
141_I239_L2.2521.00
264_L328_L2.2101.00
220_T315_I2.2051.00
263_A300_R2.1991.00
23_R186_Q2.1921.00
256_K341_D2.1891.00
467_I484_V2.1881.00
295_N299_E2.1821.00
413_S416_E2.1811.00
130_L281_L2.1531.00
403_R506_D2.1491.00
262_F294_I2.1441.00
412_D435_R2.1331.00
162_S475_A2.1261.00
263_A301_V2.1131.00
516_V521_W2.1041.00
390_A512_L2.1041.00
266_M297_V2.0951.00
41_N73_E2.0901.00
342_A350_L2.0791.00
348_K352_E2.0611.00
23_R29_E2.0391.00
518_E522_E2.0121.00
149_A224_T1.9901.00
528_W531_F1.9821.00
255_V259_D1.9641.00
402_T508_E1.9521.00
523_K526_A1.9311.00
37_I243_I1.9191.00
290_S293_R1.9141.00
234_K237_A1.9061.00
385_L497_V1.8841.00
295_N510_R1.8791.00
171_Y176_I1.8671.00
514_V521_W1.8501.00
69_G240_M1.8421.00
118_C140_T1.8301.00
141_I238_Q1.8051.00
208_S214_A1.8041.00
497_V503_I1.8031.00
241_E244_R1.8011.00
227_E319_H1.7941.00
171_Y178_E1.7891.00
349_T352_E1.7821.00
523_K527_N1.7791.00
259_D296_E1.7571.00
328_L350_L1.7421.00
412_D416_E1.7331.00
379_A510_R1.7261.00
497_V516_V1.7111.00
134_M285_A1.6991.00
521_W525_K1.6931.00
66_E237_A1.6791.00
133_A140_T1.6761.00
522_E526_A1.6721.00
532_E536_K1.6581.00
328_L354_I1.6511.00
541_A545_K1.6511.00
241_E245_K1.6341.00
115_G239_L1.6321.00
403_R508_E1.6271.00
214_A218_N1.6201.00
404_H407_P1.6101.00
108_V116_M1.6081.00
263_A297_V1.5981.00
176_I180_E1.5951.00
64_I69_G1.5941.00
238_Q245_K1.5891.00
262_F289_Y1.5891.00
419_D423_N1.5721.00
150_A316_E1.5681.00
141_I345_V1.5641.00
203_S270_G1.5621.00
55_E229_K1.5450.99
210_A264_L1.5440.99
412_D436_Y1.5380.99
65_R71_P1.5280.99
493_P521_W1.5260.99
403_R504_I1.5180.99
39_V64_I1.4730.99
407_P430_D1.4720.99
410_V497_V1.4670.99
47_V78_G1.4650.99
293_R296_E1.4630.99
411_F420_G1.4610.99
420_G426_V1.4600.99
296_E300_R1.4580.99
299_E375_K1.4560.99
59_I233_R1.4550.99
218_N231_F1.4530.99
260_N342_A1.4490.99
131_M284_E1.4470.99
255_V293_R1.4460.99
485_S551_N1.4380.99
411_F425_K1.4320.99
424_R458_M1.4260.99
58_K62_E1.4180.99
29_E182_Q1.4120.99
408_A503_I1.4090.99
31_D34_K1.3940.99
57_G119_I1.3930.99
60_V117_V1.3870.99
516_V520_E1.3830.99
153_T180_E1.3790.99
354_I357_H1.3740.99
283_N552_T1.3690.99
522_E525_K1.3640.99
40_C107_V1.3590.99
313_V363_D1.3500.99
513_D518_E1.3440.99
256_K259_D1.3420.99
62_E65_R1.3380.99
27_V72_F1.3380.99
242_T247_I1.3320.98
330_E334_K1.3230.98
348_K353_T1.3120.98
275_V279_L1.3090.98
318_L327_A1.3040.98
203_S274_T1.3030.98
306_K312_D1.3010.98
416_E419_D1.2970.98
79_V110_A1.2800.98
64_I236_A1.2800.98
45_D61_K1.2790.98
53_L121_N1.2790.98
408_A497_V1.2620.98
213_L249_P1.2620.98
37_I64_I1.2620.98
278_T289_Y1.2530.98
330_E362_Y1.2450.98
63_A236_A1.2400.98
252_I257_A1.2380.98
59_I229_K1.2380.98
36_F72_F1.2360.98
130_L208_S1.2290.97
160_S314_F1.2280.97
255_V296_E1.2250.97
292_E296_E1.2150.97
210_A328_L1.2140.97
38_A108_V1.2120.97
183_E187_F1.2120.97
253_V285_A1.2110.97
432_V455_I1.2100.97
258_I281_L1.2080.97
46_I113_F1.2080.97
496_F516_V1.2080.97
117_V239_L1.2060.97
495_A528_W1.2050.97
54_Q58_K1.2000.97
137_N248_K1.2000.97
362_Y370_Q1.1930.97
359_V362_Y1.1930.97
403_R509_K1.1870.97
332_S338_L1.1840.97
433_I503_I1.1810.97
38_A116_M1.1780.97
384_N518_E1.1740.97
117_V236_A1.1730.97
533_P536_K1.1710.97
496_F528_W1.1660.96
159_I184_L1.1650.96
485_S549_S1.1630.96
335_E368_L1.1600.96
132_A136_I1.1590.96
410_V499_N1.1570.96
388_D485_S1.1560.96
338_L350_L1.1490.96
521_W524_R1.1480.96
433_I497_V1.1440.96
16_A164_V1.1430.96
303_H373_T1.1410.96
288_E552_T1.1390.96
77_I103_S1.1370.96
415_D446_P1.1360.96
398_Q462_P1.1340.96
40_C116_M1.1340.96
27_V70_V1.1330.96
349_T353_T1.1310.96
548_T552_T1.1290.96
415_D419_D1.1280.96
456_V461_G1.1270.96
392_I505_V1.1240.96
134_M213_L1.1180.96
66_E233_R1.1170.95
409_V427_K1.1160.95
59_I62_E1.1080.95
144_S218_N1.1060.95
118_C142_F1.1050.95
409_V420_G1.1050.95
43_Y54_Q1.1020.95
246_D249_P1.1010.95
154_S180_E1.0960.95
19_R185_E1.0900.95
494_L497_V1.0860.95
104_V132_A1.0800.95
430_D499_N1.0780.95
380_V391_I1.0770.94
367_P370_Q1.0760.94
332_S351_G1.0710.94
465_A505_V1.0640.94
63_A66_E1.0640.94
255_V288_E1.0610.94
220_T319_H1.0610.94
221_I225_S1.0580.94
549_S552_T1.0570.94
29_E186_Q1.0540.94
132_A249_P1.0500.94
259_D293_R1.0430.93
91_R446_P1.0430.93
182_Q186_Q1.0420.93
120_P126_T1.0410.93
388_D552_T1.0400.93
493_P514_V1.0360.93
329_N357_H1.0350.93
154_S183_E1.0350.93
409_V426_V1.0200.93
55_E58_K1.0160.93
412_D498_E1.0160.93
352_E355_A1.0130.92
22_L25_A1.0110.92
407_P427_K1.0110.92
24_A48_P1.0090.92
251_D343_L1.0090.92
32_F70_V1.0060.92
452_T472_F1.0000.92
379_A508_E0.9990.92
384_N514_V0.9980.92
216_P353_T0.9970.92
427_K430_D0.9950.92
329_N356_G0.9900.92
350_L353_T0.9890.92
118_C133_A0.9880.92
516_V525_K0.9870.91
428_E462_P0.9860.91
149_A225_S0.9850.91
437_E446_P0.9820.91
42_S129_M0.9780.91
238_Q242_T0.9770.91
428_E458_M0.9770.91
211_L258_I0.9750.91
17_P168_V0.9750.91
62_E233_R0.9740.91
456_V480_S0.9700.91
332_S354_I0.9680.91
388_D549_S0.9680.91
525_K528_W0.9630.90
87_H111_H0.9560.90
385_L493_P0.9550.90
539_Y556_M0.9530.90
426_V432_V0.9520.90
221_I231_F0.9470.90
149_A191_T0.9450.90
265_D274_T0.9440.90
335_E369_D0.9430.90
276_L279_L0.9390.89
191_T226_P0.9380.89
543_Y547_V0.9360.89
533_P541_A0.9350.89
316_E320_E0.9310.89
226_P230_E0.9300.89
534_K538_G0.9300.89
493_P525_K0.9270.89
268_L327_A0.9260.89
247_I251_D0.9180.88
92_Y109_S0.9160.88
329_N332_S0.9130.88
141_I235_S0.9120.88
23_R32_F0.9110.88
431_V503_I0.9110.88
405_E513_D0.9100.88
381_L390_A0.9090.88
514_V517_P0.9070.88
211_L261_A0.9070.88
153_T184_L0.9060.88
100_I128_G0.9030.87
13_I171_Y0.9030.87
400_G462_P0.9000.87
215_L238_Q0.9000.87
257_A343_L0.8990.87
102_D542_R0.8980.87
433_I514_V0.8950.87
61_K73_E0.8820.86
62_E66_E0.8820.86
230_E234_K0.8810.86
491_G528_W0.8740.86
481_I505_V0.8720.85
240_M244_R0.8690.85
362_Y367_P0.8690.85
51_V192_C0.8680.85
332_S355_A0.8680.85
34_K70_V0.8670.85
255_V287_V0.8660.85
409_V425_K0.8640.85
99_I106_T0.8630.85
99_I539_Y0.8630.85
306_K313_V0.8600.85
401_I404_H0.8600.85
252_I343_L0.8590.85
36_F70_V0.8570.84
330_E369_D0.8540.84
40_C104_V0.8520.84
53_L145_G0.8520.84
214_A235_S0.8470.84
57_G73_E0.8440.84
52_H145_G0.8420.83
299_E510_R0.8410.83
134_M258_I0.8400.83
528_W532_E0.8400.83
145_G194_S0.8380.83
336_G368_L0.8380.83
304_L368_L0.8350.83
392_I507_I0.8350.83
542_R546_L0.8330.83
213_L252_I0.8320.83
434_I437_E0.8320.83
426_V499_N0.8310.83
238_Q247_I0.8310.83
328_L338_L0.8290.82
312_D363_D0.8280.82
321_A362_Y0.8280.82
537_T541_A0.8280.82
404_H431_V0.8270.82
236_A239_L0.8250.82
104_V129_M0.8240.82
69_G236_A0.8220.82
301_V337_A0.8190.82
421_I451_P0.8170.82
504_I511_I0.8150.81
149_A222_L0.8150.81
158_K316_E0.8140.81
519_E523_K0.8130.81
350_L354_I0.8080.81
264_L324_V0.8060.81
79_V106_T0.8060.81
117_V143_V0.8040.81
28_K31_D0.8040.81
227_E230_E0.8030.80
351_G355_A0.8020.80
318_L365_I0.8010.80
120_P142_F0.8010.80
250_R286_G0.7990.80
217_G319_H0.7980.80
379_A394_T0.7950.80
329_N334_K0.7940.80
343_L353_T0.7900.79
467_I497_V0.7900.79
34_K66_E0.7900.79
38_A113_F0.7890.79
207_L265_D0.7830.79
254_T257_A0.7810.79
64_I117_V0.7810.79
306_K366_H0.7790.78
80_D84_A0.7790.78
436_Y495_A0.7780.78
321_A359_V0.7780.78
42_S76_T0.7750.78
78_G125_I0.7750.78
332_S336_G0.7730.78
39_V61_K0.7720.78
88_I535_V0.7720.78
53_L73_E0.7720.78
41_N53_L0.7690.77
242_T345_V0.7680.77
206_C268_L0.7670.77
63_A233_R0.7670.77
340_L354_I0.7640.77
297_V300_R0.7640.77
343_L348_K0.7630.77
412_D531_F0.7620.77
283_N288_E0.7610.77
529_K532_E0.7610.77
106_T539_Y0.7590.77
351_G354_I0.7580.76
240_M243_I0.7580.76
258_I287_V0.7560.76
130_L253_V0.7550.76
433_I484_V0.7540.76
481_I484_V0.7500.76
167_G184_L0.7490.76
295_N379_A0.7470.75
39_V60_V0.7440.75
35_P69_G0.7420.75
79_V93_S0.7420.75
247_I343_L0.7400.75
256_K342_A0.7400.75
516_V524_R0.7390.75
342_A349_T0.7370.74
418_L450_A0.7370.74
300_R337_A0.7350.74
267_A304_L0.7340.74
484_V494_L0.7340.74
263_A337_A0.7310.74
45_D73_E0.7310.74
412_D499_N0.7300.74
134_M257_A0.7300.74
153_T183_E0.7290.74
247_I353_T0.7280.74
275_V294_I0.7270.73
343_L346_T0.7250.73
398_Q401_I0.7250.73
198_M268_L0.7240.73
542_R556_M0.7230.73
531_F534_K0.7230.73
229_K233_R0.7230.73
476_S480_S0.7220.73
15_R18_H0.7220.73
206_C219_G0.7210.73
64_I71_P0.7190.73
161_L165_F0.7180.72
67_A236_A0.7170.72
548_T555_I0.7160.72
232_V235_S0.7150.72
10_T36_F0.7140.72
337_A368_L0.7130.72
406_G431_V0.7130.72
159_I163_S0.7120.72
385_L435_R0.7120.72
116_M140_T0.7120.72
239_L243_I0.7120.72
445_M550_A0.7120.72
426_V430_D0.7100.72
536_K541_A0.7100.72
341_D351_G0.7100.72
49_G80_D0.7100.72
178_E182_Q0.7100.72
262_F278_T0.7100.72
170_A176_I0.7080.71
250_R537_T0.7070.71
42_S120_P0.7050.71
144_S205_N0.7040.71
39_V116_M0.7040.71
518_E521_W0.7010.71
442_G446_P0.6990.70
516_V522_E0.6990.70
336_G340_L0.6970.70
64_I239_L0.6960.70
120_P129_M0.6960.70
385_L513_D0.6950.70
305_A327_A0.6950.70
517_P523_K0.6940.70
489_A530_G0.6900.69
63_A67_A0.6880.69
144_S228_R0.6880.69
283_N555_I0.6870.69
490_E549_S0.6870.69
213_L254_T0.6850.69
339_H342_A0.6830.69
242_T245_K0.6820.69
518_E524_R0.6820.69
85_M197_G0.6810.68
67_A240_M0.6800.68
152_R158_K0.6800.68
207_L278_T0.6800.68
40_C74_F0.6800.68
407_P431_V0.6790.68
53_L57_G0.6780.68
334_K351_G0.6750.68
407_P504_I0.6730.68
425_K430_D0.6730.68
165_F197_G0.6720.67
207_L211_L0.6720.67
137_N249_P0.6720.67
507_I510_R0.6720.67
325_S353_T0.6710.67
28_K32_F0.6700.67
159_I162_S0.6700.67
503_I514_V0.6690.67
495_A531_F0.6690.67
22_L27_V0.6670.67
253_V289_Y0.6670.67
153_T159_I0.6670.67
86_G450_A0.6660.67
286_G537_T0.6650.67
258_I289_Y0.6640.67
275_V391_I0.6640.67
291_L551_N0.6640.67
506_D511_I0.6640.67
31_D237_A0.6630.66
422_I475_A0.6620.66
416_E420_G0.6620.66
60_V119_I0.6610.66
410_V514_V0.6610.66
47_V107_V0.6610.66
148_M189_C0.6600.66
76_T103_S0.6600.66
533_P538_G0.6590.66
517_P521_W0.6580.66
259_D341_D0.6580.66
44_I107_V0.6570.66
348_K356_G0.6570.66
141_I242_T0.6560.66
162_S308_A0.6560.66
313_V364_V0.6530.65
235_S239_L0.6530.65
221_I319_H0.6530.65
489_A547_V0.6530.65
427_K460_L0.6520.65
242_T252_I0.6520.65
382_F388_D0.6520.65
59_I63_A0.6510.65
411_F426_V0.6490.65
20_S164_V0.6470.65
192_C224_T0.6450.64
257_A287_V0.6440.64
160_S163_S0.6440.64
30_E234_K0.6410.64
398_Q402_T0.6410.64
289_Y294_I0.6400.64
431_V465_A0.6400.64
295_N298_A0.6400.64
282_A287_V0.6380.63
252_I344_T0.6380.63
310_A395_G0.6370.63
11_Q33_G0.6370.63
519_E522_E0.6360.63
428_E460_L0.6360.63
250_R285_A0.6340.63
254_T342_A0.6340.63
63_A237_A0.6330.63
375_K402_T0.6320.63
153_T176_I0.6310.63
140_T249_P0.6300.62
138_I249_P0.6290.62
210_A324_V0.6290.62
342_A351_G0.6290.62
538_G541_A0.6280.62
38_A74_F0.6280.62
164_V184_L0.6280.62
44_I78_G0.6260.62
230_E233_R0.6260.62
262_F297_V0.6250.62
257_A285_A0.6250.62
116_M136_I0.6240.62
299_E379_A0.6240.62
520_E524_R0.6220.62
210_A342_A0.6220.62
346_T349_T0.6220.62
425_K499_N0.6210.61
42_S78_G0.6210.61
22_L72_F0.6210.61
170_A180_E0.6210.61
54_Q61_K0.6200.61
160_S475_A0.6200.61
76_T129_M0.6200.61
363_D366_H0.6190.61
508_E511_I0.6180.61
152_R157_R0.6180.61
22_L32_F0.6150.61
208_S281_L0.6150.61
310_A396_G0.6150.61
379_A392_I0.6140.61
163_S475_A0.6140.61
108_V138_I0.6140.61
39_V57_G0.6140.61
385_L514_V0.6130.60
166_E477_R0.6120.60
397_V507_I0.6110.60
54_Q73_E0.6110.60
303_H395_G0.6100.60
157_R180_E0.6090.60
46_I107_V0.6090.60
263_A331_L0.6080.60
50_H148_M0.6080.60
16_A181_L0.6080.60
490_E551_N0.6060.60
225_S319_H0.6040.59
326_A365_I0.6040.59
217_G325_S0.6040.59
307_L318_L0.6040.59
17_P165_F0.6030.59
166_E169_G0.6020.59
152_R320_E0.6020.59
340_L355_A0.6010.59
408_A431_V0.6010.59
295_N375_K0.6000.59
417_A432_V0.6000.59
164_V188_G0.5990.59
99_I103_S0.5980.59
171_Y181_L0.5980.59
233_R237_A0.5970.58
18_H86_G0.5960.58
23_R182_Q0.5960.58
150_A196_S0.5950.58
330_E368_L0.5950.58
37_I239_L0.5950.58
491_G496_F0.5940.58
121_N145_G0.5940.58
304_L366_H0.5930.58
88_I109_S0.5930.58
208_S213_L0.5930.58
191_T224_T0.5920.58
95_P539_Y0.5920.58
363_D370_Q0.5920.58
213_L257_A0.5910.58
419_D425_K0.5900.57
295_N382_F0.5900.57
513_D516_V0.5890.57
238_Q345_V0.5880.57
490_E528_W0.5870.57
38_A73_E0.5870.57
420_G499_N0.5860.57
304_L327_A0.5850.57
228_R231_F0.5840.57
407_P514_V0.5840.57
25_A51_V0.5820.56
12_G19_R0.5810.56
65_R70_V0.5810.56
421_I454_Q0.5800.56
303_H372_F0.5790.56
304_L330_E0.5790.56
420_G425_K0.5770.56
171_Y177_N0.5770.56
418_L454_Q0.5760.56
522_E527_N0.5760.56
241_E247_I0.5760.56
60_V239_L0.5750.56
222_L319_H0.5740.55
205_N219_G0.5740.55
56_F119_I0.5740.55
56_F59_I0.5730.55
109_S112_W0.5730.55
234_K238_Q0.5730.55
334_K369_D0.5730.55
290_S551_N0.5730.55
58_K61_K0.5700.55
134_M250_R0.5700.55
263_A339_H0.5700.55
392_I397_V0.5690.55
416_E425_K0.5680.55
321_A365_I0.5670.55
329_N358_E0.5670.55
41_N199_F0.5670.55
470_G554_G0.5670.55
272_T483_H0.5670.55
516_V523_K0.5670.55
266_M298_A0.5660.54
84_A87_H0.5660.54
196_S308_A0.5660.54
176_I184_L0.5650.54
330_E367_P0.5630.54
453_S457_G0.5600.54
231_F235_S0.5570.53
23_R230_E0.5560.53
60_V64_I0.5560.53
49_G125_I0.5550.53
346_T352_E0.5540.53
334_K340_L0.5540.53
502_H514_V0.5540.53
191_T225_S0.5540.53
475_A480_S0.5540.53
40_C78_G0.5540.53
135_R284_E0.5530.53
262_F290_S0.5530.53
172_Q422_I0.5510.52
269_G395_G0.5500.52
268_L318_L0.5500.52
12_G15_R0.5500.52
35_P240_M0.5490.52
210_A338_L0.5480.52
130_L211_L0.5480.52
253_V281_L0.5480.52
25_A70_V0.5480.52
344_T353_T0.5480.52
50_H80_D0.5460.52
217_G221_I0.5460.52
132_A138_I0.5450.52
133_A142_F0.5450.52
206_C315_I0.5440.52
411_F499_N0.5440.52
398_Q479_L0.5440.52
385_L494_L0.5430.51
275_V380_V0.5420.51
196_S314_F0.5420.51
44_I75_N0.5410.51
168_V181_L0.5400.51
38_A107_V0.5400.51
434_I476_S0.5400.51
222_L225_S0.5390.51
103_S107_V0.5380.51
389_G551_N0.5380.51
547_V554_G0.5370.51
329_N354_I0.5360.51
409_V428_E0.5360.51
108_V113_F0.5360.51
291_L389_G0.5350.50
239_L242_T0.5340.50
488_A494_L0.5330.50
120_P189_C0.5330.50
303_H376_G0.5320.50
523_K529_K0.5320.50
207_L219_G0.5320.50
392_I481_I0.5310.50
152_R156_G0.5310.50
404_H479_L0.5310.50
157_R312_D0.5310.50
525_K529_K0.5310.50
467_I503_I0.5300.50
267_A301_V0.5290.50
58_K73_E0.5290.50
541_A546_L0.5280.49
289_Y292_E0.5280.49
465_A479_L0.5280.49
243_I246_D0.5270.49
14_D172_Q0.5270.49
327_A365_I0.5260.49
257_A278_T0.5260.49
45_D51_V0.5260.49
379_A507_I0.5260.49
331_L338_L0.5260.49
180_E183_E0.5240.49
294_I380_V0.5240.49
39_V73_E0.5240.49
24_A29_E0.5230.49
384_N493_P0.5230.49
85_M199_F0.5230.49
104_V118_C0.5220.49
401_I479_L0.5220.49
234_K241_E0.5220.49
197_G449_L0.5200.48
179_N183_E0.5200.48
326_A362_Y0.5200.48
75_N119_I0.5200.48
290_S296_E0.5180.48
242_T251_D0.5180.48
138_I433_I0.5180.48
52_H223_A0.5180.48
40_C75_N0.5180.48
84_A93_S0.5170.48
100_I103_S0.5160.48
170_A173_A0.5160.48
147_P228_R0.5160.48
205_N228_R0.5150.48
160_S164_V0.5140.48
168_V450_A0.5140.48
434_I451_P0.5140.48
43_Y57_G0.5140.48
409_V416_E0.5130.48
77_I107_V0.5130.48
495_A514_V0.5130.48
218_N228_R0.5130.48
157_R160_S0.5120.47
397_V479_L0.5100.47
169_G457_G0.5100.47
342_A353_T0.5100.47
275_V378_L0.5100.47
219_G222_L0.5100.47
10_T72_F0.5090.47
128_G142_F0.5090.47
306_K372_F0.5090.47
144_S214_A0.5090.47
140_T213_L0.5080.47
163_S308_A0.5080.47
254_T287_V0.5080.47
61_K71_P0.5070.47
496_F529_K0.5070.47
255_V339_H0.5070.47
404_H465_A0.5060.47
259_D289_Y0.5060.47
222_L316_E0.5060.47
505_V512_L0.5050.46
85_M165_F0.5040.46
373_T402_T0.5040.46
132_A140_T0.5040.46
88_I112_W0.5030.46
266_M376_G0.5030.46
64_I240_M0.5030.46
418_L422_I0.5030.46
88_I91_R0.5030.46
161_L314_F0.5020.46
524_R527_N0.5020.46
27_V32_F0.5010.46
93_S449_L0.5010.46
256_K296_E0.5010.46
313_V372_F0.5000.46
340_L349_T0.5000.46
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gp4A 2 0.8548 100 0.09 Contact Map
2pcnA 3 0.2527 76.1 0.981 Contact Map
1q5xA 3 0.2509 69.1 0.982 Contact Map
3rfqA 5 0.233 65.9 0.982 Contact Map
1nxjA 3 0.2419 60.1 0.983 Contact Map
1j3lA 3 0.2581 57.1 0.983 Contact Map
3nojA 5 0.3602 55.9 0.983 Contact Map
1vi4A 1 0.2527 45.7 0.984 Contact Map
4lhbA 4 0.2366 44.5 0.984 Contact Map
3c8oA 4 0.2527 44 0.984 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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