GREMLIN Database
YQGH - Probable ABC transporter permease protein YqgH
UniProt: P46339 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 309 (255)
Sequences: 70264 (46245)
Seq/√Len: 2896.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
208_Q212_K4.0841.00
90_F94_A3.2211.00
200_Y209_T3.0241.00
185_A189_A2.9981.00
87_P90_F2.6251.00
88_F264_I2.6071.00
205_T208_Q2.5731.00
116_E196_R2.5561.00
54_G76_P2.5521.00
196_R214_L2.4881.00
199_S209_T2.4651.00
98_L169_T2.4071.00
187_A221_T2.3981.00
86_L90_F2.3521.00
102_I173_S2.3451.00
259_G267_L2.3291.00
100_A226_V2.2721.00
206_R209_T2.2501.00
207_W211_R2.2491.00
184_S222_L2.2451.00
119_P122_G2.2041.00
77_T81_P2.1671.00
108_I210_I2.0401.00
204_A208_Q2.0191.00
208_Q211_R1.9881.00
188_M218_A1.9691.00
180_I225_A1.9641.00
115_T189_A1.9451.00
195_L217_A1.9421.00
48_I52_V1.9081.00
94_A165_L1.8431.00
199_S204_A1.8321.00
68_F71_S1.8061.00
52_V56_Q1.8041.00
108_I218_A1.7701.00
87_P91_G1.7621.00
200_Y206_R1.7121.00
127_Q185_A1.7071.00
104_A226_V1.7031.00
107_G180_I1.7001.00
72_L77_T1.6981.00
196_R209_T1.6851.00
96_T230_M1.6781.00
94_A98_L1.6511.00
278_E281_T1.6481.00
99_S233_A1.6431.00
108_I184_S1.6001.00
114_M181_T1.5951.00
110_G181_T1.5851.00
119_P123_K1.5821.00
196_R200_Y1.5621.00
298_L302_Y1.5571.00
165_L258_A1.5271.00
69_L72_L1.4941.00
78_D281_T1.4891.00
33_T37_L1.4601.00
51_G287_L1.4501.00
193_K196_R1.4261.00
224_T228_L1.3981.00
122_G125_V1.3861.00
264_I268_N1.3851.00
72_L78_D1.3831.00
237_A241_Q1.3751.00
111_A184_S1.3681.00
180_I229_G1.3621.00
45_A49_F1.3601.00
215_V222_L1.3451.00
188_M214_L1.3431.00
84_G87_P1.3431.00
115_T185_A1.3401.00
95_V260_T1.3401.00
78_D81_P1.3251.00
246_N257_T1.3151.00
49_F53_K1.3151.00
184_S225_A1.2941.00
103_A229_G1.2911.00
239_A243_V1.2721.00
105_P109_A1.2691.00
116_E193_K1.2641.00
237_A266_T1.2561.00
193_K197_E1.2431.00
244_I258_A1.2411.00
199_S213_V1.2341.00
118_A123_K1.2311.00
92_S261_L1.2291.00
171_V243_V1.2261.00
65_P68_F1.2171.00
194_S197_E1.2171.00
164_S258_A1.2071.00
37_L41_A1.2041.00
108_I222_L1.1911.00
112_I188_M1.1911.00
98_L101_L1.1731.00
260_T263_T1.1681.00
26_V30_M1.1641.00
67_E70_T1.1561.00
268_N278_E1.1481.00
205_T209_T1.1451.00
57_S60_V1.1431.00
63_V66_I1.1411.00
259_G264_I1.1391.00
91_G94_A1.1291.00
101_L105_P1.1281.00
50_L287_L1.1151.00
125_V128_P1.1121.00
161_T166_L1.1071.00
28_G32_V1.1071.00
149_L167_A1.1021.00
168_G240_V1.1001.00
191_L217_A1.0891.00
66_I70_T1.0841.00
268_N272_T1.0791.00
184_S221_T1.0781.00
104_A222_L1.0781.00
65_P70_T1.0771.00
177_L181_T1.0771.00
27_R31_I1.0731.00
163_H166_L1.0651.00
196_R206_R1.0631.00
219_F223_M1.0611.00
78_D82_K1.0611.00
27_R30_M1.0611.00
30_M34_A1.0451.00
217_A220_P1.0371.00
267_L271_H1.0321.00
125_V129_V1.0311.00
63_V70_T1.0251.00
183_I225_A1.0231.00
112_I206_R1.0141.00
49_F52_V1.0121.00
259_G263_T1.0121.00
99_S103_A1.0051.00
93_F97_I1.0051.00
147_T151_P1.0031.00
102_I169_T1.0031.00
25_E28_G0.9941.00
160_G163_H0.9941.00
115_T188_M0.9881.00
98_L102_I0.9861.00
53_K283_W0.9751.00
161_T164_S0.9661.00
109_A113_F0.9651.00
99_S172_L0.9651.00
165_L169_T0.9641.00
112_I210_I0.9641.00
30_M33_T0.9611.00
300_I303_L0.9581.00
166_L170_I0.9561.00
89_I261_L0.9541.00
240_V260_T0.9541.00
236_E239_A0.9401.00
264_I285_M0.9351.00
123_K189_A0.9331.00
68_F72_L0.9291.00
76_P287_L0.9261.00
67_E71_S0.9251.00
236_E240_V0.9241.00
162_G166_L0.9181.00
204_A209_T0.9131.00
145_G243_V0.9091.00
172_L233_A0.9091.00
187_A218_A0.9081.00
264_I267_L0.9061.00
64_S67_E0.9001.00
209_T212_K0.8981.00
246_N258_A0.8951.00
266_T270_G0.8901.00
80_D86_L0.8891.00
269_M282_L0.8881.00
97_I101_L0.8871.00
121_W124_K0.8841.00
56_Q60_V0.8841.00
102_I105_P0.8751.00
111_A115_T0.8711.00
107_G181_T0.8681.00
75_N280_N0.8611.00
219_F222_L0.8571.00
29_R33_T0.8511.00
40_I44_V0.8511.00
101_L226_V0.8491.00
95_V165_L0.8471.00
210_I215_V0.8471.00
94_A97_I0.8431.00
42_A46_I0.8401.00
99_S169_T0.8401.00
241_Q263_T0.8381.00
169_T173_S0.8361.00
32_V36_A0.8351.00
89_I93_F0.8351.00
131_E182_S0.8311.00
85_V285_M0.8291.00
124_K127_Q0.8251.00
184_S218_A0.8231.00
111_A188_M0.8221.00
211_R215_V0.8201.00
218_A221_T0.8161.00
229_G233_A0.8151.00
180_I184_S0.8141.00
91_G165_L0.8111.00
103_A107_G0.8111.00
94_A166_L0.8101.00
145_G171_V0.8061.00
299_L302_Y0.8061.00
64_S70_T0.8061.00
25_E29_R0.8031.00
162_G165_L0.8001.00
65_P71_S0.7991.00
146_L150_V0.7971.00
103_A176_I0.7961.00
78_D278_E0.7921.00
113_F119_P0.7791.00
50_L283_W0.7751.00
163_H246_N0.7751.00
166_L169_T0.7751.00
209_T214_L0.7741.00
171_V239_A0.7741.00
90_F93_F0.7671.00
268_N285_M0.7591.00
293_S297_I0.7561.00
103_A180_I0.7541.00
95_V172_L0.7531.00
281_T285_M0.7531.00
150_V162_G0.7491.00
268_N281_T0.7481.00
114_M127_Q0.7481.00
206_R210_I0.7441.00
279_N282_L0.7421.00
53_K56_Q0.7421.00
142_G238_L0.7401.00
142_G242_M0.7341.00
96_T100_A0.7331.00
50_L286_G0.7291.00
191_L218_A0.7281.00
67_E72_L0.7281.00
138_S175_M0.7251.00
82_K86_L0.7241.00
195_L213_V0.7241.00
31_I34_A0.7231.00
111_A181_T0.7201.00
210_I214_L0.7201.00
79_S288_V0.7191.00
76_P80_D0.7141.00
45_A48_I0.7111.00
98_L173_S0.7101.00
164_S167_A0.7101.00
71_S77_T0.7081.00
104_A184_S0.7071.00
88_F261_L0.7061.00
88_F91_G0.7051.00
34_A37_L0.7001.00
95_V168_G0.6951.00
114_M126_L0.6921.00
131_E134_V0.6901.00
163_H167_A0.6871.00
184_S188_M0.6831.00
198_G202_L0.6821.00
193_K200_Y0.6821.00
283_W287_L0.6811.00
167_A171_V0.6791.00
244_I259_G0.6751.00
222_L225_A0.6711.00
76_P79_S0.6701.00
204_A212_K0.6691.00
221_T225_A0.6681.00
114_M185_A0.6651.00
265_I285_M0.6641.00
31_I35_C0.6631.00
236_E260_T0.6601.00
107_G184_S0.6581.00
100_A104_A0.6521.00
103_A233_A0.6521.00
280_N283_W0.6491.00
299_L303_L0.6491.00
119_P126_L0.6471.00
289_L293_S0.6471.00
295_L299_L0.6471.00
147_T150_V0.6461.00
92_S262_T0.6441.00
138_S238_L0.6431.00
214_L217_A0.6431.00
86_L89_I0.6421.00
273_T278_E0.6411.00
66_I71_S0.6401.00
95_V169_T0.6391.00
54_G284_S0.6391.00
134_V178_P0.6381.00
279_N283_W0.6371.00
141_Y174_V0.6321.00
222_L226_V0.6321.00
263_T267_L0.6311.00
100_A230_M0.6301.00
110_G177_L0.6291.00
168_G172_L0.6281.00
80_D83_Y0.6261.00
145_G148_V0.6231.00
298_L301_R0.6221.00
64_S68_F0.6201.00
262_T289_L0.6191.00
106_L173_S0.6191.00
79_S281_T0.6191.00
57_S67_E0.6181.00
24_D28_G0.6161.00
283_W286_G0.6161.00
40_I43_S0.6151.00
92_S234_F0.6151.00
240_V263_T0.6121.00
83_Y87_P0.6111.00
77_T80_D0.6051.00
294_F298_L0.6041.00
183_I221_T0.6041.00
261_L289_L0.6021.00
26_V29_R0.5971.00
39_M43_S0.5971.00
76_P284_S0.5941.00
110_G130_I0.5921.00
167_A243_V0.5921.00
54_G287_L0.5901.00
113_F117_I0.5871.00
96_T233_A0.5851.00
168_G244_I0.5841.00
122_G126_L0.5831.00
63_V67_E0.5791.00
24_D27_R0.5751.00
160_G164_S0.5721.00
46_I58_F0.5721.00
198_G201_A0.5711.00
238_L242_M0.5691.00
103_A173_S0.5671.00
75_N78_D0.5651.00
161_T170_I0.5651.00
127_Q182_S0.5641.00
172_L240_V0.5601.00
231_A235_G0.5571.00
76_P81_P0.5561.00
70_T75_N0.5561.00
36_A40_I0.5541.00
95_V99_S0.5521.00
72_L75_N0.5501.00
205_T211_R0.5481.00
263_T266_T0.5471.00
63_V69_L0.5471.00
146_L162_G0.5461.00
130_I178_P0.5451.00
121_W125_V0.5441.00
226_V229_G0.5431.00
84_G264_I0.5421.00
66_I69_L0.5411.00
129_V133_L0.5401.00
29_R32_V0.5401.00
209_T213_V0.5391.00
134_V179_T0.5381.00
176_I229_G0.5381.00
83_Y86_L0.5381.00
106_L177_L0.5351.00
118_A124_K0.5311.00
211_R214_L0.5291.00
176_I232_R0.5281.00
238_L241_Q0.5271.00
292_M295_L0.5271.00
172_L236_E0.5261.00
223_M226_V0.5261.00
44_V48_I0.5261.00
51_G55_L0.5251.00
104_A109_A0.5251.00
111_A185_A0.5251.00
112_I214_L0.5231.00
117_I123_K0.5231.00
139_V242_M0.5221.00
118_A193_K0.5201.00
191_L196_R0.5161.00
53_K57_S0.5151.00
232_R235_G0.5151.00
265_I286_G0.5121.00
63_V68_F0.5101.00
100_A233_A0.5091.00
110_G113_F0.5071.00
118_A121_W0.5071.00
56_Q66_I0.5061.00
272_T278_E0.5061.00
64_S69_L0.5011.00
197_E200_Y0.5011.00
52_V55_L0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2onkC 2 0.8091 100 0.324 Contact Map
3d31C 2 0.7896 100 0.341 Contact Map
4tquM 1 0.8738 100 0.35 Contact Map
3rlfG 1 0.8608 100 0.376 Contact Map
4tquN 1 0.8641 100 0.385 Contact Map
3rlfF 1 0.9385 100 0.393 Contact Map
4ymuD 2 0.6926 100 0.494 Contact Map
3tuiA 2 0.6796 99.9 0.515 Contact Map
2m8rA 1 0.1683 14.9 0.946 Contact Map
2kogA 1 0.1715 14.2 0.947 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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