KDGR - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

KDGR - HTH-type transcriptional regulator KdgR

UniProt:	P50844	Sequences: MKKKTTGHTTIKDVAECAGVSKSTVSRYINGKIDAISPEKVKNIKKAIAELNYRPSKMAQGLKIKKSKLIGFVVADITNPFSVAAFRGVEEVCDQYGYSIMVCNTDNSPEKEREMLLKLEAHSVEGLILNATGENKDVLRAFAEQQIPTILIDRKLPDLKLDTVTTDNRWITKEILQKVYSKGYTDVALFTEPISSISPRAERAAVYQEMASVQNVNGLVRLHEIDVKDKEQLKAELRSFHKEMPEQKKAILALNGLIMLKIISCMEELGLRIPQDIGIAGFDDTEWYKLIGPGITTIAQPSHDMGRTAMERVLKRIEGDKGAPQTIELEAKVIMRKSL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	339 (324)
Sequences:	34647 (25425)
Seq/√Len:	1412.5

ECOLI - CYTR GALS GALR GNTR PURR IDNR MALI RBSR ASCG CRA LACI YCJW EBGR TRER TORT ALSB YTFQ RBSB XYLF YPHF LSRB ARAF DGAL XYLR
BACSU - KDGR CCPA NTDR RBSR DEGA YKVZ MSMR GANR EXUR ARAR YVDE CCPB RBSB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
169_R	209_E	3.336	1.00
184_Y	249_K	3.222	1.00
17_C	50_E	3.089	1.00
272_R	275_Q	3.070	1.00
175_I	280_A	2.648	1.00
204_A	208_Q	2.570	1.00
184_Y	278_G	2.569	1.00
126_G	313_V	2.540	1.00
284_D	299_A	2.470	1.00
173_K	213_V	2.331	1.00
162_D	316_R	2.311	1.00
38_P	42_K	2.270	1.00
46_K	50_E	2.209	1.00
234_K	268_E	2.208	1.00
42_K	46_K	2.168	1.00
92_V	95_Q	2.142	1.00
238_R	269_L	2.125	1.00
92_V	311_E	2.124	1.00
180_Y	214_Q	2.045	1.00
308_T	311_E	2.027	1.00
170_W	174_E	2.016	1.00
173_K	209_E	2.001	1.00
238_R	265_C	1.993	1.00
173_K	210_M	1.992	1.00
177_Q	210_M	1.992	1.00
28_Y	44_I	1.978	1.00
93_C	310_M	1.952	1.00
41_V	45_K	1.913	1.00
177_Q	181_S	1.886	1.00
29_I	48_I	1.884	1.00
169_R	205_A	1.883	1.00
172_T	176_L	1.868	1.00
171_I	282_F	1.858	1.00
88_G	306_G	1.850	1.00
12_K	22_K	1.846	1.00
32_K	35_A	1.844	1.00
266_M	277_I	1.824	1.00
92_V	307_R	1.812	1.00
233_L	261_K	1.810	1.00
299_A	332_K	1.791	1.00
242_K	269_L	1.790	1.00
172_T	252_L	1.789	1.00
179_V	250_A	1.786	1.00
176_L	207_Y	1.783	1.00
177_Q	214_Q	1.753	1.00
315_K	320_D	1.740	1.00
91_E	303_H	1.720	1.00
17_C	47_A	1.715	1.00
18_A	47_A	1.701	1.00
294_G	337_K	1.695	1.00
173_K	177_Q	1.692	1.00
308_T	327_I	1.675	1.00
301_P	304_D	1.666	1.00
234_K	265_C	1.653	1.00
237_L	262_I	1.637	1.00
71_G	124_V	1.632	1.00
189_L	254_L	1.627	1.00
188_A	248_K	1.620	1.00
174_E	331_A	1.619	1.00
88_G	303_H	1.619	1.00
253_A	262_I	1.613	1.00
271_L	276_D	1.609	1.00
178_K	182_K	1.588	1.00
92_V	96_Y	1.576	1.00
272_R	276_D	1.575	1.00
265_C	269_L	1.556	1.00
152_I	309_A	1.549	1.00
45_K	49_A	1.546	1.00
186_D	219_L	1.530	1.00
267_E	292_G	1.530	1.00
96_Y	314_L	1.499	1.00
304_D	308_T	1.496	1.00
205_A	209_E	1.486	1.00
170_W	173_K	1.485	1.00
186_D	247_Q	1.478	1.00
28_Y	48_I	1.470	1.00
265_C	268_E	1.457	1.00
178_K	181_S	1.457	1.00
167_D	170_W	1.441	1.00
180_Y	210_M	1.440	1.00
224_E	239_S	1.437	1.00
45_K	48_I	1.433	1.00
280_A	296_T	1.430	1.00
14_V	47_A	1.410	1.00
304_D	307_R	1.403	1.00
68_K	125_E	1.395	1.00
202_E	205_A	1.384	1.00
208_Q	212_S	1.366	1.00
178_K	335_M	1.362	1.00
92_V	310_M	1.355	1.00
171_I	331_A	1.340	1.00
284_D	336_R	1.335	1.00
266_M	271_L	1.330	1.00
227_V	232_Q	1.326	1.00
210_M	213_V	1.314	1.00
188_A	240_F	1.301	1.00
12_K	16_E	1.299	1.00
234_K	238_R	1.296	1.00
238_R	268_E	1.296	1.00
176_L	180_Y	1.286	1.00
176_L	206_V	1.282	1.00
238_R	242_K	1.275	1.00
237_L	266_M	1.274	1.00
172_T	206_V	1.271	1.00
244_M	247_Q	1.271	1.00
38_P	41_V	1.269	1.00
176_L	210_M	1.269	1.00
13_D	16_E	1.268	1.00
70_I	93_C	1.267	1.00
186_D	249_K	1.264	1.00
237_L	251_I	1.263	1.00
184_Y	250_A	1.260	1.00
234_K	264_S	1.257	1.00
68_K	98_Y	1.252	1.00
17_C	51_L	1.252	1.00
206_V	210_M	1.246	1.00
311_E	315_K	1.244	1.00
314_L	318_E	1.242	1.00
43_N	47_A	1.237	1.00
140_R	144_E	1.237	1.00
219_L	222_L	1.235	1.00
47_A	50_E	1.233	1.00
37_S	40_K	1.218	1.00
27_R	32_K	1.214	1.00
263_I	279_I	1.206	1.00
177_Q	213_V	1.205	1.00
103_C	115_M	1.200	1.00
103_C	119_L	1.199	1.00
14_V	18_A	1.198	1.00
245_P	248_K	1.196	1.00
11_I	22_K	1.187	1.00
174_E	177_Q	1.186	1.00
72_F	89_V	1.185	1.00
9_T	51_L	1.177	1.00
169_R	173_K	1.175	1.00
93_C	100_I	1.167	1.00
71_G	119_L	1.163	1.00
40_K	43_N	1.163	1.00
128_I	309_A	1.162	1.00
239_S	243_E	1.161	1.00
185_T	249_K	1.155	1.00
89_V	128_I	1.153	1.00
169_R	202_E	1.150	1.00
47_A	51_L	1.147	1.00
89_V	310_M	1.141	1.00
207_Y	211_A	1.122	1.00
211_A	216_V	1.118	1.00
303_H	307_R	1.107	1.00
28_Y	36_I	1.107	1.00
14_V	51_L	1.106	1.00
190_F	262_I	1.101	1.00
231_E	235_A	1.100	1.00
46_K	49_A	1.100	1.00
236_E	239_S	1.099	1.00
187_V	211_A	1.092	1.00
42_K	45_K	1.086	1.00
261_K	265_C	1.082	1.00
210_M	214_Q	1.079	1.00
306_G	310_M	1.075	1.00
96_Y	311_E	1.075	1.00
182_K	335_M	1.072	1.00
31_G	41_V	1.069	1.00
209_E	213_V	1.062	1.00
251_I	262_I	1.060	1.00
189_L	204_A	1.058	1.00
169_R	206_V	1.057	1.00
308_T	312_R	1.055	1.00
175_I	252_L	1.052	1.00
256_G	297_T	1.050	1.00
94_D	111_K	1.048	1.00
244_M	248_K	1.046	1.00
11_I	25_V	1.045	1.00
69_L	101_M	1.042	1.00
117_L	141_A	1.034	1.00
181_S	214_Q	1.034	1.00
72_F	100_I	1.030	1.00
256_G	281_G	1.030	1.00
56_S	62_L	1.025	1.00
180_Y	216_V	1.024	1.00
69_L	99_S	1.021	1.00
90_E	94_D	1.017	1.00
96_Y	318_E	1.009	1.00
307_R	311_E	1.008	1.00
113_R	117_L	1.005	1.00
58_M	61_G	1.002	1.00
229_D	232_Q	1.001	1.00
178_K	296_T	1.000	1.00
98_Y	314_L	0.995	1.00
312_R	327_I	0.993	1.00
205_A	208_Q	0.993	1.00
170_W	330_E	0.979	1.00
253_A	259_M	0.978	1.00
308_T	329_L	0.969	1.00
313_V	317_I	0.966	1.00
253_A	258_I	0.965	1.00
235_A	239_S	0.960	1.00
48_I	51_L	0.960	1.00
18_A	25_V	0.957	1.00
263_I	273_I	0.952	1.00
232_Q	235_A	0.946	1.00
263_I	291_I	0.943	1.00
233_L	237_L	0.943	1.00
185_T	216_V	0.942	1.00
230_K	264_S	0.933	1.00
207_Y	252_L	0.931	1.00
237_L	241_H	0.930	1.00
187_V	250_A	0.930	1.00
175_I	298_I	0.929	1.00
201_A	205_A	0.927	1.00
182_K	278_G	0.927	1.00
111_K	114_E	0.924	1.00
117_L	121_A	0.920	1.00
95_Q	307_R	0.914	1.00
224_E	236_E	0.904	1.00
180_Y	185_T	0.904	1.00
176_L	211_A	0.902	1.00
332_K	335_M	0.899	1.00
31_G	45_K	0.894	1.00
208_Q	218_G	0.893	1.00
166_T	301_P	0.888	1.00
163_T	326_T	0.883	1.00
198_S	202_E	0.883	1.00
55_P	60_Q	0.880	1.00
267_E	294_G	0.876	1.00
56_S	59_A	0.871	1.00
87_R	91_E	0.870	1.00
162_D	312_R	0.869	1.00
128_I	313_V	0.868	1.00
31_G	34_D	0.867	1.00
194_I	225_I	0.866	1.00
301_P	329_L	0.865	1.00
192_E	228_K	0.865	1.00
91_E	307_R	0.862	1.00
170_W	331_A	0.856	1.00
59_A	62_L	0.853	1.00
136_K	140_R	0.852	1.00
167_D	328_E	0.851	1.00
89_V	306_G	0.849	1.00
271_L	277_I	0.849	1.00
312_R	315_K	0.848	1.00
70_I	128_I	0.841	1.00
72_F	86_F	0.841	1.00
301_P	332_K	0.839	1.00
241_H	265_C	0.838	1.00
28_Y	45_K	0.837	1.00
164_V	312_R	0.836	1.00
211_A	218_G	0.835	1.00
85_A	152_I	0.834	1.00
251_I	277_I	0.834	1.00
299_A	334_I	0.833	1.00
188_A	251_I	0.833	1.00
235_A	238_R	0.833	1.00
166_T	331_A	0.831	1.00
165_T	328_E	0.826	1.00
247_Q	271_L	0.823	1.00
167_D	330_E	0.823	1.00
81_F	302_S	0.811	1.00
226_D	258_I	0.808	1.00
266_M	279_I	0.805	1.00
10_T	13_D	0.803	1.00
256_G	284_D	0.802	1.00
67_S	125_E	0.801	1.00
39_E	42_K	0.800	1.00
165_T	326_T	0.798	1.00
168_N	203_R	0.798	1.00
209_E	212_S	0.797	1.00
162_D	325_Q	0.794	1.00
310_M	314_L	0.794	1.00
166_T	300_Q	0.793	1.00
191_T	204_A	0.791	1.00
222_L	243_E	0.791	1.00
281_G	297_T	0.789	1.00
186_D	222_L	0.788	1.00
126_G	317_I	0.787	1.00
20_V	44_I	0.783	1.00
284_D	334_I	0.780	1.00
190_F	253_A	0.780	1.00
27_R	34_D	0.777	1.00
141_A	144_E	0.772	1.00
39_E	43_N	0.770	1.00
218_G	221_R	0.770	1.00
179_V	280_A	0.768	1.00
86_F	90_E	0.766	1.00
69_L	122_H	0.764	1.00
237_L	265_C	0.763	1.00
108_S	111_K	0.763	1.00
84_A	303_H	0.763	1.00
88_G	92_V	0.763	1.00
23_S	27_R	0.761	1.00
66_K	125_E	0.761	1.00
232_Q	236_E	0.757	1.00
57_K	60_Q	0.756	1.00
89_V	100_I	0.754	1.00
284_D	288_Y	0.754	1.00
88_G	307_R	0.752	1.00
249_K	278_G	0.745	1.00
75_A	82_S	0.744	1.00
237_L	240_F	0.742	1.00
189_L	252_L	0.739	1.00
70_I	310_M	0.737	1.00
24_T	27_R	0.736	1.00
91_E	95_Q	0.735	1.00
241_H	269_L	0.731	1.00
174_E	298_I	0.730	1.00
202_E	206_V	0.730	1.00
155_K	326_T	0.728	1.00
114_E	117_L	0.725	1.00
260_L	291_I	0.724	1.00
178_K	333_V	0.722	1.00
120_E	145_Q	0.722	1.00
252_L	280_A	0.721	1.00
266_M	273_I	0.719	1.00
71_G	127_L	0.719	1.00
86_F	102_V	0.716	1.00
243_E	247_Q	0.713	1.00
140_R	143_A	0.712	1.00
87_R	90_E	0.707	1.00
27_R	35_A	0.706	1.00
195_S	201_A	0.701	1.00
101_M	124_V	0.698	1.00
283_D	300_Q	0.698	1.00
264_S	267_E	0.698	1.00
54_R	121_A	0.697	1.00
264_S	294_G	0.695	1.00
315_K	319_G	0.688	1.00
143_A	160_K	0.687	1.00
243_E	248_K	0.685	1.00
151_L	156_L	0.685	1.00
28_Y	41_V	0.684	1.00
42_K	49_A	0.683	1.00
90_E	104_N	0.683	1.00
187_V	249_K	0.681	1.00
226_D	232_Q	0.678	1.00
256_G	259_M	0.677	1.00
90_E	100_I	0.675	1.00
239_S	242_K	0.673	1.00
151_L	161_L	0.673	1.00
173_K	206_V	0.669	1.00
66_K	318_E	0.669	1.00
143_A	149_T	0.669	1.00
180_Y	211_A	0.665	1.00
264_S	268_E	0.664	1.00
111_K	115_M	0.663	1.00
200_R	228_K	0.662	1.00
9_T	47_A	0.662	1.00
174_E	178_K	0.658	1.00
233_L	236_E	0.654	1.00
106_D	111_K	0.653	1.00
149_T	161_L	0.653	1.00
126_G	150_I	0.651	1.00
224_E	240_F	0.650	1.00
128_I	152_I	0.648	1.00
110_E	114_E	0.647	1.00
259_M	281_G	0.646	1.00
204_A	223_H	0.644	1.00
216_V	220_V	0.642	1.00
9_T	52_N	0.640	1.00
294_G	336_R	0.637	1.00
179_V	252_L	0.636	1.00
207_Y	218_G	0.631	1.00
264_S	292_G	0.631	1.00
153_D	199_P	0.630	1.00
150_I	313_V	0.629	1.00
291_I	294_G	0.629	1.00
237_L	261_K	0.629	1.00
54_R	117_L	0.629	1.00
315_K	325_Q	0.628	1.00
116_L	127_L	0.624	1.00
162_D	324_P	0.623	1.00
20_V	40_K	0.623	1.00
186_D	245_P	0.623	1.00
12_K	63_K	0.622	1.00
143_A	161_L	0.621	1.00
43_N	46_K	0.620	1.00
84_A	302_S	0.618	1.00
150_I	316_R	0.615	1.00
35_A	40_K	0.615	1.00
224_E	243_E	0.614	1.00
79_N	257_L	0.614	1.00
142_F	149_T	0.613	1.00
189_L	207_Y	0.612	1.00
263_I	267_E	0.611	1.00
49_A	52_N	0.611	1.00
14_V	25_V	0.608	1.00
255_N	283_D	0.607	1.00
25_V	28_Y	0.607	1.00
120_E	147_I	0.606	1.00
98_Y	317_I	0.604	1.00
230_K	287_W	0.602	1.00
316_R	319_G	0.601	1.00
87_R	303_H	0.601	1.00
126_G	309_A	0.601	1.00
187_V	207_Y	0.601	1.00
288_Y	297_T	0.600	1.00
113_R	138_V	0.600	1.00
168_N	202_E	0.600	1.00
153_D	168_N	0.597	1.00
260_L	287_W	0.596	1.00
88_G	302_S	0.596	1.00
73_V	115_M	0.594	1.00
228_K	254_L	0.594	1.00
173_K	176_L	0.593	1.00
137_D	140_R	0.591	1.00
85_A	302_S	0.587	1.00
260_L	285_T	0.585	1.00
266_M	269_L	0.584	1.00
178_K	280_A	0.584	1.00
296_T	333_V	0.584	1.00
36_I	41_V	0.583	1.00
101_M	122_H	0.582	1.00
192_E	200_R	0.580	1.00
186_D	248_K	0.578	1.00
150_I	164_V	0.578	1.00
27_R	36_I	0.577	1.00
303_H	306_G	0.576	1.00
25_V	48_I	0.575	1.00
32_K	36_I	0.575	1.00
70_I	126_G	0.575	1.00
81_F	85_A	0.572	1.00
138_V	141_A	0.570	1.00
282_F	300_Q	0.566	1.00
127_L	147_I	0.565	1.00
289_K	294_G	0.561	1.00
267_E	272_R	0.561	1.00
292_G	337_K	0.560	1.00
54_R	58_M	0.556	1.00
117_L	120_E	0.556	1.00
255_N	258_I	0.555	1.00
98_Y	125_E	0.555	1.00
93_C	314_L	0.552	1.00
230_K	261_K	0.551	1.00
298_I	331_A	0.549	1.00
218_G	223_H	0.549	1.00
312_R	316_R	0.548	1.00
70_I	317_I	0.548	1.00
208_Q	220_V	0.547	1.00
150_I	309_A	0.547	1.00
155_K	163_T	0.547	1.00
105_T	112_E	0.546	1.00
252_L	282_F	0.545	1.00
87_R	106_D	0.545	1.00
175_I	250_A	0.543	1.00
231_E	234_K	0.541	1.00
248_K	251_I	0.540	1.00
150_I	312_R	0.539	1.00
200_R	254_L	0.538	1.00
67_S	99_S	0.538	1.00
268_E	292_G	0.537	1.00
308_T	315_K	0.537	1.00
70_I	98_Y	0.535	1.00
271_L	274_P	0.535	1.00
60_Q	64_I	0.535	1.00
248_K	271_L	0.534	1.00
164_V	308_T	0.534	1.00
262_I	266_M	0.532	1.00
234_K	261_K	0.530	1.00
109_P	113_R	0.530	1.00
221_R	243_E	0.529	1.00
93_C	98_Y	0.529	1.00
204_A	218_G	0.523	1.00
84_A	286_E	0.522	1.00
20_V	25_V	0.522	1.00
18_A	28_Y	0.521	1.00
236_E	240_F	0.520	1.00
228_K	258_I	0.517	1.00
253_A	281_G	0.516	1.00
234_K	237_L	0.515	1.00
103_C	118_K	0.514	1.00
166_T	282_F	0.513	1.00
328_E	331_A	0.512	1.00
23_S	32_K	0.512	1.00
288_Y	295_I	0.511	1.00
25_V	44_I	0.511	1.00
305_M	329_L	0.510	1.00
119_L	124_V	0.510	1.00
204_A	225_I	0.510	1.00
113_R	141_A	0.509	1.00
69_L	125_E	0.508	1.00
301_P	305_M	0.508	1.00
80_P	257_L	0.506	1.00
141_A	145_Q	0.503	1.00
273_I	276_D	0.503	1.00
191_T	225_I	0.502	1.00
165_T	168_N	0.501	1.00
61_G	64_I	0.500	1.00
13_D	17_C	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3kjxA	2	0.9764	100	0.062	Contact Map
2hsgA	1	0.9617	100	0.068	Contact Map
2o20A	2	0.8083	100	0.069	Contact Map
3dbiA	2	0.8024	100	0.071	Contact Map
3bilA	2	0.7463	100	0.071	Contact Map
1qpzA	2	0.9676	100	0.073	Contact Map
3e3mA	2	0.7817	100	0.075	Contact Map
4o5aA	2	0.7817	100	0.083	Contact Map
3h5oA	2	0.7906	100	0.085	Contact Map
3ctpA	2	0.7788	100	0.093	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0106 seconds.