GREMLIN Database
HTPG - Chaperone protein HtpG
UniProt: P46208 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 626 (601)
Sequences: 2939 (1617)
Seq/√Len: 66.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
143_E159_P5.5151.00
71_R183_D5.3831.00
76_S168_D5.0531.00
135_I170_I5.0421.00
372_D375_K4.7691.00
91_L134_V4.5001.00
438_G444_I4.3221.00
252_E264_K4.0511.00
131_V148_E3.8521.00
68_K187_E3.7861.00
184_E190_R3.6981.00
510_K514_E3.4081.00
516_M596_T3.4011.00
67_D70_A3.3651.00
425_R459_E3.3571.00
601_N620_N3.2581.00
421_E424_S3.2481.00
87_L136_S3.2011.00
61_Y207_K3.0591.00
246_L250_D3.0571.00
135_I146_K3.0311.00
517_K526_N3.0291.00
477_S480_E3.0251.00
64_V195_I3.0011.00
420_D478_Y2.9961.00
420_D479_Q2.9581.00
256_A264_K2.9351.00
133_T148_E2.9221.00
507_S510_K2.8301.00
514_E518_N2.8141.00
192_K230_Q2.7801.00
87_L145_Y2.7771.00
190_R193_A2.7471.00
83_T138_A2.7151.00
130_D175_E2.7021.00
412_K457_G2.6741.00
176_N183_D2.6401.00
500_K503_E2.6011.00
411_S459_E2.5941.00
33_I195_I2.5871.00
404_D420_D2.5871.00
594_L623_K2.5531.00
135_I160_C2.5431.00
85_D89_Q2.5401.00
135_I168_D2.4921.00
25_K177_T2.4911.00
86_E138_A2.4601.00
144_A160_C2.4571.00
106_N109_K2.3921.00
417_V425_R2.3641.00
441_Y445_E2.3601.00
195_I232_V2.3521.00
503_E507_S2.3411.00
146_K158_E2.3381.00
131_V172_K2.3321.00
403_K475_L2.3031.00
65_A76_S2.2931.00
133_T172_K2.2821.00
410_S461_L2.2711.00
188_E192_K2.2701.00
411_S462_Y2.2341.00
2_A84_K2.2221.00
247_T250_D2.1981.00
40_I60_Y2.1881.00
330_V357_I2.1661.00
516_M571_I2.1171.00
248_D268_H2.0941.00
130_D172_K2.0551.00
613_D616_E2.0481.00
101_A104_K2.0401.00
66_A191_L2.0151.00
46_K138_A2.0071.00
369_L407_L1.9951.00
524_V527_V1.9941.00
63_K229_E1.9851.00
173_I186_L1.9791.00
495_T499_Q1.9691.00
506_E510_K1.9611.00
207_K231_T1.9431.00
518_N521_S1.9401.00
432_F482_E1.9261.00
209_D229_E1.9061.00
133_T146_K1.9051.00
432_F484_K1.8881.00
248_D252_E1.8861.00
249_E253_K1.8821.00
252_E268_H1.8521.00
378_T381_K1.8391.00
131_V150_A1.8271.00
125_A132_V1.8211.00
63_K207_K1.8171.00
477_S482_E1.8111.00
453_V486_V1.8081.00
74_T168_D1.8061.00
503_E506_E1.7891.00
26_E190_R1.7751.00
407_L418_S1.7451.00
162_K168_D1.7301.00
106_N110_D1.7291.00
420_D424_S1.7171.00
288_N382_S1.7150.99
369_L418_S1.7140.99
523_K597_N1.7130.99
500_K504_E1.7030.99
263_D288_N1.6970.99
420_D423_V1.6950.99
238_I246_L1.6850.99
410_S417_V1.6840.99
497_E500_K1.6650.99
410_S459_E1.6560.99
427_P457_G1.6370.99
374_E378_T1.6340.99
423_V479_Q1.6280.99
501_Q504_E1.6280.99
394_D398_N1.6210.99
133_T170_I1.6050.99
287_E378_T1.6000.99
423_V481_K1.5980.99
12_R100_L1.5950.99
107_E110_D1.5900.99
417_V459_E1.5890.99
148_E156_T1.5870.99
63_K76_S1.5850.99
136_S157_I1.5790.99
519_I596_T1.5780.99
426_M481_K1.5670.99
96_K101_A1.5660.99
129_A171_L1.5620.99
593_S597_N1.5500.99
252_E265_P1.5410.99
377_E415_K1.5400.99
144_A163_D1.5360.99
373_R377_E1.5270.99
326_V361_I1.5270.99
619_N623_K1.5270.99
89_Q101_A1.5270.99
375_K378_T1.5150.99
75_I169_I1.5120.99
251_Y270_H1.5070.99
409_Y416_L1.5000.99
404_D479_Q1.4980.99
130_D174_K1.4980.99
373_R421_E1.4970.99
72_T170_I1.4940.99
450_T486_V1.4930.99
255_Y261_G1.4920.99
367_S371_K1.4910.99
99_S114_I1.4900.99
29_L75_I1.4780.98
209_D227_Q1.4760.98
64_V73_L1.4620.98
404_D478_Y1.4610.98
87_L91_L1.4500.98
578_F599_L1.4490.98
68_K186_L1.4470.98
207_K229_E1.4380.98
64_V232_V1.4360.98
125_A171_L1.4300.98
26_E185_F1.4270.98
241_K250_D1.4150.98
549_E552_K1.3980.98
299_E316_A1.3930.98
32_L171_L1.3920.98
86_E89_Q1.3840.98
472_I483_F1.3740.98
136_S145_Y1.3690.97
515_E592_L1.3660.97
400_D403_K1.3590.97
3_K156_T1.3520.97
272_S280_N1.3510.97
144_A162_K1.3500.97
40_I204_Y1.3500.97
83_T86_E1.3410.97
453_V491_L1.3360.97
56_D59_S1.3240.97
551_E567_K1.3230.97
285_V365_L1.3130.97
504_E508_K1.3080.97
21_I339_I1.3080.97
68_K188_E1.3060.97
366_Q404_D1.3010.97
411_S425_R1.2960.96
242_N245_E1.2920.96
365_L376_Y1.2860.96
84_K159_P1.2810.96
323_F362_K1.2740.96
319_L357_I1.2620.96
46_K50_D1.2620.96
409_Y414_K1.2610.96
412_K427_P1.2600.96
253_K256_A1.2560.96
104_K108_L1.2530.96
71_R175_E1.2400.95
597_N620_N1.2360.95
264_K287_E1.2350.95
104_K107_E1.2350.95
496_D499_Q1.2270.95
504_E507_S1.2240.95
571_I578_F1.2210.95
253_K257_E1.2180.95
18_I27_I1.2150.95
598_L617_F1.2120.95
188_E210_T1.2120.95
101_A105_E1.2050.95
423_V478_Y1.2040.95
445_E454_A1.2030.95
240_R280_N1.1990.95
86_E90_H1.1950.94
136_S155_Y1.1910.94
576_E579_Q1.1900.94
271_I281_A1.1900.94
87_L134_V1.1870.94
336_S347_D1.1860.94
590_E593_S1.1860.94
267_T368_L1.1850.94
442_D445_E1.1830.94
451_E536_H1.1820.94
267_T364_E1.1800.94
263_D287_E1.1770.94
84_K88_E1.1740.94
64_V191_L1.1670.94
532_R541_A1.1630.94
210_T230_Q1.1630.94
387_L402_L1.1600.94
28_F128_V1.1510.93
409_Y441_Y1.1510.93
23_T343_M1.1460.93
43_I165_V1.1460.93
66_A73_L1.1420.93
431_K482_E1.1390.93
515_E519_I1.1390.93
597_N616_E1.1360.93
2_A88_E1.1290.93
389_F393_N1.1260.92
135_I144_A1.1230.92
455_D534_K1.1210.92
455_D535_S1.1210.92
249_E252_E1.1130.92
74_T170_I1.1120.92
505_E574_N1.1000.92
529_I573_P1.1000.92
66_A187_E1.0990.92
594_L620_N1.0980.92
26_E197_K1.0900.91
445_E462_Y1.0890.91
573_P576_E1.0850.91
84_K145_Y1.0840.91
40_I78_T1.0830.91
238_I250_D1.0790.91
376_Y405_L1.0690.90
581_L595_Y1.0630.90
388_K468_D1.0620.90
148_E158_E1.0600.90
73_L191_L1.0590.90
63_K209_D1.0560.90
324_S389_F1.0550.90
617_F621_I1.0520.90
302_L319_L1.0500.90
130_D150_A1.0500.90
4_K155_Y1.0450.89
414_K445_E1.0440.89
243_K246_L1.0420.89
251_Y284_F1.0390.89
391_V471_A1.0360.89
90_H96_K1.0350.89
61_Y78_T1.0340.89
236_V241_K1.0330.89
380_Y387_L1.0330.89
32_L125_A1.0320.89
285_V326_V1.0310.89
252_E256_A1.0280.89
146_K160_C1.0240.88
618_T622_C1.0230.88
495_T498_D1.0170.88
391_V406_L1.0090.88
410_S425_R1.0000.87
440_S443_R0.9960.87
29_L73_L0.9910.87
529_I571_I0.9890.87
73_L173_I0.9890.87
160_C163_D0.9880.87
289_M382_S0.9800.86
175_E183_D0.9750.86
426_M430_Q0.9750.86
513_F529_I0.9730.86
322_H398_N0.9720.86
373_R407_L0.9640.85
366_Q370_K0.9630.85
88_E155_Y0.9620.85
34_S309_V0.9620.85
450_T460_I0.9560.85
83_T141_S0.9560.85
84_K143_E0.9550.85
60_Y78_T0.9530.85
65_A74_T0.9530.85
210_T228_E0.9510.84
60_Y165_V0.9440.84
519_I593_S0.9430.84
192_K208_M0.9420.84
515_E589_K0.9410.84
579_Q583_D0.9380.84
91_L157_I0.9380.84
525_K545_E0.9320.83
271_I360_K0.9310.83
431_K492_G0.9310.83
46_K49_T0.9290.83
266_L368_L0.9280.83
361_I365_L0.9270.83
234_S257_E0.9260.83
17_M21_I0.9250.83
580_T583_D0.9240.83
597_N601_N0.9220.82
241_K245_E0.9220.82
310_L313_N0.9210.82
192_K210_T0.9190.82
19_N174_K0.9130.82
3_K154_G0.9130.82
450_T462_Y0.9110.82
307_N332_S0.9070.81
43_I139_L0.9020.81
100_L104_K0.9020.81
525_K566_E0.9000.81
246_L270_H0.8970.81
208_M232_V0.8970.81
423_V426_M0.8970.81
76_S135_I0.8950.81
68_K183_D0.8950.81
89_Q96_K0.8940.81
377_E407_L0.8940.81
15_D152_A0.8930.80
310_L617_F0.8910.80
550_M554_L0.8890.80
380_Y384_G0.8890.80
376_Y380_Y0.8860.80
583_D587_Q0.8850.80
400_D479_Q0.8850.80
272_S278_R0.8840.80
366_Q401_Q0.8820.80
93_T96_K0.8780.79
538_V599_L0.8770.79
250_D253_K0.8740.79
355_K359_K0.8740.79
360_K363_S0.8730.79
99_S274_D0.8720.79
469_E547_T0.8710.79
507_S514_E0.8640.78
144_A161_E0.8640.78
589_K593_S0.8630.78
517_K521_S0.8620.78
505_E508_K0.8610.78
600_Y604_L0.8610.78
532_R570_E0.8600.78
267_T285_V0.8580.78
269_V364_E0.8540.77
188_E193_A0.8500.77
189_Y193_A0.8450.77
509_Y582_Q0.8430.76
321_D393_N0.8420.76
540_L600_Y0.8410.76
65_A229_E0.8400.76
265_P268_H0.8390.76
605_L611_I0.8390.76
76_S162_K0.8380.76
268_H284_F0.8370.76
302_L330_V0.8350.76
378_T382_S0.8340.76
374_E377_E0.8290.75
283_L361_I0.8290.75
509_Y529_I0.8270.75
72_T172_K0.8250.75
412_K425_R0.8240.75
528_R568_V0.8230.75
406_L471_A0.8150.74
281_A357_I0.8130.74
442_D446_K0.8120.74
287_E375_K0.8110.74
616_E620_N0.8090.73
310_L319_L0.8090.73
419_L461_L0.8080.73
145_Y159_P0.8070.73
55_F58_D0.8070.73
512_L516_M0.8060.73
32_L129_A0.8050.73
146_K161_E0.8040.73
551_E565_A0.8030.73
348_R352_L0.7990.73
4_K84_K0.7980.72
535_S619_N0.7970.72
33_I64_V0.7940.72
92_G155_Y0.7940.72
261_G288_N0.7930.72
266_L375_K0.7890.72
417_V461_L0.7850.71
522_D566_E0.7820.71
303_E313_N0.7800.71
142_E161_E0.7790.71
155_Y455_D0.7780.71
91_L136_S0.7780.71
5_E154_G0.7730.70
125_A129_A0.7730.70
380_Y463_F0.7730.70
6_F18_I0.7720.70
511_D514_E0.7720.70
210_T226_V0.7700.70
617_F620_N0.7670.69
67_D74_T0.7670.69
526_N568_V0.7660.69
523_K612_Q0.7610.69
10_S21_I0.7600.69
577_V625_M0.7600.69
274_D278_R0.7600.69
620_N623_K0.7580.69
51_D54_T0.7550.68
15_D19_N0.7550.68
450_T453_V0.7530.68
579_Q582_Q0.7520.68
521_S566_E0.7520.68
262_F288_N0.7490.68
312_M315_C0.7490.68
604_L609_L0.7480.67
117_Q120_V0.7450.67
601_N604_L0.7440.67
283_L302_L0.7440.67
384_G388_K0.7410.67
184_E187_E0.7400.67
451_E535_S0.7400.67
55_F165_V0.7400.67
43_I282_I0.7370.66
621_I624_V0.7370.66
136_S173_I0.7370.66
53_L56_D0.7360.66
68_K89_Q0.7340.66
278_R333_E0.7340.66
137_K163_D0.7310.66
248_D375_K0.7310.66
523_K604_L0.7300.66
602_Q617_F0.7290.65
409_Y413_E0.7260.65
146_K170_I0.7250.65
289_M293_Y0.7230.65
571_I576_E0.7230.65
551_E555_N0.7220.65
538_V578_F0.7220.65
463_F472_I0.7210.65
398_N401_Q0.7200.65
85_D368_L0.7190.64
137_K142_E0.7190.64
583_D589_K0.7190.64
408_F463_F0.7190.64
595_Y624_V0.7190.64
506_E509_Y0.7190.64
513_F517_K0.7180.64
363_S401_Q0.7150.64
307_N350_L0.7110.64
588_D591_K0.7110.64
412_K454_A0.7100.63
83_T287_E0.7090.63
430_Q458_Y0.7080.63
43_I53_L0.7070.63
169_I371_K0.7070.63
419_L483_F0.7070.63
411_S417_V0.7060.63
192_K196_K0.7040.63
35_N38_D0.7040.63
248_D583_D0.7020.63
547_T550_M0.7010.62
499_Q503_E0.6990.62
444_I462_Y0.6980.62
364_E367_S0.6970.62
381_K409_Y0.6960.62
17_M449_Q0.6950.62
183_D186_L0.6950.62
411_S618_T0.6950.62
511_D516_M0.6940.62
484_K543_D0.6940.62
377_E381_K0.6930.62
144_A164_S0.6910.61
525_K568_V0.6910.61
77_D81_G0.6900.61
285_V361_I0.6890.61
577_V595_Y0.6890.61
417_V424_S0.6890.61
187_E190_R0.6890.61
4_K88_E0.6880.61
441_Y464_T0.6880.61
452_M455_D0.6870.61
622_C625_M0.6850.61
65_A209_D0.6850.61
374_E504_E0.6840.61
29_L191_L0.6830.60
248_D264_K0.6830.60
508_K582_Q0.6830.60
57_K78_T0.6820.60
210_T227_Q0.6820.60
545_E548_I0.6800.60
69_D187_E0.6790.60
446_K619_N0.6790.60
590_E623_K0.6790.60
546_V554_L0.6770.60
583_D586_E0.6750.60
137_K144_A0.6750.60
615_V619_N0.6740.59
359_K363_S0.6720.59
299_E314_K0.6710.59
381_K416_L0.6710.59
515_E596_T0.6710.59
67_D72_T0.6700.59
66_A188_E0.6700.59
322_H394_D0.6680.59
29_L128_V0.6680.59
256_A261_G0.6680.59
70_A374_E0.6670.59
392_Y474_M0.6660.59
137_K160_C0.6650.58
569_L599_L0.6650.58
518_N589_K0.6650.58
322_H539_C0.6640.58
427_P458_Y0.6640.58
193_A197_K0.6620.58
401_Q404_D0.6620.58
580_T595_Y0.6620.58
145_Y157_I0.6620.58
250_D261_G0.6610.58
598_L601_N0.6610.58
551_E564_K0.6600.58
86_E142_E0.6590.58
452_M456_K0.6580.58
45_Y48_L0.6580.58
411_S454_A0.6570.57
57_K165_V0.6570.57
8_A343_M0.6560.57
318_L330_V0.6560.57
154_G355_K0.6550.57
15_D18_I0.6550.57
62_I85_D0.6550.57
238_I520_L0.6540.57
246_L253_K0.6530.57
39_A167_T0.6530.57
306_S311_I0.6530.57
42_K102_F0.6520.57
455_D605_L0.6520.57
91_L302_L0.6520.57
321_D547_T0.6500.57
10_S153_D0.6500.57
33_I311_I0.6500.57
62_I206_I0.6490.57
346_H351_K0.6470.56
549_E553_I0.6470.56
46_K51_D0.6470.56
532_R539_C0.6460.56
586_E591_K0.6460.56
558_P563_V0.6460.56
512_L578_F0.6450.56
65_A73_L0.6440.56
86_E140_G0.6400.56
54_T165_V0.6390.55
141_S145_Y0.6390.55
592_L607_E0.6380.55
65_A168_D0.6380.55
329_M617_F0.6380.55
513_F526_N0.6380.55
134_V157_I0.6370.55
451_E455_D0.6360.55
574_N579_Q0.6350.55
276_A352_L0.6340.55
31_E35_N0.6320.55
386_Q389_F0.6300.54
594_L597_N0.6290.54
143_E161_E0.6290.54
363_S366_Q0.6290.54
137_K141_S0.6290.54
85_D88_E0.6280.54
106_N324_S0.6270.54
52_A55_F0.6270.54
399_K474_M0.6260.54
516_M519_I0.6260.54
369_L373_R0.6260.54
317_D354_A0.6250.54
91_L360_K0.6250.54
47_A60_Y0.6250.54
148_E593_S0.6250.54
425_R462_Y0.6250.54
14_L17_M0.6250.54
251_Y255_Y0.6250.54
368_L372_D0.6240.54
368_L375_K0.6240.54
100_L483_F0.6240.54
319_L358_S0.6240.54
297_E316_A0.6220.53
82_M87_L0.6210.53
84_K136_S0.6210.53
346_H349_Q0.6200.53
30_R35_N0.6190.53
502_S531_K0.6190.53
592_L595_Y0.6180.53
11_K152_A0.6180.53
200_D257_E0.6170.53
428_E457_G0.6170.53
277_V352_L0.6160.53
71_R186_L0.6160.53
411_S450_T0.6160.53
126_F191_L0.6150.53
497_E506_E0.6150.53
111_G246_L0.6150.53
284_F402_L0.6140.52
17_M368_L0.6140.52
266_L382_S0.6130.52
357_I382_S0.6130.52
516_M527_V0.6130.52
238_I332_S0.6110.52
399_K403_K0.6100.52
490_D530_S0.6090.52
5_E11_K0.6090.52
502_S505_E0.6090.52
514_E517_K0.6080.52
441_Y454_A0.6080.52
201_F235_M0.6080.52
70_A74_T0.6080.52
17_M549_E0.6070.52
23_T470_F0.6070.52
101_A397_A0.6070.52
71_R176_N0.6070.52
258_K262_F0.6060.52
10_S99_S0.6060.52
283_L328_G0.6060.52
197_K351_K0.6050.51
142_E145_Y0.6040.51
173_I195_I0.6040.51
429_E432_F0.6040.51
447_L601_N0.6040.51
207_K210_T0.6030.51
442_D516_M0.6030.51
17_M389_F0.6020.51
293_Y386_Q0.6010.51
452_M491_L0.6010.51
87_L169_I0.6010.51
503_E616_E0.6000.51
617_F625_M0.5990.51
151_G279_Y0.5990.51
136_S146_K0.5990.51
135_I161_E0.5990.51
185_F241_K0.5980.51
226_V229_E0.5980.51
246_L268_H0.5970.50
117_Q307_N0.5970.50
510_K518_N0.5970.50
424_S459_E0.5970.50
25_K37_S0.5960.50
508_K511_D0.5960.50
265_P331_D0.5960.50
442_D612_Q0.5950.50
237_P259_H0.5950.50
24_Q346_H0.5940.50
356_N360_K0.5930.50
415_K421_E0.5930.50
103_K577_V0.5920.50
99_S306_S0.5920.50
365_L405_L0.5920.50
6_F9_E0.5910.50
47_A54_T0.5900.50
377_E416_L0.5890.50
392_Y470_F0.5890.50
138_A165_V0.5880.49
30_R38_D0.5860.49
542_A547_T0.5860.49
433_I608_G0.5860.49
46_K80_I0.5860.49
96_K302_L0.5850.49
431_K481_K0.5850.49
24_Q344_L0.5840.49
291_F297_E0.5820.49
155_Y512_L0.5810.49
498_D501_Q0.5810.49
528_R570_E0.5810.49
518_N593_S0.5800.48
80_I357_I0.5800.48
504_E510_K0.5790.48
274_D282_I0.5790.48
294_Y471_A0.5780.48
135_I163_D0.5780.48
73_L125_A0.5760.48
362_K402_L0.5760.48
6_F325_F0.5760.48
433_I436_A0.5760.48
297_E439_D0.5760.48
412_K459_E0.5750.48
400_D478_Y0.5750.48
133_T160_C0.5740.48
48_L402_L0.5740.48
80_I184_E0.5740.48
459_E462_Y0.5730.48
272_S281_A0.5730.48
247_T284_F0.5730.48
395_F399_K0.5720.48
447_L451_E0.5720.48
311_I337_L0.5710.47
595_Y625_M0.5690.47
127_M609_L0.5680.47
331_D390_G0.5660.47
69_D226_V0.5650.47
301_G410_S0.5650.47
355_K481_K0.5640.47
203_R549_E0.5640.47
512_L583_D0.5630.46
363_S371_K0.5630.46
424_S427_P0.5620.46
130_D444_I0.5620.46
257_E260_Y0.5620.46
27_I120_V0.5600.46
312_M453_V0.5590.46
289_M294_Y0.5590.46
200_D234_S0.5590.46
482_E506_E0.5580.46
305_Y309_V0.5580.46
75_I171_L0.5580.46
27_I124_A0.5570.46
352_L356_N0.5570.46
328_G345_Q0.5560.46
431_K480_E0.5560.46
160_C164_S0.5550.46
195_I513_F0.5540.45
266_L378_T0.5540.45
451_E454_A0.5540.45
530_S533_L0.5530.45
504_E550_M0.5530.45
508_K579_Q0.5520.45
496_D500_K0.5520.45
250_D281_A0.5500.45
294_Y386_Q0.5500.45
399_K512_L0.5480.45
30_R341_R0.5480.45
433_I481_K0.5480.45
191_L206_I0.5480.45
24_Q322_H0.5470.45
430_Q434_Y0.5470.45
436_A518_N0.5470.45
210_T232_V0.5460.44
26_E405_L0.5460.44
275_G313_N0.5460.44
352_L355_K0.5450.44
61_Y229_E0.5450.44
285_V428_E0.5440.44
196_K234_S0.5440.44
269_V418_S0.5430.44
299_E581_L0.5430.44
424_S479_Q0.5430.44
423_V433_I0.5430.44
12_R16_M0.5420.44
400_D477_S0.5410.44
263_D332_S0.5410.44
127_M364_E0.5410.44
397_A400_D0.5410.44
86_E578_F0.5400.44
10_S114_I0.5390.44
596_T600_Y0.5390.44
267_T375_K0.5390.44
29_L430_Q0.5390.44
516_M521_S0.5390.44
23_T342_E0.5380.44
528_R543_D0.5380.44
24_Q347_D0.5360.43
616_E619_N0.5360.43
488_S545_E0.5360.43
12_R15_D0.5350.43
174_K177_T0.5350.43
257_E262_F0.5350.43
53_L140_G0.5350.43
53_L139_L0.5350.43
553_I556_A0.5340.43
471_A474_M0.5340.43
94_I125_A0.5330.43
512_L582_Q0.5330.43
591_K595_Y0.5330.43
546_V553_I0.5330.43
437_T469_E0.5320.43
89_Q136_S0.5320.43
427_P431_K0.5310.43
545_E551_E0.5310.43
10_S306_S0.5300.43
233_N239_W0.5300.43
438_G443_R0.5290.43
54_T60_Y0.5290.43
59_S205_P0.5290.43
162_K508_K0.5290.43
37_S233_N0.5290.43
162_K313_N0.5280.42
254_F410_S0.5280.42
553_I557_M0.5280.42
366_Q369_L0.5270.42
517_K522_D0.5270.42
20_S199_S0.5260.42
53_L165_V0.5260.42
159_P163_D0.5260.42
10_S13_L0.5260.42
23_T344_L0.5260.42
261_G264_K0.5240.42
284_F321_D0.5240.42
36_S175_E0.5230.42
602_Q606_I0.5230.42
152_A486_V0.5230.42
155_Y518_N0.5230.42
100_L307_N0.5230.42
192_K512_L0.5230.42
290_P294_Y0.5220.42
322_H376_Y0.5220.42
430_Q493_I0.5210.42
34_S198_Y0.5210.42
91_L145_Y0.5210.42
157_I555_N0.5210.42
404_D423_V0.5200.41
538_V606_I0.5200.41
113_D604_L0.5200.41
145_Y160_C0.5200.41
582_Q586_E0.5200.41
37_S261_G0.5190.41
26_E184_E0.5190.41
12_R91_L0.5190.41
309_V575_H0.5190.41
52_A597_N0.5180.41
486_V491_L0.5180.41
548_I567_K0.5180.41
426_M435_Y0.5180.41
300_K321_D0.5180.41
318_L555_N0.5170.41
15_D155_Y0.5170.41
391_V394_D0.5170.41
361_I378_T0.5170.41
362_K387_L0.5170.41
247_T474_M0.5160.41
581_L608_G0.5160.41
191_L232_V0.5160.41
544_G568_V0.5150.41
3_K150_A0.5150.41
276_A439_D0.5150.41
548_I551_E0.5150.41
67_D571_I0.5150.41
22_Y35_N0.5140.41
601_N617_F0.5140.41
275_G617_F0.5140.41
210_T225_E0.5130.41
51_D190_R0.5130.41
57_K206_I0.5130.41
91_L155_Y0.5130.41
391_V402_L0.5120.41
337_L390_G0.5120.41
386_Q391_V0.5120.41
246_L587_Q0.5120.41
406_L472_I0.5120.41
508_K576_E0.5110.40
339_I343_M0.5110.40
155_Y363_S0.5110.40
251_Y254_F0.5110.40
318_L357_I0.5100.40
305_Y332_S0.5100.40
72_T374_E0.5100.40
64_V571_I0.5090.40
270_H284_F0.5090.40
369_L377_E0.5090.40
377_E625_M0.5090.40
170_I501_Q0.5090.40
100_L269_V0.5080.40
492_G495_T0.5080.40
531_K576_E0.5080.40
53_L57_K0.5080.40
9_E13_L0.5080.40
149_S155_Y0.5080.40
332_S335_L0.5080.40
522_D535_S0.5070.40
484_K490_D0.5070.40
330_V513_F0.5070.40
450_T485_S0.5070.40
13_L101_A0.5060.40
296_K312_M0.5060.40
40_I47_A0.5060.40
135_I625_M0.5060.40
9_E16_M0.5060.40
602_Q605_L0.5060.40
138_A141_S0.5060.40
410_S505_E0.5060.40
71_R463_F0.5050.40
367_S428_E0.5040.40
41_D94_I0.5040.40
479_Q510_K0.5040.40
201_F356_N0.5040.40
292_D296_K0.5040.40
228_E358_S0.5030.40
296_K315_C0.5030.40
96_K350_L0.5030.40
250_D495_T0.5030.40
200_D253_K0.5030.40
287_E382_S0.5020.39
540_L573_P0.5020.39
591_K596_T0.5010.39
252_E568_V0.5010.39
606_I618_T0.5010.39
540_L569_L0.5010.39
268_H282_I0.5010.39
370_K420_D0.5010.39
45_Y332_S0.5010.39
202_I356_N0.5010.39
299_E321_D0.5000.39
82_M169_I0.5000.39
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2cg9A 2 0.9633 100 0.158 Contact Map
2ioqA 2 0.9249 100 0.193 Contact Map
2o1uA 2 0.8866 100 0.196 Contact Map
4ivgA 4 0.7236 100 0.227 Contact Map
4ipeA 2 0.9313 100 0.231 Contact Map
1y4sA 2 0.746 100 0.264 Contact Map
3q6mA 4 0.5815 100 0.441 Contact Map
3hjcA 5 0.6006 100 0.442 Contact Map
2cgeA 6 0.6214 100 0.45 Contact Map
2gq0A 1 0.4185 100 0.564 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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