YPSC - BACSU - GREMLIN Contacts

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YPSC - Putative RNA methyltransferase YpsC

UniProt:	P50840	Sequences: MKKYTLIATAPMGIEAVVAKEVRDLGYECKVDNGKVIFEGDALAICRANLWLRTADRIKVQVASFKAKTFDELFEKTKAINWRSFIPENGKFPVIGKSVKSTLASVPDCQRIVKKAIVEKLKLQSGKANDWIEETGAEYKVEISLLKDQALITLDSSGTGLHKRGYRVDQGGAPIKETLAAALVQLTNWTPDRPFVDPFCGSGTIAIEAALIGQNIAPGFNRDFVSEDWEWIGKDLWNKARLEVEEKANYDQPLTIFASDIDHRMVQIAKENAEEAGLGDLIQFKQMQVKDFTTNLEFGVIVGNPPYGERLGEKKAVEQMYKEMGQAFEPLDTWSVYMLTSNENFEEAYGRKATKKRKLFNGFIKTDYYQYWSKVRPQRKKTENA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	385 (369)
Sequences:	2168 (1440)
Seq/√Len:	74.9

ECOLI - RLMKL
BACSU - YPSC

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
83_R	120_K	6.123	1.00
206_A	258_A	4.595	1.00
273_A	284_F	4.388	1.00
86_I	90_G	3.629	1.00
63_A	80_I	3.475	1.00
8_A	38_F	3.464	1.00
215_N	247_K	3.278	1.00
71_D	75_E	3.193	1.00
273_A	278_L	3.166	1.00
64_S	149_Q	3.118	1.00
299_G	334_W	3.088	1.00
113_V	143_I	2.948	1.00
7_I	35_K	2.855	1.00
81_N	84_S	2.841	1.00
38_F	48_A	2.824	1.00
117_I	141_V	2.813	1.00
119_E	122_K	2.768	1.00
8_A	58_I	2.761	1.00
41_D	44_A	2.701	1.00
171_G	265_M	2.688	1.00
40_G	44_A	2.561	1.00
175_I	339_L	2.557	1.00
183_L	368_Y	2.440	1.00
49_N	156_S	2.383	1.00
78_K	123_L	2.370	1.00
65_F	76_K	2.342	1.00
22_V	27_Y	2.338	1.00
27_Y	44_A	2.329	1.00
206_A	256_I	2.323	1.00
74_F	119_E	2.261	1.00
183_L	205_I	2.219	1.00
87_P	90_G	2.214	1.00
185_Q	212_I	2.210	1.00
356_K	367_D	2.203	1.00
77_T	113_V	2.203	1.00
77_T	152_I	2.171	1.00
96_G	109_C	2.150	1.00
43_L	239_K	2.144	1.00
10_A	18_V	2.130	1.00
288_Q	291_D	2.113	1.00
69_T	72_E	2.110	1.00
81_N	120_K	2.103	1.00
266_V	284_F	2.093	1.00
143_I	150_A	2.086	1.00
184_V	187_T	2.043	1.00
214_Q	281_L	2.031	1.00
66_K	149_Q	2.017	1.00
196_V	292_F	2.013	1.00
145_L	150_A	1.926	1.00
24_D	185_Q	1.860	1.00
6_L	45_I	1.860	1.00
266_V	286_Q	1.839	1.00
61_Q	64_S	1.828	1.00
196_V	259_S	1.779	1.00
195_F	302_V	1.764	1.00
187_T	300_V	1.755	1.00
17_V	54_T	1.753	1.00
47_R	243_E	1.751	1.00
54_T	185_Q	1.723	1.00
328_F	336_V	1.706	1.00
159_T	163_K	1.684	1.00
240_A	243_E	1.674	1.00
346_E	369_Y	1.663	1.00
104_A	107_P	1.649	1.00
113_V	152_I	1.641	1.00
50_L	240_A	1.623	1.00
269_A	284_F	1.613	1.00
324_M	328_F	1.610	1.00
95_I	140_K	1.600	0.99
313_E	316_A	1.598	0.99
273_A	282_I	1.594	0.99
263_H	286_Q	1.581	0.99
19_A	23_R	1.570	0.99
255_T	283_Q	1.548	0.99
46_C	236_L	1.542	0.99
91_K	138_E	1.535	0.99
8_A	48_A	1.533	0.99
103_L	109_C	1.529	0.99
48_A	58_I	1.523	0.99
343_E	365_K	1.515	0.99
187_T	337_Y	1.491	0.99
68_K	72_E	1.487	0.99
5_T	39_E	1.475	0.99
11_P	178_T	1.464	0.99
184_V	205_I	1.464	0.99
60_V	156_S	1.453	0.99
18_V	55_A	1.447	0.99
265_M	268_I	1.441	0.99
226_S	237_W	1.437	0.99
274_E	279_G	1.432	0.99
168_V	275_E	1.430	0.99
5_T	61_Q	1.427	0.99
51_W	244_V	1.425	0.99
337_Y	370_Q	1.416	0.99
45_I	156_S	1.414	0.99
61_Q	151_L	1.409	0.99
198_P	303_G	1.397	0.99
289_V	324_M	1.397	0.99
336_V	349_Y	1.388	0.99
259_S	287_M	1.386	0.98
258_A	269_A	1.369	0.98
8_A	22_V	1.369	0.98
195_F	206_A	1.365	0.98
354_T	372_W	1.363	0.98
86_I	121_L	1.361	0.98
43_L	240_A	1.353	0.98
206_A	284_F	1.340	0.98
59_K	153_T	1.328	0.98
78_K	119_E	1.326	0.98
143_I	152_I	1.322	0.98
48_A	52_L	1.318	0.98
360_F	365_K	1.316	0.98
71_D	112_I	1.310	0.98
242_L	246_E	1.309	0.98
96_G	110_Q	1.281	0.97
80_I	152_I	1.277	0.97
195_F	205_I	1.274	0.97
74_F	116_A	1.274	0.97
259_S	292_F	1.272	0.97
183_L	302_V	1.270	0.97
6_L	40_G	1.257	0.97
290_K	323_E	1.253	0.97
139_Y	231_W	1.239	0.97
303_G	338_M	1.233	0.97
57_R	155_D	1.228	0.97
183_L	359_L	1.216	0.97
278_L	284_F	1.213	0.96
49_N	157_S	1.194	0.96
86_I	139_Y	1.188	0.96
199_F	303_G	1.169	0.96
318_E	348_A	1.167	0.96
307_Y	361_N	1.157	0.95
104_A	108_D	1.156	0.95
220_F	248_A	1.155	0.95
217_A	244_V	1.151	0.95
189_W	195_F	1.149	0.95
109_C	143_I	1.143	0.95
83_R	124_Q	1.139	0.95
76_K	150_A	1.137	0.95
61_Q	153_T	1.135	0.95
303_G	324_M	1.131	0.95
37_I	61_Q	1.131	0.95
255_T	296_L	1.122	0.95
51_W	217_A	1.121	0.95
171_G	268_I	1.116	0.94
43_L	47_R	1.107	0.94
92_F	118_V	1.105	0.94
14_I	182_A	1.094	0.94
206_A	282_I	1.085	0.93
18_V	54_T	1.084	0.93
46_C	232_I	1.083	0.93
65_F	150_A	1.081	0.93
267_Q	270_K	1.077	0.93
46_C	240_A	1.071	0.93
211_L	278_L	1.070	0.93
233_G	236_L	1.064	0.93
98_S	101_S	1.063	0.93
19_A	31_V	1.048	0.92
107_P	111_R	1.047	0.92
234_K	238_N	1.045	0.92
114_K	118_V	1.044	0.92
184_V	302_V	1.026	0.91
213_G	254_L	1.024	0.91
271_E	274_E	1.020	0.91
184_V	195_F	1.019	0.91
56_D	160_G	1.019	0.91
169_D	271_E	1.018	0.91
312_G	316_A	1.014	0.91
207_I	276_A	1.013	0.91
157_S	225_V	1.012	0.91
360_F	363_F	1.011	0.91
195_F	209_A	1.008	0.91
97_K	144_S	0.998	0.90
8_A	55_A	0.998	0.90
108_D	111_R	0.992	0.90
93_P	134_E	0.991	0.90
237_W	244_V	0.990	0.90
325_G	350_G	0.986	0.90
321_Y	340_T	0.983	0.90
70_F	108_D	0.981	0.90
226_S	232_I	0.977	0.89
16_A	20_K	0.976	0.89
98_S	106_V	0.974	0.89
142_E	153_T	0.974	0.89
345_F	349_Y	0.974	0.89
78_K	120_K	0.972	0.89
45_I	60_V	0.969	0.89
6_L	38_F	0.969	0.89
155_D	158_G	0.967	0.89
289_V	327_A	0.965	0.89
298_F	333_T	0.962	0.89
22_V	48_A	0.959	0.88
80_I	120_K	0.958	0.88
106_V	109_C	0.950	0.88
20_K	23_R	0.949	0.88
52_L	55_A	0.946	0.88
227_E	241_R	0.946	0.88
95_I	142_E	0.944	0.88
56_D	176_K	0.942	0.88
133_E	137_A	0.937	0.87
249_N	252_Q	0.936	0.87
343_E	369_Y	0.936	0.87
87_P	230_E	0.935	0.87
206_A	273_A	0.928	0.87
18_V	185_Q	0.926	0.87
68_K	102_T	0.923	0.86
118_V	132_I	0.920	0.86
195_F	256_I	0.920	0.86
353_A	356_K	0.919	0.86
66_K	148_D	0.919	0.86
160_G	176_K	0.915	0.86
67_A	72_E	0.913	0.86
88_E	127_K	0.908	0.86
17_V	182_A	0.908	0.86
223_D	227_E	0.905	0.85
38_F	58_I	0.904	0.85
29_C	36_V	0.900	0.85
89_N	135_T	0.898	0.85
186_L	359_L	0.885	0.84
75_E	78_K	0.881	0.84
226_S	241_R	0.875	0.83
193_R	300_V	0.875	0.83
317_V	321_Y	0.874	0.83
324_M	336_V	0.873	0.83
271_E	275_E	0.870	0.83
94_V	113_V	0.868	0.83
211_L	216_I	0.866	0.83
340_T	346_E	0.862	0.82
96_G	106_V	0.861	0.82
92_F	139_Y	0.859	0.82
326_Q	330_P	0.853	0.82
77_T	94_V	0.852	0.82
92_F	121_L	0.849	0.81
335_S	370_Q	0.847	0.81
105_S	108_D	0.847	0.81
19_A	29_C	0.846	0.81
218_P	244_V	0.846	0.81
358_K	367_D	0.843	0.81
138_E	225_V	0.842	0.81
141_V	152_I	0.838	0.81
42_A	231_W	0.835	0.80
99_V	146_L	0.834	0.80
217_A	220_F	0.833	0.80
323_E	326_Q	0.832	0.80
89_N	127_K	0.832	0.80
23_R	29_C	0.826	0.80
20_K	24_D	0.826	0.80
63_A	81_N	0.824	0.79
67_A	150_A	0.821	0.79
165_G	177_E	0.820	0.79
5_T	37_I	0.819	0.79
207_I	278_L	0.817	0.79
210_A	276_A	0.813	0.79
196_V	257_F	0.810	0.78
76_K	79_A	0.809	0.78
210_A	278_L	0.807	0.78
207_I	282_I	0.806	0.78
193_R	335_S	0.801	0.78
17_V	186_L	0.799	0.77
216_I	220_F	0.798	0.77
361_N	366_T	0.796	0.77
20_K	188_N	0.794	0.77
220_F	245_E	0.792	0.77
82_W	117_I	0.791	0.77
98_S	109_C	0.788	0.76
166_Y	207_I	0.786	0.76
170_Q	268_I	0.785	0.76
170_Q	265_M	0.782	0.76
62_V	85_F	0.781	0.76
118_V	122_K	0.778	0.75
30_K	37_I	0.775	0.75
337_Y	368_Y	0.775	0.75
317_V	345_F	0.775	0.75
197_D	306_P	0.774	0.75
343_E	356_K	0.763	0.74
318_E	342_N	0.762	0.74
83_R	121_L	0.759	0.74
115_K	119_E	0.758	0.74
314_K	318_E	0.755	0.73
184_V	300_V	0.753	0.73
288_Q	323_E	0.753	0.73
184_V	206_A	0.749	0.73
6_L	27_Y	0.749	0.73
214_Q	252_Q	0.746	0.72
214_Q	254_L	0.745	0.72
324_M	349_Y	0.745	0.72
10_A	160_G	0.744	0.72
301_I	328_F	0.743	0.72
227_E	232_I	0.742	0.72
357_R	370_Q	0.741	0.72
202_S	304_N	0.738	0.72
194_P	299_G	0.730	0.71
266_V	269_A	0.729	0.71
128_A	131_W	0.728	0.71
338_M	371_Y	0.726	0.70
6_L	60_V	0.724	0.70
186_L	357_R	0.720	0.70
156_S	229_W	0.720	0.70
101_S	148_D	0.717	0.69
259_S	283_Q	0.717	0.69
92_F	141_V	0.715	0.69
17_V	185_Q	0.715	0.69
312_G	345_F	0.714	0.69
294_T	331_L	0.714	0.69
140_K	225_V	0.713	0.69
267_Q	271_E	0.710	0.69
174_P	177_E	0.709	0.69
346_E	349_Y	0.709	0.69
17_V	20_K	0.708	0.68
169_D	268_I	0.707	0.68
109_C	145_L	0.705	0.68
258_A	282_I	0.705	0.68
224_F	227_E	0.700	0.68
356_K	365_K	0.699	0.67
214_Q	278_L	0.698	0.67
115_K	121_L	0.698	0.67
85_F	231_W	0.698	0.67
171_G	269_A	0.697	0.67
328_F	331_L	0.696	0.67
191_P	213_G	0.695	0.67
90_G	139_Y	0.691	0.67
32_D	37_I	0.690	0.66
196_V	294_T	0.688	0.66
340_T	369_Y	0.686	0.66
193_R	298_F	0.686	0.66
194_P	255_T	0.685	0.66
23_R	28_E	0.683	0.66
183_L	339_L	0.680	0.65
214_Q	280_D	0.679	0.65
22_V	44_A	0.678	0.65
267_Q	285_K	0.677	0.65
73_L	103_L	0.676	0.65
88_E	121_L	0.675	0.65
339_L	366_T	0.674	0.65
202_S	272_N	0.673	0.64
324_M	338_M	0.672	0.64
289_V	309_E	0.667	0.64
311_L	326_Q	0.667	0.64
265_M	269_A	0.663	0.63
225_V	228_D	0.658	0.63
184_V	213_G	0.658	0.63
20_K	185_Q	0.658	0.63
174_P	304_N	0.657	0.63
62_V	80_I	0.656	0.63
172_G	264_R	0.654	0.62
44_A	48_A	0.654	0.62
50_L	237_W	0.654	0.62
239_K	279_G	0.654	0.62
248_A	278_L	0.652	0.62
307_Y	364_I	0.652	0.62
25_L	182_A	0.650	0.62
169_D	275_E	0.650	0.62
120_K	124_Q	0.650	0.62
111_R	115_K	0.649	0.62
72_E	76_K	0.649	0.62
78_K	81_N	0.649	0.62
132_I	136_G	0.648	0.62
171_G	364_I	0.648	0.62
43_L	236_L	0.645	0.61
123_L	126_G	0.645	0.61
106_V	229_W	0.644	0.61
270_K	285_K	0.644	0.61
114_K	134_E	0.644	0.61
52_L	58_I	0.639	0.60
100_K	104_A	0.638	0.60
238_N	241_R	0.638	0.60
32_D	35_K	0.636	0.60
236_L	239_K	0.635	0.60
122_K	131_W	0.633	0.60
139_Y	229_W	0.633	0.60
162_H	178_T	0.633	0.60
359_L	368_Y	0.632	0.60
27_Y	45_I	0.631	0.60
96_G	143_I	0.630	0.59
177_E	204_T	0.629	0.59
190_T	193_R	0.627	0.59
283_Q	287_M	0.627	0.59
55_A	178_T	0.627	0.59
42_A	232_I	0.627	0.59
53_R	181_A	0.626	0.59
241_R	245_E	0.625	0.59
21_E	25_L	0.625	0.59
80_I	113_V	0.623	0.59
317_V	340_T	0.623	0.59
249_N	253_P	0.621	0.58
292_F	331_L	0.621	0.58
189_W	209_A	0.620	0.58
270_K	279_G	0.620	0.58
301_I	336_V	0.620	0.58
205_I	284_F	0.618	0.58
243_E	247_K	0.617	0.58
4_Y	39_E	0.615	0.58
261_I	288_Q	0.613	0.57
328_F	349_Y	0.613	0.57
206_A	212_I	0.613	0.57
179_L	309_E	0.611	0.57
239_K	243_E	0.611	0.57
329_E	351_R	0.610	0.57
12_M	360_F	0.610	0.57
112_I	115_K	0.609	0.57
45_I	49_N	0.607	0.57
7_I	37_I	0.606	0.56
189_W	213_G	0.606	0.56
82_W	141_V	0.605	0.56
210_A	256_I	0.602	0.56
77_T	143_I	0.600	0.56
115_K	118_V	0.600	0.56
55_A	58_I	0.600	0.56
64_S	151_L	0.597	0.55
200_C	258_A	0.596	0.55
119_E	128_A	0.593	0.55
361_N	364_I	0.593	0.55
42_A	236_L	0.591	0.55
16_A	31_V	0.591	0.55
105_S	110_Q	0.590	0.54
12_M	33_N	0.590	0.54
322_K	326_Q	0.590	0.54
10_A	58_I	0.589	0.54
266_V	270_K	0.587	0.54
360_F	364_I	0.587	0.54
314_K	342_N	0.587	0.54
346_E	371_Y	0.587	0.54
42_A	46_C	0.587	0.54
111_R	119_E	0.586	0.54
60_V	231_W	0.585	0.54
140_K	160_G	0.583	0.54
97_K	142_E	0.582	0.53
139_Y	266_V	0.582	0.53
163_K	262_D	0.582	0.53
86_I	117_I	0.581	0.53
7_I	11_P	0.580	0.53
62_V	152_I	0.579	0.53
8_A	27_Y	0.578	0.53
40_G	48_A	0.577	0.53
46_C	237_W	0.576	0.53
327_A	330_P	0.575	0.53
339_L	348_A	0.574	0.52
306_P	310_R	0.573	0.52
173_A	310_R	0.569	0.52
69_T	104_A	0.569	0.52
216_I	248_A	0.568	0.52
56_D	178_T	0.568	0.52
189_W	300_V	0.567	0.52
317_V	342_N	0.566	0.51
7_I	153_T	0.566	0.51
341_S	355_K	0.566	0.51
11_P	171_G	0.565	0.51
177_E	202_S	0.564	0.51
189_W	299_G	0.562	0.51
316_A	326_Q	0.562	0.51
335_S	373_S	0.559	0.51
74_F	115_K	0.559	0.51
259_S	285_K	0.557	0.50
7_I	61_Q	0.557	0.50
4_Y	40_G	0.557	0.50
182_A	186_L	0.557	0.50
320_M	324_M	0.556	0.50
285_K	288_Q	0.556	0.50
47_R	246_E	0.556	0.50
157_S	226_S	0.555	0.50
75_E	79_A	0.555	0.50
192_D	253_P	0.553	0.50
31_V	207_I	0.552	0.50
292_F	327_A	0.552	0.50
57_R	217_A	0.552	0.50
93_P	140_K	0.552	0.50
27_Y	41_D	0.551	0.50
283_Q	297_E	0.551	0.50
12_M	34_G	0.548	0.49
312_G	317_V	0.546	0.49
169_D	264_R	0.545	0.49
62_V	154_L	0.544	0.49
73_L	150_A	0.543	0.49
117_I	120_K	0.542	0.48
292_F	301_I	0.542	0.48
102_T	148_D	0.542	0.48
9_T	51_W	0.541	0.48
164_R	208_E	0.540	0.48
289_V	292_F	0.539	0.48
107_P	110_Q	0.539	0.48
47_R	51_W	0.539	0.48
108_D	115_K	0.538	0.48
144_S	176_K	0.537	0.48
339_L	342_N	0.537	0.48
90_G	230_E	0.537	0.48
220_F	244_V	0.536	0.48
302_V	368_Y	0.536	0.48
183_L	199_F	0.536	0.48
51_W	247_K	0.536	0.48
29_C	39_E	0.535	0.48
340_T	349_Y	0.535	0.48
9_T	56_D	0.535	0.48
27_Y	48_A	0.534	0.47
5_T	302_V	0.533	0.47
74_F	112_I	0.532	0.47
73_L	109_C	0.532	0.47
194_P	296_L	0.531	0.47
73_L	113_V	0.531	0.47
49_N	226_S	0.531	0.47
77_T	109_C	0.531	0.47
25_L	54_T	0.530	0.47
173_A	204_T	0.530	0.47
179_L	361_N	0.529	0.47
203_G	273_A	0.528	0.47
42_A	60_V	0.528	0.47
201_G	306_P	0.527	0.47
10_A	157_S	0.526	0.46
257_F	283_Q	0.526	0.46
74_F	111_R	0.526	0.46
278_L	281_L	0.526	0.46
127_K	131_W	0.525	0.46
283_Q	286_Q	0.524	0.46
234_K	242_L	0.523	0.46
230_E	233_G	0.522	0.46
293_T	330_P	0.522	0.46
286_Q	291_D	0.522	0.46
300_V	337_Y	0.521	0.46
311_L	352_K	0.521	0.46
356_K	369_Y	0.520	0.46
166_Y	211_L	0.520	0.46
204_T	310_R	0.519	0.46
219_G	244_V	0.519	0.46
119_E	131_W	0.518	0.45
71_D	78_K	0.518	0.45
35_K	144_S	0.517	0.45
27_Y	38_F	0.517	0.45
183_L	341_S	0.517	0.45
199_F	320_M	0.516	0.45
144_S	153_T	0.515	0.45
11_P	365_K	0.515	0.45
217_A	248_A	0.514	0.45
319_Q	322_K	0.514	0.45
174_P	202_S	0.513	0.45
96_G	142_E	0.513	0.45
7_I	12_M	0.513	0.45
239_K	255_T	0.512	0.45
204_T	304_N	0.512	0.45
162_H	170_Q	0.510	0.44
194_P	297_E	0.509	0.44
177_E	304_N	0.508	0.44
64_S	94_V	0.507	0.44
152_I	241_R	0.506	0.44
236_L	240_A	0.506	0.44
109_C	152_I	0.506	0.44
108_D	131_W	0.506	0.44
344_N	348_A	0.505	0.44
227_E	234_K	0.503	0.44
173_A	304_N	0.503	0.44
143_I	153_T	0.503	0.44
49_N	158_G	0.502	0.43
67_A	76_K	0.502	0.43
289_V	323_E	0.502	0.43
53_R	219_G	0.501	0.43
173_A	180_A	0.500	0.43

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3lduA	1	0.974	100	0.227	Contact Map
3ldgA	1	0.9688	100	0.23	Contact Map
3k0bA	1	0.9584	100	0.24	Contact Map
3v97A	1	0.9662	100	0.245	Contact Map
3tm4A	1	0.8468	100	0.47	Contact Map
3tmaA	2	0.8286	100	0.547	Contact Map
3s1sA	1	0.8	99.8	0.838	Contact Map
2r6zA	2	0.5558	99.5	0.867	Contact Map
1o9gA	1	0.5065	99.5	0.87	Contact Map
2okcA	1	0.787	99.5	0.873	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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