GREMLIN Database
YQBQ - Uncharacterized protein YqbQ
UniProt: P45950 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 326 (298)
Sequences: 365 (316)
Seq/√Len: 18.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
97_Y114_D6.1151.00
203_K220_S5.1871.00
275_L296_I5.1021.00
63_E66_R3.9161.00
104_A148_L3.8141.00
157_R172_A3.6931.00
94_K233_Y3.2340.99
71_S194_S3.0010.99
105_D122_I2.9590.99
95_D205_K2.9030.99
247_Q251_K2.8720.99
271_G308_H2.8600.99
115_F140_L2.8590.99
99_F107_I2.8120.98
75_E190_G2.7710.98
33_I57_F2.6750.98
118_P167_K2.6190.97
95_D143_M2.6050.97
220_S225_I2.5050.96
70_F88_Q2.4530.96
24_G299_D2.4330.96
24_G31_R2.3550.95
107_I147_A2.3550.95
94_K139_S2.3440.95
123_A175_D2.2750.94
224_G258_K2.2720.94
36_K80_T2.1600.92
182_L188_I2.1430.92
205_K232_Q2.1300.92
125_T151_T2.0780.90
162_Y279_L2.0280.89
112_A168_L1.9570.88
104_A129_I1.9250.87
93_N235_E1.8800.85
99_F110_R1.8740.85
69_V81_F1.8340.84
106_E128_T1.8220.83
199_D261_K1.8100.83
203_K225_I1.8040.83
115_F230_V1.7580.81
51_E195_T1.7180.80
264_L285_I1.7070.79
207_R236_T1.7050.79
203_K230_V1.6610.77
34_T290_V1.6560.77
151_T170_L1.6540.77
20_V57_F1.6520.77
102_Q110_R1.6440.76
40_K69_V1.6400.76
49_V69_V1.6360.76
105_D124_N1.6260.76
110_R114_D1.6020.74
269_A310_M1.6020.74
70_F89_Y1.5920.74
297_D315_V1.5750.73
21_S302_E1.5720.73
88_Q198_N1.5370.71
268_Q311_T1.5310.71
35_A55_V1.5210.70
117_I168_L1.5130.70
101_N196_S1.5120.70
191_Y285_I1.5110.70
105_D125_T1.5090.70
14_E69_V1.5050.70
111_L140_L1.4480.67
103_R124_N1.4400.66
97_Y143_M1.4400.66
200_T228_Y1.4270.65
65_F83_A1.4120.65
105_D126_G1.4070.64
279_L296_I1.4060.64
73_N194_S1.3960.64
241_I246_L1.3910.63
89_Y278_G1.3780.63
35_A81_F1.3770.63
250_A254_Q1.3770.63
124_N151_T1.3700.62
84_Y310_M1.3620.62
140_L143_M1.3570.61
213_K255_A1.3540.61
123_A137_D1.3540.61
284_S291_K1.3490.61
163_S228_Y1.3410.60
89_Y231_L1.3360.60
296_I310_M1.3250.59
298_T313_D1.3190.59
194_S263_E1.3150.59
283_I311_T1.3090.58
22_L299_D1.2980.58
170_L205_K1.2920.57
97_Y140_L1.2840.57
105_D151_T1.2810.57
118_P213_K1.2800.57
285_I288_V1.2720.56
102_Q107_I1.2700.56
183_E187_N1.2630.56
157_R174_P1.2560.55
31_R299_D1.2420.54
119_T290_V1.2390.54
84_Y87_L1.2340.54
201_A257_K1.2310.54
198_N272_I1.2310.54
63_E165_K1.2280.54
103_R216_T1.2220.53
51_E260_V1.2160.53
129_I147_A1.2030.52
94_K137_D1.1940.51
120_T167_K1.1900.51
93_N141_Y1.1600.49
215_Y218_T1.1600.49
133_V146_K1.1570.49
89_Y229_G1.1570.49
206_L237_V1.1480.49
23_E300_K1.1430.48
70_F197_I1.1420.48
176_L202_T1.1390.48
23_E32_S1.1250.47
131_S305_G1.1240.47
108_I122_I1.1230.47
283_I287_E1.1160.47
72_R250_A1.1120.46
206_L233_Y1.0970.45
127_Y130_K1.0890.45
58_K63_E1.0740.44
141_Y259_G1.0690.44
36_K269_A1.0540.43
178_E274_D1.0430.42
136_D236_T1.0420.42
25_Q138_T1.0370.42
177_S293_T1.0300.41
107_I143_M1.0290.41
236_T283_I1.0260.41
202_T224_G1.0260.41
241_I249_R1.0220.41
129_I132_L1.0190.41
139_S142_D1.0160.41
127_Y154_Q1.0120.40
191_Y264_L1.0060.40
20_V33_I1.0000.40
108_I148_L0.9950.39
99_F132_L0.9950.39
141_Y145_L0.9900.39
144_I148_L0.9870.39
114_D119_T0.9770.38
262_K286_P0.9710.38
35_A261_K0.9700.38
16_V35_A0.9700.38
84_Y166_G0.9680.38
73_N192_Q0.9570.37
37_I51_E0.9560.37
225_I230_V0.9510.37
26_R151_T0.9500.37
250_A312_I0.9500.37
57_F102_Q0.9490.37
74_P195_T0.9480.37
27_Y250_A0.9460.36
109_K119_T0.9460.36
301_H308_H0.9460.36
70_F84_Y0.9440.36
74_P287_E0.9360.36
138_T175_D0.9360.36
86_M163_S0.9350.36
203_K227_K0.9260.35
152_K256_Q0.9230.35
223_S226_S0.9200.35
169_G283_I0.9180.35
276_Q299_D0.9140.35
211_D298_T0.9130.35
97_Y281_I0.9090.34
96_V205_K0.9040.34
160_Q171_R0.9030.34
181_V281_I0.8990.34
255_A305_G0.8940.33
229_G250_A0.8930.33
151_T205_K0.8890.33
225_I268_Q0.8880.33
155_T303_F0.8830.33
8_K28_Q0.8770.33
99_F114_D0.8740.32
47_Y55_V0.8710.32
35_A88_Q0.8680.32
159_Y206_L0.8680.32
50_S53_D0.8650.32
68_I86_M0.8600.32
297_D313_D0.8600.32
206_L246_L0.8590.32
229_G278_G0.8570.31
19_S36_K0.8530.31
104_A262_K0.8520.31
183_E186_V0.8480.31
269_A309_T0.8450.31
31_R141_Y0.8440.31
34_T82_T0.8440.31
26_R297_D0.8410.31
74_P79_M0.8380.30
277_S299_D0.8330.30
166_G197_I0.8320.30
80_T101_N0.8290.30
103_R122_I0.8240.30
32_S289_G0.8240.30
275_L310_M0.8220.30
23_E34_T0.8220.30
210_K238_S0.8210.30
96_V290_V0.8130.29
92_K141_Y0.8130.29
110_R309_T0.8130.29
92_K139_S0.8070.29
189_T309_T0.8050.29
68_I228_Y0.8000.29
68_I83_A0.7970.28
87_L231_L0.7970.28
150_Q199_D0.7930.28
127_Y151_T0.7890.28
152_K158_N0.7860.28
13_L34_T0.7850.28
149_K209_Q0.7820.28
275_L281_I0.7800.28
38_I263_E0.7770.27
210_K215_Y0.7630.27
201_A233_Y0.7610.27
38_I62_K0.7590.26
171_R176_L0.7580.26
123_A234_V0.7570.26
254_Q263_E0.7540.26
283_I315_V0.7530.26
106_E170_L0.7490.26
37_I262_K0.7450.26
103_R128_T0.7440.26
17_T69_V0.7440.26
75_E196_S0.7420.26
29_A141_Y0.7400.26
206_L234_V0.7390.26
200_T224_G0.7350.25
70_F87_L0.7320.25
22_L150_Q0.7270.25
119_T122_I0.7270.25
102_Q106_E0.7250.25
99_F267_I0.7230.25
25_Q298_T0.7220.25
90_L269_A0.7200.25
21_S34_T0.7200.25
222_S226_S0.7170.25
89_Y277_S0.7090.24
39_T49_V0.7090.24
30_P162_Y0.7080.24
109_K113_R0.7080.24
209_Q214_T0.7070.24
59_W62_K0.7070.24
33_I55_V0.7050.24
84_Y155_T0.7020.24
61_G290_V0.7010.24
20_V48_S0.7000.24
9_E13_L0.7000.24
19_S189_T0.6990.24
69_V83_A0.6990.24
295_W299_D0.6990.24
237_V240_N0.6950.24
299_D303_F0.6950.24
296_I312_I0.6950.24
93_N115_F0.6920.23
25_Q145_L0.6920.23
296_I299_D0.6900.23
142_D191_Y0.6890.23
206_L235_E0.6870.23
36_K78_W0.6870.23
33_I207_R0.6850.23
49_V72_R0.6840.23
158_N290_V0.6820.23
113_R192_Q0.6810.23
32_S299_D0.6800.23
80_T311_T0.6790.23
13_L77_H0.6770.23
189_T267_I0.6730.23
205_K310_M0.6700.22
31_R224_G0.6700.22
20_V37_I0.6670.22
95_D140_L0.6670.22
221_D224_G0.6660.22
96_V129_I0.6620.22
209_Q236_T0.6610.22
204_V207_R0.6600.22
98_V131_S0.6600.22
72_R287_E0.6600.22
192_Q313_D0.6600.22
123_A185_G0.6580.22
115_F174_P0.6570.22
24_G228_Y0.6560.22
120_T169_G0.6550.22
59_W303_F0.6550.22
117_I123_A0.6550.22
16_V311_T0.6540.22
200_T206_L0.6520.22
92_K235_E0.6510.22
24_G224_G0.6480.21
55_V254_Q0.6410.21
129_I154_Q0.6390.21
97_Y111_L0.6390.21
95_D151_T0.6380.21
32_S84_Y0.6370.21
15_L313_D0.6370.21
196_S261_K0.6360.21
53_D227_K0.6360.21
149_K226_S0.6330.21
97_Y110_R0.6320.21
68_I186_V0.6310.21
271_G299_D0.6290.21
119_T144_I0.6290.21
80_T192_Q0.6270.21
162_Y171_R0.6240.21
142_D197_I0.6240.21
71_S198_N0.6220.20
199_D266_S0.6210.20
37_I260_V0.6190.20
162_Y170_L0.6180.20
24_G276_Q0.6170.20
151_T200_T0.6170.20
179_V202_T0.6160.20
217_A228_Y0.6150.20
48_S306_S0.6150.20
113_R129_I0.6140.20
275_L308_H0.6130.20
273_P303_F0.6120.20
40_K287_E0.6120.20
182_L269_A0.6110.20
138_T193_Y0.6090.20
99_F266_S0.6090.20
189_T311_T0.6080.20
70_F147_A0.6070.20
211_D255_A0.6060.20
114_D140_L0.6060.20
291_K296_I0.6050.20
10_T190_G0.6030.20
149_K153_S0.6030.20
68_I119_T0.5990.20
103_R106_E0.5970.19
106_E182_L0.5960.19
193_Y262_K0.5960.19
188_I260_V0.5940.19
113_R213_K0.5920.19
40_K95_D0.5900.19
235_E253_K0.5890.19
36_K57_F0.5890.19
196_S199_D0.5870.19
190_G307_T0.5850.19
203_K226_S0.5840.19
93_N240_N0.5840.19
131_S148_L0.5830.19
24_G295_W0.5820.19
20_V108_I0.5820.19
161_L168_L0.5800.19
83_A144_I0.5800.19
93_N140_L0.5790.19
68_I100_S0.5790.19
78_W159_Y0.5770.19
98_V190_G0.5720.18
176_L281_I0.5720.18
85_D254_Q0.5710.18
77_H107_I0.5710.18
59_W273_P0.5700.18
148_L272_I0.5680.18
129_I269_A0.5670.18
302_E306_S0.5670.18
18_E78_W0.5660.18
55_V144_I0.5660.18
94_K304_K0.5660.18
24_G277_S0.5640.18
126_G151_T0.5640.18
106_E109_K0.5630.18
143_M207_R0.5630.18
14_E19_S0.5630.18
25_Q299_D0.5630.18
208_R279_L0.5610.18
233_Y253_K0.5590.18
278_G301_H0.5570.18
275_L279_L0.5560.18
188_I191_Y0.5560.18
142_D199_D0.5560.18
83_A142_D0.5550.18
281_I314_V0.5550.18
90_L129_I0.5540.18
187_N303_F0.5540.18
87_L163_S0.5530.18
37_I270_I0.5520.18
231_L258_K0.5490.18
51_E57_F0.5490.18
219_A250_A0.5480.18
181_V282_Y0.5470.18
19_S108_I0.5450.17
103_R109_K0.5450.17
25_Q106_E0.5440.17
195_T260_V0.5430.17
70_F166_G0.5430.17
25_Q33_I0.5410.17
138_T146_K0.5380.17
105_D148_L0.5370.17
99_F260_V0.5360.17
90_L144_I0.5350.17
69_V73_N0.5350.17
73_N188_I0.5340.17
17_T238_S0.5340.17
104_A251_K0.5330.17
18_E80_T0.5330.17
37_I49_V0.5330.17
76_E157_R0.5330.17
14_E283_I0.5310.17
204_V254_Q0.5310.17
68_I250_A0.5300.17
116_Q199_D0.5300.17
163_S201_A0.5300.17
229_G254_Q0.5300.17
285_I313_D0.5270.17
105_D170_L0.5250.17
64_L142_D0.5250.17
23_E48_S0.5230.17
179_V271_G0.5230.17
109_K122_I0.5230.17
177_S299_D0.5230.17
182_L303_F0.5220.17
268_Q309_T0.5200.17
111_L139_S0.5190.17
71_S126_G0.5190.17
188_I204_V0.5170.17
111_L168_L0.5160.16
94_K258_K0.5150.16
17_T114_D0.5150.16
199_D304_K0.5140.16
73_N288_V0.5120.16
281_I312_I0.5120.16
107_I132_L0.5100.16
163_S166_G0.5090.16
203_K218_T0.5080.16
303_F308_H0.5080.16
84_Y130_K0.5060.16
40_K311_T0.5060.16
154_Q170_L0.5060.16
22_L105_D0.5040.16
190_G272_I0.5040.16
79_M108_I0.5040.16
10_T93_N0.5040.16
164_A276_Q0.5030.16
100_S270_I0.5030.16
49_V227_K0.5030.16
207_R313_D0.5020.16
109_K226_S0.5010.16
20_V171_R0.5000.16
22_L294_Y0.5000.16
93_N145_L0.5000.16
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3cddA 3 0.9479 100 0.67 Contact Map
3d37A 5 0.9264 100 0.67 Contact Map
1wruA 3 0.9356 100 0.681 Contact Map
3gs9A 3 0.8528 99.8 0.778 Contact Map
2p5zX 3 0.7853 99.3 0.847 Contact Map
4mtkA 4 0.9571 99.3 0.85 Contact Map
2m0oA 1 0.2423 41.6 0.962 Contact Map
2e5pA 1 0.2086 35.4 0.963 Contact Map
2eqjA 1 0.2025 30.7 0.965 Contact Map
2e5qA 1 0.1933 24.9 0.966 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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