GREMLIN Database
RIR1 - Ribonucleoside-diphosphate reductase subunit alpha
UniProt: P50620 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 700 (592)
Sequences: 3066 (1014)
Seq/√Len: 41.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
293_R676_H7.9341.00
290_E320_N5.8941.00
452_R456_K4.7521.00
508_K564_F4.6411.00
295_D338_N4.2001.00
297_A338_N4.1251.00
66_E70_S3.9251.00
426_E501_Q3.9151.00
501_Q564_F3.8931.00
297_A336_K3.8101.00
430_K505_E3.8081.00
139_E427_K3.7561.00
433_T461_I3.7081.00
290_E294_E3.6681.00
500_I565_V3.6621.00
465_A492_F3.5451.00
258_I282_V3.3911.00
504_A564_F3.3361.00
485_R643_T3.1171.00
184_R187_D3.0681.00
286_D366_K3.0601.00
480_E627_K2.9511.00
522_Y570_M2.9301.00
295_D340_R2.9231.00
425_I495_V2.9141.00
299_Y332_V2.8971.00
508_K568_H2.8871.00
426_E498_Y2.8801.00
564_F568_H2.8361.00
639_D677_R2.8351.00
188_I450_A2.8201.00
208_A256_R2.8001.00
430_K501_Q2.7121.00
299_Y336_K2.6871.00
639_D673_Y2.6651.00
434_D509_E2.6651.00
263_D345_K2.6231.00
299_Y327_V2.6221.00
635_F673_Y2.6221.00
449_P452_R2.5671.00
486_D490_T2.5621.00
209_K260_D2.5011.00
386_L651_G2.4481.00
433_T575_R2.4401.00
80_V127_L2.4301.00
259_N342_L2.4211.00
476_G625_F2.4111.00
563_A567_E2.3931.00
79_E138_K2.3791.00
559_K562_K2.3661.00
83_T138_K2.3581.00
322_M325_K2.3571.00
453_R457_A2.3501.00
364_V386_L2.3441.00
301_F306_I2.2731.00
338_N341_K2.2381.00
203_L223_V2.1701.00
504_A508_K2.1690.99
259_N335_E2.1380.99
489_N646_Q2.1200.99
371_N521_T2.1100.99
129_F435_S2.1080.99
259_N345_K2.1050.99
557_D560_K2.0730.99
528_F531_Y2.0610.99
480_E484_A2.0470.99
434_D502_R2.0070.99
259_N337_I2.0040.99
529_D562_K1.9830.99
504_A568_H1.9530.99
673_Y677_R1.9430.99
300_V337_I1.9400.99
620_S624_F1.9370.99
332_V336_K1.9350.99
426_E497_F1.9030.99
412_G432_A1.9010.99
559_K563_A1.8770.99
176_N181_D1.8590.98
325_K329_N1.8500.98
180_N187_D1.8470.98
289_V360_F1.8440.98
286_D675_H1.8330.98
149_Y412_G1.8290.98
227_M275_V1.8220.98
528_F562_K1.8190.98
484_A640_M1.8090.98
500_I570_M1.8070.98
419_V428_T1.7900.98
485_R640_M1.7820.98
183_S190_M1.7470.98
337_I342_L1.7310.97
526_E530_K1.7210.97
386_L681_T1.7010.97
148_E424_S1.6950.97
560_K564_F1.6940.97
430_K502_R1.6840.97
313_H371_N1.6810.97
284_I358_I1.6750.97
517_Y566_A1.6730.97
363_N366_K1.6700.97
504_A561_L1.6560.97
471_Y491_F1.6490.97
88_K145_I1.6370.96
287_K290_E1.6240.96
92_P122_I1.6150.96
231_D277_T1.6090.96
347_A667_L1.6010.96
385_V577_C1.5880.96
224_V264_T1.5840.96
291_L296_K1.5710.95
324_D328_D1.5670.95
406_D448_A1.5570.95
315_D321_E1.5540.95
499_S575_R1.5410.95
449_P453_R1.5330.95
83_T142_N1.5250.95
130_A140_Y1.5110.94
501_Q561_L1.5100.94
188_I406_D1.5100.94
528_F532_V1.5050.94
183_S229_L1.5040.94
432_A463_L1.4940.94
291_L299_Y1.4920.94
638_V677_R1.4890.94
123_S141_V1.4840.94
83_T123_S1.4810.94
127_L137_A1.4790.94
138_K142_N1.4750.94
80_V123_S1.4690.94
364_V681_T1.4670.93
563_A566_A1.4630.93
489_N643_T1.4630.93
502_R505_E1.4530.93
561_L564_F1.4520.93
305_T333_K1.4510.93
291_L327_V1.4450.93
183_S233_A1.4430.93
457_A515_D1.4370.93
175_V185_A1.4310.93
140_Y435_S1.4210.92
422_H494_M1.4210.92
527_Y565_V1.4170.92
123_S127_L1.4160.92
497_F561_L1.4100.92
153_T246_S1.4020.92
133_D438_H1.3980.92
227_M278_L1.3960.92
117_R120_D1.3850.91
437_T510_K1.3830.91
473_A597_I1.3720.91
364_V651_G1.3670.91
264_T275_V1.3600.91
312_Q322_M1.3530.90
490_T555_T1.3510.90
258_I342_L1.3480.90
177_D207_R1.3460.90
361_Q375_K1.3430.90
330_P333_K1.3320.90
480_E636_K1.3290.90
496_N500_I1.3210.89
477_I487_F1.3180.89
406_D450_A1.3150.89
642_A677_R1.3110.89
421_E424_S1.3080.89
637_V654_F1.2980.88
174_E202_N1.2860.88
189_S201_L1.2780.88
167_L442_T1.2750.87
65_E68_F1.2720.87
125_V156_F1.2710.87
505_E564_F1.2580.87
620_S623_W1.2490.86
309_E331_R1.2480.86
422_H487_F1.2440.86
187_D191_Q1.2390.86
320_N324_D1.2390.86
142_N146_N1.2370.86
198_G384_E1.2370.86
100_F105_A1.2360.86
143_L428_T1.2350.86
208_A302_Y1.2350.86
504_A565_V1.2310.86
476_G621_N1.2280.85
69_L72_Y1.2230.85
430_K498_Y1.2220.85
123_S137_A1.2110.85
504_A517_Y1.1980.84
457_A516_Q1.1970.84
69_L74_F1.1970.84
101_Y105_A1.1950.84
426_E430_K1.1880.83
311_G314_M1.1860.83
479_Y593_S1.1810.83
141_V145_I1.1790.83
194_K237_A1.1780.83
529_D532_V1.1770.83
186_I229_L1.1770.83
522_Y527_Y1.1700.82
370_N514_F1.1700.82
84_A141_V1.1700.82
177_D182_I1.1650.82
251_L255_H1.1630.82
211_E304_H1.1620.82
489_N647_H1.1610.82
234_F247_G1.1540.82
414_L429_V1.1510.81
122_I144_M1.1500.81
656_L674_A1.1490.81
468_L488_A1.1490.81
424_S427_K1.1450.81
208_A211_E1.1380.81
186_I233_A1.1350.81
198_G380_N1.1340.80
301_F332_V1.1310.80
501_Q560_K1.1210.80
253_I292_A1.1200.80
437_T571_Y1.1200.80
79_E135_E1.1170.79
80_V83_T1.1140.79
517_Y528_F1.1120.79
478_A625_F1.1090.79
182_I207_R1.1080.79
290_E293_R1.1080.79
420_M471_Y1.1080.79
359_M364_V1.1060.79
565_V570_M1.1040.79
496_N576_L1.0990.78
635_F639_D1.0970.78
293_R672_L1.0960.78
438_H510_K1.0940.78
123_S138_K1.0920.78
483_E486_D1.0920.78
513_T517_Y1.0920.78
287_K320_N1.0870.78
315_D320_N1.0790.77
108_T113_K1.0690.76
518_E523_A1.0680.76
645_Q652_I1.0660.76
289_V672_L1.0650.76
413_S584_I1.0640.76
198_G382_C1.0590.76
350_R671_D1.0570.76
517_Y522_Y1.0570.76
373_I516_Q1.0530.75
170_C198_G1.0510.75
439_V461_I1.0510.75
485_R636_K1.0490.75
80_V138_K1.0490.75
494_M498_Y1.0440.75
124_I160_G1.0400.74
488_A644_I1.0390.74
562_K566_A1.0360.74
78_K82_K1.0360.74
656_L670_I1.0360.74
669_R672_L1.0340.74
522_Y562_K1.0330.74
309_E314_M1.0320.74
467_N470_G1.0310.74
385_V650_Q1.0270.73
170_C411_L1.0250.73
674_A682_I1.0190.73
519_G523_A1.0190.73
308_K326_F1.0190.73
282_V346_L1.0170.73
133_D434_D1.0170.73
491_F495_V1.0130.72
465_A495_V1.0080.72
336_K567_E1.0060.72
119_E145_I1.0030.72
494_M557_D1.0000.71
153_T169_S1.0000.71
513_T518_E0.9990.71
497_F557_D0.9980.71
91_F147_Q0.9980.71
250_Y281_G0.9980.71
228_K274_R0.9970.71
170_C382_C0.9950.71
180_N184_R0.9940.71
292_A340_R0.9910.71
505_E508_K0.9910.71
128_F165_G0.9910.71
638_V642_A0.9870.70
673_Y676_H0.9860.70
289_V292_A0.9840.70
635_F669_R0.9820.70
425_I491_F0.9760.70
229_L232_N0.9740.69
593_S657_F0.9740.69
253_I285_P0.9730.69
374_S388_A0.9700.69
316_E320_N0.9650.69
371_N530_K0.9640.69
149_Y432_A0.9600.68
426_E505_E0.9580.68
85_Y88_K0.9580.68
416_I465_A0.9560.68
313_H366_K0.9560.68
498_Y501_Q0.9560.68
371_N524_T0.9550.68
321_E325_K0.9550.68
170_C243_R0.9540.68
296_K338_N0.9450.67
198_G243_R0.9450.67
264_T280_I0.9430.67
312_Q316_E0.9430.67
360_F674_A0.9390.66
482_P486_D0.9360.66
203_L230_L0.9360.66
423_K426_E0.9360.66
147_Q588_Q0.9350.66
556_E560_K0.9330.66
223_V251_L0.9320.66
429_V498_Y0.9300.66
302_Y305_T0.9250.65
308_K322_M0.9230.65
582_G655_T0.9190.65
527_Y570_M0.9190.65
170_C384_E0.9170.65
86_A120_D0.9100.64
88_K142_N0.9080.64
286_D363_N0.9040.64
65_E70_S0.9030.63
494_M556_E0.9010.63
228_K232_N0.8960.63
227_M264_T0.8950.63
74_F78_K0.8940.63
500_I522_Y0.8920.62
89_F119_E0.8900.62
638_V656_L0.8870.62
329_N332_V0.8810.61
472_L484_A0.8790.61
463_L584_I0.8750.61
439_V463_L0.8750.61
258_I300_V0.8720.61
518_E567_E0.8720.61
659_K689_D0.8720.61
591_T597_I0.8720.61
67_E131_N0.8700.61
289_V675_H0.8680.60
457_A519_G0.8670.60
382_C411_L0.8650.60
287_K324_D0.8640.60
243_R382_C0.8620.60
202_N252_N0.8620.60
495_V576_L0.8610.60
372_H514_F0.8600.60
62_Q69_L0.8590.60
470_G590_S0.8570.59
500_I527_Y0.8560.59
76_D134_T0.8560.59
363_N367_V0.8550.59
178_S181_D0.8530.59
619_A622_N0.8530.59
126_A159_A0.8500.59
82_K85_Y0.8480.59
485_R489_N0.8470.58
78_K85_Y0.8450.58
292_A339_P0.8440.58
492_F648_I0.8420.58
504_A570_M0.8420.58
180_N191_Q0.8380.58
251_L261_F0.8380.58
487_F491_F0.8360.57
559_K566_A0.8340.57
154_P169_S0.8290.57
380_N384_E0.8280.57
315_D366_K0.8270.57
500_I504_A0.8250.56
85_Y119_E0.8230.56
637_V657_F0.8230.56
197_G245_G0.8230.56
85_Y90_R0.8210.56
294_E676_H0.8210.56
551_H554_T0.8200.56
383_S683_Y0.8200.56
525_G558_W0.8170.56
418_N474_Q0.8170.56
309_E329_N0.8160.56
154_P243_R0.8150.55
581_T585_S0.8130.55
651_G681_T0.8120.55
179_L190_M0.8110.55
420_M475_N0.8100.55
658_L666_D0.8080.55
472_L477_I0.8070.55
470_G591_T0.8040.54
324_D327_V0.8030.54
429_V499_S0.8020.54
422_H491_F0.8020.54
133_D510_K0.8000.54
473_A625_F0.7990.54
372_H519_G0.7990.54
407_I460_S0.7980.54
420_M474_Q0.7960.54
341_K344_E0.7950.54
600_R628_E0.7900.53
283_V361_Q0.7900.53
98_F102_N0.7890.53
198_G653_S0.7890.53
198_G411_L0.7890.53
490_T553_P0.7880.53
441_E571_Y0.7840.53
266_K274_R0.7830.53
322_M326_F0.7830.53
619_A628_E0.7830.53
204_S310_Y0.7820.52
471_Y487_F0.7820.52
521_T526_E0.7820.52
281_G357_Y0.7800.52
367_V531_Y0.7780.52
143_L148_E0.7770.52
485_R639_D0.7760.52
380_N580_P0.7750.52
267_I273_V0.7740.52
63_Y72_Y0.7730.52
367_V530_K0.7720.51
508_K517_Y0.7710.51
634_M637_V0.7690.51
70_S74_F0.7680.51
425_I429_V0.7680.51
186_I230_L0.7670.51
411_L462_G0.7650.51
658_L670_I0.7640.51
265_K355_Y0.7640.51
79_E82_K0.7630.51
221_K238_D0.7620.51
295_D567_E0.7620.51
184_R450_A0.7600.50
281_G355_Y0.7600.50
262_L357_Y0.7600.50
644_I652_I0.7600.50
384_E411_L0.7590.50
77_I81_F0.7570.50
669_R673_Y0.7570.50
249_A278_L0.7570.50
521_T530_K0.7570.50
416_I495_V0.7540.50
253_I282_V0.7540.50
151_P435_S0.7510.50
284_I506_I0.7510.50
64_Y68_F0.7510.50
426_E494_M0.7510.50
265_K280_I0.7490.49
517_Y561_L0.7480.49
82_K87_K0.7460.49
198_G580_P0.7450.49
69_L433_T0.7440.49
254_F319_M0.7440.49
477_I485_R0.7430.49
167_L434_D0.7420.49
60_E78_K0.7410.49
344_E668_N0.7410.49
466_M581_T0.7410.49
191_Q194_K0.7390.48
122_I150_Q0.7380.48
517_Y570_M0.7370.48
291_L339_P0.7360.48
212_A304_H0.7360.48
78_K81_F0.7350.48
560_K567_E0.7330.48
210_G214_K0.7320.48
340_R344_E0.7280.47
79_E83_T0.7280.47
641_I652_I0.7280.47
518_E566_A0.7260.47
618_L622_N0.7260.47
343_L672_L0.7260.47
439_V443_T0.7250.47
203_L249_A0.7230.47
126_A215_D0.7220.47
196_G220_T0.7220.47
497_F558_W0.7200.47
667_L684_Y0.7200.47
578_I648_I0.7200.47
243_R380_N0.7190.47
638_V679_I0.7190.47
193_S238_D0.7180.46
152_S169_S0.7170.46
430_K564_F0.7170.46
78_K518_E0.7170.46
132_G137_A0.7160.46
530_K646_Q0.7150.46
480_E640_M0.7140.46
338_N568_H0.7130.46
380_N653_S0.7120.46
76_D79_E0.7100.46
170_C380_N0.7090.46
211_E302_Y0.7080.46
452_R562_K0.7070.45
252_N361_Q0.7070.45
471_Y475_N0.7070.45
70_S75_E0.7060.45
629_A657_F0.7060.45
200_S342_L0.7060.45
641_I654_F0.7040.45
672_L676_H0.7030.45
310_Y314_M0.7020.45
170_C653_S0.7010.45
171_F197_G0.7000.45
507_A569_G0.7000.45
570_M575_R0.6980.45
139_E430_K0.6970.44
86_A117_R0.6960.44
474_Q617_G0.6960.44
562_K570_M0.6950.44
313_H316_E0.6950.44
479_Y637_V0.6920.44
75_E78_K0.6910.44
422_H490_T0.6910.44
528_F552_I0.6900.44
275_V278_L0.6890.44
146_N424_S0.6890.44
368_H376_V0.6880.44
131_N442_T0.6870.44
369_A574_Y0.6860.43
429_V491_F0.6860.43
417_L474_Q0.6840.43
388_A573_S0.6830.43
660_D688_K0.6820.43
121_R125_V0.6810.43
300_V342_L0.6810.43
643_T646_Q0.6810.43
122_I145_I0.6800.43
369_A388_A0.6790.43
527_Y531_Y0.6790.43
213_I217_E0.6770.43
65_E69_L0.6770.43
243_R384_E0.6760.43
416_I471_Y0.6750.42
253_I262_L0.6750.42
437_T513_T0.6740.42
342_L568_H0.6740.42
360_F671_D0.6730.42
205_K377_K0.6710.42
72_Y76_D0.6710.42
420_M424_S0.6700.42
423_K518_E0.6700.42
266_K352_E0.6690.42
410_N440_S0.6660.42
202_N310_Y0.6660.42
434_D438_H0.6630.41
415_N588_Q0.6630.41
627_K632_M0.6620.41
119_E141_V0.6620.41
221_K265_K0.6610.41
201_L247_G0.6600.41
147_Q418_N0.6590.41
342_L346_L0.6590.41
129_F155_T0.6580.41
496_N528_F0.6570.41
60_E563_A0.6570.41
501_Q504_A0.6560.41
179_L237_A0.6560.41
611_T615_M0.6560.41
531_Y645_Q0.6560.41
595_M655_T0.6550.41
250_Y379_S0.6550.41
438_H509_E0.6540.41
413_S579_A0.6530.40
206_L226_V0.6530.40
633_D670_I0.6530.40
154_P382_C0.6520.40
284_I287_K0.6510.40
505_E568_H0.6500.40
72_Y433_T0.6500.40
563_A656_L0.6490.40
107_K209_K0.6470.40
480_E624_F0.6460.40
166_E443_T0.6460.40
229_L445_I0.6450.40
150_Q588_Q0.6450.40
129_F442_T0.6440.40
189_S412_G0.6440.40
61_N65_E0.6440.40
154_P170_C0.6440.40
527_Y562_K0.6420.39
100_F587_V0.6400.39
128_F159_A0.6390.39
632_M636_K0.6380.39
497_F501_Q0.6380.39
482_P639_D0.6370.39
60_E66_E0.6370.39
477_I639_D0.6360.39
223_V227_M0.6360.39
492_F644_I0.6350.39
85_Y142_N0.6350.39
285_P292_A0.6350.39
215_D234_F0.6350.39
408_S455_N0.6350.39
79_E508_K0.6340.39
113_K423_K0.6310.38
89_F141_V0.6300.38
206_L221_K0.6300.38
122_I156_F0.6280.38
235_R238_D0.6280.38
309_E326_F0.6280.38
458_M573_S0.6280.38
433_T495_V0.6280.38
414_L495_V0.6270.38
477_I638_V0.6270.38
358_I671_D0.6270.38
572_H575_R0.6260.38
64_Y72_Y0.6260.38
69_L77_I0.6260.38
60_E63_Y0.6260.38
226_V236_Y0.6250.38
467_N591_T0.6250.38
434_D510_K0.6240.38
498_Y502_R0.6240.38
64_Y69_L0.6230.38
551_H555_T0.6220.38
288_F298_A0.6210.38
500_I649_D0.6200.38
379_S386_L0.6200.38
320_N483_E0.6200.38
405_L457_A0.6200.38
459_K572_H0.6190.37
254_F301_F0.6190.37
63_Y66_E0.6190.37
473_A616_P0.6190.37
277_T583_S0.6190.37
382_C580_P0.6180.37
458_M516_Q0.6180.37
159_A463_L0.6160.37
365_N376_V0.6160.37
597_I632_M0.6150.37
107_K114_I0.6150.37
494_M552_I0.6140.37
144_M237_A0.6120.37
610_K613_Y0.6110.37
66_E69_L0.6110.37
634_M670_I0.6110.37
155_T439_V0.6090.37
463_L499_S0.6080.36
290_E518_E0.6080.36
384_E580_P0.6070.36
371_N526_E0.6070.36
196_G215_D0.6060.36
495_V648_I0.6060.36
460_S573_S0.6060.36
585_S593_S0.6050.36
409_C462_G0.6050.36
223_V255_H0.6050.36
424_S453_R0.6050.36
105_A121_R0.6040.36
580_P653_S0.6040.36
113_K117_R0.6030.36
506_I572_H0.6030.36
170_C409_C0.6030.36
158_N168_V0.6020.36
292_A672_L0.6010.36
321_E328_D0.6010.36
307_Y326_F0.6000.36
581_T584_I0.6000.36
221_K225_G0.6000.36
213_I257_D0.5990.36
61_N70_S0.5990.36
248_A265_K0.5980.36
113_K486_D0.5980.36
139_E142_N0.5980.36
110_D294_E0.5970.36
561_L570_M0.5970.36
297_A337_I0.5970.36
266_K345_K0.5960.35
271_E274_R0.5960.35
70_S78_K0.5960.35
142_N427_K0.5950.35
100_F121_R0.5950.35
196_G241_G0.5940.35
668_N672_L0.5940.35
250_Y283_V0.5930.35
275_V280_I0.5930.35
387_Q649_D0.5930.35
226_V584_I0.5930.35
218_N240_M0.5920.35
514_F522_Y0.5900.35
279_S355_Y0.5900.35
139_E431_L0.5900.35
74_F431_L0.5900.35
265_K275_V0.5890.35
312_Q325_K0.5880.35
350_R667_L0.5870.35
135_E483_E0.5870.35
66_E162_K0.5860.35
253_I342_L0.5860.35
181_D185_A0.5850.35
577_C683_Y0.5840.34
158_N194_K0.5830.34
662_M666_D0.5810.34
423_K556_E0.5810.34
265_K385_V0.5810.34
423_K427_K0.5810.34
129_F439_V0.5800.34
490_T493_M0.5780.34
148_E428_T0.5780.34
291_L324_D0.5780.34
350_R684_Y0.5770.34
381_L684_Y0.5770.34
200_S467_N0.5770.34
514_F519_G0.5760.34
608_N690_T0.5760.34
248_A357_Y0.5760.34
308_K311_G0.5750.34
414_L428_T0.5740.34
67_E70_S0.5730.34
95_M192_L0.5720.33
79_E85_Y0.5720.33
577_C650_Q0.5710.33
291_L319_M0.5700.33
316_E321_E0.5680.33
252_N283_V0.5680.33
309_E313_H0.5670.33
203_L227_M0.5660.33
130_A137_A0.5660.33
312_Q326_F0.5660.33
469_H585_S0.5660.33
134_T138_K0.5660.33
555_T559_K0.5650.33
287_K291_L0.5650.33
466_M586_Y0.5650.33
585_S592_A0.5640.33
213_I245_G0.5640.33
360_F679_I0.5640.33
382_C409_C0.5630.33
553_P557_D0.5620.33
295_D620_S0.5620.33
283_V359_M0.5610.33
253_I561_L0.5610.33
74_F77_I0.5610.33
497_F560_K0.5600.32
246_S415_N0.5580.32
296_K567_E0.5570.32
69_L87_K0.5570.32
286_D290_E0.5560.32
80_V88_K0.5560.32
235_R277_T0.5560.32
90_R676_H0.5550.32
61_N69_L0.5550.32
405_L458_M0.5550.32
379_S650_Q0.5550.32
330_P334_K0.5540.32
478_A627_K0.5540.32
513_T570_M0.5540.32
127_L138_K0.5530.32
619_A623_W0.5520.32
433_T463_L0.5510.32
426_E556_E0.5500.32
221_K240_M0.5490.32
132_G442_T0.5470.31
191_Q195_L0.5470.31
550_M553_P0.5470.31
616_P649_D0.5470.31
170_C462_G0.5470.31
264_T278_L0.5470.31
122_I141_V0.5460.31
488_A640_M0.5460.31
383_S681_T0.5460.31
297_A327_V0.5440.31
98_F101_Y0.5430.31
191_Q242_Q0.5430.31
185_A230_L0.5430.31
87_K117_R0.5430.31
408_S443_T0.5420.31
306_I433_T0.5420.31
247_G591_T0.5410.31
563_A568_H0.5400.31
381_L683_Y0.5400.31
95_M586_Y0.5390.31
386_L679_I0.5390.31
85_Y146_N0.5390.31
168_V410_N0.5390.31
479_Y634_M0.5380.31
175_V488_A0.5370.31
347_A664_T0.5370.31
524_T570_M0.5370.31
466_M590_S0.5360.30
521_T524_T0.5350.30
296_K449_P0.5350.30
296_K341_K0.5350.30
91_F449_P0.5340.30
561_L569_G0.5340.30
525_G531_Y0.5340.30
387_Q650_Q0.5330.30
560_K568_H0.5330.30
63_Y69_L0.5320.30
423_K474_Q0.5320.30
294_E366_K0.5320.30
139_E563_A0.5310.30
78_K328_D0.5310.30
189_S230_L0.5310.30
386_L584_I0.5310.30
460_S574_Y0.5300.30
74_F82_K0.5300.30
177_D222_G0.5300.30
78_K90_R0.5290.30
220_T628_E0.5290.30
427_K559_K0.5290.30
453_R515_D0.5280.30
585_S603_E0.5280.30
316_E325_K0.5280.30
219_A294_E0.5270.30
508_K567_E0.5270.30
453_R563_A0.5270.30
105_A122_I0.5260.30
170_C580_P0.5260.30
321_E486_D0.5250.30
193_S239_Q0.5250.30
513_T564_F0.5240.30
78_K452_R0.5240.30
232_N235_R0.5240.30
248_A279_S0.5240.30
290_E676_H0.5240.30
306_I326_F0.5240.30
247_G278_L0.5230.29
135_E621_N0.5220.29
437_T572_H0.5220.29
220_T496_N0.5220.29
155_T436_L0.5220.29
60_E74_F0.5220.29
172_L378_F0.5220.29
648_I652_I0.5210.29
269_A272_D0.5210.29
650_Q683_Y0.5200.29
125_V129_F0.5200.29
380_N411_L0.5190.29
658_L662_M0.5190.29
412_G532_V0.5190.29
104_Y382_C0.5190.29
328_D423_K0.5180.29
505_E567_E0.5180.29
202_N205_K0.5180.29
301_F331_R0.5170.29
83_T87_K0.5170.29
154_P354_G0.5170.29
160_G420_M0.5170.29
384_E409_C0.5170.29
579_A671_D0.5170.29
688_K692_Q0.5170.29
253_I258_I0.5160.29
476_G564_F0.5160.29
294_E297_A0.5150.29
155_T407_I0.5150.29
382_C462_G0.5150.29
525_G529_D0.5130.29
97_A461_I0.5130.29
290_E452_R0.5120.29
346_L358_I0.5120.29
526_E529_D0.5110.29
189_S246_S0.5110.29
64_Y67_E0.5110.29
294_E328_D0.5100.28
93_S244_Q0.5100.28
198_G246_S0.5100.28
172_L460_S0.5090.28
309_E312_Q0.5090.28
177_D241_G0.5090.28
243_R580_P0.5080.28
603_E632_M0.5080.28
82_K86_A0.5080.28
125_V433_T0.5060.28
482_P508_K0.5060.28
60_E67_E0.5060.28
423_K513_T0.5060.28
241_G245_G0.5060.28
103_D236_Y0.5050.28
130_A432_A0.5050.28
180_N499_S0.5050.28
87_K146_N0.5050.28
659_K688_K0.5050.28
496_N647_H0.5050.28
216_V573_S0.5040.28
511_G571_Y0.5040.28
307_Y313_H0.5040.28
319_M322_M0.5030.28
611_T614_P0.5030.28
321_E324_D0.5020.28
641_I683_Y0.5020.28
147_Q415_N0.5020.28
151_P463_L0.5020.28
250_Y383_S0.5010.28
65_E72_Y0.5000.28
319_M323_Y0.5000.28
244_Q282_V0.5000.28
155_T159_A0.5000.28
72_Y75_E0.5000.28
116_E558_W0.5000.28
279_S357_Y0.5000.28
492_F583_S0.5000.28
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2xapA 4 0.9429 100 0.116 Contact Map
1peqA 2 0.9429 100 0.116 Contact Map
3hncA 2 0.9243 100 0.123 Contact Map
3k8tA 2 0.8543 100 0.131 Contact Map
2wghA 2 0.88 100 0.149 Contact Map
3o0qA 2 0.7671 100 0.25 Contact Map
1l1lA 1 0.7143 100 0.439 Contact Map
4u3eA 2 0.7657 99.8 0.909 Contact Map
1h7bA 2 0.6157 95.4 0.972 Contact Map
3op6A 2 0.2057 20.4 0.987 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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