RECS - BACSU - GREMLIN Contacts

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RECS - Probable ATP-dependent DNA helicase RecS

UniProt:	P50729	Sequences: MTKLQQTLYQFFGFTSFKKGQQDIIESILSGKDTIAMLPTGGGKSLCYQLPGYMLDGMVLIVSPLLSLMEDQVQQLKARGEKRAAALNSMLNRQERQFVLEHIHRYKFLYLSPEALQSPYVLEKLKSVPISLFVIDEAHCISEWGHDFRPDYSKLGQLRKKLGHPPVLALTATATKETLQDVMNLLELQHAVRHLNSVNRPNIALRVENAADTAEKIDRVIQLVENLQGPGIVYCPTRKWAKELAGEIKSKTSSRADFYHGGLESGDRILIQQQFIHNQLDVICCTNAFGMGVDKPDIRYVIHFHLPQTAEAFMQEIGRAGRDGKPSVSILLRAPGDFELQEQIIQMESVTAEEIADVIRVLEKTEERDERRLRDVLLQYGVGETQARMMIHLFMQGKTSVELMKKEISYRMELKLEKMHRVSFLLQRDGCLRQALLTYFDESYEPDDGNLPCCSHCGFDLSLYEQKGERSKMAPLDSWSSELHRIFSLQTVGELN	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	496 (406)
Sequences:	19455 (12564)
Seq/√Len:	623.5

ECOLI - RECQ DEAD YFJK RECG YEJH SRMB DBPA RHLE RAPA RHLB
BACSU - RECS RECQ DBPA CSHA YPRA RECG CSHB YWQA COMFA YFML YQHH
HALSA - HELS Q9HN80 Q9HNB2 RAD25 O52003 Q9HMW5 Q9HQA5 O51997
SULSO - Q981C8 Q97X74 HELS Q97ZF9 HELX Q97YC4 Q97Y93 Q97WW1 Q980C0 Q97X64 Q97WT0 Q97ZV2 Q97ZF3 Q97YQ4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
49_Q	76_L	5.238	1.00
28_I	168_L	3.723	1.00
48_Y	134_V	3.674	1.00
274_Q	279_Q	3.641	1.00
52_G	59_V	3.597	1.00
63_S	72_Q	3.462	1.00
273_Q	277_H	3.425	1.00
238_R	262_G	3.394	1.00
257_D	280_L	3.373	1.00
235_C	241_A	3.340	1.00
111_L	116_L	3.269	1.00
39_P	42_G	3.204	1.00
254_S	282_V	3.055	1.00
235_C	244_L	2.980	1.00
20_G	36_A	2.973	1.00
73_V	77_K	2.904	1.00
257_D	274_Q	2.845	1.00
341_Q	345_I	2.764	1.00
270_L	274_Q	2.760	1.00
245_A	256_A	2.630	1.00
29_L	54_M	2.579	1.00
317_I	329_S	2.525	1.00
231_G	300_Y	2.515	1.00
235_C	284_C	2.505	1.00
306_L	331_L	2.464	1.00
205_L	317_I	2.357	1.00
156_G	160_K	2.329	1.00
221_I	252_T	2.166	1.00
242_K	258_F	2.152	1.00
204_A	328_V	2.136	1.00
229_G	299_R	2.102	1.00
255_R	281_D	2.044	1.00
28_I	34_T	2.039	1.00
200_R	203_I	1.989	1.00
178_T	181_D	1.983	1.00
223_L	226_N	1.968	1.00
245_A	258_F	1.957	1.00
48_Y	170_L	1.949	1.00
297_D	325_K	1.924	1.00
59_V	132_L	1.924	1.00
206_R	328_V	1.923	1.00
14_F	46_L	1.915	1.00
245_A	249_K	1.880	1.00
289_F	293_V	1.872	1.00
32_K	190_H	1.864	1.00
119_P	124_K	1.829	1.00
220_V	302_I	1.824	1.00
75_Q	78_A	1.821	1.00
245_A	284_C	1.797	1.00
178_T	182_V	1.770	1.00
248_I	284_C	1.768	1.00
269_I	273_Q	1.758	1.00
33_D	169_A	1.755	1.00
138_A	169_A	1.748	1.00
241_A	260_H	1.740	1.00
92_N	95_E	1.725	1.00
219_R	222_Q	1.719	1.00
73_V	84_A	1.716	1.00
263_L	271_I	1.690	1.00
58_M	131_S	1.675	1.00
244_L	284_C	1.672	1.00
240_W	305_H	1.666	1.00
52_G	134_V	1.663	1.00
85_A	106_Y	1.659	1.00
359_I	362_L	1.645	1.00
412_M	415_K	1.625	1.00
257_D	271_I	1.589	1.00
74_Q	78_A	1.586	1.00
76_L	108_F	1.580	1.00
422_V	425_L	1.576	1.00
133_F	167_V	1.574	1.00
358_V	362_L	1.567	1.00
48_Y	72_Q	1.567	1.00
303_H	317_I	1.565	1.00
285_C	289_F	1.545	1.00
401_V	405_K	1.541	1.00
36_A	170_L	1.534	1.00
139_H	291_M	1.510	1.00
60_L	130_I	1.506	1.00
52_G	132_L	1.506	1.00
55_L	132_L	1.492	1.00
106_Y	109_L	1.488	1.00
223_L	227_L	1.488	1.00
390_M	393_L	1.452	1.00
233_V	282_V	1.423	1.00
264_E	267_D	1.415	1.00
62_V	116_L	1.414	1.00
62_V	111_L	1.412	1.00
213_T	216_K	1.408	1.00
271_I	280_L	1.400	1.00
244_L	304_F	1.398	1.00
220_V	304_F	1.370	1.00
338_F	342_E	1.357	1.00
205_L	313_F	1.352	1.00
241_A	258_F	1.343	1.00
76_L	110_Y	1.341	1.00
217_I	247_E	1.338	1.00
348_E	352_A	1.337	1.00
225_E	252_T	1.336	1.00
362_L	365_T	1.334	1.00
374_R	378_L	1.332	1.00
359_I	363_E	1.326	1.00
358_V	363_E	1.307	1.00
355_I	359_I	1.296	1.00
413_E	417_E	1.289	1.00
58_M	107_K	1.283	1.00
50_L	53_Y	1.273	1.00
338_F	341_Q	1.273	1.00
342_E	345_I	1.272	1.00
389_M	393_L	1.270	1.00
349_S	352_A	1.268	1.00
380_Y	383_G	1.265	1.00
357_D	361_V	1.250	1.00
303_H	316_E	1.250	1.00
76_L	84_A	1.250	1.00
376_V	380_Y	1.249	1.00
374_R	377_L	1.249	1.00
234_Y	316_E	1.245	1.00
181_D	185_L	1.240	1.00
301_V	320_A	1.237	1.00
415_K	418_K	1.235	1.00
361_V	365_T	1.232	1.00
377_L	380_Y	1.215	1.00
217_I	304_F	1.210	1.00
223_L	330_I	1.209	1.00
237_T	240_W	1.206	1.00
208_E	219_R	1.206	1.00
27_S	192_V	1.204	1.00
153_S	156_G	1.194	1.00
352_A	356_A	1.192	1.00
227_L	328_V	1.192	1.00
242_K	260_H	1.189	1.00
340_L	344_I	1.188	1.00
199_N	203_I	1.179	1.00
300_Y	328_V	1.178	1.00
270_L	273_Q	1.177	1.00
26_E	30_S	1.175	1.00
247_E	252_T	1.174	1.00
267_D	271_I	1.174	1.00
241_A	284_C	1.172	1.00
259_Y	289_F	1.171	1.00
263_L	267_D	1.168	1.00
381_G	385_T	1.154	1.00
421_R	424_F	1.150	1.00
403_L	407_E	1.149	1.00
111_L	125_L	1.149	1.00
363_E	367_E	1.145	1.00
231_G	302_I	1.144	1.00
419_M	423_S	1.143	1.00
83_R	107_K	1.137	1.00
53_Y	56_D	1.134	1.00
63_S	69_M	1.134	1.00
241_A	245_A	1.132	1.00
45_S	72_Q	1.131	1.00
69_M	86_A	1.129	1.00
246_G	249_K	1.123	1.00
73_V	86_A	1.123	1.00
404_M	407_E	1.123	1.00
384_E	387_A	1.122	1.00
27_S	34_T	1.118	1.00
214_A	218_D	1.113	1.00
221_I	247_E	1.112	1.00
85_A	109_L	1.111	1.00
85_A	99_V	1.110	1.00
213_T	240_W	1.105	1.00
267_D	270_L	1.104	1.00
240_W	243_E	1.100	1.00
249_K	256_A	1.099	1.00
179_L	191_A	1.098	1.00
19_K	23_D	1.097	1.00
154_K	157_Q	1.086	1.00
398_K	402_E	1.082	1.00
401_V	404_M	1.082	1.00
364_K	367_E	1.081	1.00
412_M	416_L	1.071	1.00
28_I	51_P	1.069	1.00
420_H	423_S	1.067	1.00
220_V	233_V	1.064	1.00
157_Q	160_K	1.062	1.00
417_E	421_R	1.058	1.00
413_E	416_L	1.058	1.00
217_I	244_L	1.053	1.00
246_G	250_S	1.053	1.00
225_E	254_S	1.050	1.00
419_M	422_V	1.050	1.00
418_K	421_R	1.050	1.00
22_Q	26_E	1.050	1.00
71_D	294_D	1.049	1.00
231_G	282_V	1.049	1.00
27_S	30_S	1.049	1.00
134_V	168_L	1.048	1.00
94_Q	98_F	1.048	1.00
402_E	406_K	1.048	1.00
371_R	375_D	1.048	1.00
74_Q	77_K	1.047	1.00
179_L	183_M	1.047	1.00
303_H	331_L	1.046	1.00
149_R	153_S	1.043	1.00
415_K	419_M	1.043	1.00
381_G	384_E	1.042	1.00
155_L	158_L	1.042	1.00
182_V	185_L	1.041	1.00
387_A	394_F	1.040	1.00
23_D	27_S	1.038	1.00
59_V	134_V	1.036	1.00
232_I	285_C	1.032	1.00
25_I	50_L	1.031	1.00
361_V	364_K	1.031	1.00
46_L	50_L	1.030	1.00
360_R	365_T	1.023	1.00
215_E	218_D	1.021	1.00
380_Y	385_T	1.021	1.00
230_P	297_D	1.019	1.00
31_G	166_P	1.018	1.00
358_V	361_V	1.013	1.00
213_T	217_I	1.013	1.00
221_I	225_E	1.009	1.00
70_E	269_I	1.003	1.00
352_A	355_I	1.001	1.00
382_V	389_M	1.000	1.00
375_D	379_Q	0.999	1.00
272_Q	295_K	0.993	1.00
188_L	191_A	0.990	1.00
405_K	410_Y	0.988	1.00
385_T	388_R	0.986	1.00
211_A	215_E	0.981	1.00
343_Q	347_M	0.981	1.00
300_Y	330_I	0.980	1.00
222_Q	225_E	0.976	1.00
364_K	368_R	0.972	1.00
222_Q	226_N	0.970	1.00
33_D	189_Q	0.968	1.00
24_I	47_C	0.968	1.00
404_M	408_I	0.961	1.00
229_G	326_P	0.961	1.00
228_Q	231_G	0.959	1.00
68_L	292_G	0.955	1.00
359_I	365_T	0.955	1.00
376_V	379_Q	0.945	1.00
180_Q	184_N	0.944	1.00
414_L	418_K	0.944	1.00
96_R	99_V	0.942	1.00
369_D	372_R	0.936	1.00
57_G	129_P	0.934	1.00
179_L	182_V	0.932	1.00
405_K	408_I	0.932	1.00
274_Q	280_L	0.927	1.00
380_Y	384_E	0.926	1.00
223_L	302_I	0.923	1.00
383_G	387_A	0.922	1.00
360_R	364_K	0.920	1.00
98_F	101_E	0.919	1.00
351_T	355_I	0.916	1.00
35_I	174_A	0.915	1.00
365_T	368_R	0.911	1.00
345_I	348_E	0.911	1.00
359_I	364_K	0.910	1.00
382_V	386_Q	0.909	1.00
410_Y	414_L	0.908	1.00
26_E	54_M	0.907	1.00
363_E	366_E	0.905	1.00
369_D	375_D	0.902	1.00
271_I	283_I	0.902	1.00
203_I	321_G	0.901	1.00
405_K	409_S	0.899	1.00
400_S	404_M	0.898	1.00
407_E	410_Y	0.893	1.00
399_T	403_L	0.890	1.00
374_R	381_G	0.889	1.00
361_V	367_E	0.888	1.00
419_M	425_L	0.886	1.00
181_D	184_N	0.885	1.00
70_E	74_Q	0.883	1.00
124_K	127_S	0.882	1.00
140_C	143_E	0.882	1.00
397_G	401_V	0.878	1.00
391_I	394_F	0.877	1.00
216_K	223_L	0.874	1.00
23_D	26_E	0.868	1.00
356_A	360_R	0.867	1.00
139_H	315_Q	0.866	1.00
418_K	426_L	0.866	1.00
216_K	305_H	0.861	1.00
224_V	254_S	0.861	1.00
376_V	381_G	0.861	1.00
230_P	278_N	0.861	1.00
383_G	386_Q	0.860	1.00
132_L	166_P	0.858	1.00
310_A	342_E	0.854	1.00
309_T	312_A	0.854	1.00
421_R	425_L	0.852	1.00
75_Q	79_R	0.848	1.00
420_H	424_F	0.845	1.00
404_M	410_Y	0.842	1.00
232_I	283_I	0.841	1.00
379_Q	384_E	0.840	1.00
376_V	385_T	0.837	1.00
380_Y	390_M	0.837	1.00
401_V	413_E	0.836	1.00
356_A	359_I	0.835	1.00
12_F	78_A	0.825	1.00
73_V	110_Y	0.824	1.00
399_T	402_E	0.818	1.00
405_K	413_E	0.817	1.00
287_N	316_E	0.809	1.00
384_E	389_M	0.808	1.00
307_P	313_F	0.805	1.00
131_S	165_P	0.804	1.00
386_Q	390_M	0.803	1.00
24_I	36_A	0.802	1.00
373_L	377_L	0.802	1.00
55_L	131_S	0.795	1.00
390_M	394_F	0.795	1.00
124_K	128_V	0.791	1.00
268_R	275_F	0.791	1.00
408_I	412_M	0.791	1.00
88_N	265_S	0.789	1.00
348_E	351_T	0.789	1.00
160_K	163_G	0.788	1.00
374_R	380_Y	0.788	1.00
275_F	283_I	0.785	1.00
47_C	51_P	0.784	1.00
217_I	221_I	0.782	1.00
219_R	223_L	0.781	1.00
307_P	316_E	0.780	1.00
341_Q	344_I	0.777	1.00
71_D	76_L	0.776	1.00
413_E	419_M	0.773	1.00
31_G	55_L	0.773	1.00
52_G	76_L	0.769	1.00
362_L	368_R	0.769	1.00
223_L	300_Y	0.769	1.00
272_Q	275_F	0.767	1.00
387_A	392_H	0.765	1.00
411_R	415_K	0.765	1.00
388_R	392_H	0.764	1.00
370_E	381_G	0.761	1.00
415_K	423_S	0.760	1.00
384_E	388_R	0.756	1.00
61_I	76_L	0.756	1.00
402_E	407_E	0.756	1.00
98_F	102_H	0.754	1.00
358_V	365_T	0.753	1.00
24_I	28_I	0.752	1.00
357_D	363_E	0.749	1.00
350_V	354_E	0.746	1.00
48_Y	51_P	0.746	1.00
182_V	186_L	0.743	1.00
378_L	382_V	0.742	1.00
415_K	424_F	0.742	1.00
351_T	354_E	0.740	1.00
360_R	363_E	0.739	1.00
379_Q	385_T	0.739	1.00
224_V	227_L	0.738	1.00
418_K	425_L	0.736	1.00
340_L	343_Q	0.734	1.00
379_Q	386_Q	0.734	1.00
243_E	247_E	0.734	1.00
164_H	167_V	0.730	1.00
369_D	374_R	0.728	1.00
412_M	419_M	0.728	1.00
410_Y	413_E	0.727	1.00
33_D	167_V	0.725	1.00
385_T	390_M	0.724	1.00
412_M	422_V	0.721	1.00
151_D	154_K	0.720	1.00
422_V	426_L	0.720	1.00
71_D	75_Q	0.719	1.00
423_S	426_L	0.719	1.00
370_E	376_V	0.719	1.00
386_Q	389_M	0.719	1.00
421_R	426_L	0.716	1.00
117_Q	121_V	0.715	1.00
357_D	364_K	0.710	1.00
376_V	384_E	0.709	1.00
133_F	164_H	0.709	1.00
273_Q	276_I	0.709	1.00
155_L	159_R	0.708	1.00
50_L	54_M	0.708	1.00
189_Q	192_V	0.706	1.00
38_L	42_G	0.706	1.00
388_R	393_L	0.703	1.00
386_Q	393_L	0.699	1.00
356_A	361_V	0.698	1.00
203_I	329_S	0.696	1.00
401_V	410_Y	0.694	1.00
358_V	366_E	0.693	1.00
325_K	367_E	0.693	1.00
406_K	410_Y	0.692	1.00
351_T	362_L	0.691	1.00
380_Y	386_Q	0.690	1.00
339_E	343_Q	0.689	1.00
377_L	394_F	0.688	1.00
373_L	376_V	0.687	1.00
397_G	400_S	0.687	1.00
117_Q	151_D	0.686	1.00
48_Y	168_L	0.684	1.00
418_K	422_V	0.682	1.00
379_Q	382_V	0.681	1.00
417_E	420_H	0.680	1.00
362_L	366_E	0.680	1.00
412_M	420_H	0.679	1.00
362_L	367_E	0.679	1.00
377_L	381_G	0.677	1.00
400_S	407_E	0.677	1.00
357_D	367_E	0.677	1.00
358_V	368_R	0.673	1.00
354_E	360_R	0.673	1.00
403_L	406_K	0.670	1.00
35_I	169_A	0.669	1.00
382_V	385_T	0.668	1.00
412_M	418_K	0.667	1.00
402_E	408_I	0.666	1.00
153_S	159_R	0.666	1.00
402_E	405_K	0.665	1.00
388_R	394_F	0.664	1.00
230_P	298_I	0.663	1.00
387_A	393_L	0.662	1.00
369_D	376_V	0.662	1.00
419_M	426_L	0.661	1.00
202_N	326_P	0.659	1.00
265_S	268_R	0.657	1.00
148_F	151_D	0.656	1.00
199_N	202_N	0.654	1.00
371_R	379_Q	0.651	1.00
353_E	357_D	0.650	1.00
407_E	411_R	0.649	1.00
370_E	377_L	0.648	1.00
55_L	166_P	0.647	1.00
411_R	414_L	0.646	1.00
372_R	376_V	0.645	1.00
374_R	379_Q	0.643	1.00
259_Y	288_A	0.642	1.00
231_G	235_C	0.641	1.00
378_L	381_G	0.640	1.00
401_V	409_S	0.640	1.00
177_E	180_Q	0.640	1.00
385_T	391_I	0.639	1.00
389_M	392_H	0.638	1.00
359_I	367_E	0.638	1.00
409_S	412_M	0.638	1.00
350_V	353_E	0.637	1.00
406_K	409_S	0.637	1.00
416_L	420_H	0.637	1.00
327_S	330_I	0.635	1.00
403_L	408_I	0.634	1.00
40_T	172_A	0.633	1.00
36_A	168_L	0.632	1.00
69_M	110_Y	0.631	1.00
149_R	156_G	0.630	1.00
280_L	283_I	0.629	1.00
402_E	410_Y	0.628	1.00
387_A	391_I	0.624	1.00
202_N	205_L	0.622	1.00
363_E	368_R	0.621	1.00
97_Q	101_E	0.621	1.00
381_G	389_M	0.620	1.00
417_E	423_S	0.620	1.00
416_L	426_L	0.619	1.00
397_G	402_E	0.618	1.00
414_L	417_E	0.617	1.00
388_R	391_I	0.617	1.00
354_E	358_V	0.615	1.00
180_Q	183_M	0.614	1.00
370_E	380_Y	0.614	1.00
278_N	297_D	0.611	1.00
356_A	362_L	0.611	1.00
210_A	215_E	0.611	1.00
298_I	320_A	0.610	1.00
172_A	318_G	0.608	1.00
68_L	71_D	0.607	1.00
411_R	421_R	0.605	1.00
381_G	394_F	0.602	1.00
60_L	133_F	0.602	1.00
94_Q	97_Q	0.602	1.00
357_D	362_L	0.600	1.00
411_R	417_E	0.599	1.00
409_S	413_E	0.598	1.00
156_G	159_R	0.598	1.00
357_D	360_R	0.598	1.00
416_L	419_M	0.596	1.00
157_Q	161_K	0.595	1.00
358_V	367_E	0.593	1.00
372_R	375_D	0.593	1.00
397_G	404_M	0.592	1.00
200_R	207_V	0.592	1.00
135_I	142_S	0.590	1.00
65_L	291_M	0.589	1.00
56_D	129_P	0.589	1.00
303_H	307_P	0.583	1.00
115_A	118_S	0.583	1.00
88_N	91_L	0.582	1.00
361_V	368_R	0.581	1.00
397_G	419_M	0.580	1.00
259_Y	263_L	0.580	1.00
224_V	231_G	0.580	1.00
370_E	375_D	0.579	1.00
380_Y	387_A	0.579	1.00
369_D	373_L	0.576	1.00
357_D	365_T	0.576	1.00
381_G	386_Q	0.575	1.00
260_H	263_L	0.575	1.00
378_L	384_E	0.575	1.00
266_G	270_L	0.575	1.00
401_V	407_E	0.574	1.00
411_R	416_L	0.574	1.00
352_A	362_L	0.573	1.00
370_E	374_R	0.572	1.00
48_Y	63_S	0.572	1.00
337_D	340_L	0.571	1.00
62_V	144_W	0.571	1.00
370_E	379_Q	0.570	1.00
408_I	416_L	0.569	1.00
17_F	50_L	0.568	1.00
72_Q	76_L	0.565	1.00
415_K	422_V	0.564	1.00
347_M	351_T	0.564	1.00
211_A	214_A	0.563	1.00
385_T	393_L	0.563	1.00
400_S	412_M	0.561	1.00
25_I	29_L	0.560	1.00
258_F	263_L	0.560	1.00
101_E	157_Q	0.560	1.00
386_Q	391_I	0.560	1.00
399_T	406_K	0.559	1.00
271_I	275_F	0.559	1.00
412_M	423_S	0.559	1.00
204_A	326_P	0.558	1.00
71_D	79_R	0.558	1.00
214_A	217_I	0.557	1.00
402_E	409_S	0.557	1.00
290_G	312_A	0.556	1.00
420_H	426_L	0.555	1.00
413_E	423_S	0.555	1.00
176_K	311_E	0.554	1.00
404_M	413_E	0.553	1.00
385_T	394_F	0.553	1.00
399_T	405_K	0.553	1.00
384_E	390_M	0.552	1.00
132_L	168_L	0.552	1.00
404_M	414_L	0.549	1.00
337_D	341_Q	0.549	1.00
410_Y	415_K	0.548	1.00
415_K	421_R	0.548	1.00
369_D	377_L	0.547	1.00
27_S	32_K	0.547	1.00
258_F	271_I	0.547	1.00
220_V	223_L	0.543	0.99
201_P	205_L	0.541	0.99
411_R	422_V	0.539	0.99
401_V	417_E	0.538	0.99
268_R	272_Q	0.536	0.99
96_R	100_L	0.535	0.99
401_V	416_L	0.535	0.99
401_V	406_K	0.534	0.99
99_V	102_H	0.533	0.99
407_E	417_E	0.533	0.99
286_T	316_E	0.532	0.99
291_M	315_Q	0.532	0.99
213_T	218_D	0.530	0.99
171_T	174_A	0.530	0.99
398_K	401_V	0.529	0.99
410_Y	417_E	0.528	0.99
387_A	390_M	0.528	0.99
398_K	404_M	0.527	0.99
410_Y	416_L	0.526	0.99
374_R	391_I	0.526	0.99
397_G	413_E	0.525	0.99
416_L	422_V	0.525	0.99
352_A	357_D	0.525	0.99
257_D	283_I	0.525	0.99
375_D	381_G	0.524	0.99
198_V	201_P	0.523	0.99
221_I	254_S	0.523	0.99
29_L	55_L	0.523	0.99
336_G	339_E	0.522	0.99
35_I	182_V	0.522	0.99
27_S	190_H	0.522	0.99
154_K	158_L	0.522	0.99
134_V	170_L	0.520	0.99
62_V	141_I	0.520	0.99
399_T	404_M	0.520	0.99
343_Q	346_Q	0.519	0.99
401_V	414_L	0.519	0.99
407_E	413_E	0.518	0.99
236_P	305_H	0.518	0.99
230_P	299_R	0.517	0.99
374_R	385_T	0.516	0.99
176_K	180_Q	0.516	0.99
287_N	312_A	0.515	0.99
269_I	272_Q	0.515	0.99
385_T	389_M	0.514	0.99
117_Q	157_Q	0.514	0.99
342_E	346_Q	0.513	0.99
230_P	275_F	0.513	0.99
217_I	252_T	0.513	0.99
20_G	38_L	0.513	0.99
233_V	302_I	0.513	0.99
404_M	409_S	0.511	0.99
406_K	412_M	0.508	0.99
377_L	390_M	0.508	0.99
384_E	391_I	0.508	0.99
400_S	403_L	0.507	0.99
403_L	410_Y	0.505	0.99
415_K	420_H	0.504	0.99
411_R	425_L	0.504	0.99
395_M	398_K	0.502	0.99
178_T	185_L	0.501	0.99
382_V	388_R	0.500	0.99

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4pxaA	1	0.7198	100	0.335	Contact Map
2db3A	1	0.7117	100	0.34	Contact Map
4w7sA	2	0.756	100	0.351	Contact Map
2v1xA	1	0.9335	100	0.352	Contact Map
1oywA	1	0.8669	100	0.355	Contact Map
4q48A	1	0.7762	100	0.355	Contact Map
4ljyA	1	0.744	100	0.355	Contact Map
4nhoA	1	0.7016	100	0.357	Contact Map
3mwyW	2	0.8105	100	0.358	Contact Map
4d25A	1	0.7117	100	0.363	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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