GREMLIN Database
YQCI - Uncharacterized protein YqcI
UniProt: P45944 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 254 (216)
Sequences: 417 (301)
Seq/√Len: 20.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
110_E230_R4.4621.00
78_G150_Y4.1601.00
56_A73_L3.9281.00
174_F180_F3.7591.00
118_N122_M3.4741.00
152_V172_L3.3641.00
217_G223_E2.9280.99
58_V73_L2.7140.99
105_K108_D2.5830.98
67_A116_L2.5660.98
164_S201_L2.4500.97
187_T190_G2.3440.96
39_F151_F2.3360.96
132_I142_E2.2380.95
75_T146_N2.2330.95
223_E226_Q2.2260.95
43_P214_G2.1790.94
118_N121_S2.1620.94
34_D38_K2.1170.94
58_V70_L2.0910.93
84_T88_A2.0600.93
217_G226_Q1.9740.91
74_L145_F1.9670.91
190_G224_W1.9640.91
65_E123_E1.9290.90
160_S207_V1.9270.90
153_L175_Q1.9220.90
126_A146_N1.8050.86
175_Q180_F1.8020.86
40_P201_L1.8000.86
28_L93_I1.7770.86
44_G183_L1.7010.83
58_V92_V1.6930.83
117_L198_R1.6900.82
129_P176_P1.6690.82
163_K206_E1.6300.80
175_Q183_L1.6060.79
56_A90_L1.6050.79
136_P210_H1.5450.76
213_L239_C1.5380.76
163_K204_Y1.5130.75
117_L128_W1.4990.74
179_V201_L1.4980.74
62_R96_T1.4950.74
46_Q181_E1.4930.74
26_N30_E1.4880.73
123_E145_F1.4850.73
71_A145_F1.4380.71
59_G95_H1.4350.71
121_S241_F1.4330.71
25_F29_N1.4320.70
25_F48_F1.4310.70
121_S243_K1.4270.70
43_P167_F1.4180.70
75_T125_P1.4050.69
18_P21_Q1.4010.69
47_A89_S1.3620.66
91_T171_M1.3560.66
31_K39_F1.3420.65
118_N136_P1.3340.65
194_S223_E1.3150.64
128_W198_R1.2520.60
94_F136_P1.2270.58
127_D203_A1.2210.58
43_P155_A1.2200.58
134_E225_K1.2160.57
32_I38_K1.2130.57
43_P193_M1.2120.57
93_I142_E1.2050.57
67_A120_L1.2000.56
121_S206_E1.1940.56
47_A53_L1.1760.55
60_D108_D1.1710.55
164_S233_E1.1590.54
70_L116_L1.1500.53
177_R224_W1.1450.53
47_A167_F1.1420.53
42_I45_R1.1380.52
175_Q190_G1.1380.52
30_E112_L1.1370.52
44_G175_Q1.1370.52
110_E234_N1.1260.52
42_I213_L1.1210.51
174_F183_L1.1130.51
39_F47_A1.1120.51
162_R208_P1.1100.51
93_I238_Q1.1060.50
137_D222_L1.1040.50
28_L199_K1.0990.50
106_I228_F1.0700.48
174_F181_E1.0670.48
70_L92_V1.0670.48
61_P86_K1.0630.47
34_D166_S1.0610.47
19_G23_D1.0600.47
91_T238_Q1.0360.46
154_C179_V1.0130.44
183_L193_M1.0030.44
60_D197_I1.0030.44
170_F222_L0.9940.43
141_W229_L0.9850.42
145_F155_A0.9820.42
104_Y108_D0.9800.42
66_T168_P0.9760.42
180_F226_Q0.9750.42
122_M241_F0.9740.42
180_F190_G0.9710.42
153_L174_F0.9700.41
89_S174_F0.9680.41
173_T214_G0.9580.41
189_F200_R0.9520.40
29_N48_F0.9500.40
60_D97_P0.9490.40
61_P112_L0.9490.40
133_P138_N0.9470.40
90_L227_Y0.9430.40
93_I96_T0.9400.40
176_P194_S0.9380.39
64_P119_S0.9330.39
43_P151_F0.9280.39
223_E227_Y0.9230.39
55_I231_D0.9220.38
56_A242_M0.9180.38
32_I51_D0.9130.38
66_T171_M0.9120.38
192_N199_K0.9060.37
216_Y223_E0.9060.37
225_K241_F0.9050.37
177_R226_Q0.9010.37
175_Q207_V0.9000.37
142_E150_Y0.8850.36
153_L229_L0.8770.36
60_D178_W0.8750.36
78_G146_N0.8730.35
184_N210_H0.8720.35
108_D137_D0.8710.35
141_W201_L0.8680.35
127_D146_N0.8580.35
39_F201_L0.8540.34
113_F216_Y0.8520.34
54_R221_N0.8510.34
144_C212_H0.8500.34
142_E154_C0.8500.34
180_F183_L0.8450.34
132_I227_Y0.8360.33
77_Y90_L0.8350.33
98_E105_K0.8320.33
179_V228_F0.8310.33
47_A151_F0.8310.33
53_L91_T0.8280.33
170_F179_V0.8270.33
33_G127_D0.8240.33
132_I144_C0.8190.32
68_K123_E0.8180.32
87_Y186_T0.8170.32
207_V233_E0.8140.32
65_E143_Y0.8140.32
64_P76_R0.8130.32
142_E173_T0.8080.32
151_F164_S0.8000.31
77_Y125_P0.7930.31
48_F55_I0.7930.31
144_C154_C0.7900.31
142_E227_Y0.7880.31
26_N127_D0.7790.30
44_G180_F0.7770.30
39_F155_A0.7760.30
177_R223_E0.7730.30
124_D157_P0.7720.30
50_S77_Y0.7720.30
64_P68_K0.7710.30
117_L123_E0.7690.29
131_D149_P0.7680.29
39_F186_T0.7680.29
149_P183_L0.7650.29
194_S197_I0.7620.29
23_D65_E0.7610.29
162_R210_H0.7590.29
210_H224_W0.7570.29
110_E181_E0.7550.29
179_V207_V0.7540.29
142_E177_R0.7500.28
154_C228_F0.7490.28
175_Q182_D0.7450.28
30_E83_E0.7420.28
105_K206_E0.7370.28
121_S163_K0.7340.28
76_R218_K0.7340.28
139_F222_L0.7340.28
175_Q210_H0.7300.27
201_L229_L0.7270.27
22_L26_N0.7260.27
119_S143_Y0.7260.27
74_L90_L0.7230.27
57_F164_S0.7210.27
40_P93_I0.7190.27
129_P149_P0.7160.27
69_E130_D0.7140.27
110_E212_H0.7130.27
169_Y192_N0.7120.26
177_R190_G0.7060.26
170_F228_F0.6990.26
48_F189_F0.6980.26
110_E211_P0.6960.26
145_F176_P0.6940.26
77_Y187_T0.6940.26
109_Y208_P0.6930.25
66_T71_A0.6880.25
138_N243_K0.6880.25
57_F221_N0.6860.25
89_S242_M0.6780.25
78_G193_M0.6780.25
57_F176_P0.6770.25
72_P195_K0.6740.25
59_G75_T0.6730.25
23_D76_R0.6720.24
149_P174_F0.6710.24
42_I48_F0.6700.24
29_N33_G0.6690.24
161_K201_L0.6660.24
152_V189_F0.6660.24
175_Q187_T0.6650.24
48_F75_T0.6650.24
121_S207_V0.6650.24
44_G174_F0.6640.24
172_L202_E0.6630.24
109_Y162_R0.6600.24
113_F228_F0.6600.24
68_K122_M0.6590.24
115_Q235_Q0.6580.24
46_Q144_C0.6570.24
155_A177_R0.6560.24
210_H228_F0.6550.24
17_L22_L0.6540.24
135_N158_A0.6540.24
45_R207_V0.6530.24
228_F231_D0.6500.23
197_I228_F0.6480.23
176_P216_Y0.6430.23
199_K203_A0.6380.23
39_F176_P0.6300.22
62_R97_P0.6280.22
58_V90_L0.6260.22
153_L190_G0.6260.22
125_P146_N0.6250.22
30_E120_L0.6240.22
39_F193_M0.6230.22
60_D92_V0.6220.22
26_N34_D0.6200.22
142_E175_Q0.6190.22
137_D202_E0.6180.22
27_Y83_E0.6180.22
156_T228_F0.6170.22
43_P216_Y0.6170.22
190_G229_L0.6140.22
78_G122_M0.6130.22
69_E72_P0.6100.22
180_F239_C0.6100.22
29_N118_N0.6080.21
153_L167_F0.6030.21
82_R128_W0.6030.21
132_I216_Y0.6000.21
28_L200_R0.5980.21
174_F222_L0.5980.21
50_S168_P0.5980.21
72_P107_E0.5930.21
142_E222_L0.5910.21
105_K218_K0.5910.21
122_M203_A0.5890.21
105_K126_A0.5820.20
32_I81_S0.5800.20
76_R92_V0.5800.20
85_G167_F0.5800.20
27_Y44_G0.5790.20
152_V196_Q0.5780.20
40_P164_S0.5730.20
99_E107_E0.5720.20
175_Q179_V0.5720.20
38_K142_E0.5710.20
113_F179_V0.5680.20
34_D127_D0.5670.20
62_R116_L0.5650.20
30_E203_A0.5650.20
132_I150_Y0.5630.20
17_L146_N0.5630.20
113_F153_L0.5630.20
148_E178_W0.5610.19
43_P168_P0.5600.19
39_F213_L0.5590.19
140_Q160_S0.5590.19
113_F231_D0.5570.19
144_C174_F0.5540.19
39_F43_P0.5530.19
155_A173_T0.5520.19
63_N119_S0.5520.19
97_P235_Q0.5490.19
155_A170_F0.5480.19
168_P197_I0.5470.19
155_A222_L0.5440.19
142_E179_V0.5430.19
127_D130_D0.5420.19
21_Q178_W0.5400.19
40_P226_Q0.5390.19
64_P122_M0.5370.19
200_R217_G0.5370.19
116_L119_S0.5340.18
45_R193_M0.5320.18
42_I156_T0.5320.18
94_F121_S0.5290.18
155_A210_H0.5290.18
90_L151_F0.5280.18
58_V206_E0.5220.18
204_Y229_L0.5180.18
49_L138_N0.5170.18
59_G186_T0.5170.18
106_I150_Y0.5170.18
99_E104_Y0.5150.18
41_C165_R0.5140.18
198_R215_W0.5130.18
22_L69_E0.5130.18
45_R91_T0.5120.18
55_I180_F0.5110.18
23_D203_A0.5060.17
59_G123_E0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2g18A 3 0.2874 10 0.971 Contact Map
3okpA 1 0.4291 9.3 0.971 Contact Map
1vykA 1 0.3465 6.7 0.973 Contact Map
3efzA 2 0.3543 4.3 0.975 Contact Map
2xciA 3 0.3819 4 0.976 Contact Map
1ucvA 1 0.2953 3.9 0.976 Contact Map
1vsrA 1 0.4134 3.7 0.976 Contact Map
3a98B 1 0.4646 3.7 0.976 Contact Map
2qmaA 2 0.311 3.3 0.977 Contact Map
4mjsA 2 0.1339 3.1 0.977 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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