CBP1 - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

CBP1 - Carboxypeptidase 1

UniProt:	P50848	Sequences: MEIHTYEKEFFDLLKRISHYSEAVALMHWDSRTGAPKNGSEDRAESIGQLSTDIFNIQTSDRMKELIDVLYERFDDLSEDTKKAVELAKKEYEENKKIPEAEYKEYVILCSKAETAWEEAKGKSDFSLFSPYLEQLIEFNKRFITYWGYQEHPYDALLDLFEPGVTVKVLDQLFAELKEAIIPLVKQVTASGNKPDTSFITKAFPKEKQKELSLYFLQELGYDFDGGRLDETVHPFATTLNRGDVRVTTRYDEKDFRTAIFGTIHECGHAIYEQNIDEALSGTNLSDGASMGIHESQSLFYENFIGRNKHFWTPYYKKIQEASPVQFKDISLDDFVRAINESKPSFIRVEADELTYPLHIIIRYEIEKAIFSNEVSVEDLPSLWNQKYQDYLGITPQTDAEGILQDVHWAGGDFGYFPSYALGYMYAAQLKQKMLEDLPEFDALLERGEFHPIKQWLTEKVHIHGKRKKPLDIIKDATGEELNVRYLIDYLSNKYSNLYLL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	501 (486)
Sequences:	1217 (893)
Seq/√Len:	40.5

BACSU - CBP1
HALSA - Q9HMB7
SULSO - Q97UB3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
389_Q	395_T	4.780	1.00
362_I	388_Y	4.079	1.00
171_D	364_Y	4.023	1.00
480_E	483_N	3.969	1.00
375_V	383_L	3.899	1.00
366_I	383_L	3.459	1.00
313_T	446_E	3.387	1.00
397_Q	401_E	3.317	1.00
180_A	492_S	3.278	1.00
134_E	378_E	3.104	1.00
71_Y	89_K	3.042	1.00
468_K	476_D	3.038	1.00
38_N	226_G	2.982	1.00
105_E	135_Q	2.895	1.00
386_Q	395_T	2.884	1.00
180_A	488_I	2.850	1.00
480_E	486_Y	2.820	1.00
83_K	86_E	2.778	1.00
130_S	377_V	2.707	1.00
130_S	378_E	2.701	1.00
220_L	267_C	2.660	1.00
78_S	81_T	2.443	1.00
483_N	486_Y	2.412	1.00
382_S	386_Q	2.408	1.00
309_K	333_D	2.406	1.00
215_Y	318_K	2.396	1.00
152_H	372_S	2.275	1.00
430_L	461_V	2.273	1.00
121_K	250_R	2.264	1.00
434_M	453_I	2.252	1.00
432_Q	486_Y	2.210	1.00
425_M	482_L	2.209	1.00
475_K	481_E	2.207	1.00
222_Y	227_G	2.183	0.99
398_T	401_E	2.158	0.99
386_Q	390_D	2.134	0.99
387_K	391_Y	2.122	0.99
176_E	485_R	2.098	0.99
64_K	92_Y	2.071	0.99
380_L	403_I	2.069	0.99
331_S	334_D	2.065	0.99
210_K	214_L	2.063	0.99
124_S	398_T	2.051	0.99
291_M	419_S	2.048	0.99
119_E	123_K	2.047	0.99
299_L	424_Y	2.024	0.99
178_K	365_E	2.023	0.99
129_F	410_A	1.996	0.99
430_L	474_I	1.979	0.99
303_N	307_R	1.975	0.99
41_E	112_K	1.969	0.99
490_Y	494_K	1.955	0.99
438_L	444_L	1.951	0.99
435_L	442_D	1.936	0.99
310_H	442_D	1.921	0.99
365_E	387_K	1.915	0.99
357_P	424_Y	1.904	0.99
171_D	368_K	1.896	0.98
369_A	374_E	1.889	0.98
19_H	49_Q	1.866	0.98
187_Q	492_S	1.864	0.98
433_K	436_E	1.863	0.98
437_D	460_K	1.863	0.98
300_F	453_I	1.839	0.98
137_I	370_I	1.807	0.98
102_E	142_R	1.787	0.98
155_D	168_K	1.780	0.98
102_E	146_Y	1.775	0.98
151_E	155_D	1.760	0.98
247_V	270_A	1.759	0.97
38_N	225_D	1.753	0.97
56_N	100_E	1.752	0.97
127_S	130_S	1.743	0.97
7_E	84_A	1.742	0.97
217_L	267_C	1.719	0.97
23_A	27_M	1.719	0.97
432_Q	480_E	1.718	0.97
430_L	477_A	1.715	0.97
432_Q	489_D	1.711	0.97
89_K	93_E	1.696	0.97
213_S	263_T	1.696	0.97
15_K	45_E	1.688	0.97
135_Q	138_E	1.671	0.97
11_F	81_T	1.670	0.97
98_I	103_Y	1.668	0.97
84_A	283_T	1.659	0.96
16_R	57_I	1.636	0.96
461_V	473_I	1.627	0.96
116_A	132_Y	1.624	0.96
169_V	471_L	1.616	0.96
203_A	253_E	1.615	0.96
123_K	128_L	1.611	0.96
17_I	57_I	1.609	0.96
216_F	260_I	1.600	0.96
7_E	81_T	1.596	0.96
262_G	349_V	1.579	0.95
8_K	12_D	1.577	0.95
300_F	434_M	1.556	0.95
141_K	376_S	1.548	0.95
316_Y	332_L	1.546	0.95
440_E	443_A	1.544	0.95
237_A	245_V	1.542	0.95
124_S	399_D	1.525	0.94
277_D	463_I	1.512	0.94
454_K	458_T	1.501	0.94
94_E	160_L	1.500	0.94
425_M	487_L	1.496	0.94
130_S	134_E	1.481	0.93
249_T	263_T	1.480	0.93
138_E	142_R	1.471	0.93
216_F	264_I	1.470	0.93
210_K	231_E	1.447	0.92
24_V	47_I	1.443	0.92
67_I	89_K	1.442	0.92
444_L	452_P	1.433	0.92
207_E	210_K	1.431	0.92
101_A	105_E	1.429	0.92
309_K	336_V	1.427	0.92
316_Y	335_F	1.426	0.92
17_I	54_I	1.424	0.92
365_E	391_Y	1.423	0.92
141_K	371_F	1.418	0.92
206_K	231_E	1.400	0.91
45_E	108_I	1.395	0.91
461_V	477_A	1.386	0.91
133_L	377_V	1.381	0.91
38_N	223_D	1.381	0.91
305_I	453_I	1.366	0.90
299_L	303_N	1.366	0.90
110_C	136_L	1.364	0.90
98_I	143_F	1.363	0.90
137_I	414_F	1.362	0.90
185_V	189_T	1.360	0.90
316_Y	320_Q	1.356	0.90
212_L	319_I	1.347	0.89
162_E	290_S	1.343	0.89
197_T	341_E	1.333	0.89
155_D	167_V	1.331	0.89
124_S	400_A	1.328	0.89
364_Y	368_K	1.311	0.88
134_E	138_E	1.305	0.88
366_I	380_L	1.300	0.88
440_E	444_L	1.296	0.88
9_E	62_R	1.294	0.87
224_F	227_G	1.294	0.87
52_T	104_K	1.289	0.87
37_K	225_D	1.287	0.87
9_E	66_L	1.285	0.87
485_R	489_D	1.282	0.87
208_K	211_E	1.278	0.87
468_K	473_I	1.274	0.87
276_I	288_G	1.270	0.86
464_H	468_K	1.267	0.86
105_E	142_R	1.264	0.86
441_F	453_I	1.264	0.86
267_C	270_A	1.261	0.86
148_G	156_A	1.261	0.86
14_L	88_A	1.259	0.86
449_E	452_P	1.259	0.86
157_L	371_F	1.257	0.86
188_V	354_L	1.257	0.86
106_Y	140_N	1.254	0.86
431_K	435_L	1.247	0.85
219_E	314_P	1.247	0.85
116_A	128_L	1.246	0.85
109_L	132_Y	1.244	0.85
91_E	466_K	1.243	0.85
435_L	439_P	1.240	0.85
112_K	135_Q	1.238	0.85
370_I	375_V	1.238	0.85
387_K	390_D	1.237	0.85
178_K	361_I	1.234	0.85
208_K	322_A	1.230	0.85
219_E	315_Y	1.222	0.84
376_S	379_D	1.222	0.84
389_Q	396_P	1.207	0.84
289_A	470_P	1.203	0.83
125_D	128_L	1.197	0.83
13_L	66_L	1.194	0.83
299_L	357_P	1.193	0.83
126_F	399_D	1.191	0.83
439_P	444_L	1.189	0.83
55_F	103_Y	1.186	0.82
433_K	477_A	1.184	0.82
385_N	399_D	1.184	0.82
388_Y	392_L	1.174	0.82
218_Q	224_F	1.172	0.82
145_T	149_Y	1.172	0.82
426_Y	474_I	1.172	0.82
32_R	114_E	1.170	0.82
93_E	97_K	1.169	0.81
104_K	108_I	1.168	0.81
176_E	484_V	1.162	0.81
261_F	339_I	1.157	0.81
488_I	492_S	1.156	0.81
186_K	190_A	1.152	0.81
232_T	237_A	1.149	0.80
215_Y	322_A	1.147	0.80
220_L	450_F	1.136	0.80
205_P	253_E	1.134	0.79
433_K	437_D	1.133	0.79
204_F	323_S	1.130	0.79
86_E	469_K	1.129	0.79
300_F	431_K	1.123	0.79
169_V	172_Q	1.121	0.79
458_T	462_H	1.113	0.78
425_M	491_L	1.113	0.78
90_K	159_D	1.110	0.78
178_K	391_Y	1.109	0.78
62_R	65_E	1.097	0.77
472_D	476_D	1.088	0.77
226_G	243_G	1.086	0.76
487_L	491_L	1.076	0.76
210_K	251_Y	1.072	0.75
245_V	274_Q	1.070	0.75
44_A	111_S	1.067	0.75
386_Q	389_Q	1.066	0.75
37_K	119_E	1.064	0.75
181_I	185_V	1.058	0.74
13_L	60_S	1.052	0.74
25_A	239_T	1.050	0.74
252_D	258_T	1.045	0.74
301_Y	305_I	1.045	0.74
162_E	292_G	1.043	0.73
13_L	62_R	1.040	0.73
250_R	349_V	1.040	0.73
262_G	299_L	1.040	0.73
357_P	421_A	1.039	0.73
396_P	401_E	1.036	0.73
340_N	494_K	1.032	0.73
16_R	53_D	1.030	0.72
145_T	153_P	1.028	0.72
469_K	472_D	1.023	0.72
110_C	410_A	1.020	0.72
267_C	271_I	1.019	0.72
460_K	463_I	1.017	0.72
381_P	399_D	1.016	0.71
371_F	414_F	1.014	0.71
312_W	315_Y	1.013	0.71
26_L	240_L	1.008	0.71
103_Y	107_V	1.007	0.71
149_Y	152_H	1.005	0.71
118_E	407_V	1.005	0.71
431_K	434_M	1.004	0.71
464_H	467_R	0.994	0.70
106_Y	143_F	0.991	0.70
67_I	92_Y	0.986	0.69
68_D	89_K	0.983	0.69
161_F	413_D	0.982	0.69
80_D	467_R	0.981	0.69
346_F	394_I	0.977	0.68
243_G	278_E	0.976	0.68
48_G	108_I	0.972	0.68
124_S	401_E	0.970	0.68
444_L	449_E	0.968	0.68
346_F	401_E	0.967	0.68
275_N	458_T	0.965	0.67
31_S	40_S	0.963	0.67
29_W	230_D	0.962	0.67
227_G	274_Q	0.960	0.67
220_L	264_I	0.957	0.67
151_E	168_K	0.957	0.67
102_E	139_F	0.952	0.66
126_F	130_S	0.950	0.66
180_A	184_L	0.950	0.66
27_M	46_S	0.946	0.66
121_K	401_E	0.946	0.66
276_I	286_S	0.945	0.66
206_K	253_E	0.944	0.66
83_K	87_L	0.942	0.66
136_L	414_F	0.937	0.65
272_Y	473_I	0.937	0.65
183_P	187_Q	0.937	0.65
10_F	63_M	0.936	0.65
40_S	44_A	0.934	0.65
464_H	476_D	0.933	0.65
383_L	387_K	0.932	0.65
220_L	301_Y	0.931	0.65
332_L	335_F	0.927	0.64
29_W	228_R	0.919	0.64
64_K	68_D	0.918	0.64
316_Y	331_S	0.917	0.63
143_F	147_W	0.917	0.63
231_E	251_Y	0.915	0.63
361_I	365_E	0.914	0.63
119_E	128_L	0.913	0.63
161_F	418_P	0.912	0.63
126_F	404_L	0.912	0.63
370_I	403_I	0.910	0.63
489_D	493_N	0.907	0.63
202_K	329_D	0.907	0.63
443_A	446_E	0.904	0.62
67_I	88_A	0.894	0.61
134_E	377_V	0.893	0.61
434_M	441_F	0.892	0.61
385_N	395_T	0.891	0.61
289_A	466_K	0.890	0.61
271_I	454_K	0.889	0.61
178_K	387_K	0.887	0.61
369_A	387_K	0.886	0.61
166_T	169_V	0.885	0.61
233_V	407_V	0.885	0.61
92_Y	96_K	0.885	0.61
149_Y	156_A	0.885	0.61
264_I	306_G	0.883	0.60
63_M	92_Y	0.879	0.60
211_E	322_A	0.878	0.60
317_K	320_Q	0.878	0.60
212_L	260_I	0.876	0.60
20_Y	53_D	0.875	0.60
251_Y	259_A	0.875	0.60
445_L	450_F	0.874	0.60
184_L	344_P	0.873	0.60
43_R	228_R	0.872	0.60
471_L	482_L	0.872	0.60
43_R	230_D	0.869	0.59
188_V	191_S	0.865	0.59
22_E	46_S	0.862	0.59
305_I	445_L	0.861	0.59
144_I	156_A	0.856	0.58
444_L	453_I	0.855	0.58
301_Y	454_K	0.855	0.58
152_H	155_D	0.854	0.58
161_F	419_S	0.854	0.58
473_I	476_D	0.854	0.58
113_A	136_L	0.853	0.58
114_E	118_E	0.853	0.58
256_F	319_I	0.849	0.57
205_P	208_K	0.848	0.57
87_L	466_K	0.848	0.57
124_S	128_L	0.847	0.57
55_F	95_N	0.845	0.57
455_Q	459_E	0.845	0.57
63_M	66_L	0.841	0.57
162_E	419_S	0.837	0.56
324_P	328_K	0.837	0.56
154_Y	418_P	0.837	0.56
105_E	109_L	0.836	0.56
112_K	132_Y	0.836	0.56
222_Y	247_V	0.835	0.56
435_L	493_N	0.834	0.56
237_A	262_G	0.833	0.56
441_F	444_L	0.830	0.56
134_E	376_S	0.829	0.56
431_K	442_D	0.826	0.55
121_K	233_V	0.825	0.55
369_A	375_V	0.824	0.55
32_R	118_E	0.824	0.55
198_S	334_D	0.822	0.55
305_I	434_M	0.820	0.55
170_L	290_S	0.816	0.54
432_Q	483_N	0.814	0.54
471_L	481_E	0.814	0.54
172_Q	176_E	0.812	0.54
243_G	281_S	0.812	0.54
239_T	242_R	0.811	0.54
70_L	85_V	0.811	0.54
144_I	153_P	0.808	0.54
148_G	151_E	0.808	0.54
173_L	425_M	0.808	0.54
486_Y	489_D	0.808	0.54
53_D	56_N	0.807	0.54
178_K	182_I	0.807	0.54
26_L	39_G	0.807	0.54
320_Q	328_K	0.807	0.54
374_E	382_S	0.806	0.54
186_K	189_T	0.806	0.54
214_L	224_F	0.802	0.53
61_D	65_E	0.800	0.53
106_Y	139_F	0.799	0.53
154_Y	158_L	0.799	0.53
212_L	312_W	0.799	0.53
109_L	135_Q	0.796	0.53
77_L	81_T	0.795	0.53
318_K	321_E	0.795	0.53
80_D	285_L	0.795	0.53
318_K	322_A	0.792	0.52
273_E	288_G	0.792	0.52
314_P	448_G	0.790	0.52
388_Y	394_I	0.790	0.52
459_E	463_I	0.784	0.52
189_T	344_P	0.782	0.51
277_D	288_G	0.780	0.51
31_S	47_I	0.778	0.51
304_F	427_A	0.777	0.51
482_L	487_L	0.776	0.51
127_S	131_P	0.775	0.51
472_D	475_K	0.773	0.50
90_K	163_P	0.773	0.50
55_F	59_T	0.771	0.50
7_E	11_F	0.771	0.50
369_A	383_L	0.770	0.50
113_A	410_A	0.770	0.50
52_T	100_E	0.766	0.50
223_D	274_Q	0.764	0.50
120_A	404_L	0.756	0.49
146_Y	404_L	0.755	0.49
309_K	313_T	0.755	0.49
431_K	453_I	0.754	0.49
226_G	274_Q	0.754	0.49
222_Y	270_A	0.749	0.48
277_D	280_L	0.748	0.48
215_Y	321_E	0.745	0.48
40_S	115_T	0.745	0.48
293_I	426_Y	0.743	0.48
106_Y	146_Y	0.742	0.48
102_E	106_Y	0.742	0.48
303_N	424_Y	0.741	0.48
432_Q	436_E	0.740	0.47
242_R	281_S	0.737	0.47
165_V	169_V	0.736	0.47
237_A	487_L	0.736	0.47
216_F	220_L	0.735	0.47
196_D	199_F	0.735	0.47
137_I	375_V	0.735	0.47
167_V	368_K	0.733	0.47
299_L	323_S	0.729	0.46
109_L	139_F	0.727	0.46
161_F	360_I	0.726	0.46
190_A	193_N	0.726	0.46
346_F	388_Y	0.724	0.46
20_Y	54_I	0.721	0.46
64_K	96_K	0.721	0.46
17_I	58_Q	0.720	0.46
13_L	57_I	0.720	0.46
176_E	488_I	0.720	0.46
84_A	284_N	0.718	0.45
204_F	326_Q	0.717	0.45
196_D	334_D	0.717	0.45
65_E	69_V	0.716	0.45
182_I	358_L	0.715	0.45
291_M	411_G	0.715	0.45
229_L	263_T	0.713	0.45
137_I	376_S	0.712	0.45
129_F	350_E	0.711	0.45
340_N	490_Y	0.711	0.45
232_T	248_T	0.709	0.45
10_F	88_A	0.708	0.45
206_K	210_K	0.708	0.45
250_R	262_G	0.707	0.44
444_L	447_R	0.706	0.44
184_L	491_L	0.706	0.44
165_V	170_L	0.706	0.44
199_F	330_I	0.704	0.44
258_T	349_V	0.702	0.44
312_W	335_F	0.701	0.44
280_L	283_T	0.701	0.44
108_I	112_K	0.699	0.44
199_F	338_A	0.698	0.44
443_A	447_R	0.696	0.43
173_L	484_V	0.696	0.43
334_D	337_R	0.696	0.43
130_S	170_L	0.696	0.43
34_G	230_D	0.695	0.43
261_F	312_W	0.695	0.43
454_K	462_H	0.695	0.43
431_K	441_F	0.694	0.43
140_N	371_F	0.692	0.43
118_E	233_V	0.691	0.43
281_S	286_S	0.690	0.43
110_C	411_G	0.688	0.43
345_S	355_T	0.686	0.43
180_A	183_P	0.686	0.43
248_T	296_S	0.685	0.42
137_I	377_V	0.685	0.42
435_L	440_E	0.683	0.42
438_L	441_F	0.682	0.42
113_A	411_G	0.681	0.42
28_H	32_R	0.679	0.42
256_F	323_S	0.677	0.42
25_A	238_T	0.677	0.42
438_L	452_P	0.675	0.42
212_L	216_F	0.673	0.41
120_A	126_F	0.671	0.41
102_E	109_L	0.671	0.41
20_Y	35_A	0.671	0.41
452_P	455_Q	0.670	0.41
425_M	486_Y	0.668	0.41
141_K	156_A	0.668	0.41
222_Y	360_I	0.666	0.41
126_F	376_S	0.666	0.41
161_F	416_Y	0.666	0.41
172_Q	175_A	0.661	0.40
449_E	455_Q	0.661	0.40
144_I	371_F	0.661	0.40
184_L	492_S	0.659	0.40
178_K	264_I	0.657	0.40
273_E	294_H	0.657	0.40
110_C	113_A	0.655	0.40
277_D	286_S	0.651	0.39
357_P	427_A	0.648	0.39
416_Y	422_L	0.648	0.39
272_Y	290_S	0.646	0.39
150_Q	155_D	0.646	0.39
416_Y	419_S	0.645	0.39
262_G	424_Y	0.645	0.39
207_E	211_E	0.645	0.39
212_L	255_D	0.645	0.39
77_L	82_K	0.645	0.39
269_H	294_H	0.644	0.39
44_A	103_Y	0.644	0.39
147_W	156_A	0.644	0.39
140_N	143_F	0.644	0.39
25_A	240_L	0.643	0.39
354_L	487_L	0.642	0.39
173_L	421_A	0.641	0.39
211_E	463_I	0.641	0.39
224_F	274_Q	0.640	0.38
127_S	399_D	0.639	0.38
28_H	114_E	0.639	0.38
100_E	104_K	0.639	0.38
455_Q	458_T	0.638	0.38
229_L	262_G	0.637	0.38
395_T	398_T	0.636	0.38
28_H	238_T	0.636	0.38
7_E	427_A	0.635	0.38
178_K	263_T	0.635	0.38
75_D	82_K	0.633	0.38
9_E	13_L	0.631	0.38
353_E	494_K	0.630	0.38
303_N	494_K	0.630	0.38
114_E	411_G	0.629	0.37
327_F	330_I	0.628	0.37
443_A	493_N	0.628	0.37
26_L	239_T	0.627	0.37
177_L	425_M	0.627	0.37
173_L	482_L	0.626	0.37
114_E	407_V	0.623	0.37
195_P	341_E	0.622	0.37
187_Q	190_A	0.621	0.37
187_Q	496_S	0.621	0.37
14_L	58_Q	0.621	0.37
323_S	424_Y	0.620	0.37
156_A	371_F	0.618	0.37
370_I	380_L	0.618	0.37
44_A	112_K	0.617	0.36
204_F	327_F	0.616	0.36
55_F	144_I	0.616	0.36
102_E	143_F	0.616	0.36
126_F	403_I	0.615	0.36
191_S	194_K	0.613	0.36
97_K	147_W	0.611	0.36
33_T	361_I	0.611	0.36
375_V	403_I	0.609	0.36
291_M	416_Y	0.609	0.36
54_I	263_T	0.609	0.36
147_W	160_L	0.609	0.36
17_I	63_M	0.607	0.36
21_S	54_I	0.607	0.36
300_F	419_S	0.607	0.36
440_E	449_E	0.606	0.36
366_I	369_A	0.606	0.36
44_A	130_S	0.605	0.35
10_F	14_L	0.605	0.35
185_V	342_S	0.604	0.35
470_P	474_I	0.604	0.35
312_W	339_I	0.603	0.35
131_P	134_E	0.602	0.35
312_W	319_I	0.602	0.35
103_Y	139_F	0.602	0.35
80_D	280_L	0.601	0.35
90_K	108_I	0.601	0.35
174_F	421_A	0.599	0.35
217_L	247_V	0.598	0.35
39_G	242_R	0.598	0.35
248_T	298_S	0.597	0.35
362_I	392_L	0.597	0.35
60_S	64_K	0.597	0.35
465_G	473_I	0.597	0.35
49_Q	388_Y	0.593	0.34
107_V	147_W	0.592	0.34
158_L	171_D	0.592	0.34
35_A	43_R	0.591	0.34
312_W	332_L	0.587	0.34
425_M	484_V	0.586	0.34
374_E	386_Q	0.586	0.34
106_Y	109_L	0.585	0.34
13_L	63_M	0.583	0.34
158_L	416_Y	0.583	0.34
293_I	470_P	0.582	0.34
70_L	77_L	0.582	0.34
320_Q	436_E	0.582	0.34
310_H	446_E	0.581	0.33
175_A	178_K	0.580	0.33
170_L	173_L	0.579	0.33
39_G	276_I	0.579	0.33
29_W	227_G	0.579	0.33
258_T	350_E	0.577	0.33
140_N	160_L	0.577	0.33
379_D	382_S	0.576	0.33
366_I	370_I	0.575	0.33
315_Y	319_I	0.575	0.33
303_N	357_P	0.575	0.33
123_K	127_S	0.575	0.33
10_F	70_L	0.573	0.33
145_T	148_G	0.573	0.33
23_A	50_L	0.573	0.33
184_L	488_I	0.572	0.33
25_A	39_G	0.571	0.33
14_L	284_N	0.570	0.33
54_I	58_Q	0.570	0.33
188_V	342_S	0.570	0.33
237_A	270_A	0.569	0.32
301_Y	445_L	0.569	0.32
18_S	21_S	0.569	0.32
67_I	85_V	0.569	0.32
348_R	356_Y	0.569	0.32
233_V	250_R	0.568	0.32
269_H	423_G	0.566	0.32
285_L	467_R	0.566	0.32
378_E	496_S	0.566	0.32
137_I	403_I	0.565	0.32
441_F	445_L	0.564	0.32
435_L	460_K	0.564	0.32
373_N	421_A	0.564	0.32
304_F	424_Y	0.563	0.32
223_D	227_G	0.563	0.32
445_L	453_I	0.563	0.32
170_L	175_A	0.563	0.32
242_R	286_S	0.562	0.32
214_L	218_Q	0.561	0.32
357_P	487_L	0.561	0.32
245_V	270_A	0.560	0.32
127_S	373_N	0.559	0.32
58_Q	88_A	0.558	0.32
450_F	453_I	0.558	0.32
389_Q	447_R	0.558	0.32
236_F	294_H	0.557	0.31
222_Y	274_Q	0.557	0.31
148_G	153_P	0.555	0.31
200_I	338_A	0.555	0.31
407_V	410_A	0.555	0.31
220_L	477_A	0.553	0.31
196_D	341_E	0.552	0.31
121_K	231_E	0.551	0.31
94_E	159_D	0.550	0.31
63_M	88_A	0.550	0.31
266_E	269_H	0.549	0.31
14_L	84_A	0.549	0.31
62_R	66_L	0.549	0.31
297_Q	457_L	0.549	0.31
202_K	326_Q	0.548	0.31
266_E	294_H	0.547	0.31
22_E	240_L	0.547	0.31
30_D	246_R	0.546	0.31
312_W	316_Y	0.546	0.31
47_I	96_K	0.545	0.31
447_R	451_H	0.545	0.31
129_F	161_F	0.545	0.31
158_L	364_Y	0.544	0.30
162_E	426_Y	0.541	0.30
79_E	82_K	0.541	0.30
338_A	404_L	0.540	0.30
64_K	67_I	0.539	0.30
120_A	132_Y	0.538	0.30
179_E	183_P	0.538	0.30
453_I	461_V	0.538	0.30
158_L	418_P	0.537	0.30
162_E	470_P	0.537	0.30
152_H	368_K	0.536	0.30
13_L	17_I	0.536	0.30
220_L	271_I	0.536	0.30
164_G	469_K	0.534	0.30
369_A	373_N	0.534	0.30
315_Y	450_F	0.533	0.30
217_L	396_P	0.533	0.30
353_E	490_Y	0.533	0.30
141_K	369_A	0.532	0.30
90_K	138_E	0.530	0.29
312_W	461_V	0.530	0.29
305_I	451_H	0.530	0.29
283_T	299_L	0.529	0.29
342_S	495_Y	0.529	0.29
175_A	179_E	0.527	0.29
381_P	388_Y	0.526	0.29
416_Y	421_A	0.526	0.29
118_E	121_K	0.525	0.29
137_I	141_K	0.524	0.29
430_L	457_L	0.524	0.29
183_P	186_K	0.524	0.29
269_H	298_S	0.523	0.29
126_F	385_N	0.522	0.29
313_T	332_L	0.522	0.29
161_F	291_M	0.521	0.29
182_I	185_V	0.521	0.29
121_K	267_C	0.521	0.29
429_Q	486_Y	0.521	0.29
162_E	418_P	0.520	0.29
293_I	474_I	0.520	0.29
187_Q	382_S	0.519	0.29
32_R	237_A	0.519	0.29
215_Y	218_Q	0.519	0.29
239_T	427_A	0.518	0.28
94_E	147_W	0.517	0.28
109_L	136_L	0.516	0.28
142_R	145_T	0.516	0.28
168_K	172_Q	0.515	0.28
170_L	292_G	0.514	0.28
80_D	84_A	0.514	0.28
63_M	67_I	0.513	0.28
32_R	232_T	0.513	0.28
278_E	281_S	0.512	0.28
299_L	307_R	0.512	0.28
114_E	132_Y	0.510	0.28
218_Q	225_D	0.509	0.28
263_T	267_C	0.508	0.28
178_K	390_D	0.508	0.28
408_H	423_G	0.508	0.28
370_I	373_N	0.507	0.28
186_K	483_N	0.507	0.28
61_D	96_K	0.506	0.28
39_G	226_G	0.506	0.28
9_E	12_D	0.506	0.28
74_F	82_K	0.504	0.27
44_A	170_L	0.504	0.27
308_N	445_L	0.504	0.27
84_A	285_L	0.503	0.27
142_R	459_E	0.503	0.27
266_E	298_S	0.502	0.27
23_A	46_S	0.502	0.27
120_A	399_D	0.502	0.27
434_M	438_L	0.502	0.27
203_A	254_K	0.502	0.27
236_F	248_T	0.502	0.27
327_F	335_F	0.501	0.27
465_G	469_K	0.501	0.27
158_L	360_I	0.500	0.27
75_D	207_E	0.500	0.27
74_F	86_E	0.500	0.27

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3hoaA	2	0.994	100	0.256	Contact Map
3dwcA	3	0.988	100	0.272	Contact Map
3hq2A	2	0.992	100	0.369	Contact Map
1ka2A	2	0.986	100	0.389	Contact Map
4ca7A	1	0.9421	100	0.662	Contact Map
4ca6A	1	0.9361	100	0.671	Contact Map
4c2oA	1	0.9381	100	0.68	Contact Map
1r42A	1	0.9441	100	0.688	Contact Map
3ahnA	1	0.8922	100	0.774	Contact Map
3ce2A	1	0.8942	100	0.778	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0136 seconds.