YPVA - BACSU - GREMLIN Contacts

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YPVA - Probable ATP-dependent helicase YpvA

UniProt:	P50831	Sequences: MTTSRLPFSLTKTKNFYEELNNWIGDVFYDILPEKGFDLRDEQVFMAFQLERAFKEKKVMFAEAGVGTGKTLVYLLFAISYARYVGKPAIIACADETLIEQLVKKEGDISKLAEHLDLKIDTRLSKSHEQYLCLKKLEKTMQRSDDDKWLDLYESLPSFVHESQAMQRFYPYGDRKQYANLSNEEWSDVSYDSFQDCLTCDMRHRCGLTLSRDYYRKSTDLIICSHDFYMEHVWTEESRKREGQLPLLPDHSAVVFDEGHLLEFAAQKALTYRVKQSTLELFLERLLQNDIREEFAELIEDALLANDEFFYVLSEESKEVAGSHRLEIKNDHRVKKAADELCRLLDKIGEALVFESEMYTIDQYELSVVEEYVEQMAYSLSLYQKDAISWLEKKEAESTFVVMPRTVAEVLGEKVFSKKIPYIFSSATLSEGGSFDYIADSLGIHDYLSLTVDSPYDYDEQMSINLYAKTDMDAEQKTAETIETIKRYKGRTLVLFPSFEELNEFKELSAAWELPYPIFFEGDEEISSLVEKFQEEEETVLCSVHLWEGLDIPGDALKNVTIWSLPFPPHDPVFTAKRNGAKKDPFEEVDLPYMLLRVRQGIGRLIRSNQDSGSIHIYAGGENERIIDEVKKVLPVEPHMM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	641 (574)
Sequences:	4177 (3137)
Seq/√Len:	130.9

ECOLI - DING YOAA
BACSU - YPVA DING
HALSA - Q9HMP9 Q9HQ08 Q9HMM1
SULSO - Q980I2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
457_D	460_E	6.359	1.00
78_A	255_V	4.362	1.00
476_Q	508_L	4.279	1.00
496_F	505_F	4.274	1.00
259_G	424_F	4.245	1.00
229_Y	256_F	4.004	1.00
509_S	542_C	3.915	1.00
485_I	492_T	3.784	1.00
54_F	253_A	3.566	1.00
41_D	45_F	3.392	1.00
482_I	561_T	3.333	1.00
496_F	542_C	3.286	1.00
46_M	62_A	3.269	1.00
488_Y	492_T	3.026	1.00
38_D	609_N	2.834	1.00
439_A	449_S	2.800	1.00
491_R	558_K	2.780	1.00
109_I	122_T	2.670	1.00
484_T	616_H	2.652	1.00
605_L	613_G	2.642	1.00
519_F	539_T	2.621	1.00
53_A	60_M	2.600	1.00
166_M	170_Y	2.568	1.00
499_F	544_V	2.562	1.00
506_K	520_F	2.541	1.00
58_K	448_L	2.471	1.00
617_I	622_E	2.462	1.00
98_L	101_Q	2.444	1.00
49_Q	450_L	2.425	1.00
172_Y	177_Q	2.362	1.00
340_E	343_R	2.343	1.00
46_M	425_S	2.324	1.00
411_L	416_F	2.321	1.00
482_I	494_V	2.309	1.00
303_L	307_D	2.302	1.00
547_W	601_G	2.297	1.00
175_R	186_W	2.287	1.00
531_E	535_E	2.282	1.00
78_A	89_A	2.276	1.00
71_T	102_L	2.269	1.00
100_E	104_K	2.260	1.00
123_R	219_T	2.230	1.00
412_G	417_S	2.159	1.00
42_E	452_V	2.147	1.00
500_E	504_E	2.117	1.00
602_I	615_I	2.098	1.00
52_R	56_E	2.072	1.00
310_F	314_S	2.056	1.00
484_T	559_N	2.028	1.00
416_F	424_F	2.027	1.00
559_N	616_H	2.024	1.00
256_F	262_L	2.018	1.00
553_P	608_S	1.991	1.00
480_E	512_W	1.982	1.00
492_T	559_N	1.976	1.00
307_D	310_F	1.974	1.00
261_L	548_E	1.969	1.00
479_A	508_L	1.966	1.00
166_M	169_F	1.953	1.00
475_E	479_A	1.928	1.00
34_E	37_F	1.925	1.00
367_S	371_E	1.907	1.00
481_T	618_Y	1.907	1.00
490_G	555_D	1.906	1.00
579_N	582_K	1.904	1.00
598_V	617_I	1.901	1.00
430_S	451_T	1.893	1.00
368_V	371_E	1.873	1.00
44_V	48_F	1.851	1.00
536_E	539_T	1.841	1.00
491_R	516_Y	1.840	1.00
303_L	309_F	1.818	1.00
595_L	630_V	1.812	1.00
197_C	200_C	1.803	1.00
53_A	58_K	1.792	1.00
485_I	540_V	1.783	1.00
582_K	585_P	1.780	1.00
273_R	401_V	1.774	1.00
517_P	532_K	1.769	1.00
61_F	439_A	1.764	1.00
102_L	105_K	1.752	1.00
555_D	558_K	1.744	1.00
496_F	502_L	1.741	1.00
561_T	618_Y	1.739	1.00
92_A	226_H	1.734	1.00
54_F	423_I	1.729	1.00
99_I	103_V	1.728	1.00
109_I	113_A	1.720	1.00
273_R	399_T	1.695	1.00
538_E	556_A	1.695	1.00
295_F	298_L	1.684	1.00
438_I	442_L	1.664	1.00
61_F	438_I	1.633	1.00
502_L	520_F	1.629	1.00
74_Y	425_S	1.629	1.00
435_F	449_S	1.609	1.00
371_E	375_Q	1.603	1.00
337_A	345_L	1.582	1.00
579_N	583_K	1.580	1.00
303_L	310_F	1.574	1.00
133_C	206_C	1.565	1.00
502_L	542_C	1.560	1.00
346_D	349_G	1.556	1.00
306_N	309_F	1.552	1.00
517_P	536_E	1.548	1.00
147_D	150_L	1.542	1.00
53_A	421_P	1.534	1.00
57_K	420_I	1.529	1.00
73_V	77_F	1.515	1.00
310_F	317_S	1.513	1.00
370_E	375_Q	1.513	1.00
578_R	590_D	1.512	1.00
134_L	137_L	1.512	1.00
488_Y	559_N	1.510	1.00
125_S	215_Y	1.510	1.00
528_S	531_E	1.502	1.00
489_K	516_Y	1.500	1.00
368_V	372_Y	1.494	1.00
419_K	422_Y	1.491	1.00
181_L	184_E	1.485	1.00
519_F	536_E	1.484	1.00
310_F	313_L	1.483	1.00
510_A	523_D	1.470	1.00
602_I	617_I	1.469	1.00
537_E	555_D	1.468	1.00
560_V	605_L	1.465	1.00
305_A	309_F	1.464	1.00
98_L	102_L	1.463	1.00
598_V	630_V	1.460	1.00
578_R	582_K	1.451	1.00
125_S	222_I	1.448	1.00
49_Q	448_L	1.448	1.00
534_Q	556_A	1.426	1.00
50_L	77_F	1.419	1.00
309_F	312_V	1.419	1.00
439_A	447_Y	1.417	1.00
299_I	302_A	1.407	1.00
474_A	478_T	1.404	1.00
307_D	311_Y	1.403	1.00
479_A	505_F	1.402	1.00
483_E	486_K	1.401	1.00
99_I	105_K	1.399	1.00
299_I	306_N	1.398	1.00
339_D	343_R	1.395	1.00
499_F	502_L	1.395	1.00
50_L	423_I	1.387	1.00
565_L	594_M	1.387	1.00
527_S	531_E	1.382	1.00
477_K	480_E	1.378	1.00
375_Q	379_S	1.378	1.00
99_I	104_K	1.378	1.00
343_R	346_D	1.377	1.00
99_I	102_L	1.374	1.00
350_E	353_V	1.372	1.00
558_K	612_S	1.372	1.00
302_A	306_N	1.371	1.00
562_I	615_I	1.368	1.00
494_V	540_V	1.358	1.00
306_N	320_V	1.348	1.00
316_E	319_E	1.345	1.00
90_I	251_H	1.339	1.00
484_T	561_T	1.338	1.00
254_V	422_Y	1.335	1.00
587_E	625_R	1.334	1.00
93_C	99_I	1.332	1.00
133_C	200_C	1.332	1.00
308_E	311_Y	1.329	1.00
90_I	254_V	1.316	1.00
101_Q	104_K	1.313	1.00
254_V	419_K	1.312	1.00
166_M	172_Y	1.311	1.00
552_I	556_A	1.308	1.00
337_A	344_L	1.298	1.00
149_W	152_L	1.297	1.00
365_E	368_V	1.294	1.00
310_F	316_E	1.294	1.00
581_A	589_V	1.290	1.00
372_Y	375_Q	1.287	1.00
491_R	537_E	1.287	1.00
98_L	103_V	1.284	1.00
562_I	602_I	1.282	1.00
124_L	223_I	1.279	1.00
519_F	532_K	1.279	1.00
46_M	50_L	1.276	1.00
584_D	587_E	1.273	1.00
367_S	370_E	1.272	1.00
575_T	578_R	1.265	1.00
120_I	221_L	1.256	1.00
587_E	591_L	1.255	1.00
263_E	441_S	1.254	1.00
499_F	503_N	1.254	1.00
366_L	369_V	1.249	1.00
170_Y	173_G	1.248	1.00
312_V	315_E	1.243	1.00
412_G	445_H	1.243	1.00
532_K	535_E	1.240	1.00
126_K	174_D	1.239	1.00
306_N	310_F	1.238	1.00
306_N	311_Y	1.236	1.00
303_L	311_Y	1.225	1.00
60_M	423_I	1.221	1.00
146_D	150_L	1.221	1.00
479_A	482_I	1.217	1.00
303_L	313_L	1.215	1.00
302_A	310_F	1.213	1.00
567_F	626_I	1.206	0.99
181_L	186_W	1.206	0.99
45_F	48_F	1.204	0.99
497_P	564_S	1.202	0.99
476_Q	480_E	1.200	0.99
166_M	173_G	1.199	0.99
61_F	442_L	1.190	0.99
314_S	319_E	1.185	0.99
89_A	255_V	1.181	0.99
368_V	373_V	1.176	0.99
344_L	348_I	1.176	0.99
61_F	429_L	1.176	0.99
493_L	543_S	1.176	0.99
213_D	217_K	1.174	0.99
299_I	310_F	1.167	0.99
348_I	352_L	1.164	0.99
529_L	541_L	1.162	0.99
96_E	130_Q	1.161	0.99
121_D	220_D	1.158	0.99
373_V	377_A	1.158	0.99
101_Q	105_K	1.155	0.99
229_Y	254_V	1.151	0.99
338_A	343_R	1.145	0.99
470_T	473_D	1.138	0.99
300_E	304_L	1.136	0.99
369_V	372_Y	1.134	0.99
528_S	532_K	1.131	0.99
49_Q	60_M	1.130	0.99
480_E	483_E	1.127	0.99
63_E	451_T	1.124	0.99
569_P	577_K	1.124	0.99
294_E	298_L	1.120	0.99
198_L	201_D	1.119	0.99
370_E	374_E	1.117	0.99
567_F	591_L	1.114	0.99
109_I	223_I	1.107	0.99
146_D	149_W	1.102	0.99
298_L	301_D	1.098	0.99
574_F	578_R	1.093	0.99
87_K	252_S	1.092	0.99
230_M	266_A	1.092	0.99
317_S	320_V	1.088	0.99
349_G	352_L	1.088	0.99
65_G	452_V	1.087	0.99
526_I	545_H	1.086	0.99
299_I	319_E	1.085	0.99
503_N	507_E	1.084	0.99
97_T	101_Q	1.080	0.99
478_T	481_T	1.077	0.99
368_V	375_Q	1.076	0.99
253_A	421_P	1.075	0.99
319_E	322_G	1.074	0.99
91_I	102_L	1.071	0.99
105_K	111_K	1.071	0.99
299_I	312_V	1.062	0.99
424_F	438_I	1.061	0.99
461_Q	606_I	1.059	0.99
506_K	510_A	1.058	0.99
365_E	371_E	1.056	0.99
569_P	573_V	1.055	0.99
604_R	607_R	1.054	0.99
94_A	265_A	1.047	0.99
302_A	309_F	1.045	0.99
339_D	344_L	1.045	0.99
475_E	505_F	1.045	0.99
455_P	554_G	1.044	0.99
264_F	593_Y	1.040	0.98
42_E	453_D	1.037	0.98
336_K	339_D	1.037	0.98
526_I	546_L	1.035	0.98
230_M	262_L	1.031	0.98
267_Q	577_K	1.031	0.98
132_L	206_C	1.031	0.98
474_A	481_T	1.019	0.98
337_A	340_E	1.019	0.98
508_L	512_W	1.019	0.98
504_E	507_E	1.016	0.98
296_A	300_E	1.014	0.98
495_L	547_W	1.012	0.98
503_N	523_D	1.012	0.98
62_A	452_V	1.012	0.98
401_V	573_V	1.007	0.98
557_L	605_L	1.006	0.98
99_I	225_S	1.006	0.98
522_G	525_E	1.006	0.98
103_V	223_I	1.000	0.98
298_L	303_L	1.000	0.98
351_A	355_E	0.995	0.98
430_S	435_F	0.995	0.98
79_I	221_L	0.992	0.98
345_L	348_I	0.992	0.98
339_D	342_C	0.991	0.98
603_G	607_R	0.990	0.98
624_E	627_I	0.985	0.98
298_L	320_V	0.984	0.98
576_A	579_N	0.983	0.98
574_F	589_V	0.981	0.98
332_H	336_K	0.979	0.98
305_A	308_E	0.974	0.98
133_C	197_C	0.974	0.98
71_T	256_F	0.961	0.97
307_D	315_E	0.960	0.97
149_W	173_G	0.958	0.97
520_F	523_D	0.956	0.97
125_S	224_C	0.953	0.97
469_K	481_T	0.952	0.97
186_W	189_V	0.950	0.97
200_C	206_C	0.949	0.97
343_R	350_E	0.949	0.97
503_N	520_F	0.947	0.97
303_L	312_V	0.947	0.97
575_T	579_N	0.941	0.97
559_N	614_S	0.940	0.97
337_A	347_K	0.937	0.97
79_I	120_I	0.936	0.97
370_E	376_M	0.928	0.97
83_R	220_D	0.925	0.97
344_L	349_G	0.924	0.97
306_N	312_V	0.922	0.97
338_A	342_C	0.921	0.97
561_T	616_H	0.920	0.97
378_Y	381_S	0.919	0.97
303_L	317_S	0.919	0.97
537_E	556_A	0.919	0.97
359_Y	362_D	0.918	0.97
309_F	317_S	0.915	0.97
293_E	296_A	0.914	0.97
311_Y	314_S	0.912	0.97
518_I	542_C	0.911	0.96
305_A	310_F	0.911	0.96
132_L	137_L	0.910	0.96
49_Q	452_V	0.910	0.96
456_Y	461_Q	0.909	0.96
441_S	577_K	0.909	0.96
59_V	62_A	0.908	0.96
341_L	344_L	0.907	0.96
40_R	64_A	0.907	0.96
180_N	184_E	0.906	0.96
310_F	320_V	0.904	0.96
92_A	229_Y	0.901	0.96
334_V	341_L	0.899	0.96
573_V	577_K	0.898	0.96
314_S	318_K	0.898	0.96
483_E	487_R	0.896	0.96
49_Q	52_R	0.895	0.96
96_E	99_I	0.895	0.96
54_F	421_P	0.895	0.96
134_L	138_E	0.895	0.96
40_R	43_Q	0.895	0.96
294_E	315_E	0.891	0.96
71_T	75_L	0.891	0.96
570_H	575_T	0.891	0.96
296_A	302_A	0.889	0.96
93_C	225_S	0.888	0.96
314_S	322_G	0.888	0.96
100_E	103_V	0.887	0.96
466_L	481_T	0.881	0.96
470_T	475_E	0.881	0.96
140_T	145_D	0.880	0.96
113_A	120_I	0.873	0.96
59_V	421_P	0.871	0.95
134_L	207_G	0.870	0.95
522_G	529_L	0.870	0.95
374_E	381_S	0.865	0.95
200_C	203_R	0.861	0.95
301_D	318_K	0.859	0.95
276_Q	280_E	0.859	0.95
180_N	183_N	0.859	0.95
365_E	370_E	0.858	0.95
100_E	527_S	0.858	0.95
340_E	344_L	0.857	0.95
478_T	482_I	0.855	0.95
475_E	478_T	0.854	0.95
94_A	261_L	0.854	0.95
224_C	229_Y	0.854	0.95
493_L	601_G	0.851	0.95
596_L	599_R	0.850	0.95
256_F	424_F	0.849	0.95
491_R	559_N	0.849	0.95
42_E	68_T	0.844	0.95
628_D	632_K	0.843	0.95
296_A	301_D	0.842	0.95
88_P	219_T	0.835	0.94
501_E	563_W	0.835	0.94
166_M	171_P	0.834	0.94
103_V	122_T	0.830	0.94
299_I	309_F	0.828	0.94
295_F	301_D	0.827	0.94
98_L	104_K	0.826	0.94
122_T	221_L	0.825	0.94
493_L	560_V	0.824	0.94
486_K	515_P	0.824	0.94
295_F	303_L	0.823	0.94
302_A	317_S	0.822	0.94
557_L	613_G	0.822	0.94
136_K	139_K	0.821	0.94
166_M	177_Q	0.820	0.94
111_K	114_E	0.819	0.94
569_P	572_P	0.818	0.94
54_F	78_A	0.818	0.94
600_Q	603_G	0.817	0.94
479_A	509_S	0.817	0.94
324_H	327_E	0.817	0.94
144_S	147_D	0.816	0.94
39_L	44_V	0.815	0.94
370_E	373_V	0.814	0.94
595_L	633_V	0.814	0.94
121_D	214_Y	0.813	0.93
48_F	52_R	0.813	0.93
500_E	503_N	0.813	0.93
505_F	508_L	0.811	0.93
317_S	321_A	0.811	0.93
504_E	508_L	0.811	0.93
589_V	593_Y	0.810	0.93
109_I	221_L	0.810	0.93
188_D	191_Y	0.804	0.93
65_G	454_S	0.801	0.93
478_T	618_Y	0.801	0.93
270_L	410_V	0.801	0.93
51_E	80_S	0.799	0.93
302_A	319_E	0.799	0.93
310_F	315_E	0.798	0.93
488_Y	558_K	0.796	0.93
338_A	346_D	0.795	0.93
295_F	300_E	0.792	0.93
371_E	374_E	0.791	0.93
224_C	228_F	0.790	0.92
595_L	629_E	0.790	0.92
305_A	312_V	0.790	0.92
46_M	452_V	0.787	0.92
494_V	542_C	0.785	0.92
276_Q	398_S	0.783	0.92
294_E	313_L	0.779	0.92
426_S	551_D	0.779	0.92
571_D	574_F	0.777	0.92
368_V	376_M	0.774	0.92
508_L	511_A	0.774	0.92
369_V	375_Q	0.774	0.92
53_A	59_V	0.773	0.92
275_K	399_T	0.773	0.92
392_E	401_V	0.772	0.92
295_F	308_E	0.771	0.92
530_V	552_I	0.770	0.91
74_Y	91_I	0.769	0.91
372_Y	379_S	0.769	0.91
295_F	314_S	0.767	0.91
337_A	342_C	0.767	0.91
574_F	590_D	0.767	0.91
383_Y	389_S	0.764	0.91
416_F	422_Y	0.764	0.91
94_A	98_L	0.762	0.91
474_A	479_A	0.762	0.91
75_L	102_L	0.762	0.91
471_D	475_E	0.762	0.91
103_V	124_L	0.761	0.91
65_G	455_P	0.758	0.91
544_V	547_W	0.757	0.91
351_A	357_E	0.756	0.91
300_E	303_L	0.756	0.91
569_P	575_T	0.755	0.91
82_A	86_G	0.755	0.91
260_H	426_S	0.755	0.91
123_R	211_S	0.753	0.91
128_H	232_H	0.752	0.91
505_F	542_C	0.750	0.90
411_L	442_L	0.745	0.90
295_F	310_F	0.743	0.90
51_E	55_K	0.742	0.90
547_W	599_R	0.742	0.90
569_P	574_F	0.741	0.90
353_V	357_E	0.741	0.90
338_A	348_I	0.741	0.90
63_E	430_S	0.739	0.90
145_D	149_W	0.738	0.90
125_S	211_S	0.737	0.90
568_P	593_Y	0.735	0.89
367_S	375_Q	0.735	0.89
367_S	373_V	0.735	0.89
139_K	144_S	0.735	0.89
113_A	117_D	0.735	0.89
347_K	357_E	0.735	0.89
295_F	305_A	0.734	0.89
309_F	315_E	0.729	0.89
303_L	308_E	0.729	0.89
141_M	146_D	0.727	0.89
570_H	586_F	0.725	0.89
267_Q	271_T	0.724	0.89
514_L	517_P	0.724	0.89
296_A	310_F	0.724	0.89
296_A	303_L	0.724	0.89
465_N	616_H	0.723	0.89
295_F	302_A	0.721	0.89
342_C	347_K	0.721	0.89
66_V	405_R	0.721	0.89
482_I	509_S	0.721	0.89
67_G	70_K	0.720	0.89
76_L	81_Y	0.720	0.89
466_L	469_K	0.720	0.89
506_K	518_I	0.718	0.88
304_L	308_E	0.718	0.88
299_I	313_L	0.718	0.88
591_L	625_R	0.717	0.88
174_D	177_Q	0.717	0.88
320_V	324_H	0.715	0.88
80_S	84_Y	0.714	0.88
76_L	80_S	0.714	0.88
567_F	586_F	0.712	0.88
507_E	510_A	0.708	0.88
337_A	341_L	0.708	0.88
162_E	166_M	0.707	0.88
301_D	313_L	0.705	0.87
348_I	351_A	0.705	0.87
562_I	598_V	0.704	0.87
572_P	575_T	0.704	0.87
622_E	631_K	0.704	0.87
486_K	514_L	0.703	0.87
296_A	313_L	0.703	0.87
190_S	193_S	0.702	0.87
304_L	310_F	0.702	0.87
163_S	166_M	0.701	0.87
263_E	438_I	0.700	0.87
298_L	309_F	0.700	0.87
531_E	534_Q	0.699	0.87
350_E	354_F	0.698	0.87
227_D	269_A	0.698	0.87
624_E	628_D	0.698	0.87
138_E	202_M	0.697	0.87
116_L	120_I	0.697	0.87
352_L	360_T	0.695	0.87
300_E	322_G	0.695	0.87
309_F	313_L	0.694	0.87
431_E	595_L	0.694	0.87
52_R	448_L	0.693	0.87
344_L	347_K	0.691	0.86
376_M	380_L	0.690	0.86
297_E	300_E	0.690	0.86
490_G	558_K	0.690	0.86
347_K	352_L	0.689	0.86
168_R	171_P	0.688	0.86
473_D	481_T	0.687	0.86
574_F	577_K	0.687	0.86
507_E	511_A	0.687	0.86
349_G	357_E	0.686	0.86
332_H	335_K	0.686	0.86
516_Y	521_E	0.685	0.86
376_M	381_S	0.685	0.86
135_K	201_D	0.684	0.86
294_E	322_G	0.684	0.86
61_F	444_I	0.682	0.86
183_N	193_S	0.681	0.86
600_Q	607_R	0.681	0.86
521_E	586_F	0.680	0.86
310_F	319_E	0.679	0.85
574_F	581_A	0.679	0.85
160_V	167_Q	0.677	0.85
127_S	225_S	0.676	0.85
337_A	346_D	0.676	0.85
464_I	617_I	0.674	0.85
265_A	268_K	0.674	0.85
351_A	358_M	0.674	0.85
600_Q	604_R	0.673	0.85
147_D	151_D	0.672	0.85
148_K	152_L	0.670	0.85
127_S	130_Q	0.669	0.85
372_Y	377_A	0.669	0.85
81_Y	253_A	0.668	0.85
275_K	278_T	0.668	0.85
141_M	164_Q	0.668	0.85
280_E	284_E	0.667	0.84
228_F	231_E	0.667	0.84
527_S	555_D	0.666	0.84
489_K	538_E	0.666	0.84
298_L	310_F	0.665	0.84
517_P	539_T	0.665	0.84
336_K	343_R	0.664	0.84
53_A	423_I	0.664	0.84
267_Q	403_M	0.664	0.84
96_E	101_Q	0.660	0.84
306_N	314_S	0.657	0.84
484_T	618_Y	0.656	0.83
197_C	206_C	0.654	0.83
453_D	632_K	0.654	0.83
78_A	253_A	0.652	0.83
365_E	379_S	0.651	0.83
493_L	552_I	0.649	0.83
366_L	377_A	0.649	0.83
472_M	481_T	0.648	0.83
525_E	528_S	0.647	0.83
94_A	97_T	0.644	0.82
595_L	598_V	0.643	0.82
350_E	357_E	0.643	0.82
296_A	325_R	0.642	0.82
140_T	148_K	0.642	0.82
320_V	323_S	0.640	0.82
207_G	564_S	0.640	0.82
128_H	191_Y	0.639	0.82
299_I	305_A	0.639	0.82
516_Y	540_V	0.638	0.82
228_F	232_H	0.638	0.82
74_Y	226_H	0.637	0.82
170_Y	177_Q	0.636	0.82
47_A	77_F	0.636	0.82
364_Y	372_Y	0.634	0.81
371_E	378_Y	0.634	0.81
333_R	336_K	0.634	0.81
62_A	450_L	0.634	0.81
387_A	402_V	0.633	0.81
226_H	232_H	0.632	0.81
126_K	130_Q	0.632	0.81
435_F	439_A	0.631	0.81
366_L	371_E	0.630	0.81
596_L	606_I	0.629	0.81
310_F	323_S	0.629	0.81
50_L	74_Y	0.628	0.81
533_F	539_T	0.627	0.81
182_S	185_E	0.626	0.81
336_K	340_E	0.626	0.81
371_E	376_M	0.626	0.81
161_H	165_A	0.624	0.80
93_C	98_L	0.622	0.80
126_K	225_S	0.622	0.80
306_N	313_L	0.621	0.80
214_Y	219_T	0.621	0.80
98_L	225_S	0.621	0.80
475_E	501_E	0.621	0.80
478_T	563_W	0.620	0.80
346_D	352_L	0.619	0.80
227_D	265_A	0.619	0.80
477_K	481_T	0.618	0.80
308_E	316_E	0.617	0.80
520_F	524_E	0.617	0.80
302_A	305_A	0.617	0.80
95_D	98_L	0.617	0.80
36_G	40_R	0.617	0.80
526_I	530_V	0.615	0.79
377_A	381_S	0.615	0.79
337_A	349_G	0.615	0.79
476_Q	504_E	0.615	0.79
72_L	76_L	0.615	0.79
208_L	212_R	0.613	0.79
506_K	542_C	0.612	0.79
312_V	316_E	0.611	0.79
264_F	268_K	0.610	0.79
91_I	226_H	0.609	0.79
311_Y	316_E	0.609	0.79
293_E	298_L	0.608	0.79
105_K	427_A	0.608	0.79
128_H	208_L	0.607	0.78
306_N	317_S	0.607	0.78
98_L	105_K	0.607	0.78
497_P	547_W	0.605	0.78
452_V	553_P	0.604	0.78
573_V	581_A	0.603	0.78
146_D	160_V	0.603	0.78
470_T	479_A	0.603	0.78
342_C	351_A	0.603	0.78
462_M	602_I	0.603	0.78
97_T	100_E	0.602	0.78
356_S	360_T	0.601	0.78
56_E	448_L	0.600	0.78
607_R	611_D	0.600	0.78
373_V	379_S	0.599	0.78
620_G	623_N	0.598	0.77
345_L	358_M	0.597	0.77
205_R	210_L	0.596	0.77
341_L	348_I	0.595	0.77
97_T	545_H	0.594	0.77
335_K	347_K	0.594	0.77
484_T	614_S	0.593	0.77
60_M	448_L	0.593	0.77
110_S	113_A	0.593	0.77
317_S	322_G	0.593	0.77
346_D	353_V	0.592	0.77
299_I	316_E	0.592	0.77
50_L	425_S	0.591	0.77
293_E	306_N	0.591	0.77
459_D	636_V	0.591	0.77
463_S	614_S	0.591	0.77
196_D	200_C	0.591	0.77
126_K	131_Y	0.590	0.76
299_I	303_L	0.589	0.76
127_S	456_Y	0.589	0.76
258_E	604_R	0.589	0.76
332_H	341_L	0.589	0.76
390_W	572_P	0.588	0.76
288_Q	292_R	0.587	0.76
316_E	322_G	0.586	0.76
413_E	417_S	0.585	0.76
160_V	166_M	0.585	0.76
365_E	375_Q	0.584	0.76
310_F	318_K	0.584	0.76
521_E	545_H	0.584	0.76
148_K	151_D	0.584	0.76
572_P	576_A	0.583	0.76
68_T	455_P	0.583	0.76
95_D	128_H	0.583	0.76
45_F	450_L	0.582	0.76
436_D	440_D	0.582	0.76
77_F	80_S	0.581	0.75
227_D	499_F	0.581	0.75
59_V	447_Y	0.581	0.75
89_A	221_L	0.580	0.75
374_E	377_A	0.579	0.75
427_A	456_Y	0.579	0.75
315_E	318_K	0.579	0.75
161_H	164_Q	0.577	0.75
426_S	493_L	0.577	0.75
471_D	476_Q	0.575	0.75
305_A	317_S	0.575	0.75
577_K	580_G	0.574	0.75
472_M	476_Q	0.574	0.75
318_K	322_G	0.573	0.74
128_H	209_T	0.572	0.74
295_F	317_S	0.572	0.74
211_S	594_M	0.572	0.74
296_A	299_I	0.571	0.74
210_L	503_N	0.571	0.74
428_T	607_R	0.571	0.74
366_L	372_Y	0.569	0.74
120_I	220_D	0.567	0.74
98_L	545_H	0.567	0.74
54_F	81_Y	0.567	0.74
298_L	322_G	0.566	0.74
164_Q	167_Q	0.566	0.74
80_S	491_R	0.566	0.74
347_K	351_A	0.565	0.73
75_L	601_G	0.565	0.73
259_G	499_F	0.565	0.73
74_Y	95_D	0.564	0.73
375_Q	378_Y	0.563	0.73
64_A	77_F	0.563	0.73
333_R	339_D	0.562	0.73
554_G	608_S	0.562	0.73
295_F	309_F	0.562	0.73
494_V	561_T	0.561	0.73
306_N	316_E	0.561	0.73
586_F	591_L	0.560	0.73
471_D	479_A	0.560	0.73
47_A	51_E	0.559	0.73
46_M	73_V	0.559	0.73
263_E	267_Q	0.559	0.73
294_E	299_I	0.559	0.73
98_L	126_K	0.558	0.72
339_D	346_D	0.558	0.72
517_P	537_E	0.557	0.72
68_T	454_S	0.557	0.72
292_R	298_L	0.557	0.72
568_P	578_R	0.556	0.72
308_E	314_S	0.556	0.72
294_E	314_S	0.556	0.72
37_F	565_L	0.556	0.72
393_K	398_S	0.555	0.72
96_E	225_S	0.554	0.72
474_A	477_K	0.554	0.72
304_L	315_E	0.553	0.72
242_E	245_L	0.553	0.72
586_F	590_D	0.552	0.72
188_D	192_D	0.552	0.72
258_E	607_R	0.551	0.72
366_L	370_E	0.551	0.72
293_E	297_E	0.551	0.72
37_F	44_V	0.550	0.71
316_E	320_V	0.550	0.71
210_L	214_Y	0.550	0.71
311_Y	315_E	0.549	0.71
340_E	348_I	0.548	0.71
61_F	435_F	0.548	0.71
96_E	526_I	0.548	0.71
183_N	187_S	0.547	0.71
592_P	629_E	0.547	0.71
226_H	495_L	0.547	0.71
333_R	341_L	0.547	0.71
66_V	594_M	0.546	0.71
102_L	223_I	0.546	0.71
606_I	611_D	0.546	0.71
195_Q	198_L	0.544	0.71
338_A	344_L	0.542	0.70
370_E	381_S	0.541	0.70
533_F	541_L	0.541	0.70
294_E	301_D	0.540	0.70
352_L	358_M	0.540	0.70
577_K	581_A	0.540	0.70
372_Y	380_L	0.540	0.70
232_H	249_P	0.539	0.70
258_E	600_Q	0.538	0.70
139_K	147_D	0.537	0.70
137_L	167_Q	0.537	0.70
339_D	353_V	0.537	0.70
505_F	520_F	0.536	0.69
309_F	319_E	0.535	0.69
314_S	317_S	0.534	0.69
186_W	190_S	0.534	0.69
49_Q	53_A	0.533	0.69
137_L	140_T	0.533	0.69
125_S	228_F	0.532	0.69
343_R	347_K	0.531	0.69
310_F	321_A	0.530	0.69
492_T	530_V	0.530	0.69
63_E	101_Q	0.529	0.68
458_Y	606_I	0.529	0.68
64_A	68_T	0.529	0.68
266_A	404_P	0.528	0.68
343_R	352_L	0.528	0.68
82_A	89_A	0.527	0.68
364_Y	379_S	0.526	0.68
43_Q	67_G	0.525	0.68
389_S	393_K	0.524	0.68
482_I	540_V	0.524	0.68
302_A	307_D	0.524	0.68
97_T	102_L	0.523	0.68
383_Y	386_D	0.523	0.68
335_K	342_C	0.522	0.67
54_F	57_K	0.522	0.67
202_M	205_R	0.522	0.67
95_D	105_K	0.521	0.67
39_L	47_A	0.520	0.67
306_N	397_E	0.519	0.67
95_D	566_P	0.518	0.67
263_E	437_Y	0.517	0.67
470_T	504_E	0.517	0.67
578_R	589_V	0.517	0.67
54_F	420_I	0.517	0.67
258_E	603_G	0.517	0.67
404_P	407_V	0.516	0.67
372_Y	376_M	0.515	0.66
349_G	353_V	0.515	0.66
345_L	356_S	0.515	0.66
87_K	617_I	0.515	0.66
229_Y	247_L	0.513	0.66
300_E	309_F	0.513	0.66
123_R	215_Y	0.512	0.66
383_Y	388_I	0.512	0.66
89_A	98_L	0.510	0.66
40_R	605_L	0.509	0.66
487_R	612_S	0.509	0.66
315_E	321_A	0.509	0.66
294_E	311_Y	0.509	0.66
598_V	622_E	0.508	0.65
338_A	345_L	0.508	0.65
296_A	305_A	0.507	0.65
551_D	613_G	0.506	0.65
499_F	557_L	0.505	0.65
426_S	429_L	0.505	0.65
307_D	314_S	0.504	0.65
181_L	192_D	0.504	0.65
427_A	521_E	0.504	0.65
363_Q	367_S	0.504	0.65
68_T	435_F	0.503	0.65
223_I	387_A	0.503	0.65
334_V	338_A	0.503	0.65
569_P	581_A	0.502	0.64
514_L	561_T	0.501	0.64
64_A	225_S	0.501	0.64
334_V	340_E	0.500	0.64
163_S	170_Y	0.500	0.64
207_G	210_L	0.500	0.64

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4a15A	1	0.8658	100	0.343	Contact Map
3crvA	1	0.8222	100	0.379	Contact Map
2vl7A	1	0.6833	100	0.43	Contact Map
1gkuB	1	0.5975	100	0.747	Contact Map
4ys0A	1	0.8268	100	0.766	Contact Map
3fhoA	2	0.4696	100	0.775	Contact Map
4dduA	1	0.6381	100	0.779	Contact Map
3oiyA	1	0.5819	100	0.787	Contact Map
4w7sA	2	0.6022	100	0.792	Contact Map
1xtiA	1	0.5663	100	0.796	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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