GREMLIN Database
RXL7 - Ribosome-associated protein L7Ae-like
UniProt: P46350 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 82 (78)
Sequences: 343 (289)
Seq/√Len: 32.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
23_L49_A3.5301.00
31_V49_A3.3731.00
35_K58_M3.2471.00
28_V79_A3.0051.00
33_V46_V2.7881.00
24_K52_Q2.2040.99
4_D21_K2.0150.98
31_V45_V1.8040.96
23_L54_I1.7870.96
43_S47_S1.7140.94
24_K49_A1.6650.94
44_S72_E1.6350.93
30_E57_S1.6090.92
19_T45_V1.5900.92
41_L63_K1.5820.92
60_E64_K1.5630.91
16_T45_V1.4900.89
23_L31_V1.4630.88
28_V31_V1.3610.84
45_V49_A1.3370.83
37_A62_M1.3000.81
47_S50_E1.2690.80
5_K78_V1.2290.77
16_T41_L1.2240.77
31_V56_V1.2100.76
21_K70_G1.2030.76
32_V61_S1.1590.73
35_K51_D1.1570.73
21_K25_R1.1550.73
32_V78_V1.1360.71
31_V40_I1.1300.71
6_V32_V1.0920.68
6_V78_V1.0840.68
38_D41_L1.0770.67
6_V9_A1.0630.66
23_L45_V1.0510.65
24_K51_D1.0470.65
7_S32_V1.0450.65
33_V38_D1.0290.64
24_K77_A1.0280.64
26_G52_Q1.0240.63
19_T79_A1.0180.63
11_S80_I1.0050.62
20_V45_V0.9990.61
45_V77_A0.9900.61
30_E55_S0.9630.59
6_V61_S0.9420.57
22_A81_I0.9410.57
76_A79_A0.8760.51
10_K39_P0.8620.50
28_V49_A0.8500.49
69_C78_V0.8330.48
18_Q74_G0.8280.47
5_K30_E0.8210.47
43_S53_G0.8200.47
37_A42_T0.8190.47
28_V44_S0.8150.46
46_V58_M0.8030.45
29_K57_S0.7790.43
33_V58_M0.7790.43
26_G55_S0.7700.43
9_A76_A0.7660.42
43_S54_I0.7630.42
40_I62_M0.7470.41
8_Q54_I0.7410.40
59_V77_A0.7360.40
26_G30_E0.7240.39
20_V80_I0.7230.39
54_I63_K0.7220.39
26_G48_L0.7220.39
23_L28_V0.7130.38
4_D77_A0.7130.38
6_V12_I0.7060.38
7_S47_S0.7030.37
53_G70_G0.7010.37
13_I41_L0.6990.37
16_T69_C0.6910.36
16_T79_A0.6870.36
8_Q77_A0.6870.36
17_K58_M0.6750.35
7_S70_G0.6740.35
14_I48_L0.6610.34
10_K48_L0.6600.34
44_S49_A0.6590.34
8_Q78_V0.6560.34
62_M71_I0.6510.33
13_I19_T0.6500.33
19_T77_A0.6500.33
33_V77_A0.6450.33
25_R57_S0.6320.32
36_D39_P0.6230.31
42_T56_V0.6110.30
18_Q65_L0.6000.30
35_K64_K0.5900.29
38_D47_S0.5890.29
47_S51_D0.5820.28
40_I80_I0.5800.28
38_D62_M0.5780.28
47_S53_G0.5720.28
59_V68_A0.5570.27
54_I77_A0.5540.27
23_L72_E0.5500.26
61_S64_K0.5500.26
5_K8_Q0.5490.26
27_S39_P0.5460.26
7_S10_K0.5410.26
64_K81_I0.5400.26
54_I68_A0.5380.26
37_A72_E0.5280.25
26_G74_G0.5230.25
22_A79_A0.5230.25
11_S40_I0.5110.24
20_V27_S0.5090.24
12_I42_T0.5060.24
47_S55_S0.5030.23
36_D61_S0.5030.23
54_I72_E0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cg6A 3 0.9634 99.6 0.494 Contact Map
3v7eA 1 0.9878 99.6 0.501 Contact Map
3ffmA 2 0.9146 99.6 0.511 Contact Map
1xbiA 1 1 99.6 0.52 Contact Map
3j61c 1 1 99.6 0.523 Contact Map
3zf7g 1 1 99.6 0.525 Contact Map
2jnbA 1 1 99.5 0.527 Contact Map
4a18G 1 1 99.5 0.528 Contact Map
3u5ec 1 1 99.5 0.529 Contact Map
1vx76 1 1 99.5 0.529 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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