PNP - BACSU - GREMLIN Contacts

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PNP - Polyribonucleotide nucleotidyltransferase

UniProt:	P50849	Sequences: MGQEKHVFTIDWAGRTLTVETGQLAKQANGAVMIRYGDTAVLSTATASKEPKPLDFFPLTVNYEERLYAVGKIPGGFIKREGRPSEKAVLASRLIDRPIRPLFADGFRNEVQVISIVMSVDQNCSSEMAAMFGSSLALSVSDIPFEGPIAGVTVGRIDDQFIINPTVDQLEKSDINLVVAGTKDAINMVEAGADEVPEEIMLEAIMFGHEEIKRLIAFQEEIVAAVGKEKSEIKLFEIDEELNEKVKALAEEDLLKAIQVHEKHAREDAINEVKNAVVAKFEDEEHDEDTIKQVKQILSKLVKNEVRRLITEEKVRPDGRGVDQIRPLSSEVGLLPRTHGSGLFTRGQTQALSVCTLGALGDVQILDGLGVEESKRFMHHYNFPQFSVGETGPMRGPGRREIGHGALGERALEPVIPSEKDFPYTVRLVSEVLESNGSTSQASICASTLAMMDAGVPIKAPVAGIAMGLVKSGEHYTVLTDIQGMEDALGDMDFKVAGTEKGVTALQMDIKIEGLSREILEEALQQAKKGRMEILNSMLATLSESRKELSRYAPKILTMTINPDKIRDVIGPSGKQINKIIEETGVKIDIEQDGTIFISSTDESGNQKAKKIIEDLVREVEVGQLYLGKVKRIEKFGAFVEIFSGKDGLVHISELALERVGKVEDVVKIGDEILVKVTEIDKQGRVNLSRKAVLREEKEKEEQQS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	705 (686)
Sequences:	2511 (1138)
Seq/√Len:	43.4

ECOLI - PNP
BACSU - PNP

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
253_D	276_A	5.219	1.00
537_S	540_A	4.805	1.00
183_K	220_E	4.699	1.00
561_I	569_V	4.691	1.00
355_C	450_A	4.546	1.00
321_G	324_Q	4.356	1.00
23_Q	331_E	4.020	1.00
655_L	667_V	3.939	1.00
460_A	501_K	3.864	1.00
629_K	672_E	3.613	1.00
323_D	529_K	3.576	1.00
351_A	432_V	3.339	1.00
627_L	674_L	3.225	1.00
627_L	672_E	3.164	1.00
247_K	304_N	3.154	1.00
43_S	115_S	3.129	1.00
161_F	203_E	3.098	1.00
156_R	174_D	3.028	1.00
333_G	453_D	2.883	1.00
328_L	537_S	2.788	1.00
480_T	530_G	2.786	1.00
500_E	539_L	2.776	1.00
312_E	475_H	2.767	1.00
43_S	133_G	2.761	1.00
211_E	214_R	2.753	1.00
166_T	169_Q	2.689	1.00
500_E	536_N	2.655	1.00
465_I	480_T	2.606	1.00
598_I	610_K	2.601	1.00
244_E	248_A	2.600	1.00
9_T	16_T	2.571	1.00
250_A	277_V	2.543	1.00
158_D	172_K	2.542	1.00
572_P	575_K	2.537	1.00
157_I	162_I	2.513	1.00
254_L	270_I	2.471	1.00
416_I	426_V	2.433	1.00
557_L	606_N	2.374	1.00
544_E	547_K	2.368	1.00
262_E	265_A	2.368	1.00
156_R	200_I	2.355	1.00
650_V	655_L	2.334	1.00
412_L	447_S	2.326	1.00
631_K	647_D	2.325	1.00
139_S	223_V	2.304	1.00
375_K	409_E	2.294	1.00
325_I	480_T	2.288	1.00
621_E	624_Q	2.274	1.00
611_K	615_D	2.233	1.00
418_S	421_D	2.226	1.00
353_S	446_A	2.216	1.00
579_K	583_E	2.179	1.00
668_K	671_D	2.163	1.00
690_R	694_L	2.155	1.00
525_Q	529_K	2.153	1.00
114_I	394_M	2.151	1.00
603_E	607_Q	2.143	1.00
560_T	595_T	2.103	0.99
631_K	641_E	2.098	0.99
17_L	36_Y	2.098	0.99
123_N	168_D	2.090	0.99
26_K	434_E	2.081	0.99
517_R	521_E	2.073	0.99
245_K	284_E	2.069	0.99
217_A	221_E	2.046	0.99
154_V	163_I	2.043	0.99
610_K	614_E	2.019	0.99
559_M	610_K	1.997	0.99
140_V	226_V	1.996	0.99
76_G	79_K	1.995	0.99
179_V	208_G	1.981	0.99
677_V	686_V	1.968	0.99
8_F	225_A	1.949	0.99
330_S	541_T	1.947	0.99
583_E	612_I	1.940	0.99
679_E	687_N	1.934	0.99
19_V	34_I	1.927	0.99
183_K	217_A	1.921	0.99
252_E	256_K	1.907	0.99
40_A	336_P	1.903	0.99
337_R	552_Y	1.900	0.99
453_D	546_R	1.898	0.99
311_T	475_H	1.895	0.99
29_N	142_D	1.890	0.99
528_K	532_M	1.890	0.99
37_G	121_D	1.889	0.99
607_Q	610_K	1.881	0.99
448_T	461_P	1.867	0.99
19_V	132_F	1.866	0.99
620_V	677_V	1.851	0.99
476_Y	522_E	1.848	0.99
448_T	539_L	1.844	0.99
116_I	386_F	1.839	0.99
608_K	611_K	1.838	0.99
275_N	279_A	1.838	0.99
655_L	660_V	1.836	0.99
146_E	513_E	1.824	0.98
160_Q	169_Q	1.823	0.98
415_V	458_I	1.821	0.98
640_V	650_V	1.816	0.98
359_A	599_S	1.807	0.98
249_L	280_K	1.804	0.98
585_G	605_G	1.790	0.98
654_E	692_A	1.784	0.98
34_I	133_G	1.777	0.98
155_G	173_S	1.773	0.98
186_I	205_I	1.773	0.98
197_P	200_I	1.765	0.98
9_T	18_T	1.764	0.98
322_V	477_T	1.757	0.98
461_P	539_L	1.755	0.98
269_A	272_E	1.748	0.98
24_L	433_L	1.730	0.98
411_A	505_A	1.726	0.98
308_R	312_E	1.717	0.98
662_K	665_D	1.701	0.98
460_A	500_E	1.682	0.97
353_S	428_L	1.676	0.97
568_D	616_L	1.664	0.97
268_D	272_E	1.660	0.97
32_V	136_L	1.658	0.97
325_I	533_E	1.649	0.97
650_V	667_V	1.644	0.97
206_M	517_R	1.639	0.97
673_I	690_R	1.631	0.97
156_R	161_F	1.627	0.97
247_K	251_E	1.618	0.97
355_C	428_L	1.611	0.97
132_F	215_L	1.609	0.97
99_I	138_L	1.609	0.97
40_A	335_L	1.601	0.96
272_E	276_A	1.594	0.96
154_V	207_F	1.594	0.96
174_D	194_D	1.578	0.96
354_V	431_E	1.576	0.96
652_I	663_V	1.573	0.96
240_E	244_E	1.566	0.96
392_G	395_R	1.566	0.96
8_F	222_I	1.555	0.96
11_D	16_T	1.552	0.96
635_K	664_E	1.550	0.96
607_Q	611_K	1.546	0.96
19_V	136_L	1.543	0.96
185_A	514_G	1.543	0.96
168_D	171_E	1.537	0.95
618_R	624_Q	1.534	0.95
557_L	610_K	1.528	0.95
35_R	38_D	1.525	0.95
153_T	176_N	1.518	0.95
215_L	219_Q	1.513	0.95
555_K	600_S	1.509	0.95
355_C	454_A	1.509	0.95
598_I	613_I	1.509	0.95
47_A	143_I	1.506	0.95
591_E	595_T	1.497	0.95
385_Q	394_M	1.496	0.95
689_S	692_A	1.496	0.95
539_L	543_S	1.495	0.95
8_F	221_E	1.491	0.95
648_G	688_L	1.490	0.95
657_L	693_V	1.490	0.95
181_G	212_I	1.489	0.95
127_E	153_T	1.488	0.95
330_S	537_S	1.478	0.94
656_A	690_R	1.472	0.94
163_I	207_F	1.465	0.94
471_K	512_I	1.462	0.94
11_D	14_G	1.456	0.94
257_A	273_V	1.452	0.94
559_M	598_I	1.448	0.94
245_K	249_L	1.442	0.94
608_K	612_I	1.430	0.93
329_S	343_L	1.428	0.93
533_E	537_S	1.427	0.93
681_D	685_R	1.414	0.93
242_L	297_I	1.411	0.93
600_S	606_N	1.411	0.93
323_D	526_Q	1.410	0.93
191_A	506_L	1.406	0.93
131_M	149_I	1.397	0.93
47_A	231_S	1.395	0.92
572_P	576_Q	1.384	0.92
415_V	462_V	1.382	0.92
642_I	686_V	1.381	0.92
441_Q	444_I	1.379	0.92
10_I	17_L	1.366	0.92
253_D	256_K	1.365	0.92
142_D	231_S	1.364	0.92
633_I	663_V	1.364	0.92
47_A	107_F	1.363	0.92
136_L	222_I	1.362	0.92
325_I	465_I	1.360	0.91
584_T	608_K	1.344	0.91
641_E	647_D	1.342	0.91
107_F	231_S	1.338	0.91
632_R	685_R	1.338	0.91
576_Q	616_L	1.335	0.91
34_I	129_A	1.335	0.91
379_H	447_S	1.332	0.91
15_R	36_Y	1.330	0.91
199_E	521_E	1.320	0.90
537_S	541_T	1.318	0.90
584_T	612_I	1.311	0.90
115_S	130_A	1.309	0.90
107_F	111_V	1.307	0.90
379_H	443_S	1.305	0.90
600_S	605_G	1.301	0.90
175_I	196_V	1.298	0.89
105_D	303_K	1.297	0.89
7_V	18_T	1.297	0.89
625_L	693_V	1.292	0.89
363_V	374_S	1.285	0.89
278_V	295_K	1.285	0.89
338_T	354_V	1.284	0.89
139_S	219_Q	1.284	0.89
197_P	503_V	1.273	0.88
161_F	200_I	1.271	0.88
620_V	642_I	1.260	0.88
352_L	433_L	1.259	0.88
602_D	605_G	1.255	0.88
19_V	32_V	1.255	0.88
596_I	613_I	1.244	0.87
168_D	172_K	1.243	0.87
317_P	485_M	1.234	0.87
61_V	95_I	1.229	0.87
99_I	134_S	1.229	0.87
36_Y	129_A	1.229	0.87
267_E	271_N	1.226	0.87
68_Y	429_V	1.219	0.86
120_V	126_S	1.217	0.86
223_V	227_G	1.217	0.86
632_R	669_I	1.216	0.86
569_V	596_I	1.211	0.86
18_T	35_R	1.197	0.85
314_K	475_H	1.196	0.85
229_E	232_E	1.195	0.85
604_S	608_K	1.189	0.85
660_V	665_D	1.189	0.85
274_K	295_K	1.189	0.85
351_A	442_A	1.183	0.84
452_M	458_I	1.182	0.84
29_N	46_T	1.181	0.84
131_M	151_G	1.181	0.84
536_N	540_A	1.179	0.84
44_T	385_Q	1.170	0.84
377_F	447_S	1.167	0.84
33_M	118_M	1.163	0.83
199_E	525_Q	1.161	0.83
462_V	499_T	1.156	0.83
581_I	586_V	1.153	0.83
106_G	235_L	1.151	0.83
194_D	414_P	1.149	0.83
260_V	269_A	1.141	0.82
525_Q	528_K	1.140	0.82
246_V	277_V	1.139	0.82
243_N	247_K	1.138	0.82
106_G	233_I	1.136	0.82
351_A	446_A	1.135	0.82
72_K	79_K	1.130	0.82
641_E	644_S	1.129	0.82
239_D	293_Q	1.129	0.82
650_V	693_V	1.128	0.82
277_V	298_L	1.128	0.82
307_R	491_D	1.128	0.82
39_T	126_S	1.126	0.81
273_V	276_A	1.125	0.81
604_S	607_Q	1.124	0.81
250_A	273_V	1.122	0.81
64_E	88_A	1.120	0.81
251_E	255_L	1.115	0.81
533_E	536_N	1.114	0.81
47_A	111_V	1.108	0.80
633_I	669_I	1.104	0.80
199_E	203_E	1.104	0.80
444_I	497_A	1.102	0.80
220_E	224_A	1.100	0.80
189_V	508_M	1.100	0.80
174_D	200_I	1.100	0.80
162_I	169_Q	1.100	0.80
569_V	572_P	1.098	0.80
161_F	207_F	1.098	0.80
448_T	452_M	1.097	0.80
57_F	111_V	1.097	0.80
19_V	222_I	1.096	0.80
612_I	615_D	1.092	0.79
467_M	478_V	1.091	0.79
655_L	666_V	1.088	0.79
159_D	174_D	1.088	0.79
255_L	259_Q	1.088	0.79
471_K	476_Y	1.087	0.79
383_F	387_S	1.087	0.79
530_G	533_E	1.082	0.79
611_K	614_E	1.082	0.79
118_M	352_L	1.073	0.78
306_V	310_I	1.072	0.78
201_M	503_V	1.071	0.78
151_G	180_A	1.071	0.78
142_D	230_K	1.071	0.78
642_I	677_V	1.070	0.78
652_I	662_K	1.070	0.78
428_L	450_A	1.070	0.78
386_F	433_L	1.070	0.78
246_V	250_A	1.069	0.78
142_D	228_K	1.068	0.78
254_L	305_E	1.067	0.78
87_K	91_A	1.065	0.78
195_E	460_A	1.065	0.78
430_S	446_A	1.060	0.77
17_L	132_F	1.059	0.77
24_L	343_L	1.051	0.77
458_I	461_P	1.051	0.77
29_N	47_A	1.050	0.77
569_V	576_Q	1.048	0.76
213_K	217_A	1.043	0.76
376_R	419_E	1.041	0.76
565_K	619_E	1.036	0.76
466_A	478_V	1.035	0.76
415_V	460_A	1.035	0.76
249_L	281_F	1.032	0.75
254_L	298_L	1.031	0.75
620_V	643_F	1.031	0.75
638_A	667_V	1.030	0.75
290_T	293_Q	1.029	0.75
21_T	136_L	1.029	0.75
480_T	533_E	1.028	0.75
31_A	44_T	1.027	0.75
12_W	17_L	1.024	0.75
38_D	337_R	1.024	0.75
548_E	603_E	1.013	0.74
580_I	612_I	1.008	0.74
119_S	338_T	1.002	0.73
334_L	343_L	1.002	0.73
19_V	218_F	1.002	0.73
54_L	108_R	1.001	0.73
280_K	284_E	1.001	0.73
643_F	646_K	1.000	0.73
332_V	453_D	0.999	0.73
335_L	354_V	0.996	0.73
358_G	362_D	0.991	0.72
655_L	663_V	0.990	0.72
20_E	35_R	0.988	0.72
360_L	363_V	0.988	0.72
249_L	277_V	0.986	0.72
175_I	204_A	0.986	0.72
398_G	401_E	0.984	0.72
569_V	613_I	0.983	0.72
622_V	679_E	0.983	0.72
434_E	439_T	0.982	0.72
412_L	451_M	0.981	0.72
556_I	599_S	0.980	0.71
30_G	45_A	0.979	0.71
654_E	691_K	0.979	0.71
353_S	379_H	0.977	0.71
33_M	40_A	0.975	0.71
628_G	640_V	0.975	0.71
259_Q	309_L	0.974	0.71
674_L	693_V	0.974	0.71
314_K	477_T	0.972	0.71
40_A	338_T	0.971	0.71
337_R	550_S	0.968	0.71
115_S	134_S	0.966	0.70
311_T	477_T	0.963	0.70
47_A	142_D	0.962	0.70
660_V	667_V	0.962	0.70
382_N	429_V	0.961	0.70
328_L	530_G	0.959	0.70
542_L	546_R	0.959	0.70
245_K	248_A	0.955	0.69
218_F	222_I	0.952	0.69
342_G	432_V	0.950	0.69
363_V	425_T	0.950	0.69
422_F	457_P	0.949	0.69
656_A	660_V	0.948	0.69
449_L	453_D	0.946	0.69
449_L	542_L	0.944	0.69
195_E	415_V	0.944	0.69
305_E	308_R	0.944	0.69
25_A	42_L	0.943	0.68
98_P	180_A	0.941	0.68
238_I	243_N	0.941	0.68
110_E	393_P	0.940	0.68
633_I	667_V	0.939	0.68
62_N	89_V	0.939	0.68
41_V	115_S	0.938	0.68
569_V	616_L	0.937	0.68
253_D	273_V	0.934	0.68
208_G	211_E	0.933	0.68
332_V	542_L	0.931	0.68
258_I	305_E	0.930	0.67
559_M	613_I	0.930	0.67
279_A	283_D	0.929	0.67
115_S	133_G	0.927	0.67
365_I	374_S	0.926	0.67
579_K	612_I	0.925	0.67
586_V	605_G	0.925	0.67
195_E	501_K	0.922	0.67
314_K	322_V	0.920	0.67
210_E	213_K	0.916	0.66
650_V	690_R	0.916	0.66
198_E	528_K	0.915	0.66
300_K	303_K	0.914	0.66
568_D	576_Q	0.911	0.66
237_E	240_E	0.910	0.66
24_L	40_A	0.907	0.65
54_L	57_F	0.907	0.65
192_G	410_R	0.905	0.65
242_L	246_V	0.901	0.65
156_R	175_I	0.898	0.65
274_K	298_L	0.896	0.65
518_E	522_E	0.895	0.64
578_N	582_E	0.894	0.64
240_E	243_N	0.893	0.64
214_R	217_A	0.889	0.64
618_R	643_F	0.888	0.64
332_V	541_T	0.885	0.64
112_Q	391_T	0.884	0.63
580_I	586_V	0.883	0.63
83_R	89_V	0.881	0.63
408_G	444_I	0.881	0.63
628_G	688_L	0.880	0.63
47_A	109_N	0.880	0.63
562_N	619_E	0.879	0.63
66_R	431_E	0.879	0.63
387_S	439_T	0.879	0.63
463_A	532_M	0.878	0.63
375_K	406_A	0.877	0.63
530_G	537_S	0.876	0.63
227_G	230_K	0.876	0.63
657_L	694_L	0.875	0.63
63_Y	130_A	0.874	0.63
145_F	148_P	0.872	0.62
330_S	449_L	0.872	0.62
286_H	289_D	0.870	0.62
157_I	172_K	0.870	0.62
10_I	218_F	0.869	0.62
95_I	115_S	0.868	0.62
28_A	46_T	0.868	0.62
213_K	216_I	0.867	0.62
220_E	223_V	0.862	0.61
559_M	596_I	0.860	0.61
68_Y	431_E	0.860	0.61
660_V	663_V	0.852	0.61
558_T	595_T	0.849	0.60
57_F	109_N	0.849	0.60
217_A	220_E	0.845	0.60
569_V	617_V	0.844	0.60
192_G	406_A	0.841	0.60
45_A	133_G	0.841	0.60
463_A	539_L	0.841	0.60
388_V	392_G	0.840	0.59
428_L	447_S	0.839	0.59
255_L	313_E	0.839	0.59
63_Y	88_A	0.839	0.59
91_A	125_S	0.837	0.59
448_T	538_M	0.836	0.59
256_K	269_A	0.834	0.59
189_V	466_A	0.834	0.59
516_S	519_I	0.834	0.59
332_V	546_R	0.832	0.59
185_A	189_V	0.832	0.59
278_V	282_E	0.831	0.59
243_N	297_I	0.828	0.58
247_K	301_L	0.827	0.58
262_E	348_Q	0.827	0.58
634_E	639_F	0.826	0.58
161_F	204_A	0.825	0.58
283_D	286_H	0.824	0.58
127_E	178_V	0.824	0.58
45_A	137_A	0.823	0.58
328_L	533_E	0.823	0.58
200_I	203_E	0.822	0.58
689_S	693_V	0.821	0.58
658_E	661_G	0.819	0.58
555_K	605_G	0.818	0.57
628_G	648_G	0.818	0.57
677_V	680_I	0.816	0.57
561_I	588_I	0.815	0.57
272_E	275_N	0.813	0.57
630_V	667_V	0.813	0.57
141_S	230_K	0.812	0.57
641_E	645_G	0.811	0.57
279_A	282_E	0.810	0.57
261_H	265_A	0.808	0.56
121_D	124_C	0.807	0.56
594_G	598_I	0.806	0.56
259_Q	313_E	0.805	0.56
580_I	609_A	0.804	0.56
560_T	593_D	0.803	0.56
355_C	446_A	0.803	0.56
209_H	213_K	0.802	0.56
638_A	663_V	0.802	0.56
88_A	379_H	0.802	0.56
206_M	521_E	0.801	0.56
629_K	641_E	0.800	0.56
385_Q	396_G	0.798	0.56
299_S	302_V	0.798	0.56
150_A	515_L	0.798	0.56
245_K	281_F	0.797	0.55
667_V	673_I	0.796	0.55
310_I	470_V	0.796	0.55
12_W	215_L	0.795	0.55
92_S	617_V	0.795	0.55
562_N	568_D	0.794	0.55
21_T	226_V	0.793	0.55
83_R	396_G	0.793	0.55
453_D	542_L	0.793	0.55
632_R	687_N	0.792	0.55
265_A	268_D	0.786	0.54
15_R	124_C	0.786	0.54
239_D	290_T	0.784	0.54
32_V	222_I	0.783	0.54
549_L	555_K	0.783	0.54
257_A	270_I	0.783	0.54
353_S	377_F	0.782	0.54
689_S	694_L	0.781	0.54
38_D	551_R	0.781	0.54
150_A	207_F	0.781	0.54
221_E	225_A	0.780	0.54
15_R	169_Q	0.780	0.54
43_S	134_S	0.779	0.54
46_T	112_Q	0.777	0.54
21_T	32_V	0.775	0.53
572_P	596_I	0.775	0.53
634_E	669_I	0.774	0.53
650_V	673_I	0.773	0.53
128_M	132_F	0.773	0.53
260_V	265_A	0.773	0.53
206_M	210_E	0.770	0.53
276_A	279_A	0.770	0.53
276_A	280_K	0.768	0.53
353_S	432_V	0.767	0.53
45_A	143_I	0.766	0.53
255_L	305_E	0.764	0.52
57_F	108_R	0.763	0.52
640_V	655_L	0.762	0.52
41_V	95_I	0.762	0.52
265_A	269_A	0.762	0.52
636_F	649_L	0.761	0.52
250_A	281_F	0.759	0.52
378_M	416_I	0.758	0.52
416_I	451_M	0.758	0.52
105_D	654_E	0.757	0.52
48_S	54_L	0.756	0.52
62_N	92_S	0.754	0.51
345_T	434_E	0.752	0.51
377_F	413_E	0.751	0.51
177_L	196_V	0.751	0.51
250_A	253_D	0.747	0.51
296_Q	299_S	0.746	0.51
73_I	378_M	0.746	0.51
310_I	317_P	0.744	0.50
365_I	372_E	0.743	0.50
34_I	41_V	0.742	0.50
51_P	54_L	0.741	0.50
458_I	683_Q	0.738	0.50
31_A	42_L	0.738	0.50
654_E	678_T	0.737	0.50
566_I	590_I	0.735	0.50
23_Q	33_M	0.735	0.50
26_K	345_T	0.734	0.49
210_E	517_R	0.733	0.49
135_S	148_P	0.733	0.49
576_Q	579_K	0.733	0.49
360_L	425_T	0.732	0.49
588_I	613_I	0.731	0.49
342_G	449_L	0.731	0.49
44_T	114_I	0.730	0.49
421_D	459_K	0.730	0.49
105_D	299_S	0.730	0.49
422_F	456_V	0.729	0.49
13_A	17_L	0.728	0.49
77_F	365_I	0.727	0.49
522_E	526_Q	0.725	0.49
453_D	584_T	0.724	0.48
309_L	313_E	0.724	0.48
285_E	294_V	0.724	0.48
451_M	456_V	0.722	0.48
636_F	639_F	0.722	0.48
406_A	409_E	0.721	0.48
24_L	352_L	0.721	0.48
111_V	231_S	0.720	0.48
77_F	367_D	0.720	0.48
679_E	682_K	0.719	0.48
64_E	114_I	0.718	0.48
628_G	647_D	0.718	0.48
87_K	125_S	0.718	0.48
244_E	247_K	0.717	0.48
452_M	542_L	0.717	0.48
51_P	109_N	0.716	0.48
118_M	431_E	0.714	0.48
189_V	506_L	0.714	0.48
198_E	531_R	0.713	0.47
11_D	15_R	0.713	0.47
408_G	441_Q	0.712	0.47
241_E	244_E	0.712	0.47
565_K	568_D	0.710	0.47
676_K	691_K	0.710	0.47
328_L	536_N	0.709	0.47
243_N	300_K	0.707	0.47
34_I	132_F	0.705	0.47
448_T	458_I	0.703	0.46
92_S	398_G	0.703	0.46
476_Y	518_E	0.701	0.46
79_K	85_S	0.701	0.46
184_D	513_E	0.699	0.46
27_Q	434_E	0.699	0.46
550_S	553_A	0.698	0.46
21_T	222_I	0.698	0.46
274_K	299_S	0.698	0.46
255_L	309_L	0.697	0.46
478_V	522_E	0.697	0.46
45_A	134_S	0.696	0.46
559_M	617_V	0.696	0.46
636_F	647_D	0.695	0.46
449_L	585_G	0.694	0.46
152_V	215_L	0.693	0.46
78_I	86_E	0.693	0.46
153_T	441_Q	0.693	0.46
476_Y	519_I	0.692	0.45
160_Q	232_E	0.691	0.45
205_I	520_L	0.691	0.45
467_M	508_M	0.690	0.45
250_A	254_L	0.690	0.45
91_A	127_E	0.689	0.45
299_S	488_A	0.689	0.45
428_L	458_I	0.684	0.45
157_I	173_S	0.684	0.45
580_I	584_T	0.682	0.44
114_I	385_Q	0.682	0.44
106_G	293_Q	0.682	0.44
351_A	379_H	0.682	0.44
605_G	608_K	0.682	0.44
625_L	676_K	0.682	0.44
153_T	178_V	0.681	0.44
267_E	388_V	0.681	0.44
510_I	519_I	0.680	0.44
256_K	259_Q	0.678	0.44
663_V	666_V	0.678	0.44
500_E	532_M	0.676	0.44
202_L	524_L	0.675	0.44
152_V	163_I	0.675	0.44
132_F	136_L	0.675	0.44
655_L	673_I	0.674	0.44
160_Q	203_E	0.673	0.44
466_A	489_L	0.673	0.44
628_G	652_I	0.673	0.44
36_Y	124_C	0.672	0.44
561_I	566_I	0.671	0.43
63_Y	126_S	0.670	0.43
112_Q	393_P	0.670	0.43
149_I	273_V	0.669	0.43
136_L	219_Q	0.669	0.43
624_Q	646_K	0.669	0.43
584_T	588_I	0.668	0.43
64_E	397_P	0.668	0.43
586_V	600_S	0.667	0.43
29_N	231_S	0.667	0.43
293_Q	297_I	0.666	0.43
376_R	425_T	0.664	0.43
112_Q	394_M	0.663	0.43
638_A	666_V	0.662	0.43
467_M	527_A	0.662	0.43
248_A	252_E	0.662	0.43
678_T	687_N	0.660	0.42
17_L	218_F	0.660	0.42
212_I	216_I	0.659	0.42
314_K	323_D	0.658	0.42
151_G	205_I	0.658	0.42
614_E	618_R	0.658	0.42
452_M	546_R	0.657	0.42
268_D	271_N	0.657	0.42
353_S	448_T	0.656	0.42
567_R	572_P	0.656	0.42
264_H	267_E	0.656	0.42
84_P	396_G	0.656	0.42
196_V	200_I	0.656	0.42
10_I	214_R	0.655	0.42
391_T	395_R	0.655	0.42
632_R	635_K	0.655	0.42
595_T	598_I	0.653	0.42
378_M	425_T	0.653	0.42
259_Q	315_V	0.653	0.42
602_D	607_Q	0.652	0.42
55_D	488_A	0.652	0.42
467_M	526_Q	0.651	0.42
521_E	525_Q	0.650	0.42
621_E	626_Y	0.650	0.42
12_W	132_F	0.648	0.41
363_V	419_E	0.648	0.41
271_N	275_N	0.647	0.41
111_V	143_I	0.647	0.41
586_V	612_I	0.646	0.41
95_I	130_A	0.646	0.41
325_I	537_S	0.646	0.41
62_N	408_G	0.646	0.41
72_K	76_G	0.645	0.41
195_E	499_T	0.644	0.41
32_V	137_A	0.643	0.41
581_I	596_I	0.643	0.41
128_M	178_V	0.642	0.41
496_V	523_A	0.642	0.41
30_G	137_A	0.641	0.41
411_A	504_T	0.641	0.41
615_D	618_R	0.641	0.41
600_S	603_E	0.640	0.41
280_K	386_F	0.639	0.40
557_L	598_I	0.638	0.40
415_V	499_T	0.638	0.40
625_L	674_L	0.638	0.40
50_E	295_K	0.637	0.40
334_L	352_L	0.637	0.40
152_V	181_G	0.636	0.40
441_Q	497_A	0.634	0.40
41_V	128_M	0.634	0.40
175_I	200_I	0.633	0.40
170_L	176_N	0.633	0.40
616_L	620_V	0.633	0.40
72_K	77_F	0.632	0.40
413_E	416_I	0.631	0.40
385_Q	391_T	0.631	0.40
638_A	659_R	0.631	0.40
149_I	180_A	0.630	0.40
82_G	397_P	0.629	0.40
62_N	396_G	0.628	0.39
605_G	609_A	0.628	0.39
205_I	208_G	0.628	0.39
532_M	536_N	0.626	0.39
556_I	597_F	0.626	0.39
557_L	607_Q	0.625	0.39
109_N	231_S	0.625	0.39
52_K	105_D	0.625	0.39
353_S	447_S	0.624	0.39
23_Q	334_L	0.624	0.39
396_G	672_E	0.624	0.39
30_G	140_V	0.623	0.39
183_K	213_K	0.622	0.39
105_D	488_A	0.622	0.39
638_A	665_D	0.621	0.39
64_E	116_I	0.619	0.39
518_E	521_E	0.618	0.39
516_S	520_L	0.618	0.39
62_N	393_P	0.618	0.39
132_F	150_A	0.618	0.39
674_L	690_R	0.618	0.39
156_R	196_V	0.618	0.39
33_M	42_L	0.616	0.38
656_A	666_V	0.616	0.38
564_D	567_R	0.616	0.38
581_I	589_D	0.616	0.38
297_I	301_L	0.616	0.38
258_I	317_P	0.616	0.38
428_L	451_M	0.615	0.38
204_A	208_G	0.615	0.38
64_E	379_H	0.614	0.38
536_N	539_L	0.614	0.38
632_R	677_V	0.614	0.38
690_R	693_V	0.614	0.38
618_R	626_Y	0.614	0.38
383_F	388_V	0.613	0.38
306_V	317_P	0.612	0.38
62_N	398_G	0.612	0.38
30_G	228_K	0.611	0.38
496_V	527_A	0.611	0.38
17_L	124_C	0.610	0.38
136_L	140_V	0.610	0.38
385_Q	392_G	0.609	0.38
212_I	215_L	0.609	0.38
273_V	298_L	0.608	0.38
615_D	643_F	0.608	0.38
179_V	205_I	0.608	0.38
77_F	118_M	0.607	0.38
145_F	219_Q	0.605	0.37
659_R	665_D	0.604	0.37
633_I	636_F	0.603	0.37
78_I	368_G	0.603	0.37
359_A	555_K	0.603	0.37
397_P	402_I	0.602	0.37
252_E	255_L	0.600	0.37
87_K	92_S	0.600	0.37
647_D	677_V	0.600	0.37
632_R	639_F	0.600	0.37
78_I	687_N	0.600	0.37
642_I	647_D	0.600	0.37
37_G	124_C	0.599	0.37
14_G	169_Q	0.598	0.37
158_D	171_E	0.597	0.37
656_A	693_V	0.597	0.37
142_D	227_G	0.595	0.37
452_M	539_L	0.595	0.37
291_I	295_K	0.593	0.36
317_P	483_Q	0.593	0.36
676_K	692_A	0.592	0.36
110_E	526_Q	0.592	0.36
333_G	446_A	0.592	0.36
159_D	200_I	0.592	0.36
615_D	644_S	0.591	0.36
583_E	608_K	0.591	0.36
73_I	76_G	0.589	0.36
243_N	246_V	0.589	0.36
203_E	517_R	0.588	0.36
342_G	446_A	0.587	0.36
667_V	671_D	0.586	0.36
221_E	224_A	0.586	0.36
201_M	204_A	0.586	0.36
135_S	150_A	0.585	0.36
411_A	497_A	0.585	0.36
70_V	122_Q	0.585	0.36
277_V	281_F	0.585	0.36
333_G	546_R	0.585	0.36
672_E	687_N	0.584	0.36
12_W	152_V	0.583	0.35
29_N	44_T	0.583	0.35
412_L	416_I	0.582	0.35
117_V	388_V	0.581	0.35
329_S	537_S	0.581	0.35
488_A	515_L	0.581	0.35
442_A	463_A	0.581	0.35
189_V	467_M	0.579	0.35
376_R	416_I	0.578	0.35
642_I	688_L	0.578	0.35
510_I	516_S	0.577	0.35
432_V	439_T	0.577	0.35
441_Q	555_K	0.577	0.35
251_E	305_E	0.576	0.35
551_R	555_K	0.576	0.35
270_I	560_T	0.576	0.35
358_G	425_T	0.576	0.35
314_K	522_E	0.576	0.35
238_I	300_K	0.576	0.35
219_Q	225_A	0.576	0.35
222_I	225_A	0.576	0.35
242_L	294_V	0.576	0.35
134_S	149_I	0.575	0.35
545_S	549_L	0.573	0.35
179_V	410_R	0.573	0.35
254_L	292_K	0.572	0.34
140_V	143_I	0.572	0.34
631_K	639_F	0.572	0.34
328_L	442_A	0.571	0.34
49_K	271_N	0.571	0.34
189_V	489_L	0.571	0.34
245_K	285_E	0.571	0.34
27_Q	439_T	0.568	0.34
656_A	686_V	0.568	0.34
136_L	218_F	0.567	0.34
584_T	609_A	0.567	0.34
45_A	89_V	0.566	0.34
297_I	300_K	0.565	0.34
348_Q	436_N	0.565	0.34
678_T	689_S	0.564	0.34
526_Q	529_K	0.564	0.34
254_L	273_V	0.563	0.34
170_L	173_S	0.563	0.34
409_E	413_E	0.563	0.34
116_I	431_E	0.562	0.34
563_P	581_I	0.562	0.34
314_K	476_Y	0.562	0.34
46_T	443_S	0.561	0.34
601_T	606_N	0.561	0.34
42_L	116_I	0.560	0.33
125_S	281_F	0.560	0.33
667_V	693_V	0.560	0.33
324_Q	614_E	0.560	0.33
515_L	520_L	0.560	0.33
152_V	212_I	0.560	0.33
91_A	149_I	0.559	0.33
599_S	606_N	0.559	0.33
569_V	588_I	0.559	0.33
634_E	649_L	0.558	0.33
258_I	306_V	0.558	0.33
379_H	432_V	0.558	0.33
50_E	53_P	0.558	0.33
49_K	268_D	0.558	0.33
301_L	305_E	0.557	0.33
99_I	149_I	0.557	0.33
596_I	599_S	0.557	0.33
204_A	439_T	0.556	0.33
228_K	625_L	0.556	0.33
17_L	215_L	0.556	0.33
278_V	291_I	0.555	0.33
620_V	646_K	0.555	0.33
676_K	689_S	0.554	0.33
38_D	550_S	0.554	0.33
191_A	485_M	0.554	0.33
489_L	512_I	0.554	0.33
633_I	652_I	0.553	0.33
250_A	298_L	0.552	0.33
46_T	114_I	0.552	0.33
638_A	652_I	0.552	0.33
8_F	218_F	0.552	0.33
448_T	542_L	0.551	0.33
67_L	369_L	0.551	0.33
140_V	229_E	0.550	0.33
28_A	31_A	0.550	0.33
247_K	250_A	0.550	0.33
652_I	659_R	0.549	0.33
325_I	463_A	0.548	0.32
68_Y	382_N	0.547	0.32
233_I	236_F	0.546	0.32
580_I	608_K	0.545	0.32
595_T	599_S	0.544	0.32
586_V	613_I	0.544	0.32
24_L	33_M	0.544	0.32
43_S	92_S	0.543	0.32
411_A	641_E	0.543	0.32
156_R	203_E	0.542	0.32
406_A	413_E	0.542	0.32
89_V	439_T	0.541	0.32
530_G	557_L	0.539	0.32
114_I	386_F	0.539	0.32
40_A	118_M	0.539	0.32
179_V	189_V	0.539	0.32
192_G	413_E	0.538	0.32
471_K	474_E	0.537	0.32
626_Y	649_L	0.537	0.32
533_E	540_A	0.537	0.32
630_V	638_A	0.537	0.32
299_S	303_K	0.536	0.31
246_V	265_A	0.536	0.31
207_F	211_E	0.534	0.31
635_K	679_E	0.534	0.31
658_E	666_V	0.533	0.31
466_A	526_Q	0.533	0.31
328_L	465_I	0.532	0.31
446_A	449_L	0.532	0.31
432_V	443_S	0.532	0.31
142_D	258_I	0.532	0.31
607_Q	614_E	0.531	0.31
89_V	556_I	0.531	0.31
428_L	454_A	0.531	0.31
241_E	245_K	0.531	0.31
31_A	118_M	0.531	0.31
46_T	116_I	0.530	0.31
185_A	209_H	0.530	0.31
267_E	348_Q	0.530	0.31
594_G	601_T	0.530	0.31
351_A	430_S	0.529	0.31
25_A	44_T	0.528	0.31
146_E	227_G	0.528	0.31
664_E	668_K	0.528	0.31
251_E	301_L	0.528	0.31
8_F	19_V	0.528	0.31
246_V	249_L	0.527	0.31
246_V	281_F	0.526	0.31
70_V	369_L	0.526	0.31
117_V	550_S	0.526	0.31
266_R	483_Q	0.526	0.31
624_Q	642_I	0.526	0.31
35_R	124_C	0.526	0.31
325_I	538_M	0.526	0.31
277_V	280_K	0.524	0.30
119_S	563_P	0.524	0.30
77_F	629_K	0.524	0.30
282_E	294_V	0.524	0.30
319_G	480_T	0.524	0.30
182_T	515_L	0.522	0.30
361_G	589_D	0.522	0.30
441_Q	578_N	0.522	0.30
654_E	687_N	0.522	0.30
633_I	671_D	0.522	0.30
68_Y	354_V	0.522	0.30
189_V	520_L	0.522	0.30
360_L	419_E	0.521	0.30
244_E	256_K	0.521	0.30
46_T	391_T	0.521	0.30
88_A	371_V	0.520	0.30
306_V	489_L	0.520	0.30
580_I	600_S	0.519	0.30
680_I	686_V	0.519	0.30
342_G	379_H	0.519	0.30
557_L	600_S	0.519	0.30
143_I	230_K	0.519	0.30
35_R	40_A	0.518	0.30
210_E	214_R	0.518	0.30
472_S	475_H	0.518	0.30
281_F	285_E	0.518	0.30
45_A	138_L	0.517	0.30
327_P	530_G	0.517	0.30
198_E	532_M	0.516	0.30
21_T	24_L	0.516	0.30
94_L	178_V	0.515	0.30
559_M	614_E	0.515	0.30
576_Q	617_V	0.515	0.30
291_I	294_V	0.515	0.30
599_S	616_L	0.515	0.30
642_I	683_Q	0.515	0.30
139_S	220_E	0.515	0.30
107_F	145_F	0.514	0.30
377_F	450_A	0.514	0.30
525_Q	532_M	0.513	0.30
604_S	611_K	0.513	0.30
323_D	522_E	0.513	0.30
377_F	434_E	0.513	0.30
132_F	218_F	0.513	0.30
359_A	425_T	0.512	0.30
16_T	470_V	0.512	0.30
526_Q	530_G	0.512	0.30
107_F	232_E	0.511	0.29
195_E	504_T	0.511	0.29
503_V	532_M	0.511	0.29
13_A	590_I	0.510	0.29
52_K	62_N	0.510	0.29
112_Q	392_G	0.509	0.29
556_I	610_K	0.509	0.29
113_V	245_K	0.508	0.29
139_S	147_G	0.507	0.29
594_G	599_S	0.507	0.29
662_K	666_V	0.506	0.29
654_E	679_E	0.506	0.29
358_G	538_M	0.506	0.29
286_H	294_V	0.506	0.29
224_A	272_E	0.506	0.29
60_T	110_E	0.506	0.29
13_A	211_E	0.505	0.29
88_A	687_N	0.505	0.29
409_E	443_S	0.504	0.29
204_A	573_S	0.504	0.29
485_M	687_N	0.504	0.29
281_F	286_H	0.504	0.29
328_L	470_V	0.504	0.29
483_Q	489_L	0.504	0.29
461_P	500_E	0.503	0.29
258_I	270_I	0.503	0.29
317_P	578_N	0.502	0.29
608_K	629_K	0.501	0.29
622_V	680_I	0.501	0.29
86_E	245_K	0.501	0.29
48_S	108_R	0.500	0.29
154_V	161_F	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4nbqA	3	0.9631	100	0.295	Contact Map
3cdiA	3	0.7305	100	0.3	Contact Map
1e3pA	3	0.8738	100	0.327	Contact Map
4aidA	3	0.8014	100	0.341	Contact Map
3u1kA	3	0.8624	100	0.41	Contact Map
3gmeA	3	0.6823	100	0.44	Contact Map
2nn6A	1	0.383	100	0.799	Contact Map
2nn6B	1	0.3291	100	0.83	Contact Map
2je6B	2	0.3277	100	0.833	Contact Map
2po1A	1	0.3305	100	0.834	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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