GREMLIN Database
YPVA - Probable ATP-dependent helicase YpvA
UniProt: P50831 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 641 (574)
Sequences: 4177 (3137)
Seq/√Len: 130.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
457_D460_E6.3591.00
78_A255_V4.3621.00
476_Q508_L4.2791.00
496_F505_F4.2741.00
259_G424_F4.2451.00
229_Y256_F4.0041.00
509_S542_C3.9151.00
485_I492_T3.7841.00
54_F253_A3.5661.00
41_D45_F3.3921.00
482_I561_T3.3331.00
496_F542_C3.2861.00
46_M62_A3.2691.00
488_Y492_T3.0261.00
38_D609_N2.8341.00
439_A449_S2.8001.00
491_R558_K2.7801.00
109_I122_T2.6701.00
484_T616_H2.6521.00
605_L613_G2.6421.00
519_F539_T2.6211.00
53_A60_M2.6001.00
166_M170_Y2.5681.00
499_F544_V2.5621.00
506_K520_F2.5411.00
58_K448_L2.4711.00
617_I622_E2.4621.00
98_L101_Q2.4441.00
49_Q450_L2.4251.00
172_Y177_Q2.3621.00
340_E343_R2.3431.00
46_M425_S2.3241.00
411_L416_F2.3211.00
482_I494_V2.3091.00
303_L307_D2.3021.00
547_W601_G2.2971.00
175_R186_W2.2871.00
531_E535_E2.2821.00
78_A89_A2.2761.00
71_T102_L2.2691.00
100_E104_K2.2601.00
123_R219_T2.2301.00
412_G417_S2.1591.00
42_E452_V2.1471.00
500_E504_E2.1171.00
602_I615_I2.0981.00
52_R56_E2.0721.00
310_F314_S2.0561.00
484_T559_N2.0281.00
416_F424_F2.0271.00
559_N616_H2.0241.00
256_F262_L2.0181.00
553_P608_S1.9911.00
480_E512_W1.9821.00
492_T559_N1.9761.00
307_D310_F1.9741.00
261_L548_E1.9691.00
479_A508_L1.9661.00
166_M169_F1.9531.00
475_E479_A1.9281.00
34_E37_F1.9251.00
367_S371_E1.9071.00
481_T618_Y1.9071.00
490_G555_D1.9061.00
579_N582_K1.9041.00
598_V617_I1.9011.00
430_S451_T1.8931.00
368_V371_E1.8731.00
44_V48_F1.8511.00
536_E539_T1.8411.00
491_R516_Y1.8401.00
303_L309_F1.8181.00
595_L630_V1.8121.00
197_C200_C1.8031.00
53_A58_K1.7921.00
485_I540_V1.7831.00
582_K585_P1.7801.00
273_R401_V1.7741.00
517_P532_K1.7691.00
61_F439_A1.7641.00
102_L105_K1.7521.00
555_D558_K1.7441.00
496_F502_L1.7411.00
561_T618_Y1.7391.00
92_A226_H1.7341.00
54_F423_I1.7291.00
99_I103_V1.7281.00
109_I113_A1.7201.00
273_R399_T1.6951.00
538_E556_A1.6951.00
295_F298_L1.6841.00
438_I442_L1.6641.00
61_F438_I1.6331.00
502_L520_F1.6291.00
74_Y425_S1.6291.00
435_F449_S1.6091.00
371_E375_Q1.6031.00
337_A345_L1.5821.00
579_N583_K1.5801.00
303_L310_F1.5741.00
133_C206_C1.5651.00
502_L542_C1.5601.00
346_D349_G1.5561.00
306_N309_F1.5521.00
517_P536_E1.5481.00
147_D150_L1.5421.00
53_A421_P1.5341.00
57_K420_I1.5291.00
73_V77_F1.5151.00
310_F317_S1.5131.00
370_E375_Q1.5131.00
578_R590_D1.5121.00
134_L137_L1.5121.00
488_Y559_N1.5101.00
125_S215_Y1.5101.00
528_S531_E1.5021.00
489_K516_Y1.5001.00
368_V372_Y1.4941.00
419_K422_Y1.4911.00
181_L184_E1.4851.00
519_F536_E1.4841.00
310_F313_L1.4831.00
510_A523_D1.4701.00
602_I617_I1.4691.00
537_E555_D1.4681.00
560_V605_L1.4651.00
305_A309_F1.4641.00
98_L102_L1.4631.00
598_V630_V1.4601.00
578_R582_K1.4511.00
125_S222_I1.4481.00
49_Q448_L1.4481.00
534_Q556_A1.4261.00
50_L77_F1.4191.00
309_F312_V1.4191.00
439_A447_Y1.4171.00
299_I302_A1.4071.00
474_A478_T1.4041.00
307_D311_Y1.4031.00
479_A505_F1.4021.00
483_E486_K1.4011.00
99_I105_K1.3991.00
299_I306_N1.3981.00
339_D343_R1.3951.00
499_F502_L1.3951.00
50_L423_I1.3871.00
565_L594_M1.3871.00
527_S531_E1.3821.00
477_K480_E1.3781.00
375_Q379_S1.3781.00
99_I104_K1.3781.00
343_R346_D1.3771.00
99_I102_L1.3741.00
350_E353_V1.3721.00
558_K612_S1.3721.00
302_A306_N1.3711.00
562_I615_I1.3681.00
494_V540_V1.3581.00
306_N320_V1.3481.00
316_E319_E1.3451.00
90_I251_H1.3391.00
484_T561_T1.3381.00
254_V422_Y1.3351.00
587_E625_R1.3341.00
93_C99_I1.3321.00
133_C200_C1.3321.00
308_E311_Y1.3291.00
90_I254_V1.3161.00
101_Q104_K1.3131.00
254_V419_K1.3121.00
166_M172_Y1.3111.00
552_I556_A1.3081.00
337_A344_L1.2981.00
149_W152_L1.2971.00
365_E368_V1.2941.00
310_F316_E1.2941.00
581_A589_V1.2901.00
372_Y375_Q1.2871.00
491_R537_E1.2871.00
98_L103_V1.2841.00
562_I602_I1.2821.00
124_L223_I1.2791.00
519_F532_K1.2791.00
46_M50_L1.2761.00
584_D587_E1.2731.00
367_S370_E1.2721.00
575_T578_R1.2651.00
120_I221_L1.2561.00
587_E591_L1.2551.00
263_E441_S1.2541.00
499_F503_N1.2541.00
366_L369_V1.2491.00
170_Y173_G1.2481.00
312_V315_E1.2431.00
412_G445_H1.2431.00
532_K535_E1.2401.00
126_K174_D1.2391.00
306_N310_F1.2381.00
306_N311_Y1.2361.00
303_L311_Y1.2251.00
60_M423_I1.2211.00
146_D150_L1.2211.00
479_A482_I1.2171.00
303_L313_L1.2151.00
302_A310_F1.2131.00
567_F626_I1.2060.99
181_L186_W1.2060.99
45_F48_F1.2040.99
497_P564_S1.2020.99
476_Q480_E1.2000.99
166_M173_G1.1990.99
61_F442_L1.1900.99
314_S319_E1.1850.99
89_A255_V1.1810.99
368_V373_V1.1760.99
344_L348_I1.1760.99
61_F429_L1.1760.99
493_L543_S1.1760.99
213_D217_K1.1740.99
299_I310_F1.1670.99
348_I352_L1.1640.99
529_L541_L1.1620.99
96_E130_Q1.1610.99
121_D220_D1.1580.99
373_V377_A1.1580.99
101_Q105_K1.1550.99
229_Y254_V1.1510.99
338_A343_R1.1450.99
470_T473_D1.1380.99
300_E304_L1.1360.99
369_V372_Y1.1340.99
528_S532_K1.1310.99
49_Q60_M1.1300.99
480_E483_E1.1270.99
63_E451_T1.1240.99
569_P577_K1.1240.99
294_E298_L1.1200.99
198_L201_D1.1190.99
370_E374_E1.1170.99
567_F591_L1.1140.99
109_I223_I1.1070.99
146_D149_W1.1020.99
298_L301_D1.0980.99
574_F578_R1.0930.99
87_K252_S1.0920.99
230_M266_A1.0920.99
317_S320_V1.0880.99
349_G352_L1.0880.99
65_G452_V1.0870.99
526_I545_H1.0860.99
299_I319_E1.0850.99
503_N507_E1.0840.99
97_T101_Q1.0800.99
478_T481_T1.0770.99
368_V375_Q1.0760.99
253_A421_P1.0750.99
319_E322_G1.0740.99
91_I102_L1.0710.99
105_K111_K1.0710.99
299_I312_V1.0620.99
424_F438_I1.0610.99
461_Q606_I1.0590.99
506_K510_A1.0580.99
365_E371_E1.0560.99
569_P573_V1.0550.99
604_R607_R1.0540.99
94_A265_A1.0470.99
302_A309_F1.0450.99
339_D344_L1.0450.99
475_E505_F1.0450.99
455_P554_G1.0440.99
264_F593_Y1.0400.98
42_E453_D1.0370.98
336_K339_D1.0370.98
526_I546_L1.0350.98
230_M262_L1.0310.98
267_Q577_K1.0310.98
132_L206_C1.0310.98
474_A481_T1.0190.98
337_A340_E1.0190.98
508_L512_W1.0190.98
504_E507_E1.0160.98
296_A300_E1.0140.98
495_L547_W1.0120.98
503_N523_D1.0120.98
62_A452_V1.0120.98
401_V573_V1.0070.98
557_L605_L1.0060.98
99_I225_S1.0060.98
522_G525_E1.0060.98
103_V223_I1.0000.98
298_L303_L1.0000.98
351_A355_E0.9950.98
430_S435_F0.9950.98
79_I221_L0.9920.98
345_L348_I0.9920.98
339_D342_C0.9910.98
603_G607_R0.9900.98
624_E627_I0.9850.98
298_L320_V0.9840.98
576_A579_N0.9830.98
574_F589_V0.9810.98
332_H336_K0.9790.98
305_A308_E0.9740.98
133_C197_C0.9740.98
71_T256_F0.9610.97
307_D315_E0.9600.97
149_W173_G0.9580.97
520_F523_D0.9560.97
125_S224_C0.9530.97
469_K481_T0.9520.97
186_W189_V0.9500.97
200_C206_C0.9490.97
343_R350_E0.9490.97
503_N520_F0.9470.97
303_L312_V0.9470.97
575_T579_N0.9410.97
559_N614_S0.9400.97
337_A347_K0.9370.97
79_I120_I0.9360.97
370_E376_M0.9280.97
83_R220_D0.9250.97
344_L349_G0.9240.97
306_N312_V0.9220.97
338_A342_C0.9210.97
561_T616_H0.9200.97
378_Y381_S0.9190.97
303_L317_S0.9190.97
537_E556_A0.9190.97
359_Y362_D0.9180.97
309_F317_S0.9150.97
293_E296_A0.9140.97
311_Y314_S0.9120.97
518_I542_C0.9110.96
305_A310_F0.9110.96
132_L137_L0.9100.96
49_Q452_V0.9100.96
456_Y461_Q0.9090.96
441_S577_K0.9090.96
59_V62_A0.9080.96
341_L344_L0.9070.96
40_R64_A0.9070.96
180_N184_E0.9060.96
310_F320_V0.9040.96
92_A229_Y0.9010.96
334_V341_L0.8990.96
573_V577_K0.8980.96
314_S318_K0.8980.96
483_E487_R0.8960.96
49_Q52_R0.8950.96
96_E99_I0.8950.96
54_F421_P0.8950.96
134_L138_E0.8950.96
40_R43_Q0.8950.96
294_E315_E0.8910.96
71_T75_L0.8910.96
570_H575_T0.8910.96
296_A302_A0.8890.96
93_C225_S0.8880.96
314_S322_G0.8880.96
100_E103_V0.8870.96
466_L481_T0.8810.96
470_T475_E0.8810.96
140_T145_D0.8800.96
113_A120_I0.8730.96
59_V421_P0.8710.95
134_L207_G0.8700.95
522_G529_L0.8700.95
374_E381_S0.8650.95
200_C203_R0.8610.95
301_D318_K0.8590.95
276_Q280_E0.8590.95
180_N183_N0.8590.95
365_E370_E0.8580.95
100_E527_S0.8580.95
340_E344_L0.8570.95
478_T482_I0.8550.95
475_E478_T0.8540.95
94_A261_L0.8540.95
224_C229_Y0.8540.95
493_L601_G0.8510.95
596_L599_R0.8500.95
256_F424_F0.8490.95
491_R559_N0.8490.95
42_E68_T0.8440.95
628_D632_K0.8430.95
296_A301_D0.8420.95
88_P219_T0.8350.94
501_E563_W0.8350.94
166_M171_P0.8340.94
103_V122_T0.8300.94
299_I309_F0.8280.94
295_F301_D0.8270.94
98_L104_K0.8260.94
122_T221_L0.8250.94
493_L560_V0.8240.94
486_K515_P0.8240.94
295_F303_L0.8230.94
302_A317_S0.8220.94
557_L613_G0.8220.94
136_K139_K0.8210.94
166_M177_Q0.8200.94
111_K114_E0.8190.94
569_P572_P0.8180.94
54_F78_A0.8180.94
600_Q603_G0.8170.94
479_A509_S0.8170.94
324_H327_E0.8170.94
144_S147_D0.8160.94
39_L44_V0.8150.94
370_E373_V0.8140.94
595_L633_V0.8140.94
121_D214_Y0.8130.93
48_F52_R0.8130.93
500_E503_N0.8130.93
505_F508_L0.8110.93
317_S321_A0.8110.93
504_E508_L0.8110.93
589_V593_Y0.8100.93
109_I221_L0.8100.93
188_D191_Y0.8040.93
65_G454_S0.8010.93
478_T618_Y0.8010.93
270_L410_V0.8010.93
51_E80_S0.7990.93
302_A319_E0.7990.93
310_F315_E0.7980.93
488_Y558_K0.7960.93
338_A346_D0.7950.93
295_F300_E0.7920.93
371_E374_E0.7910.93
224_C228_F0.7900.92
595_L629_E0.7900.92
305_A312_V0.7900.92
46_M452_V0.7870.92
494_V542_C0.7850.92
276_Q398_S0.7830.92
294_E313_L0.7790.92
426_S551_D0.7790.92
571_D574_F0.7770.92
368_V376_M0.7740.92
508_L511_A0.7740.92
369_V375_Q0.7740.92
53_A59_V0.7730.92
275_K399_T0.7730.92
392_E401_V0.7720.92
295_F308_E0.7710.92
530_V552_I0.7700.91
74_Y91_I0.7690.91
372_Y379_S0.7690.91
295_F314_S0.7670.91
337_A342_C0.7670.91
574_F590_D0.7670.91
383_Y389_S0.7640.91
416_F422_Y0.7640.91
94_A98_L0.7620.91
474_A479_A0.7620.91
75_L102_L0.7620.91
471_D475_E0.7620.91
103_V124_L0.7610.91
65_G455_P0.7580.91
544_V547_W0.7570.91
351_A357_E0.7560.91
300_E303_L0.7560.91
569_P575_T0.7550.91
82_A86_G0.7550.91
260_H426_S0.7550.91
123_R211_S0.7530.91
128_H232_H0.7520.91
505_F542_C0.7500.90
411_L442_L0.7450.90
295_F310_F0.7430.90
51_E55_K0.7420.90
547_W599_R0.7420.90
569_P574_F0.7410.90
353_V357_E0.7410.90
338_A348_I0.7410.90
63_E430_S0.7390.90
145_D149_W0.7380.90
125_S211_S0.7370.90
568_P593_Y0.7350.89
367_S375_Q0.7350.89
367_S373_V0.7350.89
139_K144_S0.7350.89
113_A117_D0.7350.89
347_K357_E0.7350.89
295_F305_A0.7340.89
309_F315_E0.7290.89
303_L308_E0.7290.89
141_M146_D0.7270.89
570_H586_F0.7250.89
267_Q271_T0.7240.89
514_L517_P0.7240.89
296_A310_F0.7240.89
296_A303_L0.7240.89
465_N616_H0.7230.89
295_F302_A0.7210.89
342_C347_K0.7210.89
66_V405_R0.7210.89
482_I509_S0.7210.89
67_G70_K0.7200.89
76_L81_Y0.7200.89
466_L469_K0.7200.89
506_K518_I0.7180.88
304_L308_E0.7180.88
299_I313_L0.7180.88
591_L625_R0.7170.88
174_D177_Q0.7170.88
320_V324_H0.7150.88
80_S84_Y0.7140.88
76_L80_S0.7140.88
567_F586_F0.7120.88
507_E510_A0.7080.88
337_A341_L0.7080.88
162_E166_M0.7070.88
301_D313_L0.7050.87
348_I351_A0.7050.87
562_I598_V0.7040.87
572_P575_T0.7040.87
622_E631_K0.7040.87
486_K514_L0.7030.87
296_A313_L0.7030.87
190_S193_S0.7020.87
304_L310_F0.7020.87
163_S166_M0.7010.87
263_E438_I0.7000.87
298_L309_F0.7000.87
531_E534_Q0.6990.87
350_E354_F0.6980.87
227_D269_A0.6980.87
624_E628_D0.6980.87
138_E202_M0.6970.87
116_L120_I0.6970.87
352_L360_T0.6950.87
300_E322_G0.6950.87
309_F313_L0.6940.87
431_E595_L0.6940.87
52_R448_L0.6930.87
344_L347_K0.6910.86
376_M380_L0.6900.86
297_E300_E0.6900.86
490_G558_K0.6900.86
347_K352_L0.6890.86
168_R171_P0.6880.86
473_D481_T0.6870.86
574_F577_K0.6870.86
507_E511_A0.6870.86
349_G357_E0.6860.86
332_H335_K0.6860.86
516_Y521_E0.6850.86
376_M381_S0.6850.86
135_K201_D0.6840.86
294_E322_G0.6840.86
61_F444_I0.6820.86
183_N193_S0.6810.86
600_Q607_R0.6810.86
521_E586_F0.6800.86
310_F319_E0.6790.85
574_F581_A0.6790.85
160_V167_Q0.6770.85
127_S225_S0.6760.85
337_A346_D0.6760.85
464_I617_I0.6740.85
265_A268_K0.6740.85
351_A358_M0.6740.85
600_Q604_R0.6730.85
147_D151_D0.6720.85
148_K152_L0.6700.85
127_S130_Q0.6690.85
372_Y377_A0.6690.85
81_Y253_A0.6680.85
275_K278_T0.6680.85
141_M164_Q0.6680.85
280_E284_E0.6670.84
228_F231_E0.6670.84
527_S555_D0.6660.84
489_K538_E0.6660.84
298_L310_F0.6650.84
517_P539_T0.6650.84
336_K343_R0.6640.84
53_A423_I0.6640.84
267_Q403_M0.6640.84
96_E101_Q0.6600.84
306_N314_S0.6570.84
484_T618_Y0.6560.83
197_C206_C0.6540.83
453_D632_K0.6540.83
78_A253_A0.6520.83
365_E379_S0.6510.83
493_L552_I0.6490.83
366_L377_A0.6490.83
472_M481_T0.6480.83
525_E528_S0.6470.83
94_A97_T0.6440.82
595_L598_V0.6430.82
350_E357_E0.6430.82
296_A325_R0.6420.82
140_T148_K0.6420.82
320_V323_S0.6400.82
207_G564_S0.6400.82
128_H191_Y0.6390.82
299_I305_A0.6390.82
516_Y540_V0.6380.82
228_F232_H0.6380.82
74_Y226_H0.6370.82
170_Y177_Q0.6360.82
47_A77_F0.6360.82
364_Y372_Y0.6340.81
371_E378_Y0.6340.81
333_R336_K0.6340.81
62_A450_L0.6340.81
387_A402_V0.6330.81
226_H232_H0.6320.81
126_K130_Q0.6320.81
435_F439_A0.6310.81
366_L371_E0.6300.81
596_L606_I0.6290.81
310_F323_S0.6290.81
50_L74_Y0.6280.81
533_F539_T0.6270.81
182_S185_E0.6260.81
336_K340_E0.6260.81
371_E376_M0.6260.81
161_H165_A0.6240.80
93_C98_L0.6220.80
126_K225_S0.6220.80
306_N313_L0.6210.80
214_Y219_T0.6210.80
98_L225_S0.6210.80
475_E501_E0.6210.80
478_T563_W0.6200.80
346_D352_L0.6190.80
227_D265_A0.6190.80
477_K481_T0.6180.80
308_E316_E0.6170.80
520_F524_E0.6170.80
302_A305_A0.6170.80
95_D98_L0.6170.80
36_G40_R0.6170.80
526_I530_V0.6150.79
377_A381_S0.6150.79
337_A349_G0.6150.79
476_Q504_E0.6150.79
72_L76_L0.6150.79
208_L212_R0.6130.79
506_K542_C0.6120.79
312_V316_E0.6110.79
264_F268_K0.6100.79
91_I226_H0.6090.79
311_Y316_E0.6090.79
293_E298_L0.6080.79
105_K427_A0.6080.79
128_H208_L0.6070.78
306_N317_S0.6070.78
98_L105_K0.6070.78
497_P547_W0.6050.78
452_V553_P0.6040.78
573_V581_A0.6030.78
146_D160_V0.6030.78
470_T479_A0.6030.78
342_C351_A0.6030.78
462_M602_I0.6030.78
97_T100_E0.6020.78
356_S360_T0.6010.78
56_E448_L0.6000.78
607_R611_D0.6000.78
373_V379_S0.5990.78
620_G623_N0.5980.77
345_L358_M0.5970.77
205_R210_L0.5960.77
341_L348_I0.5950.77
97_T545_H0.5940.77
335_K347_K0.5940.77
484_T614_S0.5930.77
60_M448_L0.5930.77
110_S113_A0.5930.77
317_S322_G0.5930.77
346_D353_V0.5920.77
299_I316_E0.5920.77
50_L425_S0.5910.77
293_E306_N0.5910.77
459_D636_V0.5910.77
463_S614_S0.5910.77
196_D200_C0.5910.77
126_K131_Y0.5900.76
299_I303_L0.5890.76
127_S456_Y0.5890.76
258_E604_R0.5890.76
332_H341_L0.5890.76
390_W572_P0.5880.76
288_Q292_R0.5870.76
316_E322_G0.5860.76
413_E417_S0.5850.76
160_V166_M0.5850.76
365_E375_Q0.5840.76
310_F318_K0.5840.76
521_E545_H0.5840.76
148_K151_D0.5840.76
572_P576_A0.5830.76
68_T455_P0.5830.76
95_D128_H0.5830.76
45_F450_L0.5820.76
436_D440_D0.5820.76
77_F80_S0.5810.75
227_D499_F0.5810.75
59_V447_Y0.5810.75
89_A221_L0.5800.75
374_E377_A0.5790.75
427_A456_Y0.5790.75
315_E318_K0.5790.75
161_H164_Q0.5770.75
426_S493_L0.5770.75
471_D476_Q0.5750.75
305_A317_S0.5750.75
577_K580_G0.5740.75
472_M476_Q0.5740.75
318_K322_G0.5730.74
128_H209_T0.5720.74
295_F317_S0.5720.74
211_S594_M0.5720.74
296_A299_I0.5710.74
210_L503_N0.5710.74
428_T607_R0.5710.74
366_L372_Y0.5690.74
120_I220_D0.5670.74
98_L545_H0.5670.74
54_F81_Y0.5670.74
298_L322_G0.5660.74
164_Q167_Q0.5660.74
80_S491_R0.5660.74
347_K351_A0.5650.73
75_L601_G0.5650.73
259_G499_F0.5650.73
74_Y95_D0.5640.73
375_Q378_Y0.5630.73
64_A77_F0.5630.73
333_R339_D0.5620.73
554_G608_S0.5620.73
295_F309_F0.5620.73
494_V561_T0.5610.73
306_N316_E0.5610.73
586_F591_L0.5600.73
471_D479_A0.5600.73
47_A51_E0.5590.73
46_M73_V0.5590.73
263_E267_Q0.5590.73
294_E299_I0.5590.73
98_L126_K0.5580.72
339_D346_D0.5580.72
517_P537_E0.5570.72
68_T454_S0.5570.72
292_R298_L0.5570.72
568_P578_R0.5560.72
308_E314_S0.5560.72
294_E314_S0.5560.72
37_F565_L0.5560.72
393_K398_S0.5550.72
96_E225_S0.5540.72
474_A477_K0.5540.72
304_L315_E0.5530.72
242_E245_L0.5530.72
586_F590_D0.5520.72
188_D192_D0.5520.72
258_E607_R0.5510.72
366_L370_E0.5510.72
293_E297_E0.5510.72
37_F44_V0.5500.71
316_E320_V0.5500.71
210_L214_Y0.5500.71
311_Y315_E0.5490.71
340_E348_I0.5480.71
61_F435_F0.5480.71
96_E526_I0.5480.71
183_N187_S0.5470.71
592_P629_E0.5470.71
226_H495_L0.5470.71
333_R341_L0.5470.71
66_V594_M0.5460.71
102_L223_I0.5460.71
606_I611_D0.5460.71
195_Q198_L0.5440.71
338_A344_L0.5420.70
370_E381_S0.5410.70
533_F541_L0.5410.70
294_E301_D0.5400.70
352_L358_M0.5400.70
577_K581_A0.5400.70
372_Y380_L0.5400.70
232_H249_P0.5390.70
258_E600_Q0.5380.70
139_K147_D0.5370.70
137_L167_Q0.5370.70
339_D353_V0.5370.70
505_F520_F0.5360.69
309_F319_E0.5350.69
314_S317_S0.5340.69
186_W190_S0.5340.69
49_Q53_A0.5330.69
137_L140_T0.5330.69
125_S228_F0.5320.69
343_R347_K0.5310.69
310_F321_A0.5300.69
492_T530_V0.5300.69
63_E101_Q0.5290.68
458_Y606_I0.5290.68
64_A68_T0.5290.68
266_A404_P0.5280.68
343_R352_L0.5280.68
82_A89_A0.5270.68
364_Y379_S0.5260.68
43_Q67_G0.5250.68
389_S393_K0.5240.68
482_I540_V0.5240.68
302_A307_D0.5240.68
97_T102_L0.5230.68
383_Y386_D0.5230.68
335_K342_C0.5220.67
54_F57_K0.5220.67
202_M205_R0.5220.67
95_D105_K0.5210.67
39_L47_A0.5200.67
306_N397_E0.5190.67
95_D566_P0.5180.67
263_E437_Y0.5170.67
470_T504_E0.5170.67
578_R589_V0.5170.67
54_F420_I0.5170.67
258_E603_G0.5170.67
404_P407_V0.5160.67
372_Y376_M0.5150.66
349_G353_V0.5150.66
345_L356_S0.5150.66
87_K617_I0.5150.66
229_Y247_L0.5130.66
300_E309_F0.5130.66
123_R215_Y0.5120.66
383_Y388_I0.5120.66
89_A98_L0.5100.66
40_R605_L0.5090.66
487_R612_S0.5090.66
315_E321_A0.5090.66
294_E311_Y0.5090.66
598_V622_E0.5080.65
338_A345_L0.5080.65
296_A305_A0.5070.65
551_D613_G0.5060.65
499_F557_L0.5050.65
426_S429_L0.5050.65
307_D314_S0.5040.65
181_L192_D0.5040.65
427_A521_E0.5040.65
363_Q367_S0.5040.65
68_T435_F0.5030.65
223_I387_A0.5030.65
334_V338_A0.5030.65
569_P581_A0.5020.64
514_L561_T0.5010.64
64_A225_S0.5010.64
334_V340_E0.5000.64
163_S170_Y0.5000.64
207_G210_L0.5000.64
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4a15A 1 0.8658 100 0.343 Contact Map
3crvA 1 0.8222 100 0.379 Contact Map
2vl7A 1 0.6833 100 0.43 Contact Map
1gkuB 1 0.5975 100 0.747 Contact Map
4ys0A 1 0.8268 100 0.766 Contact Map
3fhoA 2 0.4696 100 0.775 Contact Map
4dduA 1 0.6381 100 0.779 Contact Map
3oiyA 1 0.5819 100 0.787 Contact Map
4w7sA 2 0.6022 100 0.792 Contact Map
1xtiA 1 0.5663 100 0.796 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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