GREMLIN Database
PNP - Polyribonucleotide nucleotidyltransferase
UniProt: P50849 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 705 (686)
Sequences: 2511 (1138)
Seq/√Len: 43.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
253_D276_A5.2191.00
537_S540_A4.8051.00
183_K220_E4.6991.00
561_I569_V4.6911.00
355_C450_A4.5461.00
321_G324_Q4.3561.00
23_Q331_E4.0201.00
655_L667_V3.9391.00
460_A501_K3.8641.00
629_K672_E3.6131.00
323_D529_K3.5761.00
351_A432_V3.3391.00
627_L674_L3.2251.00
627_L672_E3.1641.00
247_K304_N3.1541.00
43_S115_S3.1291.00
161_F203_E3.0981.00
156_R174_D3.0281.00
333_G453_D2.8831.00
328_L537_S2.7881.00
480_T530_G2.7861.00
500_E539_L2.7761.00
312_E475_H2.7671.00
43_S133_G2.7611.00
211_E214_R2.7531.00
166_T169_Q2.6891.00
500_E536_N2.6551.00
465_I480_T2.6061.00
598_I610_K2.6011.00
244_E248_A2.6001.00
9_T16_T2.5711.00
250_A277_V2.5431.00
158_D172_K2.5421.00
572_P575_K2.5371.00
157_I162_I2.5131.00
254_L270_I2.4711.00
416_I426_V2.4331.00
557_L606_N2.3741.00
544_E547_K2.3681.00
262_E265_A2.3681.00
156_R200_I2.3551.00
650_V655_L2.3341.00
412_L447_S2.3261.00
631_K647_D2.3251.00
139_S223_V2.3041.00
375_K409_E2.2941.00
325_I480_T2.2881.00
621_E624_Q2.2741.00
611_K615_D2.2331.00
418_S421_D2.2261.00
353_S446_A2.2161.00
579_K583_E2.1791.00
668_K671_D2.1631.00
690_R694_L2.1551.00
525_Q529_K2.1531.00
114_I394_M2.1511.00
603_E607_Q2.1431.00
560_T595_T2.1030.99
631_K641_E2.0980.99
17_L36_Y2.0980.99
123_N168_D2.0900.99
26_K434_E2.0810.99
517_R521_E2.0730.99
245_K284_E2.0690.99
217_A221_E2.0460.99
154_V163_I2.0430.99
610_K614_E2.0190.99
559_M610_K1.9970.99
140_V226_V1.9960.99
76_G79_K1.9950.99
179_V208_G1.9810.99
677_V686_V1.9680.99
8_F225_A1.9490.99
330_S541_T1.9470.99
583_E612_I1.9400.99
679_E687_N1.9340.99
19_V34_I1.9270.99
183_K217_A1.9210.99
252_E256_K1.9070.99
40_A336_P1.9030.99
337_R552_Y1.9000.99
453_D546_R1.8980.99
311_T475_H1.8950.99
29_N142_D1.8900.99
528_K532_M1.8900.99
37_G121_D1.8890.99
607_Q610_K1.8810.99
448_T461_P1.8670.99
19_V132_F1.8660.99
620_V677_V1.8510.99
476_Y522_E1.8480.99
448_T539_L1.8440.99
116_I386_F1.8390.99
608_K611_K1.8380.99
275_N279_A1.8380.99
655_L660_V1.8360.99
146_E513_E1.8240.98
160_Q169_Q1.8230.98
415_V458_I1.8210.98
640_V650_V1.8160.98
359_A599_S1.8070.98
249_L280_K1.8040.98
585_G605_G1.7900.98
654_E692_A1.7840.98
34_I133_G1.7770.98
155_G173_S1.7730.98
186_I205_I1.7730.98
197_P200_I1.7650.98
9_T18_T1.7640.98
322_V477_T1.7570.98
461_P539_L1.7550.98
269_A272_E1.7480.98
24_L433_L1.7300.98
411_A505_A1.7260.98
308_R312_E1.7170.98
662_K665_D1.7010.98
460_A500_E1.6820.97
353_S428_L1.6760.97
568_D616_L1.6640.97
268_D272_E1.6600.97
32_V136_L1.6580.97
325_I533_E1.6490.97
650_V667_V1.6440.97
206_M517_R1.6390.97
673_I690_R1.6310.97
156_R161_F1.6270.97
247_K251_E1.6180.97
355_C428_L1.6110.97
132_F215_L1.6090.97
99_I138_L1.6090.97
40_A335_L1.6010.96
272_E276_A1.5940.96
154_V207_F1.5940.96
174_D194_D1.5780.96
354_V431_E1.5760.96
652_I663_V1.5730.96
240_E244_E1.5660.96
392_G395_R1.5660.96
8_F222_I1.5550.96
11_D16_T1.5520.96
635_K664_E1.5500.96
607_Q611_K1.5460.96
19_V136_L1.5430.96
185_A514_G1.5430.96
168_D171_E1.5370.95
618_R624_Q1.5340.95
557_L610_K1.5280.95
35_R38_D1.5250.95
153_T176_N1.5180.95
215_L219_Q1.5130.95
555_K600_S1.5090.95
355_C454_A1.5090.95
598_I613_I1.5090.95
47_A143_I1.5060.95
591_E595_T1.4970.95
385_Q394_M1.4960.95
689_S692_A1.4960.95
539_L543_S1.4950.95
8_F221_E1.4910.95
648_G688_L1.4900.95
657_L693_V1.4900.95
181_G212_I1.4890.95
127_E153_T1.4880.95
330_S537_S1.4780.94
656_A690_R1.4720.94
163_I207_F1.4650.94
471_K512_I1.4620.94
11_D14_G1.4560.94
257_A273_V1.4520.94
559_M598_I1.4480.94
245_K249_L1.4420.94
608_K612_I1.4300.93
329_S343_L1.4280.93
533_E537_S1.4270.93
681_D685_R1.4140.93
242_L297_I1.4110.93
600_S606_N1.4110.93
323_D526_Q1.4100.93
191_A506_L1.4060.93
131_M149_I1.3970.93
47_A231_S1.3950.92
572_P576_Q1.3840.92
415_V462_V1.3820.92
642_I686_V1.3810.92
441_Q444_I1.3790.92
10_I17_L1.3660.92
253_D256_K1.3650.92
142_D231_S1.3640.92
633_I663_V1.3640.92
47_A107_F1.3630.92
136_L222_I1.3620.92
325_I465_I1.3600.91
584_T608_K1.3440.91
641_E647_D1.3420.91
107_F231_S1.3380.91
632_R685_R1.3380.91
576_Q616_L1.3350.91
34_I129_A1.3350.91
379_H447_S1.3320.91
15_R36_Y1.3300.91
199_E521_E1.3200.90
537_S541_T1.3180.90
584_T612_I1.3110.90
115_S130_A1.3090.90
107_F111_V1.3070.90
379_H443_S1.3050.90
600_S605_G1.3010.90
175_I196_V1.2980.89
105_D303_K1.2970.89
7_V18_T1.2970.89
625_L693_V1.2920.89
363_V374_S1.2850.89
278_V295_K1.2850.89
338_T354_V1.2840.89
139_S219_Q1.2840.89
197_P503_V1.2730.88
161_F200_I1.2710.88
620_V642_I1.2600.88
352_L433_L1.2590.88
602_D605_G1.2550.88
19_V32_V1.2550.88
596_I613_I1.2440.87
168_D172_K1.2430.87
317_P485_M1.2340.87
61_V95_I1.2290.87
99_I134_S1.2290.87
36_Y129_A1.2290.87
267_E271_N1.2260.87
68_Y429_V1.2190.86
120_V126_S1.2170.86
223_V227_G1.2170.86
632_R669_I1.2160.86
569_V596_I1.2110.86
18_T35_R1.1970.85
314_K475_H1.1960.85
229_E232_E1.1950.85
604_S608_K1.1890.85
660_V665_D1.1890.85
274_K295_K1.1890.85
351_A442_A1.1830.84
452_M458_I1.1820.84
29_N46_T1.1810.84
131_M151_G1.1810.84
536_N540_A1.1790.84
44_T385_Q1.1700.84
377_F447_S1.1670.84
33_M118_M1.1630.83
199_E525_Q1.1610.83
462_V499_T1.1560.83
581_I586_V1.1530.83
106_G235_L1.1510.83
194_D414_P1.1490.83
260_V269_A1.1410.82
525_Q528_K1.1400.82
246_V277_V1.1390.82
243_N247_K1.1380.82
106_G233_I1.1360.82
351_A446_A1.1350.82
72_K79_K1.1300.82
641_E644_S1.1290.82
239_D293_Q1.1290.82
650_V693_V1.1280.82
277_V298_L1.1280.82
307_R491_D1.1280.82
39_T126_S1.1260.81
273_V276_A1.1250.81
604_S607_Q1.1240.81
250_A273_V1.1220.81
64_E88_A1.1200.81
251_E255_L1.1150.81
533_E536_N1.1140.81
47_A111_V1.1080.80
633_I669_I1.1040.80
199_E203_E1.1040.80
444_I497_A1.1020.80
220_E224_A1.1000.80
189_V508_M1.1000.80
174_D200_I1.1000.80
162_I169_Q1.1000.80
569_V572_P1.0980.80
161_F207_F1.0980.80
448_T452_M1.0970.80
57_F111_V1.0970.80
19_V222_I1.0960.80
612_I615_D1.0920.79
467_M478_V1.0910.79
655_L666_V1.0880.79
159_D174_D1.0880.79
255_L259_Q1.0880.79
471_K476_Y1.0870.79
383_F387_S1.0870.79
530_G533_E1.0820.79
611_K614_E1.0820.79
118_M352_L1.0730.78
306_V310_I1.0720.78
201_M503_V1.0710.78
151_G180_A1.0710.78
142_D230_K1.0710.78
642_I677_V1.0700.78
652_I662_K1.0700.78
428_L450_A1.0700.78
386_F433_L1.0700.78
246_V250_A1.0690.78
142_D228_K1.0680.78
254_L305_E1.0670.78
87_K91_A1.0650.78
195_E460_A1.0650.78
430_S446_A1.0600.77
17_L132_F1.0590.77
24_L343_L1.0510.77
458_I461_P1.0510.77
29_N47_A1.0500.77
569_V576_Q1.0480.76
213_K217_A1.0430.76
376_R419_E1.0410.76
565_K619_E1.0360.76
466_A478_V1.0350.76
415_V460_A1.0350.76
249_L281_F1.0320.75
254_L298_L1.0310.75
620_V643_F1.0310.75
638_A667_V1.0300.75
290_T293_Q1.0290.75
21_T136_L1.0290.75
480_T533_E1.0280.75
31_A44_T1.0270.75
12_W17_L1.0240.75
38_D337_R1.0240.75
548_E603_E1.0130.74
580_I612_I1.0080.74
119_S338_T1.0020.73
334_L343_L1.0020.73
19_V218_F1.0020.73
54_L108_R1.0010.73
280_K284_E1.0010.73
643_F646_K1.0000.73
332_V453_D0.9990.73
335_L354_V0.9960.73
358_G362_D0.9910.72
655_L663_V0.9900.72
20_E35_R0.9880.72
360_L363_V0.9880.72
249_L277_V0.9860.72
175_I204_A0.9860.72
398_G401_E0.9840.72
569_V613_I0.9830.72
622_V679_E0.9830.72
434_E439_T0.9820.72
412_L451_M0.9810.72
556_I599_S0.9800.71
30_G45_A0.9790.71
654_E691_K0.9790.71
353_S379_H0.9770.71
33_M40_A0.9750.71
628_G640_V0.9750.71
259_Q309_L0.9740.71
674_L693_V0.9740.71
314_K477_T0.9720.71
40_A338_T0.9710.71
337_R550_S0.9680.71
115_S134_S0.9660.70
311_T477_T0.9630.70
47_A142_D0.9620.70
660_V667_V0.9620.70
382_N429_V0.9610.70
328_L530_G0.9590.70
542_L546_R0.9590.70
245_K248_A0.9550.69
218_F222_I0.9520.69
342_G432_V0.9500.69
363_V425_T0.9500.69
422_F457_P0.9490.69
656_A660_V0.9480.69
449_L453_D0.9460.69
449_L542_L0.9440.69
195_E415_V0.9440.69
305_E308_R0.9440.69
25_A42_L0.9430.68
98_P180_A0.9410.68
238_I243_N0.9410.68
110_E393_P0.9400.68
633_I667_V0.9390.68
62_N89_V0.9390.68
41_V115_S0.9380.68
569_V616_L0.9370.68
253_D273_V0.9340.68
208_G211_E0.9330.68
332_V542_L0.9310.68
258_I305_E0.9300.67
559_M613_I0.9300.67
279_A283_D0.9290.67
115_S133_G0.9270.67
365_I374_S0.9260.67
579_K612_I0.9250.67
586_V605_G0.9250.67
195_E501_K0.9220.67
314_K322_V0.9200.67
210_E213_K0.9160.66
650_V690_R0.9160.66
198_E528_K0.9150.66
300_K303_K0.9140.66
568_D576_Q0.9110.66
237_E240_E0.9100.66
24_L40_A0.9070.65
54_L57_F0.9070.65
192_G410_R0.9050.65
242_L246_V0.9010.65
156_R175_I0.8980.65
274_K298_L0.8960.65
518_E522_E0.8950.64
578_N582_E0.8940.64
240_E243_N0.8930.64
214_R217_A0.8890.64
618_R643_F0.8880.64
332_V541_T0.8850.64
112_Q391_T0.8840.63
580_I586_V0.8830.63
83_R89_V0.8810.63
408_G444_I0.8810.63
628_G688_L0.8800.63
47_A109_N0.8800.63
562_N619_E0.8790.63
66_R431_E0.8790.63
387_S439_T0.8790.63
463_A532_M0.8780.63
375_K406_A0.8770.63
530_G537_S0.8760.63
227_G230_K0.8760.63
657_L694_L0.8750.63
63_Y130_A0.8740.63
145_F148_P0.8720.62
330_S449_L0.8720.62
286_H289_D0.8700.62
157_I172_K0.8700.62
10_I218_F0.8690.62
95_I115_S0.8680.62
28_A46_T0.8680.62
213_K216_I0.8670.62
220_E223_V0.8620.61
559_M596_I0.8600.61
68_Y431_E0.8600.61
660_V663_V0.8520.61
558_T595_T0.8490.60
57_F109_N0.8490.60
217_A220_E0.8450.60
569_V617_V0.8440.60
192_G406_A0.8410.60
45_A133_G0.8410.60
463_A539_L0.8410.60
388_V392_G0.8400.59
428_L447_S0.8390.59
255_L313_E0.8390.59
63_Y88_A0.8390.59
91_A125_S0.8370.59
448_T538_M0.8360.59
256_K269_A0.8340.59
189_V466_A0.8340.59
516_S519_I0.8340.59
332_V546_R0.8320.59
185_A189_V0.8320.59
278_V282_E0.8310.59
243_N297_I0.8280.58
247_K301_L0.8270.58
262_E348_Q0.8270.58
634_E639_F0.8260.58
161_F204_A0.8250.58
283_D286_H0.8240.58
127_E178_V0.8240.58
45_A137_A0.8230.58
328_L533_E0.8230.58
200_I203_E0.8220.58
689_S693_V0.8210.58
658_E661_G0.8190.58
555_K605_G0.8180.57
628_G648_G0.8180.57
677_V680_I0.8160.57
561_I588_I0.8150.57
272_E275_N0.8130.57
630_V667_V0.8130.57
141_S230_K0.8120.57
641_E645_G0.8110.57
279_A282_E0.8100.57
261_H265_A0.8080.56
121_D124_C0.8070.56
594_G598_I0.8060.56
259_Q313_E0.8050.56
580_I609_A0.8040.56
560_T593_D0.8030.56
355_C446_A0.8030.56
209_H213_K0.8020.56
638_A663_V0.8020.56
88_A379_H0.8020.56
206_M521_E0.8010.56
629_K641_E0.8000.56
385_Q396_G0.7980.56
299_S302_V0.7980.56
150_A515_L0.7980.56
245_K281_F0.7970.55
667_V673_I0.7960.55
310_I470_V0.7960.55
12_W215_L0.7950.55
92_S617_V0.7950.55
562_N568_D0.7940.55
21_T226_V0.7930.55
83_R396_G0.7930.55
453_D542_L0.7930.55
632_R687_N0.7920.55
265_A268_D0.7860.54
15_R124_C0.7860.54
239_D290_T0.7840.54
32_V222_I0.7830.54
549_L555_K0.7830.54
257_A270_I0.7830.54
353_S377_F0.7820.54
689_S694_L0.7810.54
38_D551_R0.7810.54
150_A207_F0.7810.54
221_E225_A0.7800.54
15_R169_Q0.7800.54
43_S134_S0.7790.54
46_T112_Q0.7770.54
21_T32_V0.7750.53
572_P596_I0.7750.53
634_E669_I0.7740.53
650_V673_I0.7730.53
128_M132_F0.7730.53
260_V265_A0.7730.53
206_M210_E0.7700.53
276_A279_A0.7700.53
276_A280_K0.7680.53
353_S432_V0.7670.53
45_A143_I0.7660.53
255_L305_E0.7640.52
57_F108_R0.7630.52
640_V655_L0.7620.52
41_V95_I0.7620.52
265_A269_A0.7620.52
636_F649_L0.7610.52
250_A281_F0.7590.52
378_M416_I0.7580.52
416_I451_M0.7580.52
105_D654_E0.7570.52
48_S54_L0.7560.52
62_N92_S0.7540.51
345_T434_E0.7520.51
377_F413_E0.7510.51
177_L196_V0.7510.51
250_A253_D0.7470.51
296_Q299_S0.7460.51
73_I378_M0.7460.51
310_I317_P0.7440.50
365_I372_E0.7430.50
34_I41_V0.7420.50
51_P54_L0.7410.50
458_I683_Q0.7380.50
31_A42_L0.7380.50
654_E678_T0.7370.50
566_I590_I0.7350.50
23_Q33_M0.7350.50
26_K345_T0.7340.49
210_E517_R0.7330.49
135_S148_P0.7330.49
576_Q579_K0.7330.49
360_L425_T0.7320.49
588_I613_I0.7310.49
342_G449_L0.7310.49
44_T114_I0.7300.49
421_D459_K0.7300.49
105_D299_S0.7300.49
422_F456_V0.7290.49
13_A17_L0.7280.49
77_F365_I0.7270.49
522_E526_Q0.7250.49
453_D584_T0.7240.48
309_L313_E0.7240.48
285_E294_V0.7240.48
451_M456_V0.7220.48
636_F639_F0.7220.48
406_A409_E0.7210.48
24_L352_L0.7210.48
111_V231_S0.7200.48
77_F367_D0.7200.48
679_E682_K0.7190.48
64_E114_I0.7180.48
628_G647_D0.7180.48
87_K125_S0.7180.48
244_E247_K0.7170.48
452_M542_L0.7170.48
51_P109_N0.7160.48
118_M431_E0.7140.48
189_V506_L0.7140.48
198_E531_R0.7130.47
11_D15_R0.7130.47
408_G441_Q0.7120.47
241_E244_E0.7120.47
565_K568_D0.7100.47
676_K691_K0.7100.47
328_L536_N0.7090.47
243_N300_K0.7070.47
34_I132_F0.7050.47
448_T458_I0.7030.46
92_S398_G0.7030.46
476_Y518_E0.7010.46
79_K85_S0.7010.46
184_D513_E0.6990.46
27_Q434_E0.6990.46
550_S553_A0.6980.46
21_T222_I0.6980.46
274_K299_S0.6980.46
255_L309_L0.6970.46
478_V522_E0.6970.46
45_A134_S0.6960.46
559_M617_V0.6960.46
636_F647_D0.6950.46
449_L585_G0.6940.46
152_V215_L0.6930.46
78_I86_E0.6930.46
153_T441_Q0.6930.46
476_Y519_I0.6920.45
160_Q232_E0.6910.45
205_I520_L0.6910.45
467_M508_M0.6900.45
250_A254_L0.6900.45
91_A127_E0.6890.45
299_S488_A0.6890.45
428_L458_I0.6840.45
157_I173_S0.6840.45
580_I584_T0.6820.44
114_I385_Q0.6820.44
106_G293_Q0.6820.44
351_A379_H0.6820.44
605_G608_K0.6820.44
625_L676_K0.6820.44
153_T178_V0.6810.44
267_E388_V0.6810.44
510_I519_I0.6800.44
256_K259_Q0.6780.44
663_V666_V0.6780.44
500_E532_M0.6760.44
202_L524_L0.6750.44
152_V163_I0.6750.44
132_F136_L0.6750.44
655_L673_I0.6740.44
160_Q203_E0.6730.44
466_A489_L0.6730.44
628_G652_I0.6730.44
36_Y124_C0.6720.44
561_I566_I0.6710.43
63_Y126_S0.6700.43
112_Q393_P0.6700.43
149_I273_V0.6690.43
136_L219_Q0.6690.43
624_Q646_K0.6690.43
584_T588_I0.6680.43
64_E397_P0.6680.43
586_V600_S0.6670.43
29_N231_S0.6670.43
293_Q297_I0.6660.43
376_R425_T0.6640.43
112_Q394_M0.6630.43
638_A666_V0.6620.43
467_M527_A0.6620.43
248_A252_E0.6620.43
678_T687_N0.6600.42
17_L218_F0.6600.42
212_I216_I0.6590.42
314_K323_D0.6580.42
151_G205_I0.6580.42
614_E618_R0.6580.42
452_M546_R0.6570.42
268_D271_N0.6570.42
353_S448_T0.6560.42
567_R572_P0.6560.42
264_H267_E0.6560.42
84_P396_G0.6560.42
196_V200_I0.6560.42
10_I214_R0.6550.42
391_T395_R0.6550.42
632_R635_K0.6550.42
595_T598_I0.6530.42
378_M425_T0.6530.42
259_Q315_V0.6530.42
602_D607_Q0.6520.42
55_D488_A0.6520.42
467_M526_Q0.6510.42
521_E525_Q0.6500.42
621_E626_Y0.6500.42
12_W132_F0.6480.41
363_V419_E0.6480.41
271_N275_N0.6470.41
111_V143_I0.6470.41
586_V612_I0.6460.41
95_I130_A0.6460.41
325_I537_S0.6460.41
62_N408_G0.6460.41
72_K76_G0.6450.41
195_E499_T0.6440.41
32_V137_A0.6430.41
581_I596_I0.6430.41
128_M178_V0.6420.41
496_V523_A0.6420.41
30_G137_A0.6410.41
411_A504_T0.6410.41
615_D618_R0.6410.41
600_S603_E0.6400.41
280_K386_F0.6390.40
557_L598_I0.6380.40
415_V499_T0.6380.40
625_L674_L0.6380.40
50_E295_K0.6370.40
334_L352_L0.6370.40
152_V181_G0.6360.40
441_Q497_A0.6340.40
41_V128_M0.6340.40
175_I200_I0.6330.40
170_L176_N0.6330.40
616_L620_V0.6330.40
72_K77_F0.6320.40
413_E416_I0.6310.40
385_Q391_T0.6310.40
638_A659_R0.6310.40
149_I180_A0.6300.40
82_G397_P0.6290.40
62_N396_G0.6280.39
605_G609_A0.6280.39
205_I208_G0.6280.39
532_M536_N0.6260.39
556_I597_F0.6260.39
557_L607_Q0.6250.39
109_N231_S0.6250.39
52_K105_D0.6250.39
353_S447_S0.6240.39
23_Q334_L0.6240.39
396_G672_E0.6240.39
30_G140_V0.6230.39
183_K213_K0.6220.39
105_D488_A0.6220.39
638_A665_D0.6210.39
64_E116_I0.6190.39
518_E521_E0.6180.39
516_S520_L0.6180.39
62_N393_P0.6180.39
132_F150_A0.6180.39
674_L690_R0.6180.39
156_R196_V0.6180.39
33_M42_L0.6160.38
656_A666_V0.6160.38
564_D567_R0.6160.38
581_I589_D0.6160.38
297_I301_L0.6160.38
258_I317_P0.6160.38
428_L451_M0.6150.38
204_A208_G0.6150.38
64_E379_H0.6140.38
536_N539_L0.6140.38
632_R677_V0.6140.38
690_R693_V0.6140.38
618_R626_Y0.6140.38
383_F388_V0.6130.38
306_V317_P0.6120.38
62_N398_G0.6120.38
30_G228_K0.6110.38
496_V527_A0.6110.38
17_L124_C0.6100.38
136_L140_V0.6100.38
385_Q392_G0.6090.38
212_I215_L0.6090.38
273_V298_L0.6080.38
615_D643_F0.6080.38
179_V205_I0.6080.38
77_F118_M0.6070.38
145_F219_Q0.6050.37
659_R665_D0.6040.37
633_I636_F0.6030.37
78_I368_G0.6030.37
359_A555_K0.6030.37
397_P402_I0.6020.37
252_E255_L0.6000.37
87_K92_S0.6000.37
647_D677_V0.6000.37
632_R639_F0.6000.37
78_I687_N0.6000.37
642_I647_D0.6000.37
37_G124_C0.5990.37
14_G169_Q0.5980.37
158_D171_E0.5970.37
656_A693_V0.5970.37
142_D227_G0.5950.37
452_M539_L0.5950.37
291_I295_K0.5930.36
317_P483_Q0.5930.36
676_K692_A0.5920.36
110_E526_Q0.5920.36
333_G446_A0.5920.36
159_D200_I0.5920.36
615_D644_S0.5910.36
583_E608_K0.5910.36
73_I76_G0.5890.36
243_N246_V0.5890.36
203_E517_R0.5880.36
342_G446_A0.5870.36
667_V671_D0.5860.36
221_E224_A0.5860.36
201_M204_A0.5860.36
135_S150_A0.5850.36
411_A497_A0.5850.36
70_V122_Q0.5850.36
277_V281_F0.5850.36
333_G546_R0.5850.36
672_E687_N0.5840.36
12_W152_V0.5830.35
29_N44_T0.5830.35
412_L416_I0.5820.35
117_V388_V0.5810.35
329_S537_S0.5810.35
488_A515_L0.5810.35
442_A463_A0.5810.35
189_V467_M0.5790.35
376_R416_I0.5780.35
642_I688_L0.5780.35
510_I516_S0.5770.35
432_V439_T0.5770.35
441_Q555_K0.5770.35
251_E305_E0.5760.35
551_R555_K0.5760.35
270_I560_T0.5760.35
358_G425_T0.5760.35
314_K522_E0.5760.35
238_I300_K0.5760.35
219_Q225_A0.5760.35
222_I225_A0.5760.35
242_L294_V0.5760.35
134_S149_I0.5750.35
545_S549_L0.5730.35
179_V410_R0.5730.35
254_L292_K0.5720.34
140_V143_I0.5720.34
631_K639_F0.5720.34
328_L442_A0.5710.34
49_K271_N0.5710.34
189_V489_L0.5710.34
245_K285_E0.5710.34
27_Q439_T0.5680.34
656_A686_V0.5680.34
136_L218_F0.5670.34
584_T609_A0.5670.34
45_A89_V0.5660.34
297_I300_K0.5650.34
348_Q436_N0.5650.34
678_T689_S0.5640.34
526_Q529_K0.5640.34
254_L273_V0.5630.34
170_L173_S0.5630.34
409_E413_E0.5630.34
116_I431_E0.5620.34
563_P581_I0.5620.34
314_K476_Y0.5620.34
46_T443_S0.5610.34
601_T606_N0.5610.34
42_L116_I0.5600.33
125_S281_F0.5600.33
667_V693_V0.5600.33
324_Q614_E0.5600.33
515_L520_L0.5600.33
152_V212_I0.5600.33
91_A149_I0.5590.33
599_S606_N0.5590.33
569_V588_I0.5590.33
634_E649_L0.5580.33
258_I306_V0.5580.33
379_H432_V0.5580.33
50_E53_P0.5580.33
49_K268_D0.5580.33
301_L305_E0.5570.33
99_I149_I0.5570.33
596_I599_S0.5570.33
204_A439_T0.5560.33
228_K625_L0.5560.33
17_L215_L0.5560.33
278_V291_I0.5550.33
620_V646_K0.5550.33
676_K689_S0.5540.33
38_D550_S0.5540.33
191_A485_M0.5540.33
489_L512_I0.5540.33
633_I652_I0.5530.33
250_A298_L0.5520.33
46_T114_I0.5520.33
638_A652_I0.5520.33
8_F218_F0.5520.33
448_T542_L0.5510.33
67_L369_L0.5510.33
140_V229_E0.5500.33
28_A31_A0.5500.33
247_K250_A0.5500.33
652_I659_R0.5490.33
325_I463_A0.5480.32
68_Y382_N0.5470.32
233_I236_F0.5460.32
580_I608_K0.5450.32
595_T599_S0.5440.32
586_V613_I0.5440.32
24_L33_M0.5440.32
43_S92_S0.5430.32
411_A641_E0.5430.32
156_R203_E0.5420.32
406_A413_E0.5420.32
89_V439_T0.5410.32
530_G557_L0.5390.32
114_I386_F0.5390.32
40_A118_M0.5390.32
179_V189_V0.5390.32
192_G413_E0.5380.32
471_K474_E0.5370.32
626_Y649_L0.5370.32
533_E540_A0.5370.32
630_V638_A0.5370.32
299_S303_K0.5360.31
246_V265_A0.5360.31
207_F211_E0.5340.31
635_K679_E0.5340.31
658_E666_V0.5330.31
466_A526_Q0.5330.31
328_L465_I0.5320.31
446_A449_L0.5320.31
432_V443_S0.5320.31
142_D258_I0.5320.31
607_Q614_E0.5310.31
89_V556_I0.5310.31
428_L454_A0.5310.31
241_E245_K0.5310.31
31_A118_M0.5310.31
46_T116_I0.5300.31
185_A209_H0.5300.31
267_E348_Q0.5300.31
594_G601_T0.5300.31
351_A430_S0.5290.31
25_A44_T0.5280.31
146_E227_G0.5280.31
664_E668_K0.5280.31
251_E301_L0.5280.31
8_F19_V0.5280.31
246_V249_L0.5270.31
246_V281_F0.5260.31
70_V369_L0.5260.31
117_V550_S0.5260.31
266_R483_Q0.5260.31
624_Q642_I0.5260.31
35_R124_C0.5260.31
325_I538_M0.5260.31
277_V280_K0.5240.30
119_S563_P0.5240.30
77_F629_K0.5240.30
282_E294_V0.5240.30
319_G480_T0.5240.30
182_T515_L0.5220.30
361_G589_D0.5220.30
441_Q578_N0.5220.30
654_E687_N0.5220.30
633_I671_D0.5220.30
68_Y354_V0.5220.30
189_V520_L0.5220.30
360_L419_E0.5210.30
244_E256_K0.5210.30
46_T391_T0.5210.30
88_A371_V0.5200.30
306_V489_L0.5200.30
580_I600_S0.5190.30
680_I686_V0.5190.30
342_G379_H0.5190.30
557_L600_S0.5190.30
143_I230_K0.5190.30
35_R40_A0.5180.30
210_E214_R0.5180.30
472_S475_H0.5180.30
281_F285_E0.5180.30
45_A138_L0.5170.30
327_P530_G0.5170.30
198_E532_M0.5160.30
21_T24_L0.5160.30
94_L178_V0.5150.30
559_M614_E0.5150.30
576_Q617_V0.5150.30
291_I294_V0.5150.30
599_S616_L0.5150.30
642_I683_Q0.5150.30
139_S220_E0.5150.30
107_F145_F0.5140.30
377_F450_A0.5140.30
525_Q532_M0.5130.30
604_S611_K0.5130.30
323_D522_E0.5130.30
377_F434_E0.5130.30
132_F218_F0.5130.30
359_A425_T0.5120.30
16_T470_V0.5120.30
526_Q530_G0.5120.30
107_F232_E0.5110.29
195_E504_T0.5110.29
503_V532_M0.5110.29
13_A590_I0.5100.29
52_K62_N0.5100.29
112_Q392_G0.5090.29
556_I610_K0.5090.29
113_V245_K0.5080.29
139_S147_G0.5070.29
594_G599_S0.5070.29
662_K666_V0.5060.29
654_E679_E0.5060.29
358_G538_M0.5060.29
286_H294_V0.5060.29
224_A272_E0.5060.29
60_T110_E0.5060.29
13_A211_E0.5050.29
88_A687_N0.5050.29
409_E443_S0.5040.29
204_A573_S0.5040.29
485_M687_N0.5040.29
281_F286_H0.5040.29
328_L470_V0.5040.29
483_Q489_L0.5040.29
461_P500_E0.5030.29
258_I270_I0.5030.29
317_P578_N0.5020.29
608_K629_K0.5010.29
622_V680_I0.5010.29
86_E245_K0.5010.29
48_S108_R0.5000.29
154_V161_F0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4nbqA 3 0.9631 100 0.295 Contact Map
3cdiA 3 0.7305 100 0.3 Contact Map
1e3pA 3 0.8738 100 0.327 Contact Map
4aidA 3 0.8014 100 0.341 Contact Map
3u1kA 3 0.8624 100 0.41 Contact Map
3gmeA 3 0.6823 100 0.44 Contact Map
2nn6A 1 0.383 100 0.799 Contact Map
2nn6B 1 0.3291 100 0.83 Contact Map
2je6B 2 0.3277 100 0.833 Contact Map
2po1A 1 0.3305 100 0.834 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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