GREMLIN Database
YQBT - Uncharacterized protein YqbT
UniProt: P45935 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 348 (324)
Sequences: 2534 (2196)
Seq/√Len: 122.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
69_A163_L4.5791.00
84_R151_L4.0951.00
222_D226_S3.8981.00
66_D76_R3.6971.00
257_K334_E3.6901.00
158_E166_R3.6881.00
280_I307_V3.6591.00
331_S334_E3.2801.00
62_G160_D3.2031.00
159_D162_S2.9961.00
87_E148_K2.9451.00
86_G100_F2.8701.00
255_V334_E2.7671.00
110_T116_E2.7651.00
69_A167_Y2.6821.00
6_T9_S2.6551.00
233_D243_A2.6041.00
81_K116_E2.5611.00
99_R106_Y2.5291.00
184_K188_E2.4641.00
298_I336_P2.4601.00
184_K198_V2.3391.00
86_G115_L2.3381.00
277_K281_E2.3231.00
260_E339_G2.3231.00
330_L336_P2.2621.00
220_A253_S2.2561.00
11_M34_L2.1751.00
122_E156_E2.1721.00
281_E285_L2.1081.00
265_V280_I2.1071.00
76_R160_D2.0881.00
93_T112_D2.0781.00
315_D327_N2.0051.00
263_A307_V1.9911.00
88_F100_F1.9711.00
108_Q116_E1.9431.00
66_D160_D1.8911.00
79_A120_A1.8761.00
132_N147_V1.8611.00
68_R71_E1.8511.00
100_F109_Y1.8271.00
89_T144_K1.8181.00
188_E196_V1.8111.00
199_F211_V1.7681.00
107_F126_A1.7221.00
65_L164_R1.7091.00
117_C123_A1.7061.00
187_A210_I1.6931.00
76_R163_L1.6901.00
301_S304_N1.6891.00
82_A124_G1.6871.00
304_N316_Y1.6861.00
189_E231_Y1.6751.00
209_K252_E1.6421.00
99_R108_Q1.6211.00
274_D277_K1.6091.00
117_C124_G1.5981.00
65_L160_D1.5871.00
187_A228_V1.5861.00
204_G207_T1.5641.00
88_F94_I1.5491.00
99_R137_D1.5481.00
127_N130_G1.5411.00
82_A125_N1.5361.00
210_I232_I1.5231.00
282_S286_N1.5181.00
169_T188_E1.5151.00
225_I253_S1.5091.00
283_G310_S1.5091.00
186_W231_Y1.5061.00
108_Q118_E1.4581.00
226_S230_N1.4521.00
86_G145_A1.4291.00
183_Y208_V1.4271.00
13_R40_E1.4191.00
302_Q306_I1.4111.00
74_I163_L1.4061.00
12_D16_N1.3961.00
88_F135_S1.3941.00
105_L124_G1.3781.00
275_Q279_E1.3711.00
88_F109_Y1.3611.00
95_P98_S1.3571.00
121_G125_N1.3481.00
11_M35_A1.3461.00
14_M38_A1.3361.00
31_Y35_A1.3331.00
258_E339_G1.3251.00
212_V228_V1.3131.00
211_V252_E1.3091.00
133_L147_V1.3061.00
15_L31_Y1.3021.00
62_G76_R1.3011.00
287_L306_I1.2981.00
288_F338_L1.2951.00
258_E337_K1.2881.00
79_A157_E1.2841.00
187_A196_V1.2761.00
129_S146_I1.2701.00
106_Y118_E1.2611.00
161_D164_R1.2581.00
109_Y113_G1.2410.99
267_P276_V1.2400.99
231_Y242_Q1.2350.99
272_S275_Q1.2270.99
130_G133_L1.2260.99
115_L151_L1.2240.99
221_S224_L1.2160.99
190_V228_V1.2150.99
98_S109_Y1.2130.99
180_K200_P1.2120.99
125_N154_G1.2040.99
178_A244_P1.2020.99
102_V105_L1.1980.99
54_L60_A1.1930.99
56_F59_T1.1880.99
229_K233_D1.1880.99
75_E163_L1.1840.99
291_I294_E1.1830.99
97_G108_Q1.1810.99
94_I139_I1.1770.99
128_I150_I1.1760.99
214_N224_L1.1680.99
225_I229_K1.1620.99
62_G66_D1.1580.99
278_Q281_E1.1540.99
100_F135_S1.1430.99
88_F98_S1.1360.99
260_E340_Q1.1180.99
187_A190_V1.1090.99
229_K249_V1.1060.99
126_A151_L1.1050.99
54_L64_F1.1050.99
78_A157_E1.1020.99
102_V126_A1.0940.99
84_R115_L1.0930.99
278_Q282_S1.0910.99
126_A132_N1.0890.99
126_A147_V1.0850.99
96_V112_D1.0830.99
184_K197_K1.0540.98
300_L321_I1.0470.98
14_M34_L1.0350.98
310_S313_V1.0260.98
57_S68_R1.0230.98
23_D28_S1.0170.98
8_E12_D1.0140.98
50_T54_L1.0140.98
88_F145_A1.0130.98
210_I251_V1.0050.98
224_L228_V1.0050.98
201_L207_T1.0050.98
234_P242_Q0.9960.97
50_T61_Q0.9950.97
330_L334_E0.9880.97
7_Y11_M0.9840.97
84_R132_N0.9800.97
212_V225_I0.9790.97
58_D67_R0.9780.97
262_S320_K0.9750.97
297_V329_V0.9740.97
98_S142_L0.9710.97
176_V179_N0.9690.97
259_V298_I0.9650.97
268_E314_S0.9600.97
261_I288_F0.9570.97
83_V116_E0.9540.97
160_D163_L0.9540.97
42_A46_I0.9460.97
177_S182_H0.9410.96
81_K120_A0.9410.96
297_V330_L0.9350.96
132_N151_L0.9350.96
69_A74_I0.9340.96
41_L44_S0.9280.96
224_L227_K0.9260.96
21_D24_K0.9260.96
87_E146_I0.9230.96
301_S308_Y0.9200.96
10_I13_R0.9190.96
257_K330_L0.9170.96
220_A224_L0.9170.96
105_L117_C0.9150.96
313_V316_Y0.9090.96
101_Y136_L0.9090.96
262_S322_N0.9070.96
93_T114_T0.9020.95
83_V110_T0.9000.95
193_V212_V0.8990.95
95_P112_D0.8980.95
300_L304_N0.8960.95
10_I40_E0.8950.95
82_A151_L0.8860.95
21_D30_I0.8830.95
74_I167_Y0.8810.95
68_R72_A0.8790.95
101_Y106_Y0.8780.95
48_L51_V0.8780.95
106_Y136_L0.8760.95
185_Q189_E0.8740.95
72_A167_Y0.8720.95
299_R315_D0.8710.94
146_I150_I0.8690.94
184_K195_K0.8650.94
9_S13_R0.8640.94
183_Y186_W0.8550.94
176_V182_H0.8530.94
207_T250_T0.8520.94
135_S142_L0.8510.94
45_Y48_L0.8460.94
182_H186_W0.8410.93
213_T335_I0.8410.93
234_P243_A0.8410.93
283_G306_I0.8400.93
202_W209_K0.8380.93
77_T162_S0.8350.93
123_A156_E0.8340.93
57_S164_R0.8320.93
305_N308_Y0.8270.93
41_L45_Y0.8270.93
163_L167_Y0.8260.93
212_V251_V0.8240.93
181_A184_K0.8180.92
13_R17_S0.8170.92
243_A249_V0.8120.92
85_A149_E0.8100.92
72_A171_V0.8080.92
88_F142_L0.8080.92
59_T64_F0.8060.92
27_G31_Y0.8060.92
67_R70_T0.8030.92
29_V32_N0.8000.92
183_Y244_P0.7980.91
63_E67_R0.7930.91
276_V310_S0.7930.91
14_M41_L0.7880.91
57_S167_Y0.7880.91
82_A107_F0.7860.91
100_F147_V0.7860.91
302_Q305_N0.7860.91
192_G215_A0.7850.91
57_S71_E0.7840.91
300_L327_N0.7840.91
276_V279_E0.7840.91
228_V251_V0.7830.91
14_M37_V0.7820.91
132_N145_A0.7820.91
37_V51_V0.7780.90
225_I251_V0.7780.90
231_Y234_P0.7760.90
276_V312_S0.7750.90
188_E195_K0.7740.90
284_V307_V0.7740.90
287_L291_I0.7700.90
11_M15_L0.7690.90
214_N221_S0.7680.90
117_C121_G0.7630.90
260_E322_N0.7630.90
65_L163_L0.7600.89
178_A186_W0.7590.89
243_A246_G0.7590.89
268_E271_S0.7580.89
281_E340_Q0.7570.89
296_N302_Q0.7510.89
202_W207_T0.7460.88
209_K333_V0.7440.88
203_N209_K0.7420.88
84_R150_I0.7420.88
58_D70_T0.7390.88
285_L339_G0.7340.88
72_A170_R0.7340.88
211_V333_V0.7340.88
286_N290_K0.7310.87
26_E35_A0.7270.87
27_G32_N0.7250.87
77_T155_R0.7220.87
81_K119_T0.7210.87
116_E119_T0.7200.87
52_L56_F0.7180.87
54_L61_Q0.7180.87
98_S135_S0.7150.86
190_V231_Y0.7130.86
183_Y247_A0.7110.86
187_A198_V0.7100.86
110_T113_G0.7090.86
187_A232_I0.7090.86
135_S139_I0.7080.86
82_A153_P0.7010.85
171_V174_E0.6990.85
128_I148_K0.6990.85
36_P39_A0.6980.85
60_A164_R0.6970.85
186_W189_E0.6970.85
105_L119_T0.6960.85
225_I254_A0.6940.85
18_I30_I0.6910.84
302_Q308_Y0.6900.84
6_T45_Y0.6890.84
256_W337_K0.6890.84
80_T155_R0.6870.84
28_S31_Y0.6870.84
18_I35_A0.6860.84
115_L145_A0.6850.84
128_I149_E0.6840.84
92_V139_I0.6830.84
287_L290_K0.6810.83
323_G334_E0.6810.83
265_V313_V0.6760.83
11_M14_M0.6740.83
220_A225_I0.6740.83
187_A212_V0.6730.83
69_A171_V0.6730.83
263_A280_I0.6720.83
183_Y187_A0.6700.82
194_G213_T0.6690.82
305_N309_N0.6690.82
283_G309_N0.6680.82
66_D163_L0.6670.82
195_K213_T0.6660.82
107_F151_L0.6620.82
159_D163_L0.6610.82
10_I45_Y0.6610.82
17_S39_A0.6600.82
285_L289_K0.6600.82
30_I33_A0.6590.81
179_N182_H0.6590.81
19_S22_I0.6560.81
119_T124_G0.6560.81
285_L338_L0.6550.81
102_V132_N0.6540.81
56_F60_A0.6520.81
49_D52_L0.6490.80
159_D164_R0.6480.80
84_R148_K0.6460.80
223_I227_K0.6430.80
289_K293_F0.6430.80
302_Q315_D0.6410.80
77_T166_R0.6410.80
58_D168_F0.6400.80
196_V210_I0.6390.79
190_V227_K0.6370.79
279_E282_S0.6360.79
173_R181_A0.6360.79
105_L123_A0.6350.79
57_S65_L0.6340.79
94_I157_E0.6340.79
267_P270_N0.6330.79
175_A242_Q0.6330.79
177_S186_W0.6320.79
98_S139_I0.6320.79
220_A228_V0.6320.79
259_V336_P0.6310.79
165_A169_T0.6310.79
13_R16_N0.6300.78
15_L24_K0.6290.78
182_H185_Q0.6290.78
301_S316_Y0.6280.78
33_A36_P0.6240.78
82_A121_G0.6220.78
202_W250_T0.6220.78
56_F167_Y0.6190.77
39_A43_K0.6180.77
252_E333_V0.6170.77
167_Y171_V0.6170.77
24_K31_Y0.6150.77
280_I283_G0.6140.77
206_G225_I0.6110.76
95_P109_Y0.6110.76
194_G215_A0.6080.76
22_I25_R0.6050.76
63_E66_D0.6040.76
190_V242_Q0.6030.75
32_N35_A0.6010.75
109_Y115_L0.6000.75
99_R136_L0.5980.75
84_R153_P0.5930.74
209_K250_T0.5930.74
82_A122_E0.5910.74
298_I330_L0.5910.74
83_V152_I0.5900.74
17_S20_A0.5890.74
101_Y104_N0.5880.74
267_P277_K0.5870.73
76_R157_E0.5860.73
107_F147_V0.5860.73
147_V150_I0.5860.73
65_L167_Y0.5850.73
126_A130_G0.5850.73
49_D53_E0.5830.73
23_D48_L0.5830.73
226_S229_K0.5810.73
14_M17_S0.5790.72
29_V33_A0.5790.72
222_D253_S0.5790.72
70_T76_R0.5760.72
33_A37_V0.5760.72
287_L303_I0.5730.72
15_L35_A0.5710.71
77_T158_E0.5700.71
40_E43_K0.5690.71
252_E303_I0.5680.71
195_K294_E0.5660.71
121_G156_E0.5660.71
50_T53_E0.5640.71
111_A114_T0.5590.70
78_A301_S0.5570.70
92_V95_P0.5560.69
170_R175_A0.5550.69
47_W51_V0.5550.69
299_R327_N0.5540.69
213_T254_A0.5540.69
51_V55_V0.5520.69
17_S40_E0.5520.69
271_S312_S0.5500.69
27_G35_A0.5490.68
219_P256_W0.5490.68
320_K324_V0.5480.68
300_L324_V0.5470.68
44_S47_W0.5460.68
337_K340_Q0.5450.68
321_I330_L0.5450.68
92_V141_G0.5430.68
29_V56_F0.5420.67
147_V151_L0.5420.67
212_V224_L0.5400.67
221_S228_V0.5380.67
60_A69_A0.5380.67
172_R181_A0.5370.67
299_R304_N0.5370.67
19_S24_K0.5360.67
7_Y39_A0.5360.67
60_A65_L0.5350.66
12_D309_N0.5340.66
43_K46_I0.5330.66
229_K251_V0.5330.66
188_E191_D0.5300.66
96_V110_T0.5290.66
86_G147_V0.5280.65
286_N289_K0.5270.65
135_S145_A0.5270.65
100_F133_L0.5270.65
193_V196_V0.5260.65
175_A182_H0.5260.65
264_E320_K0.5250.65
10_I41_L0.5250.65
186_W232_I0.5250.65
210_I228_V0.5240.65
255_V333_V0.5240.65
129_S148_K0.5220.65
289_K294_E0.5220.65
214_N256_W0.5210.64
55_V68_R0.5200.64
200_P204_G0.5200.64
283_G286_N0.5180.64
18_I24_K0.5180.64
92_V114_T0.5180.64
115_L133_L0.5160.64
32_N36_P0.5160.64
221_S231_Y0.5150.64
39_A46_I0.5150.64
100_F151_L0.5150.64
170_R174_E0.5150.64
284_V308_Y0.5120.63
128_I147_V0.5110.63
137_D226_S0.5090.63
81_K110_T0.5090.63
251_V303_I0.5090.63
302_Q309_N0.5080.63
181_A185_Q0.5080.63
52_L71_E0.5080.63
76_R166_R0.5070.62
166_R189_E0.5060.62
194_G214_N0.5060.62
49_D64_F0.5060.62
52_L55_V0.5060.62
94_I142_L0.5050.62
298_I327_N0.5050.62
80_T110_T0.5040.62
223_I336_P0.5040.62
78_A292_A0.5020.62
101_Y134_L0.5020.62
77_T189_E0.5020.62
292_A336_P0.5010.61
28_S59_T0.5010.61
102_V147_V0.5000.61
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3h2tA 2 0.4511 98.6 0.855 Contact Map
3laxA 1 0.2845 41.6 0.951 Contact Map
2y27A 2 0.7328 18.3 0.959 Contact Map
3zieA 2 0.2126 13.9 0.961 Contact Map
3p04A 2 0.1897 13.7 0.961 Contact Map
3zigA 2 0.1925 10.5 0.963 Contact Map
2y4oA 2 0.7241 6.9 0.966 Contact Map
1mdbA 1 0.7385 6.7 0.966 Contact Map
3v9oA 3 0.3247 6.1 0.967 Contact Map
2k6lA 2 0.1466 5.6 0.968 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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