YPRA - BACSU - GREMLIN Contacts

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YPRA - Uncharacterized ATP-dependent helicase YprA

UniProt:	P50830	Sequences: MKKKSLTELISDLKGNENVVNWHEIEPREAKTRPMPESIDERIKAALSKRGIDELYTHQYSAFQYVQKGESIVTVTPTASGKTLCYNLPVLQSIAQDETNRALYLFPTKALAQDQKSELNEIIDEMGIDIKSFTYDGDTSPAIRQKVRKAGHIVITNPDMLHSAILPHHTKWVSLFENLKYIVIDELHTYRGVFGSHVANVIRRLKRICRFYGSDPVFICTSATIANPKELGEQLTGKPMRLVDDNGAPSGRKHFVFYNPPIVNKPLNIRRSATAEVNELAKEFLKNKVQTIVFARSRVRVEIILSHIQELVKKEIGTKSIRGYRGGYLPKERREIERGLREGDILGVVSTNALELGVDIGQLQVCVMTGYPGSVASAWQQAGRAGRRHGESLIIMVANSTPIDQYIVRHPEYFFNRSPESARINPENLIILVDHLKCAAYELPFRADEEFGAMEVSDILEYLQEEAVLHRNGERYHWASESFPASNISLRSASQENVVIVDQSDIANVRIIGEMDRFSAMTLLHDEAIYLHEGVQYQVEKLDWDHKKAYVRKVDVEYYTDANLAVQLKVLEIDKTKEKSRTSLHYGDVTVNALPTIFKKIKMTTFENIGSGPIHLPEEELHTSAAWLEIKTADEDIGEKTLEQLLLGISNVLQHIVPVYIMCDRNDVHVVSQIKAAHTGLPTIFLYDHYPGGIGLAEEVFKRFSDINEAAKQLITHCPCHDGCPSCIGTEIEGIKAKERILQLLDQMS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	749 (684)
Sequences:	2327 (1784)
Seq/√Len:	68.2

BACSU - YPRA
HALSA - Q9HQA5
SULSO - Q981C8 HELX Q980C0 Q97ZF3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
234_Q	237_G	5.528	1.00
231_L	236_T	5.201	1.00
57_T	247_G	4.514	1.00
92_Q	96_Q	4.425	1.00
339_G	344_D	4.409	1.00
712_K	716_T	4.391	1.00
90_V	102_A	4.354	1.00
539_V	551_V	4.121	1.00
93_S	180_K	4.029	1.00
231_L	237_G	3.765	1.00
232_G	236_T	3.670	1.00
703_R	706_D	3.559	1.00
71_S	238_K	3.467	1.00
70_E	241_R	3.453	1.00
74_T	85_C	3.259	1.00
382_A	394_I	3.228	1.00
484_P	488_I	3.216	1.00
335_E	339_G	3.180	1.00
271_R	276_E	3.137	1.00
231_L	234_Q	3.109	1.00
540_E	552_R	3.079	1.00
187_L	220_C	3.050	1.00
398_A	408_V	3.031	1.00
184_I	202_I	3.010	1.00
243_V	247_G	3.000	1.00
206_K	218_F	2.995	1.00
284_F	365_V	2.873	1.00
232_G	237_G	2.870	1.00
182_I	218_F	2.826	1.00
239_P	243_V	2.803	1.00
105_L	156_T	2.724	1.00
230_E	236_T	2.723	1.00
230_E	237_G	2.704	1.00
566_V	570_V	2.663	1.00
566_V	569_K	2.604	1.00
366_C	385_A	2.602	1.00
231_L	235_L	2.587	1.00
206_K	238_K	2.558	1.00
270_R	276_E	2.550	1.00
40_D	92_Q	2.531	1.00
87_N	104_Y	2.512	1.00
86_Y	106_F	2.481	1.00
230_E	234_Q	2.479	1.00
647_L	651_N	2.479	1.00
90_V	183_V	2.452	1.00
57_T	61_S	2.408	1.00
320_S	346_L	2.398	1.00
233_E	237_G	2.385	1.00
295_A	301_V	2.346	1.00
44_K	48_S	2.345	1.00
101_R	152_H	2.316	1.00
65_Y	243_V	2.300	1.00
352_N	381_Q	2.271	1.00
293_V	367_V	2.249	1.00
66_V	72_I	2.238	1.00
69_G	217_V	2.208	1.00
66_V	219_I	2.173	1.00
571_L	574_D	2.168	1.00
713_Q	717_H	2.158	1.00
277_V	284_F	2.154	1.00
338_R	342_E	2.147	1.00
589_V	625_A	2.136	1.00
699_E	703_R	2.065	1.00
236_T	243_V	2.065	1.00
109_K	157_N	2.062	1.00
233_E	236_T	2.060	1.00
301_V	305_L	2.033	1.00
676_A	679_T	1.998	1.00
182_I	206_K	1.991	1.00
450_E	454_M	1.986	1.00
196_S	424_I	1.977	1.00
67_Q	92_Q	1.968	1.00
599_K	602_K	1.953	1.00
705_S	709_E	1.948	1.00
244_D	247_G	1.944	1.00
647_L	733_E	1.936	1.00
229_K	233_E	1.906	1.00
83_T	87_N	1.898	1.00
41_E	45_A	1.895	1.00
236_T	240_M	1.894	1.00
295_A	349_V	1.855	1.00
710_A	713_Q	1.851	1.00
460_L	464_Q	1.847	1.00
133_F	147_V	1.845	1.00
704_F	708_N	1.843	1.00
60_Y	64_Q	1.842	1.00
253_K	256_V	1.842	1.00
240_M	247_G	1.826	1.00
587_G	627_W	1.821	1.00
229_K	242_L	1.821	1.00
595_P	599_K	1.820	1.00
281_A	293_V	1.815	1.00
210_R	215_D	1.812	1.00
713_Q	716_T	1.804	1.00
94_I	152_H	1.789	1.00
650_S	654_Q	1.789	1.00
723_G	729_G	1.784	1.00
243_V	246_N	1.772	1.00
93_S	181_Y	1.763	1.00
87_N	119_L	1.741	1.00
448_D	452_G	1.739	1.00
515_M	524_L	1.738	1.00
242_L	246_N	1.725	1.00
591_V	598_F	1.712	1.00
76_T	80_S	1.704	1.00
570_V	573_I	1.701	1.00
720_C	727_C	1.700	1.00
292_I	366_C	1.699	1.00
333_R	337_E	1.699	1.00
72_I	243_V	1.674	0.99
724_C	727_C	1.674	0.99
201_V	490_L	1.652	0.99
478_W	483_F	1.648	0.99
451_F	454_M	1.642	0.99
324_Y	337_E	1.634	0.99
119_L	153_I	1.630	0.99
461_E	464_Q	1.628	0.99
490_L	495_Q	1.621	0.99
230_E	235_L	1.603	0.99
709_E	713_Q	1.602	0.99
116_K	120_N	1.599	0.99
40_D	43_I	1.563	0.99
484_P	487_N	1.558	0.99
485_A	491_R	1.554	0.99
188_H	380_Q	1.549	0.99
135_Y	160_M	1.544	0.99
242_L	247_G	1.544	0.99
598_F	601_I	1.530	0.99
277_V	397_V	1.521	0.99
143_I	146_K	1.520	0.99
71_S	217_V	1.518	0.99
650_S	670_V	1.509	0.99
65_Y	72_I	1.508	0.99
72_I	217_V	1.508	0.99
108_T	159_D	1.500	0.99
86_Y	221_T	1.483	0.99
462_Y	466_E	1.480	0.99
58_H	76_T	1.479	0.99
481_E	484_P	1.477	0.99
557_E	560_T	1.473	0.99
579_K	582_T	1.472	0.99
85_C	89_P	1.471	0.99
211_F	443_L	1.469	0.99
329_L	332_E	1.463	0.99
63_F	88_L	1.462	0.99
65_Y	70_E	1.461	0.99
249_P	252_R	1.456	0.98
290_Q	346_L	1.454	0.98
283_E	286_K	1.444	0.98
720_C	724_C	1.443	0.98
237_G	243_V	1.438	0.98
340_L	348_V	1.430	0.98
595_P	600_K	1.429	0.98
240_M	243_V	1.424	0.98
700_V	707_I	1.418	0.98
39_I	44_K	1.417	0.98
156_T	161_L	1.417	0.98
486_S	492_S	1.412	0.98
457_S	461_E	1.411	0.98
303_I	307_H	1.407	0.98
84_L	118_E	1.406	0.98
654_Q	670_V	1.405	0.98
117_S	341_R	1.405	0.98
560_T	566_V	1.401	0.98
94_I	153_I	1.394	0.98
58_H	80_S	1.394	0.98
660_Y	706_D	1.394	0.98
252_R	255_F	1.390	0.98
278_N	282_K	1.372	0.98
368_M	382_A	1.363	0.98
439_A	442_E	1.363	0.98
45_A	48_S	1.363	0.98
651_N	733_E	1.360	0.98
563_N	568_L	1.360	0.98
199_A	203_R	1.358	0.98
476_Y	479_A	1.350	0.98
48_S	53_D	1.344	0.97
486_S	490_L	1.343	0.97
476_Y	482_S	1.342	0.97
577_K	580_S	1.333	0.97
93_S	100_N	1.332	0.97
220_C	236_T	1.328	0.97
62_A	85_C	1.327	0.97
368_M	381_Q	1.325	0.97
252_R	391_E	1.325	0.97
55_L	88_L	1.315	0.97
456_V	460_L	1.312	0.97
239_P	247_G	1.311	0.97
61_S	64_Q	1.309	0.97
189_T	356_L	1.307	0.97
473_G	480_S	1.307	0.97
599_K	603_M	1.304	0.97
651_N	654_Q	1.303	0.97
650_S	672_S	1.294	0.97
43_I	47_L	1.291	0.97
304_I	307_H	1.290	0.97
282_K	286_K	1.286	0.97
324_Y	353_A	1.283	0.97
524_L	530_Y	1.282	0.97
259_N	405_Q	1.279	0.97
322_R	533_E	1.267	0.96
484_P	491_R	1.266	0.96
276_E	279_E	1.263	0.96
78_T	111_L	1.260	0.96
618_E	624_S	1.258	0.96
117_S	121_E	1.255	0.96
109_K	136_D	1.243	0.96
271_R	275_A	1.241	0.96
471_R	474_E	1.238	0.96
307_H	310_E	1.237	0.96
563_N	566_V	1.235	0.96
277_V	281_A	1.235	0.96
324_Y	328_Y	1.228	0.96
616_L	620_E	1.227	0.96
476_Y	481_E	1.226	0.96
563_N	570_V	1.224	0.96
70_E	239_P	1.218	0.95
238_K	243_V	1.217	0.95
403_I	725_P	1.217	0.95
292_I	350_S	1.216	0.95
322_R	339_G	1.215	0.95
654_Q	672_S	1.210	0.95
627_W	631_K	1.210	0.95
109_K	138_D	1.209	0.95
596_T	599_K	1.209	0.95
269_I	272_S	1.205	0.95
474_E	477_H	1.203	0.95
304_I	311_L	1.202	0.95
296_R	381_Q	1.201	0.95
113_Q	136_D	1.200	0.95
649_I	652_V	1.195	0.95
679_T	682_P	1.192	0.95
269_I	273_A	1.190	0.95
562_A	572_E	1.177	0.95
531_L	536_Q	1.177	0.95
255_F	378_A	1.176	0.94
366_C	394_I	1.174	0.94
105_L	157_N	1.172	0.94
459_I	463_L	1.167	0.94
188_H	356_L	1.166	0.94
135_Y	164_A	1.164	0.94
156_T	160_M	1.160	0.94
698_E	702_K	1.158	0.94
605_T	610_G	1.142	0.94
660_Y	710_A	1.138	0.93
485_A	492_S	1.134	0.93
65_Y	241_R	1.131	0.93
731_E	734_G	1.130	0.93
569_K	573_I	1.116	0.93
589_V	595_P	1.113	0.93
101_R	174_S	1.113	0.93
478_W	481_E	1.112	0.93
87_N	118_E	1.103	0.92
139_T	144_R	1.103	0.92
249_P	253_K	1.100	0.92
305_L	323_G	1.099	0.92
306_S	309_Q	1.098	0.92
252_R	256_V	1.095	0.92
232_G	235_L	1.095	0.92
361_G	388_R	1.091	0.92
181_Y	219_I	1.090	0.92
476_Y	483_F	1.090	0.92
617_P	625_A	1.083	0.92
467_A	471_R	1.080	0.92
483_F	486_S	1.079	0.92
145_Q	149_K	1.079	0.92
479_A	482_S	1.076	0.91
428_N	435_H	1.070	0.91
209_C	214_S	1.069	0.91
253_K	259_N	1.068	0.91
562_A	565_A	1.067	0.91
498_V	502_D	1.066	0.91
97_D	180_K	1.065	0.91
39_I	47_L	1.063	0.91
38_S	41_E	1.063	0.91
65_Y	68_K	1.059	0.91
90_V	181_Y	1.058	0.91
182_I	202_I	1.057	0.91
456_V	462_Y	1.056	0.91
254_H	257_F	1.055	0.91
144_R	147_V	1.055	0.91
669_H	689_H	1.054	0.91
604_T	609_I	1.052	0.90
305_L	309_Q	1.052	0.90
576_T	580_S	1.051	0.90
498_V	501_V	1.046	0.90
97_D	101_R	1.046	0.90
588_D	622_H	1.046	0.90
590_T	620_E	1.046	0.90
184_I	198_V	1.043	0.90
562_A	566_V	1.038	0.90
242_L	245_D	1.035	0.90
378_A	396_M	1.032	0.90
364_Q	390_G	1.032	0.90
61_S	65_Y	1.031	0.90
689_H	732_I	1.031	0.90
290_Q	364_Q	1.029	0.89
565_A	570_V	1.029	0.89
38_S	67_Q	1.028	0.89
491_R	494_S	1.025	0.89
558_Y	566_V	1.022	0.89
595_P	602_K	1.022	0.89
679_T	683_T	1.022	0.89
85_C	123_I	1.019	0.89
64_Q	68_K	1.018	0.89
425_N	699_E	1.015	0.89
110_A	380_Q	1.015	0.89
303_I	531_L	1.015	0.89
55_L	63_F	1.013	0.89
647_L	650_S	1.013	0.89
61_S	241_R	1.013	0.89
595_P	610_G	1.013	0.89
723_G	733_E	1.007	0.88
528_A	598_F	1.006	0.88
599_K	608_N	1.006	0.88
670_V	689_H	1.004	0.88
725_P	733_E	1.001	0.88
145_Q	148_R	1.000	0.88
232_G	243_V	0.999	0.88
617_P	621_L	0.999	0.88
589_V	593_A	0.998	0.88
487_N	494_S	0.997	0.88
577_K	705_S	0.997	0.88
586_Y	624_S	0.994	0.88
233_E	239_P	0.993	0.88
578_E	581_R	0.992	0.88
569_K	590_T	0.991	0.88
526_D	541_K	0.990	0.88
78_T	223_A	0.983	0.87
111_L	115_Q	0.981	0.87
487_N	491_R	0.981	0.87
490_L	494_S	0.979	0.87
647_L	672_S	0.978	0.87
240_M	245_D	0.975	0.87
554_V	557_E	0.975	0.87
573_I	576_T	0.975	0.87
652_V	711_A	0.972	0.87
615_H	620_E	0.971	0.87
412_E	416_N	0.970	0.86
704_F	707_I	0.970	0.86
592_N	595_P	0.968	0.86
707_I	710_A	0.968	0.86
270_R	273_A	0.968	0.86
497_N	501_V	0.967	0.86
481_E	490_L	0.967	0.86
614_I	617_P	0.965	0.86
702_K	710_A	0.964	0.86
379_W	382_A	0.964	0.86
94_I	130_I	0.963	0.86
606_F	611_S	0.962	0.86
272_S	275_A	0.961	0.86
603_M	606_F	0.961	0.86
73_V	220_C	0.960	0.86
239_P	242_L	0.958	0.86
124_D	127_G	0.955	0.86
648_G	728_I	0.950	0.85
108_T	356_L	0.949	0.85
448_D	451_F	0.946	0.85
704_F	714_L	0.944	0.85
159_D	194_F	0.943	0.85
524_L	549_A	0.943	0.85
702_K	706_D	0.943	0.85
355_E	380_Q	0.939	0.85
383_G	386_G	0.938	0.85
450_E	453_A	0.938	0.85
463_L	467_A	0.937	0.85
700_V	704_F	0.937	0.85
445_F	460_L	0.936	0.84
664_D	685_F	0.933	0.84
497_N	500_I	0.933	0.84
204_R	435_H	0.932	0.84
206_K	210_R	0.930	0.84
670_V	673_Q	0.929	0.84
115_Q	355_E	0.928	0.84
617_P	624_S	0.928	0.84
559_Y	566_V	0.927	0.84
708_N	712_K	0.925	0.84
280_L	367_V	0.922	0.84
568_L	573_I	0.918	0.83
479_A	486_S	0.918	0.83
302_E	305_L	0.918	0.83
479_A	484_P	0.917	0.83
478_W	484_P	0.914	0.83
280_L	284_F	0.914	0.83
111_L	359_D	0.912	0.83
111_L	372_P	0.909	0.83
192_G	355_E	0.909	0.83
475_R	478_W	0.907	0.83
437_K	442_E	0.906	0.82
670_V	734_G	0.906	0.82
479_A	487_N	0.903	0.82
456_V	459_I	0.903	0.82
654_Q	730_T	0.903	0.82
657_V	668_V	0.902	0.82
159_D	164_A	0.900	0.82
303_I	306_S	0.900	0.82
706_D	712_K	0.898	0.82
629_E	683_T	0.898	0.82
325_R	328_Y	0.897	0.82
502_D	508_N	0.896	0.82
279_E	286_K	0.896	0.82
78_T	383_G	0.895	0.82
268_N	277_V	0.895	0.82
614_I	618_E	0.894	0.82
488_I	491_R	0.894	0.82
599_K	611_S	0.890	0.81
74_T	221_T	0.890	0.81
368_M	378_A	0.889	0.81
560_T	564_L	0.889	0.81
550_Y	553_K	0.889	0.81
277_V	369_T	0.887	0.81
279_E	284_F	0.883	0.81
675_K	678_H	0.883	0.81
229_K	236_T	0.879	0.81
78_T	386_G	0.879	0.81
482_S	485_A	0.878	0.80
557_E	568_L	0.878	0.80
653_L	711_A	0.878	0.80
478_W	486_S	0.877	0.80
619_E	624_S	0.876	0.80
706_D	710_A	0.874	0.80
602_K	605_T	0.874	0.80
356_L	402_P	0.874	0.80
618_E	625_A	0.870	0.80
593_A	601_I	0.869	0.80
223_A	383_G	0.869	0.80
307_H	311_L	0.868	0.80
670_V	735_I	0.867	0.80
239_P	244_D	0.867	0.80
284_F	289_V	0.866	0.80
625_A	628_L	0.864	0.79
78_T	89_P	0.863	0.79
229_K	237_G	0.860	0.79
587_G	601_I	0.860	0.79
251_G	257_F	0.859	0.79
274_T	350_S	0.857	0.79
463_L	468_V	0.857	0.79
600_K	610_G	0.857	0.79
254_H	259_N	0.854	0.79
632_T	635_E	0.853	0.79
626_A	631_K	0.850	0.78
500_I	551_V	0.849	0.78
380_Q	384_R	0.845	0.78
149_K	210_R	0.844	0.78
568_L	671_V	0.844	0.78
103_L	182_I	0.843	0.78
490_L	493_A	0.842	0.78
365_V	395_I	0.841	0.78
86_Y	160_M	0.839	0.77
235_L	238_K	0.839	0.77
55_L	181_Y	0.839	0.77
110_A	114_D	0.837	0.77
529_I	538_Q	0.837	0.77
374_S	662_M	0.836	0.77
459_I	464_Q	0.835	0.77
62_A	221_T	0.835	0.77
543_D	560_T	0.835	0.77
435_H	438_C	0.834	0.77
588_D	592_N	0.833	0.77
592_N	598_F	0.832	0.77
597_I	611_S	0.832	0.77
479_A	495_Q	0.831	0.77
559_Y	568_L	0.831	0.77
272_S	276_E	0.830	0.77
486_S	493_A	0.829	0.77
657_V	700_V	0.829	0.77
525_H	532_H	0.827	0.76
655_H	658_P	0.825	0.76
719_P	726_S	0.822	0.76
273_A	277_V	0.822	0.76
191_R	664_D	0.822	0.76
111_L	114_D	0.821	0.76
67_Q	96_Q	0.821	0.76
435_H	440_A	0.821	0.76
712_K	715_I	0.820	0.76
520_A	524_L	0.819	0.76
703_R	712_K	0.819	0.76
597_I	603_M	0.819	0.76
699_E	702_K	0.818	0.76
482_S	493_A	0.815	0.75
552_R	556_V	0.815	0.75
706_D	709_E	0.815	0.75
520_A	523_L	0.813	0.75
666_N	732_I	0.811	0.75
461_E	471_R	0.810	0.75
101_R	178_N	0.810	0.75
414_F	417_R	0.810	0.75
428_N	440_A	0.810	0.75
106_F	115_Q	0.809	0.75
255_F	260_P	0.807	0.75
587_G	598_F	0.806	0.74
459_I	462_Y	0.806	0.74
278_N	286_K	0.805	0.74
153_I	182_I	0.804	0.74
485_A	489_S	0.804	0.74
73_V	187_L	0.804	0.74
114_D	353_A	0.803	0.74
597_I	601_I	0.803	0.74
255_F	259_N	0.800	0.74
367_V	397_V	0.800	0.74
725_P	734_G	0.799	0.74
151_G	381_Q	0.797	0.74
89_P	111_L	0.797	0.74
223_A	386_G	0.796	0.74
275_A	278_N	0.795	0.73
115_Q	192_G	0.795	0.73
593_A	596_T	0.794	0.73
552_R	557_E	0.793	0.73
732_I	735_I	0.793	0.73
590_T	622_H	0.791	0.73
500_I	504_S	0.791	0.73
250_S	254_H	0.790	0.73
195_G	204_R	0.790	0.73
481_E	486_S	0.789	0.73
110_A	192_G	0.788	0.73
649_I	654_Q	0.787	0.73
484_P	490_L	0.787	0.73
480_S	483_F	0.786	0.73
373_G	396_M	0.785	0.73
616_L	625_A	0.784	0.72
116_K	155_I	0.784	0.72
656_I	711_A	0.784	0.72
483_F	490_L	0.777	0.72
160_M	164_A	0.777	0.72
455_E	460_L	0.777	0.72
595_P	598_F	0.777	0.72
223_A	355_E	0.777	0.72
251_G	259_N	0.776	0.72
602_K	607_E	0.775	0.72
355_E	386_G	0.774	0.71
127_G	209_C	0.773	0.71
135_Y	156_T	0.772	0.71
108_T	194_F	0.772	0.71
112_A	134_T	0.772	0.71
663_C	667_D	0.772	0.71
678_H	682_P	0.772	0.71
385_A	431_I	0.771	0.71
229_K	235_L	0.771	0.71
288_K	382_A	0.770	0.71
558_Y	563_N	0.770	0.71
274_T	279_E	0.770	0.71
113_Q	134_T	0.768	0.71
333_R	356_L	0.767	0.71
395_I	418_S	0.766	0.71
564_L	570_V	0.765	0.71
241_R	244_D	0.765	0.71
462_Y	473_G	0.764	0.70
322_R	336_I	0.764	0.70
251_G	255_F	0.763	0.70
529_I	554_V	0.762	0.70
253_K	260_P	0.761	0.70
295_A	304_I	0.761	0.70
467_A	470_H	0.761	0.70
208_I	407_I	0.760	0.70
463_L	466_E	0.759	0.70
371_Y	414_F	0.758	0.70
249_P	254_H	0.758	0.70
646_L	654_Q	0.757	0.70
304_I	308_I	0.757	0.70
703_R	716_T	0.757	0.70
187_L	222_S	0.757	0.70
601_I	608_N	0.756	0.70
475_R	480_S	0.754	0.69
358_V	442_E	0.754	0.69
432_L	435_H	0.753	0.69
107_P	384_R	0.752	0.69
556_V	568_L	0.752	0.69
463_L	470_H	0.751	0.69
712_K	717_H	0.751	0.69
303_I	311_L	0.751	0.69
355_E	361_G	0.749	0.69
464_Q	467_A	0.749	0.69
689_H	734_G	0.747	0.69
269_I	275_A	0.747	0.69
599_K	606_F	0.745	0.69
38_S	44_K	0.744	0.68
558_Y	568_L	0.744	0.68
252_R	257_F	0.742	0.68
250_S	255_F	0.742	0.68
700_V	731_E	0.742	0.68
50_R	121_E	0.741	0.68
136_D	298_R	0.741	0.68
596_T	600_K	0.740	0.68
521_M	619_E	0.740	0.68
296_R	300_R	0.740	0.68
369_T	397_V	0.739	0.68
110_A	115_Q	0.737	0.68
693_G	724_C	0.737	0.68
625_A	631_K	0.737	0.68
373_G	377_S	0.736	0.68
431_I	435_H	0.736	0.68
561_D	564_L	0.736	0.68
655_H	665_R	0.734	0.67
268_N	272_S	0.733	0.67
517_R	526_D	0.733	0.67
490_L	500_I	0.733	0.67
58_H	110_A	0.731	0.67
169_H	212_Y	0.731	0.67
566_V	571_L	0.728	0.67
71_S	240_M	0.727	0.67
664_D	734_G	0.727	0.67
587_G	595_P	0.727	0.67
61_S	245_D	0.725	0.66
476_Y	484_P	0.724	0.66
557_E	566_V	0.723	0.66
481_E	487_N	0.722	0.66
549_A	560_T	0.722	0.66
602_K	609_I	0.721	0.66
594_L	598_F	0.720	0.66
605_T	608_N	0.718	0.66
554_V	562_A	0.718	0.66
160_M	392_S	0.717	0.66
462_Y	465_E	0.716	0.65
290_Q	340_L	0.716	0.65
589_V	597_I	0.714	0.65
200_N	432_L	0.713	0.65
656_I	714_L	0.713	0.65
94_I	102_A	0.712	0.65
660_Y	703_R	0.712	0.65
561_D	566_V	0.712	0.65
558_Y	562_A	0.711	0.65
473_G	479_A	0.710	0.65
688_D	692_G	0.710	0.65
259_N	262_I	0.709	0.65
714_L	717_H	0.709	0.65
650_S	734_G	0.708	0.65
338_R	702_K	0.707	0.64
144_R	148_R	0.706	0.64
562_A	568_L	0.706	0.64
176_F	208_I	0.706	0.64
559_Y	572_E	0.704	0.64
684_I	730_T	0.703	0.64
730_T	733_E	0.702	0.64
650_S	689_H	0.701	0.64
132_S	151_G	0.700	0.64
460_L	463_L	0.697	0.63
483_F	496_E	0.697	0.63
516_D	519_S	0.695	0.63
483_F	493_A	0.695	0.63
474_E	478_W	0.694	0.63
515_M	519_S	0.693	0.63
435_H	442_E	0.692	0.63
480_S	484_P	0.692	0.63
576_T	585_H	0.691	0.63
489_S	494_S	0.691	0.63
45_A	271_R	0.690	0.63
77_P	376_A	0.687	0.62
138_D	334_R	0.687	0.62
384_R	387_R	0.687	0.62
653_L	686_L	0.687	0.62
543_D	546_H	0.687	0.62
466_E	472_N	0.686	0.62
567_Q	570_V	0.686	0.62
103_L	202_I	0.685	0.62
670_V	686_L	0.684	0.62
592_N	620_E	0.683	0.62
139_T	147_V	0.683	0.62
83_T	118_E	0.682	0.62
553_K	556_V	0.679	0.61
136_D	151_G	0.678	0.61
270_R	274_T	0.678	0.61
272_S	277_V	0.677	0.61
656_I	660_Y	0.676	0.61
701_F	723_G	0.676	0.61
457_S	463_L	0.675	0.61
706_D	716_T	0.674	0.61
306_S	311_L	0.674	0.61
137_G	333_R	0.673	0.61
238_K	247_G	0.672	0.61
593_A	598_F	0.672	0.61
623_T	627_W	0.670	0.60
89_P	372_P	0.667	0.60
255_F	258_Y	0.666	0.60
707_I	712_K	0.666	0.60
707_I	717_H	0.664	0.60
482_S	487_N	0.663	0.60
132_S	152_H	0.663	0.60
621_L	630_I	0.662	0.59
337_E	354_L	0.661	0.59
86_Y	118_E	0.660	0.59
482_S	503_Q	0.659	0.59
341_R	360_I	0.659	0.59
141_P	145_Q	0.659	0.59
671_V	685_F	0.658	0.59
58_H	192_G	0.657	0.59
473_G	477_H	0.657	0.59
495_Q	626_A	0.657	0.59
359_D	372_P	0.656	0.59
593_A	597_I	0.656	0.59
614_I	619_E	0.655	0.59
251_G	258_Y	0.654	0.58
559_Y	573_I	0.654	0.58
108_T	151_G	0.654	0.58
136_D	327_G	0.653	0.58
672_S	734_G	0.653	0.58
552_R	555_D	0.653	0.58
302_E	325_R	0.652	0.58
477_H	484_P	0.652	0.58
576_T	581_R	0.652	0.58
110_A	188_H	0.651	0.58
566_V	573_I	0.651	0.58
273_A	276_E	0.651	0.58
723_G	728_I	0.651	0.58
159_D	353_A	0.651	0.58
165_I	346_L	0.651	0.58
115_Q	386_G	0.649	0.58
58_H	115_Q	0.649	0.58
572_E	588_D	0.649	0.58
131_K	152_H	0.649	0.58
677_A	680_G	0.649	0.58
544_W	549_A	0.649	0.58
469_L	472_N	0.648	0.58
248_A	261_P	0.647	0.58
619_E	623_T	0.646	0.58
648_G	652_V	0.646	0.58
79_A	106_F	0.644	0.57
491_R	500_I	0.643	0.57
293_V	347_G	0.642	0.57
462_Y	467_A	0.642	0.57
461_E	702_K	0.641	0.57
302_E	337_E	0.641	0.57
459_I	480_S	0.641	0.57
191_R	363_L	0.640	0.57
249_P	255_F	0.640	0.57
278_N	283_E	0.640	0.57
472_N	477_H	0.640	0.57
468_V	475_R	0.638	0.57
525_H	534_G	0.638	0.57
370_G	373_G	0.636	0.56
669_H	687_Y	0.635	0.56
253_K	257_F	0.634	0.56
112_A	350_S	0.633	0.56
456_V	464_Q	0.633	0.56
484_P	489_S	0.631	0.56
251_G	254_H	0.630	0.56
548_K	553_K	0.630	0.56
302_E	309_Q	0.629	0.56
658_P	672_S	0.629	0.56
515_M	521_M	0.629	0.56
182_I	415_F	0.629	0.56
150_A	154_V	0.629	0.56
555_D	558_Y	0.628	0.55
474_E	479_A	0.626	0.55
596_T	601_I	0.626	0.55
125_E	292_I	0.626	0.55
621_L	625_A	0.626	0.55
472_N	475_R	0.626	0.55
121_E	182_I	0.625	0.55
78_T	115_Q	0.624	0.55
410_H	413_Y	0.624	0.55
710_A	714_L	0.623	0.55
592_N	605_T	0.623	0.55
339_G	345_I	0.623	0.55
179_L	333_R	0.622	0.55
252_R	260_P	0.621	0.55
595_P	614_I	0.621	0.55
560_T	570_V	0.621	0.55
337_E	356_L	0.620	0.54
488_I	493_A	0.620	0.54
268_N	275_A	0.620	0.54
483_F	487_N	0.619	0.54
324_Y	327_G	0.618	0.54
617_P	620_E	0.618	0.54
110_A	353_A	0.618	0.54
652_V	656_I	0.617	0.54
229_K	234_Q	0.617	0.54
301_V	306_S	0.617	0.54
730_T	734_G	0.615	0.54
594_L	600_K	0.614	0.54
235_L	242_L	0.613	0.54
535_V	538_Q	0.613	0.54
112_A	136_D	0.613	0.54
576_T	583_S	0.611	0.53
277_V	283_E	0.610	0.53
114_D	354_L	0.610	0.53
268_N	276_E	0.610	0.53
624_S	630_I	0.610	0.53
560_T	573_I	0.610	0.53
648_G	651_N	0.609	0.53
717_H	722_D	0.607	0.53
711_A	732_I	0.606	0.53
338_R	410_H	0.606	0.53
650_S	655_H	0.605	0.53
254_H	258_Y	0.605	0.53
140_S	144_R	0.604	0.53
365_V	393_L	0.603	0.52
650_S	671_V	0.601	0.52
606_F	609_I	0.601	0.52
151_G	154_V	0.600	0.52
304_I	369_T	0.600	0.52
206_K	215_D	0.599	0.52
136_D	334_R	0.599	0.52
623_T	628_L	0.596	0.52
75_V	226_A	0.596	0.52
108_T	201_V	0.595	0.51
351_T	358_V	0.594	0.51
571_L	590_T	0.593	0.51
276_E	284_F	0.593	0.51
172_W	175_L	0.592	0.51
275_A	279_E	0.591	0.51
624_S	627_W	0.591	0.51
615_H	624_S	0.591	0.51
547_K	574_D	0.590	0.51
110_A	386_G	0.590	0.51
375_V	417_R	0.589	0.51
706_D	714_L	0.589	0.51
477_H	501_V	0.589	0.51
433_V	437_K	0.588	0.51
602_K	610_G	0.588	0.51
539_V	542_L	0.587	0.51
238_K	241_R	0.587	0.51
693_G	727_C	0.586	0.50
111_L	223_A	0.584	0.50
530_Y	542_L	0.584	0.50
258_Y	261_P	0.584	0.50
44_K	47_L	0.584	0.50
89_P	359_D	0.584	0.50
620_E	628_L	0.584	0.50
219_I	350_S	0.584	0.50
66_V	217_V	0.583	0.50
84_L	87_N	0.582	0.50
659_V	714_L	0.581	0.50
689_H	730_T	0.581	0.50
133_F	151_G	0.580	0.50
241_R	247_G	0.578	0.49
248_A	260_P	0.578	0.49
592_N	603_M	0.578	0.49
462_Y	468_V	0.578	0.49
162_H	353_A	0.578	0.49
292_I	348_V	0.578	0.49
291_T	664_D	0.577	0.49
238_K	245_D	0.576	0.49
250_S	257_F	0.576	0.49
564_L	567_Q	0.576	0.49
410_H	717_H	0.575	0.49
93_S	97_D	0.574	0.49
649_I	708_N	0.574	0.49
440_A	444_P	0.574	0.49
529_I	558_Y	0.572	0.49
108_T	328_Y	0.571	0.49
714_L	718_C	0.571	0.49
51_G	183_V	0.570	0.49
348_V	375_V	0.569	0.48
103_L	731_E	0.568	0.48
330_P	334_R	0.568	0.48
448_D	453_A	0.567	0.48
652_V	715_I	0.567	0.48
373_G	378_A	0.567	0.48
62_A	72_I	0.567	0.48
711_A	715_I	0.566	0.48
468_V	487_N	0.565	0.48
224_T	379_W	0.564	0.48
111_L	383_G	0.564	0.48
528_A	536_Q	0.564	0.48
114_D	351_T	0.563	0.48
497_N	502_D	0.563	0.48
480_S	493_A	0.562	0.48
528_A	535_V	0.562	0.48
586_Y	596_T	0.562	0.48
78_T	81_G	0.562	0.48
78_T	82_K	0.562	0.48
136_D	157_N	0.562	0.48
600_K	603_M	0.562	0.48
254_H	260_P	0.561	0.47
567_Q	572_E	0.561	0.47
628_L	631_K	0.561	0.47
169_H	213_G	0.561	0.47
733_E	736_K	0.560	0.47
59_Q	81_G	0.560	0.47
59_Q	82_K	0.560	0.47
487_N	493_A	0.560	0.47
41_E	53_D	0.559	0.47
351_T	387_R	0.558	0.47
706_D	721_H	0.558	0.47
110_A	355_E	0.557	0.47
617_P	622_H	0.557	0.47
523_L	531_L	0.557	0.47
574_D	624_S	0.556	0.47
702_K	709_E	0.556	0.47
218_F	292_I	0.556	0.47
318_T	573_I	0.555	0.47
645_L	649_I	0.555	0.47
135_Y	350_S	0.555	0.47
341_R	361_G	0.555	0.47
652_V	694_I	0.555	0.47
371_Y	396_M	0.554	0.47
279_E	282_K	0.554	0.47
94_I	100_N	0.554	0.47
600_K	604_T	0.553	0.46
689_H	701_F	0.553	0.46
149_K	230_E	0.552	0.46
392_S	397_V	0.551	0.46
644_Q	654_Q	0.550	0.46
108_T	136_D	0.550	0.46
637_I	640_K	0.550	0.46
620_E	627_W	0.550	0.46
532_H	538_Q	0.549	0.46
123_I	415_F	0.547	0.46
129_D	219_I	0.547	0.46
594_L	607_E	0.547	0.46
463_L	489_S	0.546	0.46
497_N	503_Q	0.546	0.46
671_V	688_D	0.546	0.46
78_T	355_E	0.546	0.46
594_L	610_G	0.545	0.46
709_E	716_T	0.545	0.46
531_L	541_K	0.545	0.46
115_Q	188_H	0.544	0.45
647_L	654_Q	0.544	0.45
162_H	382_A	0.544	0.45
230_E	233_E	0.543	0.45
602_K	624_S	0.542	0.45
706_D	722_D	0.542	0.45
58_H	203_R	0.541	0.45
230_E	374_S	0.541	0.45
376_A	392_S	0.541	0.45
568_L	571_L	0.540	0.45
268_N	282_K	0.540	0.45
520_A	526_D	0.540	0.45
64_Q	457_S	0.540	0.45
40_D	47_L	0.540	0.45
40_D	95_A	0.540	0.45
311_L	368_M	0.538	0.45
155_I	374_S	0.538	0.45
456_V	471_R	0.537	0.45
160_M	376_A	0.537	0.45
294_F	299_V	0.536	0.44
448_D	454_M	0.535	0.44
684_I	687_Y	0.534	0.44
278_N	285_L	0.534	0.44
355_E	381_Q	0.533	0.44
479_A	488_I	0.533	0.44
557_E	562_A	0.533	0.44
257_F	414_F	0.532	0.44
643_E	650_S	0.532	0.44
668_V	683_T	0.531	0.44
525_H	528_A	0.530	0.44
656_I	668_V	0.530	0.44
590_T	595_P	0.529	0.44
688_D	697_A	0.529	0.44
563_N	569_K	0.529	0.44
616_L	619_E	0.528	0.44
569_K	575_K	0.528	0.44
280_L	378_A	0.527	0.43
665_R	668_V	0.527	0.43
565_A	596_T	0.527	0.43
660_Y	666_N	0.527	0.43
90_V	104_Y	0.527	0.43
231_L	243_V	0.526	0.43
241_R	246_N	0.525	0.43
98_E	119_L	0.525	0.43
210_R	217_V	0.524	0.43
619_E	636_D	0.524	0.43
703_R	707_I	0.524	0.43
643_E	684_I	0.523	0.43
62_A	66_V	0.523	0.43
63_F	67_Q	0.522	0.43
485_A	495_Q	0.522	0.43
108_T	353_A	0.522	0.43
428_N	431_I	0.521	0.43
554_V	559_Y	0.521	0.43
281_A	347_G	0.520	0.43
163_S	348_V	0.520	0.43
345_I	527_E	0.519	0.42
135_Y	141_P	0.519	0.42
593_A	599_K	0.518	0.42
624_S	629_E	0.518	0.42
592_N	606_F	0.518	0.42
625_A	633_A	0.518	0.42
225_I	350_S	0.517	0.42
188_H	355_E	0.517	0.42
700_V	708_N	0.516	0.42
273_A	399_N	0.516	0.42
80_S	199_A	0.516	0.42
457_S	460_L	0.516	0.42
671_V	674_I	0.516	0.42
591_V	596_T	0.516	0.42
478_W	490_L	0.516	0.42
332_E	533_E	0.516	0.42
596_T	602_K	0.516	0.42
403_I	414_F	0.516	0.42
438_C	488_I	0.516	0.42
485_A	490_L	0.515	0.42
598_F	602_K	0.515	0.42
465_E	468_V	0.515	0.42
609_I	612_G	0.515	0.42
41_E	46_A	0.515	0.42
595_P	606_F	0.514	0.42
479_A	483_F	0.514	0.42
732_I	736_K	0.514	0.42
213_G	216_P	0.514	0.42
115_Q	380_Q	0.514	0.42
458_D	466_E	0.513	0.42
627_W	634_D	0.513	0.42
39_I	63_F	0.513	0.42
46_A	123_I	0.512	0.42
601_I	606_F	0.512	0.42
301_V	325_R	0.512	0.42
438_C	445_F	0.512	0.42
119_L	161_L	0.512	0.42
57_T	182_I	0.511	0.42
430_I	698_E	0.511	0.42
282_K	285_L	0.511	0.42
44_K	49_K	0.510	0.41
86_Y	89_P	0.510	0.41
198_V	224_T	0.509	0.41
304_I	697_A	0.509	0.41
705_S	710_A	0.509	0.41
725_P	731_E	0.508	0.41
250_S	256_V	0.508	0.41
599_K	607_E	0.508	0.41
77_P	227_N	0.508	0.41
437_K	441_Y	0.507	0.41
162_H	530_Y	0.507	0.41
77_P	109_K	0.506	0.41
323_G	353_A	0.506	0.41
250_S	253_K	0.506	0.41
729_G	735_I	0.504	0.41
195_G	414_F	0.504	0.41
243_V	255_F	0.504	0.41
679_T	710_A	0.502	0.40
135_Y	148_R	0.501	0.40
356_L	380_Q	0.501	0.40
520_A	528_A	0.500	0.40
358_V	631_K	0.500	0.40
600_K	606_F	0.500	0.40

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4nhoA	1	0.534	100	0.61	Contact Map
4ljyA	1	0.5554	100	0.615	Contact Map
4pxaA	1	0.5381	100	0.616	Contact Map
4a2qA	1	0.4526	100	0.617	Contact Map
4c9bA	1	0.5113	100	0.617	Contact Map
3fmpB	1	0.287	100	0.621	Contact Map
2db3A	1	0.5287	100	0.621	Contact Map
4d25A	1	0.5327	100	0.622	Contact Map
4w7sA	2	0.5648	100	0.623	Contact Map
3eiqA	1	0.4766	100	0.625	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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