SYR - BACSU - GREMLIN Contacts

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SYR - Arginine--tRNA ligase

UniProt:	P46906	Sequences: MNIAEQMKDVLKEEIKAAVLKAGLAEESQIPNVVLETPKDKTHGDYSTNMAMQLARVAKKAPRQIAEEIVAHFDKGKASIEKLDIAGPGFINFYMNNQYLTKLIPSVLEAGEAYGETNIGNGERVQVEFVSANPTGDLHLGHARGAAVGDSLCNVLSKAGYDVSREYYINDAGNQINNLALSVEVRYFEALGLEKPMPEDGYRGEDIIAIGKRLAEEYGDRFVNEEESERLAFFREYGLKYELEKLRKDLENFRVPFDVWYSETSLYQNGKIDKALEALREKGHVYEEDGATWFRSTTFGDDKDRVLIKKDGTYTYLLPDIAYHKDKLDRGFDKLINVWGADHHGYIPRMKAAIEALGYEKGTLEVEIIQLVHLYKNGEKMKMSKRTGKAVTMRDLIEEVGLDAVRYFFAMRSADTHMDFDLDLAVSTSNENPVYYAQYAHARICSMLRQGEEQGLKPAADLDFSHIQSEKEYDLLKTIGGFPEAVAEAAEKRIPHRVTNYIYDLASALHSFYNAEKVIDPENEEKSRARLALMKATQITLNNALQLIGVSAPEKM	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	556 (532)
Sequences:	4630 (2959)
Seq/√Len:	128.3

ECOLI - SYR
BACSU - SYR
HALSA - SYR
SULSO - SYR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
124_R	162_D	5.460	1.00
502_I	544_A	5.431	1.00
277_E	281_E	5.356	1.00
67_E	71_A	4.683	1.00
61_A	64_Q	4.577	1.00
82_K	94_Y	4.272	1.00
157_S	165_R	3.842	1.00
60_K	68_E	3.458	1.00
278_A	282_K	3.342	1.00
107_V	479_I	3.238	1.00
252_N	398_E	3.232	1.00
478_T	508_A	3.153	1.00
155_V	547_L	3.003	1.00
280_R	292_T	2.982	1.00
444_I	534_M	2.936	1.00
113_A	116_E	2.826	1.00
123_E	334_K	2.760	1.00
70_V	91_I	2.746	1.00
277_E	280_R	2.659	1.00
273_D	277_E	2.659	1.00
60_K	64_Q	2.645	1.00
81_E	96_N	2.636	1.00
153_C	165_R	2.607	1.00
325_K	329_D	2.599	1.00
63_R	87_G	2.552	1.00
64_Q	67_E	2.409	1.00
251_E	256_P	2.407	1.00
445_C	538_Q	2.392	1.00
116_E	158_K	2.361	1.00
21_K	72_H	2.338	1.00
518_V	534_M	2.302	1.00
482_F	543_N	2.282	1.00
249_D	394_R	2.263	1.00
441_H	552_A	2.238	1.00
441_H	542_N	2.235	1.00
185_V	217_E	2.209	1.00
224_N	227_E	2.209	1.00
478_T	481_G	2.165	1.00
274_K	329_D	2.159	1.00
539_I	543_N	2.151	1.00
123_E	333_D	2.129	1.00
247_R	251_E	2.100	1.00
501_Y	505_L	2.041	1.00
517_K	520_D	1.999	1.00
220_D	224_N	1.995	1.00
449_R	554_E	1.995	1.00
159_A	490_A	1.983	1.00
278_A	325_K	1.978	1.00
280_R	308_I	1.958	1.00
97_N	473_Y	1.938	1.00
535_K	538_Q	1.923	1.00
445_C	554_E	1.919	1.00
441_H	445_C	1.918	1.00
486_V	547_L	1.915	1.00
240_K	244_E	1.910	1.00
339_W	347_I	1.910	1.00
509_L	534_M	1.899	1.00
407_Y	503_Y	1.879	1.00
324_H	354_I	1.858	1.00
264_T	268_Q	1.837	1.00
489_A	498_V	1.835	1.00
280_R	287_E	1.833	1.00
84_D	94_Y	1.823	1.00
212_K	216_E	1.821	1.00
466_H	526_K	1.817	1.00
102_K	105_P	1.808	1.00
158_K	482_F	1.800	1.00
158_K	543_N	1.799	1.00
127_V	153_C	1.797	1.00
286_Y	295_R	1.782	1.00
352_A	355_E	1.767	1.00
118_N	121_N	1.767	1.00
441_H	538_Q	1.759	1.00
46_Y	95_M	1.746	1.00
287_E	292_T	1.734	1.00
151_S	154_N	1.730	1.00
355_E	363_T	1.722	1.00
472_E	530_R	1.710	1.00
284_H	299_F	1.704	1.00
150_D	154_N	1.704	1.00
295_R	298_T	1.700	1.00
451_G	531_L	1.694	1.00
324_H	337_N	1.693	1.00
278_A	281_E	1.692	1.00
18_A	22_A	1.688	1.00
274_K	277_E	1.684	1.00
524_E	527_S	1.677	1.00
447_M	534_M	1.666	1.00
60_K	65_I	1.656	1.00
117_T	159_A	1.654	1.00
478_T	504_D	1.650	1.00
481_G	484_E	1.644	1.00
228_S	232_A	1.642	1.00
328_L	335_L	1.638	1.00
124_R	164_S	1.633	1.00
446_S	449_R	1.629	1.00
158_K	547_L	1.615	1.00
147_A	253_F	1.614	1.00
280_R	285_V	1.613	1.00
449_R	555_K	1.612	1.00
367_E	493_R	1.604	1.00
159_A	486_V	1.600	1.00
127_V	152_L	1.595	1.00
520_D	527_S	1.594	1.00
154_N	546_Q	1.570	1.00
126_Q	335_L	1.565	1.00
68_E	71_A	1.564	1.00
81_E	97_N	1.554	1.00
285_V	292_T	1.553	1.00
351_K	366_V	1.542	1.00
206_D	210_I	1.537	1.00
525_E	528_R	1.528	1.00
538_Q	542_N	1.522	1.00
473_Y	477_K	1.521	1.00
447_M	518_V	1.511	1.00
469_S	472_E	1.508	1.00
164_S	259_V	1.507	1.00
120_G	161_Y	1.497	1.00
512_F	516_E	1.495	1.00
63_R	67_E	1.482	1.00
261_Y	326_D	1.475	1.00
122_G	161_Y	1.472	1.00
342_D	382_K	1.469	1.00
360_E	363_T	1.468	1.00
479_I	540_T	1.467	1.00
267_Y	319_P	1.459	1.00
70_V	85_I	1.458	1.00
184_E	229_E	1.457	1.00
41_K	474_D	1.446	1.00
524_E	528_R	1.436	1.00
326_D	330_R	1.434	1.00
469_S	516_E	1.421	1.00
254_R	551_S	1.416	1.00
285_V	307_L	1.411	1.00
116_E	157_S	1.410	1.00
475_L	537_T	1.405	1.00
334_K	365_E	1.403	1.00
167_Y	246_L	1.391	1.00
104_I	108_L	1.383	1.00
208_I	212_K	1.381	1.00
108_L	535_K	1.378	1.00
203_R	206_D	1.377	1.00
252_N	397_I	1.369	1.00
463_D	525_E	1.369	1.00
203_R	207_I	1.363	1.00
216_E	220_D	1.347	1.00
156_L	490_A	1.347	1.00
271_K	274_K	1.342	1.00
145_G	371_L	1.337	1.00
502_I	541_L	1.335	1.00
397_I	405_V	1.333	1.00
130_V	250_L	1.329	1.00
482_F	544_A	1.315	1.00
307_L	321_I	1.315	1.00
487_A	491_E	1.311	1.00
309_K	313_T	1.311	1.00
512_F	537_T	1.305	1.00
271_K	326_D	1.305	1.00
130_V	146_A	1.299	1.00
470_E	474_D	1.299	1.00
422_L	426_V	1.298	1.00
213_R	216_E	1.295	1.00
19_V	23_G	1.291	1.00
156_L	493_R	1.288	1.00
347_I	368_I	1.285	1.00
440_A	510_H	1.281	1.00
517_K	521_P	1.277	1.00
519_I	527_S	1.275	1.00
207_I	210_I	1.270	1.00
17_A	21_K	1.262	1.00
104_I	536_A	1.259	1.00
70_V	74_D	1.254	1.00
292_T	308_I	1.253	1.00
226_E	229_E	1.253	1.00
471_K	515_A	1.251	1.00
235_R	240_K	1.238	1.00
108_L	532_A	1.230	1.00
341_A	370_Q	1.230	1.00
479_I	537_T	1.227	1.00
35_L	46_Y	1.224	1.00
482_F	486_V	1.223	1.00
403_D	438_Q	1.220	0.99
355_E	361_K	1.218	0.99
244_E	247_R	1.217	0.99
272_I	319_P	1.214	0.99
545_L	550_V	1.214	0.99
488_E	492_K	1.212	0.99
155_V	489_A	1.207	0.99
526_K	530_R	1.204	0.99
275_A	325_K	1.202	0.99
498_V	544_A	1.202	0.99
221_R	230_R	1.201	0.99
407_Y	432_N	1.199	0.99
248_K	252_N	1.199	0.99
479_I	505_L	1.192	0.99
127_V	156_L	1.188	0.99
305_R	317_L	1.188	0.99
18_A	21_K	1.187	0.99
227_E	230_R	1.184	0.99
220_D	223_V	1.183	0.99
505_L	537_T	1.180	0.99
169_I	243_L	1.177	0.99
236_E	240_K	1.175	0.99
12_K	16_K	1.173	0.99
63_R	85_I	1.172	0.99
63_R	86_A	1.171	0.99
244_E	248_K	1.169	0.99
200_D	203_R	1.158	0.99
254_R	402_L	1.156	0.99
535_K	539_I	1.155	0.99
13_E	17_A	1.152	0.99
14_E	17_A	1.151	0.99
274_K	278_A	1.151	0.99
70_V	83_L	1.150	0.99
64_Q	68_E	1.142	0.99
16_K	20_L	1.142	0.99
105_P	109_E	1.141	0.99
294_F	353_A	1.141	0.99
58_A	65_I	1.133	0.99
378_G	421_D	1.133	0.99
40_D	43_H	1.129	0.99
494_I	497_R	1.129	0.99
117_T	120_G	1.116	0.99
543_N	546_Q	1.111	0.99
129_F	153_C	1.099	0.99
39_K	43_H	1.099	0.99
185_V	201_G	1.096	0.99
241_Y	244_E	1.096	0.99
155_V	490_A	1.096	0.99
83_L	93_F	1.092	0.99
45_D	477_K	1.092	0.99
11_L	14_E	1.091	0.99
103_L	480_G	1.089	0.99
54_L	65_I	1.082	0.99
298_T	356_A	1.081	0.99
482_F	540_T	1.079	0.99
444_I	538_Q	1.079	0.99
463_D	466_H	1.072	0.99
24_L	58_A	1.071	0.99
113_A	158_K	1.067	0.99
129_F	165_R	1.063	0.99
115_G	543_N	1.057	0.99
437_A	502_I	1.056	0.99
252_N	394_R	1.055	0.99
334_K	493_R	1.054	0.99
342_D	373_H	1.052	0.98
300_G	303_K	1.049	0.98
345_G	349_R	1.045	0.98
150_D	406_R	1.043	0.98
14_E	18_A	1.043	0.98
334_K	367_E	1.039	0.98
474_D	508_A	1.039	0.98
205_E	209_A	1.038	0.98
276_L	280_R	1.038	0.98
126_Q	332_F	1.034	0.98
125_V	161_Y	1.032	0.98
273_D	308_I	1.026	0.98
471_K	516_E	1.025	0.98
448_L	535_K	1.024	0.98
365_E	493_R	1.019	0.98
212_K	215_A	1.018	0.98
512_F	518_V	1.016	0.98
231_L	235_R	1.015	0.98
299_F	356_A	1.013	0.98
19_V	24_L	1.011	0.98
202_Y	208_I	1.010	0.98
444_I	509_L	1.010	0.98
174_N	178_N	1.010	0.98
174_N	177_N	1.007	0.98
478_T	505_L	1.004	0.98
499_T	548_I	1.003	0.98
373_H	380_K	1.002	0.98
122_G	162_D	1.000	0.98
248_K	251_E	0.999	0.98
107_V	536_A	0.999	0.98
22_A	25_A	0.995	0.98
472_E	516_E	0.987	0.98
315_T	318_L	0.985	0.98
278_A	359_Y	0.984	0.98
188_F	191_L	0.982	0.98
472_E	533_L	0.974	0.97
164_S	332_F	0.968	0.97
207_I	211_G	0.967	0.97
108_L	536_A	0.966	0.97
242_E	246_L	0.952	0.97
119_I	487_A	0.950	0.97
69_I	91_I	0.949	0.97
309_K	314_Y	0.948	0.97
185_V	207_I	0.948	0.97
107_V	115_G	0.947	0.97
352_A	356_A	0.947	0.97
278_A	329_D	0.946	0.97
124_R	333_D	0.944	0.97
308_I	314_Y	0.944	0.97
245_K	248_K	0.936	0.97
186_R	207_I	0.935	0.97
218_Y	222_F	0.932	0.97
148_V	414_A	0.931	0.97
74_D	82_K	0.930	0.97
545_L	552_A	0.929	0.97
489_A	495_P	0.926	0.97
169_I	262_S	0.926	0.97
475_L	505_L	0.925	0.97
441_H	554_E	0.924	0.97
399_E	426_V	0.923	0.97
150_D	549_G	0.915	0.96
68_E	72_H	0.910	0.96
306_V	317_L	0.909	0.96
204_G	207_I	0.908	0.96
166_E	323_Y	0.906	0.96
125_V	156_L	0.905	0.96
399_E	422_L	0.903	0.96
503_Y	507_S	0.902	0.96
232_A	236_E	0.901	0.96
338_V	369_I	0.901	0.96
191_L	215_A	0.899	0.96
337_N	354_I	0.896	0.96
111_G	539_I	0.893	0.96
154_N	157_S	0.890	0.96
336_I	493_R	0.888	0.96
180_A	231_L	0.884	0.96
521_P	524_E	0.882	0.96
112_E	542_N	0.880	0.95
152_L	338_V	0.878	0.95
11_L	50_M	0.878	0.95
184_E	230_R	0.875	0.95
488_E	497_R	0.872	0.95
394_R	398_E	0.871	0.95
296_S	356_A	0.868	0.95
305_R	346_Y	0.868	0.95
451_G	519_I	0.862	0.95
371_L	385_K	0.862	0.95
145_G	409_F	0.856	0.95
107_V	114_Y	0.855	0.95
276_L	307_L	0.852	0.95
104_I	532_A	0.851	0.95
305_R	350_M	0.848	0.94
115_G	483_P	0.845	0.94
107_V	540_T	0.844	0.94
445_C	449_R	0.844	0.94
188_F	193_L	0.841	0.94
287_E	290_G	0.841	0.94
467_I	529_A	0.838	0.94
222_F	225_E	0.838	0.94
485_A	498_V	0.835	0.94
22_A	68_E	0.835	0.94
182_S	204_G	0.834	0.94
43_H	47_S	0.833	0.94
407_Y	437_A	0.833	0.94
75_K	80_I	0.831	0.94
37_T	481_G	0.827	0.94
153_C	157_S	0.827	0.94
247_R	260_W	0.827	0.94
437_A	499_T	0.826	0.94
146_A	255_V	0.825	0.94
176_I	239_L	0.825	0.94
321_I	353_A	0.824	0.94
103_L	106_S	0.822	0.93
22_A	58_A	0.821	0.93
127_V	163_V	0.820	0.93
189_E	192_G	0.819	0.93
97_N	470_E	0.818	0.93
204_G	211_G	0.817	0.93
274_K	325_K	0.816	0.93
423_D	426_V	0.816	0.93
351_K	360_E	0.815	0.93
195_K	198_P	0.814	0.93
154_N	165_R	0.814	0.93
440_A	541_L	0.813	0.93
280_R	283_G	0.813	0.93
61_A	67_E	0.813	0.93
408_F	425_A	0.812	0.93
275_A	322_A	0.812	0.93
373_H	419_D	0.812	0.93
214_L	217_E	0.812	0.93
323_Y	327_K	0.810	0.93
147_A	255_V	0.810	0.93
326_D	329_D	0.809	0.93
294_F	356_A	0.807	0.93
542_N	546_Q	0.807	0.93
73_F	83_L	0.807	0.93
380_K	419_D	0.807	0.93
76_G	79_S	0.806	0.93
204_G	210_I	0.806	0.93
80_I	93_F	0.803	0.93
328_L	359_Y	0.802	0.93
267_Y	326_D	0.802	0.93
445_C	542_N	0.801	0.93
373_H	382_K	0.801	0.93
501_Y	540_T	0.800	0.93
189_E	194_E	0.799	0.92
332_F	335_L	0.796	0.92
14_E	24_L	0.795	0.92
80_I	83_L	0.793	0.92
242_E	385_K	0.792	0.92
202_Y	206_D	0.791	0.92
143_A	409_F	0.791	0.92
66_A	85_I	0.789	0.92
138_L	242_E	0.789	0.92
202_Y	210_I	0.789	0.92
52_M	88_P	0.789	0.92
71_A	74_D	0.789	0.92
209_A	212_K	0.787	0.92
301_D	305_R	0.786	0.92
19_V	22_A	0.784	0.92
448_L	534_M	0.782	0.92
51_A	66_A	0.782	0.92
126_Q	339_W	0.782	0.92
202_Y	207_I	0.781	0.92
444_I	537_T	0.781	0.92
23_G	68_E	0.779	0.92
516_E	530_R	0.778	0.91
126_Q	164_S	0.778	0.91
50_M	54_L	0.778	0.91
429_S	435_Y	0.772	0.91
196_P	199_E	0.767	0.91
542_N	554_E	0.762	0.91
45_D	473_Y	0.761	0.91
139_H	374_L	0.761	0.91
56_R	59_K	0.759	0.90
488_E	491_E	0.759	0.90
18_A	72_H	0.759	0.90
340_G	344_H	0.756	0.90
305_R	353_A	0.755	0.90
463_D	529_A	0.755	0.90
467_I	530_R	0.754	0.90
114_Y	540_T	0.752	0.90
452_E	457_K	0.751	0.90
486_V	490_A	0.751	0.90
339_W	366_V	0.751	0.90
512_F	534_M	0.750	0.90
130_V	167_Y	0.749	0.90
151_S	547_L	0.749	0.90
205_E	208_I	0.749	0.90
317_L	350_M	0.748	0.90
48_T	51_A	0.747	0.90
248_K	394_R	0.747	0.90
279_L	357_L	0.747	0.90
103_L	107_V	0.746	0.90
104_I	476_L	0.745	0.90
536_A	539_I	0.745	0.90
297_T	302_D	0.744	0.90
483_P	487_A	0.741	0.89
51_A	69_I	0.741	0.89
521_P	527_S	0.741	0.89
324_H	361_K	0.741	0.89
152_L	369_I	0.739	0.89
201_G	204_G	0.734	0.89
360_E	366_V	0.732	0.89
79_S	96_N	0.730	0.89
344_H	348_P	0.730	0.89
428_T	435_Y	0.728	0.89
243_L	260_W	0.726	0.88
344_H	370_Q	0.726	0.88
17_A	20_L	0.726	0.88
114_Y	543_N	0.724	0.88
485_A	488_E	0.722	0.88
448_L	531_L	0.722	0.88
182_S	185_V	0.720	0.88
243_L	262_S	0.718	0.88
49_N	52_M	0.717	0.88
119_I	161_Y	0.716	0.88
145_G	369_I	0.714	0.88
485_A	497_R	0.713	0.88
161_Y	334_K	0.713	0.88
125_V	334_K	0.712	0.87
222_F	234_F	0.711	0.87
18_A	24_L	0.710	0.87
48_T	93_F	0.709	0.87
218_Y	237_Y	0.709	0.87
181_L	185_V	0.709	0.87
370_Q	415_D	0.709	0.87
74_D	83_L	0.708	0.87
339_W	350_M	0.707	0.87
157_S	256_P	0.705	0.87
454_Q	457_K	0.705	0.87
38_P	47_S	0.705	0.87
420_F	425_A	0.705	0.87
127_V	336_I	0.704	0.87
61_A	65_I	0.701	0.87
169_I	260_W	0.701	0.87
404_A	435_Y	0.701	0.87
275_A	357_L	0.700	0.87
509_L	513_Y	0.700	0.87
345_G	348_P	0.696	0.86
202_Y	205_E	0.696	0.86
204_G	214_L	0.696	0.86
317_L	353_A	0.695	0.86
41_K	44_G	0.693	0.86
202_Y	211_G	0.693	0.86
108_L	539_I	0.693	0.86
157_S	163_V	0.692	0.86
22_A	72_H	0.692	0.86
325_K	359_Y	0.691	0.86
371_L	417_H	0.688	0.86
176_I	385_K	0.687	0.86
34_V	53_Q	0.685	0.85
182_S	201_G	0.685	0.85
65_I	68_E	0.683	0.85
481_G	485_A	0.682	0.85
127_V	338_V	0.681	0.85
377_N	423_D	0.681	0.85
234_F	237_Y	0.681	0.85
217_E	237_Y	0.680	0.85
228_S	235_R	0.680	0.85
191_L	194_E	0.677	0.85
221_R	224_N	0.675	0.85
229_E	232_A	0.675	0.85
13_E	16_K	0.675	0.85
373_H	417_H	0.675	0.85
295_R	304_D	0.674	0.84
458_P	461_D	0.674	0.84
336_I	369_I	0.671	0.84
120_G	125_V	0.671	0.84
350_M	353_A	0.670	0.84
20_L	23_G	0.668	0.84
339_W	368_I	0.667	0.84
140_L	396_L	0.667	0.84
138_L	142_H	0.666	0.84
521_P	526_K	0.665	0.84
35_L	80_I	0.664	0.84
292_T	307_L	0.663	0.83
457_K	460_A	0.662	0.83
430_N	433_P	0.662	0.83
288_E	293_W	0.661	0.83
328_L	331_G	0.660	0.83
383_M	390_A	0.658	0.83
96_N	99_Y	0.657	0.83
197_M	201_G	0.656	0.83
340_G	382_K	0.656	0.83
340_G	373_H	0.654	0.83
181_L	218_Y	0.654	0.83
126_Q	259_V	0.654	0.83
13_E	21_K	0.652	0.82
314_Y	319_P	0.652	0.82
542_N	552_A	0.650	0.82
114_Y	539_I	0.650	0.82
392_T	395_D	0.649	0.82
136_G	343_H	0.648	0.82
72_H	75_K	0.647	0.82
253_F	397_I	0.646	0.82
106_S	109_E	0.644	0.82
182_S	186_R	0.641	0.81
324_H	328_L	0.641	0.81
214_L	218_Y	0.641	0.81
336_I	367_E	0.640	0.81
223_V	226_E	0.640	0.81
446_S	519_I	0.639	0.81
315_T	349_R	0.639	0.81
233_F	237_Y	0.639	0.81
407_Y	499_T	0.638	0.81
188_F	223_V	0.637	0.81
215_A	218_Y	0.636	0.81
355_E	360_E	0.634	0.81
157_S	162_D	0.634	0.81
442_A	445_C	0.633	0.81
401_G	405_V	0.633	0.81
396_L	407_Y	0.632	0.80
50_M	69_I	0.631	0.80
311_D	315_T	0.631	0.80
261_Y	267_Y	0.631	0.80
333_D	363_T	0.630	0.80
369_I	372_V	0.630	0.80
175_Q	386_R	0.629	0.80
15_I	93_F	0.628	0.80
222_F	226_E	0.628	0.80
127_V	165_R	0.628	0.80
439_Y	510_H	0.627	0.80
235_R	239_L	0.627	0.80
114_Y	483_P	0.624	0.80
78_A	96_N	0.623	0.80
151_S	410_A	0.622	0.79
447_M	509_L	0.622	0.79
52_M	63_R	0.620	0.79
317_L	349_R	0.620	0.79
437_A	541_L	0.619	0.79
466_H	525_E	0.618	0.79
18_A	23_G	0.618	0.79
116_E	486_V	0.617	0.79
434_V	550_V	0.617	0.79
337_N	350_M	0.616	0.79
67_E	85_I	0.615	0.79
41_K	477_K	0.614	0.79
55_A	62_P	0.614	0.79
299_F	352_A	0.613	0.78
174_N	385_K	0.613	0.78
159_A	487_A	0.613	0.78
459_A	462_L	0.611	0.78
269_N	272_I	0.610	0.78
321_I	354_I	0.610	0.78
242_E	309_K	0.610	0.78
117_T	487_A	0.610	0.78
421_D	424_L	0.609	0.78
466_H	529_A	0.608	0.78
33_V	50_M	0.607	0.78
47_S	94_Y	0.606	0.78
218_Y	221_R	0.605	0.78
216_E	219_G	0.604	0.77
339_W	370_Q	0.604	0.77
439_Y	513_Y	0.604	0.77
382_K	385_K	0.603	0.77
371_L	374_L	0.603	0.77
85_I	91_I	0.602	0.77
114_Y	536_A	0.602	0.77
374_L	383_M	0.601	0.77
378_G	381_M	0.601	0.77
353_A	366_V	0.600	0.77
337_N	353_A	0.599	0.77
218_Y	225_E	0.599	0.77
273_D	280_R	0.599	0.77
139_H	142_H	0.598	0.77
11_L	15_I	0.598	0.77
38_P	44_G	0.598	0.77
306_V	315_T	0.598	0.77
462_L	465_S	0.597	0.77
377_N	417_H	0.597	0.77
484_E	487_A	0.596	0.76
206_D	209_A	0.596	0.76
115_G	486_V	0.593	0.76
450_Q	519_I	0.593	0.76
187_Y	219_G	0.593	0.76
286_Y	293_W	0.592	0.76
121_N	491_E	0.592	0.76
413_S	416_T	0.591	0.76
475_L	512_F	0.591	0.76
123_E	161_Y	0.590	0.76
486_V	498_V	0.590	0.76
471_K	511_S	0.589	0.76
210_I	213_R	0.589	0.76
438_Q	553_P	0.589	0.76
276_L	283_G	0.588	0.75
296_S	299_F	0.587	0.75
12_K	20_L	0.587	0.75
177_N	181_L	0.586	0.75
205_E	212_K	0.586	0.75
280_R	284_H	0.586	0.75
214_L	222_F	0.585	0.75
50_M	53_Q	0.582	0.75
191_L	199_E	0.581	0.75
121_N	161_Y	0.581	0.75
209_A	387_T	0.581	0.75
44_G	86_A	0.581	0.75
354_I	359_Y	0.580	0.75
270_G	274_K	0.580	0.75
174_N	309_K	0.579	0.74
105_P	532_A	0.578	0.74
97_N	101_T	0.578	0.74
502_I	540_T	0.578	0.74
324_H	350_M	0.577	0.74
35_L	53_Q	0.576	0.74
14_E	19_V	0.575	0.74
351_K	361_K	0.574	0.74
215_A	219_G	0.573	0.74
384_S	387_T	0.573	0.74
408_F	411_M	0.572	0.74
213_R	241_Y	0.572	0.74
396_L	427_S	0.572	0.74
132_A	167_Y	0.571	0.73
291_A	306_V	0.571	0.73
107_V	539_I	0.570	0.73
243_L	247_R	0.570	0.73
275_A	321_I	0.569	0.73
99_Y	102_K	0.569	0.73
408_F	418_M	0.567	0.73
180_A	239_L	0.566	0.73
411_M	424_L	0.565	0.73
437_A	503_Y	0.565	0.73
25_A	29_Q	0.564	0.72
190_A	211_G	0.563	0.72
448_L	451_G	0.563	0.72
143_A	147_A	0.563	0.72
144_R	409_F	0.563	0.72
257_F	260_W	0.560	0.72
178_N	204_G	0.560	0.72
478_T	511_S	0.559	0.72
189_E	193_L	0.558	0.72
288_E	304_D	0.558	0.72
460_A	463_D	0.558	0.72
52_M	90_F	0.558	0.72
175_Q	385_K	0.557	0.72
115_G	539_I	0.556	0.71
190_A	212_K	0.556	0.71
288_E	295_R	0.555	0.71
213_R	217_E	0.555	0.71
461_D	528_R	0.555	0.71
279_L	284_H	0.555	0.71
59_K	65_I	0.554	0.71
492_K	497_R	0.554	0.71
517_K	527_S	0.554	0.71
81_E	94_Y	0.552	0.71
93_F	100_L	0.552	0.71
132_A	250_L	0.552	0.71
540_T	544_A	0.552	0.71
275_A	278_A	0.551	0.71
36_E	47_S	0.550	0.71
19_V	58_A	0.550	0.71
436_Y	440_A	0.549	0.70
15_I	20_L	0.548	0.70
339_W	346_Y	0.547	0.70
169_I	310_K	0.547	0.70
192_G	195_K	0.546	0.70
284_H	298_T	0.546	0.70
129_F	257_F	0.546	0.70
409_F	418_M	0.546	0.70
413_S	494_I	0.546	0.70
80_I	96_N	0.545	0.70
15_I	48_T	0.545	0.70
137_D	206_D	0.544	0.70
52_M	85_I	0.544	0.70
204_G	212_K	0.544	0.70
20_L	25_A	0.543	0.70
541_L	545_L	0.542	0.69
126_Q	166_E	0.542	0.69
243_L	259_V	0.541	0.69
522_E	526_K	0.541	0.69
166_E	259_V	0.541	0.69
297_T	300_G	0.541	0.69
181_L	221_R	0.540	0.69
143_A	393_M	0.539	0.69
78_A	102_K	0.538	0.69
182_S	207_I	0.538	0.69
109_E	461_D	0.538	0.69
185_V	211_G	0.536	0.69
370_Q	373_H	0.536	0.69
36_E	39_K	0.534	0.68
136_G	167_Y	0.534	0.68
284_H	294_F	0.533	0.68
16_K	30_I	0.533	0.68
15_I	50_M	0.533	0.68
38_P	43_H	0.533	0.68
450_Q	518_V	0.532	0.68
178_N	181_L	0.532	0.68
17_A	72_H	0.530	0.68
207_I	214_L	0.529	0.68
15_I	18_A	0.528	0.68
259_V	335_L	0.528	0.68
437_A	544_A	0.528	0.68
67_E	87_G	0.528	0.68
172_A	319_P	0.527	0.67
237_Y	241_Y	0.527	0.67
62_P	66_A	0.527	0.67
20_L	30_I	0.526	0.67
307_L	318_L	0.525	0.67
86_A	89_G	0.525	0.67
16_K	19_V	0.525	0.67
33_V	48_T	0.525	0.67
400_V	435_Y	0.525	0.67
177_N	180_A	0.523	0.67
341_A	344_H	0.523	0.67
40_D	94_Y	0.522	0.67
469_S	515_A	0.522	0.67
186_R	189_E	0.522	0.67
39_K	42_T	0.522	0.67
325_K	354_I	0.522	0.67
221_R	225_E	0.521	0.66
167_Y	374_L	0.521	0.66
187_Y	191_L	0.520	0.66
177_N	313_T	0.519	0.66
289_D	310_K	0.519	0.66
19_V	25_A	0.518	0.66
146_A	250_L	0.517	0.66
327_K	335_L	0.516	0.66
15_I	25_A	0.516	0.66
63_R	88_P	0.516	0.66
436_Y	510_H	0.516	0.66
201_G	207_I	0.515	0.66
374_L	378_G	0.515	0.66
18_A	68_E	0.515	0.66
178_N	201_G	0.514	0.65
190_A	215_A	0.514	0.65
167_Y	250_L	0.513	0.65
147_A	409_F	0.513	0.65
14_E	21_K	0.513	0.65
49_N	90_F	0.511	0.65
135_T	170_N	0.511	0.65
73_F	93_F	0.511	0.65
327_K	337_N	0.510	0.65
54_L	69_I	0.509	0.65
143_A	253_F	0.509	0.65
52_M	86_A	0.509	0.65
490_A	493_R	0.508	0.65
324_H	353_A	0.508	0.65
55_A	65_I	0.507	0.64
293_W	304_D	0.506	0.64
51_A	62_P	0.506	0.64
479_I	501_Y	0.505	0.64
204_G	208_I	0.505	0.64
440_A	506_A	0.504	0.64
189_E	197_M	0.504	0.64
396_L	425_A	0.503	0.64
14_E	22_A	0.503	0.64
270_G	273_D	0.502	0.64
254_R	401_G	0.502	0.64
168_Y	268_Q	0.501	0.64
308_I	315_T	0.501	0.64
495_P	499_T	0.501	0.64
176_I	262_S	0.500	0.63
151_S	499_T	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1f7uA	1	0.964	100	0.254	Contact Map
4r3zB	1	0.9694	100	0.255	Contact Map
4obyA	1	0.9478	100	0.259	Contact Map
4q2tA	1	0.9694	100	0.262	Contact Map
2zueA	1	0.9694	100	0.284	Contact Map
1iq0A	1	0.9209	100	0.301	Contact Map
3fnrA	1	0.8022	100	0.468	Contact Map
3tqoA	1	0.6331	100	0.715	Contact Map
3h99A	1	0.6655	100	0.726	Contact Map
3sp1A	1	0.5971	100	0.726	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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