GREMLIN Database
YPRA - Uncharacterized ATP-dependent helicase YprA
UniProt: P50830 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 749 (684)
Sequences: 2327 (1784)
Seq/√Len: 68.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
234_Q237_G5.5281.00
231_L236_T5.2011.00
57_T247_G4.5141.00
92_Q96_Q4.4251.00
339_G344_D4.4091.00
712_K716_T4.3911.00
90_V102_A4.3541.00
539_V551_V4.1211.00
93_S180_K4.0291.00
231_L237_G3.7651.00
232_G236_T3.6701.00
703_R706_D3.5591.00
71_S238_K3.4671.00
70_E241_R3.4531.00
74_T85_C3.2591.00
382_A394_I3.2281.00
484_P488_I3.2161.00
335_E339_G3.1801.00
271_R276_E3.1371.00
231_L234_Q3.1091.00
540_E552_R3.0791.00
187_L220_C3.0501.00
398_A408_V3.0311.00
184_I202_I3.0101.00
243_V247_G3.0001.00
206_K218_F2.9951.00
284_F365_V2.8731.00
232_G237_G2.8701.00
182_I218_F2.8261.00
239_P243_V2.8031.00
105_L156_T2.7241.00
230_E236_T2.7231.00
230_E237_G2.7041.00
566_V570_V2.6631.00
566_V569_K2.6041.00
366_C385_A2.6021.00
231_L235_L2.5871.00
206_K238_K2.5581.00
270_R276_E2.5501.00
40_D92_Q2.5311.00
87_N104_Y2.5121.00
86_Y106_F2.4811.00
230_E234_Q2.4791.00
647_L651_N2.4791.00
90_V183_V2.4521.00
57_T61_S2.4081.00
320_S346_L2.3981.00
233_E237_G2.3851.00
295_A301_V2.3461.00
44_K48_S2.3451.00
101_R152_H2.3161.00
65_Y243_V2.3001.00
352_N381_Q2.2711.00
293_V367_V2.2491.00
66_V72_I2.2381.00
69_G217_V2.2081.00
66_V219_I2.1731.00
571_L574_D2.1681.00
713_Q717_H2.1581.00
277_V284_F2.1541.00
338_R342_E2.1471.00
589_V625_A2.1361.00
699_E703_R2.0651.00
236_T243_V2.0651.00
109_K157_N2.0621.00
233_E236_T2.0601.00
301_V305_L2.0331.00
676_A679_T1.9981.00
182_I206_K1.9911.00
450_E454_M1.9861.00
196_S424_I1.9771.00
67_Q92_Q1.9681.00
599_K602_K1.9531.00
705_S709_E1.9481.00
244_D247_G1.9441.00
647_L733_E1.9361.00
229_K233_E1.9061.00
83_T87_N1.8981.00
41_E45_A1.8951.00
236_T240_M1.8941.00
295_A349_V1.8551.00
710_A713_Q1.8511.00
460_L464_Q1.8471.00
133_F147_V1.8451.00
704_F708_N1.8431.00
60_Y64_Q1.8421.00
253_K256_V1.8421.00
240_M247_G1.8261.00
587_G627_W1.8211.00
229_K242_L1.8211.00
595_P599_K1.8201.00
281_A293_V1.8151.00
210_R215_D1.8121.00
713_Q716_T1.8041.00
94_I152_H1.7891.00
650_S654_Q1.7891.00
723_G729_G1.7841.00
243_V246_N1.7721.00
93_S181_Y1.7631.00
87_N119_L1.7411.00
448_D452_G1.7391.00
515_M524_L1.7381.00
242_L246_N1.7251.00
591_V598_F1.7121.00
76_T80_S1.7041.00
570_V573_I1.7011.00
720_C727_C1.7001.00
292_I366_C1.6991.00
333_R337_E1.6991.00
72_I243_V1.6740.99
724_C727_C1.6740.99
201_V490_L1.6520.99
478_W483_F1.6480.99
451_F454_M1.6420.99
324_Y337_E1.6340.99
119_L153_I1.6300.99
461_E464_Q1.6280.99
490_L495_Q1.6210.99
230_E235_L1.6030.99
709_E713_Q1.6020.99
116_K120_N1.5990.99
40_D43_I1.5630.99
484_P487_N1.5580.99
485_A491_R1.5540.99
188_H380_Q1.5490.99
135_Y160_M1.5440.99
242_L247_G1.5440.99
598_F601_I1.5300.99
277_V397_V1.5210.99
143_I146_K1.5200.99
71_S217_V1.5180.99
650_S670_V1.5090.99
65_Y72_I1.5080.99
72_I217_V1.5080.99
108_T159_D1.5000.99
86_Y221_T1.4830.99
462_Y466_E1.4800.99
58_H76_T1.4790.99
481_E484_P1.4770.99
557_E560_T1.4730.99
579_K582_T1.4720.99
85_C89_P1.4710.99
211_F443_L1.4690.99
329_L332_E1.4630.99
63_F88_L1.4620.99
65_Y70_E1.4610.99
249_P252_R1.4560.98
290_Q346_L1.4540.98
283_E286_K1.4440.98
720_C724_C1.4430.98
237_G243_V1.4380.98
340_L348_V1.4300.98
595_P600_K1.4290.98
240_M243_V1.4240.98
700_V707_I1.4180.98
39_I44_K1.4170.98
156_T161_L1.4170.98
486_S492_S1.4120.98
457_S461_E1.4110.98
303_I307_H1.4070.98
84_L118_E1.4060.98
654_Q670_V1.4050.98
117_S341_R1.4050.98
560_T566_V1.4010.98
94_I153_I1.3940.98
58_H80_S1.3940.98
660_Y706_D1.3940.98
252_R255_F1.3900.98
278_N282_K1.3720.98
368_M382_A1.3630.98
439_A442_E1.3630.98
45_A48_S1.3630.98
651_N733_E1.3600.98
563_N568_L1.3600.98
199_A203_R1.3580.98
476_Y479_A1.3500.98
48_S53_D1.3440.97
486_S490_L1.3430.97
476_Y482_S1.3420.97
577_K580_S1.3330.97
93_S100_N1.3320.97
220_C236_T1.3280.97
62_A85_C1.3270.97
368_M381_Q1.3250.97
252_R391_E1.3250.97
55_L88_L1.3150.97
456_V460_L1.3120.97
239_P247_G1.3110.97
61_S64_Q1.3090.97
189_T356_L1.3070.97
473_G480_S1.3070.97
599_K603_M1.3040.97
651_N654_Q1.3030.97
650_S672_S1.2940.97
43_I47_L1.2910.97
304_I307_H1.2900.97
282_K286_K1.2860.97
324_Y353_A1.2830.97
524_L530_Y1.2820.97
259_N405_Q1.2790.97
322_R533_E1.2670.96
484_P491_R1.2660.96
276_E279_E1.2630.96
78_T111_L1.2600.96
618_E624_S1.2580.96
117_S121_E1.2550.96
109_K136_D1.2430.96
271_R275_A1.2410.96
471_R474_E1.2380.96
307_H310_E1.2370.96
563_N566_V1.2350.96
277_V281_A1.2350.96
324_Y328_Y1.2280.96
616_L620_E1.2270.96
476_Y481_E1.2260.96
563_N570_V1.2240.96
70_E239_P1.2180.95
238_K243_V1.2170.95
403_I725_P1.2170.95
292_I350_S1.2160.95
322_R339_G1.2150.95
654_Q672_S1.2100.95
627_W631_K1.2100.95
109_K138_D1.2090.95
596_T599_K1.2090.95
269_I272_S1.2050.95
474_E477_H1.2030.95
304_I311_L1.2020.95
296_R381_Q1.2010.95
113_Q136_D1.2000.95
649_I652_V1.1950.95
679_T682_P1.1920.95
269_I273_A1.1900.95
562_A572_E1.1770.95
531_L536_Q1.1770.95
255_F378_A1.1760.94
366_C394_I1.1740.94
105_L157_N1.1720.94
459_I463_L1.1670.94
188_H356_L1.1660.94
135_Y164_A1.1640.94
156_T160_M1.1600.94
698_E702_K1.1580.94
605_T610_G1.1420.94
660_Y710_A1.1380.93
485_A492_S1.1340.93
65_Y241_R1.1310.93
731_E734_G1.1300.93
569_K573_I1.1160.93
589_V595_P1.1130.93
101_R174_S1.1130.93
478_W481_E1.1120.93
87_N118_E1.1030.92
139_T144_R1.1030.92
249_P253_K1.1000.92
305_L323_G1.0990.92
306_S309_Q1.0980.92
252_R256_V1.0950.92
232_G235_L1.0950.92
361_G388_R1.0910.92
181_Y219_I1.0900.92
476_Y483_F1.0900.92
617_P625_A1.0830.92
467_A471_R1.0800.92
483_F486_S1.0790.92
145_Q149_K1.0790.92
479_A482_S1.0760.91
428_N435_H1.0700.91
209_C214_S1.0690.91
253_K259_N1.0680.91
562_A565_A1.0670.91
498_V502_D1.0660.91
97_D180_K1.0650.91
39_I47_L1.0630.91
38_S41_E1.0630.91
65_Y68_K1.0590.91
90_V181_Y1.0580.91
182_I202_I1.0570.91
456_V462_Y1.0560.91
254_H257_F1.0550.91
144_R147_V1.0550.91
669_H689_H1.0540.91
604_T609_I1.0520.90
305_L309_Q1.0520.90
576_T580_S1.0510.90
498_V501_V1.0460.90
97_D101_R1.0460.90
588_D622_H1.0460.90
590_T620_E1.0460.90
184_I198_V1.0430.90
562_A566_V1.0380.90
242_L245_D1.0350.90
378_A396_M1.0320.90
364_Q390_G1.0320.90
61_S65_Y1.0310.90
689_H732_I1.0310.90
290_Q364_Q1.0290.89
565_A570_V1.0290.89
38_S67_Q1.0280.89
491_R494_S1.0250.89
558_Y566_V1.0220.89
595_P602_K1.0220.89
679_T683_T1.0220.89
85_C123_I1.0190.89
64_Q68_K1.0180.89
425_N699_E1.0150.89
110_A380_Q1.0150.89
303_I531_L1.0150.89
55_L63_F1.0130.89
647_L650_S1.0130.89
61_S241_R1.0130.89
595_P610_G1.0130.89
723_G733_E1.0070.88
528_A598_F1.0060.88
599_K608_N1.0060.88
670_V689_H1.0040.88
725_P733_E1.0010.88
145_Q148_R1.0000.88
232_G243_V0.9990.88
617_P621_L0.9990.88
589_V593_A0.9980.88
487_N494_S0.9970.88
577_K705_S0.9970.88
586_Y624_S0.9940.88
233_E239_P0.9930.88
578_E581_R0.9920.88
569_K590_T0.9910.88
526_D541_K0.9900.88
78_T223_A0.9830.87
111_L115_Q0.9810.87
487_N491_R0.9810.87
490_L494_S0.9790.87
647_L672_S0.9780.87
240_M245_D0.9750.87
554_V557_E0.9750.87
573_I576_T0.9750.87
652_V711_A0.9720.87
615_H620_E0.9710.87
412_E416_N0.9700.86
704_F707_I0.9700.86
592_N595_P0.9680.86
707_I710_A0.9680.86
270_R273_A0.9680.86
497_N501_V0.9670.86
481_E490_L0.9670.86
614_I617_P0.9650.86
702_K710_A0.9640.86
379_W382_A0.9640.86
94_I130_I0.9630.86
606_F611_S0.9620.86
272_S275_A0.9610.86
603_M606_F0.9610.86
73_V220_C0.9600.86
239_P242_L0.9580.86
124_D127_G0.9550.86
648_G728_I0.9500.85
108_T356_L0.9490.85
448_D451_F0.9460.85
704_F714_L0.9440.85
159_D194_F0.9430.85
524_L549_A0.9430.85
702_K706_D0.9430.85
355_E380_Q0.9390.85
383_G386_G0.9380.85
450_E453_A0.9380.85
463_L467_A0.9370.85
700_V704_F0.9370.85
445_F460_L0.9360.84
664_D685_F0.9330.84
497_N500_I0.9330.84
204_R435_H0.9320.84
206_K210_R0.9300.84
670_V673_Q0.9290.84
115_Q355_E0.9280.84
617_P624_S0.9280.84
559_Y566_V0.9270.84
708_N712_K0.9250.84
280_L367_V0.9220.84
568_L573_I0.9180.83
479_A486_S0.9180.83
302_E305_L0.9180.83
479_A484_P0.9170.83
478_W484_P0.9140.83
280_L284_F0.9140.83
111_L359_D0.9120.83
111_L372_P0.9090.83
192_G355_E0.9090.83
475_R478_W0.9070.83
437_K442_E0.9060.82
670_V734_G0.9060.82
479_A487_N0.9030.82
456_V459_I0.9030.82
654_Q730_T0.9030.82
657_V668_V0.9020.82
159_D164_A0.9000.82
303_I306_S0.9000.82
706_D712_K0.8980.82
629_E683_T0.8980.82
325_R328_Y0.8970.82
502_D508_N0.8960.82
279_E286_K0.8960.82
78_T383_G0.8950.82
268_N277_V0.8950.82
614_I618_E0.8940.82
488_I491_R0.8940.82
599_K611_S0.8900.81
74_T221_T0.8900.81
368_M378_A0.8890.81
560_T564_L0.8890.81
550_Y553_K0.8890.81
277_V369_T0.8870.81
279_E284_F0.8830.81
675_K678_H0.8830.81
229_K236_T0.8790.81
78_T386_G0.8790.81
482_S485_A0.8780.80
557_E568_L0.8780.80
653_L711_A0.8780.80
478_W486_S0.8770.80
619_E624_S0.8760.80
706_D710_A0.8740.80
602_K605_T0.8740.80
356_L402_P0.8740.80
618_E625_A0.8700.80
593_A601_I0.8690.80
223_A383_G0.8690.80
307_H311_L0.8680.80
670_V735_I0.8670.80
239_P244_D0.8670.80
284_F289_V0.8660.80
625_A628_L0.8640.79
78_T89_P0.8630.79
229_K237_G0.8600.79
587_G601_I0.8600.79
251_G257_F0.8590.79
274_T350_S0.8570.79
463_L468_V0.8570.79
600_K610_G0.8570.79
254_H259_N0.8540.79
632_T635_E0.8530.79
626_A631_K0.8500.78
500_I551_V0.8490.78
380_Q384_R0.8450.78
149_K210_R0.8440.78
568_L671_V0.8440.78
103_L182_I0.8430.78
490_L493_A0.8420.78
365_V395_I0.8410.78
86_Y160_M0.8390.77
235_L238_K0.8390.77
55_L181_Y0.8390.77
110_A114_D0.8370.77
529_I538_Q0.8370.77
374_S662_M0.8360.77
459_I464_Q0.8350.77
62_A221_T0.8350.77
543_D560_T0.8350.77
435_H438_C0.8340.77
588_D592_N0.8330.77
592_N598_F0.8320.77
597_I611_S0.8320.77
479_A495_Q0.8310.77
559_Y568_L0.8310.77
272_S276_E0.8300.77
486_S493_A0.8290.77
657_V700_V0.8290.77
525_H532_H0.8270.76
655_H658_P0.8250.76
719_P726_S0.8220.76
273_A277_V0.8220.76
191_R664_D0.8220.76
111_L114_D0.8210.76
67_Q96_Q0.8210.76
435_H440_A0.8210.76
712_K715_I0.8200.76
520_A524_L0.8190.76
703_R712_K0.8190.76
597_I603_M0.8190.76
699_E702_K0.8180.76
482_S493_A0.8150.75
552_R556_V0.8150.75
706_D709_E0.8150.75
520_A523_L0.8130.75
666_N732_I0.8110.75
461_E471_R0.8100.75
101_R178_N0.8100.75
414_F417_R0.8100.75
428_N440_A0.8100.75
106_F115_Q0.8090.75
255_F260_P0.8070.75
587_G598_F0.8060.74
459_I462_Y0.8060.74
278_N286_K0.8050.74
153_I182_I0.8040.74
485_A489_S0.8040.74
73_V187_L0.8040.74
114_D353_A0.8030.74
597_I601_I0.8030.74
255_F259_N0.8000.74
367_V397_V0.8000.74
725_P734_G0.7990.74
151_G381_Q0.7970.74
89_P111_L0.7970.74
223_A386_G0.7960.74
275_A278_N0.7950.73
115_Q192_G0.7950.73
593_A596_T0.7940.73
552_R557_E0.7930.73
732_I735_I0.7930.73
590_T622_H0.7910.73
500_I504_S0.7910.73
250_S254_H0.7900.73
195_G204_R0.7900.73
481_E486_S0.7890.73
110_A192_G0.7880.73
649_I654_Q0.7870.73
484_P490_L0.7870.73
480_S483_F0.7860.73
373_G396_M0.7850.73
616_L625_A0.7840.72
116_K155_I0.7840.72
656_I711_A0.7840.72
483_F490_L0.7770.72
160_M164_A0.7770.72
455_E460_L0.7770.72
595_P598_F0.7770.72
223_A355_E0.7770.72
251_G259_N0.7760.72
602_K607_E0.7750.72
355_E386_G0.7740.71
127_G209_C0.7730.71
135_Y156_T0.7720.71
108_T194_F0.7720.71
112_A134_T0.7720.71
663_C667_D0.7720.71
678_H682_P0.7720.71
385_A431_I0.7710.71
229_K235_L0.7710.71
288_K382_A0.7700.71
558_Y563_N0.7700.71
274_T279_E0.7700.71
113_Q134_T0.7680.71
333_R356_L0.7670.71
395_I418_S0.7660.71
564_L570_V0.7650.71
241_R244_D0.7650.71
462_Y473_G0.7640.70
322_R336_I0.7640.70
251_G255_F0.7630.70
529_I554_V0.7620.70
253_K260_P0.7610.70
295_A304_I0.7610.70
467_A470_H0.7610.70
208_I407_I0.7600.70
463_L466_E0.7590.70
371_Y414_F0.7580.70
249_P254_H0.7580.70
646_L654_Q0.7570.70
304_I308_I0.7570.70
703_R716_T0.7570.70
187_L222_S0.7570.70
601_I608_N0.7560.70
475_R480_S0.7540.69
358_V442_E0.7540.69
432_L435_H0.7530.69
107_P384_R0.7520.69
556_V568_L0.7520.69
463_L470_H0.7510.69
712_K717_H0.7510.69
303_I311_L0.7510.69
355_E361_G0.7490.69
464_Q467_A0.7490.69
689_H734_G0.7470.69
269_I275_A0.7470.69
599_K606_F0.7450.69
38_S44_K0.7440.68
558_Y568_L0.7440.68
252_R257_F0.7420.68
250_S255_F0.7420.68
700_V731_E0.7420.68
50_R121_E0.7410.68
136_D298_R0.7410.68
596_T600_K0.7400.68
521_M619_E0.7400.68
296_R300_R0.7400.68
369_T397_V0.7390.68
110_A115_Q0.7370.68
693_G724_C0.7370.68
625_A631_K0.7370.68
373_G377_S0.7360.68
431_I435_H0.7360.68
561_D564_L0.7360.68
655_H665_R0.7340.67
268_N272_S0.7330.67
517_R526_D0.7330.67
490_L500_I0.7330.67
58_H110_A0.7310.67
169_H212_Y0.7310.67
566_V571_L0.7280.67
71_S240_M0.7270.67
664_D734_G0.7270.67
587_G595_P0.7270.67
61_S245_D0.7250.66
476_Y484_P0.7240.66
557_E566_V0.7230.66
481_E487_N0.7220.66
549_A560_T0.7220.66
602_K609_I0.7210.66
594_L598_F0.7200.66
605_T608_N0.7180.66
554_V562_A0.7180.66
160_M392_S0.7170.66
462_Y465_E0.7160.65
290_Q340_L0.7160.65
589_V597_I0.7140.65
200_N432_L0.7130.65
656_I714_L0.7130.65
94_I102_A0.7120.65
660_Y703_R0.7120.65
561_D566_V0.7120.65
558_Y562_A0.7110.65
473_G479_A0.7100.65
688_D692_G0.7100.65
259_N262_I0.7090.65
714_L717_H0.7090.65
650_S734_G0.7080.65
338_R702_K0.7070.64
144_R148_R0.7060.64
562_A568_L0.7060.64
176_F208_I0.7060.64
559_Y572_E0.7040.64
684_I730_T0.7030.64
730_T733_E0.7020.64
650_S689_H0.7010.64
132_S151_G0.7000.64
460_L463_L0.6970.63
483_F496_E0.6970.63
516_D519_S0.6950.63
483_F493_A0.6950.63
474_E478_W0.6940.63
515_M519_S0.6930.63
435_H442_E0.6920.63
480_S484_P0.6920.63
576_T585_H0.6910.63
489_S494_S0.6910.63
45_A271_R0.6900.63
77_P376_A0.6870.62
138_D334_R0.6870.62
384_R387_R0.6870.62
653_L686_L0.6870.62
543_D546_H0.6870.62
466_E472_N0.6860.62
567_Q570_V0.6860.62
103_L202_I0.6850.62
670_V686_L0.6840.62
592_N620_E0.6830.62
139_T147_V0.6830.62
83_T118_E0.6820.62
553_K556_V0.6790.61
136_D151_G0.6780.61
270_R274_T0.6780.61
272_S277_V0.6770.61
656_I660_Y0.6760.61
701_F723_G0.6760.61
457_S463_L0.6750.61
706_D716_T0.6740.61
306_S311_L0.6740.61
137_G333_R0.6730.61
238_K247_G0.6720.61
593_A598_F0.6720.61
623_T627_W0.6700.60
89_P372_P0.6670.60
255_F258_Y0.6660.60
707_I712_K0.6660.60
707_I717_H0.6640.60
482_S487_N0.6630.60
132_S152_H0.6630.60
621_L630_I0.6620.59
337_E354_L0.6610.59
86_Y118_E0.6600.59
482_S503_Q0.6590.59
341_R360_I0.6590.59
141_P145_Q0.6590.59
671_V685_F0.6580.59
58_H192_G0.6570.59
473_G477_H0.6570.59
495_Q626_A0.6570.59
359_D372_P0.6560.59
593_A597_I0.6560.59
614_I619_E0.6550.59
251_G258_Y0.6540.58
559_Y573_I0.6540.58
108_T151_G0.6540.58
136_D327_G0.6530.58
672_S734_G0.6530.58
552_R555_D0.6530.58
302_E325_R0.6520.58
477_H484_P0.6520.58
576_T581_R0.6520.58
110_A188_H0.6510.58
566_V573_I0.6510.58
273_A276_E0.6510.58
723_G728_I0.6510.58
159_D353_A0.6510.58
165_I346_L0.6510.58
115_Q386_G0.6490.58
58_H115_Q0.6490.58
572_E588_D0.6490.58
131_K152_H0.6490.58
677_A680_G0.6490.58
544_W549_A0.6490.58
469_L472_N0.6480.58
248_A261_P0.6470.58
619_E623_T0.6460.58
648_G652_V0.6460.58
79_A106_F0.6440.57
491_R500_I0.6430.57
293_V347_G0.6420.57
462_Y467_A0.6420.57
461_E702_K0.6410.57
302_E337_E0.6410.57
459_I480_S0.6410.57
191_R363_L0.6400.57
249_P255_F0.6400.57
278_N283_E0.6400.57
472_N477_H0.6400.57
468_V475_R0.6380.57
525_H534_G0.6380.57
370_G373_G0.6360.56
669_H687_Y0.6350.56
253_K257_F0.6340.56
112_A350_S0.6330.56
456_V464_Q0.6330.56
484_P489_S0.6310.56
251_G254_H0.6300.56
548_K553_K0.6300.56
302_E309_Q0.6290.56
658_P672_S0.6290.56
515_M521_M0.6290.56
182_I415_F0.6290.56
150_A154_V0.6290.56
555_D558_Y0.6280.55
474_E479_A0.6260.55
596_T601_I0.6260.55
125_E292_I0.6260.55
621_L625_A0.6260.55
472_N475_R0.6260.55
121_E182_I0.6250.55
78_T115_Q0.6240.55
410_H413_Y0.6240.55
710_A714_L0.6230.55
592_N605_T0.6230.55
339_G345_I0.6230.55
179_L333_R0.6220.55
252_R260_P0.6210.55
595_P614_I0.6210.55
560_T570_V0.6210.55
337_E356_L0.6200.54
488_I493_A0.6200.54
268_N275_A0.6200.54
483_F487_N0.6190.54
324_Y327_G0.6180.54
617_P620_E0.6180.54
110_A353_A0.6180.54
652_V656_I0.6170.54
229_K234_Q0.6170.54
301_V306_S0.6170.54
730_T734_G0.6150.54
594_L600_K0.6140.54
235_L242_L0.6130.54
535_V538_Q0.6130.54
112_A136_D0.6130.54
576_T583_S0.6110.53
277_V283_E0.6100.53
114_D354_L0.6100.53
268_N276_E0.6100.53
624_S630_I0.6100.53
560_T573_I0.6100.53
648_G651_N0.6090.53
717_H722_D0.6070.53
711_A732_I0.6060.53
338_R410_H0.6060.53
650_S655_H0.6050.53
254_H258_Y0.6050.53
140_S144_R0.6040.53
365_V393_L0.6030.52
650_S671_V0.6010.52
606_F609_I0.6010.52
151_G154_V0.6000.52
304_I369_T0.6000.52
206_K215_D0.5990.52
136_D334_R0.5990.52
623_T628_L0.5960.52
75_V226_A0.5960.52
108_T201_V0.5950.51
351_T358_V0.5940.51
571_L590_T0.5930.51
276_E284_F0.5930.51
172_W175_L0.5920.51
275_A279_E0.5910.51
624_S627_W0.5910.51
615_H624_S0.5910.51
547_K574_D0.5900.51
110_A386_G0.5900.51
375_V417_R0.5890.51
706_D714_L0.5890.51
477_H501_V0.5890.51
433_V437_K0.5880.51
602_K610_G0.5880.51
539_V542_L0.5870.51
238_K241_R0.5870.51
693_G727_C0.5860.50
111_L223_A0.5840.50
530_Y542_L0.5840.50
258_Y261_P0.5840.50
44_K47_L0.5840.50
89_P359_D0.5840.50
620_E628_L0.5840.50
219_I350_S0.5840.50
66_V217_V0.5830.50
84_L87_N0.5820.50
659_V714_L0.5810.50
689_H730_T0.5810.50
133_F151_G0.5800.50
241_R247_G0.5780.49
248_A260_P0.5780.49
592_N603_M0.5780.49
462_Y468_V0.5780.49
162_H353_A0.5780.49
292_I348_V0.5780.49
291_T664_D0.5770.49
238_K245_D0.5760.49
250_S257_F0.5760.49
564_L567_Q0.5760.49
410_H717_H0.5750.49
93_S97_D0.5740.49
649_I708_N0.5740.49
440_A444_P0.5740.49
529_I558_Y0.5720.49
108_T328_Y0.5710.49
714_L718_C0.5710.49
51_G183_V0.5700.49
348_V375_V0.5690.48
103_L731_E0.5680.48
330_P334_R0.5680.48
448_D453_A0.5670.48
652_V715_I0.5670.48
373_G378_A0.5670.48
62_A72_I0.5670.48
711_A715_I0.5660.48
468_V487_N0.5650.48
224_T379_W0.5640.48
111_L383_G0.5640.48
528_A536_Q0.5640.48
114_D351_T0.5630.48
497_N502_D0.5630.48
480_S493_A0.5620.48
528_A535_V0.5620.48
586_Y596_T0.5620.48
78_T81_G0.5620.48
78_T82_K0.5620.48
136_D157_N0.5620.48
600_K603_M0.5620.48
254_H260_P0.5610.47
567_Q572_E0.5610.47
628_L631_K0.5610.47
169_H213_G0.5610.47
733_E736_K0.5600.47
59_Q81_G0.5600.47
59_Q82_K0.5600.47
487_N493_A0.5600.47
41_E53_D0.5590.47
351_T387_R0.5580.47
706_D721_H0.5580.47
110_A355_E0.5570.47
617_P622_H0.5570.47
523_L531_L0.5570.47
574_D624_S0.5560.47
702_K709_E0.5560.47
218_F292_I0.5560.47
318_T573_I0.5550.47
645_L649_I0.5550.47
135_Y350_S0.5550.47
341_R361_G0.5550.47
652_V694_I0.5550.47
371_Y396_M0.5540.47
279_E282_K0.5540.47
94_I100_N0.5540.47
600_K604_T0.5530.46
689_H701_F0.5530.46
149_K230_E0.5520.46
392_S397_V0.5510.46
644_Q654_Q0.5500.46
108_T136_D0.5500.46
637_I640_K0.5500.46
620_E627_W0.5500.46
532_H538_Q0.5490.46
123_I415_F0.5470.46
129_D219_I0.5470.46
594_L607_E0.5470.46
463_L489_S0.5460.46
497_N503_Q0.5460.46
671_V688_D0.5460.46
78_T355_E0.5460.46
594_L610_G0.5450.46
709_E716_T0.5450.46
531_L541_K0.5450.46
115_Q188_H0.5440.45
647_L654_Q0.5440.45
162_H382_A0.5440.45
230_E233_E0.5430.45
602_K624_S0.5420.45
706_D722_D0.5420.45
58_H203_R0.5410.45
230_E374_S0.5410.45
376_A392_S0.5410.45
568_L571_L0.5400.45
268_N282_K0.5400.45
520_A526_D0.5400.45
64_Q457_S0.5400.45
40_D47_L0.5400.45
40_D95_A0.5400.45
311_L368_M0.5380.45
155_I374_S0.5380.45
456_V471_R0.5370.45
160_M376_A0.5370.45
294_F299_V0.5360.44
448_D454_M0.5350.44
684_I687_Y0.5340.44
278_N285_L0.5340.44
355_E381_Q0.5330.44
479_A488_I0.5330.44
557_E562_A0.5330.44
257_F414_F0.5320.44
643_E650_S0.5320.44
668_V683_T0.5310.44
525_H528_A0.5300.44
656_I668_V0.5300.44
590_T595_P0.5290.44
688_D697_A0.5290.44
563_N569_K0.5290.44
616_L619_E0.5280.44
569_K575_K0.5280.44
280_L378_A0.5270.43
665_R668_V0.5270.43
565_A596_T0.5270.43
660_Y666_N0.5270.43
90_V104_Y0.5270.43
231_L243_V0.5260.43
241_R246_N0.5250.43
98_E119_L0.5250.43
210_R217_V0.5240.43
619_E636_D0.5240.43
703_R707_I0.5240.43
643_E684_I0.5230.43
62_A66_V0.5230.43
63_F67_Q0.5220.43
485_A495_Q0.5220.43
108_T353_A0.5220.43
428_N431_I0.5210.43
554_V559_Y0.5210.43
281_A347_G0.5200.43
163_S348_V0.5200.43
345_I527_E0.5190.42
135_Y141_P0.5190.42
593_A599_K0.5180.42
624_S629_E0.5180.42
592_N606_F0.5180.42
625_A633_A0.5180.42
225_I350_S0.5170.42
188_H355_E0.5170.42
700_V708_N0.5160.42
273_A399_N0.5160.42
80_S199_A0.5160.42
457_S460_L0.5160.42
671_V674_I0.5160.42
591_V596_T0.5160.42
478_W490_L0.5160.42
332_E533_E0.5160.42
596_T602_K0.5160.42
403_I414_F0.5160.42
438_C488_I0.5160.42
485_A490_L0.5150.42
598_F602_K0.5150.42
465_E468_V0.5150.42
609_I612_G0.5150.42
41_E46_A0.5150.42
595_P606_F0.5140.42
479_A483_F0.5140.42
732_I736_K0.5140.42
213_G216_P0.5140.42
115_Q380_Q0.5140.42
458_D466_E0.5130.42
627_W634_D0.5130.42
39_I63_F0.5130.42
46_A123_I0.5120.42
601_I606_F0.5120.42
301_V325_R0.5120.42
438_C445_F0.5120.42
119_L161_L0.5120.42
57_T182_I0.5110.42
430_I698_E0.5110.42
282_K285_L0.5110.42
44_K49_K0.5100.41
86_Y89_P0.5100.41
198_V224_T0.5090.41
304_I697_A0.5090.41
705_S710_A0.5090.41
725_P731_E0.5080.41
250_S256_V0.5080.41
599_K607_E0.5080.41
77_P227_N0.5080.41
437_K441_Y0.5070.41
162_H530_Y0.5070.41
77_P109_K0.5060.41
323_G353_A0.5060.41
250_S253_K0.5060.41
729_G735_I0.5040.41
195_G414_F0.5040.41
243_V255_F0.5040.41
679_T710_A0.5020.40
135_Y148_R0.5010.40
356_L380_Q0.5010.40
520_A528_A0.5000.40
358_V631_K0.5000.40
600_K606_F0.5000.40
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4nhoA 1 0.534 100 0.61 Contact Map
4ljyA 1 0.5554 100 0.615 Contact Map
4pxaA 1 0.5381 100 0.616 Contact Map
4a2qA 1 0.4526 100 0.617 Contact Map
4c9bA 1 0.5113 100 0.617 Contact Map
3fmpB 1 0.287 100 0.621 Contact Map
2db3A 1 0.5287 100 0.621 Contact Map
4d25A 1 0.5327 100 0.622 Contact Map
4w7sA 2 0.5648 100 0.623 Contact Map
3eiqA 1 0.4766 100 0.625 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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