LICR - BACSU - GREMLIN Contacts

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LICR - Probable licABCH operon regulator

UniProt:	P46321	Sequences: MLHGRLRDILRLLMAAEAPVTSSFFAAQLNVTTRTVRNDIKELQGVLSGHGAFVQSVRGSGYKLRIDDEQVFRTLLQDEFQQKKGLPVLPEERMAYLMKRLLLADHYLKLDELAEELFISKSTLQTDLKEVKKRLLPYRIVMETRPNYGFKLRGDEVQMRYCMAEYIVDERETEIDVLNEKADILPKEEIEIIRSAILKKMKNDRIPLSNMGLNNLIIHIAIACKRIRTENYVSLFPKDMDHILHQKEYQAAEAIVKELESKLSVTFPKDETAYITMHLLGTKRMTQSQCGEDTFSIEEETDQLTLAMIKAVDRELKLGILHDKELKIGLALHMKPAISRNRYGMNLRNPMLAAIKEHYPLAFEAGIIAGIVIKEQTGIEIHENEIGYLALHFGAAIERKKTESPPKRCIIVCASGAGSAQLLREKLRSHFGKRLDILGTAEYYSLDQMSYESIDFVISTIPIKKELPVPVLKVNTILGGTDFTKIESILSDEKEKANRYLKKELVFFQEDLRSKEEVIQFLGQKVVECGFADEEIIDSIFEREDMSPTCFGNLVAIPHPLVPQTKTTFWAVCTLKKPIDWESQRVQFVCLLCVEKENKADLQSMYKLLGSILDDPAAMNQLIKCRSYQELSDVFDQKMLS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	641 (620)
Sequences:	2288 (1993)
Seq/√Len:	80.0

ECOLI - FRVR
BACSU - LICR MANR MTLR

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
5_R	39_D	5.608	1.00
156_E	226_R	4.752	1.00
408_R	436_D	4.476	1.00
93_R	127_D	4.338	1.00
31_V	36_V	3.883	1.00
356_K	383_E	3.828	1.00
323_D	399_R	3.749	1.00
203_N	254_A	3.554	1.00
140_I	154_G	3.513	1.00
352_L	387_G	3.498	1.00
40_I	44_Q	3.487	1.00
100_R	116_E	3.465	1.00
119_I	124_L	3.428	1.00
627_S	630_E	3.291	1.00
511_D	576_K	3.197	1.00
139_R	158_Q	3.169	1.00
156_E	160_R	3.128	1.00
119_I	127_D	3.105	1.00
575_L	578_P	2.910	1.00
410_I	441_A	2.846	1.00
520_Q	537_I	2.714	1.00
313_D	319_G	2.712	1.00
374_K	380_E	2.710	1.00
587_Q	623_I	2.687	1.00
138_Y	165_E	2.667	1.00
413_C	416_G	2.657	1.00
160_R	271_E	2.637	1.00
424_R	428_R	2.612	1.00
523_G	537_I	2.609	1.00
516_E	544_E	2.586	1.00
503_K	629_Q	2.568	1.00
160_R	226_R	2.512	1.00
132_K	144_T	2.476	1.00
140_I	152_L	2.454	1.00
12_L	20_V	2.373	1.00
119_I	123_T	2.367	1.00
306_L	327_K	2.357	1.00
35_T	39_D	2.320	1.00
504_E	529_C	2.319	1.00
462_P	473_K	2.303	1.00
506_V	628_Y	2.250	1.00
323_D	396_A	2.190	1.00
514_S	517_E	2.169	1.00
12_L	25_F	2.160	1.00
155_D	158_Q	2.148	1.00
411_I	427_L	2.145	1.00
565_T	593_C	2.128	1.00
512_L	521_F	2.106	1.00
409_C	435_L	2.088	1.00
423_L	460_T	2.087	1.00
44_Q	56_S	2.080	1.00
55_Q	65_R	2.069	1.00
31_V	39_D	2.044	1.00
518_V	573_C	2.038	1.00
519_I	537_I	2.038	1.00
86_L	92_E	2.008	1.00
260_E	266_T	1.995	1.00
522_L	573_C	1.976	1.00
409_C	458_I	1.974	1.00
421_Q	424_R	1.940	1.00
527_V	532_A	1.938	1.00
522_L	591_L	1.937	1.00
356_K	363_F	1.935	1.00
219_H	278_H	1.935	1.00
244_L	269_K	1.899	1.00
143_E	153_R	1.894	1.00
524_Q	528_E	1.887	1.00
25_F	36_V	1.883	1.00
366_G	390_A	1.869	1.00
350_P	384_N	1.866	1.00
5_R	35_T	1.864	1.00
320_I	393_F	1.863	1.00
518_V	589_V	1.856	1.00
315_E	368_I	1.854	1.00
533_D	566_K	1.842	1.00
367_I	383_E	1.832	1.00
578_P	587_Q	1.830	1.00
543_R	549_T	1.830	1.00
540_I	591_L	1.823	1.00
94_M	131_V	1.819	1.00
475_N	482_D	1.811	1.00
413_C	420_A	1.806	1.00
305_T	334_M	1.805	1.00
370_G	389_L	1.805	1.00
44_Q	54_V	1.796	1.00
511_D	577_K	1.781	1.00
98_M	131_V	1.761	1.00
349_N	387_G	1.760	1.00
312_V	365_A	1.730	1.00
311_A	372_V	1.728	1.00
538_D	542_E	1.727	1.00
12_L	28_Q	1.722	1.00
531_F	567_T	1.711	1.00
509_Q	574_T	1.710	1.00
199_K	258_E	1.703	1.00
19_P	63_K	1.702	1.00
362_A	390_A	1.698	1.00
33_T	37_R	1.674	1.00
531_F	569_F	1.658	1.00
154_G	159_M	1.653	1.00
406_P	436_D	1.650	1.00
340_R	385_E	1.641	1.00
333_H	392_H	1.631	1.00
145_R	148_Y	1.625	1.00
6_L	42_E	1.610	1.00
619_M	623_I	1.608	1.00
337_A	341_N	1.606	1.00
556_A	586_V	1.602	1.00
523_G	591_L	1.600	1.00
197_I	217_I	1.593	1.00
308_M	393_F	1.589	1.00
482_D	485_K	1.588	1.00
134_R	162_C	1.575	1.00
3_H	6_L	1.575	1.00
510_E	573_C	1.573	1.00
57_V	60_S	1.564	1.00
131_V	142_M	1.562	1.00
220_I	275_I	1.562	1.00
515_K	581_W	1.554	0.99
307_A	376_Q	1.547	0.99
141_V	153_R	1.536	0.99
568_T	595_E	1.529	0.99
407_K	490_L	1.529	0.99
215_N	278_H	1.524	0.99
309_I	327_K	1.522	0.99
348_R	384_N	1.518	0.99
522_L	571_A	1.517	0.99
532_A	536_I	1.517	0.99
312_V	393_F	1.507	0.99
55_Q	63_K	1.496	0.99
89_L	92_E	1.489	0.99
349_N	384_N	1.488	0.99
520_Q	541_F	1.486	0.99
312_V	366_G	1.482	0.99
431_F	487_E	1.482	0.99
12_L	29_L	1.476	0.99
580_D	583_S	1.472	0.99
52_A	66_I	1.469	0.99
40_I	62_Y	1.452	0.99
326_L	330_L	1.444	0.99
111_D	121_K	1.442	0.99
40_I	54_V	1.441	0.99
554_L	587_Q	1.441	0.99
23_S	33_T	1.439	0.99
508_F	574_T	1.437	0.99
253_E	272_T	1.431	0.99
442_E	445_S	1.429	0.99
509_Q	576_K	1.428	0.99
326_L	396_A	1.425	0.99
164_A	219_H	1.418	0.99
248_E	276_T	1.412	0.99
532_A	593_C	1.401	0.99
93_R	123_T	1.400	0.99
98_M	135_L	1.398	0.99
330_L	389_L	1.397	0.99
413_C	461_I	1.393	0.99
505_L	529_C	1.392	0.99
325_E	399_R	1.389	0.99
626_R	630_E	1.388	0.99
486_I	490_L	1.387	0.99
516_E	520_Q	1.386	0.99
107_Y	151_K	1.384	0.99
478_L	486_I	1.380	0.99
10_L	43_L	1.374	0.99
215_N	219_H	1.369	0.99
544_E	549_T	1.367	0.99
313_D	323_D	1.365	0.99
507_F	525_K	1.362	0.99
337_A	340_R	1.358	0.99
140_I	159_M	1.357	0.99
512_L	518_V	1.357	0.99
527_V	537_I	1.354	0.99
9_I	25_F	1.349	0.99
410_I	454_I	1.348	0.99
439_G	454_I	1.347	0.99
196_A	200_K	1.345	0.99
34_R	38_N	1.345	0.99
164_A	222_I	1.341	0.98
458_I	474_V	1.338	0.98
19_P	61_G	1.337	0.98
526_V	532_A	1.335	0.98
204_D	254_A	1.332	0.98
458_I	472_L	1.327	0.98
549_T	581_W	1.322	0.98
23_S	27_A	1.321	0.98
501_L	572_V	1.315	0.98
22_S	62_Y	1.314	0.98
200_K	255_I	1.313	0.98
570_W	590_C	1.307	0.98
513_R	517_E	1.302	0.98
530_G	566_K	1.300	0.98
459_S	473_K	1.295	0.98
415_S	419_S	1.294	0.98
506_V	631_L	1.292	0.98
252_A	276_T	1.285	0.98
550_C	581_W	1.285	0.98
527_V	534_E	1.281	0.98
249_Y	276_T	1.281	0.98
268_P	271_E	1.280	0.98
523_G	540_I	1.276	0.98
233_V	274_Y	1.273	0.98
146_P	149_G	1.273	0.98
537_I	541_F	1.271	0.98
113_L	124_L	1.270	0.98
6_L	39_D	1.268	0.98
94_M	130_E	1.263	0.98
570_W	605_M	1.260	0.98
316_L	365_A	1.255	0.98
192_I	262_K	1.254	0.98
510_E	576_K	1.253	0.98
416_G	419_S	1.247	0.98
362_A	366_G	1.243	0.98
326_L	399_R	1.238	0.97
434_R	487_E	1.238	0.97
362_A	394_G	1.237	0.97
326_L	369_A	1.234	0.97
6_L	43_L	1.231	0.97
506_V	574_T	1.229	0.97
574_T	588_F	1.225	0.97
31_V	35_T	1.223	0.97
454_I	469_V	1.221	0.97
628_Y	632_S	1.218	0.97
90_P	127_D	1.218	0.97
398_E	426_K	1.216	0.97
227_I	271_E	1.215	0.97
320_I	396_A	1.212	0.97
625_C	634_V	1.211	0.97
143_E	151_K	1.208	0.97
109_K	112_E	1.205	0.97
26_A	31_V	1.204	0.97
352_L	383_E	1.204	0.97
26_A	33_T	1.204	0.97
156_E	271_E	1.201	0.97
252_A	279_L	1.197	0.97
408_R	453_S	1.194	0.97
201_M	208_L	1.186	0.97
97_L	131_V	1.186	0.97
12_L	16_A	1.181	0.97
34_R	394_G	1.181	0.97
363_F	383_E	1.177	0.97
96_Y	117_L	1.173	0.96
94_M	127_D	1.172	0.96
536_I	593_C	1.167	0.96
489_I	493_E	1.164	0.96
13_L	64_L	1.163	0.96
580_D	585_R	1.161	0.96
316_L	320_I	1.160	0.96
26_A	36_V	1.159	0.96
246_Q	249_Y	1.158	0.96
90_P	130_E	1.157	0.96
427_L	435_L	1.156	0.96
523_G	527_V	1.155	0.96
329_G	399_R	1.154	0.96
253_E	269_K	1.149	0.96
301_T	305_T	1.146	0.96
414_A	461_I	1.146	0.96
588_F	623_I	1.144	0.96
193_I	221_A	1.140	0.96
517_E	520_Q	1.138	0.96
430_H	487_E	1.138	0.96
515_K	582_E	1.137	0.96
98_M	166_Y	1.134	0.96
349_N	388_Y	1.132	0.96
628_Y	631_L	1.131	0.96
519_I	523_G	1.130	0.96
309_I	326_L	1.126	0.96
32_T	35_T	1.123	0.95
575_L	587_Q	1.122	0.95
568_T	594_V	1.120	0.95
110_L	121_K	1.112	0.95
519_I	540_I	1.107	0.95
472_L	482_D	1.106	0.95
35_T	38_N	1.104	0.95
249_Y	272_T	1.103	0.95
240_M	273_A	1.102	0.95
416_G	420_A	1.101	0.95
3_H	42_E	1.099	0.95
158_Q	161_Y	1.092	0.95
512_L	575_L	1.091	0.95
501_L	506_V	1.089	0.95
363_F	367_I	1.087	0.95
373_I	381_I	1.080	0.94
109_K	149_G	1.073	0.94
194_R	213_L	1.068	0.94
521_F	525_K	1.067	0.94
396_A	399_R	1.063	0.94
409_C	490_L	1.062	0.94
123_T	127_D	1.062	0.94
542_E	545_D	1.057	0.94
334_M	337_A	1.055	0.94
111_D	115_E	1.054	0.94
519_I	541_F	1.052	0.94
96_Y	116_E	1.050	0.94
430_H	483_F	1.048	0.93
602_L	606_Y	1.048	0.93
581_W	589_V	1.047	0.93
38_N	42_E	1.043	0.93
227_I	267_F	1.042	0.93
252_A	272_T	1.042	0.93
114_A	124_L	1.036	0.93
102_L	162_C	1.036	0.93
194_R	214_N	1.035	0.93
210_N	442_E	1.033	0.93
581_W	586_V	1.030	0.93
243_I	249_Y	1.019	0.92
156_E	230_E	1.019	0.92
138_Y	162_C	1.014	0.92
625_C	631_L	1.010	0.92
413_C	418_G	1.008	0.92
572_V	631_L	1.008	0.92
308_M	366_G	1.006	0.92
605_M	609_L	1.006	0.92
395_A	399_R	1.002	0.92
310_K	321_L	0.994	0.92
305_T	331_A	0.992	0.91
595_E	598_N	0.990	0.91
413_C	442_E	0.989	0.91
93_R	119_I	0.988	0.91
525_K	571_A	0.987	0.91
122_S	125_Q	0.986	0.91
196_A	255_I	0.985	0.91
549_T	558_P	0.983	0.91
366_G	370_G	0.981	0.91
219_H	223_A	0.980	0.91
109_K	148_Y	0.978	0.91
16_A	20_V	0.978	0.91
56_S	62_Y	0.977	0.91
576_K	626_R	0.977	0.91
274_Y	350_P	0.977	0.91
507_F	571_A	0.976	0.91
535_E	538_D	0.974	0.91
9_I	43_L	0.974	0.91
281_G	336_P	0.974	0.91
431_F	483_F	0.972	0.91
373_I	377_T	0.971	0.91
124_L	127_D	0.970	0.91
556_A	581_W	0.970	0.91
532_A	537_I	0.969	0.90
539_S	542_E	0.967	0.90
226_R	271_E	0.967	0.90
392_H	395_A	0.966	0.90
256_V	275_I	0.963	0.90
423_L	478_L	0.959	0.90
118_F	581_W	0.958	0.90
333_H	559_H	0.955	0.90
539_S	560_P	0.955	0.90
554_L	623_I	0.955	0.90
459_S	471_V	0.954	0.90
248_E	280_L	0.952	0.90
519_I	591_L	0.950	0.90
276_T	280_L	0.947	0.89
21_T	26_A	0.942	0.89
309_I	393_F	0.941	0.89
502_K	505_L	0.941	0.89
209_S	283_K	0.939	0.89
308_M	372_V	0.938	0.89
625_C	630_E	0.937	0.89
311_A	314_R	0.935	0.89
350_P	388_Y	0.934	0.89
560_P	593_C	0.933	0.89
252_A	256_V	0.927	0.88
9_I	20_V	0.926	0.88
310_K	314_R	0.925	0.88
225_K	229_T	0.925	0.88
305_T	309_I	0.924	0.88
327_K	331_A	0.924	0.88
252_A	255_I	0.921	0.88
144_T	150_F	0.919	0.88
392_H	418_G	0.917	0.88
124_L	131_V	0.916	0.88
424_R	440_T	0.916	0.88
29_L	36_V	0.916	0.88
537_I	540_I	0.916	0.88
407_K	456_F	0.915	0.88
333_H	385_E	0.914	0.88
333_H	388_Y	0.910	0.87
507_F	521_F	0.909	0.87
512_L	573_C	0.908	0.87
121_K	149_G	0.907	0.87
509_Q	575_L	0.904	0.87
330_L	392_H	0.902	0.87
561_L	594_V	0.898	0.87
439_G	449_M	0.897	0.87
590_C	609_L	0.896	0.87
52_A	64_L	0.895	0.87
612_I	622_L	0.895	0.87
135_L	140_I	0.893	0.86
550_C	603_Q	0.892	0.86
588_F	619_M	0.892	0.86
536_I	560_P	0.888	0.86
536_I	540_I	0.888	0.86
337_A	381_I	0.888	0.86
66_I	72_F	0.884	0.86
505_L	531_F	0.884	0.86
354_A	358_H	0.882	0.86
521_F	524_Q	0.881	0.86
308_M	369_A	0.879	0.86
366_G	369_A	0.879	0.86
413_C	460_T	0.876	0.85
54_V	57_V	0.873	0.85
412_V	463_I	0.872	0.85
476_T	482_D	0.872	0.85
506_V	572_V	0.870	0.85
516_E	541_F	0.868	0.85
371_I	374_K	0.862	0.84
456_F	486_I	0.860	0.84
384_N	387_G	0.859	0.84
336_P	340_R	0.856	0.84
4_G	8_D	0.855	0.84
526_V	569_F	0.855	0.84
154_G	226_R	0.855	0.84
518_V	522_L	0.853	0.84
370_G	381_I	0.847	0.83
338_I	342_R	0.846	0.83
484_T	487_E	0.842	0.83
615_D	618_A	0.842	0.83
515_K	541_F	0.841	0.83
22_S	61_G	0.841	0.83
233_V	271_E	0.840	0.83
305_T	327_K	0.838	0.83
114_A	150_F	0.837	0.83
131_V	135_L	0.836	0.83
550_C	584_Q	0.832	0.82
598_N	601_D	0.832	0.82
474_V	478_L	0.832	0.82
560_P	564_Q	0.829	0.82
408_R	438_L	0.828	0.82
249_Y	273_A	0.825	0.82
128_L	131_V	0.825	0.82
501_L	505_L	0.824	0.82
426_K	477_I	0.823	0.82
560_P	565_T	0.823	0.82
338_I	379_I	0.823	0.82
419_S	461_I	0.820	0.81
508_F	576_K	0.820	0.81
200_K	258_E	0.818	0.81
275_I	278_H	0.814	0.81
347_L	388_Y	0.812	0.81
243_I	273_A	0.812	0.81
535_E	564_Q	0.811	0.81
389_L	418_G	0.811	0.81
441_A	449_M	0.809	0.81
200_K	251_A	0.808	0.80
536_I	541_F	0.805	0.80
522_L	525_K	0.805	0.80
398_E	401_K	0.802	0.80
280_L	339_S	0.801	0.80
505_L	571_A	0.801	0.80
427_L	458_I	0.800	0.80
304_L	308_M	0.799	0.80
446_L	465_K	0.799	0.80
370_G	386_I	0.798	0.80
13_L	62_Y	0.798	0.80
223_A	227_I	0.796	0.79
415_S	418_G	0.796	0.79
186_P	189_E	0.795	0.79
550_C	582_E	0.794	0.79
513_R	577_K	0.792	0.79
349_N	356_K	0.790	0.79
107_Y	148_Y	0.790	0.79
121_K	125_Q	0.788	0.79
249_Y	253_E	0.787	0.79
3_H	39_D	0.786	0.79
219_H	392_H	0.786	0.79
620_N	623_I	0.785	0.79
98_M	152_L	0.785	0.79
309_I	312_V	0.785	0.79
629_Q	633_D	0.783	0.78
369_A	372_V	0.782	0.78
9_I	29_L	0.778	0.78
413_C	417_A	0.776	0.78
198_L	213_L	0.775	0.78
621_Q	624_K	0.774	0.78
362_A	397_I	0.774	0.78
449_M	454_I	0.773	0.77
329_G	395_A	0.773	0.77
341_N	382_H	0.770	0.77
612_I	618_A	0.770	0.77
340_R	347_L	0.765	0.77
376_Q	379_I	0.765	0.77
249_Y	269_K	0.764	0.77
38_N	41_K	0.762	0.76
268_P	278_H	0.759	0.76
347_L	384_N	0.758	0.76
282_T	337_A	0.757	0.76
13_L	43_L	0.756	0.76
109_K	121_K	0.756	0.76
392_H	399_R	0.755	0.76
526_V	571_A	0.754	0.76
70_Q	74_T	0.754	0.76
409_C	437_I	0.752	0.75
350_P	355_I	0.752	0.75
102_L	140_I	0.750	0.75
201_M	444_Y	0.748	0.75
515_K	547_S	0.746	0.75
553_N	581_W	0.745	0.75
40_I	56_S	0.745	0.75
337_A	382_H	0.744	0.75
58_R	61_G	0.743	0.75
256_V	272_T	0.743	0.75
561_L	603_Q	0.741	0.74
543_R	559_H	0.740	0.74
594_V	606_Y	0.739	0.74
349_N	386_I	0.738	0.74
281_G	392_H	0.737	0.74
415_S	420_A	0.737	0.74
351_M	388_Y	0.736	0.74
539_S	564_Q	0.736	0.74
256_V	260_E	0.734	0.74
541_F	549_T	0.733	0.74
302_D	331_A	0.731	0.73
337_A	345_M	0.731	0.73
539_S	561_L	0.731	0.73
9_I	39_D	0.731	0.73
16_A	24_F	0.730	0.73
109_K	147_N	0.728	0.73
121_K	418_G	0.728	0.73
630_E	633_D	0.727	0.73
244_L	249_Y	0.724	0.73
107_Y	149_G	0.724	0.73
320_I	397_I	0.724	0.73
87_P	96_Y	0.723	0.73
128_L	132_K	0.723	0.73
154_G	160_R	0.722	0.72
19_P	60_S	0.722	0.72
219_H	222_I	0.721	0.72
423_L	483_F	0.719	0.72
476_T	565_T	0.716	0.72
540_I	560_P	0.715	0.72
369_A	393_F	0.715	0.72
622_L	631_L	0.714	0.72
478_L	482_D	0.714	0.72
409_C	456_F	0.713	0.72
109_K	146_P	0.713	0.72
108_L	113_L	0.712	0.71
21_T	24_F	0.712	0.71
341_N	385_E	0.712	0.71
324_K	328_I	0.712	0.71
257_K	260_E	0.711	0.71
329_G	421_Q	0.711	0.71
411_I	424_R	0.709	0.71
478_L	483_F	0.708	0.71
416_G	422_L	0.707	0.71
515_K	543_R	0.707	0.71
5_R	31_V	0.707	0.71
126_T	129_K	0.706	0.71
550_C	586_V	0.705	0.71
87_P	92_E	0.705	0.71
522_L	540_I	0.704	0.71
502_K	570_W	0.703	0.70
344_G	379_I	0.703	0.70
431_F	440_T	0.703	0.70
341_N	379_I	0.703	0.70
526_V	536_I	0.703	0.70
609_L	613_L	0.702	0.70
408_R	439_G	0.701	0.70
136_L	141_V	0.701	0.70
419_S	547_S	0.701	0.70
57_V	61_G	0.700	0.70
52_A	75_L	0.700	0.70
515_K	550_C	0.697	0.70
155_D	406_P	0.696	0.70
606_Y	610_G	0.696	0.70
21_T	61_G	0.695	0.70
249_Y	280_L	0.695	0.70
426_K	430_H	0.694	0.70
311_A	369_A	0.694	0.70
66_I	71_V	0.693	0.69
349_N	359_Y	0.692	0.69
575_L	579_I	0.692	0.69
520_Q	538_D	0.690	0.69
142_M	382_H	0.690	0.69
301_T	331_A	0.689	0.69
540_I	549_T	0.687	0.69
364_E	367_I	0.686	0.69
196_A	258_E	0.685	0.69
94_M	134_R	0.684	0.68
505_L	509_Q	0.683	0.68
65_R	68_D	0.683	0.68
503_K	628_Y	0.683	0.68
620_N	624_K	0.681	0.68
135_L	152_L	0.678	0.68
185_L	221_A	0.678	0.68
110_L	124_L	0.676	0.67
313_D	321_L	0.676	0.67
387_G	390_A	0.674	0.67
416_G	461_I	0.674	0.67
96_Y	100_R	0.673	0.67
44_Q	62_Y	0.672	0.67
230_E	271_E	0.672	0.67
32_T	313_D	0.672	0.67
443_Y	461_I	0.672	0.67
101_L	152_L	0.672	0.67
126_T	420_A	0.671	0.67
233_V	475_N	0.671	0.67
125_Q	150_F	0.671	0.67
413_C	419_S	0.670	0.67
165_E	387_G	0.670	0.67
484_T	488_S	0.668	0.67
355_I	390_A	0.668	0.67
365_A	369_A	0.668	0.67
34_R	61_G	0.664	0.66
209_S	212_G	0.663	0.66
221_A	225_K	0.663	0.66
333_H	355_I	0.662	0.66
255_I	332_L	0.661	0.66
552_G	581_W	0.660	0.66
507_F	589_V	0.657	0.65
598_N	602_L	0.655	0.65
543_R	591_L	0.655	0.65
543_R	560_P	0.655	0.65
569_F	593_C	0.655	0.65
594_V	602_L	0.654	0.65
250_Q	253_E	0.654	0.65
474_V	482_D	0.652	0.65
109_K	125_Q	0.652	0.65
515_K	549_T	0.651	0.65
37_R	610_G	0.651	0.65
260_E	267_F	0.651	0.65
513_R	575_L	0.650	0.64
525_K	528_E	0.650	0.64
56_S	61_G	0.649	0.64
511_D	528_E	0.648	0.64
167_I	386_I	0.648	0.64
577_K	587_Q	0.648	0.64
572_V	590_C	0.648	0.64
484_T	577_K	0.648	0.64
549_T	553_N	0.647	0.64
125_Q	144_T	0.647	0.64
148_Y	387_G	0.647	0.64
271_E	388_Y	0.646	0.64
320_I	323_D	0.645	0.64
340_R	349_N	0.644	0.64
249_Y	252_A	0.644	0.64
323_D	398_E	0.643	0.64
565_T	631_L	0.643	0.64
514_S	520_Q	0.643	0.64
260_E	263_L	0.642	0.64
528_E	629_Q	0.642	0.64
109_K	145_R	0.642	0.64
94_M	117_L	0.642	0.64
311_A	315_E	0.641	0.63
457_V	469_V	0.640	0.63
202_K	205_R	0.640	0.63
550_C	583_S	0.640	0.63
543_R	558_P	0.639	0.63
188_E	221_A	0.639	0.63
98_M	309_I	0.639	0.63
189_E	192_I	0.639	0.63
74_T	77_Q	0.637	0.63
34_R	39_D	0.637	0.63
574_T	631_L	0.637	0.63
534_E	538_D	0.637	0.63
100_R	117_L	0.637	0.63
511_D	624_K	0.633	0.62
546_M	549_T	0.632	0.62
355_I	387_G	0.632	0.62
510_E	575_L	0.631	0.62
305_T	308_M	0.631	0.62
196_A	199_K	0.629	0.62
171_R	320_I	0.628	0.62
26_A	61_G	0.628	0.62
120_S	123_T	0.627	0.62
235_L	270_D	0.627	0.62
396_A	400_K	0.625	0.61
592_L	610_G	0.624	0.61
260_E	272_T	0.624	0.61
190_I	221_A	0.624	0.61
509_Q	513_R	0.621	0.61
160_R	222_I	0.620	0.61
427_L	486_I	0.620	0.61
243_I	276_T	0.620	0.61
393_F	443_Y	0.619	0.61
278_H	345_M	0.619	0.61
552_G	584_Q	0.617	0.60
218_I	431_F	0.617	0.60
525_K	573_C	0.616	0.60
252_A	275_I	0.614	0.60
34_R	62_Y	0.614	0.60
101_L	186_P	0.612	0.60
532_A	565_T	0.612	0.60
543_R	581_W	0.611	0.60
6_L	86_L	0.611	0.60
38_N	121_K	0.611	0.60
539_S	547_S	0.610	0.60
350_P	387_G	0.610	0.60
588_F	631_L	0.610	0.60
109_K	432_G	0.608	0.59
578_P	585_R	0.608	0.59
162_C	166_Y	0.608	0.59
117_L	124_L	0.607	0.59
103_L	159_M	0.607	0.59
256_V	265_V	0.607	0.59
315_E	365_A	0.607	0.59
13_L	26_A	0.606	0.59
312_V	317_K	0.605	0.59
123_T	474_V	0.603	0.59
566_K	569_F	0.603	0.59
278_H	281_G	0.603	0.59
489_I	492_D	0.601	0.58
196_A	259_L	0.600	0.58
160_R	223_A	0.598	0.58
413_C	423_L	0.598	0.58
304_L	373_I	0.597	0.58
337_A	347_L	0.597	0.58
77_Q	517_E	0.597	0.58
388_Y	418_G	0.596	0.58
90_P	93_R	0.596	0.58
352_L	384_N	0.595	0.58
267_F	275_I	0.595	0.58
129_K	144_T	0.595	0.58
240_M	270_D	0.594	0.58
565_T	569_F	0.594	0.58
518_V	525_K	0.594	0.58
426_K	546_M	0.593	0.57
189_E	225_K	0.593	0.57
536_I	558_P	0.593	0.57
31_V	40_I	0.592	0.57
53_F	65_R	0.592	0.57
621_Q	630_E	0.592	0.57
31_V	312_V	0.591	0.57
431_F	494_K	0.589	0.57
22_S	26_A	0.589	0.57
140_I	627_S	0.587	0.57
474_V	547_S	0.587	0.57
38_N	536_I	0.583	0.56
211_M	281_G	0.581	0.56
557_I	570_W	0.581	0.56
304_L	376_Q	0.581	0.56
325_E	329_G	0.581	0.56
509_Q	573_C	0.580	0.56
314_R	317_K	0.578	0.56
507_F	573_C	0.578	0.56
354_A	357_E	0.578	0.56
131_V	152_L	0.577	0.55
228_R	264_S	0.576	0.55
40_I	459_S	0.576	0.55
140_I	162_C	0.576	0.55
149_G	416_G	0.575	0.55
522_L	581_W	0.574	0.55
200_K	254_A	0.574	0.55
603_Q	606_Y	0.573	0.55
212_G	282_T	0.573	0.55
413_C	459_S	0.572	0.55
530_G	533_D	0.570	0.55
366_G	389_L	0.569	0.54
370_G	390_A	0.569	0.54
341_N	381_I	0.569	0.54
428_R	432_G	0.569	0.54
310_K	380_E	0.569	0.54
329_G	392_H	0.568	0.54
308_M	370_G	0.568	0.54
5_R	9_I	0.568	0.54
227_I	268_P	0.567	0.54
280_L	457_V	0.566	0.54
301_T	376_Q	0.566	0.54
612_I	623_I	0.566	0.54
336_P	339_S	0.565	0.54
251_A	255_I	0.565	0.54
329_G	396_A	0.565	0.54
337_A	389_L	0.565	0.54
518_V	579_I	0.564	0.54
446_L	457_V	0.563	0.54
246_Q	276_T	0.563	0.54
438_L	454_I	0.562	0.53
524_Q	527_V	0.562	0.53
507_F	522_L	0.561	0.53
130_E	133_K	0.561	0.53
8_D	12_L	0.561	0.53
503_K	632_S	0.560	0.53
355_I	373_I	0.560	0.53
316_L	565_T	0.560	0.53
470_P	489_I	0.559	0.53
426_K	475_N	0.559	0.53
515_K	532_A	0.557	0.53
193_I	259_L	0.557	0.53
408_R	455_D	0.557	0.53
547_S	606_Y	0.557	0.53
233_V	252_A	0.556	0.53
45_G	49_G	0.555	0.53
509_Q	566_K	0.554	0.52
540_I	610_G	0.554	0.52
216_L	415_S	0.553	0.52
193_I	196_A	0.553	0.52
208_L	279_L	0.553	0.52
503_K	622_L	0.553	0.52
547_S	561_L	0.552	0.52
43_L	54_V	0.551	0.52
551_F	612_I	0.551	0.52
500_Y	503_K	0.551	0.52
59_G	347_L	0.551	0.52
210_N	444_Y	0.550	0.52
406_P	422_L	0.550	0.52
95_A	169_D	0.549	0.52
359_Y	426_K	0.549	0.52
48_S	53_F	0.548	0.52
249_Y	423_L	0.548	0.52
243_I	280_L	0.547	0.52
526_V	531_F	0.547	0.52
142_M	610_G	0.546	0.51
16_A	19_P	0.545	0.51
197_I	612_I	0.545	0.51
248_E	281_G	0.545	0.51
302_D	327_K	0.545	0.51
410_I	449_M	0.545	0.51
24_F	28_Q	0.544	0.51
138_Y	158_Q	0.544	0.51
150_F	312_V	0.544	0.51
362_A	365_A	0.543	0.51
506_V	567_T	0.543	0.51
394_G	417_A	0.543	0.51
363_F	387_G	0.543	0.51
74_T	258_E	0.543	0.51
46_V	50_H	0.542	0.51
313_D	320_I	0.540	0.51
540_I	581_W	0.540	0.51
161_Y	561_L	0.540	0.51
12_L	411_I	0.539	0.50
283_K	421_Q	0.539	0.50
540_I	593_C	0.539	0.50
472_L	486_I	0.539	0.50
278_H	336_P	0.538	0.50
42_E	45_G	0.538	0.50
517_E	521_F	0.538	0.50
570_W	609_L	0.538	0.50
438_L	626_R	0.537	0.50
572_V	605_M	0.537	0.50
140_I	178_L	0.537	0.50
609_L	635_F	0.537	0.50
248_E	252_A	0.536	0.50
454_I	471_V	0.536	0.50
213_L	217_I	0.536	0.50
549_T	606_Y	0.536	0.50
394_G	398_E	0.536	0.50
34_R	37_R	0.535	0.50
215_N	349_N	0.535	0.50
212_G	285_M	0.535	0.50
128_L	150_F	0.535	0.50
498_N	631_L	0.535	0.50
330_L	396_A	0.534	0.50
22_S	37_R	0.534	0.50
238_K	453_S	0.534	0.50
9_I	327_K	0.533	0.50
116_E	438_L	0.532	0.50
52_A	72_F	0.532	0.50
352_L	363_F	0.531	0.49
549_T	594_V	0.530	0.49
108_L	344_G	0.530	0.49
322_H	400_K	0.530	0.49
155_D	234_S	0.529	0.49
125_Q	388_Y	0.528	0.49
561_L	565_T	0.528	0.49
47_L	52_A	0.528	0.49
540_I	601_D	0.527	0.49
312_V	362_A	0.527	0.49
37_R	444_Y	0.527	0.49
70_Q	269_K	0.526	0.49
414_A	443_Y	0.526	0.49
605_M	608_L	0.525	0.49
581_W	584_Q	0.523	0.48
395_A	437_I	0.523	0.48
505_L	570_W	0.523	0.48
206_I	251_A	0.522	0.48
41_K	62_Y	0.522	0.48
315_E	369_A	0.521	0.48
573_C	591_L	0.521	0.48
246_Q	280_L	0.520	0.48
581_W	595_E	0.520	0.48
510_E	513_R	0.519	0.48
537_I	560_P	0.518	0.48
274_Y	346_N	0.517	0.48
128_L	142_M	0.517	0.48
330_L	575_L	0.517	0.48
124_L	494_K	0.517	0.48
26_A	283_K	0.516	0.48
460_T	476_T	0.516	0.48
142_M	250_Q	0.516	0.48
329_G	394_G	0.514	0.47
458_I	493_E	0.514	0.47
369_A	396_A	0.514	0.47
274_Y	546_M	0.514	0.47
423_L	474_V	0.514	0.47
458_I	489_I	0.514	0.47
498_N	634_V	0.513	0.47
568_T	601_D	0.513	0.47
224_C	233_V	0.513	0.47
476_T	479_G	0.513	0.47
326_L	329_G	0.512	0.47
329_G	424_R	0.512	0.47
548_P	555_V	0.512	0.47
356_K	547_S	0.512	0.47
31_V	38_N	0.512	0.47
367_I	547_S	0.512	0.47
551_F	594_V	0.511	0.47
592_L	613_L	0.511	0.47
8_D	29_L	0.511	0.47
504_E	508_F	0.511	0.47
222_I	373_I	0.510	0.47
114_A	119_I	0.510	0.47
141_V	353_A	0.509	0.47
391_L	395_A	0.509	0.47
64_L	589_V	0.509	0.47
428_R	480_G	0.507	0.46
594_V	603_Q	0.506	0.46
329_G	474_V	0.506	0.46
24_F	27_A	0.506	0.46
528_E	531_F	0.506	0.46
253_E	305_T	0.505	0.46
146_P	409_C	0.505	0.46
197_I	201_M	0.504	0.46
521_F	573_C	0.504	0.46
398_E	429_S	0.504	0.46
110_L	114_A	0.503	0.46
590_C	593_C	0.503	0.46
64_L	69_E	0.503	0.46
109_K	144_T	0.503	0.46
136_L	266_T	0.502	0.46
562_V	565_T	0.502	0.46
132_K	136_L	0.502	0.46
37_R	152_L	0.502	0.46
34_R	246_Q	0.502	0.46
106_H	462_P	0.502	0.46
395_A	398_E	0.501	0.46
417_A	420_A	0.501	0.46
536_I	565_T	0.501	0.46
97_L	268_P	0.501	0.46
336_P	347_L	0.501	0.46
346_N	387_G	0.501	0.46
309_I	501_L	0.500	0.45
160_R	274_Y	0.500	0.45

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r6iA	2	0.7145	100	0.434	Contact Map
3sqnA	2	0.7083	100	0.488	Contact Map
1h99A	2	0.3417	100	0.764	Contact Map
1a6jA	4	0.2371	100	0.788	Contact Map
3oxpA	2	0.2215	100	0.788	Contact Map
2a0jA	1	0.2215	100	0.79	Contact Map
3bjvA	2	0.2278	100	0.792	Contact Map
2oqtA	2	0.2293	100	0.793	Contact Map
3urrA	2	0.2309	100	0.793	Contact Map
2oq3A	1	0.2215	100	0.793	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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