NATB - BACSU - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

NATB - ABC transporter permease protein NatB

UniProt:	P46904	Sequences: MLSHIYKKEMIDALRDRKTILLTILVPMIMMLGLVFFYESMLSDKGEQYTLAVGHSLPPALESKLNEIDEISVKTFAKPEEAVDEGKADAYLNVPKEFDSYVNSMTPFKVDVYGNSIDQGSSNAMQLVQSALDQYKNEIVQQRLTNKHIDQSVIQPFTIQQKEADEEKGTSAIMLSAILPMLILTSIVSGAMPIALDIMAGEKDRKSIEALLLTPVSRNKVLVGKWLAVSTFGVASGVFALVFLILSTVLFTENLKTAFQLGDHMWSVIGASALIIVLSALLISAMELFISIMSSSVKEAQSYMSLVVFLPVFPMFFIFSKAPNQFDLSYFLIPFLNLHALFKQLLFGMVDPATILSTSGTIAVLIAIFFLLARACFLKDKWVLPK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	386 (358)
Sequences:	11045 (9192)
Seq/√Len:	485.8

ECOLI - YBHR YHHJ YBHS
BACSU - NATB YFIN YFIM YHAP YHGE
SULSO - Q97W41 Q7LY08

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
48_Q	88_A	5.701	1.00
79_P	91_Y	5.010	1.00
275_I	341_L	4.950	1.00
75_T	78_K	4.274	1.00
97_E	101_Y	4.238	1.00
82_A	88_A	3.690	1.00
5_I	224_G	3.573	1.00
101_Y	106_T	3.534	1.00
7_K	11_I	3.478	1.00
81_E	85_E	3.427	1.00
6_Y	231_T	3.416	1.00
76_F	80_E	3.212	1.00
6_Y	227_L	3.031	1.00
80_E	84_D	2.801	1.00
217_S	220_K	2.728	1.00
324_N	328_L	2.698	1.00
82_A	87_K	2.615	1.00
83_V	91_Y	2.429	1.00
238_V	273_A	2.371	1.00
9_E	225_K	2.367	1.00
281_L	366_I	2.335	1.00
78_K	82_A	2.331	1.00
356_L	360_G	2.327	1.00
49_Y	62_E	2.313	1.00
94_V	98_F	2.310	1.00
360_G	364_V	2.300	1.00
278_L	363_A	2.291	1.00
289_F	372_L	2.228	1.00
52_A	76_F	2.155	1.00
242_V	246_L	2.152	1.00
276_I	338_L	2.143	1.00
279_S	338_L	2.133	1.00
11_I	14_L	2.094	1.00
52_A	93_N	2.079	1.00
93_N	113_Y	2.043	1.00
76_F	93_N	1.971	1.00
282_L	366_I	1.908	1.00
285_A	366_I	1.881	1.00
351_D	354_T	1.877	1.00
271_A	345_L	1.852	1.00
330_Y	336_L	1.832	1.00
53_V	99_D	1.828	1.00
270_G	274_L	1.821	1.00
55_H	58_P	1.811	1.00
364_V	368_I	1.800	1.00
319_F	330_Y	1.785	1.00
50_T	79_P	1.766	1.00
230_S	277_V	1.763	1.00
340_A	358_T	1.700	1.00
11_I	15_R	1.700	1.00
51_L	58_P	1.699	1.00
230_S	281_L	1.698	1.00
237_G	276_I	1.659	1.00
88_A	91_Y	1.631	1.00
278_L	366_I	1.621	1.00
365_L	369_F	1.608	1.00
10_M	235_A	1.592	1.00
202_E	225_K	1.590	1.00
331_F	337_N	1.573	1.00
308_V	311_P	1.550	1.00
77_A	80_E	1.547	1.00
46_G	74_K	1.541	1.00
81_E	84_D	1.540	1.00
14_L	17_R	1.520	1.00
8_K	202_E	1.518	1.00
46_G	72_S	1.514	1.00
132_L	136_K	1.509	1.00
57_L	99_D	1.507	1.00
275_I	359_S	1.502	1.00
233_G	280_A	1.485	1.00
279_S	283_I	1.451	1.00
63_S	66_N	1.448	1.00
278_L	359_S	1.445	1.00
282_L	369_F	1.444	1.00
371_L	375_A	1.443	1.00
327_D	331_F	1.440	1.00
48_Q	82_A	1.436	1.00
234_V	277_V	1.435	1.00
331_F	336_L	1.425	1.00
357_S	361_T	1.412	1.00
289_F	373_A	1.395	1.00
324_N	327_D	1.392	1.00
312_V	316_F	1.387	1.00
136_K	140_V	1.381	1.00
55_H	99_D	1.376	1.00
56_S	59_P	1.367	1.00
292_I	376_C	1.360	1.00
80_E	113_Y	1.347	1.00
78_K	81_E	1.343	1.00
57_L	102_V	1.337	1.00
77_A	81_E	1.335	1.00
97_E	100_S	1.323	1.00
219_N	374_R	1.315	1.00
140_V	143_R	1.309	1.00
90_A	124_A	1.307	1.00
93_N	111_D	1.303	1.00
129_Q	133_D	1.298	1.00
145_T	148_H	1.297	1.00
219_N	223_V	1.292	1.00
325_Q	329_S	1.290	1.00
242_V	245_I	1.288	1.00
47_E	92_L	1.281	1.00
64_K	67_E	1.281	1.00
275_I	345_L	1.279	1.00
361_T	365_L	1.279	1.00
325_Q	328_L	1.279	1.00
125_M	129_Q	1.267	1.00
328_L	331_F	1.266	1.00
302_S	305_S	1.265	1.00
200_A	203_K	1.255	1.00
133_D	136_K	1.253	1.00
52_A	96_K	1.249	1.00
319_F	322_A	1.236	1.00
289_F	376_C	1.231	1.00
58_P	99_D	1.230	1.00
361_T	364_V	1.230	1.00
337_N	361_T	1.225	1.00
44_D	72_S	1.222	1.00
344_Q	348_G	1.220	1.00
282_L	365_L	1.205	1.00
6_Y	224_G	1.204	1.00
231_T	235_A	1.204	1.00
268_V	271_A	1.202	1.00
328_L	332_L	1.201	1.00
46_G	89_D	1.198	1.00
135_Y	139_I	1.196	1.00
220_K	224_G	1.192	1.00
241_L	276_I	1.191	1.00
282_L	362_I	1.189	1.00
280_A	284_S	1.187	1.00
51_L	54_G	1.186	1.00
336_L	340_A	1.177	1.00
296_S	299_E	1.171	1.00
243_F	247_S	1.170	1.00
127_L	132_L	1.162	1.00
254_N	268_V	1.160	1.00
333_I	336_L	1.160	1.00
10_M	231_T	1.152	1.00
211_L	221_V	1.148	1.00
359_S	363_A	1.148	1.00
138_E	141_Q	1.148	1.00
222_L	374_R	1.142	1.00
60_A	63_S	1.134	1.00
143_R	146_N	1.132	1.00
180_P	184_L	1.132	1.00
181_M	184_L	1.130	1.00
202_E	207_S	1.121	1.00
76_F	91_Y	1.117	1.00
51_L	62_E	1.113	1.00
183_I	191_A	1.111	1.00
344_Q	350_V	1.111	1.00
174_M	177_A	1.104	1.00
350_V	354_T	1.099	1.00
289_F	369_F	1.091	1.00
139_I	142_Q	1.086	1.00
127_L	131_A	1.085	1.00
31_M	244_L	1.083	1.00
53_V	97_E	1.082	1.00
110_V	113_Y	1.076	1.00
10_M	228_A	1.068	1.00
184_L	190_G	1.068	1.00
83_V	88_A	1.067	1.00
312_V	315_M	1.067	1.00
224_G	228_A	1.061	1.00
314_P	318_I	1.046	1.00
138_E	142_Q	1.045	1.00
294_S	299_E	1.041	1.00
51_L	55_H	1.040	1.00
178_I	182_L	1.037	1.00
148_H	151_Q	1.034	1.00
5_I	216_V	1.033	1.00
134_Q	137_N	1.031	1.00
142_Q	145_T	1.022	1.00
185_T	189_S	1.017	1.00
130_S	134_Q	1.014	1.00
92_L	112_V	1.013	1.00
286_M	307_V	1.001	1.00
64_K	138_E	0.998	1.00
6_Y	228_A	0.997	1.00
184_L	191_A	0.996	1.00
146_N	150_D	0.995	1.00
200_A	204_D	0.994	1.00
147_K	150_D	0.993	1.00
337_N	358_T	0.992	1.00
131_A	135_Y	0.989	1.00
155_Q	158_T	0.986	1.00
62_E	66_N	0.985	1.00
99_D	103_N	0.976	1.00
182_L	185_T	0.976	1.00
31_M	35_V	0.975	1.00
368_I	372_L	0.968	1.00
184_L	338_L	0.966	1.00
135_Y	138_E	0.965	1.00
272_S	342_F	0.963	1.00
32_L	243_F	0.962	1.00
179_L	182_L	0.956	1.00
174_M	178_I	0.956	1.00
196_L	300_A	0.953	1.00
294_S	303_Y	0.949	1.00
306_L	310_L	0.948	1.00
305_S	309_F	0.946	1.00
340_A	344_Q	0.934	1.00
269_I	273_A	0.934	1.00
115_N	118_D	0.927	1.00
270_G	273_A	0.924	1.00
287_E	291_S	0.923	1.00
322_A	327_D	0.920	1.00
199_M	202_E	0.920	1.00
128_V	131_A	0.918	1.00
271_A	274_L	0.911	1.00
10_M	14_L	0.906	1.00
330_Y	333_I	0.905	1.00
47_E	90_A	0.901	1.00
16_D	19_T	0.901	1.00
299_E	303_Y	0.890	1.00
338_L	341_L	0.885	1.00
307_V	310_L	0.884	1.00
119_Q	122_S	0.884	1.00
285_A	370_F	0.883	1.00
363_A	367_A	0.879	1.00
227_L	231_T	0.878	1.00
369_F	373_A	0.877	1.00
337_N	340_A	0.874	1.00
179_L	190_G	0.873	1.00
8_K	12_D	0.866	1.00
123_N	127_L	0.865	1.00
35_V	248_T	0.862	1.00
344_Q	354_T	0.858	1.00
309_F	312_V	0.856	1.00
91_Y	113_Y	0.851	1.00
137_N	141_Q	0.849	1.00
299_E	302_S	0.846	1.00
285_A	369_F	0.846	1.00
176_S	181_M	0.834	1.00
39_E	42_L	0.832	1.00
226_W	284_S	0.829	1.00
50_T	91_Y	0.828	1.00
251_F	254_N	0.827	1.00
323_P	327_D	0.827	1.00
180_P	190_G	0.826	1.00
120_G	123_N	0.823	1.00
323_P	326_F	0.823	1.00
307_V	311_P	0.820	1.00
353_A	357_S	0.819	1.00
180_P	183_I	0.818	1.00
289_F	293_M	0.816	1.00
59_P	63_S	0.815	1.00
66_N	73_V	0.813	1.00
366_I	369_F	0.810	1.00
28_M	32_L	0.809	1.00
58_P	62_E	0.806	1.00
207_S	210_A	0.805	1.00
158_T	161_Q	0.804	1.00
139_I	143_R	0.800	1.00
48_Q	91_Y	0.799	1.00
31_M	34_L	0.797	1.00
358_T	362_I	0.796	1.00
101_Y	108_F	0.795	1.00
344_Q	358_T	0.794	1.00
53_V	94_V	0.791	1.00
203_K	208_I	0.788	1.00
40_S	43_S	0.781	1.00
61_L	94_V	0.779	1.00
175_L	179_L	0.777	1.00
133_D	137_N	0.776	1.00
159_I	162_K	0.775	1.00
275_I	355_I	0.768	1.00
276_I	342_F	0.766	1.00
4_H	7_K	0.763	1.00
319_F	327_D	0.762	1.00
304_M	308_V	0.762	1.00
54_G	58_P	0.761	1.00
58_P	94_V	0.760	1.00
288_L	373_A	0.759	1.00
76_F	79_P	0.758	1.00
180_P	191_A	0.757	1.00
185_T	188_V	0.756	1.00
122_S	125_M	0.755	1.00
311_P	335_F	0.750	1.00
184_L	335_F	0.748	1.00
278_L	362_I	0.748	1.00
8_K	11_I	0.747	1.00
208_I	221_V	0.745	1.00
230_S	284_S	0.745	1.00
360_G	363_A	0.744	1.00
234_V	238_V	0.744	1.00
59_P	62_E	0.743	1.00
51_L	99_D	0.742	1.00
226_W	285_A	0.738	1.00
311_P	333_I	0.737	1.00
186_S	190_G	0.735	1.00
50_T	53_V	0.734	1.00
126_Q	129_Q	0.733	1.00
287_E	304_M	0.727	1.00
190_G	236_S	0.727	1.00
75_T	79_P	0.726	1.00
9_E	228_A	0.726	1.00
60_A	64_K	0.726	1.00
142_Q	146_N	0.725	1.00
79_P	82_A	0.724	1.00
226_W	281_L	0.722	1.00
201_G	205_R	0.721	1.00
56_S	60_A	0.720	1.00
140_V	144_L	0.719	1.00
136_K	139_I	0.719	1.00
357_S	360_G	0.719	1.00
32_L	36_F	0.718	1.00
137_N	140_V	0.717	1.00
188_V	192_M	0.717	1.00
181_M	186_S	0.713	1.00
143_R	147_K	0.712	1.00
33_G	36_F	0.712	1.00
289_F	292_I	0.707	1.00
204_D	297_V	0.706	1.00
176_S	180_P	0.705	1.00
341_L	345_L	0.705	1.00
177_A	191_A	0.704	1.00
320_S	324_N	0.703	1.00
201_G	204_D	0.701	1.00
161_Q	164_A	0.701	1.00
26_V	30_M	0.700	1.00
352_P	356_L	0.700	1.00
179_L	185_T	0.699	1.00
82_A	85_E	0.698	1.00
216_V	221_V	0.697	1.00
187_I	191_A	0.694	1.00
30_M	34_L	0.693	1.00
355_I	358_T	0.693	1.00
124_A	127_L	0.692	1.00
177_A	188_V	0.691	1.00
80_E	91_Y	0.690	1.00
367_A	371_L	0.689	1.00
180_P	187_I	0.685	1.00
302_S	306_L	0.684	1.00
65_L	128_V	0.682	1.00
236_S	240_A	0.682	1.00
200_A	300_A	0.682	1.00
74_K	88_A	0.681	1.00
122_S	127_L	0.680	1.00
370_F	374_R	0.680	1.00
283_I	287_E	0.678	1.00
127_L	136_K	0.678	1.00
86_G	115_N	0.678	1.00
177_A	185_T	0.676	1.00
350_V	355_I	0.676	1.00
21_L	25_L	0.674	1.00
164_A	167_E	0.673	1.00
114_G	118_D	0.673	1.00
189_S	192_M	0.672	1.00
317_F	339_H	0.669	1.00
51_L	94_V	0.668	1.00
202_E	206_K	0.668	1.00
286_M	369_F	0.667	1.00
181_M	192_M	0.666	1.00
144_L	148_H	0.662	1.00
198_I	225_K	0.662	1.00
90_A	112_V	0.660	1.00
131_A	136_K	0.659	1.00
53_V	58_P	0.659	1.00
146_N	149_I	0.659	1.00
176_S	188_V	0.658	1.00
188_V	191_A	0.658	1.00
36_F	247_S	0.655	1.00
366_I	370_F	0.653	1.00
114_G	121_S	0.652	1.00
95_P	109_K	0.652	1.00
192_M	196_L	0.646	1.00
181_M	190_G	0.645	1.00
197_D	200_A	0.642	1.00
165_D	168_K	0.642	1.00
313_F	317_F	0.642	1.00
177_A	180_P	0.641	1.00
100_S	104_S	0.640	1.00
76_F	113_Y	0.637	1.00
362_I	365_L	0.637	1.00
13_A	232_F	0.636	1.00
83_V	113_Y	0.634	1.00
176_S	184_L	0.634	1.00
177_A	190_G	0.634	1.00
175_L	178_I	0.633	1.00
271_A	355_I	0.633	1.00
174_M	192_M	0.632	1.00
215_P	218_R	0.631	1.00
249_V	252_T	0.630	1.00
206_K	209_E	0.630	1.00
271_A	275_I	0.628	1.00
372_L	375_A	0.627	1.00
292_I	373_A	0.626	1.00
285_A	373_A	0.623	1.00
166_E	169_G	0.622	1.00
312_V	318_I	0.618	0.99
138_E	144_L	0.617	0.99
5_I	221_V	0.616	0.99
23_T	26_V	0.616	0.99
174_M	181_M	0.616	0.99
121_S	125_M	0.615	0.99
175_L	190_G	0.614	0.99
108_F	112_V	0.612	0.99
70_E	74_K	0.612	0.99
211_L	225_K	0.611	0.99
337_N	365_L	0.609	0.99
184_L	187_I	0.606	0.99
178_I	189_S	0.606	0.99
188_V	283_I	0.605	0.99
332_L	365_L	0.604	0.99
111_D	114_G	0.603	0.99
61_L	98_F	0.602	0.99
92_L	110_V	0.601	0.99
58_P	61_L	0.601	0.99
284_S	288_L	0.600	0.99
129_Q	132_L	0.599	0.99
290_I	303_Y	0.599	0.99
191_A	287_E	0.598	0.99
338_L	346_L	0.597	0.99
134_Q	138_E	0.595	0.99
241_L	272_S	0.595	0.99
153_V	156_P	0.594	0.99
145_T	151_Q	0.594	0.99
198_I	201_G	0.594	0.99
299_E	306_L	0.592	0.99
176_S	179_L	0.592	0.99
6_Y	10_M	0.591	0.99
141_Q	145_T	0.588	0.99
61_L	135_Y	0.588	0.99
50_T	75_T	0.587	0.99
71_I	74_K	0.586	0.99
372_L	376_C	0.584	0.99
304_M	317_F	0.583	0.99
13_A	228_A	0.581	0.99
273_A	276_I	0.580	0.99
98_F	135_Y	0.579	0.99
341_L	346_L	0.576	0.99
176_S	183_I	0.575	0.99
9_E	13_A	0.575	0.99
176_S	190_G	0.574	0.99
222_L	370_F	0.573	0.99
184_L	188_V	0.572	0.99
27_P	300_A	0.572	0.99
306_L	311_P	0.569	0.99
114_G	125_M	0.569	0.99
30_M	189_S	0.569	0.99
322_A	325_Q	0.567	0.99
238_V	269_I	0.567	0.99
9_E	221_V	0.566	0.99
375_A	378_L	0.566	0.99
182_L	188_V	0.565	0.99
101_Y	109_K	0.565	0.99
271_A	359_S	0.565	0.99
174_M	186_S	0.564	0.99
126_Q	130_S	0.564	0.99
22_L	26_V	0.564	0.99
4_H	8_K	0.563	0.99
186_S	191_A	0.563	0.99
128_V	132_L	0.563	0.99
182_L	186_S	0.561	0.99
125_M	128_V	0.560	0.99
313_F	316_F	0.559	0.99
210_A	214_T	0.558	0.99
356_L	359_S	0.557	0.99
5_I	9_E	0.557	0.99
89_D	115_N	0.557	0.99
300_A	304_M	0.557	0.99
355_I	359_S	0.556	0.99
130_S	133_D	0.556	0.99
113_Y	116_S	0.556	0.99
353_A	356_L	0.555	0.99
194_I	197_D	0.554	0.99
354_T	357_S	0.552	0.99
341_L	344_Q	0.551	0.99
83_V	86_G	0.550	0.99
352_P	355_I	0.548	0.99
358_T	361_T	0.548	0.99
181_M	189_S	0.547	0.99
61_L	132_L	0.547	0.99
341_L	362_I	0.546	0.99
290_I	304_M	0.546	0.99
105_M	108_F	0.546	0.99
285_A	292_I	0.545	0.99
60_A	142_Q	0.544	0.99
156_P	159_I	0.541	0.99
187_I	190_G	0.539	0.99
241_L	269_I	0.539	0.99
334_P	341_L	0.538	0.99
241_L	245_I	0.538	0.99
76_F	111_D	0.538	0.99
222_L	373_A	0.538	0.99
13_A	23_T	0.537	0.99
31_M	240_A	0.537	0.99
157_F	161_Q	0.536	0.99
54_G	59_P	0.534	0.99
182_L	190_G	0.533	0.98
49_Y	73_V	0.533	0.98
17_R	20_I	0.533	0.98
155_Q	159_I	0.532	0.98
363_A	366_I	0.531	0.98
224_G	227_L	0.530	0.98
115_N	121_S	0.527	0.98
177_A	187_I	0.527	0.98
341_L	355_I	0.522	0.98
179_L	191_A	0.522	0.98
183_I	189_S	0.521	0.98
342_F	346_L	0.521	0.98
202_E	221_V	0.521	0.98
341_L	359_S	0.520	0.98
57_L	135_Y	0.520	0.98
216_V	220_K	0.519	0.98
179_L	183_I	0.519	0.98
369_F	372_L	0.519	0.98
321_K	324_N	0.519	0.98
203_K	207_S	0.518	0.98
39_E	43_S	0.517	0.98
163_E	166_E	0.516	0.98
178_I	183_I	0.515	0.98
185_T	190_G	0.514	0.98
305_S	312_V	0.513	0.98
132_L	143_R	0.513	0.98
142_Q	147_K	0.513	0.98
110_V	115_N	0.512	0.98
335_F	339_H	0.512	0.98
226_W	230_S	0.511	0.98
361_T	368_I	0.511	0.98
114_G	117_I	0.510	0.98
235_A	238_V	0.509	0.98
288_L	291_S	0.509	0.98
290_I	294_S	0.509	0.98
277_V	281_L	0.509	0.98
9_E	198_I	0.507	0.98
120_G	128_V	0.507	0.98
180_P	185_T	0.506	0.98
301_Q	306_L	0.506	0.98
47_E	73_V	0.504	0.98
141_Q	146_N	0.504	0.98
252_T	269_I	0.502	0.98
337_N	341_L	0.502	0.98
94_V	110_V	0.501	0.98
108_F	115_N	0.500	0.98
147_K	151_Q	0.500	0.98

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3cniA	2	0.3549	99.6	0.721	Contact Map
2p0sA	2	0.3187	97.8	0.853	Contact Map
4tllA	1	0.4275	13.7	0.952	Contact Map
3cnbA	1	0.2927	7.6	0.957	Contact Map
3cg4A	1	0.2979	7.4	0.957	Contact Map
2wswA	3	0.4378	7.2	0.957	Contact Map
2qvgA	1	0.2876	6.5	0.959	Contact Map
3hdvA	3	0.2979	5.9	0.959	Contact Map
1dz3A	2	0.272	5.7	0.959	Contact Map
3hdgA	2	0.3005	5.5	0.96	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0113 seconds.